2ANNA

Crystal structure (i) of nova-1 kh1/kh2 domain tandem with 25 nt rna hairpin
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
175
structure length
148
Chain Sequence
b'GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQNRVVTVSGEPEQNRKAVELIIQKIQEDP'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*
publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Rna-binding protein/rna
total genus 41
structure length 148
sequence length 175
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA02
3L7ZC 1KHMA 2FMRA 1ZTGA 1ZZJA 4IFDG 2CTJA 2CTMA 2P2RA 1X4NA 2OPUA 1K1GA 4WANA 1ZZKA 1J4WA 2MJHA 3AEVB 2JVZA 2YQRA 1TUAA 2JA9A 5C0XG 2HH3A 2JE6I 3V69A 1VIHA 4OO1G 4JVHA 4NBQA 2E3UA 4LIJA 2DGRA 2JZXA 2CPQA 2NN6G 2Z0SA 2ANRA 4WALA 2HH2A 4BA1I 5K36G 2QNDA 1DT4A 1J5KA 2JEAI 1VIGA 2CTFA 2ANNA 1EC6A 2PQUA 2OPVA 1ZZIA 4JVYA 3U1KA 5JEAG 2BA0A 2CTEA 4BA2I 2JEBI 2PY9A 2BL5A 2AXYA 1DTJA 4AM3A 1WE8A 1WVNA 2CTKA 4B8TA 4QMFB 2CTLA 3VKEA 1X4MA 4AIMA
chains in the Genus database with same CATH superfamily
4YHHH 5LMNH 1ZTGA 1K1GA 4WANA 4X62H 1ZZKA 2ZM6H 2UUAH 1UG8A 2E5LH 2YQRA 4JI5H 2M6QA 2VKCA 5C0XG 2HH3A 2JE6I 4OO1G 4DR2H 1X0AA 5LL6b 2DGRA 1S20A 2CPQA 2JZXA 2Z0SA 1XNQH 4X64H 2HH2A 4FJSA 2UXDH 3RF2A 1XMOH 1NXUA 1N33H 4B8CD 4DUYH 4DV5H 1V8CA 3J80W 2VQFH 1I94H 2PQUA 5JEAG 2F4VH 1ODHA 2CTEA 1HNZH 1VBIA 2CWFA 2X06A 1XMQH 4JI1H 1HNXH 4FJUA 1N36H 2CTKA 3SB1A 4DV2H 2VQEH 4JI3H 3I0PA 4AIMA 4LF9H 2JEAI 4GKKH 2CPMA 1S03G 2O4CA 1N34H 1X4NA 1IBMH 3OETA 4LF4H 3JAMW 4LF6H 3AEVB 4DR7H 3FAUA 2JVZA 4OX9H 4X66H 4NZRM 2LTMA 4JVHA 2UXCH 1V9NA 1VIHA 3OSSD 4NZTM 2ZQEA 4B3TH 2NN6G 4DR6H 4OD6A 4LFCH 2UU9H 4DV6H 5A2QW 1WTJA 3J81W 1VIGA 1J5EH 2ANNA 4PDBA 4B3MH 4EC5A 4LF8H 4GKJH 1EC6A 2G8YA 2Y3MA 2UUBH 2BA0A 3GABA 4BA2I 2JEBI 5LMUH 4DV7H 2AXYA 1DTJA 1WE8A 1WVNA 4QMFB 4JI0H 2FPHX 1X4MA 3T1HH 3J7AK 3L7ZC 1KHMA 2CTMA 4JI7H 4X65H 1J4WA 2MJHA 4LFBH 4B3RH 1FJGH 4LF5H 4JYAH 2JA9A 4LF7H 1HNWH 4DV4H 2LF0A 5FLXW 4B3SH 1F0XA 2E3UA 4LIJA 3KDKA 5IT9W 2LTLA 4WALA 4DV3H 2HHHH 2A1SA 4BA1I 2K1HA 3GKUA 4KHPH 4NXNH 5K36G 2CWHA 1J5KA 2CTFA 3QD7X 2M8WA 3NCVA 3GR5A 1ZZIA 1AN7A 4DV1H 3U1KA 1XNRH 4JV5H 1I6UA 3UOEA 4LFAH 1X9ZA 1WHRA 3KDGA 2BL5A 1FKAH 2PY9A 5IWAH 4G08A 4B8TA 2CTLA 4JI6H 1HR0H 2FMRA 4YY3H 3EZJA 1ZZJA 4IFDG 2CTJA 2P2RA 2OPUA 4H8AA 1XRHA 4K0KH 1TUAA 1IBLH 1MSZA 1IBKH 5BR8H 4NXMH 3V69A 3OTOH 4DR1H 4NBQA 4DR4H 2PT7G 2ANRA 1Z2IA 4JI2H 4DV0H 1SEIA 2LRRA 4OCHA 2QNDA 1DT4A 4E9JA 2FFMA 4DR5H 4JI4H 2OPVA 1PQXA 4JVYA 1N32H 2D9IA 2UXBH 4DR3H 4AM3A 4DUZH 2UUCH 3T1YH 3VKEA 4AQYH 5DT9A 4JI8H
chains in the Genus database with same CATH topology
3L7ZC 1KHMA 2FMRA 1ZTGA 1ZZJA 4IFDG 2CTJA 2CTMA 2P2RA 1X4NA 2OPUA 1K1GA 4WANA 1ZZKA 1J4WA 2MJHA 3AEVB 2JVZA 2YQRA 1TUAA 2JA9A 5C0XG 2HH3A 2JE6I 3V69A 1VIHA 4OO1G 4JVHA 4NBQA 2E3UA 4LIJA 2DGRA 2JZXA 2CPQA 2NN6G 2Z0SA 2ANRA 4WALA 2HH2A 4BA1I 5K36G 2QNDA 1DT4A 1J5KA 2JEAI 1VIGA 2CTFA 2ANNA 1EC6A 2PQUA 2OPVA 1ZZIA 4JVYA 3U1KA 5JEAG 2BA0A 2CTEA 4BA2I 2JEBI 2PY9A 2BL5A 2AXYA 1DTJA 4AM3A 1WE8A 1WVNA 2CTKA 4B8TA 4QMFB 2CTLA 3VKEA 1X4MA 4AIMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L7Z C;  1KHM A;  2FMR A;  1ZTG A;  1ZZJ A;  4IFD G;  2CTJ A;  2CTM A;  2P2R A;  1X4N A;  2OPU A;  1K1G A;  4WAN A;  1ZZK A;  1J4W A;  2MJH A;  3AEV B;  2JVZ A;  2YQR A;  1TUA A;  2JA9 A;  5C0X G;  2HH3 A;  2JE6 I;  3V69 A;  1VIH A;  4OO1 G;  4JVH A;  4NBQ A;  2E3U A;  4LIJ A;  2DGR A;  2JZX A;  2CPQ A;  2NN6 G;  2Z0S A;  2ANR A;  4WAL A;  2HH2 A;  4BA1 I;  5K36 G;  2QND A;  1DT4 A;  1J5K A;  2JEA I;  1VIG A;  2CTF A;  2ANN A;  1EC6 A;  2PQU A;  2OPV A;  1ZZI A;  4JVY A;  3U1K A;  5JEA G;  2BA0 A;  2CTE A;  4BA2 I;  2JEB I;  2PY9 A;  2BL5 A;  2AXY A;  1DTJ A;  4AM3 A;  1WE8 A;  1WVN A;  2CTK A;  4B8T A;  4QMF B;  2CTL A;  3VKE A;  1X4M A;  4AIM A; 
#chains in the Genus database with same CATH topology
 4YHH H;  5LMN H;  1ZTG A;  1K1G A;  4WAN A;  4X62 H;  1ZZK A;  2ZM6 H;  2UUA H;  1UG8 A;  2E5L H;  2YQR A;  4JI5 H;  2M6Q A;  2VKC A;  5C0X G;  2HH3 A;  2JE6 I;  4OO1 G;  4DR2 H;  1X0A A;  5LL6 b;  2DGR A;  1S20 A;  2CPQ A;  2JZX A;  2Z0S A;  1XNQ H;  4X64 H;  2HH2 A;  4FJS A;  2UXD H;  3RF2 A;  1XMO H;  1NXU A;  1N33 H;  4B8C D;  4DUY H;  4DV5 H;  1V8C A;  3J80 W;  2VQF H;  1I94 H;  2PQU A;  5JEA G;  2F4V H;  1ODH A;  2CTE A;  1HNZ H;  1VBI A;  2CWF A;  2X06 A;  1XMQ H;  4JI1 H;  1HNX H;  4FJU A;  1N36 H;  2CTK A;  3SB1 A;  4DV2 H;  2VQE H;  4JI3 H;  3I0P A;  4AIM A;  4LF9 H;  2JEA I;  4GKK H;  2CPM A;  1S03 G;  2O4C A;  1N34 H;  1X4N A;  1IBM H;  3OET A;  4LF4 H;  3JAM W;  4LF6 H;  3AEV B;  4DR7 H;  3FAU A;  2JVZ A;  4OX9 H;  4X66 H;  4NZR M;  2LTM A;  4JVH A;  2UXC H;  1V9N A;  1VIH A;  3OSS D;  4NZT M;  2ZQE A;  4B3T H;  2NN6 G;  4DR6 H;  4OD6 A;  4LFC H;  2UU9 H;  4DV6 H;  5A2Q W;  1WTJ A;  3J81 W;  1VIG A;  1J5E H;  2ANN A;  4PDB A;  4B3M H;  4EC5 A;  4LF8 H;  4GKJ H;  1EC6 A;  2G8Y A;  2Y3M A;  2UUB H;  2BA0 A;  3GAB A;  4BA2 I;  2JEB I;  5LMU H;  4DV7 H;  2AXY A;  1DTJ A;  1WE8 A;  1WVN A;  4QMF B;  4JI0 H;  2FPH X;  1X4M A;  3T1H H;  3J7A K;  3L7Z C;  1KHM A;  2CTM A;  4JI7 H;  4X65 H;  1J4W A;  2MJH A;  4LFB H;  4B3R H;  1FJG H;  4LF5 H;  4JYA H;  2JA9 A;  4LF7 H;  1HNW H;  4DV4 H;  2LF0 A;  5FLX W;  4B3S H;  1F0X A;  2E3U A;  4LIJ A;  3KDK A;  5IT9 W;  2LTL A;  4WAL A;  4DV3 H;  2HHH H;  2A1S A;  4BA1 I;  2K1H A;  3GKU A;  4KHP H;  4NXN H;  5K36 G;  2CWH A;  1J5K A;  2CTF A;  3QD7 X;  2M8W A;  3NCV A;  3GR5 A;  1ZZI A;  1AN7 A;  4DV1 H;  3U1K A;  1XNR H;  4JV5 H;  1I6U A;  3UOE A;  4LFA H;  1X9Z A;  1WHR A;  3KDG A;  2BL5 A;  1FKA H;  2PY9 A;  5IWA H;  4G08 A;  4B8T A;  2CTL A;  4JI6 H;  1HR0 H;  2FMR A;  4YY3 H;  3EZJ A;  1ZZJ A;  4IFD G;  2CTJ A;  2P2R A;  2OPU A;  4H8A A;  1XRH A;  4K0K H;  1TUA A;  1IBL H;  1MSZ A;  1IBK H;  5BR8 H;  4NXM H;  3V69 A;  3OTO H;  4DR1 H;  4NBQ A;  4DR4 H;  2PT7 G;  2ANR A;  1Z2I A;  4JI2 H;  4DV0 H;  1SEI A;  2LRR A;  4OCH A;  2QND A;  1DT4 A;  4E9J A;  2FFM A;  4DR5 H;  4JI4 H;  2OPV A;  1PQX A;  4JVY A;  1N32 H;  2D9I A;  2UXB H;  4DR3 H;  4AM3 A;  4DUZ H;  2UUC H;  3T1Y H;  3VKE A;  4AQY H;  5DT9 A;  4JI8 H; 
#chains in the Genus database with same CATH homology
 3L7Z C;  1KHM A;  2FMR A;  1ZTG A;  1ZZJ A;  4IFD G;  2CTJ A;  2CTM A;  2P2R A;  1X4N A;  2OPU A;  1K1G A;  4WAN A;  1ZZK A;  1J4W A;  2MJH A;  3AEV B;  2JVZ A;  2YQR A;  1TUA A;  2JA9 A;  5C0X G;  2HH3 A;  2JE6 I;  3V69 A;  1VIH A;  4OO1 G;  4JVH A;  4NBQ A;  2E3U A;  4LIJ A;  2DGR A;  2JZX A;  2CPQ A;  2NN6 G;  2Z0S A;  2ANR A;  4WAL A;  2HH2 A;  4BA1 I;  5K36 G;  2QND A;  1DT4 A;  1J5K A;  2JEA I;  1VIG A;  2CTF A;  2ANN A;  1EC6 A;  2PQU A;  2OPV A;  1ZZI A;  4JVY A;  3U1K A;  5JEA G;  2BA0 A;  2CTE A;  4BA2 I;  2JEB I;  2PY9 A;  2BL5 A;  2AXY A;  1DTJ A;  4AM3 A;  1WE8 A;  1WVN A;  2CTK A;  4B8T A;  4QMF B;  2CTL A;  3VKE A;  1X4M A;  4AIM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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