4H8AA

Crystal structure of ureidoglycolate dehydrogenase in binary complex with nadh
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
337
structure length
337
Chain Sequence
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Ureidoglycolate dehydrogenase
total genus 113
structure length 337
sequence length 337
chains with identical sequence B
ec nomenclature ec 1.1.1.350: Ureidoglycolate dehydrogenase (NAD(+)).
pdb deposition date 2012-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 4h8aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 4h8aA02
4FJUA 1VBIA 1V9NA 1X0AA 1Z2IA 2G8YA 3I0PA 2CWHA 4FJSA 3UOEA 2CWFA 1WTJA 2X06A 1XRHA 1S20A 1NXUA 4H8AA
chains in the Genus database with same CATH superfamily
4GKJH 1IBKH 1N32H 2CTFA 4B8CD 1WE8A 1FKAH 3KDGA 4NBQA 1K1GA 4JI3H 1UG8A 1N34H 4JV5H 2PQUA 4NXNH 1HR0H 4JI7H 4LF7H 4DR5H 1ZZIA 4DV3H 2LTMA 1ZZJA 2UU9H 2ZM6H 4JVHA 4LF8H 3KDKA 4G08A 2JEBI 5LMUH 4KHPH 2PT7G 2ANRA 3RF2A 2HH2A 2UUCH 2CTLA 2CTMA 2CTEA 4X64H 4LFAH 5IT9W 4WANA 1SEIA 4DR2H 2X06A 4JI0H 3U1KA 4FJSA 2M8WA 4OD6A 2AXYA 4NZRM 5IWAH 4GKKH 3JAMW 2JZXA 4DR7H 2K1HA 1HNXH 4DV1H 4AQYH 5LMNH 4YY3H 2D9IA 4DV2H 2LRRA 4YHHH 1KHMA 2Z0SA 3EZJA 1F0XA 2VQFH 1WVNA 2JE6I 4JI5H 4DV0H 3OTOH 4LIJA 4LF4H 2UXCH 1XMQH 4LFCH 4LFBH 2CTJA 2UXBH 4B8TA 1XRHA 1HNZH 1I6UA 1J5KA 2UUBH 4EC5A 1VBIA 4E9JA 4AM3A 2P2RA 2M6QA 4B3MH 2JEAI 3AEVB 2JVZA 5FLXW 1S20A 4DUZH 3QD7X 4DR1H 2YQRA 1VIGA 1IBLH 4JYAH 1X0AA 2CTKA 2PY9A 2FMRA 4DUYH 1VIHA 1WTJA 1EC6A 3GR5A 2OPVA 4AIMA 1TUAA 3FAUA 2ANNA 4IFDG 1AN7A 1XNRH 2BL5A 3VKEA 5JEAG 4B3TH 2HHHH 2BA0A 4BA1I 2E5LH 2CWHA 3UOEA 2MJHA 1IBMH 1X4MA 4X66H 4JI1H 4DR6H 1NXUA 4X65H 1I94H 1Z2IA 2G8YA 3L7ZC 4X62H 3SB1A 2LTLA 3T1HH 4B3RH 4B3SH 2A1SA 4JI4H 2O4CA 2VQEH 4K0KH 4OO1G 2FPHX 1J4WA 1DT4A 4H8AA 4NZTM 4PDBA 1V8CA 4DV6H 1N36H 2LF0A 2UUAH 5DT9A 2UXDH 4JI2H 1ZZKA 3J81W 1PQXA 4DR3H 2NN6G 2HH3A 2CWFA 1XMOH 1WHRA 1ZTGA 4DR4H 5LL6b 3NCVA 2FFMA 3J7AK 2E3UA 1V9NA 1S03G 3GKUA 3OSSD 1FJGH 3J80W 4NXMH 2JA9A 4WALA 1XNQH 4JI6H 1J5EH 1X4NA 3T1YH 2CPMA 4FJUA 4QMFB 4OX9H 2VKCA 3I0PA 4JI8H 4OCHA 4DV4H 3GABA 2QNDA 4BA2I 4JVYA 2ZQEA 4DV7H 2Y3MA 2CPQA 1DTJA 3OETA 5BR8H 5A2QW 4LF9H 4DV5H 4LF5H 5C0XG 1HNWH 1ODHA 3V69A 2F4VH 1X9ZA 5K36G 1N33H 4LF6H 1MSZA 2OPUA 2DGRA
chains in the Genus database with same CATH topology
4FJUA 1VBIA 1V9NA 1X0AA 1Z2IA 2G8YA 3I0PA 2CWHA 4FJSA 3UOEA 2CWFA 1WTJA 2X06A 1XRHA 1S20A 1NXUA 4H8AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FJU A;  1VBI A;  1V9N A;  1X0A A;  1Z2I A;  2G8Y A;  3I0P A;  2CWH A;  4FJS A;  3UOE A;  2CWF A;  1WTJ A;  2X06 A;  1XRH A;  1S20 A;  1NXU A;  4H8A A; 
#chains in the Genus database with same CATH topology
 4GKJ H;  1IBK H;  1N32 H;  2CTF A;  4B8C D;  1WE8 A;  1FKA H;  3KDG A;  4NBQ A;  1K1G A;  4JI3 H;  1UG8 A;  1N34 H;  4JV5 H;  2PQU A;  4NXN H;  1HR0 H;  4JI7 H;  4LF7 H;  4DR5 H;  1ZZI A;  4DV3 H;  2LTM A;  1ZZJ A;  2UU9 H;  2ZM6 H;  4JVH A;  4LF8 H;  3KDK A;  4G08 A;  2JEB I;  5LMU H;  4KHP H;  2PT7 G;  2ANR A;  3RF2 A;  2HH2 A;  2UUC H;  2CTL A;  2CTM A;  2CTE A;  4X64 H;  4LFA H;  5IT9 W;  4WAN A;  1SEI A;  4DR2 H;  2X06 A;  4JI0 H;  3U1K A;  4FJS A;  2M8W A;  4OD6 A;  2AXY A;  4NZR M;  5IWA H;  4GKK H;  3JAM W;  2JZX A;  4DR7 H;  2K1H A;  1HNX H;  4DV1 H;  4AQY H;  5LMN H;  4YY3 H;  2D9I A;  4DV2 H;  2LRR A;  4YHH H;  1KHM A;  2Z0S A;  3EZJ A;  1F0X A;  2VQF H;  1WVN A;  2JE6 I;  4JI5 H;  4DV0 H;  3OTO H;  4LIJ A;  4LF4 H;  2UXC H;  1XMQ H;  4LFC H;  4LFB H;  2CTJ A;  2UXB H;  4B8T A;  1XRH A;  1HNZ H;  1I6U A;  1J5K A;  2UUB H;  4EC5 A;  1VBI A;  4E9J A;  4AM3 A;  2P2R A;  2M6Q A;  4B3M H;  2JEA I;  3AEV B;  2JVZ A;  5FLX W;  1S20 A;  4DUZ H;  3QD7 X;  4DR1 H;  2YQR A;  1VIG A;  1IBL H;  4JYA H;  1X0A A;  2CTK A;  2PY9 A;  2FMR A;  4DUY H;  1VIH A;  1WTJ A;  1EC6 A;  3GR5 A;  2OPV A;  4AIM A;  1TUA A;  3FAU A;  2ANN A;  4IFD G;  1AN7 A;  1XNR H;  2BL5 A;  3VKE A;  5JEA G;  4B3T H;  2HHH H;  2BA0 A;  4BA1 I;  2E5L H;  2CWH A;  3UOE A;  2MJH A;  1IBM H;  1X4M A;  4X66 H;  4JI1 H;  4DR6 H;  1NXU A;  4X65 H;  1I94 H;  1Z2I A;  2G8Y A;  3L7Z C;  4X62 H;  3SB1 A;  2LTL A;  3T1H H;  4B3R H;  4B3S H;  2A1S A;  4JI4 H;  2O4C A;  2VQE H;  4K0K H;  4OO1 G;  2FPH X;  1J4W A;  1DT4 A;  4H8A A;  4NZT M;  4PDB A;  1V8C A;  4DV6 H;  1N36 H;  2LF0 A;  2UUA H;  5DT9 A;  2UXD H;  4JI2 H;  1ZZK A;  3J81 W;  1PQX A;  4DR3 H;  2NN6 G;  2HH3 A;  2CWF A;  1XMO H;  1WHR A;  1ZTG A;  4DR4 H;  5LL6 b;  3NCV A;  2FFM A;  3J7A K;  2E3U A;  1V9N A;  1S03 G;  3GKU A;  3OSS D;  1FJG H;  3J80 W;  4NXM H;  2JA9 A;  4WAL A;  1XNQ H;  4JI6 H;  1J5E H;  1X4N A;  3T1Y H;  2CPM A;  4FJU A;  4QMF B;  4OX9 H;  2VKC A;  3I0P A;  4JI8 H;  4OCH A;  4DV4 H;  3GAB A;  2QND A;  4BA2 I;  4JVY A;  2ZQE A;  4DV7 H;  2Y3M A;  2CPQ A;  1DTJ A;  3OET A;  5BR8 H;  5A2Q W;  4LF9 H;  4DV5 H;  4LF5 H;  5C0X G;  1HNW H;  1ODH A;  3V69 A;  2F4V H;  1X9Z A;  5K36 G;  1N33 H;  4LF6 H;  1MSZ A;  2OPU A;  2DGR A; 
#chains in the Genus database with same CATH homology
 4FJU A;  1VBI A;  1V9N A;  1X0A A;  1Z2I A;  2G8Y A;  3I0P A;  2CWH A;  4FJS A;  3UOE A;  2CWF A;  1WTJ A;  2X06 A;  1XRH A;  1S20 A;  1NXU A;  4H8A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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