3AFFA

Crystal structure of the hsaa monooxygenase from m. tuberculosis
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
388
structure length
366
Chain Sequence
RDAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPGDTMV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Hydroxylase, putative
total genus 144
structure length 366
sequence length 388
chains with identical sequence B
ec nomenclature ec 1.14.14.12: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase.
pdb deposition date 2010-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08028 Acyl-CoA_dh_2 Acyl-CoA dehydrogenase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3affA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3affA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3affA02
4ZXVA 4L3XA 3SXQA 1FS7A 4Q4UA 1FS9A 2ZO5A 3UU9A 3F29A 5K3IA 4Q5BA 3R7KA 3EOMA 3SF6A 2YYKA 3GQTA 3D6BA 3B96A 2YYGA 3X0XA 2C0UA 3MKHA 1R2JA 3SCEA 3OWMA 4X28A 2WBIA 1T9GA 3MPJA 4M9AA 2CX9A 4Q17A 4NXLA 4IRNA 5K3HA 2FONA 2A1TA 4RM7A 1FS8A 2YYIA 4L1FA 4W9UA 2VIGA 4ZYJA 1W07A 3D9FA 2VR0A 2J7AA 2UXWA 2YYMA 4X28C 4Q5CA 3OIBA 3MPIA 2OR0A 4KCFA 3AFEA 3TTBA 3OWAA 3X0YA 3M9VA 4G5EA 4L38A 2E81A 1IVHA 4DOYA 4HR3A 4P13A 4U83A 2JBTA 4L3YA 4O5MA 2Z1QA 2RFQA 4OO2A 3D9GA 3FO3A 1IS2A 2ZAFA 1RX0A 2JBSA 1EGCA 1EGEA 2YYLA 3AFFA 3BNFA 2JIFA 2OT4A 2C12A 3GM6A 2IX6A 5K3JA 1WS9A 4Q1OA 2D29A 2RF7A 3HWCA 3II9A 3FCJA 1OAHA 3NF4A 3D9EA 3P4TA 3MXLA 3MMOA 1QDBA 3LG1A 3MDDA 1SIRA 1UKWA 2REHA 3BNJA 1U8VA 1EGDA 2R0MA 2JBRA 1BUCA 5K3GA 3EONA 2R0NA 3GNCA 3BNGA 4WJYA 1GU6A 4XVXA 2EBAA 3MDEA 3TORA 3S7WA 3BNHA 3L1TA 4L3ZA 3UBRA 2PG0A 3D9DA 3LGQA 2RDZA 1SIQA 4JEKA 1JQIA 4KTOA 2IX5A 2DVLA 2YYJA 4IV6A 4Q0TA 2DDHA 2E80A 3RKHA 3D1IA 3PFDA 4N5FA 3SWOA 1UDYA
chains in the Genus database with same CATH superfamily
4ZXVA 1JM6A 1XFUA 4L3XA 3SXQA 2E0AA 1FS7A 3CRKA 4Q4UA 1FS9A 2ZO5A 3UU9A 2CJ5A 1GJVA 2ZKJA 3F29A 5K3IA 4Q5BA 4LQQB 4G97A 3R7KA 3U33A 4V25A 3TZ4A 3EOMA 2BU2A 3SF6A 2YYKA 3GQTA 3D6BA 5J6AA 3B96A 1K90A 1RP3A 2YYGA 2CJ6A 3X0XA 2OEXA 4KSFA 2C0UA 3MKHA 2LFWA 1R2JA 3SCEA 4E02A 3OWMA 3TZ5A 2PNRA 2EBFX 4X28A 2Q8GA 2WBIA 4F0XA 1T9GA 2ZDXA 3MPJA 5BRMA 4M9AA 2CX9A 4HKRA 4Q17A 4NXLA 2BU6A 2F6LA 4IRNA 5K3HA 2FONA 1XFZA 1GKZA 2OJQA 2A1TA 2QR4A 2AO2A 4RM7A 1FS8A 2YYIA 4L1FA 4W9UA 4J1VA 5B6BA 3TZ2A 2VIGA 4AKGA 3N0RA 4ZYJA 1W07A 4FF2A 3D9FA 2VR0A 2J7AA 2UXWA 2YYMA 4X28C 3CRLA 3KMLA 5M4MA 2CJ4A 2GBBA 3OIBA 3MPIA 2CJ7A 4Q5CA 4E01A 2OR0A 1PI1A 4KCFA 3AFEA 3TTBA 3OWAA 3X0YA 3Q23A 3M9VA 1K8TA 2OEVA 4G5EA 4H81A 2BTZA 4L38A 5GJWE 4MPCA 3C2PA 2E81A 2PO4A 1IVHA 4DOYA 4HR3A 4P13A 5B5WA 4HKSA 1LVCA 4U83A 2JBTA 5M4KA 4L3YA 4O5MA 4JIZA 2Z1QA 2RFQA 4OO2A 3D9GA 4FF4A 4V26A 4MP7A 3FO3A 1IS2A 2ZAFA 1RX0A 2JBSA 1EGCA 1EGEA 2YYLA 4KSAA 4AKHA 5J71A 2EC5A 3VKHA 4FF3A 3AFFA 5BRKA 2XQRB 3BNFA 4LQSB 2JIFA 2XS8A 2OT4A 5M4PA 3Q24A 2C12A 3GM6A 2IX6A 5K3JA 1XFXA 1WS9A 1Y8PA 4Q1OA 2D29A 2RF7A 3HWCA 4MP2A 2Q8HA 3II9A 3FCJA 4MPNA 5GJVE 1OAHA 1S26A 3NF4A 2XS1A 3D9EA 3P4TA 2CJ8A 3MXLA 3MMOA 4H7QA 1QDBA 3LG1A 3MDDA 2HJNA 5EZ3A 1SIRA 1UKWA 2REHA 1XG2B 2Q8FA 2FP1A 3BNJA 1U8VA 3TZ0A 3CE2A 1EGDA 2ZDYA 2R0MA 1Y0VA 4QICA 3C3LA 1XFVA 2BU5A 2JBRA 4H85A 1BUCA 5K3GA 1Y8NA 3EONA 2BU7A 3D2RA 2R0NA 1X91A 2BU8A 2YGWA 1RJ4A 2EBHX 4P79A 3GNCA 3BNGA 4WJYA 1GU6A 2Q8IA 3VADA 4XVXA 1RJ1A 2EBAA 2R02A 3MDEA 4AI6A 3TORA 3S7WA 3BNHA 3DJLA 3L1TA 2AZEA 4L3ZA 5B5VA 3UBRA 3Q22A 2FP2A 4DZYA 1XFWA 2PG0A 3D9DA 2R05A 4FF1A 3LGQA 2RDZA 1SIQA 4JEKA 4E00A 3X29A 1JQIA 1X90A 4KTOA 2IX5A 2DVLA 1K93A 2YYJA 4IV6A 1R3BA 4Q0TA 2VF1A 1SK6A 2DDHA 1GKXA 1PK0A 1SC5A 2E80A 3RKHA 3Q0AA 1Y8OA 1X8ZA 3D1IA 3PFDA 4JIOA 1XFYA 4AKIA 3VKGA 4FZ4A 4MPEA 4N5FA 4KS9A 3C46A 3SWOA 2R03A 1UDYA 5M4NA
chains in the Genus database with same CATH topology
4ZXVA 4L3XA 3SXQA 1FS7A 4Q4UA 1FS9A 2ZO5A 3UU9A 3F29A 5K3IA 4Q5BA 3R7KA 3EOMA 3SF6A 2YYKA 3GQTA 3D6BA 3B96A 2YYGA 3X0XA 2C0UA 3MKHA 1R2JA 3SCEA 3OWMA 4X28A 2WBIA 1T9GA 3MPJA 4M9AA 2CX9A 4Q17A 4NXLA 4IRNA 5K3HA 2FONA 2A1TA 4RM7A 1FS8A 2YYIA 4L1FA 4W9UA 2VIGA 4ZYJA 1W07A 3D9FA 2VR0A 2J7AA 2UXWA 2YYMA 4X28C 4Q5CA 3OIBA 3MPIA 2OR0A 4KCFA 3AFEA 3TTBA 3OWAA 3X0YA 3M9VA 4G5EA 4L38A 2E81A 1IVHA 4DOYA 4HR3A 4P13A 4U83A 2JBTA 4L3YA 4O5MA 2Z1QA 2RFQA 4OO2A 3D9GA 3FO3A 1IS2A 2ZAFA 1RX0A 2JBSA 1EGCA 1EGEA 2YYLA 3AFFA 3BNFA 2JIFA 2OT4A 2C12A 3GM6A 2IX6A 5K3JA 1WS9A 4Q1OA 2D29A 2RF7A 3HWCA 3II9A 3FCJA 1OAHA 3NF4A 3D9EA 3P4TA 3MXLA 3MMOA 1QDBA 3LG1A 3MDDA 1SIRA 1UKWA 2REHA 3BNJA 1U8VA 1EGDA 2R0MA 2JBRA 1BUCA 5K3GA 3EONA 2R0NA 3GNCA 3BNGA 4WJYA 1GU6A 4XVXA 2EBAA 3MDEA 3TORA 3S7WA 3BNHA 3L1TA 4L3ZA 3UBRA 2PG0A 3D9DA 3LGQA 2RDZA 1SIQA 4JEKA 1JQIA 4KTOA 2IX5A 2DVLA 2YYJA 4IV6A 4Q0TA 2DDHA 2E80A 3RKHA 3D1IA 3PFDA 4N5FA 3SWOA 1UDYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZXV A;  4L3X A;  3SXQ A;  1FS7 A;  4Q4U A;  1FS9 A;  2ZO5 A;  3UU9 A;  3F29 A;  5K3I A;  4Q5B A;  3R7K A;  3EOM A;  3SF6 A;  2YYK A;  3GQT A;  3D6B A;  3B96 A;  2YYG A;  3X0X A;  2C0U A;  3MKH A;  1R2J A;  3SCE A;  3OWM A;  4X28 A;  2WBI A;  1T9G A;  3MPJ A;  4M9A A;  2CX9 A;  4Q17 A;  4NXL A;  4IRN A;  5K3H A;  2FON A;  2A1T A;  4RM7 A;  1FS8 A;  2YYI A;  4L1F A;  4W9U A;  2VIG A;  4ZYJ A;  1W07 A;  3D9F A;  2VR0 A;  2J7A A;  2UXW A;  2YYM A;  4X28 C;  4Q5C A;  3OIB A;  3MPI A;  2OR0 A;  4KCF A;  3AFE A;  3TTB A;  3OWA A;  3X0Y A;  3M9V A;  4G5E A;  4L38 A;  2E81 A;  1IVH A;  4DOY A;  4HR3 A;  4P13 A;  4U83 A;  2JBT A;  4L3Y A;  4O5M A;  2Z1Q A;  2RFQ A;  4OO2 A;  3D9G A;  3FO3 A;  1IS2 A;  2ZAF A;  1RX0 A;  2JBS A;  1EGC A;  1EGE A;  2YYL A;  3AFF A;  3BNF A;  2JIF A;  2OT4 A;  2C12 A;  3GM6 A;  2IX6 A;  5K3J A;  1WS9 A;  4Q1O A;  2D29 A;  2RF7 A;  3HWC A;  3II9 A;  3FCJ A;  1OAH A;  3NF4 A;  3D9E A;  3P4T A;  3MXL A;  3MMO A;  1QDB A;  3LG1 A;  3MDD A;  1SIR A;  1UKW A;  2REH A;  3BNJ A;  1U8V A;  1EGD A;  2R0M A;  2JBR A;  1BUC A;  5K3G A;  3EON A;  2R0N A;  3GNC A;  3BNG A;  4WJY A;  1GU6 A;  4XVX A;  2EBA A;  3MDE A;  3TOR A;  3S7W A;  3BNH A;  3L1T A;  4L3Z A;  3UBR A;  2PG0 A;  3D9D A;  3LGQ A;  2RDZ A;  1SIQ A;  4JEK A;  1JQI A;  4KTO A;  2IX5 A;  2DVL A;  2YYJ A;  4IV6 A;  4Q0T A;  2DDH A;  2E80 A;  3RKH A;  3D1I A;  3PFD A;  4N5F A;  3SWO A;  1UDY A; 
#chains in the Genus database with same CATH topology
 4ZXV A;  1JM6 A;  1XFU A;  4L3X A;  3SXQ A;  2E0A A;  1FS7 A;  3CRK A;  4Q4U A;  1FS9 A;  2ZO5 A;  3UU9 A;  2CJ5 A;  1GJV A;  2ZKJ A;  3F29 A;  5K3I A;  4Q5B A;  4LQQ B;  4G97 A;  3R7K A;  3U33 A;  4V25 A;  3TZ4 A;  3EOM A;  2BU2 A;  3SF6 A;  2YYK A;  3GQT A;  3D6B A;  5J6A A;  3B96 A;  1K90 A;  1RP3 A;  2YYG A;  2CJ6 A;  3X0X A;  2OEX A;  4KSF A;  2C0U A;  3MKH A;  2LFW A;  1R2J A;  3SCE A;  4E02 A;  3OWM A;  3TZ5 A;  2PNR A;  2EBF X;  4X28 A;  2Q8G A;  2WBI A;  4F0X A;  1T9G A;  2ZDX A;  3MPJ A;  5BRM A;  4M9A A;  2CX9 A;  4HKR A;  4Q17 A;  4NXL A;  2BU6 A;  2F6L A;  4IRN A;  5K3H A;  2FON A;  1XFZ A;  1GKZ A;  2OJQ A;  2A1T A;  2QR4 A;  2AO2 A;  4RM7 A;  1FS8 A;  2YYI A;  4L1F A;  4W9U A;  4J1V A;  5B6B A;  3TZ2 A;  2VIG A;  4AKG A;  3N0R A;  4ZYJ A;  1W07 A;  4FF2 A;  3D9F A;  2VR0 A;  2J7A A;  2UXW A;  2YYM A;  4X28 C;  3CRL A;  3KML A;  5M4M A;  2CJ4 A;  2GBB A;  3OIB A;  3MPI A;  2CJ7 A;  4Q5C A;  4E01 A;  2OR0 A;  1PI1 A;  4KCF A;  3AFE A;  3TTB A;  3OWA A;  3X0Y A;  3Q23 A;  3M9V A;  1K8T A;  2OEV A;  4G5E A;  4H81 A;  2BTZ A;  4L38 A;  5GJW E;  4MPC A;  3C2P A;  2E81 A;  2PO4 A;  1IVH A;  4DOY A;  4HR3 A;  4P13 A;  5B5W A;  4HKS A;  1LVC A;  4U83 A;  2JBT A;  5M4K A;  4L3Y A;  4O5M A;  4JIZ A;  2Z1Q A;  2RFQ A;  4OO2 A;  3D9G A;  4FF4 A;  4V26 A;  4MP7 A;  3FO3 A;  1IS2 A;  2ZAF A;  1RX0 A;  2JBS A;  1EGC A;  1EGE A;  2YYL A;  4KSA A;  4AKH A;  5J71 A;  2EC5 A;  3VKH A;  4FF3 A;  3AFF A;  5BRK A;  2XQR B;  3BNF A;  4LQS B;  2JIF A;  2XS8 A;  2OT4 A;  5M4P A;  3Q24 A;  2C12 A;  3GM6 A;  2IX6 A;  5K3J A;  1XFX A;  1WS9 A;  1Y8P A;  4Q1O A;  2D29 A;  2RF7 A;  3HWC A;  4MP2 A;  2Q8H A;  3II9 A;  3FCJ A;  4MPN A;  5GJV E;  1OAH A;  1S26 A;  3NF4 A;  2XS1 A;  3D9E A;  3P4T A;  2CJ8 A;  3MXL A;  3MMO A;  4H7Q A;  1QDB A;  3LG1 A;  3MDD A;  2HJN A;  5EZ3 A;  1SIR A;  1UKW A;  2REH A;  1XG2 B;  2Q8F A;  2FP1 A;  3BNJ A;  1U8V A;  3TZ0 A;  3CE2 A;  1EGD A;  2ZDY A;  2R0M A;  1Y0V A;  4QIC A;  3C3L A;  1XFV A;  2BU5 A;  2JBR A;  4H85 A;  1BUC A;  5K3G A;  1Y8N A;  3EON A;  2BU7 A;  3D2R A;  2R0N A;  1X91 A;  2BU8 A;  2YGW A;  1RJ4 A;  2EBH X;  4P79 A;  3GNC A;  3BNG A;  4WJY A;  1GU6 A;  2Q8I A;  3VAD A;  4XVX A;  1RJ1 A;  2EBA A;  2R02 A;  3MDE A;  4AI6 A;  3TOR A;  3S7W A;  3BNH A;  3DJL A;  3L1T A;  2AZE A;  4L3Z A;  5B5V A;  3UBR A;  3Q22 A;  2FP2 A;  4DZY A;  1XFW A;  2PG0 A;  3D9D A;  2R05 A;  4FF1 A;  3LGQ A;  2RDZ A;  1SIQ A;  4JEK A;  4E00 A;  3X29 A;  1JQI A;  1X90 A;  4KTO A;  2IX5 A;  2DVL A;  1K93 A;  2YYJ A;  4IV6 A;  1R3B A;  4Q0T A;  2VF1 A;  1SK6 A;  2DDH A;  1GKX A;  1PK0 A;  1SC5 A;  2E80 A;  3RKH A;  3Q0A A;  1Y8O A;  1X8Z A;  3D1I A;  3PFD A;  4JIO A;  1XFY A;  4AKI A;  3VKG A;  4FZ4 A;  4MPE A;  4N5F A;  4KS9 A;  3C46 A;  3SWO A;  2R03 A;  1UDY A;  5M4N A; 
#chains in the Genus database with same CATH homology
 4ZXV A;  4L3X A;  3SXQ A;  1FS7 A;  4Q4U A;  1FS9 A;  2ZO5 A;  3UU9 A;  3F29 A;  5K3I A;  4Q5B A;  3R7K A;  3EOM A;  3SF6 A;  2YYK A;  3GQT A;  3D6B A;  3B96 A;  2YYG A;  3X0X A;  2C0U A;  3MKH A;  1R2J A;  3SCE A;  3OWM A;  4X28 A;  2WBI A;  1T9G A;  3MPJ A;  4M9A A;  2CX9 A;  4Q17 A;  4NXL A;  4IRN A;  5K3H A;  2FON A;  2A1T A;  4RM7 A;  1FS8 A;  2YYI A;  4L1F A;  4W9U A;  2VIG A;  4ZYJ A;  1W07 A;  3D9F A;  2VR0 A;  2J7A A;  2UXW A;  2YYM A;  4X28 C;  4Q5C A;  3OIB A;  3MPI A;  2OR0 A;  4KCF A;  3AFE A;  3TTB A;  3OWA A;  3X0Y A;  3M9V A;  4G5E A;  4L38 A;  2E81 A;  1IVH A;  4DOY A;  4HR3 A;  4P13 A;  4U83 A;  2JBT A;  4L3Y A;  4O5M A;  2Z1Q A;  2RFQ A;  4OO2 A;  3D9G A;  3FO3 A;  1IS2 A;  2ZAF A;  1RX0 A;  2JBS A;  1EGC A;  1EGE A;  2YYL A;  3AFF A;  3BNF A;  2JIF A;  2OT4 A;  2C12 A;  3GM6 A;  2IX6 A;  5K3J A;  1WS9 A;  4Q1O A;  2D29 A;  2RF7 A;  3HWC A;  3II9 A;  3FCJ A;  1OAH A;  3NF4 A;  3D9E A;  3P4T A;  3MXL A;  3MMO A;  1QDB A;  3LG1 A;  3MDD A;  1SIR A;  1UKW A;  2REH A;  3BNJ A;  1U8V A;  1EGD A;  2R0M A;  2JBR A;  1BUC A;  5K3G A;  3EON A;  2R0N A;  3GNC A;  3BNG A;  4WJY A;  1GU6 A;  4XVX A;  2EBA A;  3MDE A;  3TOR A;  3S7W A;  3BNH A;  3L1T A;  4L3Z A;  3UBR A;  2PG0 A;  3D9D A;  3LGQ A;  2RDZ A;  1SIQ A;  4JEK A;  1JQI A;  4KTO A;  2IX5 A;  2DVL A;  2YYJ A;  4IV6 A;  4Q0T A;  2DDH A;  2E80 A;  3RKH A;  3D1I A;  3PFD A;  4N5F A;  3SWO A;  1UDY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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