3P4T | Genus

Total Genus 152

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	152
sequence length	381
structure length	381
Chain Sequence	SIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLLGAGFPEDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMIASGDQRLIDTYVRPTLRGEKIGALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYITSGVRADYVVTAARTGGPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSENTGFAQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGMARRIDVARVYTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTSLAAKTLGFQS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 381 atoms

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381 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxidoreductase
source organism	Mycobacterium smegmatis
publication title	Increasing the structural coverage of tuberculosis drug targets. pubmed doi rcsb
molecule keywords	Putative acyl-CoA dehydrogenase
total genus	152
structure length	381
sequence length	381
chains with identical sequence	B
ec nomenclature	ec 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase.
pdb deposition date	2010-10-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00441	Acyl-CoA_dh_1	Acyl-CoA dehydrogenase, C-terminal domain
A	PF02770	Acyl-CoA_dh_M	Acyl-CoA dehydrogenase, middle domain
A	PF02771	Acyl-CoA_dh_N	Acyl-CoA dehydrogenase, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A; domain 1	Acyl-CoA dehydrogenase/oxidase, N-terminal domain	3p4tA01
1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A, domain 3	3p4tA03
2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A; domain 2	Butyryl-CoA Dehydrogenase, subunit A, domain 2	3p4tA02

2CX9A 3UU9A 4L3XA 2ZAFA 3PFDA 3MDDA 2PG0A 5K3JA 2RF7A 2Z1QA 4XVXA 2VIGA 3R7KA 2YYIA 1BUCA 3NF4A 4Q0TA 3X0YA 3LGQA 3P4TA 1U8VA 3D9FA 4IRNA 4X28A 2OT4A 2R0MA 3MMOA 2REHA 4P13A 3OWMA 3BNHA 2JIFA 4IV6A 3BNJA 1EGDA 4OO2A 1QDBA 2UXWA 4RM7A 3OWAA 3B96A 5K3IA 3SWOA 3L1TA 3D9EA 4ZYJA 4L3YA 4ZXVA 1W07A 3FO3A 3BNFA 3OIBA 4Q17A 5K3GA 4NXLA 4JEKA 3GQTA 3EONA 2YYKA 4KTOA 2YYLA 5K3HA 3TORA 3II9A 1GU6A 4Q5BA 3MDEA 4Q1OA 4DOYA 3EOMA 2EBAA 3D6BA 4L3ZA 2ZO5A 2JBSA 3MPJA 3D9GA 1IVHA 3M9VA 1R2JA 4HR3A 1OAHA 4O5MA 2WBIA 4U83A 2IX5A 1IS2A 3SF6A 4M9AA 3FCJA 3MXLA 3SCEA 1EGEA 3BNGA 2D29A 1FS8A 2RDZA 2IX6A 2C0UA 2VR0A 4Q4UA 3D9DA 2YYJA 1UKWA 1UDYA 4W9UA 1WS9A 2RFQA 1SIRA 1RX0A 2J7AA 3MPIA 2DVLA 4WJYA 2DDHA 4Q5CA 2C12A 4L38A 3D1IA 3LG1A 3GNCA 1JQIA 1FS7A 3X0XA 2YYMA 4L1FA 2OR0A 3HWCA 1FS9A 4X28C 4N5FA 1SIQA 4G5EA 3TTBA 2FONA 3UBRA 2E81A 4KCFA 2JBRA 2E80A 1EGCA 2YYGA 3AFFA 3SXQA 2A1TA 3AFEA 3S7WA 3GM6A 2JBTA 3RKHA 2R0NA 3F29A 1T9GA 3MKHA
chains in the Genus database with same CATH superfamily

1Y8OA 1X91A 2CX9A 4QICA 3UU9A 4L3XA 2OJQA 3U33A 2ZAFA 3PFDA 4J1VA 3MDDA 4MP2A 2PG0A 5K3JA 1XFXA 4LQSB 2RF7A 2Z1QA 5M4MA 4XVXA 2VIGA 3R7KA 1XG2B 1LVCA 2FP2A 1BUCA 2XS8A 2YYIA 4FF1A 1Y0VA 3NF4A 4Q0TA 4JIOA 3X0YA 3CRLA 3KMLA 3LGQA 5B6BA 3C46A 2LFWA 3P4TA 1U8VA 2EC5A 2CJ6A 2R05A 4HKRA 5B5VA 5B5WA 5M4PA 2BU5A 3D9FA 4IRNA 3TZ2A 4X28A 2OT4A 2R0MA 3VKGA 3MMOA 5M4NA 4KS9A 2REHA 5BRKA 4P13A 1R3BA 1XFWA 3OWMA 3BNHA 1GJVA 1K93A 2JIFA 4MPNA 4IV6A 3Q22A 3BNJA 4DZYA 1EGDA 4OO2A 1XFZA 4KSFA 1QDBA 2Q8HA 2UXWA 2ZDYA 1RJ1A 4RM7A 1RP3A 3OWAA 4V25A 4AKIA 3B96A 5K3IA 3SWOA 3L1TA 3D9EA 1PK0A 4ZYJA 2CJ5A 1X90A 4H7QA 4HKSA 4L3YA 4H85A 3Q23A 1XFVA 4E00A 4ZXVA 1W07A 2ZDXA 3FO3A 3Q0AA 3BNFA 2CJ7A 2FP1A 1GKXA 3OIBA 2PNRA 4Q17A 3X29A 2XQRB 5K3GA 4G97A 3C3LA 4FF2A 1PI1A 2CJ8A 4NXLA 4JEKA 2AZEA 3Q24A 3GQTA 2ZKJA 3EONA 2GBBA 5M4KA 4F0XA 2YYKA 2CJ4A 4KTOA 2YYLA 4P79A 5K3HA 3TORA 3II9A 1GU6A 2E0AA 5BRMA 4Q5BA 3MDEA 4MPEA 4Q1OA 4DOYA 3EOMA 3SCEA 2EBAA 3D6BA 4L3ZA 2ZO5A 2JBSA 4JIZA 1RJ4A 3MPJA 5J71A 3D9GA 1IVHA 3CRKA 3M9VA 5GJVE 4MPCA 1R2JA 4HR3A 1X8ZA 2EBHX 2QR4A 1OAHA 1Y8NA 2Q8FA 4O5MA 2WBIA 4U83A 4V26A 2F6LA 2HJNA 2IX5A 1IS2A 3SF6A 2BTZA 4M9AA 3TZ4A 3FCJA 3MXLA 4KSAA 1EGEA 1K90A 2D29A 1FS8A 2RDZA 3BNGA 4H81A 4FZ4A 4AKGA 2IX6A 2C0UA 3DJLA 1GKZA 3D2RA 4FF3A 2VR0A 1K8TA 3TZ5A 2OEVA 4Q4UA 3D9DA 2EBFX 2YYJA 1UKWA 2BU7A 2PO4A 2Q8GA 1UDYA 4W9UA 1WS9A 1SK6A 3VKHA 2BU6A 2RFQA 1S26A 3CE2A 1SIRA 1RX0A 3TZ0A 2J7AA 3MPIA 2DVLA 4WJYA 4E02A 2AO2A 2DDHA 2R03A 4Q5CA 4AI6A 2C12A 1SC5A 2XS1A 4L38A 5EZ3A 3D1IA 3LG1A 3GNCA 1JQIA 1FS7A 4LQQB 4E01A 1XFUA 5GJWE 4MP7A 3X0XA 2YYMA 4L1FA 3C2PA 4AKHA 2OR0A 2Q8IA 3HWCA 1FS9A 1XFYA 4X28C 4N5FA 1SIQA 4G5EA 3TTBA 2FONA 3UBRA 2E81A 4KCFA 2VF1A 1JM6A 1Y8PA 2JBRA 4FF4A 2BU2A 5J6AA 2E80A 1EGCA 2YYGA 3AFFA 3VADA 2R02A 3SXQA 2A1TA 3AFEA 3N0RA 3S7WA 3GM6A 2YGWA 2OEXA 2JBTA 3RKHA 2R0NA 3F29A 1T9GA 3MKHA 2BU8A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2CX9 A;  3UU9 A;  4L3X A;  2ZAF A;  3PFD A;  3MDD A;  2PG0 A;  5K3J A;  2RF7 A;  2Z1Q A;  4XVX A;  2VIG A;  3R7K A;  2YYI A;  1BUC A;  3NF4 A;  4Q0T A;  3X0Y A;  3LGQ A;  3P4T A;  1U8V A;  3D9F A;  4IRN A;  4X28 A;  2OT4 A;  2R0M A;  3MMO A;  2REH A;  4P13 A;  3OWM A;  3BNH A;  2JIF A;  4IV6 A;  3BNJ A;  1EGD A;  4OO2 A;  1QDB A;  2UXW A;  4RM7 A;  3OWA A;  3B96 A;  5K3I A;  3SWO A;  3L1T A;  3D9E A;  4ZYJ A;  4L3Y A;  4ZXV A;  1W07 A;  3FO3 A;  3BNF A;  3OIB A;  4Q17 A;  5K3G A;  4NXL A;  4JEK A;  3GQT A;  3EON A;  2YYK A;  4KTO A;  2YYL A;  5K3H A;  3TOR A;  3II9 A;  1GU6 A;  4Q5B A;  3MDE A;  4Q1O A;  4DOY A;  3EOM A;  2EBA A;  3D6B A;  4L3Z A;  2ZO5 A;  2JBS A;  3MPJ A;  3D9G A;  1IVH A;  3M9V A;  1R2J A;  4HR3 A;  1OAH A;  4O5M A;  2WBI A;  4U83 A;  2IX5 A;  1IS2 A;  3SF6 A;  4M9A A;  3FCJ A;  3MXL A;  3SCE A;  1EGE A;  3BNG A;  2D29 A;  1FS8 A;  2RDZ A;  2IX6 A;  2C0U A;  2VR0 A;  4Q4U A;  3D9D A;  2YYJ A;  1UKW A;  1UDY A;  4W9U A;  1WS9 A;  2RFQ A;  1SIR A;  1RX0 A;  2J7A A;  3MPI A;  2DVL A;  4WJY A;  2DDH A;  4Q5C A;  2C12 A;  4L38 A;  3D1I A;  3LG1 A;  3GNC A;  1JQI A;  1FS7 A;  3X0X A;  2YYM A;  4L1F A;  2OR0 A;  3HWC A;  1FS9 A;  4X28 C;  4N5F A;  1SIQ A;  4G5E A;  3TTB A;  2FON A;  3UBR A;  2E81 A;  4KCF A;  2JBR A;  2E80 A;  1EGC A;  2YYG A;  3AFF A;  3SXQ A;  2A1T A;  3AFE A;  3S7W A;  3GM6 A;  2JBT A;  3RKH A;  2R0N A;  3F29 A;  1T9G A;  3MKH A; 
#chains in the Genus database with same CATH topology
 1Y8O A;  1X91 A;  2CX9 A;  4QIC A;  3UU9 A;  4L3X A;  2OJQ A;  3U33 A;  2ZAF A;  3PFD A;  4J1V A;  3MDD A;  4MP2 A;  2PG0 A;  5K3J A;  1XFX A;  4LQS B;  2RF7 A;  2Z1Q A;  5M4M A;  4XVX A;  2VIG A;  3R7K A;  1XG2 B;  1LVC A;  2FP2 A;  1BUC A;  2XS8 A;  2YYI A;  4FF1 A;  1Y0V A;  3NF4 A;  4Q0T A;  4JIO A;  3X0Y A;  3CRL A;  3KML A;  3LGQ A;  5B6B A;  3C46 A;  2LFW A;  3P4T A;  1U8V A;  2EC5 A;  2CJ6 A;  2R05 A;  4HKR A;  5B5V A;  5B5W A;  5M4P A;  2BU5 A;  3D9F A;  4IRN A;  3TZ2 A;  4X28 A;  2OT4 A;  2R0M A;  3VKG A;  3MMO A;  5M4N A;  4KS9 A;  2REH A;  5BRK A;  4P13 A;  1R3B A;  1XFW A;  3OWM A;  3BNH A;  1GJV A;  1K93 A;  2JIF A;  4MPN A;  4IV6 A;  3Q22 A;  3BNJ A;  4DZY A;  1EGD A;  4OO2 A;  1XFZ A;  4KSF A;  1QDB A;  2Q8H A;  2UXW A;  2ZDY A;  1RJ1 A;  4RM7 A;  1RP3 A;  3OWA A;  4V25 A;  4AKI A;  3B96 A;  5K3I A;  3SWO A;  3L1T A;  3D9E A;  1PK0 A;  4ZYJ A;  2CJ5 A;  1X90 A;  4H7Q A;  4HKS A;  4L3Y A;  4H85 A;  3Q23 A;  1XFV A;  4E00 A;  4ZXV A;  1W07 A;  2ZDX A;  3FO3 A;  3Q0A A;  3BNF A;  2CJ7 A;  2FP1 A;  1GKX A;  3OIB A;  2PNR A;  4Q17 A;  3X29 A;  2XQR B;  5K3G A;  4G97 A;  3C3L A;  4FF2 A;  1PI1 A;  2CJ8 A;  4NXL A;  4JEK A;  2AZE A;  3Q24 A;  3GQT A;  2ZKJ A;  3EON A;  2GBB A;  5M4K A;  4F0X A;  2YYK A;  2CJ4 A;  4KTO A;  2YYL A;  4P79 A;  5K3H A;  3TOR A;  3II9 A;  1GU6 A;  2E0A A;  5BRM A;  4Q5B A;  3MDE A;  4MPE A;  4Q1O A;  4DOY A;  3EOM A;  3SCE A;  2EBA A;  3D6B A;  4L3Z A;  2ZO5 A;  2JBS A;  4JIZ A;  1RJ4 A;  3MPJ A;  5J71 A;  3D9G A;  1IVH A;  3CRK A;  3M9V A;  5GJV E;  4MPC A;  1R2J A;  4HR3 A;  1X8Z A;  2EBH X;  2QR4 A;  1OAH A;  1Y8N A;  2Q8F A;  4O5M A;  2WBI A;  4U83 A;  4V26 A;  2F6L A;  2HJN A;  2IX5 A;  1IS2 A;  3SF6 A;  2BTZ A;  4M9A A;  3TZ4 A;  3FCJ A;  3MXL A;  4KSA A;  1EGE A;  1K90 A;  2D29 A;  1FS8 A;  2RDZ A;  3BNG A;  4H81 A;  4FZ4 A;  4AKG A;  2IX6 A;  2C0U A;  3DJL A;  1GKZ A;  3D2R A;  4FF3 A;  2VR0 A;  1K8T A;  3TZ5 A;  2OEV A;  4Q4U A;  3D9D A;  2EBF X;  2YYJ A;  1UKW A;  2BU7 A;  2PO4 A;  2Q8G A;  1UDY A;  4W9U A;  1WS9 A;  1SK6 A;  3VKH A;  2BU6 A;  2RFQ A;  1S26 A;  3CE2 A;  1SIR A;  1RX0 A;  3TZ0 A;  2J7A A;  3MPI A;  2DVL A;  4WJY A;  4E02 A;  2AO2 A;  2DDH A;  2R03 A;  4Q5C A;  4AI6 A;  2C12 A;  1SC5 A;  2XS1 A;  4L38 A;  5EZ3 A;  3D1I A;  3LG1 A;  3GNC A;  1JQI A;  1FS7 A;  4LQQ B;  4E01 A;  1XFU A;  5GJW E;  4MP7 A;  3X0X A;  2YYM A;  4L1F A;  3C2P A;  4AKH A;  2OR0 A;  2Q8I A;  3HWC A;  1FS9 A;  1XFY A;  4X28 C;  4N5F A;  1SIQ A;  4G5E A;  3TTB A;  2FON A;  3UBR A;  2E81 A;  4KCF A;  2VF1 A;  1JM6 A;  1Y8P A;  2JBR A;  4FF4 A;  2BU2 A;  5J6A A;  2E80 A;  1EGC A;  2YYG A;  3AFF A;  3VAD A;  2R02 A;  3SXQ A;  2A1T A;  3AFE A;  3N0R A;  3S7W A;  3GM6 A;  2YGW A;  2OEX A;  2JBT A;  3RKH A;  2R0N A;  3F29 A;  1T9G A;  3MKH A;  2BU8 A; 
#chains in the Genus database with same CATH homology
 2CX9 A;  3UU9 A;  4L3X A;  2ZAF A;  3PFD A;  3MDD A;  2PG0 A;  5K3J A;  2RF7 A;  2Z1Q A;  4XVX A;  2VIG A;  3R7K A;  2YYI A;  1BUC A;  3NF4 A;  4Q0T A;  3X0Y A;  3LGQ A;  3P4T A;  1U8V A;  3D9F A;  4IRN A;  4X28 A;  2OT4 A;  2R0M A;  3MMO A;  2REH A;  4P13 A;  3OWM A;  3BNH A;  2JIF A;  4IV6 A;  3BNJ A;  1EGD A;  4OO2 A;  1QDB A;  2UXW A;  4RM7 A;  3OWA A;  3B96 A;  5K3I A;  3SWO A;  3L1T A;  3D9E A;  4ZYJ A;  4L3Y A;  4ZXV A;  1W07 A;  3FO3 A;  3BNF A;  3OIB A;  4Q17 A;  5K3G A;  4NXL A;  4JEK A;  3GQT A;  3EON A;  2YYK A;  4KTO A;  2YYL A;  5K3H A;  3TOR A;  3II9 A;  1GU6 A;  4Q5B A;  3MDE A;  4Q1O A;  4DOY A;  3EOM A;  2EBA A;  3D6B A;  4L3Z A;  2ZO5 A;  2JBS A;  3MPJ A;  3D9G A;  1IVH A;  3M9V A;  1R2J A;  4HR3 A;  1OAH A;  4O5M A;  2WBI A;  4U83 A;  2IX5 A;  1IS2 A;  3SF6 A;  4M9A A;  3FCJ A;  3MXL A;  3SCE A;  1EGE A;  3BNG A;  2D29 A;  1FS8 A;  2RDZ A;  2IX6 A;  2C0U A;  2VR0 A;  4Q4U A;  3D9D A;  2YYJ A;  1UKW A;  1UDY A;  4W9U A;  1WS9 A;  2RFQ A;  1SIR A;  1RX0 A;  2J7A A;  3MPI A;  2DVL A;  4WJY A;  2DDH A;  4Q5C A;  2C12 A;  4L38 A;  3D1I A;  3LG1 A;  3GNC A;  1JQI A;  1FS7 A;  3X0X A;  2YYM A;  4L1F A;  2OR0 A;  3HWC A;  1FS9 A;  4X28 C;  4N5F A;  1SIQ A;  4G5E A;  3TTB A;  2FON A;  3UBR A;  2E81 A;  4KCF A;  2JBR A;  2E80 A;  1EGC A;  2YYG A;  3AFF A;  3SXQ A;  2A1T A;  3AFE A;  3S7W A;  3GM6 A;  2JBT A;  3RKH A;  2R0N A;  3F29 A;  1T9G A;  3MKH A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3P4TA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations