2VCI | Genus

Total Genus 67

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	67
sequence length	208
structure length	208
Chain Sequence	EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 208 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

208 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 72 ms

Adding embedded #jmolscript: select ({0:207});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Chaperone
source organism	Homo sapiens
publication title	4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer. pubmed doi rcsb
molecule keywords	HEAT SHOCK PROTEIN HSP 90-ALPHA
total genus	67
structure length	208
sequence length	208
ec nomenclature
pdb deposition date	2007-09-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02518	HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.565.10	Alpha Beta	2-Layer Sandwich	Heat Shock Protein 90	Histidine kinase-like ATPase, C-terminal domain	2vciA00

4AS9A 4LWEA 1JM6A 1YT1A 1YSZA 2CCTA 1YETA 4L8ZA 3EHJA 1ZXNA 1Y4UA 1YSRA 2XJGA 2ZBKB 5CTUA 4I3HA 4HY6A 4P8OA 3T0HA 4ZVIA 4H7QA 2Q8FA 3TZ5A 3T10A 1YC3A 4HYMA 2XD6A 4E02A 1EA6A 4EGKA 2CGFA 4YKUA 3RLPA 2H8MA 2CH4A 2O1WA 4LWFA 1ZWHA 4BQGA 2VCIA 1UY9A 3CGYA 4URNA 3R4MA 1R62A 4LWIA 4NH9A 3U2KA 4MP7A 4URMA 4L91A 4LPBA 3Q5LA 1AM1A 1TC0A 3GIFA 3U67A 2YEAA 2YKEA 4U7NA 4UROA 4NH8A 4XKOA 4H85A 1BKNA 4KQVA 5IDJA 4FMTA 2BU5A 4XKAA 4XDMA 4YKXA 1AJ6A 2YEIA 1THNA 4MP2A 5IDMA 3R4OA 4V26A 2XDUA 1BYQA 2QG0A 2WI5A 2YE5A 4PRXA 1UYIA 2YI0A 3G7EA 2XHXA 3EHHA 4DZYA 3IEDA 3HYZA 2YEFA 2XDKA 3R92A 3K98A 3TZ0A 4JQLA 3TUHA 1B3QA 1YERA 2Q8HA 1GKXA 2XX4A 1UYCA 1UYMA 1UYKA 5FNCA 4Q20A 1Z5AA 2YI6A 3MNRP 1ZW9A 2ZDYA 2YE3A 5CF0A 2EXLA 3A0RA 5D7RA 4GEEA 1BGQA 1UYFA 4GCZA 4EFUA 4ASGA 4R1FA 1Y8OA 5D6PA 5BOCA 4K4OA 3EKOA 5CTXA 3B25A 5F5RA 3TTZA 1MU5A 1S14A 2YKJA 2H55A 4BIUA 2IWUA 3KE6A 1EI1A 2YJWA 4CWOA 3G7BA 1UYDA 4XIRA 3R4NA 4ASFA 1AH8A 1I5CA 1QYEA 3A0YA 2IWXA 3INWA 4P7AA 3EKRA 4CWFA 3ZXQA 2FXSA 2XDXA 4JAUA 4EFTA 3T2SA 2QFOA 2VW5A 2BYIA 3TZ2A 2XK2A 2BU7A 2CCSA 2XDSA 4QPJA 1UY6A 3QDDA 3CRLA 3T1KA 3D0BA 4JASA 4H81A 4HXWA 2YEJA 4U7OA 4URLA 3LNUA 1BXDA 2WI3A 2CCUA 3OW6A 4PRVA 4XCJA 4CE3A 2WEQA 2YEEA 3DGEA 3HZ1A 1ID0A 4GGLA 2YEDA 3D2RA 3FV5A 2UWDA 4KP4A 1I5DA 4BXIA 4LWHA 1TIDA 4O04A 2BZ5A 2VWCA 1UYGA 2BRCA 1L0OA 3K99A 4WUBA 2Q2EB 3VHAA 4LP0A 4PL9A 4EGIA 1H7SA 3K60A 4FCQA 1KZNA 2ESAA 3Q5KA 4MOTA 1I59A 3B28A 1UYHA 1YT0A 4B6CA 4XCLA 4R3AA 2YE7A 4GT8A 2BTZA 5D7CA 4AWQA 4XIQA 2IOQA 3R4PA 2FWYA 2Q8GA 4KSHA 4LWGA 4EMVA 1I5AA 2BU2A 1YC4A 5FNFA 3CWVA 3FT5A 2XHTA 3B26A 3NMQA 1KIJA 5CTYA 3ZKDA 2JJCA 1YS3A 2XHRA 1TC6A 2YGEA 2ZDXA 2BU6A 4CWPA 3EHFA 3WHAA 2GFDA 1U0ZA 1AH6A 2YKBA 1UYLA 1QY8A 1Z5CA 4EGHA 2XX2A 4I5SA 4CE2A 1Y4SA 3FT8A 4DUHA 4XITA 4YKWA 5M4PA 5C93A 3T0ZA 1H7UA 3ZKBA 1UY8A 4ASBA 4YKYA 3A0TA 2O1VA 4B7PA 4X9LA 4CWRA 4XKKA 2PNRA 3C0EA 1I5BA 1NHJA 2BU8A 3VHCA 2YEHA 2YE9A 3D36A 3INXA 3HYYA 4HZ5A 2YEGA 4L93A 2WERA 2XDLA 2E0AA 4GQTA 4MPNA 2XCMA 5GGZA 2WEPA 4HYPA 4YKZA 4L94A 3Q5JA 4WUCA 2HCHA 2XX5A 3ZXOA 4FPPA 1US7A 2YE2A 3O0IA 4XC0A 1UYEA 4WUDA 1YESA 4YKTA 3G75A 3GIGB 2HG1A 4KSGA 4FCPA 3QTFA 4W7TA 2YK9A 2BREA 3HZ5A 1YT2A 2FYPA 2YI5A 3BM9A 3PEJA 2IORA 4XE2A 1TILA 2ZKJA 4CWSA 4XTJA 2GQPA 1GKZA 2FWZA 4YKRA 2HKJA 2QG2A 4HZ0A 4E01A 4XD8A 4L90A 3GIGA 4MB9A 5M4EA 1AMWA 1QZRA 4ASAA 4MPEA 3B24A 1B63A 3HHUA 2XJXA 3A0WA 4YKQA 5M4HA 3HEKA 3BMYA 3ZM7A 3JZ3A 4U93A 4HY1A 2YE8A 1OSFA 3RLQA 2AKPA 5CPHA 5BODA 2XABA 2JKIA 4AWPA 5M4MA 3VADA 3OPDA 1PVGA 1TBWA 3R91A 5J6AA 4AWOA 4NH7A 4QPKA 2BYHA 2YKIA 2WI2A 3O2FA 3VHDA 5D6QA 4BIZA 1Z5BA 4R3MA 2YGFA 1GJVA 2CG9A 3B27A 4O09A 3H4LA 5F3KA 4BAEA 1ZXMA 2YI7A 3OMUA 4O07A 3U2DA 5FNDA 2WI1A 3OWDA 4V25A 1Z59A 1S16A 1NHIA 1MX0A 3O6OA 5M4NA 2WI6A 4FCRA 2XJJA 2YE6A 4JAVA 4EM7A 2WI4A 4EEHA 5IN9A 4MBCA 4XIPA 3A0ZA 2YECA 4GFNA 2YJXA 4O05A 2YEBA 4KFGA 5L3JA 2YGAA 4E00A 5CTWA 1YC1A 4KTNA 5J71A 3GIEA 1B62A 5M4KA 3RKZA 1I58A 3CRKA 2YK2A 2WI7A 3CGZA 2YKCA 1UY7A 3LPSA 2IOPA 2K5BA 4CE1A 4CWTA 3RLRA 4CWQA 3WQ9A 2IWSA 3EHGA 4ZKIA 5FWKA 1TH8A 2VCJA 1Y8PA 2BT0A 3SL2A 2Q8IA 2BSMA 1A4HA 3H80A 4PU9A 3A0XA 3TZ4A 1U2OA 3OWBA 4MPCA 1Y8NA 4O0BA 2C2AA 3K97A 4BQJA 5D7DA 3PEHA 1NHHA 2O1UA 4HXZA 4CWNA 2QF6A 3C11A 2YE4A
chains in the Genus database with same CATH superfamily

4AS9A 4LWEA 1JM6A 1YT1A 1YSZA 2CCTA 1YETA 4L8ZA 3EHJA 1ZXNA 1Y4UA 1YSRA 2XJGA 2ZBKB 5CTUA 4I3HA 4HY6A 4P8OA 3T0HA 4ZVIA 4H7QA 2Q8FA 3TZ5A 3T10A 1YC3A 4HYMA 2XD6A 4E02A 1EA6A 4EGKA 2CGFA 4YKUA 3RLPA 2H8MA 2CH4A 2O1WA 4LWFA 1ZWHA 4BQGA 2VCIA 1UY9A 3CGYA 4URNA 3R4MA 1R62A 4LWIA 4NH9A 3U2KA 4MP7A 4URMA 4L91A 4E72A 4LPBA 1IXMA 3Q5LA 1AM1A 1TC0A 3GIFA 3U67A 2YEAA 2YKEA 4U7NA 4UROA 4NH8A 4XKOA 4H85A 1BKNA 4KQVA 5IDJA 4FMTA 2BU5A 4XKAA 4XDMA 4YKXA 1AJ6A 2YEIA 1THNA 4MP2A 5IDMA 3R4OA 4V26A 2XDUA 1BYQA 2QG0A 2WI5A 2YE5A 4PRXA 1UYIA 2YI0A 3G7EA 2XHXA 3EHHA 4DZYA 3IEDA 3HYZA 2YEFA 2XDKA 3R92A 3K98A 3TZ0A 4JQLA 3TUHA 1B3QA 1YERA 2Q8HA 1GKXA 2XX4A 1UYCA 1UYMA 1UYKA 5FNCA 4Q20A 1Z5AA 2YI6A 3MNRP 1ZW9A 2ZDYA 2YE3A 5CF0A 2EXLA 3A0RA 5D7RA 4GEEA 1BGQA 1UYFA 4GCZA 4EFUA 4ASGA 4R1FA 1Y8OA 5D6PA 5BOCA 4K4OA 3EKOA 5CTXA 3B25A 5F5RA 3TTZA 1MU5A 1S14A 2YKJA 2H55A 4BIUA 2IWUA 3KE6A 1EI1A 2YJWA 4CWOA 3G7BA 1UYDA 4XIRA 2C1IA 3R4NA 4ASFA 1AH8A 1I5CA 1QYEA 3A0YA 2IWXA 3INWA 3S5TA 4P7AA 3EKRA 4CWFA 3ZXQA 2FXSA 2XDXA 4JAUA 4EFTA 3T2SA 2QFOA 2VW5A 2BYIA 3TZ2A 2XK2A 2BU7A 2CCSA 2XDSA 4QPJA 1UY6A 3QDDA 3CRLA 3T1KA 3D0BA 4JASA 4H81A 2C1GA 4HXWA 2YEJA 4U7OA 4URLA 3LNUA 1BXDA 2WI3A 2CCUA 3OW6A 4PRVA 4XCJA 4CE3A 2WEQA 2YEEA 3DGEA 3HZ1A 1ID0A 4GGLA 2YEDA 3D2RA 3FV5A 2UWDA 4KP4A 1I5DA 4BXIA 3LMMA 4LWHA 1TIDA 5JENA 4O04A 2BZ5A 2VWCA 1UYGA 2BRCA 1L0OA 3K99A 4WUBA 2Q2EB 3VHAA 4LP0A 4PL9A 4EGIA 1H7SA 3K60A 4FCQA 1KZNA 2ESAA 3Q5KA 4MOTA 1I59A 3B28A 1UYHA 1YT0A 4B6CA 4XCLA 4R3AA 2YE7A 4GT8A 2BTZA 5D7CA 4AWQA 4XIQA 2IOQA 3R4PA 2FWYA 2Q8GA 4KSHA 4LWGA 4EMVA 1I5AA 2BU2A 1YC4A 5FNFA 3CWVA 2FTKA 3FT5A 2XHTA 3B26A 3NMQA 1KIJA 5CTYA 3ZKDA 2JJCA 1YS3A 2XHRA 1TC6A 2YGEA 2ZDXA 2BU6A 4CWPA 3EHFA 3WHAA 2GFDA 1U0ZA 1AH6A 2YKBA 1UYLA 1QY8A 1Z5CA 4EGHA 2XX2A 1F51A 4I5SA 4CE2A 1Y4SA 3FT8A 4DUHA 4XITA 4YKWA 5M4PA 5C93A 3T0ZA 1H7UA 3ZKBA 1UY8A 4ASBA 4YKYA 3A0TA 2O1VA 3CYGA 4B7PA 4X9LA 4CWRA 4XKKA 2PNRA 3C0EA 1I5BA 1NHJA 2BU8A 3VHCA 2YEHA 2YE9A 3D36A 3INXA 3HYYA 4HZ5A 2YEGA 4L93A 2WERA 2XDLA 2E0AA 4GQTA 4MPNA 2XCMA 5GGZA 2WEPA 4HYPA 4YKZA 4L94A 3Q5JA 4WUCA 2HCHA 2XX5A 3ZXOA 4FPPA 1US7A 2YE2A 3O0IA 4XC0A 1UYEA 4WUDA 1YESA 4YKTA 3G75A 3GIGB 2HG1A 4KSGA 4FCPA 3QTFA 4W7TA 2YK9A 2BREA 3HZ5A 1YT2A 2FYPA 2YI5A 3BM9A 3PEJA 2IORA 4XE2A 1TILA 2ZKJA 4CWSA 4XTJA 2GQPA 1GKZA 2FWZA 4YKRA 2HKJA 2QG2A 4HZ0A 4E01A 4XD8A 4L90A 3GIGA 4MB9A 5M4EA 1AMWA 1QZRA 4ASAA 4MPEA 3B24A 1B63A 3HHUA 2XJXA 3A0WA 4YKQA 5M4HA 3HEKA 3BMYA 3ZM7A 3JZ3A 4U93A 4HY1A 2YE8A 1OSFA 3RLQA 2AKPA 5CPHA 5BODA 2XABA 2JKIA 4AWPA 5M4MA 3VADA 3OPDA 1PVGA 1TBWA 3R91A 5J6AA 4AWOA 4NH7A 4QPKA 2BYHA 2YKIA 2WI2A 3O2FA 3VHDA 5D6QA 4BIZA 1Z5BA 4R3MA 2YGFA 1GJVA 2CG9A 3B27A 4O09A 3H4LA 5F3KA 4BAEA 1ZXMA 2YI7A 3OMUA 4O07A 3U2DA 5FNDA 2WI1A 3OWDA 4V25A 1Z59A 1S16A 1NHIA 2HHIA 1MX0A 3O6OA 5M4NA 2WI6A 4FCRA 2XJJA 2YE6A 4JAVA 4EM7A 2WI4A 4EEHA 5IN9A 4MBCA 4XIPA 3A0ZA 2YECA 4GFNA 2YJXA 4O05A 2YEBA 4KFGA 5L3JA 2YGAA 4E00A 5CTWA 1YC1A 4KTNA 5J71A 3GIEA 1B62A 5M4KA 3RKZA 1I58A 3CRKA 2YK2A 2WI7A 3CGZA 2YKCA 1UY7A 3LPSA 2IOPA 2K5BA 4CE1A 4CWTA 3RLRA 4CWQA 3WQ9A 2IWSA 3EHGA 4ZKIA 5FWKA 1TH8A 2VCJA 1Y8PA 2BT0A 3SL2A 2Q8IA 2BSMA 1A4HA 3H80A 4PU9A 3A0XA 3TZ4A 1U2OA 3OWBA 4MPCA 1Y8NA 4O0BA 2C2AA 3K97A 4BQJA 5D7DA 3PEHA 1NHHA 2O1UA 4HXZA 4CWNA 2QF6A 3C11A 2YE4A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4AS9 A;  4LWE A;  1JM6 A;  1YT1 A;  1YSZ A;  2CCT A;  1YET A;  4L8Z A;  3EHJ A;  1ZXN A;  1Y4U A;  1YSR A;  2XJG A;  2ZBK B;  5CTU A;  4I3H A;  4HY6 A;  4P8O A;  3T0H A;  4ZVI A;  4H7Q A;  2Q8F A;  3TZ5 A;  3T10 A;  1YC3 A;  4HYM A;  2XD6 A;  4E02 A;  1EA6 A;  4EGK A;  2CGF A;  4YKU A;  3RLP A;  2H8M A;  2CH4 A;  2O1W A;  4LWF A;  1ZWH A;  4BQG A;  2VCI A;  1UY9 A;  3CGY A;  4URN A;  3R4M A;  1R62 A;  4LWI A;  4NH9 A;  3U2K A;  4MP7 A;  4URM A;  4L91 A;  4LPB A;  3Q5L A;  1AM1 A;  1TC0 A;  3GIF A;  3U67 A;  2YEA A;  2YKE A;  4U7N A;  4URO A;  4NH8 A;  4XKO A;  4H85 A;  1BKN A;  4KQV A;  5IDJ A;  4FMT A;  2BU5 A;  4XKA A;  4XDM A;  4YKX A;  1AJ6 A;  2YEI A;  1THN A;  4MP2 A;  5IDM A;  3R4O A;  4V26 A;  2XDU A;  1BYQ A;  2QG0 A;  2WI5 A;  2YE5 A;  4PRX A;  1UYI A;  2YI0 A;  3G7E A;  2XHX A;  3EHH A;  4DZY A;  3IED A;  3HYZ A;  2YEF A;  2XDK A;  3R92 A;  3K98 A;  3TZ0 A;  4JQL A;  3TUH A;  1B3Q A;  1YER A;  2Q8H A;  1GKX A;  2XX4 A;  1UYC A;  1UYM A;  1UYK A;  5FNC A;  4Q20 A;  1Z5A A;  2YI6 A;  3MNR P;  1ZW9 A;  2ZDY A;  2YE3 A;  5CF0 A;  2EXL A;  3A0R A;  5D7R A;  4GEE A;  1BGQ A;  1UYF A;  4GCZ A;  4EFU A;  4ASG A;  4R1F A;  1Y8O A;  5D6P A;  5BOC A;  4K4O A;  3EKO A;  5CTX A;  3B25 A;  5F5R A;  3TTZ A;  1MU5 A;  1S14 A;  2YKJ A;  2H55 A;  4BIU A;  2IWU A;  3KE6 A;  1EI1 A;  2YJW A;  4CWO A;  3G7B A;  1UYD A;  4XIR A;  3R4N A;  4ASF A;  1AH8 A;  1I5C A;  1QYE A;  3A0Y A;  2IWX A;  3INW A;  4P7A A;  3EKR A;  4CWF A;  3ZXQ A;  2FXS A;  2XDX A;  4JAU A;  4EFT A;  3T2S A;  2QFO A;  2VW5 A;  2BYI A;  3TZ2 A;  2XK2 A;  2BU7 A;  2CCS A;  2XDS A;  4QPJ A;  1UY6 A;  3QDD A;  3CRL A;  3T1K A;  3D0B A;  4JAS A;  4H81 A;  4HXW A;  2YEJ A;  4U7O A;  4URL A;  3LNU A;  1BXD A;  2WI3 A;  2CCU A;  3OW6 A;  4PRV A;  4XCJ A;  4CE3 A;  2WEQ A;  2YEE A;  3DGE A;  3HZ1 A;  1ID0 A;  4GGL A;  2YED A;  3D2R A;  3FV5 A;  2UWD A;  4KP4 A;  1I5D A;  4BXI A;  4LWH A;  1TID A;  4O04 A;  2BZ5 A;  2VWC A;  1UYG A;  2BRC A;  1L0O A;  3K99 A;  4WUB A;  2Q2E B;  3VHA A;  4LP0 A;  4PL9 A;  4EGI A;  1H7S A;  3K60 A;  4FCQ A;  1KZN A;  2ESA A;  3Q5K A;  4MOT A;  1I59 A;  3B28 A;  1UYH A;  1YT0 A;  4B6C A;  4XCL A;  4R3A A;  2YE7 A;  4GT8 A;  2BTZ A;  5D7C A;  4AWQ A;  4XIQ A;  2IOQ A;  3R4P A;  2FWY A;  2Q8G A;  4KSH A;  4LWG A;  4EMV A;  1I5A A;  2BU2 A;  1YC4 A;  5FNF A;  3CWV A;  3FT5 A;  2XHT A;  3B26 A;  3NMQ A;  1KIJ A;  5CTY A;  3ZKD A;  2JJC A;  1YS3 A;  2XHR A;  1TC6 A;  2YGE A;  2ZDX A;  2BU6 A;  4CWP A;  3EHF A;  3WHA A;  2GFD A;  1U0Z A;  1AH6 A;  2YKB A;  1UYL A;  1QY8 A;  1Z5C A;  4EGH A;  2XX2 A;  4I5S A;  4CE2 A;  1Y4S A;  3FT8 A;  4DUH A;  4XIT A;  4YKW A;  5M4P A;  5C93 A;  3T0Z A;  1H7U A;  3ZKB A;  1UY8 A;  4ASB A;  4YKY A;  3A0T A;  2O1V A;  4B7P A;  4X9L A;  4CWR A;  4XKK A;  2PNR A;  3C0E A;  1I5B A;  1NHJ A;  2BU8 A;  3VHC A;  2YEH A;  2YE9 A;  3D36 A;  3INX A;  3HYY A;  4HZ5 A;  2YEG A;  4L93 A;  2WER A;  2XDL A;  2E0A A;  4GQT A;  4MPN A;  2XCM A;  5GGZ A;  2WEP A;  4HYP A;  4YKZ A;  4L94 A;  3Q5J A;  4WUC A;  2HCH A;  2XX5 A;  3ZXO A;  4FPP A;  1US7 A;  2YE2 A;  3O0I A;  4XC0 A;  1UYE A;  4WUD A;  1YES A;  4YKT A;  3G75 A;  3GIG B;  2HG1 A;  4KSG A;  4FCP A;  3QTF A;  4W7T A;  2YK9 A;  2BRE A;  3HZ5 A;  1YT2 A;  2FYP A;  2YI5 A;  3BM9 A;  3PEJ A;  2IOR A;  4XE2 A;  1TIL A;  2ZKJ A;  4CWS A;  4XTJ A;  2GQP A;  1GKZ A;  2FWZ A;  4YKR A;  2HKJ A;  2QG2 A;  4HZ0 A;  4E01 A;  4XD8 A;  4L90 A;  3GIG A;  4MB9 A;  5M4E A;  1AMW A;  1QZR A;  4ASA A;  4MPE A;  3B24 A;  1B63 A;  3HHU A;  2XJX A;  3A0W A;  4YKQ A;  5M4H A;  3HEK A;  3BMY A;  3ZM7 A;  3JZ3 A;  4U93 A;  4HY1 A;  2YE8 A;  1OSF A;  3RLQ A;  2AKP A;  5CPH A;  5BOD A;  2XAB A;  2JKI A;  4AWP A;  5M4M A;  3VAD A;  3OPD A;  1PVG A;  1TBW A;  3R91 A;  5J6A A;  4AWO A;  4NH7 A;  4QPK A;  2BYH A;  2YKI A;  2WI2 A;  3O2F A;  3VHD A;  5D6Q A;  4BIZ A;  1Z5B A;  4R3M A;  2YGF A;  1GJV A;  2CG9 A;  3B27 A;  4O09 A;  3H4L A;  5F3K A;  4BAE A;  1ZXM A;  2YI7 A;  3OMU A;  4O07 A;  3U2D A;  5FND A;  2WI1 A;  3OWD A;  4V25 A;  1Z59 A;  1S16 A;  1NHI A;  1MX0 A;  3O6O A;  5M4N A;  2WI6 A;  4FCR A;  2XJJ A;  2YE6 A;  4JAV A;  4EM7 A;  2WI4 A;  4EEH A;  5IN9 A;  4MBC A;  4XIP A;  3A0Z A;  2YEC A;  4GFN A;  2YJX A;  4O05 A;  2YEB A;  4KFG A;  5L3J A;  2YGA A;  4E00 A;  5CTW A;  1YC1 A;  4KTN A;  5J71 A;  3GIE A;  1B62 A;  5M4K A;  3RKZ A;  1I58 A;  3CRK A;  2YK2 A;  2WI7 A;  3CGZ A;  2YKC A;  1UY7 A;  3LPS A;  2IOP A;  2K5B A;  4CE1 A;  4CWT A;  3RLR A;  4CWQ A;  3WQ9 A;  2IWS A;  3EHG A;  4ZKI A;  5FWK A;  1TH8 A;  2VCJ A;  1Y8P A;  2BT0 A;  3SL2 A;  2Q8I A;  2BSM A;  1A4H A;  3H80 A;  4PU9 A;  3A0X A;  3TZ4 A;  1U2O A;  3OWB A;  4MPC A;  1Y8N A;  4O0B A;  2C2A A;  3K97 A;  4BQJ A;  5D7D A;  3PEH A;  1NHH A;  2O1U A;  4HXZ A;  4CWN A;  2QF6 A;  3C11 A;  2YE4 A; 
#chains in the Genus database with same CATH topology
 4AS9 A;  4LWE A;  1JM6 A;  1YT1 A;  1YSZ A;  2CCT A;  1YET A;  4L8Z A;  3EHJ A;  1ZXN A;  1Y4U A;  1YSR A;  2XJG A;  2ZBK B;  5CTU A;  4I3H A;  4HY6 A;  4P8O A;  3T0H A;  4ZVI A;  4H7Q A;  2Q8F A;  3TZ5 A;  3T10 A;  1YC3 A;  4HYM A;  2XD6 A;  4E02 A;  1EA6 A;  4EGK A;  2CGF A;  4YKU A;  3RLP A;  2H8M A;  2CH4 A;  2O1W A;  4LWF A;  1ZWH A;  4BQG A;  2VCI A;  1UY9 A;  3CGY A;  4URN A;  3R4M A;  1R62 A;  4LWI A;  4NH9 A;  3U2K A;  4MP7 A;  4URM A;  4L91 A;  4E72 A;  4LPB A;  1IXM A;  3Q5L A;  1AM1 A;  1TC0 A;  3GIF A;  3U67 A;  2YEA A;  2YKE A;  4U7N A;  4URO A;  4NH8 A;  4XKO A;  4H85 A;  1BKN A;  4KQV A;  5IDJ A;  4FMT A;  2BU5 A;  4XKA A;  4XDM A;  4YKX A;  1AJ6 A;  2YEI A;  1THN A;  4MP2 A;  5IDM A;  3R4O A;  4V26 A;  2XDU A;  1BYQ A;  2QG0 A;  2WI5 A;  2YE5 A;  4PRX A;  1UYI A;  2YI0 A;  3G7E A;  2XHX A;  3EHH A;  4DZY A;  3IED A;  3HYZ A;  2YEF A;  2XDK A;  3R92 A;  3K98 A;  3TZ0 A;  4JQL A;  3TUH A;  1B3Q A;  1YER A;  2Q8H A;  1GKX A;  2XX4 A;  1UYC A;  1UYM A;  1UYK A;  5FNC A;  4Q20 A;  1Z5A A;  2YI6 A;  3MNR P;  1ZW9 A;  2ZDY A;  2YE3 A;  5CF0 A;  2EXL A;  3A0R A;  5D7R A;  4GEE A;  1BGQ A;  1UYF A;  4GCZ A;  4EFU A;  4ASG A;  4R1F A;  1Y8O A;  5D6P A;  5BOC A;  4K4O A;  3EKO A;  5CTX A;  3B25 A;  5F5R A;  3TTZ A;  1MU5 A;  1S14 A;  2YKJ A;  2H55 A;  4BIU A;  2IWU A;  3KE6 A;  1EI1 A;  2YJW A;  4CWO A;  3G7B A;  1UYD A;  4XIR A;  2C1I A;  3R4N A;  4ASF A;  1AH8 A;  1I5C A;  1QYE A;  3A0Y A;  2IWX A;  3INW A;  3S5T A;  4P7A A;  3EKR A;  4CWF A;  3ZXQ A;  2FXS A;  2XDX A;  4JAU A;  4EFT A;  3T2S A;  2QFO A;  2VW5 A;  2BYI A;  3TZ2 A;  2XK2 A;  2BU7 A;  2CCS A;  2XDS A;  4QPJ A;  1UY6 A;  3QDD A;  3CRL A;  3T1K A;  3D0B A;  4JAS A;  4H81 A;  2C1G A;  4HXW A;  2YEJ A;  4U7O A;  4URL A;  3LNU A;  1BXD A;  2WI3 A;  2CCU A;  3OW6 A;  4PRV A;  4XCJ A;  4CE3 A;  2WEQ A;  2YEE A;  3DGE A;  3HZ1 A;  1ID0 A;  4GGL A;  2YED A;  3D2R A;  3FV5 A;  2UWD A;  4KP4 A;  1I5D A;  4BXI A;  3LMM A;  4LWH A;  1TID A;  5JEN A;  4O04 A;  2BZ5 A;  2VWC A;  1UYG A;  2BRC A;  1L0O A;  3K99 A;  4WUB A;  2Q2E B;  3VHA A;  4LP0 A;  4PL9 A;  4EGI A;  1H7S A;  3K60 A;  4FCQ A;  1KZN A;  2ESA A;  3Q5K A;  4MOT A;  1I59 A;  3B28 A;  1UYH A;  1YT0 A;  4B6C A;  4XCL A;  4R3A A;  2YE7 A;  4GT8 A;  2BTZ A;  5D7C A;  4AWQ A;  4XIQ A;  2IOQ A;  3R4P A;  2FWY A;  2Q8G A;  4KSH A;  4LWG A;  4EMV A;  1I5A A;  2BU2 A;  1YC4 A;  5FNF A;  3CWV A;  2FTK A;  3FT5 A;  2XHT A;  3B26 A;  3NMQ A;  1KIJ A;  5CTY A;  3ZKD A;  2JJC A;  1YS3 A;  2XHR A;  1TC6 A;  2YGE A;  2ZDX A;  2BU6 A;  4CWP A;  3EHF A;  3WHA A;  2GFD A;  1U0Z A;  1AH6 A;  2YKB A;  1UYL A;  1QY8 A;  1Z5C A;  4EGH A;  2XX2 A;  1F51 A;  4I5S A;  4CE2 A;  1Y4S A;  3FT8 A;  4DUH A;  4XIT A;  4YKW A;  5M4P A;  5C93 A;  3T0Z A;  1H7U A;  3ZKB A;  1UY8 A;  4ASB A;  4YKY A;  3A0T A;  2O1V A;  3CYG A;  4B7P A;  4X9L A;  4CWR A;  4XKK A;  2PNR A;  3C0E A;  1I5B A;  1NHJ A;  2BU8 A;  3VHC A;  2YEH A;  2YE9 A;  3D36 A;  3INX A;  3HYY A;  4HZ5 A;  2YEG A;  4L93 A;  2WER A;  2XDL A;  2E0A A;  4GQT A;  4MPN A;  2XCM A;  5GGZ A;  2WEP A;  4HYP A;  4YKZ A;  4L94 A;  3Q5J A;  4WUC A;  2HCH A;  2XX5 A;  3ZXO A;  4FPP A;  1US7 A;  2YE2 A;  3O0I A;  4XC0 A;  1UYE A;  4WUD A;  1YES A;  4YKT A;  3G75 A;  3GIG B;  2HG1 A;  4KSG A;  4FCP A;  3QTF A;  4W7T A;  2YK9 A;  2BRE A;  3HZ5 A;  1YT2 A;  2FYP A;  2YI5 A;  3BM9 A;  3PEJ A;  2IOR A;  4XE2 A;  1TIL A;  2ZKJ A;  4CWS A;  4XTJ A;  2GQP A;  1GKZ A;  2FWZ A;  4YKR A;  2HKJ A;  2QG2 A;  4HZ0 A;  4E01 A;  4XD8 A;  4L90 A;  3GIG A;  4MB9 A;  5M4E A;  1AMW A;  1QZR A;  4ASA A;  4MPE A;  3B24 A;  1B63 A;  3HHU A;  2XJX A;  3A0W A;  4YKQ A;  5M4H A;  3HEK A;  3BMY A;  3ZM7 A;  3JZ3 A;  4U93 A;  4HY1 A;  2YE8 A;  1OSF A;  3RLQ A;  2AKP A;  5CPH A;  5BOD A;  2XAB A;  2JKI A;  4AWP A;  5M4M A;  3VAD A;  3OPD A;  1PVG A;  1TBW A;  3R91 A;  5J6A A;  4AWO A;  4NH7 A;  4QPK A;  2BYH A;  2YKI A;  2WI2 A;  3O2F A;  3VHD A;  5D6Q A;  4BIZ A;  1Z5B A;  4R3M A;  2YGF A;  1GJV A;  2CG9 A;  3B27 A;  4O09 A;  3H4L A;  5F3K A;  4BAE A;  1ZXM A;  2YI7 A;  3OMU A;  4O07 A;  3U2D A;  5FND A;  2WI1 A;  3OWD A;  4V25 A;  1Z59 A;  1S16 A;  1NHI A;  2HHI A;  1MX0 A;  3O6O A;  5M4N A;  2WI6 A;  4FCR A;  2XJJ A;  2YE6 A;  4JAV A;  4EM7 A;  2WI4 A;  4EEH A;  5IN9 A;  4MBC A;  4XIP A;  3A0Z A;  2YEC A;  4GFN A;  2YJX A;  4O05 A;  2YEB A;  4KFG A;  5L3J A;  2YGA A;  4E00 A;  5CTW A;  1YC1 A;  4KTN A;  5J71 A;  3GIE A;  1B62 A;  5M4K A;  3RKZ A;  1I58 A;  3CRK A;  2YK2 A;  2WI7 A;  3CGZ A;  2YKC A;  1UY7 A;  3LPS A;  2IOP A;  2K5B A;  4CE1 A;  4CWT A;  3RLR A;  4CWQ A;  3WQ9 A;  2IWS A;  3EHG A;  4ZKI A;  5FWK A;  1TH8 A;  2VCJ A;  1Y8P A;  2BT0 A;  3SL2 A;  2Q8I A;  2BSM A;  1A4H A;  3H80 A;  4PU9 A;  3A0X A;  3TZ4 A;  1U2O A;  3OWB A;  4MPC A;  1Y8N A;  4O0B A;  2C2A A;  3K97 A;  4BQJ A;  5D7D A;  3PEH A;  1NHH A;  2O1U A;  4HXZ A;  4CWN A;  2QF6 A;  3C11 A;  2YE4 A; 
#chains in the Genus database with same CATH homology
 4AS9 A;  4LWE A;  1JM6 A;  1YT1 A;  1YSZ A;  2CCT A;  1YET A;  4L8Z A;  3EHJ A;  1ZXN A;  1Y4U A;  1YSR A;  2XJG A;  2ZBK B;  5CTU A;  4I3H A;  4HY6 A;  4P8O A;  3T0H A;  4ZVI A;  4H7Q A;  2Q8F A;  3TZ5 A;  3T10 A;  1YC3 A;  4HYM A;  2XD6 A;  4E02 A;  1EA6 A;  4EGK A;  2CGF A;  4YKU A;  3RLP A;  2H8M A;  2CH4 A;  2O1W A;  4LWF A;  1ZWH A;  4BQG A;  2VCI A;  1UY9 A;  3CGY A;  4URN A;  3R4M A;  1R62 A;  4LWI A;  4NH9 A;  3U2K A;  4MP7 A;  4URM A;  4L91 A;  4LPB A;  3Q5L A;  1AM1 A;  1TC0 A;  3GIF A;  3U67 A;  2YEA A;  2YKE A;  4U7N A;  4URO A;  4NH8 A;  4XKO A;  4H85 A;  1BKN A;  4KQV A;  5IDJ A;  4FMT A;  2BU5 A;  4XKA A;  4XDM A;  4YKX A;  1AJ6 A;  2YEI A;  1THN A;  4MP2 A;  5IDM A;  3R4O A;  4V26 A;  2XDU A;  1BYQ A;  2QG0 A;  2WI5 A;  2YE5 A;  4PRX A;  1UYI A;  2YI0 A;  3G7E A;  2XHX A;  3EHH A;  4DZY A;  3IED A;  3HYZ A;  2YEF A;  2XDK A;  3R92 A;  3K98 A;  3TZ0 A;  4JQL A;  3TUH A;  1B3Q A;  1YER A;  2Q8H A;  1GKX A;  2XX4 A;  1UYC A;  1UYM A;  1UYK A;  5FNC A;  4Q20 A;  1Z5A A;  2YI6 A;  3MNR P;  1ZW9 A;  2ZDY A;  2YE3 A;  5CF0 A;  2EXL A;  3A0R A;  5D7R A;  4GEE A;  1BGQ A;  1UYF A;  4GCZ A;  4EFU A;  4ASG A;  4R1F A;  1Y8O A;  5D6P A;  5BOC A;  4K4O A;  3EKO A;  5CTX A;  3B25 A;  5F5R A;  3TTZ A;  1MU5 A;  1S14 A;  2YKJ A;  2H55 A;  4BIU A;  2IWU A;  3KE6 A;  1EI1 A;  2YJW A;  4CWO A;  3G7B A;  1UYD A;  4XIR A;  3R4N A;  4ASF A;  1AH8 A;  1I5C A;  1QYE A;  3A0Y A;  2IWX A;  3INW A;  4P7A A;  3EKR A;  4CWF A;  3ZXQ A;  2FXS A;  2XDX A;  4JAU A;  4EFT A;  3T2S A;  2QFO A;  2VW5 A;  2BYI A;  3TZ2 A;  2XK2 A;  2BU7 A;  2CCS A;  2XDS A;  4QPJ A;  1UY6 A;  3QDD A;  3CRL A;  3T1K A;  3D0B A;  4JAS A;  4H81 A;  4HXW A;  2YEJ A;  4U7O A;  4URL A;  3LNU A;  1BXD A;  2WI3 A;  2CCU A;  3OW6 A;  4PRV A;  4XCJ A;  4CE3 A;  2WEQ A;  2YEE A;  3DGE A;  3HZ1 A;  1ID0 A;  4GGL A;  2YED A;  3D2R A;  3FV5 A;  2UWD A;  4KP4 A;  1I5D A;  4BXI A;  4LWH A;  1TID A;  4O04 A;  2BZ5 A;  2VWC A;  1UYG A;  2BRC A;  1L0O A;  3K99 A;  4WUB A;  2Q2E B;  3VHA A;  4LP0 A;  4PL9 A;  4EGI A;  1H7S A;  3K60 A;  4FCQ A;  1KZN A;  2ESA A;  3Q5K A;  4MOT A;  1I59 A;  3B28 A;  1UYH A;  1YT0 A;  4B6C A;  4XCL A;  4R3A A;  2YE7 A;  4GT8 A;  2BTZ A;  5D7C A;  4AWQ A;  4XIQ A;  2IOQ A;  3R4P A;  2FWY A;  2Q8G A;  4KSH A;  4LWG A;  4EMV A;  1I5A A;  2BU2 A;  1YC4 A;  5FNF A;  3CWV A;  3FT5 A;  2XHT A;  3B26 A;  3NMQ A;  1KIJ A;  5CTY A;  3ZKD A;  2JJC A;  1YS3 A;  2XHR A;  1TC6 A;  2YGE A;  2ZDX A;  2BU6 A;  4CWP A;  3EHF A;  3WHA A;  2GFD A;  1U0Z A;  1AH6 A;  2YKB A;  1UYL A;  1QY8 A;  1Z5C A;  4EGH A;  2XX2 A;  4I5S A;  4CE2 A;  1Y4S A;  3FT8 A;  4DUH A;  4XIT A;  4YKW A;  5M4P A;  5C93 A;  3T0Z A;  1H7U A;  3ZKB A;  1UY8 A;  4ASB A;  4YKY A;  3A0T A;  2O1V A;  4B7P A;  4X9L A;  4CWR A;  4XKK A;  2PNR A;  3C0E A;  1I5B A;  1NHJ A;  2BU8 A;  3VHC A;  2YEH A;  2YE9 A;  3D36 A;  3INX A;  3HYY A;  4HZ5 A;  2YEG A;  4L93 A;  2WER A;  2XDL A;  2E0A A;  4GQT A;  4MPN A;  2XCM A;  5GGZ A;  2WEP A;  4HYP A;  4YKZ A;  4L94 A;  3Q5J A;  4WUC A;  2HCH A;  2XX5 A;  3ZXO A;  4FPP A;  1US7 A;  2YE2 A;  3O0I A;  4XC0 A;  1UYE A;  4WUD A;  1YES A;  4YKT A;  3G75 A;  3GIG B;  2HG1 A;  4KSG A;  4FCP A;  3QTF A;  4W7T A;  2YK9 A;  2BRE A;  3HZ5 A;  1YT2 A;  2FYP A;  2YI5 A;  3BM9 A;  3PEJ A;  2IOR A;  4XE2 A;  1TIL A;  2ZKJ A;  4CWS A;  4XTJ A;  2GQP A;  1GKZ A;  2FWZ A;  4YKR A;  2HKJ A;  2QG2 A;  4HZ0 A;  4E01 A;  4XD8 A;  4L90 A;  3GIG A;  4MB9 A;  5M4E A;  1AMW A;  1QZR A;  4ASA A;  4MPE A;  3B24 A;  1B63 A;  3HHU A;  2XJX A;  3A0W A;  4YKQ A;  5M4H A;  3HEK A;  3BMY A;  3ZM7 A;  3JZ3 A;  4U93 A;  4HY1 A;  2YE8 A;  1OSF A;  3RLQ A;  2AKP A;  5CPH A;  5BOD A;  2XAB A;  2JKI A;  4AWP A;  5M4M A;  3VAD A;  3OPD A;  1PVG A;  1TBW A;  3R91 A;  5J6A A;  4AWO A;  4NH7 A;  4QPK A;  2BYH A;  2YKI A;  2WI2 A;  3O2F A;  3VHD A;  5D6Q A;  4BIZ A;  1Z5B A;  4R3M A;  2YGF A;  1GJV A;  2CG9 A;  3B27 A;  4O09 A;  3H4L A;  5F3K A;  4BAE A;  1ZXM A;  2YI7 A;  3OMU A;  4O07 A;  3U2D A;  5FND A;  2WI1 A;  3OWD A;  4V25 A;  1Z59 A;  1S16 A;  1NHI A;  1MX0 A;  3O6O A;  5M4N A;  2WI6 A;  4FCR A;  2XJJ A;  2YE6 A;  4JAV A;  4EM7 A;  2WI4 A;  4EEH A;  5IN9 A;  4MBC A;  4XIP A;  3A0Z A;  2YEC A;  4GFN A;  2YJX A;  4O05 A;  2YEB A;  4KFG A;  5L3J A;  2YGA A;  4E00 A;  5CTW A;  1YC1 A;  4KTN A;  5J71 A;  3GIE A;  1B62 A;  5M4K A;  3RKZ A;  1I58 A;  3CRK A;  2YK2 A;  2WI7 A;  3CGZ A;  2YKC A;  1UY7 A;  3LPS A;  2IOP A;  2K5B A;  4CE1 A;  4CWT A;  3RLR A;  4CWQ A;  3WQ9 A;  2IWS A;  3EHG A;  4ZKI A;  5FWK A;  1TH8 A;  2VCJ A;  1Y8P A;  2BT0 A;  3SL2 A;  2Q8I A;  2BSM A;  1A4H A;  3H80 A;  4PU9 A;  3A0X A;  3TZ4 A;  1U2O A;  3OWB A;  4MPC A;  1Y8N A;  4O0B A;  2C2A A;  3K97 A;  4BQJ A;  5D7D A;  3PEH A;  1NHH A;  2O1U A;  4HXZ A;  4CWN A;  2QF6 A;  3C11 A;  2YE4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2VCIA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations