2ANRA

Crystal structure (ii) of nova-1 kh1/kh2 domain tandem with 25nt rna hairpin
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
176
structure length
155
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPQNPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPLQNRVVTVSGEPEQNRKAVELIIQKIQEDPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Rna-binding protein/rna
molecule keywords 5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP
total genus 43
structure length 155
sequence length 176
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2anrA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2anrA02
2JEBI 1ZZIA 4WALA 2JVZA 2BL5A 2PQUA 3L7ZC 2JE6I 1WE8A 3AEVB 1ZZKA 4JVHA 1J4WA 2OPUA 2CPQA 2HH3A 3U1KA 2QNDA 1VIHA 2CTEA 2JZXA 5C0XG 2HH2A 3V69A 1ZTGA 1KHMA 1X4MA 2CTJA 2YQRA 2CTLA 2CTFA 2OPVA 3VKEA 1ZZJA 2MJHA 4QMFB 4AIMA 2ANNA 2CTKA 2P2RA 2CTMA 2NN6G 2ANRA 2JEAI 4LIJA 1X4NA 5K36G 1VIGA 1DTJA 1J5KA 2DGRA 1K1GA 4AM3A 4B8TA 4OO1G 1EC6A 4NBQA 2PY9A 1DT4A 4BA1I 5JEAG 4BA2I 4JVYA 2JA9A 1WVNA 1TUAA 2BA0A 2FMRA 2AXYA 2E3UA 4WANA 4IFDG 2Z0SA
chains in the Genus database with same CATH superfamily
2FFMA 2JEBI 4E9JA 4DV4H 1ZZIA 1XMOH 2PQUA 1N32H 2M8WA 2HHHH 4NZTM 1S03G 1XNRH 4JVHA 3GABA 2CWFA 4LFBH 4JI0H 4DV7H 5LMUH 3KDGA 4EC5A 4NZRM 2CTJA 3VKEA 1ZZJA 4JI3H 4JI4H 2MJHA 2ANNA 2VQFH 4AQYH 2E5LH 2P2RA 5LMNH 2JEAI 1IBKH 4JI5H 1DTJA 1VIGA 4LF8H 2DGRA 1K1GA 4OX9H 3GKUA 4B8TA 4AM3A 4OO1G 1EC6A 5FLXW 1MSZA 2LRRA 4NXNH 1DT4A 2UXCH 1VBIA 2X06A 5BR8H 1WVNA 1TUAA 4FJSA 5A2QW 4DV2H 2QNDA 1PQXA 4JI2H 3KDKA 1XMQH 1N34H 2JVZA 2BL5A 4X66H 2JE6I 2VQEH 1I94H 1WE8A 1Z2IA 5LL6b 1J4WA 2CPMA 2LTMA 4YHHH 2G8YA 2PT7G 4B8CD 3J80W 1SEIA 1IBLH 3U1KA 2ZQEA 1VIHA 2CTEA 1ODHA 4LF6H 2UXDH 4LFCH 3EZJA 1HR0H 2CTMA 2NN6G 4B3SH 1HNZH 3OETA 4DUYH 4GKKH 4B3RH 3RF2A 3QD7X 2VKCA 4NBQA 3SB1A 1S20A 3JAMW 3OTOH 1IBMH 4DR3H 2PY9A 4DR6H 1F0XA 3OSSD 2JA9A 2BA0A 2AXYA 2E3UA 2Y3MA 1NXUA 4LF7H 4IFDG 3FAUA 2K1HA 4K0KH 4WALA 4JI7H 4X64H 2UUCH 1X9ZA 2F4VH 4LF4H 2OPUA 4DV5H 2CPQA 5IT9W 2HH3A 2D9IA 5C0XG 3T1YH 2JZXA 4DUZH 2HH2A 3V69A 1ZTGA 1V8CA 1KHMA 2YQRA 2M6QA 2CTFA 2OPVA 4H8AA 2UU9H 1HNWH 3I0PA 3UOEA 4LFAH 1N36H 4X62H 2ANRA 1FKAH 2UUBH 2LF0A 1X4NA 4JYAH 4OCHA 4KHPH 4OD6A 2A1SA 4DR7H 4LF5H 4NXMH 1XRHA 4BA1I 4G08A 5JEAG 4JI6H 4X65H 4WANA 2FMRA 3AEVB 3J81W 4DR2H 4PDBA 1FJGH 1J5EH 1HNXH 3J7AK 2O4CA 1WHRA 1UG8A 3L7ZC 4YY3H 1X0AA 3T1HH 1ZZKA 4GKJH 2UUAH 4DV1H 3GR5A 4DR5H 4FJUA 4DV6H 4B3TH 1I6UA 4JI8H 4LF9H 3NCVA 1N33H 1X4MA 4DV0H 4JVYA 2CTLA 4JI1H 4DR1H 2UXBH 1WTJA 4QMFB 4AIMA 2CTKA 5DT9A 5K36G 4LIJA 2LTLA 1J5KA 2CWHA 2ZM6H 5IWAH 1AN7A 2FPHX 4DR4H 1V9NA 4BA2I 1XNQH 4JV5H 4B3MH 4DV3H 2Z0SA
chains in the Genus database with same CATH topology
2JEBI 1ZZIA 4WALA 2JVZA 2BL5A 2PQUA 3L7ZC 2JE6I 1WE8A 3AEVB 1ZZKA 4JVHA 1J4WA 2OPUA 2CPQA 2HH3A 3U1KA 2QNDA 1VIHA 2CTEA 2JZXA 5C0XG 2HH2A 3V69A 1ZTGA 1KHMA 1X4MA 2CTJA 2YQRA 2CTLA 2CTFA 2OPVA 3VKEA 1ZZJA 2MJHA 4QMFB 4AIMA 2ANNA 2CTKA 2P2RA 2CTMA 2NN6G 2ANRA 2JEAI 4LIJA 1X4NA 5K36G 1VIGA 1DTJA 1J5KA 2DGRA 1K1GA 4AM3A 4B8TA 4OO1G 1EC6A 4NBQA 2PY9A 1DT4A 4BA1I 5JEAG 4BA2I 4JVYA 2JA9A 1WVNA 1TUAA 2BA0A 2FMRA 2AXYA 2E3UA 4WANA 4IFDG 2Z0SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JEB I;  1ZZI A;  4WAL A;  2JVZ A;  2BL5 A;  2PQU A;  3L7Z C;  2JE6 I;  1WE8 A;  3AEV B;  1ZZK A;  4JVH A;  1J4W A;  2OPU A;  2CPQ A;  2HH3 A;  3U1K A;  2QND A;  1VIH A;  2CTE A;  2JZX A;  5C0X G;  2HH2 A;  3V69 A;  1ZTG A;  1KHM A;  1X4M A;  2CTJ A;  2YQR A;  2CTL A;  2CTF A;  2OPV A;  3VKE A;  1ZZJ A;  2MJH A;  4QMF B;  4AIM A;  2ANN A;  2CTK A;  2P2R A;  2CTM A;  2NN6 G;  2ANR A;  2JEA I;  4LIJ A;  1X4N A;  5K36 G;  1VIG A;  1DTJ A;  1J5K A;  2DGR A;  1K1G A;  4AM3 A;  4B8T A;  4OO1 G;  1EC6 A;  4NBQ A;  2PY9 A;  1DT4 A;  4BA1 I;  5JEA G;  4BA2 I;  4JVY A;  2JA9 A;  1WVN A;  1TUA A;  2BA0 A;  2FMR A;  2AXY A;  2E3U A;  4WAN A;  4IFD G;  2Z0S A; 
#chains in the Genus database with same CATH topology
 2FFM A;  2JEB I;  4E9J A;  4DV4 H;  1ZZI A;  1XMO H;  2PQU A;  1N32 H;  2M8W A;  2HHH H;  4NZT M;  1S03 G;  1XNR H;  4JVH A;  3GAB A;  2CWF A;  4LFB H;  4JI0 H;  4DV7 H;  5LMU H;  3KDG A;  4EC5 A;  4NZR M;  2CTJ A;  3VKE A;  1ZZJ A;  4JI3 H;  4JI4 H;  2MJH A;  2ANN A;  2VQF H;  4AQY H;  2E5L H;  2P2R A;  5LMN H;  2JEA I;  1IBK H;  4JI5 H;  1DTJ A;  1VIG A;  4LF8 H;  2DGR A;  1K1G A;  4OX9 H;  3GKU A;  4B8T A;  4AM3 A;  4OO1 G;  1EC6 A;  5FLX W;  1MSZ A;  2LRR A;  4NXN H;  1DT4 A;  2UXC H;  1VBI A;  2X06 A;  5BR8 H;  1WVN A;  1TUA A;  4FJS A;  5A2Q W;  4DV2 H;  2QND A;  1PQX A;  4JI2 H;  3KDK A;  1XMQ H;  1N34 H;  2JVZ A;  2BL5 A;  4X66 H;  2JE6 I;  2VQE H;  1I94 H;  1WE8 A;  1Z2I A;  5LL6 b;  1J4W A;  2CPM A;  2LTM A;  4YHH H;  2G8Y A;  2PT7 G;  4B8C D;  3J80 W;  1SEI A;  1IBL H;  3U1K A;  2ZQE A;  1VIH A;  2CTE A;  1ODH A;  4LF6 H;  2UXD H;  4LFC H;  3EZJ A;  1HR0 H;  2CTM A;  2NN6 G;  4B3S H;  1HNZ H;  3OET A;  4DUY H;  4GKK H;  4B3R H;  3RF2 A;  3QD7 X;  2VKC A;  4NBQ A;  3SB1 A;  1S20 A;  3JAM W;  3OTO H;  1IBM H;  4DR3 H;  2PY9 A;  4DR6 H;  1F0X A;  3OSS D;  2JA9 A;  2BA0 A;  2AXY A;  2E3U A;  2Y3M A;  1NXU A;  4LF7 H;  4IFD G;  3FAU A;  2K1H A;  4K0K H;  4WAL A;  4JI7 H;  4X64 H;  2UUC H;  1X9Z A;  2F4V H;  4LF4 H;  2OPU A;  4DV5 H;  2CPQ A;  5IT9 W;  2HH3 A;  2D9I A;  5C0X G;  3T1Y H;  2JZX A;  4DUZ H;  2HH2 A;  3V69 A;  1ZTG A;  1V8C A;  1KHM A;  2YQR A;  2M6Q A;  2CTF A;  2OPV A;  4H8A A;  2UU9 H;  1HNW H;  3I0P A;  3UOE A;  4LFA H;  1N36 H;  4X62 H;  2ANR A;  1FKA H;  2UUB H;  2LF0 A;  1X4N A;  4JYA H;  4OCH A;  4KHP H;  4OD6 A;  2A1S A;  4DR7 H;  4LF5 H;  4NXM H;  1XRH A;  4BA1 I;  4G08 A;  5JEA G;  4JI6 H;  4X65 H;  4WAN A;  2FMR A;  3AEV B;  3J81 W;  4DR2 H;  4PDB A;  1FJG H;  1J5E H;  1HNX H;  3J7A K;  2O4C A;  1WHR A;  1UG8 A;  3L7Z C;  4YY3 H;  1X0A A;  3T1H H;  1ZZK A;  4GKJ H;  2UUA H;  4DV1 H;  3GR5 A;  4DR5 H;  4FJU A;  4DV6 H;  4B3T H;  1I6U A;  4JI8 H;  4LF9 H;  3NCV A;  1N33 H;  1X4M A;  4DV0 H;  4JVY A;  2CTL A;  4JI1 H;  4DR1 H;  2UXB H;  1WTJ A;  4QMF B;  4AIM A;  2CTK A;  5DT9 A;  5K36 G;  4LIJ A;  2LTL A;  1J5K A;  2CWH A;  2ZM6 H;  5IWA H;  1AN7 A;  2FPH X;  4DR4 H;  1V9N A;  4BA2 I;  1XNQ H;  4JV5 H;  4B3M H;  4DV3 H;  2Z0S A; 
#chains in the Genus database with same CATH homology
 2JEB I;  1ZZI A;  4WAL A;  2JVZ A;  2BL5 A;  2PQU A;  3L7Z C;  2JE6 I;  1WE8 A;  3AEV B;  1ZZK A;  4JVH A;  1J4W A;  2OPU A;  2CPQ A;  2HH3 A;  3U1K A;  2QND A;  1VIH A;  2CTE A;  2JZX A;  5C0X G;  2HH2 A;  3V69 A;  1ZTG A;  1KHM A;  1X4M A;  2CTJ A;  2YQR A;  2CTL A;  2CTF A;  2OPV A;  3VKE A;  1ZZJ A;  2MJH A;  4QMF B;  4AIM A;  2ANN A;  2CTK A;  2P2R A;  2CTM A;  2NN6 G;  2ANR A;  2JEA I;  4LIJ A;  1X4N A;  5K36 G;  1VIG A;  1DTJ A;  1J5K A;  2DGR A;  1K1G A;  4AM3 A;  4B8T A;  4OO1 G;  1EC6 A;  4NBQ A;  2PY9 A;  1DT4 A;  4BA1 I;  5JEA G;  4BA2 I;  4JVY A;  2JA9 A;  1WVN A;  1TUA A;  2BA0 A;  2FMR A;  2AXY A;  2E3U A;  4WAN A;  4IFD G;  2Z0S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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