2ANRA

Crystal structure (ii) of nova-1 kh1/kh2 domain tandem with 25nt rna hairpin
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
176
structure length
155
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPQNPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPLQNRVVTVSGEPEQNRKAVELIIQKIQEDPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP
publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Rna-binding protein/rna
total genus 43
structure length 155
sequence length 176
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2anrA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2anrA02
2JEBI 2CTFA 2MJHA 2ANRA 2JEAI 4JVYA 1X4NA 2CPQA 4AM3A 1EC6A 2CTEA 1X4MA 2CTLA 2HH2A 1J5KA 2JZXA 4WANA 3U1KA 4IFDG 1ZZJA 2QNDA 1TUAA 2NN6G 4LIJA 2CTMA 3V69A 2HH3A 2PY9A 1J4WA 4OO1G 1KHMA 2OPVA 1WE8A 2E3UA 2ANNA 2P2RA 1VIGA 5C0XG 5JEAG 1ZZIA 2JE6I 1ZTGA 4AIMA 1ZZKA 3VKEA 1DT4A 2FMRA 2CTJA 4BA2I 3L7ZC 4BA1I 5K36G 2DGRA 4WALA 2BL5A 1WVNA 4B8TA 2PQUA 2Z0SA 1DTJA 2CTKA 1K1GA 2BA0A 2AXYA 2JVZA 1VIHA 4JVHA 2OPUA 2YQRA 2JA9A 4QMFB 4NBQA 3AEVB
chains in the Genus database with same CATH superfamily
2JEBI 2JEAI 4OX9H 2CPQA 4AM3A 4JYAH 2LTLA 3JAMW 1N34H 1X4MA 2HH2A 4DR6H 4WANA 4B3RH 4IFDG 1FJGH 1ZZJA 2UUCH 1TUAA 4DV5H 1SEIA 2HH3A 3GKUA 2M6QA 2CPMA 2M8WA 4B3MH 1XNQH 1XNRH 1WE8A 4G08A 2FPHX 2VQFH 2A1SA 1HR0H 2VQEH 2LF0A 3UOEA 5BR8H 3VKEA 3GABA 4OD6A 4NXNH 2DGRA 2PQUA 2D9IA 4LF7H 1DTJA 2CTKA 1IBKH 3J80W 4DV4H 2AXYA 4GKKH 1VIHA 4NXMH 2YQRA 1HNWH 2X06A 1IBMH 1I94H 4NZTM 4EC5A 2CTFA 2FFMA 2MJHA 2G8YA 3OSSD 4DV0H 1FKAH 2ZM6H 4JI5H 4B8CD 4LF8H 4NZRM 1S03G 4DV2H 4LF6H 2LRRA 2VKCA 1UG8A 1N32H 1IBLH 4OCHA 2CWHA 3KDGA 2OPVA 4PDBA 2E3UA 2LTMA 4JI2H 3J81W 2P2RA 1VIGA 1V9NA 5JEAG 4JI7H 2JE6I 4FJUA 3FAUA 1ZTGA 4AIMA 1ZZKA 1S20A 3OTOH 1DT4A 5LMNH 5LMUH 4BA2I 5K36G 1WHRA 4BA1I 4JI6H 4LF5H 4B3SH 2BL5A 4JV5H 4DR3H 1F0XA 3NCVA 4QMFB 2UXCH 3GR5A 2PT7G 3T1YH 4DV1H 5IWAH 4JVYA 1EC6A 1XRHA 4H8AA 1J5KA 2CTLA 3QD7X 3RF2A 3EZJA 2JZXA 1ODHA 1I6UA 3I0PA 2QNDA 2Y3MA 4DR2H 1PQXA 1XMOH 2CTMA 2K1HA 4X65H 2PY9A 5DT9A 1J4WA 3OETA 4OO1G 1KHMA 1N36H 4X64H 1ZZIA 5IT9W 1J5EH 4JI4H 2FMRA 3KDKA 2CTJA 4E9JA 2O4CA 3L7ZC 2UU9H 4JI1H 1WVNA 4B8TA 1HNXH 2Z0SA 4YHHH 1K1GA 5LL6b 2HHHH 2JVZA 5FLXW 4FJSA 4LFAH 2OPUA 1XMQH 2JA9A 2UUBH 4LFCH 4NBQA 1AN7A 3AEVB 4JI3H 2F4VH 2ANRA 1X4NA 4DV3H 2E5LH 1WTJA 4LFBH 2CTEA 2ZQEA 4GKJH 4DR7H 4K0KH 4DR5H 1N33H 3U1KA 4JI0H 2NN6G 4LIJA 3V69A 2UXDH 2UXBH 2UUAH 3J7AK 4B3TH 4DR1H 2CWFA 4DV7H 2ANNA 3SB1A 4DR4H 1VBIA 5C0XG 3T1HH 1NXUA 1X0AA 4DUYH 4X62H 4AQYH 4DUZH 4DV6H 1X9ZA 4X66H 4WALA 1V8CA 1Z2IA 4JI8H 2BA0A 4LF4H 4LF9H 4JVHA 1HNZH 5A2QW 4YY3H 4KHPH 1MSZA
chains in the Genus database with same CATH topology
2JEBI 2CTFA 2MJHA 2ANRA 2JEAI 4JVYA 1X4NA 2CPQA 4AM3A 1EC6A 2CTEA 1X4MA 2CTLA 2HH2A 1J5KA 2JZXA 4WANA 3U1KA 4IFDG 1ZZJA 2QNDA 1TUAA 2NN6G 4LIJA 2CTMA 3V69A 2HH3A 2PY9A 1J4WA 4OO1G 1KHMA 2OPVA 1WE8A 2E3UA 2ANNA 2P2RA 1VIGA 5C0XG 5JEAG 1ZZIA 2JE6I 1ZTGA 4AIMA 1ZZKA 3VKEA 1DT4A 2FMRA 2CTJA 4BA2I 3L7ZC 4BA1I 5K36G 2DGRA 4WALA 2BL5A 1WVNA 4B8TA 2PQUA 2Z0SA 1DTJA 2CTKA 1K1GA 2BA0A 2AXYA 2JVZA 1VIHA 4JVHA 2OPUA 2YQRA 2JA9A 4QMFB 4NBQA 3AEVB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JEB I;  2CTF A;  2MJH A;  2ANR A;  2JEA I;  4JVY A;  1X4N A;  2CPQ A;  4AM3 A;  1EC6 A;  2CTE A;  1X4M A;  2CTL A;  2HH2 A;  1J5K A;  2JZX A;  4WAN A;  3U1K A;  4IFD G;  1ZZJ A;  2QND A;  1TUA A;  2NN6 G;  4LIJ A;  2CTM A;  3V69 A;  2HH3 A;  2PY9 A;  1J4W A;  4OO1 G;  1KHM A;  2OPV A;  1WE8 A;  2E3U A;  2ANN A;  2P2R A;  1VIG A;  5C0X G;  5JEA G;  1ZZI A;  2JE6 I;  1ZTG A;  4AIM A;  1ZZK A;  3VKE A;  1DT4 A;  2FMR A;  2CTJ A;  4BA2 I;  3L7Z C;  4BA1 I;  5K36 G;  2DGR A;  4WAL A;  2BL5 A;  1WVN A;  4B8T A;  2PQU A;  2Z0S A;  1DTJ A;  2CTK A;  1K1G A;  2BA0 A;  2AXY A;  2JVZ A;  1VIH A;  4JVH A;  2OPU A;  2YQR A;  2JA9 A;  4QMF B;  4NBQ A;  3AEV B; 
#chains in the Genus database with same CATH topology
 2JEB I;  2JEA I;  4OX9 H;  2CPQ A;  4AM3 A;  4JYA H;  2LTL A;  3JAM W;  1N34 H;  1X4M A;  2HH2 A;  4DR6 H;  4WAN A;  4B3R H;  4IFD G;  1FJG H;  1ZZJ A;  2UUC H;  1TUA A;  4DV5 H;  1SEI A;  2HH3 A;  3GKU A;  2M6Q A;  2CPM A;  2M8W A;  4B3M H;  1XNQ H;  1XNR H;  1WE8 A;  4G08 A;  2FPH X;  2VQF H;  2A1S A;  1HR0 H;  2VQE H;  2LF0 A;  3UOE A;  5BR8 H;  3VKE A;  3GAB A;  4OD6 A;  4NXN H;  2DGR A;  2PQU A;  2D9I A;  4LF7 H;  1DTJ A;  2CTK A;  1IBK H;  3J80 W;  4DV4 H;  2AXY A;  4GKK H;  1VIH A;  4NXM H;  2YQR A;  1HNW H;  2X06 A;  1IBM H;  1I94 H;  4NZT M;  4EC5 A;  2CTF A;  2FFM A;  2MJH A;  2G8Y A;  3OSS D;  4DV0 H;  1FKA H;  2ZM6 H;  4JI5 H;  4B8C D;  4LF8 H;  4NZR M;  1S03 G;  4DV2 H;  4LF6 H;  2LRR A;  2VKC A;  1UG8 A;  1N32 H;  1IBL H;  4OCH A;  2CWH A;  3KDG A;  2OPV A;  4PDB A;  2E3U A;  2LTM A;  4JI2 H;  3J81 W;  2P2R A;  1VIG A;  1V9N A;  5JEA G;  4JI7 H;  2JE6 I;  4FJU A;  3FAU A;  1ZTG A;  4AIM A;  1ZZK A;  1S20 A;  3OTO H;  1DT4 A;  5LMN H;  5LMU H;  4BA2 I;  5K36 G;  1WHR A;  4BA1 I;  4JI6 H;  4LF5 H;  4B3S H;  2BL5 A;  4JV5 H;  4DR3 H;  1F0X A;  3NCV A;  4QMF B;  2UXC H;  3GR5 A;  2PT7 G;  3T1Y H;  4DV1 H;  5IWA H;  4JVY A;  1EC6 A;  1XRH A;  4H8A A;  1J5K A;  2CTL A;  3QD7 X;  3RF2 A;  3EZJ A;  2JZX A;  1ODH A;  1I6U A;  3I0P A;  2QND A;  2Y3M A;  4DR2 H;  1PQX A;  1XMO H;  2CTM A;  2K1H A;  4X65 H;  2PY9 A;  5DT9 A;  1J4W A;  3OET A;  4OO1 G;  1KHM A;  1N36 H;  4X64 H;  1ZZI A;  5IT9 W;  1J5E H;  4JI4 H;  2FMR A;  3KDK A;  2CTJ A;  4E9J A;  2O4C A;  3L7Z C;  2UU9 H;  4JI1 H;  1WVN A;  4B8T A;  1HNX H;  2Z0S A;  4YHH H;  1K1G A;  5LL6 b;  2HHH H;  2JVZ A;  5FLX W;  4FJS A;  4LFA H;  2OPU A;  1XMQ H;  2JA9 A;  2UUB H;  4LFC H;  4NBQ A;  1AN7 A;  3AEV B;  4JI3 H;  2F4V H;  2ANR A;  1X4N A;  4DV3 H;  2E5L H;  1WTJ A;  4LFB H;  2CTE A;  2ZQE A;  4GKJ H;  4DR7 H;  4K0K H;  4DR5 H;  1N33 H;  3U1K A;  4JI0 H;  2NN6 G;  4LIJ A;  3V69 A;  2UXD H;  2UXB H;  2UUA H;  3J7A K;  4B3T H;  4DR1 H;  2CWF A;  4DV7 H;  2ANN A;  3SB1 A;  4DR4 H;  1VBI A;  5C0X G;  3T1H H;  1NXU A;  1X0A A;  4DUY H;  4X62 H;  4AQY H;  4DUZ H;  4DV6 H;  1X9Z A;  4X66 H;  4WAL A;  1V8C A;  1Z2I A;  4JI8 H;  2BA0 A;  4LF4 H;  4LF9 H;  4JVH A;  1HNZ H;  5A2Q W;  4YY3 H;  4KHP H;  1MSZ A; 
#chains in the Genus database with same CATH homology
 2JEB I;  2CTF A;  2MJH A;  2ANR A;  2JEA I;  4JVY A;  1X4N A;  2CPQ A;  4AM3 A;  1EC6 A;  2CTE A;  1X4M A;  2CTL A;  2HH2 A;  1J5K A;  2JZX A;  4WAN A;  3U1K A;  4IFD G;  1ZZJ A;  2QND A;  1TUA A;  2NN6 G;  4LIJ A;  2CTM A;  3V69 A;  2HH3 A;  2PY9 A;  1J4W A;  4OO1 G;  1KHM A;  2OPV A;  1WE8 A;  2E3U A;  2ANN A;  2P2R A;  1VIG A;  5C0X G;  5JEA G;  1ZZI A;  2JE6 I;  1ZTG A;  4AIM A;  1ZZK A;  3VKE A;  1DT4 A;  2FMR A;  2CTJ A;  4BA2 I;  3L7Z C;  4BA1 I;  5K36 G;  2DGR A;  4WAL A;  2BL5 A;  1WVN A;  4B8T A;  2PQU A;  2Z0S A;  1DTJ A;  2CTK A;  1K1G A;  2BA0 A;  2AXY A;  2JVZ A;  1VIH A;  4JVH A;  2OPU A;  2YQR A;  2JA9 A;  4QMF B;  4NBQ A;  3AEV B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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