The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
82
|
sequence length |
606
|
structure length |
581
|
Chain Sequence |
KKQKSISVAEFFEKNRQILGFDSAPRSLITTVKEAVDNALDACEEAGILPDILVQVERTGPDYVTVIIEDNGPGIVREQIPKVFAKLLYGFHALKSRGQQGIGISAAVLYAQMTAGRHTKILSKTSPTAPAHYYELMINTSTNEPDILVDEVRDWFRPHGTQIELEMRAAYVKGRRQSIYEYLKATAIVNPHARITLIDPDGNEEVFERATDKMPEPAEEILPHPEGIELGTLMKMLHYTEPFLRYSFCKLLTAEEICKAAGLDPEIDPHALGRHEARKLIEAFEKVKIMAPPTDCLSPIGEDLIYRGLEKETTVDFIATSTRKPAVYSGNPFVVEVGMAYGGNLPKEEKISIMRFANRVPLLYQQGGCVTTHAVEDIKWKQYGLNQPGGGIPVGPVILLIHVASINVPFTSESKDAIADIPVIKEEIDLAIKEVARKLKHYLSKQSNLKKRREKEIIITKVLPKLAAKVAHVLEKDVPDINPVVAKIMGNLLVHRVIKNNGDGTVDVAIKVKNAYSFRVHEMLPCKVKPEPKVVTMGNDYDYVWDISASAGSSKVLSYKIESASEEELQKLPQLIVTGAK
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI
pubmed doi rcsb |
molecule tags |
Isomerase
|
source organism |
Methanosarcina mazei
|
molecule keywords |
Type II DNA topoisomerase VI subunit A
|
total genus |
82
|
structure length |
581
|
sequence length |
606
|
ec nomenclature |
ec
5.99.1.3: Transferred entry: 5.6.2.3. |
pdb deposition date | 2007-05-28 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
B | PF02518 | HATPase_c | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
B | PF09239 | Topo-VIb_trans | Topoisomerase VI B subunit, transducer |
B | PF18000 | Top6b_C | Type 2 DNA topoisomerase 6 subunit B C-terminal domain |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Mainly Alpha | Orthogonal Bundle | Helicase, Ruva Protein; domain 3 | Helicase, Ruva Protein; domain 3 | ||
Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Arc Repressor Mutant, subunit A | ||
Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
Alpha Beta | 2-Layer Sandwich | Ribosomal Protein S5; domain 2 | Ribosomal Protein S5; domain 2 | ||
Alpha Beta | 2-Layer Sandwich | Heat Shock Protein 90 | Histidine kinase-like ATPase, C-terminal domain |