2UXW | Genus

Total Genus 213

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	213
sequence length	587
structure length	567
Chain Sequence	QSMSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxidoreductase
source organism	Homo sapiens
publication title	Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl) rcsb
molecule keywords	VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE
total genus	213
structure length	567
sequence length	587
ec nomenclature	ec 1.3.8.9: Very-long-chain acyl-CoA dehydrogenase.
pdb deposition date	2007-03-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00441	Acyl-CoA_dh_1	Acyl-CoA dehydrogenase, C-terminal domain
A	PF02770	Acyl-CoA_dh_M	Acyl-CoA dehydrogenase, middle domain
A	PF02771	Acyl-CoA_dh_N	Acyl-CoA dehydrogenase, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A; domain 1	Acyl-CoA dehydrogenase/oxidase, N-terminal domain	2uxwA02
1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A, domain 3	2uxwA04
1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A, domain 3	2uxwA01
2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A; domain 2	Butyryl-CoA Dehydrogenase, subunit A, domain 2	2uxwA03

4RM7A 3SCEA 3R7KA 2E81A 2A1TA 2C0UA 3SXQA 3P4TA 3D9DA 4IV6A 1JQIA 2JBTA 4X28C 5K3JA 4Q0TA 1EGEA 3EOMA 2ZAFA 3FO3A 3MDEA 4L38A 2YYIA 3D9EA 3S7WA 4OO2A 4IRNA 1FS8A 2YYKA 2REHA 2RDZA 2FONA 1WS9A 5K3IA 2D29A 3II9A 2YYMA 3MPJA 2YYGA 4N5FA 2DDHA 3M9VA 3AFFA 2ZO5A 4Q5BA 3B96A 3L1TA 3UU9A 3UBRA 4NXLA 1GU6A 2IX5A 3BNJA 4W9UA 1IS2A 2RFQA 3RKHA 4U83A 2YYJA 3X0YA 1EGDA 2JBRA 1UKWA 3X0XA 5K3GA 3LG1A 1BUCA 3MMOA 4ZYJA 4M9AA 2JIFA 3MPIA 1QDBA 3D6BA 1U8VA 3MDDA 4L1FA 4ZXVA 2PG0A 3BNGA 3BNFA 4KCFA 4X28A 2E80A 3D1IA 2DVLA 4XVXA 1W07A 2R0NA 2EBAA 3OWAA 1OAHA 3D9FA 2UXWA 3MKHA 3EONA 1SIQA 1IVHA 4Q5CA 2OR0A 2J7AA 2YYLA 3HWCA 4P13A 1R2JA 4Q1OA 3GNCA 3GM6A 3OIBA 4L3XA 3D9GA 4HR3A 4KTOA 2Z1QA 4Q17A 3GQTA 5K3HA 3TTBA 2WBIA 3SWOA 2JBSA 4JEKA 4Q4UA 3F29A 3LGQA 2R0MA 1FS7A 4WJYA 4L3YA 1T9GA 3OWMA 1EGCA 2C12A 3PFDA 4L3ZA 3NF4A 3BNHA 3TORA 4O5MA 2RF7A 1FS9A 1UDYA 1SIRA 2OT4A 4DOYA 4G5EA 2CX9A 2VR0A 3MXLA 2IX6A 3AFEA 3FCJA 3SF6A 1RX0A 2VIGA
chains in the Genus database with same CATH superfamily

4RM7A 3SCEA 3R7KA 1GKXA 3C46A 2ZKJA 2E81A 2EC5A 2A1TA 1RP3A 2R02A 2C0UA 2CJ6A 3SXQA 4QICA 5GJVE 1Y8NA 5BRMA 5M4KA 3P4TA 1X91A 2CJ4A 3D9DA 4IV6A 1JQIA 2JBTA 4X28C 5K3JA 4Q0TA 1EGEA 3EOMA 3TZ5A 2ZAFA 3FO3A 3MDEA 2FP2A 4FF3A 4L38A 4FF2A 3VADA 2YYIA 1R3BA 2LFWA 3D9EA 3S7WA 4H85A 1PK0A 1XG2B 4V26A 1GKZA 4OO2A 4IRNA 1FS8A 2BU8A 2BU5A 1Y0VA 2YYKA 4MPNA 2REHA 2F6LA 2RDZA 4MP7A 2FONA 1SK6A 2CJ5A 4J1VA 1S26A 2OEXA 1RJ1A 2Q8FA 5M4MA 1WS9A 5K3IA 5J6AA 2D29A 3Q0AA 3II9A 2YYMA 3MPJA 2YYGA 4N5FA 2DDHA 3M9VA 3AFFA 4AKIA 2ZO5A 2CJ8A 4Q5BA 4V25A 4AKGA 4FF1A 3B96A 3L1TA 1RJ4A 3UU9A 3UBRA 4NXLA 1GU6A 2IX5A 1XFWA 3KMLA 4F0XA 3BNJA 2EBFX 2PO4A 4W9UA 1XFXA 1IS2A 2XS1A 4HKSA 2RFQA 3RKHA 4U83A 2YYJA 3X29A 3X0YA 1EGDA 4MPEA 2JBRA 4JIOA 1UKWA 4JIZA 2VF1A 3X0XA 5K3GA 3LG1A 1BUCA 3MMOA 4ZYJA 4M9AA 2JIFA 3MPIA 1QDBA 3D6BA 1U8VA 2BTZA 3CRLA 4DZYA 3MDDA 4L1FA 4ZXVA 5M4PA 3VKHA 2PG0A 1X90A 2CJ7A 2AZEA 1K93A 4KCFA 4X28A 2E80A 2PNRA 3BNFA 3BNGA 1SC5A 2QR4A 3D1IA 1XFYA 2DVLA 3N0RA 4KSFA 4XVXA 1K8TA 3U33A 1W07A 2HJNA 2R0NA 2EBAA 4LQSB 3OWAA 2XS8A 1OAHA 3D9FA 2OEVA 2Q8IA 2AO2A 2UXWA 3MKHA 2GBBA 2Q8HA 3Q23A 4P79A 4H7QA 3Q22A 3EONA 2ZDYA 1SIQA 1XFZA 3Q24A 5M4NA 1LVCA 1IVHA 2Q8GA 3C2PA 4Q5CA 4E02A 3D2RA 5BRKA 2OR0A 3DJLA 4AI6A 2J7AA 2YYLA 3HWCA 1XFUA 4P13A 2ZDXA 4KS9A 1R2JA 4G97A 4Q1OA 5EZ3A 5B5WA 3GNCA 3GM6A 3OIBA 4L3XA 1JM6A 3D9GA 2R03A 4HR3A 4KTOA 2Z1QA 4Q17A 3GQTA 5K3HA 4H81A 3TTBA 2BU7A 2WBIA 3SWOA 2JBSA 4JEKA 2E0AA 4Q4UA 2BU6A 3F29A 3LGQA 1X8ZA 4MP2A 3TZ0A 5J71A 1Y8PA 2XQRB 1K90A 1Y8OA 2R0MA 1FS7A 2EBHX 4WJYA 4L3YA 1T9GA 3OWMA 1EGCA 2C12A 4KSAA 1PI1A 3PFDA 2BU2A 2R05A 3C3LA 3CE2A 3NF4A 3BNHA 4L3ZA 4O5MA 2RF7A 4FZ4A 3TORA 3TZ4A 1FS9A 2FP1A 4HKRA 4AKHA 4LQQB 1UDYA 1SIRA 5GJWE 2OT4A 4DOYA 3CRKA 4G5EA 1XFVA 4E00A 2CX9A 2VR0A 3MXLA 2IX6A 3AFEA 2YGWA 4E01A 2OJQA 5B5VA 5B6BA 3FCJA 3TZ2A 3VKGA 3SF6A 1RX0A 1GJVA 4FF4A 4MPCA 2VIGA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4RM7 A;  3SCE A;  3R7K A;  2E81 A;  2A1T A;  2C0U A;  3SXQ A;  3P4T A;  3D9D A;  4IV6 A;  1JQI A;  2JBT A;  4X28 C;  5K3J A;  4Q0T A;  1EGE A;  3EOM A;  2ZAF A;  3FO3 A;  3MDE A;  4L38 A;  2YYI A;  3D9E A;  3S7W A;  4OO2 A;  4IRN A;  1FS8 A;  2YYK A;  2REH A;  2RDZ A;  2FON A;  1WS9 A;  5K3I A;  2D29 A;  3II9 A;  2YYM A;  3MPJ A;  2YYG A;  4N5F A;  2DDH A;  3M9V A;  3AFF A;  2ZO5 A;  4Q5B A;  3B96 A;  3L1T A;  3UU9 A;  3UBR A;  4NXL A;  1GU6 A;  2IX5 A;  3BNJ A;  4W9U A;  1IS2 A;  2RFQ A;  3RKH A;  4U83 A;  2YYJ A;  3X0Y A;  1EGD A;  2JBR A;  1UKW A;  3X0X A;  5K3G A;  3LG1 A;  1BUC A;  3MMO A;  4ZYJ A;  4M9A A;  2JIF A;  3MPI A;  1QDB A;  3D6B A;  1U8V A;  3MDD A;  4L1F A;  4ZXV A;  2PG0 A;  3BNG A;  3BNF A;  4KCF A;  4X28 A;  2E80 A;  3D1I A;  2DVL A;  4XVX A;  1W07 A;  2R0N A;  2EBA A;  3OWA A;  1OAH A;  3D9F A;  2UXW A;  3MKH A;  3EON A;  1SIQ A;  1IVH A;  4Q5C A;  2OR0 A;  2J7A A;  2YYL A;  3HWC A;  4P13 A;  1R2J A;  4Q1O A;  3GNC A;  3GM6 A;  3OIB A;  4L3X A;  3D9G A;  4HR3 A;  4KTO A;  2Z1Q A;  4Q17 A;  3GQT A;  5K3H A;  3TTB A;  2WBI A;  3SWO A;  2JBS A;  4JEK A;  4Q4U A;  3F29 A;  3LGQ A;  2R0M A;  1FS7 A;  4WJY A;  4L3Y A;  1T9G A;  3OWM A;  1EGC A;  2C12 A;  3PFD A;  4L3Z A;  3NF4 A;  3BNH A;  3TOR A;  4O5M A;  2RF7 A;  1FS9 A;  1UDY A;  1SIR A;  2OT4 A;  4DOY A;  4G5E A;  2CX9 A;  2VR0 A;  3MXL A;  2IX6 A;  3AFE A;  3FCJ A;  3SF6 A;  1RX0 A;  2VIG A; 
#chains in the Genus database with same CATH topology
 4RM7 A;  3SCE A;  3R7K A;  1GKX A;  3C46 A;  2ZKJ A;  2E81 A;  2EC5 A;  2A1T A;  1RP3 A;  2R02 A;  2C0U A;  2CJ6 A;  3SXQ A;  4QIC A;  5GJV E;  1Y8N A;  5BRM A;  5M4K A;  3P4T A;  1X91 A;  2CJ4 A;  3D9D A;  4IV6 A;  1JQI A;  2JBT A;  4X28 C;  5K3J A;  4Q0T A;  1EGE A;  3EOM A;  3TZ5 A;  2ZAF A;  3FO3 A;  3MDE A;  2FP2 A;  4FF3 A;  4L38 A;  4FF2 A;  3VAD A;  2YYI A;  1R3B A;  2LFW A;  3D9E A;  3S7W A;  4H85 A;  1PK0 A;  1XG2 B;  4V26 A;  1GKZ A;  4OO2 A;  4IRN A;  1FS8 A;  2BU8 A;  2BU5 A;  1Y0V A;  2YYK A;  4MPN A;  2REH A;  2F6L A;  2RDZ A;  4MP7 A;  2FON A;  1SK6 A;  2CJ5 A;  4J1V A;  1S26 A;  2OEX A;  1RJ1 A;  2Q8F A;  5M4M A;  1WS9 A;  5K3I A;  5J6A A;  2D29 A;  3Q0A A;  3II9 A;  2YYM A;  3MPJ A;  2YYG A;  4N5F A;  2DDH A;  3M9V A;  3AFF A;  4AKI A;  2ZO5 A;  2CJ8 A;  4Q5B A;  4V25 A;  4AKG A;  4FF1 A;  3B96 A;  3L1T A;  1RJ4 A;  3UU9 A;  3UBR A;  4NXL A;  1GU6 A;  2IX5 A;  1XFW A;  3KML A;  4F0X A;  3BNJ A;  2EBF X;  2PO4 A;  4W9U A;  1XFX A;  1IS2 A;  2XS1 A;  4HKS A;  2RFQ A;  3RKH A;  4U83 A;  2YYJ A;  3X29 A;  3X0Y A;  1EGD A;  4MPE A;  2JBR A;  4JIO A;  1UKW A;  4JIZ A;  2VF1 A;  3X0X A;  5K3G A;  3LG1 A;  1BUC A;  3MMO A;  4ZYJ A;  4M9A A;  2JIF A;  3MPI A;  1QDB A;  3D6B A;  1U8V A;  2BTZ A;  3CRL A;  4DZY A;  3MDD A;  4L1F A;  4ZXV A;  5M4P A;  3VKH A;  2PG0 A;  1X90 A;  2CJ7 A;  2AZE A;  1K93 A;  4KCF A;  4X28 A;  2E80 A;  2PNR A;  3BNF A;  3BNG A;  1SC5 A;  2QR4 A;  3D1I A;  1XFY A;  2DVL A;  3N0R A;  4KSF A;  4XVX A;  1K8T A;  3U33 A;  1W07 A;  2HJN A;  2R0N A;  2EBA A;  4LQS B;  3OWA A;  2XS8 A;  1OAH A;  3D9F A;  2OEV A;  2Q8I A;  2AO2 A;  2UXW A;  3MKH A;  2GBB A;  2Q8H A;  3Q23 A;  4P79 A;  4H7Q A;  3Q22 A;  3EON A;  2ZDY A;  1SIQ A;  1XFZ A;  3Q24 A;  5M4N A;  1LVC A;  1IVH A;  2Q8G A;  3C2P A;  4Q5C A;  4E02 A;  3D2R A;  5BRK A;  2OR0 A;  3DJL A;  4AI6 A;  2J7A A;  2YYL A;  3HWC A;  1XFU A;  4P13 A;  2ZDX A;  4KS9 A;  1R2J A;  4G97 A;  4Q1O A;  5EZ3 A;  5B5W A;  3GNC A;  3GM6 A;  3OIB A;  4L3X A;  1JM6 A;  3D9G A;  2R03 A;  4HR3 A;  4KTO A;  2Z1Q A;  4Q17 A;  3GQT A;  5K3H A;  4H81 A;  3TTB A;  2BU7 A;  2WBI A;  3SWO A;  2JBS A;  4JEK A;  2E0A A;  4Q4U A;  2BU6 A;  3F29 A;  3LGQ A;  1X8Z A;  4MP2 A;  3TZ0 A;  5J71 A;  1Y8P A;  2XQR B;  1K90 A;  1Y8O A;  2R0M A;  1FS7 A;  2EBH X;  4WJY A;  4L3Y A;  1T9G A;  3OWM A;  1EGC A;  2C12 A;  4KSA A;  1PI1 A;  3PFD A;  2BU2 A;  2R05 A;  3C3L A;  3CE2 A;  3NF4 A;  3BNH A;  4L3Z A;  4O5M A;  2RF7 A;  4FZ4 A;  3TOR A;  3TZ4 A;  1FS9 A;  2FP1 A;  4HKR A;  4AKH A;  4LQQ B;  1UDY A;  1SIR A;  5GJW E;  2OT4 A;  4DOY A;  3CRK A;  4G5E A;  1XFV A;  4E00 A;  2CX9 A;  2VR0 A;  3MXL A;  2IX6 A;  3AFE A;  2YGW A;  4E01 A;  2OJQ A;  5B5V A;  5B6B A;  3FCJ A;  3TZ2 A;  3VKG A;  3SF6 A;  1RX0 A;  1GJV A;  4FF4 A;  4MPC A;  2VIG A; 
#chains in the Genus database with same CATH homology
 4RM7 A;  3SCE A;  3R7K A;  2E81 A;  2A1T A;  2C0U A;  3SXQ A;  3P4T A;  3D9D A;  4IV6 A;  1JQI A;  2JBT A;  4X28 C;  5K3J A;  4Q0T A;  1EGE A;  3EOM A;  2ZAF A;  3FO3 A;  3MDE A;  4L38 A;  2YYI A;  3D9E A;  3S7W A;  4OO2 A;  4IRN A;  1FS8 A;  2YYK A;  2REH A;  2RDZ A;  2FON A;  1WS9 A;  5K3I A;  2D29 A;  3II9 A;  2YYM A;  3MPJ A;  2YYG A;  4N5F A;  2DDH A;  3M9V A;  3AFF A;  2ZO5 A;  4Q5B A;  3B96 A;  3L1T A;  3UU9 A;  3UBR A;  4NXL A;  1GU6 A;  2IX5 A;  3BNJ A;  4W9U A;  1IS2 A;  2RFQ A;  3RKH A;  4U83 A;  2YYJ A;  3X0Y A;  1EGD A;  2JBR A;  1UKW A;  3X0X A;  5K3G A;  3LG1 A;  1BUC A;  3MMO A;  4ZYJ A;  4M9A A;  2JIF A;  3MPI A;  1QDB A;  3D6B A;  1U8V A;  3MDD A;  4L1F A;  4ZXV A;  2PG0 A;  3BNG A;  3BNF A;  4KCF A;  4X28 A;  2E80 A;  3D1I A;  2DVL A;  4XVX A;  1W07 A;  2R0N A;  2EBA A;  3OWA A;  1OAH A;  3D9F A;  2UXW A;  3MKH A;  3EON A;  1SIQ A;  1IVH A;  4Q5C A;  2OR0 A;  2J7A A;  2YYL A;  3HWC A;  4P13 A;  1R2J A;  4Q1O A;  3GNC A;  3GM6 A;  3OIB A;  4L3X A;  3D9G A;  4HR3 A;  4KTO A;  2Z1Q A;  4Q17 A;  3GQT A;  5K3H A;  3TTB A;  2WBI A;  3SWO A;  2JBS A;  4JEK A;  4Q4U A;  3F29 A;  3LGQ A;  2R0M A;  1FS7 A;  4WJY A;  4L3Y A;  1T9G A;  3OWM A;  1EGC A;  2C12 A;  3PFD A;  4L3Z A;  3NF4 A;  3BNH A;  3TOR A;  4O5M A;  2RF7 A;  1FS9 A;  1UDY A;  1SIR A;  2OT4 A;  4DOY A;  4G5E A;  2CX9 A;  2VR0 A;  3MXL A;  2IX6 A;  3AFE A;  3FCJ A;  3SF6 A;  1RX0 A;  2VIG A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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2UXWA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations