4IV6 | Genus

Total Genus 150

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	150
sequence length	382
structure length	382
Chain Sequence	LTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAVSMPCYVQVAEELARGWMSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRATMALTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKGVSILLVEKVPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGLEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLLLSAAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPLMIVGEGTNEIQRNVIAKQLVARGGLDI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 382 atoms

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382 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxidoreductase
source organism	Mycobacterium smegmatis
publication title	Increasing the structural coverage of tuberculosis drug targets. pubmed doi rcsb
molecule keywords	Acyl-CoA dehydrogenase FadE3
total genus	150
structure length	382
sequence length	382
chains with identical sequence	B
ec nomenclature	ec 1.3.8.1: Short-chain acyl-CoA dehydrogenase.
pdb deposition date	2013-01-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00441	Acyl-CoA_dh_1	Acyl-CoA dehydrogenase, C-terminal domain
A	PF02770	Acyl-CoA_dh_M	Acyl-CoA dehydrogenase, middle domain
A	PF02771	Acyl-CoA_dh_N	Acyl-CoA dehydrogenase, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A; domain 1	Acyl-CoA dehydrogenase/oxidase, N-terminal domain	4iv6A01
1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A, domain 3	4iv6A03
2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A; domain 2	Butyryl-CoA Dehydrogenase, subunit A, domain 2	4iv6A02

4HR3A 3F29A 4L3XA 3GNCA 1QDBA 3UBRA 3MPIA 2DVLA 1WS9A 4XVXA 1UDYA 3PFDA 3RKHA 3SCEA 1GU6A 3GM6A 2REHA 2UXWA 4OO2A 3GQTA 1SIQA 2OR0A 2WBIA 2D29A 3LG1A 4Q5BA 4IRNA 4W9UA 1RX0A 4N5FA 3MDEA 2JBSA 2YYIA 4WJYA 4X28A 4Q5CA 4ZYJA 2A1TA 3AFFA 4L38A 2OT4A 2YYKA 3BNHA 3BNGA 1JQIA 4M9AA 2ZO5A 2CX9A 3II9A 1IVHA 3P4TA 2JBTA 3R7KA 1U8VA 1EGCA 2IX5A 2DDHA 2EBAA 2PG0A 3HWCA 4DOYA 3NF4A 4Q4UA 1UKWA 3UU9A 4L3YA 3L1TA 2IX6A 3MXLA 4ZXVA 2C12A 2R0NA 2YYJA 3D9GA 3BNFA 1W07A 3OIBA 4JEKA 2ZAFA 4G5EA 2Z1QA 5K3IA 4Q17A 3BNJA 3D9EA 3OWAA 3LGQA 3AFEA 4NXLA 4X28C 3D9DA 1FS8A 5K3GA 4RM7A 1BUCA 4KCFA 3D1IA 2RF7A 1EGEA 1T9GA 4L1FA 1EGDA 4Q0TA 1IS2A 5K3HA 2RDZA 2JBRA 2VIGA 3EOMA 3MKHA 4L3ZA 4Q1OA 2J7AA 3MPJA 4P13A 1FS9A 3OWMA 3SWOA 1OAHA 4O5MA 2FONA 2JIFA 2C0UA 3X0XA 3D9FA 2VR0A 3X0YA 1R2JA 1FS7A 2E80A 3FO3A 3FCJA 1SIRA 2E81A 3SXQA 4IV6A 3TORA 3B96A 2YYMA 3MDDA 3MMOA 2YYGA 3EONA 3S7WA 4KTOA 3M9VA 4U83A 3D6BA 2YYLA 3TTBA 2RFQA 2R0MA 3SF6A 5K3JA
chains in the Genus database with same CATH superfamily

1RJ4A 2YGWA 2BU8A 4J1VA 2VF1A 4HR3A 3F29A 4KS9A 4KSFA 3VKGA 4L3XA 2Q8IA 3CE2A 3C46A 3GNCA 1QDBA 3UBRA 3MPIA 2DVLA 1GKXA 1WS9A 4XVXA 4AI6A 1UDYA 3PFDA 3RKHA 3SCEA 1GJVA 1GU6A 3GM6A 2REHA 2UXWA 2CJ8A 4H85A 4OO2A 3GQTA 1SIQA 1Y8OA 2OR0A 2BU5A 2XQRB 4V26A 2WBIA 2D29A 2OJQA 4MP7A 3LG1A 4Q5BA 3TZ4A 4IRNA 4W9UA 3TZ2A 4E00A 2Q8HA 2PO4A 1RX0A 4P79A 3X29A 1X90A 4FF1A 4N5FA 2Q8FA 2BU2A 3MDEA 2JBSA 2YYIA 3Q0AA 4WJYA 4X28A 1RJ1A 4JIOA 4Q5CA 4ZYJA 3C2PA 2A1TA 5B6BA 4E01A 1X91A 3AFFA 1XFXA 4L38A 2AZEA 4V25A 2OT4A 5BRKA 5J71A 2YYKA 3BNHA 3BNGA 1JQIA 4M9AA 2ZO5A 2CX9A 3II9A 1IVHA 3P4TA 2JBTA 3R7KA 1U8VA 3D2RA 2BU6A 1EGCA 2FP2A 2IX5A 2DDHA 4FZ4A 3Q24A 3DJLA 3N0RA 2EBAA 2PG0A 1Y0VA 2EC5A 4DOYA 3HWCA 3NF4A 1XFVA 1S26A 2CJ7A 3C3LA 1GKZA 4Q4UA 1UKWA 2QR4A 3Q22A 3UU9A 2BU7A 4L3YA 1Y8PA 4AKHA 2CJ5A 3L1TA 2IX6A 3MXLA 4ZXVA 1SC5A 3VADA 2C12A 2R0NA 4FF2A 2YYJA 1X8ZA 3D9GA 3BNFA 1W07A 3OIBA 4FF3A 4JIZA 3TZ0A 4JEKA 2ZAFA 4G5EA 2Z1QA 5K3IA 4Q17A 2GBBA 3BNJA 2R03A 4DZYA 3D9EA 2ZDXA 1PI1A 2HJNA 3OWAA 3LGQA 5M4PA 1SK6A 3AFEA 1R3BA 1XFYA 4NXLA 4X28C 3D9DA 1K90A 1FS8A 4KSAA 4MP2A 5K3GA 1PK0A 4RM7A 2EBHX 5B5WA 2R05A 2LFWA 1BUCA 4QICA 5J6AA 4KCFA 3D1IA 2RF7A 1EGEA 2AO2A 1T9GA 4L1FA 5BRMA 5M4KA 1EGDA 3Q23A 3TZ5A 4Q0TA 1IS2A 1XFUA 5K3HA 2RDZA 2JBRA 2XS1A 4AKGA 2VIGA 2EBFX 3EOMA 3U33A 3MKHA 1XFZA 4MPCA 4L3ZA 2ZKJA 4Q1OA 2J7AA 4HKSA 2E0AA 3MPJA 4P13A 1FS9A 3OWMA 4H81A 3SWOA 1K8TA 1OAHA 4AKIA 4O5MA 2FONA 2JIFA 4G97A 1Y8NA 2CJ4A 2C0UA 3X0XA 3D9FA 2VR0A 2BTZA 3X0YA 1LVCA 3CRLA 1R2JA 1FS7A 2E80A 3FO3A 4LQQB 3FCJA 1SIRA 5GJWE 2Q8GA 3VKHA 4HKRA 2E81A 4MPNA 3SXQA 4IV6A 5M4NA 3TORA 3KMLA 4F0XA 3B96A 2FP1A 2ZDYA 2YYMA 2F6LA 4MPEA 5GJVE 5B5VA 2CJ6A 3MDDA 3CRKA 3MMOA 2YYGA 3EONA 4H7QA 4KTOA 3S7WA 2R02A 2OEVA 3M9VA 4E02A 4FF4A 4U83A 1XFWA 1XG2B 5M4MA 3D6BA 2YYLA 1JM6A 3TTBA 2OEXA 2XS8A 2RFQA 5EZ3A 1K93A 4LQSB 1RP3A 2PNRA 2R0MA 3SF6A 5K3JA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4HR3 A;  3F29 A;  4L3X A;  3GNC A;  1QDB A;  3UBR A;  3MPI A;  2DVL A;  1WS9 A;  4XVX A;  1UDY A;  3PFD A;  3RKH A;  3SCE A;  1GU6 A;  3GM6 A;  2REH A;  2UXW A;  4OO2 A;  3GQT A;  1SIQ A;  2OR0 A;  2WBI A;  2D29 A;  3LG1 A;  4Q5B A;  4IRN A;  4W9U A;  1RX0 A;  4N5F A;  3MDE A;  2JBS A;  2YYI A;  4WJY A;  4X28 A;  4Q5C A;  4ZYJ A;  2A1T A;  3AFF A;  4L38 A;  2OT4 A;  2YYK A;  3BNH A;  3BNG A;  1JQI A;  4M9A A;  2ZO5 A;  2CX9 A;  3II9 A;  1IVH A;  3P4T A;  2JBT A;  3R7K A;  1U8V A;  1EGC A;  2IX5 A;  2DDH A;  2EBA A;  2PG0 A;  3HWC A;  4DOY A;  3NF4 A;  4Q4U A;  1UKW A;  3UU9 A;  4L3Y A;  3L1T A;  2IX6 A;  3MXL A;  4ZXV A;  2C12 A;  2R0N A;  2YYJ A;  3D9G A;  3BNF A;  1W07 A;  3OIB A;  4JEK A;  2ZAF A;  4G5E A;  2Z1Q A;  5K3I A;  4Q17 A;  3BNJ A;  3D9E A;  3OWA A;  3LGQ A;  3AFE A;  4NXL A;  4X28 C;  3D9D A;  1FS8 A;  5K3G A;  4RM7 A;  1BUC A;  4KCF A;  3D1I A;  2RF7 A;  1EGE A;  1T9G A;  4L1F A;  1EGD A;  4Q0T A;  1IS2 A;  5K3H A;  2RDZ A;  2JBR A;  2VIG A;  3EOM A;  3MKH A;  4L3Z A;  4Q1O A;  2J7A A;  3MPJ A;  4P13 A;  1FS9 A;  3OWM A;  3SWO A;  1OAH A;  4O5M A;  2FON A;  2JIF A;  2C0U A;  3X0X A;  3D9F A;  2VR0 A;  3X0Y A;  1R2J A;  1FS7 A;  2E80 A;  3FO3 A;  3FCJ A;  1SIR A;  2E81 A;  3SXQ A;  4IV6 A;  3TOR A;  3B96 A;  2YYM A;  3MDD A;  3MMO A;  2YYG A;  3EON A;  3S7W A;  4KTO A;  3M9V A;  4U83 A;  3D6B A;  2YYL A;  3TTB A;  2RFQ A;  2R0M A;  3SF6 A;  5K3J A; 
#chains in the Genus database with same CATH topology
 1RJ4 A;  2YGW A;  2BU8 A;  4J1V A;  2VF1 A;  4HR3 A;  3F29 A;  4KS9 A;  4KSF A;  3VKG A;  4L3X A;  2Q8I A;  3CE2 A;  3C46 A;  3GNC A;  1QDB A;  3UBR A;  3MPI A;  2DVL A;  1GKX A;  1WS9 A;  4XVX A;  4AI6 A;  1UDY A;  3PFD A;  3RKH A;  3SCE A;  1GJV A;  1GU6 A;  3GM6 A;  2REH A;  2UXW A;  2CJ8 A;  4H85 A;  4OO2 A;  3GQT A;  1SIQ A;  1Y8O A;  2OR0 A;  2BU5 A;  2XQR B;  4V26 A;  2WBI A;  2D29 A;  2OJQ A;  4MP7 A;  3LG1 A;  4Q5B A;  3TZ4 A;  4IRN A;  4W9U A;  3TZ2 A;  4E00 A;  2Q8H A;  2PO4 A;  1RX0 A;  4P79 A;  3X29 A;  1X90 A;  4FF1 A;  4N5F A;  2Q8F A;  2BU2 A;  3MDE A;  2JBS A;  2YYI A;  3Q0A A;  4WJY A;  4X28 A;  1RJ1 A;  4JIO A;  4Q5C A;  4ZYJ A;  3C2P A;  2A1T A;  5B6B A;  4E01 A;  1X91 A;  3AFF A;  1XFX A;  4L38 A;  2AZE A;  4V25 A;  2OT4 A;  5BRK A;  5J71 A;  2YYK A;  3BNH A;  3BNG A;  1JQI A;  4M9A A;  2ZO5 A;  2CX9 A;  3II9 A;  1IVH A;  3P4T A;  2JBT A;  3R7K A;  1U8V A;  3D2R A;  2BU6 A;  1EGC A;  2FP2 A;  2IX5 A;  2DDH A;  4FZ4 A;  3Q24 A;  3DJL A;  3N0R A;  2EBA A;  2PG0 A;  1Y0V A;  2EC5 A;  4DOY A;  3HWC A;  3NF4 A;  1XFV A;  1S26 A;  2CJ7 A;  3C3L A;  1GKZ A;  4Q4U A;  1UKW A;  2QR4 A;  3Q22 A;  3UU9 A;  2BU7 A;  4L3Y A;  1Y8P A;  4AKH A;  2CJ5 A;  3L1T A;  2IX6 A;  3MXL A;  4ZXV A;  1SC5 A;  3VAD A;  2C12 A;  2R0N A;  4FF2 A;  2YYJ A;  1X8Z A;  3D9G A;  3BNF A;  1W07 A;  3OIB A;  4FF3 A;  4JIZ A;  3TZ0 A;  4JEK A;  2ZAF A;  4G5E A;  2Z1Q A;  5K3I A;  4Q17 A;  2GBB A;  3BNJ A;  2R03 A;  4DZY A;  3D9E A;  2ZDX A;  1PI1 A;  2HJN A;  3OWA A;  3LGQ A;  5M4P A;  1SK6 A;  3AFE A;  1R3B A;  1XFY A;  4NXL A;  4X28 C;  3D9D A;  1K90 A;  1FS8 A;  4KSA A;  4MP2 A;  5K3G A;  1PK0 A;  4RM7 A;  2EBH X;  5B5W A;  2R05 A;  2LFW A;  1BUC A;  4QIC A;  5J6A A;  4KCF A;  3D1I A;  2RF7 A;  1EGE A;  2AO2 A;  1T9G A;  4L1F A;  5BRM A;  5M4K A;  1EGD A;  3Q23 A;  3TZ5 A;  4Q0T A;  1IS2 A;  1XFU A;  5K3H A;  2RDZ A;  2JBR A;  2XS1 A;  4AKG A;  2VIG A;  2EBF X;  3EOM A;  3U33 A;  3MKH A;  1XFZ A;  4MPC A;  4L3Z A;  2ZKJ A;  4Q1O A;  2J7A A;  4HKS A;  2E0A A;  3MPJ A;  4P13 A;  1FS9 A;  3OWM A;  4H81 A;  3SWO A;  1K8T A;  1OAH A;  4AKI A;  4O5M A;  2FON A;  2JIF A;  4G97 A;  1Y8N A;  2CJ4 A;  2C0U A;  3X0X A;  3D9F A;  2VR0 A;  2BTZ A;  3X0Y A;  1LVC A;  3CRL A;  1R2J A;  1FS7 A;  2E80 A;  3FO3 A;  4LQQ B;  3FCJ A;  1SIR A;  5GJW E;  2Q8G A;  3VKH A;  4HKR A;  2E81 A;  4MPN A;  3SXQ A;  4IV6 A;  5M4N A;  3TOR A;  3KML A;  4F0X A;  3B96 A;  2FP1 A;  2ZDY A;  2YYM A;  2F6L A;  4MPE A;  5GJV E;  5B5V A;  2CJ6 A;  3MDD A;  3CRK A;  3MMO A;  2YYG A;  3EON A;  4H7Q A;  4KTO A;  3S7W A;  2R02 A;  2OEV A;  3M9V A;  4E02 A;  4FF4 A;  4U83 A;  1XFW A;  1XG2 B;  5M4M A;  3D6B A;  2YYL A;  1JM6 A;  3TTB A;  2OEX A;  2XS8 A;  2RFQ A;  5EZ3 A;  1K93 A;  4LQS B;  1RP3 A;  2PNR A;  2R0M A;  3SF6 A;  5K3J A; 
#chains in the Genus database with same CATH homology
 4HR3 A;  3F29 A;  4L3X A;  3GNC A;  1QDB A;  3UBR A;  3MPI A;  2DVL A;  1WS9 A;  4XVX A;  1UDY A;  3PFD A;  3RKH A;  3SCE A;  1GU6 A;  3GM6 A;  2REH A;  2UXW A;  4OO2 A;  3GQT A;  1SIQ A;  2OR0 A;  2WBI A;  2D29 A;  3LG1 A;  4Q5B A;  4IRN A;  4W9U A;  1RX0 A;  4N5F A;  3MDE A;  2JBS A;  2YYI A;  4WJY A;  4X28 A;  4Q5C A;  4ZYJ A;  2A1T A;  3AFF A;  4L38 A;  2OT4 A;  2YYK A;  3BNH A;  3BNG A;  1JQI A;  4M9A A;  2ZO5 A;  2CX9 A;  3II9 A;  1IVH A;  3P4T A;  2JBT A;  3R7K A;  1U8V A;  1EGC A;  2IX5 A;  2DDH A;  2EBA A;  2PG0 A;  3HWC A;  4DOY A;  3NF4 A;  4Q4U A;  1UKW A;  3UU9 A;  4L3Y A;  3L1T A;  2IX6 A;  3MXL A;  4ZXV A;  2C12 A;  2R0N A;  2YYJ A;  3D9G A;  3BNF A;  1W07 A;  3OIB A;  4JEK A;  2ZAF A;  4G5E A;  2Z1Q A;  5K3I A;  4Q17 A;  3BNJ A;  3D9E A;  3OWA A;  3LGQ A;  3AFE A;  4NXL A;  4X28 C;  3D9D A;  1FS8 A;  5K3G A;  4RM7 A;  1BUC A;  4KCF A;  3D1I A;  2RF7 A;  1EGE A;  1T9G A;  4L1F A;  1EGD A;  4Q0T A;  1IS2 A;  5K3H A;  2RDZ A;  2JBR A;  2VIG A;  3EOM A;  3MKH A;  4L3Z A;  4Q1O A;  2J7A A;  3MPJ A;  4P13 A;  1FS9 A;  3OWM A;  3SWO A;  1OAH A;  4O5M A;  2FON A;  2JIF A;  2C0U A;  3X0X A;  3D9F A;  2VR0 A;  3X0Y A;  1R2J A;  1FS7 A;  2E80 A;  3FO3 A;  3FCJ A;  1SIR A;  2E81 A;  3SXQ A;  4IV6 A;  3TOR A;  3B96 A;  2YYM A;  3MDD A;  3MMO A;  2YYG A;  3EON A;  3S7W A;  4KTO A;  3M9V A;  4U83 A;  3D6B A;  2YYL A;  3TTB A;  2RFQ A;  2R0M A;  3SF6 A;  5K3J A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4IV6A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations