2ANNA

Crystal structure (i) of nova-1 kh1/kh2 domain tandem with 25 nt rna hairpin
Total Genus 41
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
175
structure length
148
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQNRVVTVSGEPEQNRKAVELIIQKIQEDP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Rna-binding protein/rna
molecule keywords 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*
total genus 41
structure length 148
sequence length 175
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA02
2MJHA 1VIGA 4QMFB 2ANNA 1ZZKA 2BA0A 2HH3A 2E3UA 2NN6G 2JE6I 2QNDA 2BL5A 4AM3A 3V69A 4JVHA 1ZZJA 1TUAA 3AEVB 1ZTGA 5K36G 1DTJA 2FMRA 1X4MA 3L7ZC 2CPQA 2PQUA 4JVYA 1EC6A 1X4NA 1KHMA 2CTFA 1WE8A 2JA9A 2AXYA 1WVNA 1K1GA 4WANA 3VKEA 2PY9A 4LIJA 4IFDG 4WALA 2CTLA 1J5KA 2ANRA 2P2RA 1VIHA 2OPVA 3U1KA 2JEAI 2CTMA 1ZZIA 2CTEA 2DGRA 2HH2A 4BA1I 4B8TA 1J4WA 1DT4A 4NBQA 2Z0SA 4OO1G 2JZXA 2OPUA 5JEAG 4BA2I 2JVZA 2YQRA 2CTJA 2JEBI 4AIMA 2CTKA 5C0XG
chains in the Genus database with same CATH superfamily
4NXMH 4DV0H 1V9NA 1VIGA 4QMFB 4NZRM 2HH3A 4DUZH 5IT9W 2QNDA 1PQXA 2BL5A 2VQFH 4DV1H 1WTJA 4GKKH 1DTJA 1HNXH 1EC6A 2PQUA 1UG8A 2LRRA 2CTFA 2VQEH 2A1SA 2CWFA 1N34H 4PDBA 2UXBH 4LF7H 4NXNH 1HNWH 4DV4H 4JYAH 3OTOH 4DV6H 4DR5H 2OPVA 1MSZA 1ZZIA 4JI0H 1J4WA 2Z0SA 4X62H 1VBIA 4B3MH 4DR7H 5JEAG 4BA2I 1X0AA 2CTKA 2G8YA 4G08A 1XMOH 4LF6H 4LFAH 2F4VH 4JV5H 4B3TH 2MJHA 2ANNA 1ZZKA 2E5LH 2NN6G 5A2QW 1I6UA 3J80W 3V69A 3T1HH 4JI4H 2D9IA 1ZZJA 2CWHA 4JI3H 2O4CA 4DR4H 1X4MA 4H8AA 2CPQA 1X4NA 1N32H 3J7AK 5DT9A 1S20A 2JA9A 3GR5A 1WVNA 3NCVA 4WANA 2PY9A 4OX9H 4IFDG 3KDGA 4DR2H 4KHPH 5FLXW 2CTLA 4WALA 4X64H 1X9ZA 5LMUH 5LMNH 3OSSD 4YY3H 1HNZH 2P2RA 2CTMA 2JEAI 1XNQH 1J5EH 1WHRA 4OO1G 4DV5H 2LTLA 4YHHH 2CTJA 1FJGH 5C0XG 2LTMA 1S03G 2M6QA 4GKJH 4B8CD 4LF9H 1ODHA 5BR8H 2UXCH 2JE6I 1V8CA 4JVHA 4AQYH 2UUCH 5IWAH 3AEVB 3J81W 2FMRA 3EZJA 3OETA 5LL6b 4DUYH 1IBMH 4K0KH 4JI1H 4JI7H 4EC5A 4LF5H 3GKUA 1K1GA 4FJUA 3VKEA 1N36H 4FJSA 4B3RH 4LIJA 4B3SH 4LFBH 1IBLH 2FPHX 4DV3H 4DR3H 1J5KA 2ANRA 4JI5H 1VIHA 3T1YH 1HR0H 2VKCA 4DV7H 2CTEA 4B8TA 4BA1I 1IBKH 2M8WA 4JI6H 2JZXA 2FFMA 4JI8H 2YQRA 4JI2H 4AIMA 4LF8H 1I94H 3KDKA 3SB1A 4DR1H 4LFCH 4NZTM 1FKAH 2X06A 1N33H 2BA0A 2LF0A 2UUAH 2E3UA 1NXUA 4AM3A 4X65H 1XMQH 3FAUA 4OCHA 1TUAA 1ZTGA 5K36G 3L7ZC 1XRHA 4JVYA 1KHMA 3GABA 3RF2A 4DV2H 1WE8A 1Z2IA 4X66H 3UOEA 3I0PA 2AXYA 2UU9H 1XNRH 2PT7G 1AN7A 4DR6H 2UUBH 1F0XA 3JAMW 2CPMA 4OD6A 2UXDH 1SEIA 3U1KA 2DGRA 2HH2A 4LF4H 1DT4A 4NBQA 2ZM6H 2OPUA 2Y3MA 2JVZA 2ZQEA 2JEBI 2HHHH 4E9JA 2K1HA 3QD7X
chains in the Genus database with same CATH topology
2MJHA 1VIGA 4QMFB 2ANNA 1ZZKA 2BA0A 2HH3A 2E3UA 2NN6G 2JE6I 2QNDA 2BL5A 4AM3A 3V69A 4JVHA 1ZZJA 1TUAA 3AEVB 1ZTGA 5K36G 1DTJA 2FMRA 1X4MA 3L7ZC 2CPQA 2PQUA 4JVYA 1EC6A 1X4NA 1KHMA 2CTFA 1WE8A 2JA9A 2AXYA 1WVNA 1K1GA 4WANA 3VKEA 2PY9A 4LIJA 4IFDG 4WALA 2CTLA 1J5KA 2ANRA 2P2RA 1VIHA 2OPVA 3U1KA 2JEAI 2CTMA 1ZZIA 2CTEA 2DGRA 2HH2A 4BA1I 4B8TA 1J4WA 1DT4A 4NBQA 2Z0SA 4OO1G 2JZXA 2OPUA 5JEAG 4BA2I 2JVZA 2YQRA 2CTJA 2JEBI 4AIMA 2CTKA 5C0XG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MJH A;  1VIG A;  4QMF B;  2ANN A;  1ZZK A;  2BA0 A;  2HH3 A;  2E3U A;  2NN6 G;  2JE6 I;  2QND A;  2BL5 A;  4AM3 A;  3V69 A;  4JVH A;  1ZZJ A;  1TUA A;  3AEV B;  1ZTG A;  5K36 G;  1DTJ A;  2FMR A;  1X4M A;  3L7Z C;  2CPQ A;  2PQU A;  4JVY A;  1EC6 A;  1X4N A;  1KHM A;  2CTF A;  1WE8 A;  2JA9 A;  2AXY A;  1WVN A;  1K1G A;  4WAN A;  3VKE A;  2PY9 A;  4LIJ A;  4IFD G;  4WAL A;  2CTL A;  1J5K A;  2ANR A;  2P2R A;  1VIH A;  2OPV A;  3U1K A;  2JEA I;  2CTM A;  1ZZI A;  2CTE A;  2DGR A;  2HH2 A;  4BA1 I;  4B8T A;  1J4W A;  1DT4 A;  4NBQ A;  2Z0S A;  4OO1 G;  2JZX A;  2OPU A;  5JEA G;  4BA2 I;  2JVZ A;  2YQR A;  2CTJ A;  2JEB I;  4AIM A;  2CTK A;  5C0X G; 
#chains in the Genus database with same CATH topology
 4NXM H;  4DV0 H;  1V9N A;  1VIG A;  4QMF B;  4NZR M;  2HH3 A;  4DUZ H;  5IT9 W;  2QND A;  1PQX A;  2BL5 A;  2VQF H;  4DV1 H;  1WTJ A;  4GKK H;  1DTJ A;  1HNX H;  1EC6 A;  2PQU A;  1UG8 A;  2LRR A;  2CTF A;  2VQE H;  2A1S A;  2CWF A;  1N34 H;  4PDB A;  2UXB H;  4LF7 H;  4NXN H;  1HNW H;  4DV4 H;  4JYA H;  3OTO H;  4DV6 H;  4DR5 H;  2OPV A;  1MSZ A;  1ZZI A;  4JI0 H;  1J4W A;  2Z0S A;  4X62 H;  1VBI A;  4B3M H;  4DR7 H;  5JEA G;  4BA2 I;  1X0A A;  2CTK A;  2G8Y A;  4G08 A;  1XMO H;  4LF6 H;  4LFA H;  2F4V H;  4JV5 H;  4B3T H;  2MJH A;  2ANN A;  1ZZK A;  2E5L H;  2NN6 G;  5A2Q W;  1I6U A;  3J80 W;  3V69 A;  3T1H H;  4JI4 H;  2D9I A;  1ZZJ A;  2CWH A;  4JI3 H;  2O4C A;  4DR4 H;  1X4M A;  4H8A A;  2CPQ A;  1X4N A;  1N32 H;  3J7A K;  5DT9 A;  1S20 A;  2JA9 A;  3GR5 A;  1WVN A;  3NCV A;  4WAN A;  2PY9 A;  4OX9 H;  4IFD G;  3KDG A;  4DR2 H;  4KHP H;  5FLX W;  2CTL A;  4WAL A;  4X64 H;  1X9Z A;  5LMU H;  5LMN H;  3OSS D;  4YY3 H;  1HNZ H;  2P2R A;  2CTM A;  2JEA I;  1XNQ H;  1J5E H;  1WHR A;  4OO1 G;  4DV5 H;  2LTL A;  4YHH H;  2CTJ A;  1FJG H;  5C0X G;  2LTM A;  1S03 G;  2M6Q A;  4GKJ H;  4B8C D;  4LF9 H;  1ODH A;  5BR8 H;  2UXC H;  2JE6 I;  1V8C A;  4JVH A;  4AQY H;  2UUC H;  5IWA H;  3AEV B;  3J81 W;  2FMR A;  3EZJ A;  3OET A;  5LL6 b;  4DUY H;  1IBM H;  4K0K H;  4JI1 H;  4JI7 H;  4EC5 A;  4LF5 H;  3GKU A;  1K1G A;  4FJU A;  3VKE A;  1N36 H;  4FJS A;  4B3R H;  4LIJ A;  4B3S H;  4LFB H;  1IBL H;  2FPH X;  4DV3 H;  4DR3 H;  1J5K A;  2ANR A;  4JI5 H;  1VIH A;  3T1Y H;  1HR0 H;  2VKC A;  4DV7 H;  2CTE A;  4B8T A;  4BA1 I;  1IBK H;  2M8W A;  4JI6 H;  2JZX A;  2FFM A;  4JI8 H;  2YQR A;  4JI2 H;  4AIM A;  4LF8 H;  1I94 H;  3KDK A;  3SB1 A;  4DR1 H;  4LFC H;  4NZT M;  1FKA H;  2X06 A;  1N33 H;  2BA0 A;  2LF0 A;  2UUA H;  2E3U A;  1NXU A;  4AM3 A;  4X65 H;  1XMQ H;  3FAU A;  4OCH A;  1TUA A;  1ZTG A;  5K36 G;  3L7Z C;  1XRH A;  4JVY A;  1KHM A;  3GAB A;  3RF2 A;  4DV2 H;  1WE8 A;  1Z2I A;  4X66 H;  3UOE A;  3I0P A;  2AXY A;  2UU9 H;  1XNR H;  2PT7 G;  1AN7 A;  4DR6 H;  2UUB H;  1F0X A;  3JAM W;  2CPM A;  4OD6 A;  2UXD H;  1SEI A;  3U1K A;  2DGR A;  2HH2 A;  4LF4 H;  1DT4 A;  4NBQ A;  2ZM6 H;  2OPU A;  2Y3M A;  2JVZ A;  2ZQE A;  2JEB I;  2HHH H;  4E9J A;  2K1H A;  3QD7 X; 
#chains in the Genus database with same CATH homology
 2MJH A;  1VIG A;  4QMF B;  2ANN A;  1ZZK A;  2BA0 A;  2HH3 A;  2E3U A;  2NN6 G;  2JE6 I;  2QND A;  2BL5 A;  4AM3 A;  3V69 A;  4JVH A;  1ZZJ A;  1TUA A;  3AEV B;  1ZTG A;  5K36 G;  1DTJ A;  2FMR A;  1X4M A;  3L7Z C;  2CPQ A;  2PQU A;  4JVY A;  1EC6 A;  1X4N A;  1KHM A;  2CTF A;  1WE8 A;  2JA9 A;  2AXY A;  1WVN A;  1K1G A;  4WAN A;  3VKE A;  2PY9 A;  4LIJ A;  4IFD G;  4WAL A;  2CTL A;  1J5K A;  2ANR A;  2P2R A;  1VIH A;  2OPV A;  3U1K A;  2JEA I;  2CTM A;  1ZZI A;  2CTE A;  2DGR A;  2HH2 A;  4BA1 I;  4B8T A;  1J4W A;  1DT4 A;  4NBQ A;  2Z0S A;  4OO1 G;  2JZX A;  2OPU A;  5JEA G;  4BA2 I;  2JVZ A;  2YQR A;  2CTJ A;  2JEB I;  4AIM A;  2CTK A;  5C0X G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...