The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
95
|
sequence length |
379
|
structure length |
368
|
Chain Sequence |
SQTVRVDIEKLDNLMDLMGELVIARSRILETLKKYNIKELDESLSHLSRITLDLQNVVMKIRMVPISFVFNRFPRMVRDLAKKMNKEVNFIMRGEDTELDRTFVEEIGEPLLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRKAIEKGLIDESKAATLSDQEILNFLFVPGFSGVGMDVVKNVVESLNGSMGIESEKDKGTKVTIRLPLTLAIICALLVKVNNLVYAIPIANIDTILSISKEDIQRVQDRDVIVIRGEVIPVYRLWEVLQIEHKEELEEMEAVIVRVGNRKYGIVVDDLLGQDDIVIKSLGKVFSEVKEFSGAAILGDGSIALIINVSGIV
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure of CheA, a signal-transducing histidine kinase.
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Thermotoga maritima
|
| molecule keywords |
PROTEIN (CHEMOTAXIS PROTEIN CHEA)
|
| total genus |
95
|
| structure length |
368
|
| sequence length |
379
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.7.13.3: Histidine kinase. |
| pdb deposition date | 1998-12-14 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01584 | CheW | CheW-like domain |
| A | PF02518 | HATPase_c | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
| A | PF02895 | H-kinase_dim | Signal transducing histidine kinase, homodimeric domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Helix Hairpins | Histidine kinase CheA-like, homodimeric domain | ||
| Mainly Beta | Roll | SH3 type barrels. | SH3 Domains | ||
| Mainly Beta | Beta Barrel | OB fold (Dihydrolipoamide Acetyltransferase, E2P) | CheA-289, Domain 4 | ||
| Alpha Beta | 2-Layer Sandwich | Heat Shock Protein 90 | Histidine kinase-like ATPase, C-terminal domain |
