1IS2 | Genus

Total Genus 255

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	255
sequence length	655
structure length	637
Chain Sequence	MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKNSVHRGHPEPLDLHLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Oxidoreductase
source organism	Rattus norvegicus
publication title	Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase. pubmed rcsb
molecule keywords	acyl-CoA oxidase
total genus	255
structure length	637
sequence length	655
chains with identical sequence	B
ec nomenclature	ec 1.3.3.6: Acyl-CoA oxidase.
pdb deposition date	2001-11-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01756	ACOX	Acyl-CoA oxidase
A	PF02770	Acyl-CoA_dh_M	Acyl-CoA dehydrogenase, middle domain
A	PF14749	Acyl-CoA_ox_N	Acyl-coenzyme A oxidase N-terminal

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A; domain 1	Acyl-CoA dehydrogenase/oxidase, N-terminal domain	1is2A01
1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A, domain 3	1is2A03
1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A, domain 3	1is2A04
2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A; domain 2	Butyryl-CoA Dehydrogenase, subunit A, domain 2	1is2A02

3M9VA 3RKHA 3SCEA 3AFFA 3GQTA 2YYKA 4IV6A 2IX6A 2C0UA 1FS8A 3SXQA 3X0YA 2Z1QA 3BNHA 1EGCA 2ZO5A 2JBTA 2RDZA 4ZXVA 3MPJA 4L1FA 2DVLA 2JIFA 2YYGA 3OWMA 2PG0A 1FS7A 2VR0A 2REHA 3AFEA 3D9EA 2OR0A 4NXLA 3B96A 4M9AA 3NF4A 4O5MA 2JBSA 2A1TA 3II9A 1BUCA 1W07A 3UBRA 3PFDA 4DOYA 3BNGA 3F29A 5K3IA 3P4TA 4N5FA 1RX0A 4L38A 3LG1A 3R7KA 1UKWA 1SIRA 3D9DA 2YYMA 2ZAFA 4JEKA 4L3XA 4Q5CA 2DDHA 4OO2A 2EBAA 3FCJA 3D9FA 1UDYA 4G5EA 3MKHA 2J7AA 2R0MA 4L3YA 3MDEA 5K3HA 3BNJA 1SIQA 4KCFA 2FONA 3BNFA 3OWAA 3L1TA 3HWCA 2WBIA 3X0XA 4XVXA 1GU6A 3MXLA 1EGDA 1OAHA 3GM6A 1QDBA 1EGEA 4IRNA 4WJYA 3TTBA 3TORA 2E80A 2IX5A 3FO3A 1JQIA 4KTOA 4U83A 4RM7A 1U8VA 2YYLA 2R0NA 3UU9A 2CX9A 2YYJA 3S7WA 4HR3A 3MMOA 3GNCA 2OT4A 4L3ZA 2RFQA 4X28C 3SWOA 2RF7A 4Q5BA 3SF6A 3OIBA 3D6BA 3MDDA 3D9GA 1T9GA 4W9UA 1IVHA 4Q4UA 2E81A 2UXWA 2YYIA 5K3JA 5K3GA 3MPIA 3EONA 2C12A 1WS9A 4Q17A 1FS9A 3EOMA 4Q1OA 4ZYJA 4Q0TA 2D29A 2VIGA 3D1IA 2JBRA 1IS2A 4P13A 1R2JA 3LGQA 4X28A
chains in the Genus database with same CATH superfamily

3M9VA 1X91A 3RKHA 3SCEA 3AFFA 3GQTA 2YYKA 5B6BA 4AI6A 4IV6A 2IX6A 2C0UA 1FS8A 2EC5A 5M4NA 3VKGA 3SXQA 3X0YA 2Z1QA 3BNHA 4KS9A 3Q23A 1XG2B 5EZ3A 1EGCA 2ZO5A 2JBTA 2BU2A 4MP7A 1K93A 2RDZA 4MP2A 4FF2A 4ZXVA 1XFUA 2ZDYA 3MPJA 4L1FA 1K90A 3N0RA 4KSFA 5B5VA 5BRMA 5M4MA 5M4KA 3Q22A 2LFWA 1Y8OA 4JIZA 4H7QA 2DVLA 2JIFA 2YYGA 3OWMA 2PG0A 1FS7A 4H85A 2VR0A 2XQRB 1S26A 2REHA 4QICA 4HKSA 3AFEA 4E02A 4AKIA 1PK0A 3D9EA 2GBBA 2OR0A 3D2RA 4NXLA 3B96A 4M9AA 3NF4A 2Q8GA 4O5MA 3VADA 3C3LA 2JBSA 2BTZA 4HKRA 2A1TA 3II9A 2Q8IA 4DZYA 2CJ5A 2QR4A 1BUCA 4V25A 2R03A 1W07A 3UBRA 3PFDA 4DOYA 3BNGA 3F29A 5K3IA 2CJ4A 2CJ6A 3P4TA 4N5FA 1RX0A 4L38A 2HJNA 3LG1A 3R7KA 1UKWA 1SIRA 3KMLA 3D9DA 4E00A 1XFVA 3CRLA 1RP3A 1Y8PA 2ZKJA 2YYMA 2ZAFA 4JEKA 4L3XA 4Q5CA 2Q8FA 2DDHA 4F0XA 4OO2A 4FF3A 2EBAA 2OJQA 3FCJA 2EBFX 3D9FA 1R3BA 2CJ8A 1UDYA 1GKZA 4FF1A 4G5EA 4LQSB 2PO4A 3MKHA 4MPEA 2J7AA 1XFYA 2R0MA 4L3YA 3VKHA 3MDEA 2XS8A 2OEXA 4J1VA 2AO2A 5K3HA 2BU7A 2FP1A 2BU5A 3BNJA 1SIQA 4KCFA 2FONA 2E0AA 1Y0VA 3BNFA 3OWAA 4AKHA 4P79A 3L1TA 3HWCA 3Q24A 2WBIA 3X0XA 3TZ0A 1JM6A 4XVXA 1GU6A 3MXLA 1EGDA 1OAHA 1SC5A 3CRKA 1SK6A 1QDBA 3GM6A 1EGEA 4IRNA 1XFWA 4WJYA 3TTBA 3TZ4A 1GKXA 3TZ2A 2FP2A 3TORA 5GJVE 2E80A 4LQQB 2IX5A 4AKGA 2CJ7A 3FO3A 1JQIA 4KTOA 4U83A 4RM7A 1U8VA 2BU6A 2R05A 2YYLA 3X29A 4KSAA 2R0NA 3C46A 5B5WA 4G97A 3UU9A 1X8ZA 2CX9A 3C2PA 1XFZA 1PI1A 2YYJA 3S7WA 4HR3A 2AZEA 2R02A 1K8TA 3MMOA 3GNCA 1X90A 2OT4A 4L3ZA 2RFQA 3U33A 4X28C 2ZDXA 3SWOA 1GJVA 2RF7A 1Y8NA 4Q5BA 3TZ5A 4V26A 2OEVA 3SF6A 2BU8A 3OIBA 4MPCA 4H81A 1RJ1A 2PNRA 3D6BA 2F6LA 3MDDA 3Q0AA 1XFXA 4FZ4A 1LVCA 3D9GA 4FF4A 1T9GA 4W9UA 4JIOA 1IVHA 4Q4UA 2YGWA 2E81A 2UXWA 2YYIA 4E01A 5K3JA 5K3GA 3MPIA 5M4PA 3EONA 2C12A 3DJLA 1WS9A 4MPNA 4Q17A 1FS9A 3EOMA 4Q1OA 5BRKA 4ZYJA 5GJWE 2VF1A 4Q0TA 5J6AA 2D29A 2Q8HA 5J71A 2VIGA 3D1IA 2JBRA 1IS2A 4P13A 3CE2A 2EBHX 1R2JA 2XS1A 1RJ4A 3LGQA 4X28A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3M9V A;  3RKH A;  3SCE A;  3AFF A;  3GQT A;  2YYK A;  4IV6 A;  2IX6 A;  2C0U A;  1FS8 A;  3SXQ A;  3X0Y A;  2Z1Q A;  3BNH A;  1EGC A;  2ZO5 A;  2JBT A;  2RDZ A;  4ZXV A;  3MPJ A;  4L1F A;  2DVL A;  2JIF A;  2YYG A;  3OWM A;  2PG0 A;  1FS7 A;  2VR0 A;  2REH A;  3AFE A;  3D9E A;  2OR0 A;  4NXL A;  3B96 A;  4M9A A;  3NF4 A;  4O5M A;  2JBS A;  2A1T A;  3II9 A;  1BUC A;  1W07 A;  3UBR A;  3PFD A;  4DOY A;  3BNG A;  3F29 A;  5K3I A;  3P4T A;  4N5F A;  1RX0 A;  4L38 A;  3LG1 A;  3R7K A;  1UKW A;  1SIR A;  3D9D A;  2YYM A;  2ZAF A;  4JEK A;  4L3X A;  4Q5C A;  2DDH A;  4OO2 A;  2EBA A;  3FCJ A;  3D9F A;  1UDY A;  4G5E A;  3MKH A;  2J7A A;  2R0M A;  4L3Y A;  3MDE A;  5K3H A;  3BNJ A;  1SIQ A;  4KCF A;  2FON A;  3BNF A;  3OWA A;  3L1T A;  3HWC A;  2WBI A;  3X0X A;  4XVX A;  1GU6 A;  3MXL A;  1EGD A;  1OAH A;  3GM6 A;  1QDB A;  1EGE A;  4IRN A;  4WJY A;  3TTB A;  3TOR A;  2E80 A;  2IX5 A;  3FO3 A;  1JQI A;  4KTO A;  4U83 A;  4RM7 A;  1U8V A;  2YYL A;  2R0N A;  3UU9 A;  2CX9 A;  2YYJ A;  3S7W A;  4HR3 A;  3MMO A;  3GNC A;  2OT4 A;  4L3Z A;  2RFQ A;  4X28 C;  3SWO A;  2RF7 A;  4Q5B A;  3SF6 A;  3OIB A;  3D6B A;  3MDD A;  3D9G A;  1T9G A;  4W9U A;  1IVH A;  4Q4U A;  2E81 A;  2UXW A;  2YYI A;  5K3J A;  5K3G A;  3MPI A;  3EON A;  2C12 A;  1WS9 A;  4Q17 A;  1FS9 A;  3EOM A;  4Q1O A;  4ZYJ A;  4Q0T A;  2D29 A;  2VIG A;  3D1I A;  2JBR A;  1IS2 A;  4P13 A;  1R2J A;  3LGQ A;  4X28 A; 
#chains in the Genus database with same CATH topology
 3M9V A;  1X91 A;  3RKH A;  3SCE A;  3AFF A;  3GQT A;  2YYK A;  5B6B A;  4AI6 A;  4IV6 A;  2IX6 A;  2C0U A;  1FS8 A;  2EC5 A;  5M4N A;  3VKG A;  3SXQ A;  3X0Y A;  2Z1Q A;  3BNH A;  4KS9 A;  3Q23 A;  1XG2 B;  5EZ3 A;  1EGC A;  2ZO5 A;  2JBT A;  2BU2 A;  4MP7 A;  1K93 A;  2RDZ A;  4MP2 A;  4FF2 A;  4ZXV A;  1XFU A;  2ZDY A;  3MPJ A;  4L1F A;  1K90 A;  3N0R A;  4KSF A;  5B5V A;  5BRM A;  5M4M A;  5M4K A;  3Q22 A;  2LFW A;  1Y8O A;  4JIZ A;  4H7Q A;  2DVL A;  2JIF A;  2YYG A;  3OWM A;  2PG0 A;  1FS7 A;  4H85 A;  2VR0 A;  2XQR B;  1S26 A;  2REH A;  4QIC A;  4HKS A;  3AFE A;  4E02 A;  4AKI A;  1PK0 A;  3D9E A;  2GBB A;  2OR0 A;  3D2R A;  4NXL A;  3B96 A;  4M9A A;  3NF4 A;  2Q8G A;  4O5M A;  3VAD A;  3C3L A;  2JBS A;  2BTZ A;  4HKR A;  2A1T A;  3II9 A;  2Q8I A;  4DZY A;  2CJ5 A;  2QR4 A;  1BUC A;  4V25 A;  2R03 A;  1W07 A;  3UBR A;  3PFD A;  4DOY A;  3BNG A;  3F29 A;  5K3I A;  2CJ4 A;  2CJ6 A;  3P4T A;  4N5F A;  1RX0 A;  4L38 A;  2HJN A;  3LG1 A;  3R7K A;  1UKW A;  1SIR A;  3KML A;  3D9D A;  4E00 A;  1XFV A;  3CRL A;  1RP3 A;  1Y8P A;  2ZKJ A;  2YYM A;  2ZAF A;  4JEK A;  4L3X A;  4Q5C A;  2Q8F A;  2DDH A;  4F0X A;  4OO2 A;  4FF3 A;  2EBA A;  2OJQ A;  3FCJ A;  2EBF X;  3D9F A;  1R3B A;  2CJ8 A;  1UDY A;  1GKZ A;  4FF1 A;  4G5E A;  4LQS B;  2PO4 A;  3MKH A;  4MPE A;  2J7A A;  1XFY A;  2R0M A;  4L3Y A;  3VKH A;  3MDE A;  2XS8 A;  2OEX A;  4J1V A;  2AO2 A;  5K3H A;  2BU7 A;  2FP1 A;  2BU5 A;  3BNJ A;  1SIQ A;  4KCF A;  2FON A;  2E0A A;  1Y0V A;  3BNF A;  3OWA A;  4AKH A;  4P79 A;  3L1T A;  3HWC A;  3Q24 A;  2WBI A;  3X0X A;  3TZ0 A;  1JM6 A;  4XVX A;  1GU6 A;  3MXL A;  1EGD A;  1OAH A;  1SC5 A;  3CRK A;  1SK6 A;  1QDB A;  3GM6 A;  1EGE A;  4IRN A;  1XFW A;  4WJY A;  3TTB A;  3TZ4 A;  1GKX A;  3TZ2 A;  2FP2 A;  3TOR A;  5GJV E;  2E80 A;  4LQQ B;  2IX5 A;  4AKG A;  2CJ7 A;  3FO3 A;  1JQI A;  4KTO A;  4U83 A;  4RM7 A;  1U8V A;  2BU6 A;  2R05 A;  2YYL A;  3X29 A;  4KSA A;  2R0N A;  3C46 A;  5B5W A;  4G97 A;  3UU9 A;  1X8Z A;  2CX9 A;  3C2P A;  1XFZ A;  1PI1 A;  2YYJ A;  3S7W A;  4HR3 A;  2AZE A;  2R02 A;  1K8T A;  3MMO A;  3GNC A;  1X90 A;  2OT4 A;  4L3Z A;  2RFQ A;  3U33 A;  4X28 C;  2ZDX A;  3SWO A;  1GJV A;  2RF7 A;  1Y8N A;  4Q5B A;  3TZ5 A;  4V26 A;  2OEV A;  3SF6 A;  2BU8 A;  3OIB A;  4MPC A;  4H81 A;  1RJ1 A;  2PNR A;  3D6B A;  2F6L A;  3MDD A;  3Q0A A;  1XFX A;  4FZ4 A;  1LVC A;  3D9G A;  4FF4 A;  1T9G A;  4W9U A;  4JIO A;  1IVH A;  4Q4U A;  2YGW A;  2E81 A;  2UXW A;  2YYI A;  4E01 A;  5K3J A;  5K3G A;  3MPI A;  5M4P A;  3EON A;  2C12 A;  3DJL A;  1WS9 A;  4MPN A;  4Q17 A;  1FS9 A;  3EOM A;  4Q1O A;  5BRK A;  4ZYJ A;  5GJW E;  2VF1 A;  4Q0T A;  5J6A A;  2D29 A;  2Q8H A;  5J71 A;  2VIG A;  3D1I A;  2JBR A;  1IS2 A;  4P13 A;  3CE2 A;  2EBH X;  1R2J A;  2XS1 A;  1RJ4 A;  3LGQ A;  4X28 A; 
#chains in the Genus database with same CATH homology
 3M9V A;  3RKH A;  3SCE A;  3AFF A;  3GQT A;  2YYK A;  4IV6 A;  2IX6 A;  2C0U A;  1FS8 A;  3SXQ A;  3X0Y A;  2Z1Q A;  3BNH A;  1EGC A;  2ZO5 A;  2JBT A;  2RDZ A;  4ZXV A;  3MPJ A;  4L1F A;  2DVL A;  2JIF A;  2YYG A;  3OWM A;  2PG0 A;  1FS7 A;  2VR0 A;  2REH A;  3AFE A;  3D9E A;  2OR0 A;  4NXL A;  3B96 A;  4M9A A;  3NF4 A;  4O5M A;  2JBS A;  2A1T A;  3II9 A;  1BUC A;  1W07 A;  3UBR A;  3PFD A;  4DOY A;  3BNG A;  3F29 A;  5K3I A;  3P4T A;  4N5F A;  1RX0 A;  4L38 A;  3LG1 A;  3R7K A;  1UKW A;  1SIR A;  3D9D A;  2YYM A;  2ZAF A;  4JEK A;  4L3X A;  4Q5C A;  2DDH A;  4OO2 A;  2EBA A;  3FCJ A;  3D9F A;  1UDY A;  4G5E A;  3MKH A;  2J7A A;  2R0M A;  4L3Y A;  3MDE A;  5K3H A;  3BNJ A;  1SIQ A;  4KCF A;  2FON A;  3BNF A;  3OWA A;  3L1T A;  3HWC A;  2WBI A;  3X0X A;  4XVX A;  1GU6 A;  3MXL A;  1EGD A;  1OAH A;  3GM6 A;  1QDB A;  1EGE A;  4IRN A;  4WJY A;  3TTB A;  3TOR A;  2E80 A;  2IX5 A;  3FO3 A;  1JQI A;  4KTO A;  4U83 A;  4RM7 A;  1U8V A;  2YYL A;  2R0N A;  3UU9 A;  2CX9 A;  2YYJ A;  3S7W A;  4HR3 A;  3MMO A;  3GNC A;  2OT4 A;  4L3Z A;  2RFQ A;  4X28 C;  3SWO A;  2RF7 A;  4Q5B A;  3SF6 A;  3OIB A;  3D6B A;  3MDD A;  3D9G A;  1T9G A;  4W9U A;  1IVH A;  4Q4U A;  2E81 A;  2UXW A;  2YYI A;  5K3J A;  5K3G A;  3MPI A;  3EON A;  2C12 A;  1WS9 A;  4Q17 A;  1FS9 A;  3EOM A;  4Q1O A;  4ZYJ A;  4Q0T A;  2D29 A;  2VIG A;  3D1I A;  2JBR A;  1IS2 A;  4P13 A;  1R2J A;  3LGQ A;  4X28 A;

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similar chains in the Genus database (?% sequence similarity)

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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1IS2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations