1NXUA

Crystal structure of e. coli hypothetical oxidoreductase yiak northeast structural genomics consortium target er82.
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
332
structure length
332
Chain Sequence
MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
pubmed doi rcsb
molecule tags Structural genomics, oxidoreductase
source organism Escherichia coli
molecule keywords Hypothetical oxidoreductase yiaK
total genus 96
structure length 332
sequence length 332
chains with identical sequence B
ec nomenclature ec 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase.
pdb deposition date 2003-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1nxuA01
3.30.60.50 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Hypothetical oxidoreductase yiak; domain 3 1nxuA03
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1nxuA02
2X06A 4FJUA 4H8AA 3UOEA 1S20A 1V9NA 1VBIA 2CWFA 1NXUA 2CWHA 1WTJA 1XRHA 1Z2IA 3I0PA 4FJSA 1X0AA 2G8YA
chains in the Genus database with same CATH superfamily
1LR7A 2JYYA 1SGYI 4X65H 4JYAH 4A24A 2ZQEA 5E3QA 1K7UA 5DT9A 4DV4H 1TBQR 4AMLA 3FSYA 4B3TH 2WVJA 2LRRA 3UOEA 2ORVA 1DS2I 3TOAA 1SGRI 2M6QA 2LB7A 1CT4I 4JI7H 1PCEA 4GKJH 5EX0A 1HR0H 1UG8A 5JEAG 1YU6C 3PDNA 1K7TA 1HNXH 1K1GA 1CT2I 3UGLA 1IY6A 1SGQI 1HJAI 1U5KA 2K9HA 1OMUA 2F3CI 1N13A 2ORWA 4PDBA 2PT7G 2CTFA 2X06A 1HNZH 2UXBH 1WVNA 2PQ8A 2CTEA 2WGCA 1X9ZA 4OVOA 2N71A 3R5DA 1XX6A 3J7AK 4BA2I 1I6UA 2OZUA 3R5CA 2ELIA 2XRCA 3R5AA 4AIMA 4FJSA 3SGBI 1Z7KB 2VRWB 3TO9A 2FFMA 5HI7A 1X0AA 1AN1I 3KDGA 1EC6A 1HDLA 1TIHA 2OU2A 4UXIA 2HH2A 5FLXW 4DV1H 4IFDG 2ARPF 1CGII 3E2IA 1FY7A 2DIPA 3VDPA 1CGJI 2P2RA 3QD7X 2QQCA 1M8CA 4NXMH 1NXUA 2LTMA 2M5XA 4NBQA 5J8CA 1MJ9A 2DKVA 5A2QW 2LUYA 4DV6H 2B8TA 2SGQI 4JVHA 3I0PA 4AQYH 1ZTGA 5C0XG 3SGQI 2F4VH 2JW6A 3CXLA 2E5RA 5E3PA 1SGEI 2YUUA 2JEAI 4WANA 3VDUA 1WE8A 2X52A 1P9ZA 3U1KA 1F0XA 1V1HA 1FJGH 1WTJA 2LTLA 5FUVA 1V8CA 2LEOA 2B0UC 4H8AA 4JI5H 4DR1H 4GKKH 2N1AB 1KBEA 1TBOA 5FUYA 1KHMA 4K0KH 4DR4H 2QPOA 1DTJA 3TJQA 4MPIA 3V69A 1R0RI 2KMRA 1M8BA 1R79A 1IBMH 3FSXA 2KMPA 2QNDA 1LR8A 1SGPI 3SB1A 4B3SH 1OVOA 2JVZA 4DV2H 1V9NA 2SGFI 3J80W 1IW4A 1ULMA 5IT9W 2ROWA 3RF2A 1PQXA 4B8CD 2Z0SA 2WCYA 2HHHH 2JA1A 4G08A 1P9GA 4QMFB 2UUCH 4LFBH 1UVFA 2NU3I 1TGSI 2E3UA 4EC5A 2SGPI 2NU0I 2A1SA 2KMQA 1V1IA 3OVOA 4LF6H 4GI3C 5FUWA 4WALA 1XMOH 1HEVA 3AEVB 1SGNI 4OX9H 2QQ0A 2JZMA 3QAHA 2BL5A 3UGIA 3QTLD 2YQPA 1XBTA 3J81W 3GOXA 4DR7H 1TUSA 3NCVA 2MJHA 2CWFA 2AXYA 4DR6H 4NZRM 4E1PA 1N32H 3GABA 2KCXA 2OVOA 1ZZIA 1H0ZA 2VKCA 2VQEH 2NU1I 1CHOI 1WGTA 4DR3H 1FAQA 3OSSD 2QQDA 4LFAH 2G8YA 3JAMW 4BA1I 4E1RA 2OPUA 2FPHX 2NU4I 3GR5A 4B3MH 2CWGA 4DV7H 1VDDA 2UXDH 1PPFI 1TUAA 3EZJA 4DUYH 2ANRA 2PQUA 2QQEA 4FJUA 2DB6A 2YQRA 4DV5H 1X4NA 2GVIA 1S20A 2M8WA 1UUCA 1UVGA 1PJUA 2KMOA 3FC3A 4LF5H 1XA6A 5DAEA 1Y1CA 1WGCA 4JI2H 4LFCH 4LF7H 1YTPA 2LF0A 1K7VA 4DR2H 7WGAA 1MJAA 1BUSA 3D00A 3RU0A 2JZXA 1X4SA 1ODHA 3QWPA 2RIJA 4YHHH 3OXLA 1CE3A 2ODDA 4OO1G 1NUBA 2K1HA 2NU2I 1AN7A 5EX3A 2SGDI 1TOTA 3UEJA 1X74A 2UU9H 1XMQH 4HGUA 4JI4H 1Z2IA 2X3TA 1VIHA 2O4CA 4DNCA 1KBFA 1J5EH 1XNRH 5HQ8A 1UHAA 1W4RA 3BJIA 1KMAA 2UZ3A 2CTMA 3T1YH 1DS3I 5LL6b 3OL0A 1ULNA 3TO6A 2SGEI 4DV3H 3UEYA 3R5BA 4JI8H 4AM3A 1S03G 2CJSC 2V1CC 2ANNA 2UVOA 1TBRR 2J9RA 4OD6A 2HH3A 5FUXA 1W3SA 4WP4A 4DV0H 3TO7A 1ZZJA 1PTRA 3MEKA 2N17A 1VBIA 4JCVE 5IWAH 2P6AC 1ZZKA 3KY9A 2GKRI 2NN6G 4OCHA 3UFFA 4E9JA 1XNQH 2UXCH 3UGDA 3TOBA 1MSZA 2ENZA 2GKTI 4DR5H 2V53A 2CTJA 4UXHA 2RC4A 2CWHA 5E3RA 1CSOI 1Y8FA 1MJBA 1N36H 2CPQA 4FKDA 4LF8H 1TBNA 1MT1A 2UUBH 1OMTA 3FAUA 2E5LH 4LF9H 5LMUH 2OPVA 1TURA 1XRHA 2JXDA 2JA9A 5LMNH 3VKEA 2CTKA 3SEKC 2ENNA 1N34H 1FARA 4DUZH 2D9IA 5CCMA 2W0TA 1RFHA 4JI6H 1WHRA 4YY3H 2VQFH 1BMOA 2OD1A 4B3RH 1DT4A 4JI1H 2N52A 2ERWA 1J4WA 2ZM6H 4B6DA 5K36G 4LF4H 4JV5H 3B4VC 4B8TA 2L8EA 3OTOH 3OXGA 4X64H 4L9MA 1ULKA 1CT0I 4UXJA 4NZTM 4NXNH 3E59A 2J87A 2DGRA 1HPTA 2JE6I 2E73A 4LIJA 4JI3H 4JVYA 1LR9A 1PTQA 3KDKA 3OXFA 2Y3MA 5BR8H 2GKVA 1Q9BA 9WGAA 1HNWH 3OETA 1Y1BA 2Y0MA 4KHPH 5CCLA 4SGBI 5JHWC 1OYVI 2CTLA 2A20A 2PY9A 2BUSA 1IBKH 2FNFX 1VIGA 2JEBI 1N33H 4X66H 1FYBA 1I94H 2BA0A 1SGDI 2V1CA 3HH2C 1IY5A 2UUAH 2CPMA 3L7ZC 2FMRA 1SEIA 4JI0H 2GIVA 1WKXA 1X4MA 1FKAH 1IBLH 3T1HH 1J5KA 2L7XA 4X62H 5J8FA 3GKUA 3VE5A
chains in the Genus database with same CATH topology
2X06A 4FJUA 4H8AA 3UOEA 1S20A 1V9NA 1VBIA 2CWFA 1NXUA 2CWHA 1WTJA 1XRHA 1Z2IA 3I0PA 4FJSA 1X0AA 2G8YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X06 A;  4FJU A;  4H8A A;  3UOE A;  1S20 A;  1V9N A;  1VBI A;  2CWF A;  1NXU A;  2CWH A;  1WTJ A;  1XRH A;  1Z2I A;  3I0P A;  4FJS A;  1X0A A;  2G8Y A; 
#chains in the Genus database with same CATH topology
 1LR7 A;  2JYY A;  1SGY I;  4X65 H;  4JYA H;  4A24 A;  2ZQE A;  5E3Q A;  1K7U A;  5DT9 A;  4DV4 H;  1TBQ R;  4AML A;  3FSY A;  4B3T H;  2WVJ A;  2LRR A;  3UOE A;  2ORV A;  1DS2 I;  3TOA A;  1SGR I;  2M6Q A;  2LB7 A;  1CT4 I;  4JI7 H;  1PCE A;  4GKJ H;  5EX0 A;  1HR0 H;  1UG8 A;  5JEA G;  1YU6 C;  3PDN A;  1K7T A;  1HNX H;  1K1G A;  1CT2 I;  3UGL A;  1IY6 A;  1SGQ I;  1HJA I;  1U5K A;  2K9H A;  1OMU A;  2F3C I;  1N13 A;  2ORW A;  4PDB A;  2PT7 G;  2CTF A;  2X06 A;  1HNZ H;  2UXB H;  1WVN A;  2PQ8 A;  2CTE A;  2WGC A;  1X9Z A;  4OVO A;  2N71 A;  3R5D A;  1XX6 A;  3J7A K;  4BA2 I;  1I6U A;  2OZU A;  3R5C A;  2ELI A;  2XRC A;  3R5A A;  4AIM A;  4FJS A;  3SGB I;  1Z7K B;  2VRW B;  3TO9 A;  2FFM A;  5HI7 A;  1X0A A;  1AN1 I;  3KDG A;  1EC6 A;  1HDL A;  1TIH A;  2OU2 A;  4UXI A;  2HH2 A;  5FLX W;  4DV1 H;  4IFD G;  2ARP F;  1CGI I;  3E2I A;  1FY7 A;  2DIP A;  3VDP A;  1CGJ I;  2P2R A;  3QD7 X;  2QQC A;  1M8C A;  4NXM H;  1NXU A;  2LTM A;  2M5X A;  4NBQ A;  5J8C A;  1MJ9 A;  2DKV A;  5A2Q W;  2LUY A;  4DV6 H;  2B8T A;  2SGQ I;  4JVH A;  3I0P A;  4AQY H;  1ZTG A;  5C0X G;  3SGQ I;  2F4V H;  2JW6 A;  3CXL A;  2E5R A;  5E3P A;  1SGE I;  2YUU A;  2JEA I;  4WAN A;  3VDU A;  1WE8 A;  2X52 A;  1P9Z A;  3U1K A;  1F0X A;  1V1H A;  1FJG H;  1WTJ A;  2LTL A;  5FUV A;  1V8C A;  2LEO A;  2B0U C;  4H8A A;  4JI5 H;  4DR1 H;  4GKK H;  2N1A B;  1KBE A;  1TBO A;  5FUY A;  1KHM A;  4K0K H;  4DR4 H;  2QPO A;  1DTJ A;  3TJQ A;  4MPI A;  3V69 A;  1R0R I;  2KMR A;  1M8B A;  1R79 A;  1IBM H;  3FSX A;  2KMP A;  2QND A;  1LR8 A;  1SGP I;  3SB1 A;  4B3S H;  1OVO A;  2JVZ A;  4DV2 H;  1V9N A;  2SGF I;  3J80 W;  1IW4 A;  1ULM A;  5IT9 W;  2ROW A;  3RF2 A;  1PQX A;  4B8C D;  2Z0S A;  2WCY A;  2HHH H;  2JA1 A;  4G08 A;  1P9G A;  4QMF B;  2UUC H;  4LFB H;  1UVF A;  2NU3 I;  1TGS I;  2E3U A;  4EC5 A;  2SGP I;  2NU0 I;  2A1S A;  2KMQ A;  1V1I A;  3OVO A;  4LF6 H;  4GI3 C;  5FUW A;  4WAL A;  1XMO H;  1HEV A;  3AEV B;  1SGN I;  4OX9 H;  2QQ0 A;  2JZM A;  3QAH A;  2BL5 A;  3UGI A;  3QTL D;  2YQP A;  1XBT A;  3J81 W;  3GOX A;  4DR7 H;  1TUS A;  3NCV A;  2MJH A;  2CWF A;  2AXY A;  4DR6 H;  4NZR M;  4E1P A;  1N32 H;  3GAB A;  2KCX A;  2OVO A;  1ZZI A;  1H0Z A;  2VKC A;  2VQE H;  2NU1 I;  1CHO I;  1WGT A;  4DR3 H;  1FAQ A;  3OSS D;  2QQD A;  4LFA H;  2G8Y A;  3JAM W;  4BA1 I;  4E1R A;  2OPU A;  2FPH X;  2NU4 I;  3GR5 A;  4B3M H;  2CWG A;  4DV7 H;  1VDD A;  2UXD H;  1PPF I;  1TUA A;  3EZJ A;  4DUY H;  2ANR A;  2PQU A;  2QQE A;  4FJU A;  2DB6 A;  2YQR A;  4DV5 H;  1X4N A;  2GVI A;  1S20 A;  2M8W A;  1UUC A;  1UVG A;  1PJU A;  2KMO A;  3FC3 A;  4LF5 H;  1XA6 A;  5DAE A;  1Y1C A;  1WGC A;  4JI2 H;  4LFC H;  4LF7 H;  1YTP A;  2LF0 A;  1K7V A;  4DR2 H;  7WGA A;  1MJA A;  1BUS A;  3D00 A;  3RU0 A;  2JZX A;  1X4S A;  1ODH A;  3QWP A;  2RIJ A;  4YHH H;  3OXL A;  1CE3 A;  2ODD A;  4OO1 G;  1NUB A;  2K1H A;  2NU2 I;  1AN7 A;  5EX3 A;  2SGD I;  1TOT A;  3UEJ A;  1X74 A;  2UU9 H;  1XMQ H;  4HGU A;  4JI4 H;  1Z2I A;  2X3T A;  1VIH A;  2O4C A;  4DNC A;  1KBF A;  1J5E H;  1XNR H;  5HQ8 A;  1UHA A;  1W4R A;  3BJI A;  1KMA A;  2UZ3 A;  2CTM A;  3T1Y H;  1DS3 I;  5LL6 b;  3OL0 A;  1ULN A;  3TO6 A;  2SGE I;  4DV3 H;  3UEY A;  3R5B A;  4JI8 H;  4AM3 A;  1S03 G;  2CJS C;  2V1C C;  2ANN A;  2UVO A;  1TBR R;  2J9R A;  4OD6 A;  2HH3 A;  5FUX A;  1W3S A;  4WP4 A;  4DV0 H;  3TO7 A;  1ZZJ A;  1PTR A;  3MEK A;  2N17 A;  1VBI A;  4JCV E;  5IWA H;  2P6A C;  1ZZK A;  3KY9 A;  2GKR I;  2NN6 G;  4OCH A;  3UFF A;  4E9J A;  1XNQ H;  2UXC H;  3UGD A;  3TOB A;  1MSZ A;  2ENZ A;  2GKT I;  4DR5 H;  2V53 A;  2CTJ A;  4UXH A;  2RC4 A;  2CWH A;  5E3R A;  1CSO I;  1Y8F A;  1MJB A;  1N36 H;  2CPQ A;  4FKD A;  4LF8 H;  1TBN A;  1MT1 A;  2UUB H;  1OMT A;  3FAU A;  2E5L H;  4LF9 H;  5LMU H;  2OPV A;  1TUR A;  1XRH A;  2JXD A;  2JA9 A;  5LMN H;  3VKE A;  2CTK A;  3SEK C;  2ENN A;  1N34 H;  1FAR A;  4DUZ H;  2D9I A;  5CCM A;  2W0T A;  1RFH A;  4JI6 H;  1WHR A;  4YY3 H;  2VQF H;  1BMO A;  2OD1 A;  4B3R H;  1DT4 A;  4JI1 H;  2N52 A;  2ERW A;  1J4W A;  2ZM6 H;  4B6D A;  5K36 G;  4LF4 H;  4JV5 H;  3B4V C;  4B8T A;  2L8E A;  3OTO H;  3OXG A;  4X64 H;  4L9M A;  1ULK A;  1CT0 I;  4UXJ A;  4NZT M;  4NXN H;  3E59 A;  2J87 A;  2DGR A;  1HPT A;  2JE6 I;  2E73 A;  4LIJ A;  4JI3 H;  4JVY A;  1LR9 A;  1PTQ A;  3KDK A;  3OXF A;  2Y3M A;  5BR8 H;  2GKV A;  1Q9B A;  9WGA A;  1HNW H;  3OET A;  1Y1B A;  2Y0M A;  4KHP H;  5CCL A;  4SGB I;  5JHW C;  1OYV I;  2CTL A;  2A20 A;  2PY9 A;  2BUS A;  1IBK H;  2FNF X;  1VIG A;  2JEB I;  1N33 H;  4X66 H;  1FYB A;  1I94 H;  2BA0 A;  1SGD I;  2V1C A;  3HH2 C;  1IY5 A;  2UUA H;  2CPM A;  3L7Z C;  2FMR A;  1SEI A;  4JI0 H;  2GIV A;  1WKX A;  1X4M A;  1FKA H;  1IBL H;  3T1H H;  1J5K A;  2L7X A;  4X62 H;  5J8F A;  3GKU A;  3VE5 A; 
#chains in the Genus database with same CATH homology
 2X06 A;  4FJU A;  4H8A A;  3UOE A;  1S20 A;  1V9N A;  1VBI A;  2CWF A;  1NXU A;  2CWH A;  1WTJ A;  1XRH A;  1Z2I A;  3I0P A;  4FJS A;  1X0A A;  2G8Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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