2LRRA

Solution structure of the r3h domain from human smubp-2 in complex with 2'-deoxyguanosine-5'-monophosphate
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
70
structure length
70
Chain Sequence
PEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for 5'-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Smubp-2
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DNA-binding protein SMUBP-2
total genus 20
structure length 70
sequence length 70
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2012-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01424 R3H R3H domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.50 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 R3H-like domain 2lrrA00
1MSZA 2LRRA 1WHRA 1UG8A 3GKUA 2A1SA 2CPMA
chains in the Genus database with same CATH superfamily
4X62H 2HH3A 2UUBH 4JYAH 1WE8A 1FJGH 1V9NA 4DV6H 3JAMW 2QNDA 2O4CA 1XNQH 4WANA 2CTEA 2FPHX 4H8AA 4AQYH 2UU9H 4B3RH 5A2QW 1XRHA 2Y3MA 1X9ZA 4JVYA 2UXDH 1N33H 2G8YA 2VKCA 2BL5A 4LIJA 1Z2IA 4JI5H 4DR2H 2E3UA 2VQFH 2JEAI 1UG8A 3L7ZC 4NZTM 5K36G 4YY3H 1ODHA 4GKJH 4JVHA 1HNWH 4GKKH 1ZZJA 4DR7H 4JI8H 2PY9A 2CTKA 2A1SA 1DT4A 1EC6A 4EC5A 4OX9H 5BR8H 1VIHA 4X65H 1HNXH 1DTJA 4DV4H 4OO1G 4DR4H 3GABA 3EZJA 5JEAG 4AIMA 2ANRA 4FJSA 4DV2H 3J7AK 4B8CD 1MSZA 4LF6H 3UOEA 4AM3A 2Z0SA 3T1YH 2CWFA 4B8TA 2LTLA 2UUAH 4LF8H 1XMOH 1J5EH 4DV7H 1SEIA 1IBMH 4LF9H 2CWHA 2DGRA 4FJUA 5LL6b 2HH2A 2LF0A 5LMNH 2ZM6H 1N36H 4B3SH 4JI3H 1X4NA 2ANNA 4JI2H 2YQRA 2VQEH 1WHRA 4KHPH 1J4WA 4NBQA 1F0XA 2PT7G 1AN7A 3I0PA 2K1HA 5FLXW 2FMRA 1J5KA 4JI7H 1N32H 1WTJA 2UXBH 3NCVA 4QMFB 1XMQH 2CPMA 2BA0A 1S03G 1VBIA 3GR5A 1ZZKA 3V69A 4B3MH 4X64H 4DV0H 3GKUA 2OPVA 2P2RA 5C0XG 1WVNA 2FFMA 3U1KA 4NXNH 4DV3H 4DR6H 1X4MA 4DUZH 4LFAH 2JEBI 4DR1H 4DR5H 3VKEA 4LF4H 1XNRH 3J80W 2X06A 4WALA 1IBLH 1PQXA 1IBKH 3SB1A 4DV1H 4JV5H 5IT9W 1FKAH 4B3TH 1TUAA 2ZQEA 4OD6A 4X66H 4NXMH 1I94H 4JI0H 4IFDG 2D9IA 4LF7H 2NN6G 1NXUA 4E9JA 4PDBA 3FAUA 4DR3H 1N34H 1HR0H 2PQUA 3J81W 2AXYA 1X0AA 4G08A 4JI6H 3KDGA 2JA9A 4DV5H 3OTOH 2M8WA 2UXCH 2CTJA 4BA1I 4JI1H 1S20A 2CPQA 2JE6I 2LTMA 4LF5H 3AEVB 3OETA 4DUYH 1ZTGA 4LFBH 2CTLA 3QD7X 5IWAH 2E5LH 2JVZA 1V8CA 2CTMA 5DT9A 2MJHA 3OSSD 4BA2I 4OCHA 3RF2A 2HHHH 2UUCH 2F4VH 1HNZH 4K0KH 1I6UA 1KHMA 2M6QA 3T1HH 2LRRA 3KDKA 4YHHH 1K1GA 4LFCH 2JZXA 1ZZIA 5LMUH 4JI4H 2CTFA 2OPUA 4NZRM 1VIGA
chains in the Genus database with same CATH topology
1MSZA 2LRRA 1WHRA 1UG8A 3GKUA 2A1SA 2CPMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MSZ A;  2LRR A;  1WHR A;  1UG8 A;  3GKU A;  2A1S A;  2CPM A; 
#chains in the Genus database with same CATH topology
 4X62 H;  2HH3 A;  2UUB H;  4JYA H;  1WE8 A;  1FJG H;  1V9N A;  4DV6 H;  3JAM W;  2QND A;  2O4C A;  1XNQ H;  4WAN A;  2CTE A;  2FPH X;  4H8A A;  4AQY H;  2UU9 H;  4B3R H;  5A2Q W;  1XRH A;  2Y3M A;  1X9Z A;  4JVY A;  2UXD H;  1N33 H;  2G8Y A;  2VKC A;  2BL5 A;  4LIJ A;  1Z2I A;  4JI5 H;  4DR2 H;  2E3U A;  2VQF H;  2JEA I;  1UG8 A;  3L7Z C;  4NZT M;  5K36 G;  4YY3 H;  1ODH A;  4GKJ H;  4JVH A;  1HNW H;  4GKK H;  1ZZJ A;  4DR7 H;  4JI8 H;  2PY9 A;  2CTK A;  2A1S A;  1DT4 A;  1EC6 A;  4EC5 A;  4OX9 H;  5BR8 H;  1VIH A;  4X65 H;  1HNX H;  1DTJ A;  4DV4 H;  4OO1 G;  4DR4 H;  3GAB A;  3EZJ A;  5JEA G;  4AIM A;  2ANR A;  4FJS A;  4DV2 H;  3J7A K;  4B8C D;  1MSZ A;  4LF6 H;  3UOE A;  4AM3 A;  2Z0S A;  3T1Y H;  2CWF A;  4B8T A;  2LTL A;  2UUA H;  4LF8 H;  1XMO H;  1J5E H;  4DV7 H;  1SEI A;  1IBM H;  4LF9 H;  2CWH A;  2DGR A;  4FJU A;  5LL6 b;  2HH2 A;  2LF0 A;  5LMN H;  2ZM6 H;  1N36 H;  4B3S H;  4JI3 H;  1X4N A;  2ANN A;  4JI2 H;  2YQR A;  2VQE H;  1WHR A;  4KHP H;  1J4W A;  4NBQ A;  1F0X A;  2PT7 G;  1AN7 A;  3I0P A;  2K1H A;  5FLX W;  2FMR A;  1J5K A;  4JI7 H;  1N32 H;  1WTJ A;  2UXB H;  3NCV A;  4QMF B;  1XMQ H;  2CPM A;  2BA0 A;  1S03 G;  1VBI A;  3GR5 A;  1ZZK A;  3V69 A;  4B3M H;  4X64 H;  4DV0 H;  3GKU A;  2OPV A;  2P2R A;  5C0X G;  1WVN A;  2FFM A;  3U1K A;  4NXN H;  4DV3 H;  4DR6 H;  1X4M A;  4DUZ H;  4LFA H;  2JEB I;  4DR1 H;  4DR5 H;  3VKE A;  4LF4 H;  1XNR H;  3J80 W;  2X06 A;  4WAL A;  1IBL H;  1PQX A;  1IBK H;  3SB1 A;  4DV1 H;  4JV5 H;  5IT9 W;  1FKA H;  4B3T H;  1TUA A;  2ZQE A;  4OD6 A;  4X66 H;  4NXM H;  1I94 H;  4JI0 H;  4IFD G;  2D9I A;  4LF7 H;  2NN6 G;  1NXU A;  4E9J A;  4PDB A;  3FAU A;  4DR3 H;  1N34 H;  1HR0 H;  2PQU A;  3J81 W;  2AXY A;  1X0A A;  4G08 A;  4JI6 H;  3KDG A;  2JA9 A;  4DV5 H;  3OTO H;  2M8W A;  2UXC H;  2CTJ A;  4BA1 I;  4JI1 H;  1S20 A;  2CPQ A;  2JE6 I;  2LTM A;  4LF5 H;  3AEV B;  3OET A;  4DUY H;  1ZTG A;  4LFB H;  2CTL A;  3QD7 X;  5IWA H;  2E5L H;  2JVZ A;  1V8C A;  2CTM A;  5DT9 A;  2MJH A;  3OSS D;  4BA2 I;  4OCH A;  3RF2 A;  2HHH H;  2UUC H;  2F4V H;  1HNZ H;  4K0K H;  1I6U A;  1KHM A;  2M6Q A;  3T1H H;  2LRR A;  3KDK A;  4YHH H;  1K1G A;  4LFC H;  2JZX A;  1ZZI A;  5LMU H;  4JI4 H;  2CTF A;  2OPU A;  4NZR M;  1VIG A; 
#chains in the Genus database with same CATH homology
 1MSZ A;  2LRR A;  1WHR A;  1UG8 A;  3GKU A;  2A1S A;  2CPM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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