4HR3A

Structure of a putative acyl-coa dehydrogenase from mycobacterium abscessus
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
407
structure length
407
Chain Sequence
FAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELDSLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium abscessus
molecule keywords Putative acyl-CoA dehydrogenase
total genus 145
structure length 407
sequence length 407
ec nomenclature
pdb deposition date 2012-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4hr3A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4hr3A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4hr3A02
3X0XA 3SXQA 1WS9A 4Q0TA 3F29A 3D9FA 4Q5BA 3MPJA 5K3IA 2RDZA 2JBSA 2FONA 3P4TA 2A1TA 3M9VA 4P13A 2E80A 3SF6A 2YYIA 1UDYA 4KCFA 3AFEA 3BNFA 4ZXVA 5K3JA 2D29A 3R7KA 1R2JA 4XVXA 4KTOA 4DOYA 4L1FA 1SIRA 3S7WA 1IVHA 4IV6A 2YYLA 2DDHA 1EGEA 4X28C 2YYJA 4JEKA 4X28A 1JQIA 4OO2A 3TTBA 4Q17A 4RM7A 4U83A 3MDEA 3AFFA 4L3ZA 1OAHA 1GU6A 2Z1QA 3EONA 3GQTA 2YYKA 1U8VA 3NF4A 3EOMA 5K3GA 2C12A 4L3YA 3SCEA 3BNGA 2JIFA 3D9EA 4M9AA 4ZYJA 4L38A 3D6BA 2JBRA 2REHA 4IRNA 1T9GA 2RFQA 3SWOA 3GM6A 2WBIA 3L1TA 3MDDA 1QDBA 3BNJA 1W07A 4NXLA 5K3HA 3LG1A 2OT4A 2ZAFA 2ZO5A 2YYMA 2PG0A 4Q5CA 1IS2A 2CX9A 2EBAA 2IX5A 2VIGA 3GNCA 1FS8A 2VR0A 3D1IA 2JBTA 3B96A 2UXWA 2R0MA 4Q1OA 2IX6A 3II9A 1FS7A 3MMOA 4N5FA 2RF7A 4Q4UA 3D9DA 4O5MA 3FCJA 1UKWA 3HWCA 1FS9A 2J7AA 4L3XA 3PFDA 1EGDA 3RKHA 3TORA 3UBRA 3FO3A 3OWAA 2OR0A 3X0YA 3D9GA 3LGQA 4WJYA 1RX0A 3OIBA 4G5EA 3MKHA 3OWMA 1SIQA 3UU9A 1EGCA 3BNHA 2C0UA 2E81A 4HR3A 2DVLA 4W9UA 2YYGA 3MXLA 3MPIA 1BUCA 2R0NA
chains in the Genus database with same CATH superfamily
3X0XA 4LQSB 3SXQA 2PNRA 2GBBA 2BU7A 2Q8IA 1WS9A 4Q0TA 2Q8HA 3TZ0A 3F29A 4E02A 3D9FA 2VF1A 4Q5BA 3C3LA 3MPJA 5K3IA 1XG2B 1Y8NA 2RDZA 2JBSA 4AKHA 2FONA 3P4TA 2CJ6A 2CJ7A 2A1TA 3M9VA 4P13A 1XFYA 4AKGA 4AI6A 2E80A 3VKHA 3SF6A 2YYIA 1UDYA 2BU8A 4H85A 2CJ8A 4KCFA 3AFEA 3Q22A 2CJ4A 3BNFA 4FF1A 4ZXVA 5K3JA 2OJQA 2D29A 2HJNA 2R02A 3R7KA 1R2JA 1XFUA 4HKSA 4DZYA 4XVXA 1RP3A 1X91A 4KTOA 3KMLA 4MPNA 4FF3A 4AKIA 2R03A 5BRMA 3TZ4A 4DOYA 4P79A 1GKZA 2YGWA 4L1FA 1SIRA 5B5VA 1IVHA 5GJVE 3S7WA 5M4PA 5EZ3A 4IV6A 2YYLA 4H7QA 3VADA 2DDHA 2Q8GA 1EGEA 4X28C 2YYJA 4JEKA 4X28A 4KS9A 2BU6A 1XFXA 4FZ4A 2XS8A 1JQIA 3D2RA 4E00A 4OO2A 1PI1A 4Q17A 3TTBA 4RM7A 4V26A 4U83A 3MDEA 3AFFA 1SK6A 1LVCA 1XFZA 4MPEA 2E0AA 4L3ZA 1OAHA 1GU6A 2Z1QA 3EONA 3GQTA 3CRLA 1Y8PA 2YYKA 1U8VA 5M4NA 3NF4A 3VKGA 3EOMA 5K3GA 2C12A 1GJVA 1X8ZA 4L3YA 2OEVA 3SCEA 4FF4A 1PK0A 2XS1A 2QR4A 2EBHX 5J71A 3BNGA 5B5WA 3TZ2A 2Q8FA 2JIFA 3D9EA 2FP1A 4M9AA 4ZYJA 1JM6A 4L38A 5M4KA 3C46A 3DJLA 3D6BA 3CRKA 5GJWE 4JIOA 2JBRA 2REHA 4IRNA 2BU5A 2CJ5A 1T9GA 4KSFA 2RFQA 3SWOA 3GM6A 2WBIA 3Q0AA 3L1TA 3MDDA 1QDBA 3BNJA 4E01A 1XFVA 1W07A 4NXLA 5K3HA 5B6BA 3LG1A 2OT4A 2ZAFA 2AZEA 2ZDYA 2ZO5A 2YYMA 2PG0A 4Q5CA 1IS2A 3U33A 2CX9A 2EBAA 2IX5A 2VIGA 3GNCA 1FS8A 2VR0A 3C2PA 3D1IA 2JBTA 3B96A 3CE2A 1Y0VA 2UXWA 3N0RA 2R0MA 4H81A 4Q1OA 2FP2A 1SC5A 2IX6A 3Q23A 3II9A 1GKXA 1FS7A 3MMOA 4N5FA 1RJ4A 2RF7A 4Q4UA 3Q24A 2EBFX 3D9DA 4O5MA 2BTZA 3FCJA 1UKWA 1K93A 1X90A 2OEXA 1FS9A 2J7AA 3HWCA 4HKRA 4L3XA 3PFDA 1EGDA 2ZDXA 3RKHA 3TORA 3UBRA 2ZKJA 4J1VA 3FO3A 3OWAA 2OR0A 3X0YA 3D9GA 3LGQA 4WJYA 2PO4A 4G97A 1RX0A 2EC5A 3OIBA 2XQRB 3TZ5A 1Y8OA 1RJ1A 4KSAA 4G5EA 5J6AA 3MKHA 3OWMA 1SIQA 4V25A 4MPCA 1K90A 5M4MA 4FF2A 1S26A 2R05A 4JIZA 4MP7A 4LQQB 3UU9A 4F0XA 1EGCA 2AO2A 3BNHA 3X29A 2C0UA 2F6LA 1XFWA 2E81A 2LFWA 4MP2A 4HR3A 2DVLA 4W9UA 1R3BA 4QICA 1K8TA 2YYGA 2BU2A 5BRKA 3MXLA 3MPIA 1BUCA 2R0NA
chains in the Genus database with same CATH topology
3X0XA 3SXQA 1WS9A 4Q0TA 3F29A 3D9FA 4Q5BA 3MPJA 5K3IA 2RDZA 2JBSA 2FONA 3P4TA 2A1TA 3M9VA 4P13A 2E80A 3SF6A 2YYIA 1UDYA 4KCFA 3AFEA 3BNFA 4ZXVA 5K3JA 2D29A 3R7KA 1R2JA 4XVXA 4KTOA 4DOYA 4L1FA 1SIRA 3S7WA 1IVHA 4IV6A 2YYLA 2DDHA 1EGEA 4X28C 2YYJA 4JEKA 4X28A 1JQIA 4OO2A 3TTBA 4Q17A 4RM7A 4U83A 3MDEA 3AFFA 4L3ZA 1OAHA 1GU6A 2Z1QA 3EONA 3GQTA 2YYKA 1U8VA 3NF4A 3EOMA 5K3GA 2C12A 4L3YA 3SCEA 3BNGA 2JIFA 3D9EA 4M9AA 4ZYJA 4L38A 3D6BA 2JBRA 2REHA 4IRNA 1T9GA 2RFQA 3SWOA 3GM6A 2WBIA 3L1TA 3MDDA 1QDBA 3BNJA 1W07A 4NXLA 5K3HA 3LG1A 2OT4A 2ZAFA 2ZO5A 2YYMA 2PG0A 4Q5CA 1IS2A 2CX9A 2EBAA 2IX5A 2VIGA 3GNCA 1FS8A 2VR0A 3D1IA 2JBTA 3B96A 2UXWA 2R0MA 4Q1OA 2IX6A 3II9A 1FS7A 3MMOA 4N5FA 2RF7A 4Q4UA 3D9DA 4O5MA 3FCJA 1UKWA 3HWCA 1FS9A 2J7AA 4L3XA 3PFDA 1EGDA 3RKHA 3TORA 3UBRA 3FO3A 3OWAA 2OR0A 3X0YA 3D9GA 3LGQA 4WJYA 1RX0A 3OIBA 4G5EA 3MKHA 3OWMA 1SIQA 3UU9A 1EGCA 3BNHA 2C0UA 2E81A 4HR3A 2DVLA 4W9UA 2YYGA 3MXLA 3MPIA 1BUCA 2R0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X0X A;  3SXQ A;  1WS9 A;  4Q0T A;  3F29 A;  3D9F A;  4Q5B A;  3MPJ A;  5K3I A;  2RDZ A;  2JBS A;  2FON A;  3P4T A;  2A1T A;  3M9V A;  4P13 A;  2E80 A;  3SF6 A;  2YYI A;  1UDY A;  4KCF A;  3AFE A;  3BNF A;  4ZXV A;  5K3J A;  2D29 A;  3R7K A;  1R2J A;  4XVX A;  4KTO A;  4DOY A;  4L1F A;  1SIR A;  3S7W A;  1IVH A;  4IV6 A;  2YYL A;  2DDH A;  1EGE A;  4X28 C;  2YYJ A;  4JEK A;  4X28 A;  1JQI A;  4OO2 A;  3TTB A;  4Q17 A;  4RM7 A;  4U83 A;  3MDE A;  3AFF A;  4L3Z A;  1OAH A;  1GU6 A;  2Z1Q A;  3EON A;  3GQT A;  2YYK A;  1U8V A;  3NF4 A;  3EOM A;  5K3G A;  2C12 A;  4L3Y A;  3SCE A;  3BNG A;  2JIF A;  3D9E A;  4M9A A;  4ZYJ A;  4L38 A;  3D6B A;  2JBR A;  2REH A;  4IRN A;  1T9G A;  2RFQ A;  3SWO A;  3GM6 A;  2WBI A;  3L1T A;  3MDD A;  1QDB A;  3BNJ A;  1W07 A;  4NXL A;  5K3H A;  3LG1 A;  2OT4 A;  2ZAF A;  2ZO5 A;  2YYM A;  2PG0 A;  4Q5C A;  1IS2 A;  2CX9 A;  2EBA A;  2IX5 A;  2VIG A;  3GNC A;  1FS8 A;  2VR0 A;  3D1I A;  2JBT A;  3B96 A;  2UXW A;  2R0M A;  4Q1O A;  2IX6 A;  3II9 A;  1FS7 A;  3MMO A;  4N5F A;  2RF7 A;  4Q4U A;  3D9D A;  4O5M A;  3FCJ A;  1UKW A;  3HWC A;  1FS9 A;  2J7A A;  4L3X A;  3PFD A;  1EGD A;  3RKH A;  3TOR A;  3UBR A;  3FO3 A;  3OWA A;  2OR0 A;  3X0Y A;  3D9G A;  3LGQ A;  4WJY A;  1RX0 A;  3OIB A;  4G5E A;  3MKH A;  3OWM A;  1SIQ A;  3UU9 A;  1EGC A;  3BNH A;  2C0U A;  2E81 A;  4HR3 A;  2DVL A;  4W9U A;  2YYG A;  3MXL A;  3MPI A;  1BUC A;  2R0N A; 
#chains in the Genus database with same CATH topology
 3X0X A;  4LQS B;  3SXQ A;  2PNR A;  2GBB A;  2BU7 A;  2Q8I A;  1WS9 A;  4Q0T A;  2Q8H A;  3TZ0 A;  3F29 A;  4E02 A;  3D9F A;  2VF1 A;  4Q5B A;  3C3L A;  3MPJ A;  5K3I A;  1XG2 B;  1Y8N A;  2RDZ A;  2JBS A;  4AKH A;  2FON A;  3P4T A;  2CJ6 A;  2CJ7 A;  2A1T A;  3M9V A;  4P13 A;  1XFY A;  4AKG A;  4AI6 A;  2E80 A;  3VKH A;  3SF6 A;  2YYI A;  1UDY A;  2BU8 A;  4H85 A;  2CJ8 A;  4KCF A;  3AFE A;  3Q22 A;  2CJ4 A;  3BNF A;  4FF1 A;  4ZXV A;  5K3J A;  2OJQ A;  2D29 A;  2HJN A;  2R02 A;  3R7K A;  1R2J A;  1XFU A;  4HKS A;  4DZY A;  4XVX A;  1RP3 A;  1X91 A;  4KTO A;  3KML A;  4MPN A;  4FF3 A;  4AKI A;  2R03 A;  5BRM A;  3TZ4 A;  4DOY A;  4P79 A;  1GKZ A;  2YGW A;  4L1F A;  1SIR A;  5B5V A;  1IVH A;  5GJV E;  3S7W A;  5M4P A;  5EZ3 A;  4IV6 A;  2YYL A;  4H7Q A;  3VAD A;  2DDH A;  2Q8G A;  1EGE A;  4X28 C;  2YYJ A;  4JEK A;  4X28 A;  4KS9 A;  2BU6 A;  1XFX A;  4FZ4 A;  2XS8 A;  1JQI A;  3D2R A;  4E00 A;  4OO2 A;  1PI1 A;  4Q17 A;  3TTB A;  4RM7 A;  4V26 A;  4U83 A;  3MDE A;  3AFF A;  1SK6 A;  1LVC A;  1XFZ A;  4MPE A;  2E0A A;  4L3Z A;  1OAH A;  1GU6 A;  2Z1Q A;  3EON A;  3GQT A;  3CRL A;  1Y8P A;  2YYK A;  1U8V A;  5M4N A;  3NF4 A;  3VKG A;  3EOM A;  5K3G A;  2C12 A;  1GJV A;  1X8Z A;  4L3Y A;  2OEV A;  3SCE A;  4FF4 A;  1PK0 A;  2XS1 A;  2QR4 A;  2EBH X;  5J71 A;  3BNG A;  5B5W A;  3TZ2 A;  2Q8F A;  2JIF A;  3D9E A;  2FP1 A;  4M9A A;  4ZYJ A;  1JM6 A;  4L38 A;  5M4K A;  3C46 A;  3DJL A;  3D6B A;  3CRK A;  5GJW E;  4JIO A;  2JBR A;  2REH A;  4IRN A;  2BU5 A;  2CJ5 A;  1T9G A;  4KSF A;  2RFQ A;  3SWO A;  3GM6 A;  2WBI A;  3Q0A A;  3L1T A;  3MDD A;  1QDB A;  3BNJ A;  4E01 A;  1XFV A;  1W07 A;  4NXL A;  5K3H A;  5B6B A;  3LG1 A;  2OT4 A;  2ZAF A;  2AZE A;  2ZDY A;  2ZO5 A;  2YYM A;  2PG0 A;  4Q5C A;  1IS2 A;  3U33 A;  2CX9 A;  2EBA A;  2IX5 A;  2VIG A;  3GNC A;  1FS8 A;  2VR0 A;  3C2P A;  3D1I A;  2JBT A;  3B96 A;  3CE2 A;  1Y0V A;  2UXW A;  3N0R A;  2R0M A;  4H81 A;  4Q1O A;  2FP2 A;  1SC5 A;  2IX6 A;  3Q23 A;  3II9 A;  1GKX A;  1FS7 A;  3MMO A;  4N5F A;  1RJ4 A;  2RF7 A;  4Q4U A;  3Q24 A;  2EBF X;  3D9D A;  4O5M A;  2BTZ A;  3FCJ A;  1UKW A;  1K93 A;  1X90 A;  2OEX A;  1FS9 A;  2J7A A;  3HWC A;  4HKR A;  4L3X A;  3PFD A;  1EGD A;  2ZDX A;  3RKH A;  3TOR A;  3UBR A;  2ZKJ A;  4J1V A;  3FO3 A;  3OWA A;  2OR0 A;  3X0Y A;  3D9G A;  3LGQ A;  4WJY A;  2PO4 A;  4G97 A;  1RX0 A;  2EC5 A;  3OIB A;  2XQR B;  3TZ5 A;  1Y8O A;  1RJ1 A;  4KSA A;  4G5E A;  5J6A A;  3MKH A;  3OWM A;  1SIQ A;  4V25 A;  4MPC A;  1K90 A;  5M4M A;  4FF2 A;  1S26 A;  2R05 A;  4JIZ A;  4MP7 A;  4LQQ B;  3UU9 A;  4F0X A;  1EGC A;  2AO2 A;  3BNH A;  3X29 A;  2C0U A;  2F6L A;  1XFW A;  2E81 A;  2LFW A;  4MP2 A;  4HR3 A;  2DVL A;  4W9U A;  1R3B A;  4QIC A;  1K8T A;  2YYG A;  2BU2 A;  5BRK A;  3MXL A;  3MPI A;  1BUC A;  2R0N A; 
#chains in the Genus database with same CATH homology
 3X0X A;  3SXQ A;  1WS9 A;  4Q0T A;  3F29 A;  3D9F A;  4Q5B A;  3MPJ A;  5K3I A;  2RDZ A;  2JBS A;  2FON A;  3P4T A;  2A1T A;  3M9V A;  4P13 A;  2E80 A;  3SF6 A;  2YYI A;  1UDY A;  4KCF A;  3AFE A;  3BNF A;  4ZXV A;  5K3J A;  2D29 A;  3R7K A;  1R2J A;  4XVX A;  4KTO A;  4DOY A;  4L1F A;  1SIR A;  3S7W A;  1IVH A;  4IV6 A;  2YYL A;  2DDH A;  1EGE A;  4X28 C;  2YYJ A;  4JEK A;  4X28 A;  1JQI A;  4OO2 A;  3TTB A;  4Q17 A;  4RM7 A;  4U83 A;  3MDE A;  3AFF A;  4L3Z A;  1OAH A;  1GU6 A;  2Z1Q A;  3EON A;  3GQT A;  2YYK A;  1U8V A;  3NF4 A;  3EOM A;  5K3G A;  2C12 A;  4L3Y A;  3SCE A;  3BNG A;  2JIF A;  3D9E A;  4M9A A;  4ZYJ A;  4L38 A;  3D6B A;  2JBR A;  2REH A;  4IRN A;  1T9G A;  2RFQ A;  3SWO A;  3GM6 A;  2WBI A;  3L1T A;  3MDD A;  1QDB A;  3BNJ A;  1W07 A;  4NXL A;  5K3H A;  3LG1 A;  2OT4 A;  2ZAF A;  2ZO5 A;  2YYM A;  2PG0 A;  4Q5C A;  1IS2 A;  2CX9 A;  2EBA A;  2IX5 A;  2VIG A;  3GNC A;  1FS8 A;  2VR0 A;  3D1I A;  2JBT A;  3B96 A;  2UXW A;  2R0M A;  4Q1O A;  2IX6 A;  3II9 A;  1FS7 A;  3MMO A;  4N5F A;  2RF7 A;  4Q4U A;  3D9D A;  4O5M A;  3FCJ A;  1UKW A;  3HWC A;  1FS9 A;  2J7A A;  4L3X A;  3PFD A;  1EGD A;  3RKH A;  3TOR A;  3UBR A;  3FO3 A;  3OWA A;  2OR0 A;  3X0Y A;  3D9G A;  3LGQ A;  4WJY A;  1RX0 A;  3OIB A;  4G5E A;  3MKH A;  3OWM A;  1SIQ A;  3UU9 A;  1EGC A;  3BNH A;  2C0U A;  2E81 A;  4HR3 A;  2DVL A;  4W9U A;  2YYG A;  3MXL A;  3MPI A;  1BUC A;  2R0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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