4HR3A

Structure of a putative acyl-coa dehydrogenase from mycobacterium abscessus
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
407
structure length
407
Chain Sequence
FAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELDSLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium abscessus
molecule keywords Putative acyl-CoA dehydrogenase
total genus 145
structure length 407
sequence length 407
ec nomenclature
pdb deposition date 2012-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4hr3A01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4hr3A03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4hr3A02
3D1IA 3OWMA 4L3YA 2FONA 2DVLA 3MPJA 4O5MA 2YYKA 3LGQA 2R0NA 4ZYJA 2OT4A 1FS9A 1IS2A 4KCFA 1RX0A 3AFFA 4Q5BA 2J7AA 3OIBA 1JQIA 3F29A 3GM6A 1FS8A 2E81A 3SCEA 4ZXVA 4NXLA 2WBIA 1W07A 3BNFA 4OO2A 5K3JA 2YYMA 3MDEA 4G5EA 1EGDA 2YYLA 2ZO5A 3OWAA 3L1TA 2IX5A 3D9DA 1UKWA 4U83A 3BNHA 2RF7A 3D9GA 3D9FA 3FCJA 3GNCA 3GQTA 3UU9A 3R7KA 2E80A 3X0YA 2IX6A 2JBSA 4M9AA 3FO3A 4IV6A 3MXLA 3SF6A 3SWOA 3BNGA 1EGCA 3EOMA 4Q1OA 3PFDA 2RDZA 2JBRA 4X28A 3MDDA 1U8VA 3AFEA 2DDHA 2PG0A 2JIFA 2YYIA 4X28C 4IRNA 3P4TA 4Q4UA 4N5FA 2D29A 3BNJA 3TTBA 4DOYA 4Q0TA 2A1TA 1SIRA 1EGEA 2UXWA 2VR0A 4L38A 4JEKA 5K3GA 3MMOA 2YYJA 4L3ZA 5K3HA 4WJYA 2YYGA 3MKHA 2ZAFA 2R0MA 3M9VA 2EBAA 2JBTA 3RKHA 3B96A 1R2JA 3X0XA 4KTOA 4XVXA 1QDBA 2REHA 1T9GA 5K3IA 2C0UA 4HR3A 4W9UA 4P13A 3HWCA 3S7WA 3D9EA 4RM7A 1GU6A 1IVHA 3SXQA 1UDYA 1SIQA 2Z1QA 4Q17A 1BUCA 3D6BA 4L3XA 4L1FA 3LG1A 2RFQA 2OR0A 4Q5CA 3TORA 2C12A 1FS7A 3NF4A 3MPIA 1OAHA 2VIGA 2CX9A 1WS9A 3EONA 3UBRA 3II9A
chains in the Genus database with same CATH superfamily
3C2PA 3D1IA 3OWMA 4H85A 4L3YA 2FONA 2DVLA 3MPJA 4O5MA 2YYKA 3LGQA 3TZ4A 2R0NA 4ZYJA 2OT4A 1FS9A 2BU6A 1IS2A 4KCFA 1S26A 1XFXA 1RX0A 4FF1A 4KSAA 4AKIA 3AFFA 4Q5BA 4FF3A 2BU7A 4KS9A 4F0XA 2J7AA 3OIBA 1SC5A 1JQIA 3F29A 3GM6A 1FS8A 2E81A 2GBBA 1R3BA 3CRLA 4LQSB 4ZXVA 3SCEA 3U33A 3C46A 4NXLA 2WBIA 4P79A 1W07A 2CJ5A 2BU5A 3BNFA 4OO2A 5J6AA 5BRKA 5K3JA 2YYMA 3MDEA 1RP3A 2XS8A 4G5EA 1EGDA 2LFWA 2YYLA 1GKXA 4QICA 2ZO5A 3OWAA 2ZKJA 3L1TA 2IX5A 3D9DA 1UKWA 4U83A 2CJ4A 2Q8FA 3BNHA 2RF7A 3D9GA 3D9FA 3FCJA 3GNCA 3GQTA 2EC5A 3TZ0A 5M4PA 1Y0VA 3KMLA 3UU9A 3Q0AA 1K8TA 4JIZA 2AZEA 3R7KA 2OEXA 2E80A 5B5VA 3X0YA 4MPNA 2IX6A 2JBSA 4M9AA 3FO3A 4IV6A 3MXLA 2FP2A 3SF6A 1XFZA 3SWOA 2BTZA 2YGWA 3VADA 2OEVA 3BNGA 1EGCA 3EOMA 2QR4A 4HKSA 4MP7A 4Q1OA 3PFDA 1Y8OA 2RDZA 3TZ2A 2JBRA 2HJNA 1JM6A 4X28A 2BU2A 4E00A 5M4MA 3UBRA 3MDDA 3DJLA 3Q23A 1U8VA 3AFEA 5M4NA 2XS1A 1X90A 1XFVA 1Y8NA 1K93A 3CRKA 2DDHA 2R05A 2PG0A 2JIFA 2YYIA 2ZDYA 4X28C 4IRNA 2Q8HA 3P4TA 4Q4UA 4N5FA 2D29A 3BNJA 1XFWA 4DOYA 2R02A 2E0AA 4G97A 4Q0TA 2A1TA 1XG2B 1X8ZA 1SIRA 1EGEA 2UXWA 2PNRA 5GJWE 2VR0A 4FF2A 2EBHX 4L38A 4JEKA 5K3GA 3MMOA 3C3LA 2YYJA 4L3ZA 5K3HA 4KSFA 2YYGA 3MKHA 4WJYA 2EBFX 2ZAFA 2R0MA 2Q8GA 3M9VA 4E02A 4H81A 2FP1A 5M4KA 1PK0A 2EBAA 2JBTA 3RKHA 3B96A 4V26A 3VKGA 1R2JA 3X0XA 1X91A 4KTOA 4FF4A 4XVXA 3TTBA 5BRMA 1QDBA 2REHA 5B5WA 1T9GA 1GKZA 5K3IA 2ZDXA 1PI1A 2OJQA 3Q22A 2C0UA 4HR3A 4W9UA 1Y8PA 5J71A 4P13A 2Q8IA 3HWCA 3S7WA 4E01A 1SK6A 2CJ7A 3D9EA 4RM7A 1GU6A 2AO2A 2CJ6A 4AKHA 1IVHA 3CE2A 4MPCA 3SXQA 1UDYA 5B6BA 1XFUA 4MP2A 3TZ5A 5GJVE 1SIQA 2Z1QA 4Q17A 4AKGA 4V25A 1GJVA 1BUCA 3D6BA 1RJ1A 3X29A 4LQQB 4L3XA 4HKRA 3Q24A 4L1FA 3LG1A 3VKHA 2RFQA 2OR0A 4Q5CA 4JIOA 2F6LA 2C12A 3TORA 3D2RA 4FZ4A 4AI6A 4H7QA 3N0RA 1FS7A 3NF4A 1K90A 4J1VA 1RJ4A 2R03A 3MPIA 5EZ3A 1OAHA 2VIGA 2CJ8A 2XQRB 2VF1A 2CX9A 2PO4A 1LVCA 4DZYA 1WS9A 3EONA 1XFYA 4MPEA 2BU8A 3II9A
chains in the Genus database with same CATH topology
3D1IA 3OWMA 4L3YA 2FONA 2DVLA 3MPJA 4O5MA 2YYKA 3LGQA 2R0NA 4ZYJA 2OT4A 1FS9A 1IS2A 4KCFA 1RX0A 3AFFA 4Q5BA 2J7AA 3OIBA 1JQIA 3F29A 3GM6A 1FS8A 2E81A 3SCEA 4ZXVA 4NXLA 2WBIA 1W07A 3BNFA 4OO2A 5K3JA 2YYMA 3MDEA 4G5EA 1EGDA 2YYLA 2ZO5A 3OWAA 3L1TA 2IX5A 3D9DA 1UKWA 4U83A 3BNHA 2RF7A 3D9GA 3D9FA 3FCJA 3GNCA 3GQTA 3UU9A 3R7KA 2E80A 3X0YA 2IX6A 2JBSA 4M9AA 3FO3A 4IV6A 3MXLA 3SF6A 3SWOA 3BNGA 1EGCA 3EOMA 4Q1OA 3PFDA 2RDZA 2JBRA 4X28A 3MDDA 1U8VA 3AFEA 2DDHA 2PG0A 2JIFA 2YYIA 4X28C 4IRNA 3P4TA 4Q4UA 4N5FA 2D29A 3BNJA 3TTBA 4DOYA 4Q0TA 2A1TA 1SIRA 1EGEA 2UXWA 2VR0A 4L38A 4JEKA 5K3GA 3MMOA 2YYJA 4L3ZA 5K3HA 4WJYA 2YYGA 3MKHA 2ZAFA 2R0MA 3M9VA 2EBAA 2JBTA 3RKHA 3B96A 1R2JA 3X0XA 4KTOA 4XVXA 1QDBA 2REHA 1T9GA 5K3IA 2C0UA 4HR3A 4W9UA 4P13A 3HWCA 3S7WA 3D9EA 4RM7A 1GU6A 1IVHA 3SXQA 1UDYA 1SIQA 2Z1QA 4Q17A 1BUCA 3D6BA 4L3XA 4L1FA 3LG1A 2RFQA 2OR0A 4Q5CA 3TORA 2C12A 1FS7A 3NF4A 3MPIA 1OAHA 2VIGA 2CX9A 1WS9A 3EONA 3UBRA 3II9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D1I A;  3OWM A;  4L3Y A;  2FON A;  2DVL A;  3MPJ A;  4O5M A;  2YYK A;  3LGQ A;  2R0N A;  4ZYJ A;  2OT4 A;  1FS9 A;  1IS2 A;  4KCF A;  1RX0 A;  3AFF A;  4Q5B A;  2J7A A;  3OIB A;  1JQI A;  3F29 A;  3GM6 A;  1FS8 A;  2E81 A;  3SCE A;  4ZXV A;  4NXL A;  2WBI A;  1W07 A;  3BNF A;  4OO2 A;  5K3J A;  2YYM A;  3MDE A;  4G5E A;  1EGD A;  2YYL A;  2ZO5 A;  3OWA A;  3L1T A;  2IX5 A;  3D9D A;  1UKW A;  4U83 A;  3BNH A;  2RF7 A;  3D9G A;  3D9F A;  3FCJ A;  3GNC A;  3GQT A;  3UU9 A;  3R7K A;  2E80 A;  3X0Y A;  2IX6 A;  2JBS A;  4M9A A;  3FO3 A;  4IV6 A;  3MXL A;  3SF6 A;  3SWO A;  3BNG A;  1EGC A;  3EOM A;  4Q1O A;  3PFD A;  2RDZ A;  2JBR A;  4X28 A;  3MDD A;  1U8V A;  3AFE A;  2DDH A;  2PG0 A;  2JIF A;  2YYI A;  4X28 C;  4IRN A;  3P4T A;  4Q4U A;  4N5F A;  2D29 A;  3BNJ A;  3TTB A;  4DOY A;  4Q0T A;  2A1T A;  1SIR A;  1EGE A;  2UXW A;  2VR0 A;  4L38 A;  4JEK A;  5K3G A;  3MMO A;  2YYJ A;  4L3Z A;  5K3H A;  4WJY A;  2YYG A;  3MKH A;  2ZAF A;  2R0M A;  3M9V A;  2EBA A;  2JBT A;  3RKH A;  3B96 A;  1R2J A;  3X0X A;  4KTO A;  4XVX A;  1QDB A;  2REH A;  1T9G A;  5K3I A;  2C0U A;  4HR3 A;  4W9U A;  4P13 A;  3HWC A;  3S7W A;  3D9E A;  4RM7 A;  1GU6 A;  1IVH A;  3SXQ A;  1UDY A;  1SIQ A;  2Z1Q A;  4Q17 A;  1BUC A;  3D6B A;  4L3X A;  4L1F A;  3LG1 A;  2RFQ A;  2OR0 A;  4Q5C A;  3TOR A;  2C12 A;  1FS7 A;  3NF4 A;  3MPI A;  1OAH A;  2VIG A;  2CX9 A;  1WS9 A;  3EON A;  3UBR A;  3II9 A; 
#chains in the Genus database with same CATH topology
 3C2P A;  3D1I A;  3OWM A;  4H85 A;  4L3Y A;  2FON A;  2DVL A;  3MPJ A;  4O5M A;  2YYK A;  3LGQ A;  3TZ4 A;  2R0N A;  4ZYJ A;  2OT4 A;  1FS9 A;  2BU6 A;  1IS2 A;  4KCF A;  1S26 A;  1XFX A;  1RX0 A;  4FF1 A;  4KSA A;  4AKI A;  3AFF A;  4Q5B A;  4FF3 A;  2BU7 A;  4KS9 A;  4F0X A;  2J7A A;  3OIB A;  1SC5 A;  1JQI A;  3F29 A;  3GM6 A;  1FS8 A;  2E81 A;  2GBB A;  1R3B A;  3CRL A;  4LQS B;  4ZXV A;  3SCE A;  3U33 A;  3C46 A;  4NXL A;  2WBI A;  4P79 A;  1W07 A;  2CJ5 A;  2BU5 A;  3BNF A;  4OO2 A;  5J6A A;  5BRK A;  5K3J A;  2YYM A;  3MDE A;  1RP3 A;  2XS8 A;  4G5E A;  1EGD A;  2LFW A;  2YYL A;  1GKX A;  4QIC A;  2ZO5 A;  3OWA A;  2ZKJ A;  3L1T A;  2IX5 A;  3D9D A;  1UKW A;  4U83 A;  2CJ4 A;  2Q8F A;  3BNH A;  2RF7 A;  3D9G A;  3D9F A;  3FCJ A;  3GNC A;  3GQT A;  2EC5 A;  3TZ0 A;  5M4P A;  1Y0V A;  3KML A;  3UU9 A;  3Q0A A;  1K8T A;  4JIZ A;  2AZE A;  3R7K A;  2OEX A;  2E80 A;  5B5V A;  3X0Y A;  4MPN A;  2IX6 A;  2JBS A;  4M9A A;  3FO3 A;  4IV6 A;  3MXL A;  2FP2 A;  3SF6 A;  1XFZ A;  3SWO A;  2BTZ A;  2YGW A;  3VAD A;  2OEV A;  3BNG A;  1EGC A;  3EOM A;  2QR4 A;  4HKS A;  4MP7 A;  4Q1O A;  3PFD A;  1Y8O A;  2RDZ A;  3TZ2 A;  2JBR A;  2HJN A;  1JM6 A;  4X28 A;  2BU2 A;  4E00 A;  5M4M A;  3UBR A;  3MDD A;  3DJL A;  3Q23 A;  1U8V A;  3AFE A;  5M4N A;  2XS1 A;  1X90 A;  1XFV A;  1Y8N A;  1K93 A;  3CRK A;  2DDH A;  2R05 A;  2PG0 A;  2JIF A;  2YYI A;  2ZDY A;  4X28 C;  4IRN A;  2Q8H A;  3P4T A;  4Q4U A;  4N5F A;  2D29 A;  3BNJ A;  1XFW A;  4DOY A;  2R02 A;  2E0A A;  4G97 A;  4Q0T A;  2A1T A;  1XG2 B;  1X8Z A;  1SIR A;  1EGE A;  2UXW A;  2PNR A;  5GJW E;  2VR0 A;  4FF2 A;  2EBH X;  4L38 A;  4JEK A;  5K3G A;  3MMO A;  3C3L A;  2YYJ A;  4L3Z A;  5K3H A;  4KSF A;  2YYG A;  3MKH A;  4WJY A;  2EBF X;  2ZAF A;  2R0M A;  2Q8G A;  3M9V A;  4E02 A;  4H81 A;  2FP1 A;  5M4K A;  1PK0 A;  2EBA A;  2JBT A;  3RKH A;  3B96 A;  4V26 A;  3VKG A;  1R2J A;  3X0X A;  1X91 A;  4KTO A;  4FF4 A;  4XVX A;  3TTB A;  5BRM A;  1QDB A;  2REH A;  5B5W A;  1T9G A;  1GKZ A;  5K3I A;  2ZDX A;  1PI1 A;  2OJQ A;  3Q22 A;  2C0U A;  4HR3 A;  4W9U A;  1Y8P A;  5J71 A;  4P13 A;  2Q8I A;  3HWC A;  3S7W A;  4E01 A;  1SK6 A;  2CJ7 A;  3D9E A;  4RM7 A;  1GU6 A;  2AO2 A;  2CJ6 A;  4AKH A;  1IVH A;  3CE2 A;  4MPC A;  3SXQ A;  1UDY A;  5B6B A;  1XFU A;  4MP2 A;  3TZ5 A;  5GJV E;  1SIQ A;  2Z1Q A;  4Q17 A;  4AKG A;  4V25 A;  1GJV A;  1BUC A;  3D6B A;  1RJ1 A;  3X29 A;  4LQQ B;  4L3X A;  4HKR A;  3Q24 A;  4L1F A;  3LG1 A;  3VKH A;  2RFQ A;  2OR0 A;  4Q5C A;  4JIO A;  2F6L A;  2C12 A;  3TOR A;  3D2R A;  4FZ4 A;  4AI6 A;  4H7Q A;  3N0R A;  1FS7 A;  3NF4 A;  1K90 A;  4J1V A;  1RJ4 A;  2R03 A;  3MPI A;  5EZ3 A;  1OAH A;  2VIG A;  2CJ8 A;  2XQR B;  2VF1 A;  2CX9 A;  2PO4 A;  1LVC A;  4DZY A;  1WS9 A;  3EON A;  1XFY A;  4MPE A;  2BU8 A;  3II9 A; 
#chains in the Genus database with same CATH homology
 3D1I A;  3OWM A;  4L3Y A;  2FON A;  2DVL A;  3MPJ A;  4O5M A;  2YYK A;  3LGQ A;  2R0N A;  4ZYJ A;  2OT4 A;  1FS9 A;  1IS2 A;  4KCF A;  1RX0 A;  3AFF A;  4Q5B A;  2J7A A;  3OIB A;  1JQI A;  3F29 A;  3GM6 A;  1FS8 A;  2E81 A;  3SCE A;  4ZXV A;  4NXL A;  2WBI A;  1W07 A;  3BNF A;  4OO2 A;  5K3J A;  2YYM A;  3MDE A;  4G5E A;  1EGD A;  2YYL A;  2ZO5 A;  3OWA A;  3L1T A;  2IX5 A;  3D9D A;  1UKW A;  4U83 A;  3BNH A;  2RF7 A;  3D9G A;  3D9F A;  3FCJ A;  3GNC A;  3GQT A;  3UU9 A;  3R7K A;  2E80 A;  3X0Y A;  2IX6 A;  2JBS A;  4M9A A;  3FO3 A;  4IV6 A;  3MXL A;  3SF6 A;  3SWO A;  3BNG A;  1EGC A;  3EOM A;  4Q1O A;  3PFD A;  2RDZ A;  2JBR A;  4X28 A;  3MDD A;  1U8V A;  3AFE A;  2DDH A;  2PG0 A;  2JIF A;  2YYI A;  4X28 C;  4IRN A;  3P4T A;  4Q4U A;  4N5F A;  2D29 A;  3BNJ A;  3TTB A;  4DOY A;  4Q0T A;  2A1T A;  1SIR A;  1EGE A;  2UXW A;  2VR0 A;  4L38 A;  4JEK A;  5K3G A;  3MMO A;  2YYJ A;  4L3Z A;  5K3H A;  4WJY A;  2YYG A;  3MKH A;  2ZAF A;  2R0M A;  3M9V A;  2EBA A;  2JBT A;  3RKH A;  3B96 A;  1R2J A;  3X0X A;  4KTO A;  4XVX A;  1QDB A;  2REH A;  1T9G A;  5K3I A;  2C0U A;  4HR3 A;  4W9U A;  4P13 A;  3HWC A;  3S7W A;  3D9E A;  4RM7 A;  1GU6 A;  1IVH A;  3SXQ A;  1UDY A;  1SIQ A;  2Z1Q A;  4Q17 A;  1BUC A;  3D6B A;  4L3X A;  4L1F A;  3LG1 A;  2RFQ A;  2OR0 A;  4Q5C A;  3TOR A;  2C12 A;  1FS7 A;  3NF4 A;  3MPI A;  1OAH A;  2VIG A;  2CX9 A;  1WS9 A;  3EON A;  3UBR A;  3II9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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