2ANNA

Crystal structure (i) of nova-1 kh1/kh2 domain tandem with 25 nt rna hairpin
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
175
structure length
148
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQNRVVTVSGEPEQNRKAVELIIQKIQEDP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Rna-binding protein/rna
molecule keywords 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*
publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
total genus 41
structure length 148
sequence length 175
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA02
2BL5A 1TUAA 2OPVA 2HH3A 4AIMA 2MJHA 1DTJA 2CTMA 2OPUA 1VIHA 1WVNA 3VKEA 2JVZA 5K36G 2FMRA 4QMFB 4B8TA 4BA2I 2CTJA 4OO1G 2JA9A 1KHMA 1X4NA 2BA0A 4BA1I 2PQUA 4WALA 2JEAI 4AM3A 1DT4A 2NN6G 2Z0SA 1J5KA 2CTEA 5JEAG 1VIGA 2P2RA 2ANRA 4JVYA 1ZZJA 1EC6A 2JEBI 2YQRA 2HH2A 3AEVB 1ZZIA 1WE8A 3V69A 4NBQA 1ZZKA 1ZTGA 2QNDA 1X4MA 4IFDG 2CTKA 4LIJA 2AXYA 2ANNA 2CTFA 2E3UA 2PY9A 1J4WA 3L7ZC 3U1KA 2DGRA 2CTLA 5C0XG 2JE6I 4JVHA 4WANA 1K1GA 2JZXA 2CPQA
chains in the Genus database with same CATH superfamily
2BL5A 1AN7A 4DV2H 2CTMA 2JVZA 1X9ZA 4B8TA 1HNXH 2ZQEA 2G8YA 2ZM6H 4DV3H 2CTJA 1HNZH 1KHMA 1X4NA 4BA1I 1ODHA 2JEAI 4LFBH 4PDBA 2NN6G 2Z0SA 4B3RH 4DV4H 1S20A 5JEAG 2ANRA 1MSZA 5LMUH 4LF9H 2Y3MA 3AEVB 4JI3H 3T1HH 1ZTGA 2LTMA 4LIJA 2A1SA 2VQEH 4GKKH 3GKUA 1PQXA 4JVHA 2JE6I 1FJGH 1K1GA 1IBLH 4B3SH 4LF4H 4WANA 1HR0H 4DR1H 3OSSD 1XMOH 1J5EH 4JI0H 4LFCH 2UXCH 4B3TH 1VIHA 1WVNA 1WHRA 1SEIA 3NCVA 4AQYH 3J7AK 4JI2H 1I6UA 5K36G 2CWFA 5LMNH 4DUZH 1UG8A 4B8CD 4LF7H 2JA9A 1XNQH 3SB1A 1F0XA 4DR4H 2UXBH 4DV7H 1VIGA 3OETA 4FJUA 4H8AA 1X0AA 1N34H 2YQRA 4K0KH 1EC6A 2LRRA 1ZZIA 4JI7H 1WE8A 3V69A 4G08A 1ZZKA 4IFDG 3JAMW 1X4MA 5FLXW 4X64H 2ANNA 2AXYA 2F4VH 2PY9A 2LTLA 4JV5H 4JYAH 2FPHX 4NZTM 3J80W 4LF8H 2D9IA 1VBIA 5C0XG 2E5LH 4FJSA 4LF6H 4X66H 2FFMA 4DR7H 2VQFH 4JI1H 4E9JA 4B3MH 4OD6A 4DV0H 1DTJA 1S03G 3GR5A 1FKAH 4DR6H 2UU9H 2M8WA 4NXNH 3VKEA 2LF0A 3EZJA 4DV6H 4BA2I 4X62H 4OO1G 1XMQH 5IT9W 2BA0A 2PQUA 3RF2A 1N32H 4AM3A 1DT4A 5A2QW 1XNRH 2CTEA 1Z2IA 4JI5H 4YHHH 3QD7X 1N36H 4OCHA 4DR5H 1IBMH 3FAUA 5IWAH 1IBKH 1XRHA 4NBQA 3T1YH 2QNDA 4NXMH 1N33H 2CTKA 2CTFA 5DT9A 1J4WA 4JI8H 3U1KA 2X06A 1WTJA 2CTLA 2UUBH 4GKJH 3OTOH 1V9NA 1TUAA 2OPVA 2HH3A 3UOEA 4LFAH 1HNWH 4AIMA 3GABA 2MJHA 4DR2H 4JI6H 2OPUA 4OX9H 4LF5H 2K1HA 2FMRA 4QMFB 2M6QA 4X65H 2CPMA 1I94H 4DV5H 4WALA 5LL6b 2HHHH 1J5KA 4EC5A 4NZRM 2P2RA 2UXDH 4JVYA 2O4CA 1ZZJA 3KDKA 1NXUA 2JEBI 2HH2A 4YY3H 5BR8H 2UUCH 1V8CA 3KDGA 3I0PA 4DV1H 2UUAH 2E3UA 2PT7G 4JI4H 3J81W 3L7ZC 2DGRA 4DR3H 4DUYH 4KHPH 2VKCA 2CWHA 2JZXA 2CPQA
chains in the Genus database with same CATH topology
2BL5A 1TUAA 2OPVA 2HH3A 4AIMA 2MJHA 1DTJA 2CTMA 2OPUA 1VIHA 1WVNA 3VKEA 2JVZA 5K36G 2FMRA 4QMFB 4B8TA 4BA2I 2CTJA 4OO1G 2JA9A 1KHMA 1X4NA 2BA0A 4BA1I 2PQUA 4WALA 2JEAI 4AM3A 1DT4A 2NN6G 2Z0SA 1J5KA 2CTEA 5JEAG 1VIGA 2P2RA 2ANRA 4JVYA 1ZZJA 1EC6A 2JEBI 2YQRA 2HH2A 3AEVB 1ZZIA 1WE8A 3V69A 4NBQA 1ZZKA 1ZTGA 2QNDA 1X4MA 4IFDG 2CTKA 4LIJA 2AXYA 2ANNA 2CTFA 2E3UA 2PY9A 1J4WA 3L7ZC 3U1KA 2DGRA 2CTLA 5C0XG 2JE6I 4JVHA 4WANA 1K1GA 2JZXA 2CPQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BL5 A;  1TUA A;  2OPV A;  2HH3 A;  4AIM A;  2MJH A;  1DTJ A;  2CTM A;  2OPU A;  1VIH A;  1WVN A;  3VKE A;  2JVZ A;  5K36 G;  2FMR A;  4QMF B;  4B8T A;  4BA2 I;  2CTJ A;  4OO1 G;  2JA9 A;  1KHM A;  1X4N A;  2BA0 A;  4BA1 I;  2PQU A;  4WAL A;  2JEA I;  4AM3 A;  1DT4 A;  2NN6 G;  2Z0S A;  1J5K A;  2CTE A;  5JEA G;  1VIG A;  2P2R A;  2ANR A;  4JVY A;  1ZZJ A;  1EC6 A;  2JEB I;  2YQR A;  2HH2 A;  3AEV B;  1ZZI A;  1WE8 A;  3V69 A;  4NBQ A;  1ZZK A;  1ZTG A;  2QND A;  1X4M A;  4IFD G;  2CTK A;  4LIJ A;  2AXY A;  2ANN A;  2CTF A;  2E3U A;  2PY9 A;  1J4W A;  3L7Z C;  3U1K A;  2DGR A;  2CTL A;  5C0X G;  2JE6 I;  4JVH A;  4WAN A;  1K1G A;  2JZX A;  2CPQ A; 
#chains in the Genus database with same CATH topology
 2BL5 A;  1AN7 A;  4DV2 H;  2CTM A;  2JVZ A;  1X9Z A;  4B8T A;  1HNX H;  2ZQE A;  2G8Y A;  2ZM6 H;  4DV3 H;  2CTJ A;  1HNZ H;  1KHM A;  1X4N A;  4BA1 I;  1ODH A;  2JEA I;  4LFB H;  4PDB A;  2NN6 G;  2Z0S A;  4B3R H;  4DV4 H;  1S20 A;  5JEA G;  2ANR A;  1MSZ A;  5LMU H;  4LF9 H;  2Y3M A;  3AEV B;  4JI3 H;  3T1H H;  1ZTG A;  2LTM A;  4LIJ A;  2A1S A;  2VQE H;  4GKK H;  3GKU A;  1PQX A;  4JVH A;  2JE6 I;  1FJG H;  1K1G A;  1IBL H;  4B3S H;  4LF4 H;  4WAN A;  1HR0 H;  4DR1 H;  3OSS D;  1XMO H;  1J5E H;  4JI0 H;  4LFC H;  2UXC H;  4B3T H;  1VIH A;  1WVN A;  1WHR A;  1SEI A;  3NCV A;  4AQY H;  3J7A K;  4JI2 H;  1I6U A;  5K36 G;  2CWF A;  5LMN H;  4DUZ H;  1UG8 A;  4B8C D;  4LF7 H;  2JA9 A;  1XNQ H;  3SB1 A;  1F0X A;  4DR4 H;  2UXB H;  4DV7 H;  1VIG A;  3OET A;  4FJU A;  4H8A A;  1X0A A;  1N34 H;  2YQR A;  4K0K H;  1EC6 A;  2LRR A;  1ZZI A;  4JI7 H;  1WE8 A;  3V69 A;  4G08 A;  1ZZK A;  4IFD G;  3JAM W;  1X4M A;  5FLX W;  4X64 H;  2ANN A;  2AXY A;  2F4V H;  2PY9 A;  2LTL A;  4JV5 H;  4JYA H;  2FPH X;  4NZT M;  3J80 W;  4LF8 H;  2D9I A;  1VBI A;  5C0X G;  2E5L H;  4FJS A;  4LF6 H;  4X66 H;  2FFM A;  4DR7 H;  2VQF H;  4JI1 H;  4E9J A;  4B3M H;  4OD6 A;  4DV0 H;  1DTJ A;  1S03 G;  3GR5 A;  1FKA H;  4DR6 H;  2UU9 H;  2M8W A;  4NXN H;  3VKE A;  2LF0 A;  3EZJ A;  4DV6 H;  4BA2 I;  4X62 H;  4OO1 G;  1XMQ H;  5IT9 W;  2BA0 A;  2PQU A;  3RF2 A;  1N32 H;  4AM3 A;  1DT4 A;  5A2Q W;  1XNR H;  2CTE A;  1Z2I A;  4JI5 H;  4YHH H;  3QD7 X;  1N36 H;  4OCH A;  4DR5 H;  1IBM H;  3FAU A;  5IWA H;  1IBK H;  1XRH A;  4NBQ A;  3T1Y H;  2QND A;  4NXM H;  1N33 H;  2CTK A;  2CTF A;  5DT9 A;  1J4W A;  4JI8 H;  3U1K A;  2X06 A;  1WTJ A;  2CTL A;  2UUB H;  4GKJ H;  3OTO H;  1V9N A;  1TUA A;  2OPV A;  2HH3 A;  3UOE A;  4LFA H;  1HNW H;  4AIM A;  3GAB A;  2MJH A;  4DR2 H;  4JI6 H;  2OPU A;  4OX9 H;  4LF5 H;  2K1H A;  2FMR A;  4QMF B;  2M6Q A;  4X65 H;  2CPM A;  1I94 H;  4DV5 H;  4WAL A;  5LL6 b;  2HHH H;  1J5K A;  4EC5 A;  4NZR M;  2P2R A;  2UXD H;  4JVY A;  2O4C A;  1ZZJ A;  3KDK A;  1NXU A;  2JEB I;  2HH2 A;  4YY3 H;  5BR8 H;  2UUC H;  1V8C A;  3KDG A;  3I0P A;  4DV1 H;  2UUA H;  2E3U A;  2PT7 G;  4JI4 H;  3J81 W;  3L7Z C;  2DGR A;  4DR3 H;  4DUY H;  4KHP H;  2VKC A;  2CWH A;  2JZX A;  2CPQ A; 
#chains in the Genus database with same CATH homology
 2BL5 A;  1TUA A;  2OPV A;  2HH3 A;  4AIM A;  2MJH A;  1DTJ A;  2CTM A;  2OPU A;  1VIH A;  1WVN A;  3VKE A;  2JVZ A;  5K36 G;  2FMR A;  4QMF B;  4B8T A;  4BA2 I;  2CTJ A;  4OO1 G;  2JA9 A;  1KHM A;  1X4N A;  2BA0 A;  4BA1 I;  2PQU A;  4WAL A;  2JEA I;  4AM3 A;  1DT4 A;  2NN6 G;  2Z0S A;  1J5K A;  2CTE A;  5JEA G;  1VIG A;  2P2R A;  2ANR A;  4JVY A;  1ZZJ A;  1EC6 A;  2JEB I;  2YQR A;  2HH2 A;  3AEV B;  1ZZI A;  1WE8 A;  3V69 A;  4NBQ A;  1ZZK A;  1ZTG A;  2QND A;  1X4M A;  4IFD G;  2CTK A;  4LIJ A;  2AXY A;  2ANN A;  2CTF A;  2E3U A;  2PY9 A;  1J4W A;  3L7Z C;  3U1K A;  2DGR A;  2CTL A;  5C0X G;  2JE6 I;  4JVH A;  4WAN A;  1K1G A;  2JZX A;  2CPQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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