2UXWA

Crystal structure of human very long chain acyl-coa dehydrogenase (acadvl)
Total Genus 213
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
213
sequence length
587
structure length
567
Chain Sequence
QSMSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Homo sapiens
publication title Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
rcsb
molecule keywords VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE
total genus 213
structure length 567
sequence length 587
ec nomenclature ec 1.3.8.9: Very-long-chain acyl-CoA dehydrogenase.
pdb deposition date 2007-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2uxwA02
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2uxwA04
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2uxwA01
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2uxwA03
4JEKA 1R2JA 3P4TA 4IRNA 1SIRA 2C12A 1RX0A 4W9UA 3NF4A 2PG0A 2E80A 4WJYA 4N5FA 2UXWA 1OAHA 1UKWA 2J7AA 2DVLA 1IVHA 2CX9A 1QDBA 3MMOA 3LG1A 3AFFA 4HR3A 3D1IA 4DOYA 3BNHA 2Z1QA 3BNJA 2R0MA 2OR0A 5K3HA 2YYMA 4P13A 2C0UA 4RM7A 3PFDA 4KCFA 3D9FA 4M9AA 2DDHA 3OWMA 3OWAA 4O5MA 4Q4UA 3AFEA 2ZAFA 3MKHA 3LGQA 2JBTA 3FO3A 3BNGA 2A1TA 3D9EA 2EBAA 2YYKA 3BNFA 3SF6A 3GM6A 3D9DA 1IS2A 2VIGA 2RFQA 2E81A 3OIBA 2YYJA 2WBIA 3GNCA 3D6BA 3MXLA 5K3GA 4X28C 5K3IA 3X0YA 2OT4A 4Q5CA 1T9GA 1WS9A 4L3ZA 3RKHA 3R7KA 3UU9A 1JQIA 2JBRA 2R0NA 3GQTA 3TTBA 4Q5BA 4Q1OA 4Q0TA 3F29A 1FS9A 1SIQA 4XVXA 4U83A 4L38A 3B96A 4NXLA 3MDDA 4L3YA 2IX5A 3SXQA 1W07A 3II9A 4ZXVA 3EOMA 4Q17A 2FONA 4L3XA 4L1FA 1FS7A 2JBSA 3SWOA 2IX6A 3S7WA 1EGDA 2JIFA 2VR0A 1GU6A 5K3JA 3HWCA 2YYLA 2REHA 1UDYA 3MDEA 3L1TA 1BUCA 2RF7A 3FCJA 2ZO5A 3TORA 1FS8A 4ZYJA 4IV6A 4G5EA 3SCEA 1EGCA 2YYGA 3MPJA 2D29A 2RDZA 3UBRA 1EGEA 3M9VA 3MPIA 3X0XA 4KTOA 1U8VA 4X28A 4OO2A 3D9GA 2YYIA 3EONA
chains in the Genus database with same CATH superfamily
4JEKA 4AKHA 1R2JA 1K93A 3P4TA 4IRNA 5BRKA 1RJ4A 1SIRA 2C12A 1RX0A 4W9UA 3N0RA 3NF4A 2PG0A 2E80A 4WJYA 4N5FA 2ZKJA 3KMLA 4DZYA 4MPNA 2UXWA 1OAHA 1UKWA 2J7AA 2DVLA 2VF1A 1IVHA 4V26A 5J71A 5J6AA 3C2PA 3VKGA 2CX9A 2CJ6A 2OJQA 1QDBA 1LVCA 4MP7A 3MMOA 3LG1A 2ZDXA 3C3LA 3AFFA 4HR3A 3D1IA 4DOYA 3BNHA 3X29A 3Q22A 1XFVA 2Z1QA 3BNJA 2R0MA 1Y8OA 2OR0A 5K3HA 2YYMA 2Q8HA 4P13A 2BU5A 2C0UA 4E01A 4RM7A 3PFDA 4KCFA 3TZ5A 3D9FA 2Q8GA 4M9AA 2BU6A 2DDHA 3OWMA 3OWAA 3TZ0A 4MP2A 2XS1A 1SK6A 4O5MA 4Q4UA 3AFEA 2GBBA 4JIZA 1X8ZA 2FP1A 1SC5A 1Y8PA 3CRKA 2ZAFA 2PNRA 5M4PA 3Q23A 3MKHA 2Q8IA 3LGQA 2JBTA 5BRMA 1R3BA 1XFWA 1JM6A 5B5WA 3FO3A 3D2RA 3BNGA 2AZEA 2A1TA 2PO4A 3D9EA 2EBAA 2OEXA 2YYKA 3BNFA 3SF6A 1XG2B 3GM6A 4G97A 4E00A 3D9DA 1IS2A 2EBFX 4KS9A 4E02A 5B6BA 2VIGA 5M4KA 2RFQA 4HKSA 1PK0A 3OIBA 2E81A 2YYJA 2WBIA 3VADA 5M4MA 3GNCA 3D6BA 2CJ8A 3MXLA 5K3GA 5B5VA 4X28C 1X91A 5K3IA 2OEVA 3X0YA 5GJVE 4FF2A 1S26A 2OT4A 1X90A 4Q5CA 1T9GA 4H85A 1WS9A 4L3ZA 4MPCA 2CJ4A 3RKHA 5EZ3A 3R7KA 4QICA 4J1VA 2LFWA 1JQIA 1RP3A 4KSFA 3UU9A 2BTZA 2JBRA 2R0NA 3GQTA 2CJ7A 3TTBA 4Q5BA 4Q1OA 4HKRA 4Q0TA 3F29A 1FS9A 1SIQA 4XVXA 2QR4A 2EC5A 4U83A 4FF4A 4FF3A 4L38A 3B96A 4NXLA 3MDDA 3Q0AA 2R03A 4L3YA 2IX5A 2BU7A 2R02A 1W07A 4KSAA 3SXQA 3II9A 4ZXVA 3EOMA 2E0AA 2XQRB 4JIOA 2YYIA 1Y0VA 2BU2A 2FONA 1GKZA 4L1FA 1XFXA 1FS7A 4L3XA 2JBSA 1GJVA 3SWOA 2IX6A 4FZ4A 2XS8A 2BU8A 4MPEA 1RJ1A 3S7WA 1EGDA 2JIFA 1GKXA 2VR0A 3CRLA 1GU6A 4FF1A 5GJWE 5K3JA 3HWCA 3TZ2A 2YYLA 2REHA 1UDYA 2Q8FA 4H81A 3MDEA 3L1TA 1XFZA 4P79A 1BUCA 2AO2A 2RF7A 3FCJA 3TZ4A 2ZO5A 1XFYA 4Q17A 4AKGA 1K8TA 3TORA 1FS8A 4H7QA 4ZYJA 1XFUA 2EBHX 3U33A 4IV6A 4G5EA 3SCEA 4AKIA 1EGCA 2YYGA 1K90A 4AI6A 4LQQB 3MPJA 2YGWA 2D29A 3Q24A 3DJLA 2F6LA 2RDZA 1Y8NA 1EGEA 3UBRA 3M9VA 3MPIA 2HJNA 3C46A 3CE2A 1PI1A 3X0XA 2R05A 2ZDYA 4KTOA 1U8VA 4LQSB 5M4NA 4X28A 4OO2A 3D9GA 4F0XA 3VKHA 2FP2A 4V25A 2CJ5A 3EONA
chains in the Genus database with same CATH topology
4JEKA 1R2JA 3P4TA 4IRNA 1SIRA 2C12A 1RX0A 4W9UA 3NF4A 2PG0A 2E80A 4WJYA 4N5FA 2UXWA 1OAHA 1UKWA 2J7AA 2DVLA 1IVHA 2CX9A 1QDBA 3MMOA 3LG1A 3AFFA 4HR3A 3D1IA 4DOYA 3BNHA 2Z1QA 3BNJA 2R0MA 2OR0A 5K3HA 2YYMA 4P13A 2C0UA 4RM7A 3PFDA 4KCFA 3D9FA 4M9AA 2DDHA 3OWMA 3OWAA 4O5MA 4Q4UA 3AFEA 2ZAFA 3MKHA 3LGQA 2JBTA 3FO3A 3BNGA 2A1TA 3D9EA 2EBAA 2YYKA 3BNFA 3SF6A 3GM6A 3D9DA 1IS2A 2VIGA 2RFQA 2E81A 3OIBA 2YYJA 2WBIA 3GNCA 3D6BA 3MXLA 5K3GA 4X28C 5K3IA 3X0YA 2OT4A 4Q5CA 1T9GA 1WS9A 4L3ZA 3RKHA 3R7KA 3UU9A 1JQIA 2JBRA 2R0NA 3GQTA 3TTBA 4Q5BA 4Q1OA 4Q0TA 3F29A 1FS9A 1SIQA 4XVXA 4U83A 4L38A 3B96A 4NXLA 3MDDA 4L3YA 2IX5A 3SXQA 1W07A 3II9A 4ZXVA 3EOMA 4Q17A 2FONA 4L3XA 4L1FA 1FS7A 2JBSA 3SWOA 2IX6A 3S7WA 1EGDA 2JIFA 2VR0A 1GU6A 5K3JA 3HWCA 2YYLA 2REHA 1UDYA 3MDEA 3L1TA 1BUCA 2RF7A 3FCJA 2ZO5A 3TORA 1FS8A 4ZYJA 4IV6A 4G5EA 3SCEA 1EGCA 2YYGA 3MPJA 2D29A 2RDZA 3UBRA 1EGEA 3M9VA 3MPIA 3X0XA 4KTOA 1U8VA 4X28A 4OO2A 3D9GA 2YYIA 3EONA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JEK A;  1R2J A;  3P4T A;  4IRN A;  1SIR A;  2C12 A;  1RX0 A;  4W9U A;  3NF4 A;  2PG0 A;  2E80 A;  4WJY A;  4N5F A;  2UXW A;  1OAH A;  1UKW A;  2J7A A;  2DVL A;  1IVH A;  2CX9 A;  1QDB A;  3MMO A;  3LG1 A;  3AFF A;  4HR3 A;  3D1I A;  4DOY A;  3BNH A;  2Z1Q A;  3BNJ A;  2R0M A;  2OR0 A;  5K3H A;  2YYM A;  4P13 A;  2C0U A;  4RM7 A;  3PFD A;  4KCF A;  3D9F A;  4M9A A;  2DDH A;  3OWM A;  3OWA A;  4O5M A;  4Q4U A;  3AFE A;  2ZAF A;  3MKH A;  3LGQ A;  2JBT A;  3FO3 A;  3BNG A;  2A1T A;  3D9E A;  2EBA A;  2YYK A;  3BNF A;  3SF6 A;  3GM6 A;  3D9D A;  1IS2 A;  2VIG A;  2RFQ A;  2E81 A;  3OIB A;  2YYJ A;  2WBI A;  3GNC A;  3D6B A;  3MXL A;  5K3G A;  4X28 C;  5K3I A;  3X0Y A;  2OT4 A;  4Q5C A;  1T9G A;  1WS9 A;  4L3Z A;  3RKH A;  3R7K A;  3UU9 A;  1JQI A;  2JBR A;  2R0N A;  3GQT A;  3TTB A;  4Q5B A;  4Q1O A;  4Q0T A;  3F29 A;  1FS9 A;  1SIQ A;  4XVX A;  4U83 A;  4L38 A;  3B96 A;  4NXL A;  3MDD A;  4L3Y A;  2IX5 A;  3SXQ A;  1W07 A;  3II9 A;  4ZXV A;  3EOM A;  4Q17 A;  2FON A;  4L3X A;  4L1F A;  1FS7 A;  2JBS A;  3SWO A;  2IX6 A;  3S7W A;  1EGD A;  2JIF A;  2VR0 A;  1GU6 A;  5K3J A;  3HWC A;  2YYL A;  2REH A;  1UDY A;  3MDE A;  3L1T A;  1BUC A;  2RF7 A;  3FCJ A;  2ZO5 A;  3TOR A;  1FS8 A;  4ZYJ A;  4IV6 A;  4G5E A;  3SCE A;  1EGC A;  2YYG A;  3MPJ A;  2D29 A;  2RDZ A;  3UBR A;  1EGE A;  3M9V A;  3MPI A;  3X0X A;  4KTO A;  1U8V A;  4X28 A;  4OO2 A;  3D9G A;  2YYI A;  3EON A; 
#chains in the Genus database with same CATH topology
 4JEK A;  4AKH A;  1R2J A;  1K93 A;  3P4T A;  4IRN A;  5BRK A;  1RJ4 A;  1SIR A;  2C12 A;  1RX0 A;  4W9U A;  3N0R A;  3NF4 A;  2PG0 A;  2E80 A;  4WJY A;  4N5F A;  2ZKJ A;  3KML A;  4DZY A;  4MPN A;  2UXW A;  1OAH A;  1UKW A;  2J7A A;  2DVL A;  2VF1 A;  1IVH A;  4V26 A;  5J71 A;  5J6A A;  3C2P A;  3VKG A;  2CX9 A;  2CJ6 A;  2OJQ A;  1QDB A;  1LVC A;  4MP7 A;  3MMO A;  3LG1 A;  2ZDX A;  3C3L A;  3AFF A;  4HR3 A;  3D1I A;  4DOY A;  3BNH A;  3X29 A;  3Q22 A;  1XFV A;  2Z1Q A;  3BNJ A;  2R0M A;  1Y8O A;  2OR0 A;  5K3H A;  2YYM A;  2Q8H A;  4P13 A;  2BU5 A;  2C0U A;  4E01 A;  4RM7 A;  3PFD A;  4KCF A;  3TZ5 A;  3D9F A;  2Q8G A;  4M9A A;  2BU6 A;  2DDH A;  3OWM A;  3OWA A;  3TZ0 A;  4MP2 A;  2XS1 A;  1SK6 A;  4O5M A;  4Q4U A;  3AFE A;  2GBB A;  4JIZ A;  1X8Z A;  2FP1 A;  1SC5 A;  1Y8P A;  3CRK A;  2ZAF A;  2PNR A;  5M4P A;  3Q23 A;  3MKH A;  2Q8I A;  3LGQ A;  2JBT A;  5BRM A;  1R3B A;  1XFW A;  1JM6 A;  5B5W A;  3FO3 A;  3D2R A;  3BNG A;  2AZE A;  2A1T A;  2PO4 A;  3D9E A;  2EBA A;  2OEX A;  2YYK A;  3BNF A;  3SF6 A;  1XG2 B;  3GM6 A;  4G97 A;  4E00 A;  3D9D A;  1IS2 A;  2EBF X;  4KS9 A;  4E02 A;  5B6B A;  2VIG A;  5M4K A;  2RFQ A;  4HKS A;  1PK0 A;  3OIB A;  2E81 A;  2YYJ A;  2WBI A;  3VAD A;  5M4M A;  3GNC A;  3D6B A;  2CJ8 A;  3MXL A;  5K3G A;  5B5V A;  4X28 C;  1X91 A;  5K3I A;  2OEV A;  3X0Y A;  5GJV E;  4FF2 A;  1S26 A;  2OT4 A;  1X90 A;  4Q5C A;  1T9G A;  4H85 A;  1WS9 A;  4L3Z A;  4MPC A;  2CJ4 A;  3RKH A;  5EZ3 A;  3R7K A;  4QIC A;  4J1V A;  2LFW A;  1JQI A;  1RP3 A;  4KSF A;  3UU9 A;  2BTZ A;  2JBR A;  2R0N A;  3GQT A;  2CJ7 A;  3TTB A;  4Q5B A;  4Q1O A;  4HKR A;  4Q0T A;  3F29 A;  1FS9 A;  1SIQ A;  4XVX A;  2QR4 A;  2EC5 A;  4U83 A;  4FF4 A;  4FF3 A;  4L38 A;  3B96 A;  4NXL A;  3MDD A;  3Q0A A;  2R03 A;  4L3Y A;  2IX5 A;  2BU7 A;  2R02 A;  1W07 A;  4KSA A;  3SXQ A;  3II9 A;  4ZXV A;  3EOM A;  2E0A A;  2XQR B;  4JIO A;  2YYI A;  1Y0V A;  2BU2 A;  2FON A;  1GKZ A;  4L1F A;  1XFX A;  1FS7 A;  4L3X A;  2JBS A;  1GJV A;  3SWO A;  2IX6 A;  4FZ4 A;  2XS8 A;  2BU8 A;  4MPE A;  1RJ1 A;  3S7W A;  1EGD A;  2JIF A;  1GKX A;  2VR0 A;  3CRL A;  1GU6 A;  4FF1 A;  5GJW E;  5K3J A;  3HWC A;  3TZ2 A;  2YYL A;  2REH A;  1UDY A;  2Q8F A;  4H81 A;  3MDE A;  3L1T A;  1XFZ A;  4P79 A;  1BUC A;  2AO2 A;  2RF7 A;  3FCJ A;  3TZ4 A;  2ZO5 A;  1XFY A;  4Q17 A;  4AKG A;  1K8T A;  3TOR A;  1FS8 A;  4H7Q A;  4ZYJ A;  1XFU A;  2EBH X;  3U33 A;  4IV6 A;  4G5E A;  3SCE A;  4AKI A;  1EGC A;  2YYG A;  1K90 A;  4AI6 A;  4LQQ B;  3MPJ A;  2YGW A;  2D29 A;  3Q24 A;  3DJL A;  2F6L A;  2RDZ A;  1Y8N A;  1EGE A;  3UBR A;  3M9V A;  3MPI A;  2HJN A;  3C46 A;  3CE2 A;  1PI1 A;  3X0X A;  2R05 A;  2ZDY A;  4KTO A;  1U8V A;  4LQS B;  5M4N A;  4X28 A;  4OO2 A;  3D9G A;  4F0X A;  3VKH A;  2FP2 A;  4V25 A;  2CJ5 A;  3EON A; 
#chains in the Genus database with same CATH homology
 4JEK A;  1R2J A;  3P4T A;  4IRN A;  1SIR A;  2C12 A;  1RX0 A;  4W9U A;  3NF4 A;  2PG0 A;  2E80 A;  4WJY A;  4N5F A;  2UXW A;  1OAH A;  1UKW A;  2J7A A;  2DVL A;  1IVH A;  2CX9 A;  1QDB A;  3MMO A;  3LG1 A;  3AFF A;  4HR3 A;  3D1I A;  4DOY A;  3BNH A;  2Z1Q A;  3BNJ A;  2R0M A;  2OR0 A;  5K3H A;  2YYM A;  4P13 A;  2C0U A;  4RM7 A;  3PFD A;  4KCF A;  3D9F A;  4M9A A;  2DDH A;  3OWM A;  3OWA A;  4O5M A;  4Q4U A;  3AFE A;  2ZAF A;  3MKH A;  3LGQ A;  2JBT A;  3FO3 A;  3BNG A;  2A1T A;  3D9E A;  2EBA A;  2YYK A;  3BNF A;  3SF6 A;  3GM6 A;  3D9D A;  1IS2 A;  2VIG A;  2RFQ A;  2E81 A;  3OIB A;  2YYJ A;  2WBI A;  3GNC A;  3D6B A;  3MXL A;  5K3G A;  4X28 C;  5K3I A;  3X0Y A;  2OT4 A;  4Q5C A;  1T9G A;  1WS9 A;  4L3Z A;  3RKH A;  3R7K A;  3UU9 A;  1JQI A;  2JBR A;  2R0N A;  3GQT A;  3TTB A;  4Q5B A;  4Q1O A;  4Q0T A;  3F29 A;  1FS9 A;  1SIQ A;  4XVX A;  4U83 A;  4L38 A;  3B96 A;  4NXL A;  3MDD A;  4L3Y A;  2IX5 A;  3SXQ A;  1W07 A;  3II9 A;  4ZXV A;  3EOM A;  4Q17 A;  2FON A;  4L3X A;  4L1F A;  1FS7 A;  2JBS A;  3SWO A;  2IX6 A;  3S7W A;  1EGD A;  2JIF A;  2VR0 A;  1GU6 A;  5K3J A;  3HWC A;  2YYL A;  2REH A;  1UDY A;  3MDE A;  3L1T A;  1BUC A;  2RF7 A;  3FCJ A;  2ZO5 A;  3TOR A;  1FS8 A;  4ZYJ A;  4IV6 A;  4G5E A;  3SCE A;  1EGC A;  2YYG A;  3MPJ A;  2D29 A;  2RDZ A;  3UBR A;  1EGE A;  3M9V A;  3MPI A;  3X0X A;  4KTO A;  1U8V A;  4X28 A;  4OO2 A;  3D9G A;  2YYI A;  3EON A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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