1EC6A

Crystal structure of nova-2 kh3 k-homology rna-binding domain bound to 20-mer rna hairpin
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
87
structure length
87
Chain Sequence
MKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords 20-MER RNA HAIRPIN
total genus 27
structure length 87
sequence length 87
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 1ec6A00
2JEAI 1ZZKA 2QNDA 2CTEA 2FMRA 1X4NA 2CTKA 2P2RA 5JEAG 4AM3A 2HH3A 1WE8A 4IFDG 2CPQA 2ANRA 2E3UA 1ZZIA 3U1KA 2AXYA 2OPUA 2JE6I 1DT4A 4WANA 1KHMA 2CTLA 2Z0SA 2ANNA 2CTJA 2MJHA 2BA0A 3VKEA 4NBQA 4BA2I 4JVHA 2JZXA 2PY9A 5K36G 1WVNA 2NN6G 4AIMA 1VIHA 1ZZJA 1J4WA 4JVYA 2OPVA 4B8TA 2BL5A 4BA1I 1K1GA 2HH2A 1X4MA 2CTFA 2JA9A 2YQRA 5C0XG 2JEBI 1J5KA 1ZTGA 2DGRA 3V69A 2PQUA 1TUAA 1DTJA 4OO1G 4QMFB 4LIJA 2CTMA 3AEVB 2JVZA 1VIGA 1EC6A 3L7ZC 4WALA
chains in the Genus database with same CATH superfamily
2QNDA 5LMNH 2CTKA 4JI1H 4B3RH 1S20A 2ANRA 2UXBH 1ZZIA 4DV6H 2JE6I 4WANA 1KHMA 2CTLA 3OTOH 2ZM6H 3GKUA 2UUBH 5LMUH 1XMQH 3VKEA 1I94H 4BA2I 1N32H 4JI4H 2D9IA 1XNQH 2NN6G 5FLXW 4DV5H 1WHRA 3KDGA 1ZZJA 4JVYA 5IT9W 1J5EH 2CWFA 2LF0A 1XMOH 1IBLH 4B3MH 4EC5A 3RF2A 4NZRM 2YQRA 3FAUA 1WTJA 2DGRA 4DUZH 1HNXH 1VBIA 5BR8H 4B3SH 2HHHH 3AEVB 3L7ZC 4WALA 1FJGH 1I6UA 2FMRA 2M8WA 3OSSD 2PT7G 3UOEA 5LL6b 3J80W 1IBMH 1X0AA 5JEAG 4AM3A 4LF5H 4LFAH 2F4VH 2VQFH 3U1KA 2OPUA 1V9NA 4DUYH 3JAMW 2ANNA 4OD6A 2CTJA 2Y3MA 4NXNH 2BA0A 4LFBH 4H8AA 3T1YH 4NBQA 3T1HH 4DR4H 4X66H 2JZXA 4NZTM 2CPMA 4OX9H 1XNRH 4NXMH 2CWHA 5IWAH 2VQEH 1N34H 1VIHA 1J4WA 1NXUA 4DR7H 1ODHA 2K1HA 4FJSA 2BL5A 4YHHH 1K1GA 2M6QA 2FPHX 1X9ZA 2JEBI 3OETA 3SB1A 1DTJA 4GKJH 4QMFB 4LIJA 1VIGA 2JVZA 4X65H 2JEAI 1XRHA 2VKCA 2CTEA 4G08A 1X4NA 4JV5H 1AN7A 2O4CA 2P2RA 4JI2H 4X62H 2E5LH 2HH3A 4LF6H 4IFDG 1SEIA 2G8YA 2LRRA 4X64H 4DR1H 4LFCH 2LTMA 4JI8H 3KDKA 4OCHA 2Z0SA 4DV3H 2MJHA 2X06A 4JVHA 1S03G 4DR6H 2PY9A 2UXCH 3I0PA 2UUAH 4AIMA 3J7AK 5A2QW 2OPVA 3GR5A 1IBKH 1HNWH 4GKKH 4BA1I 4JYAH 1N33H 2CTFA 2JA9A 1N36H 4DR2H 3V69A 2PQUA 1TUAA 4LF4H 3NCVA 4LF9H 4B3TH 2LTLA 1F0XA 4DV0H 4JI7H 1ZZKA 4DV7H 1FKAH 1Z2IA 1HR0H 1V8CA 4PDBA 1WE8A 4K0KH 2CPQA 4DV4H 2E3UA 2AXYA 4AQYH 3GABA 1DT4A 3QD7X 4B8CD 2UXDH 1PQXA 3J81W 4LF8H 1MSZA 5K36G 1WVNA 1HNZH 2ZQEA 1UG8A 4JI5H 4DV1H 4E9JA 4JI0H 4LF7H 2HH2A 1X4MA 1J5KA 5C0XG 4FJUA 2A1SA 1ZTGA 2UUCH 4JI3H 3EZJA 2FFMA 4OO1G 4DR3H 4JI6H 4DV2H 4DR5H 4YY3H 2CTMA 4KHPH 5DT9A 1EC6A 4B8TA 2UU9H
chains in the Genus database with same CATH topology
2JEAI 1ZZKA 2QNDA 2CTEA 2FMRA 1X4NA 2CTKA 2P2RA 5JEAG 4AM3A 2HH3A 1WE8A 4IFDG 2CPQA 2ANRA 2E3UA 1ZZIA 3U1KA 2AXYA 2OPUA 2JE6I 1DT4A 4WANA 1KHMA 2CTLA 2Z0SA 2ANNA 2CTJA 2MJHA 2BA0A 3VKEA 4NBQA 4BA2I 4JVHA 2JZXA 2PY9A 5K36G 1WVNA 2NN6G 4AIMA 1VIHA 1ZZJA 1J4WA 4JVYA 2OPVA 4B8TA 2BL5A 4BA1I 1K1GA 2HH2A 1X4MA 2CTFA 2JA9A 2YQRA 5C0XG 2JEBI 1J5KA 1ZTGA 2DGRA 3V69A 2PQUA 1TUAA 1DTJA 4OO1G 4QMFB 4LIJA 2CTMA 3AEVB 2JVZA 1VIGA 1EC6A 3L7ZC 4WALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JEA I;  1ZZK A;  2QND A;  2CTE A;  2FMR A;  1X4N A;  2CTK A;  2P2R A;  5JEA G;  4AM3 A;  2HH3 A;  1WE8 A;  4IFD G;  2CPQ A;  2ANR A;  2E3U A;  1ZZI A;  3U1K A;  2AXY A;  2OPU A;  2JE6 I;  1DT4 A;  4WAN A;  1KHM A;  2CTL A;  2Z0S A;  2ANN A;  2CTJ A;  2MJH A;  2BA0 A;  3VKE A;  4NBQ A;  4BA2 I;  4JVH A;  2JZX A;  2PY9 A;  5K36 G;  1WVN A;  2NN6 G;  4AIM A;  1VIH A;  1ZZJ A;  1J4W A;  4JVY A;  2OPV A;  4B8T A;  2BL5 A;  4BA1 I;  1K1G A;  2HH2 A;  1X4M A;  2CTF A;  2JA9 A;  2YQR A;  5C0X G;  2JEB I;  1J5K A;  1ZTG A;  2DGR A;  3V69 A;  2PQU A;  1TUA A;  1DTJ A;  4OO1 G;  4QMF B;  4LIJ A;  2CTM A;  3AEV B;  2JVZ A;  1VIG A;  1EC6 A;  3L7Z C;  4WAL A; 
#chains in the Genus database with same CATH topology
 2QND A;  5LMN H;  2CTK A;  4JI1 H;  4B3R H;  1S20 A;  2ANR A;  2UXB H;  1ZZI A;  4DV6 H;  2JE6 I;  4WAN A;  1KHM A;  2CTL A;  3OTO H;  2ZM6 H;  3GKU A;  2UUB H;  5LMU H;  1XMQ H;  3VKE A;  1I94 H;  4BA2 I;  1N32 H;  4JI4 H;  2D9I A;  1XNQ H;  2NN6 G;  5FLX W;  4DV5 H;  1WHR A;  3KDG A;  1ZZJ A;  4JVY A;  5IT9 W;  1J5E H;  2CWF A;  2LF0 A;  1XMO H;  1IBL H;  4B3M H;  4EC5 A;  3RF2 A;  4NZR M;  2YQR A;  3FAU A;  1WTJ A;  2DGR A;  4DUZ H;  1HNX H;  1VBI A;  5BR8 H;  4B3S H;  2HHH H;  3AEV B;  3L7Z C;  4WAL A;  1FJG H;  1I6U A;  2FMR A;  2M8W A;  3OSS D;  2PT7 G;  3UOE A;  5LL6 b;  3J80 W;  1IBM H;  1X0A A;  5JEA G;  4AM3 A;  4LF5 H;  4LFA H;  2F4V H;  2VQF H;  3U1K A;  2OPU A;  1V9N A;  4DUY H;  3JAM W;  2ANN A;  4OD6 A;  2CTJ A;  2Y3M A;  4NXN H;  2BA0 A;  4LFB H;  4H8A A;  3T1Y H;  4NBQ A;  3T1H H;  4DR4 H;  4X66 H;  2JZX A;  4NZT M;  2CPM A;  4OX9 H;  1XNR H;  4NXM H;  2CWH A;  5IWA H;  2VQE H;  1N34 H;  1VIH A;  1J4W A;  1NXU A;  4DR7 H;  1ODH A;  2K1H A;  4FJS A;  2BL5 A;  4YHH H;  1K1G A;  2M6Q A;  2FPH X;  1X9Z A;  2JEB I;  3OET A;  3SB1 A;  1DTJ A;  4GKJ H;  4QMF B;  4LIJ A;  1VIG A;  2JVZ A;  4X65 H;  2JEA I;  1XRH A;  2VKC A;  2CTE A;  4G08 A;  1X4N A;  4JV5 H;  1AN7 A;  2O4C A;  2P2R A;  4JI2 H;  4X62 H;  2E5L H;  2HH3 A;  4LF6 H;  4IFD G;  1SEI A;  2G8Y A;  2LRR A;  4X64 H;  4DR1 H;  4LFC H;  2LTM A;  4JI8 H;  3KDK A;  4OCH A;  2Z0S A;  4DV3 H;  2MJH A;  2X06 A;  4JVH A;  1S03 G;  4DR6 H;  2PY9 A;  2UXC H;  3I0P A;  2UUA H;  4AIM A;  3J7A K;  5A2Q W;  2OPV A;  3GR5 A;  1IBK H;  1HNW H;  4GKK H;  4BA1 I;  4JYA H;  1N33 H;  2CTF A;  2JA9 A;  1N36 H;  4DR2 H;  3V69 A;  2PQU A;  1TUA A;  4LF4 H;  3NCV A;  4LF9 H;  4B3T H;  2LTL A;  1F0X A;  4DV0 H;  4JI7 H;  1ZZK A;  4DV7 H;  1FKA H;  1Z2I A;  1HR0 H;  1V8C A;  4PDB A;  1WE8 A;  4K0K H;  2CPQ A;  4DV4 H;  2E3U A;  2AXY A;  4AQY H;  3GAB A;  1DT4 A;  3QD7 X;  4B8C D;  2UXD H;  1PQX A;  3J81 W;  4LF8 H;  1MSZ A;  5K36 G;  1WVN A;  1HNZ H;  2ZQE A;  1UG8 A;  4JI5 H;  4DV1 H;  4E9J A;  4JI0 H;  4LF7 H;  2HH2 A;  1X4M A;  1J5K A;  5C0X G;  4FJU A;  2A1S A;  1ZTG A;  2UUC H;  4JI3 H;  3EZJ A;  2FFM A;  4OO1 G;  4DR3 H;  4JI6 H;  4DV2 H;  4DR5 H;  4YY3 H;  2CTM A;  4KHP H;  5DT9 A;  1EC6 A;  4B8T A;  2UU9 H; 
#chains in the Genus database with same CATH homology
 2JEA I;  1ZZK A;  2QND A;  2CTE A;  2FMR A;  1X4N A;  2CTK A;  2P2R A;  5JEA G;  4AM3 A;  2HH3 A;  1WE8 A;  4IFD G;  2CPQ A;  2ANR A;  2E3U A;  1ZZI A;  3U1K A;  2AXY A;  2OPU A;  2JE6 I;  1DT4 A;  4WAN A;  1KHM A;  2CTL A;  2Z0S A;  2ANN A;  2CTJ A;  2MJH A;  2BA0 A;  3VKE A;  4NBQ A;  4BA2 I;  4JVH A;  2JZX A;  2PY9 A;  5K36 G;  1WVN A;  2NN6 G;  4AIM A;  1VIH A;  1ZZJ A;  1J4W A;  4JVY A;  2OPV A;  4B8T A;  2BL5 A;  4BA1 I;  1K1G A;  2HH2 A;  1X4M A;  2CTF A;  2JA9 A;  2YQR A;  5C0X G;  2JEB I;  1J5K A;  1ZTG A;  2DGR A;  3V69 A;  2PQU A;  1TUA A;  1DTJ A;  4OO1 G;  4QMF B;  4LIJ A;  2CTM A;  3AEV B;  2JVZ A;  1VIG A;  1EC6 A;  3L7Z C;  4WAL A; 
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similar chains in the pdb database (?% sequence similarity)

 
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