2ANNA

Crystal structure (i) of nova-1 kh1/kh2 domain tandem with 25 nt rna hairpin
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
175
structure length
148
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQNRVVTVSGEPEQNRKAVELIIQKIQEDP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*
publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Rna-binding protein/rna
total genus 41
structure length 148
sequence length 175
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA02
3V69A 1WVNA 2CPQA 2HH2A 3VKEA 2BA0A 2P2RA 2ANRA 2ANNA 2JEBI 4OO1G 1ZZKA 2JVZA 2Z0SA 2HH3A 2CTFA 1J5KA 1X4NA 4IFDG 2CTKA 4BA2I 2QNDA 4WALA 3U1KA 4B8TA 1X4MA 1ZZJA 2PY9A 1VIHA 1DT4A 1ZZIA 2E3UA 1TUAA 2AXYA 4NBQA 1J4WA 1K1GA 2PQUA 2CTEA 4JVHA 2MJHA 2FMRA 2NN6G 1DTJA 2BL5A 2CTJA 2CTMA 2OPVA 2YQRA 1VIGA 5C0XG 4JVYA 2JA9A 2JE6I 3L7ZC 1WE8A 3AEVB 4AM3A 2JEAI 4WANA 4QMFB 4AIMA 5K36G 4LIJA 2CTLA 1EC6A 2DGRA 1KHMA 4BA1I 2JZXA 1ZTGA 5JEAG 2OPUA
chains in the Genus database with same CATH superfamily
4DV7H 2HH2A 3VKEA 4JV5H 4LF5H 4DV1H 2ANRA 4JI4H 2JEBI 4OO1G 1S20A 4G08A 2VKCA 2UXDH 1X9ZA 1I6UA 1VIHA 3I0PA 4B8CD 4X65H 4NXMH 4B3RH 2LRRA 1Z2IA 2M8WA 3GKUA 4X62H 2CWFA 3OSSD 2PQUA 2O4CA 4DR2H 2FMRA 4OCHA 1SEIA 2UXCH 5C0XG 2OPVA 4JI7H 4JI8H 1VIGA 4GKKH 4JVYA 2JA9A 4JI3H 1ODHA 2UUAH 1IBLH 4EC5A 4AM3A 4DUYH 4WANA 1FJGH 3KDKA 4LIJA 1N36H 2CPMA 2JZXA 1KHMA 2OPUA 3V69A 4DR5H 4LF6H 2JEAI 1WVNA 2CPQA 2P2RA 4JI2H 3UOEA 2LF0A 2VQFH 1ZZKA 1J5KA 1AN7A 2ZQEA 2K1HA 4DR3H 2QNDA 3U1KA 4B8TA 5IT9W 2D9IA 1ZZJA 1DT4A 1ZZIA 4JI5H 3KDGA 2AXYA 4JYAH 1J4WA 1K1GA 5LMNH 4JVHA 4LFAH 2PT7G 2MJHA 4FJUA 3RF2A 4DV5H 4NZTM 4DV0H 4X64H 3J81W 2CTJA 2CTMA 2YQRA 1WTJA 3EZJA 4DV4H 5FLXW 3AEVB 1PQXA 4AQYH 1XNQH 1V9NA 4AIMA 2FFMA 5LMUH 5K36G 1IBMH 2CTLA 4X66H 4OX9H 4IFDG 4YHHH 4DV3H 1F0XA 4OD6A 3OETA 2JVZA 2Z0SA 3FAUA 5IWAH 2CTFA 3QD7X 4DR6H 5BR8H 4GKJH 2CTKA 2FPHX 4BA2I 2M6QA 4WALA 3SB1A 2PY9A 1HNWH 4K0KH 3J7AK 2LTLA 1NXUA 4NZRM 1XMQH 4JI1H 2F4VH 4H8AA 1HNXH 1XRHA 2UUBH 4LFBH 2BL5A 2HHHH 4DR4H 3L7ZC 2JE6I 2UXBH 2A1SA 1X0AA 4QMFB 1FKAH 1N34H 3GR5A 2DGRA 3JAMW 5LL6b 4B3SH 4PDBA 2G8YA 4DV6H 2UUCH 4LF9H 1VBIA 1XMOH 3GABA 2CWHA 5A2QW 2BA0A 4DR1H 1I94H 4JI0H 4JI6H 1N32H 4DR7H 2ANNA 4E9JA 2LTMA 3J80W 4DV2H 4NXNH 2HH3A 1X4NA 4YY3H 4LFCH 1WHRA 4FJSA 1X4MA 3T1HH 4DUZH 2E3UA 1TUAA 3NCVA 4NBQA 2VQEH 1HNZH 1J5EH 2UU9H 1UG8A 2Y3MA 2CTEA 1IBKH 2ZM6H 2NN6G 1DTJA 4LF7H 5DT9A 3T1YH 1N33H 1WE8A 2E5LH 1MSZA 4LF4H 1HR0H 4B3TH 3OTOH 1S03G 1EC6A 4KHPH 1XNRH 4LF8H 2X06A 4BA1I 4B3MH 1ZTGA 5JEAG 1V8CA
chains in the Genus database with same CATH topology
3V69A 1WVNA 2CPQA 2HH2A 3VKEA 2BA0A 2P2RA 2ANRA 2ANNA 2JEBI 4OO1G 1ZZKA 2JVZA 2Z0SA 2HH3A 2CTFA 1J5KA 1X4NA 4IFDG 2CTKA 4BA2I 2QNDA 4WALA 3U1KA 4B8TA 1X4MA 1ZZJA 2PY9A 1VIHA 1DT4A 1ZZIA 2E3UA 1TUAA 2AXYA 4NBQA 1J4WA 1K1GA 2PQUA 2CTEA 4JVHA 2MJHA 2FMRA 2NN6G 1DTJA 2BL5A 2CTJA 2CTMA 2OPVA 2YQRA 1VIGA 5C0XG 4JVYA 2JA9A 2JE6I 3L7ZC 1WE8A 3AEVB 4AM3A 2JEAI 4WANA 4QMFB 4AIMA 5K36G 4LIJA 2CTLA 1EC6A 2DGRA 1KHMA 4BA1I 2JZXA 1ZTGA 5JEAG 2OPUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V69 A;  1WVN A;  2CPQ A;  2HH2 A;  3VKE A;  2BA0 A;  2P2R A;  2ANR A;  2ANN A;  2JEB I;  4OO1 G;  1ZZK A;  2JVZ A;  2Z0S A;  2HH3 A;  2CTF A;  1J5K A;  1X4N A;  4IFD G;  2CTK A;  4BA2 I;  2QND A;  4WAL A;  3U1K A;  4B8T A;  1X4M A;  1ZZJ A;  2PY9 A;  1VIH A;  1DT4 A;  1ZZI A;  2E3U A;  1TUA A;  2AXY A;  4NBQ A;  1J4W A;  1K1G A;  2PQU A;  2CTE A;  4JVH A;  2MJH A;  2FMR A;  2NN6 G;  1DTJ A;  2BL5 A;  2CTJ A;  2CTM A;  2OPV A;  2YQR A;  1VIG A;  5C0X G;  4JVY A;  2JA9 A;  2JE6 I;  3L7Z C;  1WE8 A;  3AEV B;  4AM3 A;  2JEA I;  4WAN A;  4QMF B;  4AIM A;  5K36 G;  4LIJ A;  2CTL A;  1EC6 A;  2DGR A;  1KHM A;  4BA1 I;  2JZX A;  1ZTG A;  5JEA G;  2OPU A; 
#chains in the Genus database with same CATH topology
 4DV7 H;  2HH2 A;  3VKE A;  4JV5 H;  4LF5 H;  4DV1 H;  2ANR A;  4JI4 H;  2JEB I;  4OO1 G;  1S20 A;  4G08 A;  2VKC A;  2UXD H;  1X9Z A;  1I6U A;  1VIH A;  3I0P A;  4B8C D;  4X65 H;  4NXM H;  4B3R H;  2LRR A;  1Z2I A;  2M8W A;  3GKU A;  4X62 H;  2CWF A;  3OSS D;  2PQU A;  2O4C A;  4DR2 H;  2FMR A;  4OCH A;  1SEI A;  2UXC H;  5C0X G;  2OPV A;  4JI7 H;  4JI8 H;  1VIG A;  4GKK H;  4JVY A;  2JA9 A;  4JI3 H;  1ODH A;  2UUA H;  1IBL H;  4EC5 A;  4AM3 A;  4DUY H;  4WAN A;  1FJG H;  3KDK A;  4LIJ A;  1N36 H;  2CPM A;  2JZX A;  1KHM A;  2OPU A;  3V69 A;  4DR5 H;  4LF6 H;  2JEA I;  1WVN A;  2CPQ A;  2P2R A;  4JI2 H;  3UOE A;  2LF0 A;  2VQF H;  1ZZK A;  1J5K A;  1AN7 A;  2ZQE A;  2K1H A;  4DR3 H;  2QND A;  3U1K A;  4B8T A;  5IT9 W;  2D9I A;  1ZZJ A;  1DT4 A;  1ZZI A;  4JI5 H;  3KDG A;  2AXY A;  4JYA H;  1J4W A;  1K1G A;  5LMN H;  4JVH A;  4LFA H;  2PT7 G;  2MJH A;  4FJU A;  3RF2 A;  4DV5 H;  4NZT M;  4DV0 H;  4X64 H;  3J81 W;  2CTJ A;  2CTM A;  2YQR A;  1WTJ A;  3EZJ A;  4DV4 H;  5FLX W;  3AEV B;  1PQX A;  4AQY H;  1XNQ H;  1V9N A;  4AIM A;  2FFM A;  5LMU H;  5K36 G;  1IBM H;  2CTL A;  4X66 H;  4OX9 H;  4IFD G;  4YHH H;  4DV3 H;  1F0X A;  4OD6 A;  3OET A;  2JVZ A;  2Z0S A;  3FAU A;  5IWA H;  2CTF A;  3QD7 X;  4DR6 H;  5BR8 H;  4GKJ H;  2CTK A;  2FPH X;  4BA2 I;  2M6Q A;  4WAL A;  3SB1 A;  2PY9 A;  1HNW H;  4K0K H;  3J7A K;  2LTL A;  1NXU A;  4NZR M;  1XMQ H;  4JI1 H;  2F4V H;  4H8A A;  1HNX H;  1XRH A;  2UUB H;  4LFB H;  2BL5 A;  2HHH H;  4DR4 H;  3L7Z C;  2JE6 I;  2UXB H;  2A1S A;  1X0A A;  4QMF B;  1FKA H;  1N34 H;  3GR5 A;  2DGR A;  3JAM W;  5LL6 b;  4B3S H;  4PDB A;  2G8Y A;  4DV6 H;  2UUC H;  4LF9 H;  1VBI A;  1XMO H;  3GAB A;  2CWH A;  5A2Q W;  2BA0 A;  4DR1 H;  1I94 H;  4JI0 H;  4JI6 H;  1N32 H;  4DR7 H;  2ANN A;  4E9J A;  2LTM A;  3J80 W;  4DV2 H;  4NXN H;  2HH3 A;  1X4N A;  4YY3 H;  4LFC H;  1WHR A;  4FJS A;  1X4M A;  3T1H H;  4DUZ H;  2E3U A;  1TUA A;  3NCV A;  4NBQ A;  2VQE H;  1HNZ H;  1J5E H;  2UU9 H;  1UG8 A;  2Y3M A;  2CTE A;  1IBK H;  2ZM6 H;  2NN6 G;  1DTJ A;  4LF7 H;  5DT9 A;  3T1Y H;  1N33 H;  1WE8 A;  2E5L H;  1MSZ A;  4LF4 H;  1HR0 H;  4B3T H;  3OTO H;  1S03 G;  1EC6 A;  4KHP H;  1XNR H;  4LF8 H;  2X06 A;  4BA1 I;  4B3M H;  1ZTG A;  5JEA G;  1V8C A; 
#chains in the Genus database with same CATH homology
 3V69 A;  1WVN A;  2CPQ A;  2HH2 A;  3VKE A;  2BA0 A;  2P2R A;  2ANR A;  2ANN A;  2JEB I;  4OO1 G;  1ZZK A;  2JVZ A;  2Z0S A;  2HH3 A;  2CTF A;  1J5K A;  1X4N A;  4IFD G;  2CTK A;  4BA2 I;  2QND A;  4WAL A;  3U1K A;  4B8T A;  1X4M A;  1ZZJ A;  2PY9 A;  1VIH A;  1DT4 A;  1ZZI A;  2E3U A;  1TUA A;  2AXY A;  4NBQ A;  1J4W A;  1K1G A;  2PQU A;  2CTE A;  4JVH A;  2MJH A;  2FMR A;  2NN6 G;  1DTJ A;  2BL5 A;  2CTJ A;  2CTM A;  2OPV A;  2YQR A;  1VIG A;  5C0X G;  4JVY A;  2JA9 A;  2JE6 I;  3L7Z C;  1WE8 A;  3AEV B;  4AM3 A;  2JEA I;  4WAN A;  4QMF B;  4AIM A;  5K36 G;  4LIJ A;  2CTL A;  1EC6 A;  2DGR A;  1KHM A;  4BA1 I;  2JZX A;  1ZTG A;  5JEA G;  2OPU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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