2ANRA

Crystal structure (ii) of nova-1 kh1/kh2 domain tandem with 25nt rna hairpin
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
176
structure length
155
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPQNPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPLQNRVVTVSGEPEQNRKAVELIIQKIQEDPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Rna-binding protein/rna
molecule keywords 5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP
publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
source organism Homo sapiens
total genus 43
structure length 155
sequence length 176
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2anrA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2anrA02
2YQRA 2Z0SA 1X4MA 4BA1I 1TUAA 2JE6I 2CPQA 2JVZA 4QMFB 2PY9A 1WVNA 2CTEA 4NBQA 2MJHA 2DGRA 4LIJA 2PQUA 2CTJA 1DTJA 1J5KA 2ANNA 2JEBI 3VKEA 4B8TA 2E3UA 2HH2A 5JEAG 2AXYA 1J4WA 2JEAI 2P2RA 2BL5A 3U1KA 2CTMA 1ZZJA 1KHMA 1VIGA 2JA9A 2OPVA 3L7ZC 1VIHA 3V69A 2BA0A 4JVHA 5C0XG 1ZTGA 4IFDG 4BA2I 1DT4A 1EC6A 1K1GA 4AIMA 4JVYA 2CTKA 2FMRA 4WALA 1X4NA 4OO1G 2ANRA 2OPUA 4WANA 1ZZKA 2JZXA 1WE8A 2CTLA 2NN6G 2QNDA 1ZZIA 5K36G 2HH3A 3AEVB 4AM3A 2CTFA
chains in the Genus database with same CATH superfamily
1AN7A 4BA1I 4JI4H 3OSSD 2JE6I 4X64H 3T1HH 1WVNA 2PT7G 4DV5H 4X66H 1IBLH 5LMNH 1ODHA 2ANNA 3VKEA 1I94H 4GKJH 1N34H 1F0XA 4LF8H 4K0KH 2UXDH 2HH2A 4DV6H 2AXYA 4JI6H 1SEIA 1N33H 2JEAI 1HNZH 3KDKA 3U1KA 1VIGA 4B3MH 3UOEA 3L7ZC 1WTJA 4LFBH 4JVHA 2UXCH 1IBKH 1IBMH 4LFAH 3GABA 1N32H 4JVYA 2CTKA 1Z2IA 2FMRA 3OTOH 4AQYH 2ANRA 1WHRA 2OPUA 3I0PA 2FFMA 5BR8H 2CWHA 4JI5H 1ZZIA 2LTLA 4B3SH 5K36G 3AEVB 3QD7X 4DV1H 4JI0H 3OETA 2YQRA 1X4MA 1PQXA 1NXUA 5DT9A 4QMFB 3J81W 2PY9A 1I6UA 4NBQA 1XNRH 4FJSA 1N36H 4DR2H 3J7AK 4B8TA 3SB1A 2E3UA 5JEAG 2HHHH 2M6QA 4DUYH 4DV4H 4DR4H 2JA9A 3RF2A 4JV5H 2CWFA 5C0XG 4OX9H 2K1HA 1ZTGA 4BA2I 1DT4A 3EZJA 4DR5H 2F4VH 2E5LH 1HNWH 1X9ZA 4OO1G 4EC5A 2ZQEA 2UUBH 4LF7H 1VBIA 4OCHA 2M8WA 2LF0A 2UU9H 4AM3A 2UUAH 4LF5H 5LL6b 1TUAA 4B8CD 4DR3H 2O4CA 2JVZA 1FKAH 3T1YH 2VKCA 2CTEA 1V9NA 2ZM6H 2DGRA 4LIJA 2MJHA 2UXBH 4LF9H 2UUCH 2CPMA 4B3RH 1UG8A 4X62H 4KHPH 1J4WA 4NXNH 5A2QW 4NZTM 2BL5A 1ZZJA 4B3TH 1KHMA 5FLXW 3V69A 2OPVA 2X06A 1VIHA 4DR1H 2BA0A 4E9JA 4DV7H 4IFDG 4FJUA 4JI1H 1EC6A 3GR5A 1J5EH 1X4NA 3J80W 4WANA 4OD6A 1FJGH 5IT9W 2JZXA 1WE8A 2CTLA 2QNDA 5LMUH 4X65H 4DUZH 1S03G 1XMOH 4G08A 2Z0SA 4JI2H 1XNQH 4PDBA 3KDGA 2VQFH 2CPQA 3GKUA 4LF4H 2VQEH 2PQUA 2CTJA 1DTJA 1J5KA 3JAMW 4DV0H 2LRRA 1HR0H 4NXMH 2JEBI 5IWAH 4DR7H 3NCVA 4GKKH 2G8YA 4DV3H 4DV2H 1V8CA 2A1SA 2P2RA 4H8AA 4LF6H 4JI8H 1XRHA 2CTMA 4YHHH 1XMQH 4NZRM 4JI7H 4DR6H 1S20A 4JYAH 3FAUA 4JI3H 1K1GA 4AIMA 4WALA 1HNXH 4YY3H 1ZZKA 4LFCH 2FPHX 2LTMA 2NN6G 1MSZA 1X0AA 2Y3MA 2D9IA 2HH3A 2CTFA
chains in the Genus database with same CATH topology
2YQRA 2Z0SA 1X4MA 4BA1I 1TUAA 2JE6I 2CPQA 2JVZA 4QMFB 2PY9A 1WVNA 2CTEA 4NBQA 2MJHA 2DGRA 4LIJA 2PQUA 2CTJA 1DTJA 1J5KA 2ANNA 2JEBI 3VKEA 4B8TA 2E3UA 2HH2A 5JEAG 2AXYA 1J4WA 2JEAI 2P2RA 2BL5A 3U1KA 2CTMA 1ZZJA 1KHMA 1VIGA 2JA9A 2OPVA 3L7ZC 1VIHA 3V69A 2BA0A 4JVHA 5C0XG 1ZTGA 4IFDG 4BA2I 1DT4A 1EC6A 1K1GA 4AIMA 4JVYA 2CTKA 2FMRA 4WALA 1X4NA 4OO1G 2ANRA 2OPUA 4WANA 1ZZKA 2JZXA 1WE8A 2CTLA 2NN6G 2QNDA 1ZZIA 5K36G 2HH3A 3AEVB 4AM3A 2CTFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YQR A;  2Z0S A;  1X4M A;  4BA1 I;  1TUA A;  2JE6 I;  2CPQ A;  2JVZ A;  4QMF B;  2PY9 A;  1WVN A;  2CTE A;  4NBQ A;  2MJH A;  2DGR A;  4LIJ A;  2PQU A;  2CTJ A;  1DTJ A;  1J5K A;  2ANN A;  2JEB I;  3VKE A;  4B8T A;  2E3U A;  2HH2 A;  5JEA G;  2AXY A;  1J4W A;  2JEA I;  2P2R A;  2BL5 A;  3U1K A;  2CTM A;  1ZZJ A;  1KHM A;  1VIG A;  2JA9 A;  2OPV A;  3L7Z C;  1VIH A;  3V69 A;  2BA0 A;  4JVH A;  5C0X G;  1ZTG A;  4IFD G;  4BA2 I;  1DT4 A;  1EC6 A;  1K1G A;  4AIM A;  4JVY A;  2CTK A;  2FMR A;  4WAL A;  1X4N A;  4OO1 G;  2ANR A;  2OPU A;  4WAN A;  1ZZK A;  2JZX A;  1WE8 A;  2CTL A;  2NN6 G;  2QND A;  1ZZI A;  5K36 G;  2HH3 A;  3AEV B;  4AM3 A;  2CTF A; 
#chains in the Genus database with same CATH topology
 1AN7 A;  4BA1 I;  4JI4 H;  3OSS D;  2JE6 I;  4X64 H;  3T1H H;  1WVN A;  2PT7 G;  4DV5 H;  4X66 H;  1IBL H;  5LMN H;  1ODH A;  2ANN A;  3VKE A;  1I94 H;  4GKJ H;  1N34 H;  1F0X A;  4LF8 H;  4K0K H;  2UXD H;  2HH2 A;  4DV6 H;  2AXY A;  4JI6 H;  1SEI A;  1N33 H;  2JEA I;  1HNZ H;  3KDK A;  3U1K A;  1VIG A;  4B3M H;  3UOE A;  3L7Z C;  1WTJ A;  4LFB H;  4JVH A;  2UXC H;  1IBK H;  1IBM H;  4LFA H;  3GAB A;  1N32 H;  4JVY A;  2CTK A;  1Z2I A;  2FMR A;  3OTO H;  4AQY H;  2ANR A;  1WHR A;  2OPU A;  3I0P A;  2FFM A;  5BR8 H;  2CWH A;  4JI5 H;  1ZZI A;  2LTL A;  4B3S H;  5K36 G;  3AEV B;  3QD7 X;  4DV1 H;  4JI0 H;  3OET A;  2YQR A;  1X4M A;  1PQX A;  1NXU A;  5DT9 A;  4QMF B;  3J81 W;  2PY9 A;  1I6U A;  4NBQ A;  1XNR H;  4FJS A;  1N36 H;  4DR2 H;  3J7A K;  4B8T A;  3SB1 A;  2E3U A;  5JEA G;  2HHH H;  2M6Q A;  4DUY H;  4DV4 H;  4DR4 H;  2JA9 A;  3RF2 A;  4JV5 H;  2CWF A;  5C0X G;  4OX9 H;  2K1H A;  1ZTG A;  4BA2 I;  1DT4 A;  3EZJ A;  4DR5 H;  2F4V H;  2E5L H;  1HNW H;  1X9Z A;  4OO1 G;  4EC5 A;  2ZQE A;  2UUB H;  4LF7 H;  1VBI A;  4OCH A;  2M8W A;  2LF0 A;  2UU9 H;  4AM3 A;  2UUA H;  4LF5 H;  5LL6 b;  1TUA A;  4B8C D;  4DR3 H;  2O4C A;  2JVZ A;  1FKA H;  3T1Y H;  2VKC A;  2CTE A;  1V9N A;  2ZM6 H;  2DGR A;  4LIJ A;  2MJH A;  2UXB H;  4LF9 H;  2UUC H;  2CPM A;  4B3R H;  1UG8 A;  4X62 H;  4KHP H;  1J4W A;  4NXN H;  5A2Q W;  4NZT M;  2BL5 A;  1ZZJ A;  4B3T H;  1KHM A;  5FLX W;  3V69 A;  2OPV A;  2X06 A;  1VIH A;  4DR1 H;  2BA0 A;  4E9J A;  4DV7 H;  4IFD G;  4FJU A;  4JI1 H;  1EC6 A;  3GR5 A;  1J5E H;  1X4N A;  3J80 W;  4WAN A;  4OD6 A;  1FJG H;  5IT9 W;  2JZX A;  1WE8 A;  2CTL A;  2QND A;  5LMU H;  4X65 H;  4DUZ H;  1S03 G;  1XMO H;  4G08 A;  2Z0S A;  4JI2 H;  1XNQ H;  4PDB A;  3KDG A;  2VQF H;  2CPQ A;  3GKU A;  4LF4 H;  2VQE H;  2PQU A;  2CTJ A;  1DTJ A;  1J5K A;  3JAM W;  4DV0 H;  2LRR A;  1HR0 H;  4NXM H;  2JEB I;  5IWA H;  4DR7 H;  3NCV A;  4GKK H;  2G8Y A;  4DV3 H;  4DV2 H;  1V8C A;  2A1S A;  2P2R A;  4H8A A;  4LF6 H;  4JI8 H;  1XRH A;  2CTM A;  4YHH H;  1XMQ H;  4NZR M;  4JI7 H;  4DR6 H;  1S20 A;  4JYA H;  3FAU A;  4JI3 H;  1K1G A;  4AIM A;  4WAL A;  1HNX H;  4YY3 H;  1ZZK A;  4LFC H;  2FPH X;  2LTM A;  2NN6 G;  1MSZ A;  1X0A A;  2Y3M A;  2D9I A;  2HH3 A;  2CTF A; 
#chains in the Genus database with same CATH homology
 2YQR A;  2Z0S A;  1X4M A;  4BA1 I;  1TUA A;  2JE6 I;  2CPQ A;  2JVZ A;  4QMF B;  2PY9 A;  1WVN A;  2CTE A;  4NBQ A;  2MJH A;  2DGR A;  4LIJ A;  2PQU A;  2CTJ A;  1DTJ A;  1J5K A;  2ANN A;  2JEB I;  3VKE A;  4B8T A;  2E3U A;  2HH2 A;  5JEA G;  2AXY A;  1J4W A;  2JEA I;  2P2R A;  2BL5 A;  3U1K A;  2CTM A;  1ZZJ A;  1KHM A;  1VIG A;  2JA9 A;  2OPV A;  3L7Z C;  1VIH A;  3V69 A;  2BA0 A;  4JVH A;  5C0X G;  1ZTG A;  4IFD G;  4BA2 I;  1DT4 A;  1EC6 A;  1K1G A;  4AIM A;  4JVY A;  2CTK A;  2FMR A;  4WAL A;  1X4N A;  4OO1 G;  2ANR A;  2OPU A;  4WAN A;  1ZZK A;  2JZX A;  1WE8 A;  2CTL A;  2NN6 G;  2QND A;  1ZZI A;  5K36 G;  2HH3 A;  3AEV B;  4AM3 A;  2CTF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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