1V9NA

Structure of malate dehydrogenase from pyrococcus horikoshii ot3
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
360
structure length
348
Chain Sequence
MFEKGYVDENYIRVPKDRLFSFIVRVLTKLGVPEEDAKIVADNLVMADLRGVESHGVQRLKRYVDGIISGGVNLHPKIRVIREGPSYALIDGDEGLGQVVGYRSMKLAIKKAKDTGIGIVIARNSNHYGIAGYYALMAAEEGMIGISMTNSRPLVAPTGGIERILGTNPIALAAPTKDKPFLLDMATSVVPIGKLEWAINREGNITTKVEEVFNGGALLPLGGFGELLGGHKGYGLSLMVDILSGILSGGTWSKYVKNTSEKGSNVCHFFMVIDIEHFIPLEEFKEKISQMIEEIKSSRKHPEFERIWIHGEKGFLTMETRLKLGIPIYRKVLEELNEIAKRVGVEGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Pyrococcus horikoshii
publication title Structure of Malate Dehydrogenase from Pyrococcus horikoshii OT3
rcsb
molecule keywords Malate dehydrogenase
total genus 99
structure length 348
sequence length 360
ec nomenclature ec 1.1.1.37: Malate dehydrogenase.
pdb deposition date 2004-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1v9nA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1v9nA02
2X06A 1NXUA 2G8YA 3I0PA 2CWFA 1V9NA 4FJUA 1VBIA 4H8AA 1XRHA 1S20A 1X0AA 3UOEA 1WTJA 4FJSA 1Z2IA 2CWHA
chains in the Genus database with same CATH superfamily
4DV7H 1PQXA 5LMUH 4DR4H 3I0PA 2CWFA 5FLXW 4B3TH 4G08A 4DV4H 2LRRA 1IBKH 2ZQEA 2X06A 4DR1H 2JEAI 3OSSD 2JVZA 2HHHH 1V9NA 2HH2A 4H8AA 2PT7G 1ODHA 2OPVA 1HNWH 2CTKA 1MSZA 4LF4H 4QMFB 3OTOH 1S03G 1FKAH 2G8YA 1X9ZA 2HH3A 1ZTGA 1ZZKA 2OPUA 4DV1H 4JI0H 4OX9H 4NBQA 4WALA 3UOEA 2QNDA 1WTJA 2VKCA 2P2RA 2AXYA 1I94H 5IWAH 3JAMW 4JI3H 4NXMH 3U1KA 4DR6H 4YY3H 4K0KH 1N34H 1HNXH 3J7AK 1N32H 1N36H 4BA2I 3GR5A 3NCVA 2LTLA 4OD6A 2ZM6H 3T1YH 1TUAA 1VBIA 2FPHX 4E9JA 2PQUA 4NZRM 4LFAH 2M8WA 4JI2H 4DR7H 4DUYH 4X64H 2VQEH 4X66H 4AM3A 4LF8H 2YQRA 1J5KA 4LF6H 4EC5A 1N33H 2ANRA 1ZZJA 4NXNH 4GKJH 3L7ZC 2JZXA 4JVYA 1DTJA 2M6QA 1XMOH 3EZJA 1XMQH 1V8CA 4DV6H 4B3RH 4JI7H 1FJGH 1I6UA 1IBLH 2ANNA 2E3UA 3J81W 4JV5H 4JYAH 4X62H 3AEVB 4JI4H 5BR8H 1X0AA 5C0XG 1ZZIA 3V69A 4JI8H 5JEAG 1NXUA 4X65H 1VIGA 2FFMA 4PDBA 2UXCH 4LFBH 3QD7X 2A1SA 1EC6A 4DR5H 5IT9W 3GABA 1X4NA 4OCHA 1K1GA 3T1HH 1UG8A 1J4WA 4YHHH 5LMNH 2UUCH 2UUBH 3RF2A 1S20A 1IBMH 4B3SH 1WE8A 2BA0A 4DV5H 4JI1H 2VQFH 4AQYH 1WHRA 4KHPH 2JE6I 1J5EH 2CPQA 2UUAH 1SEIA 4NZTM 4DUZH 2Z0SA 1AN7A 1XRHA 4FJUA 4IFDG 3KDGA 2F4VH 1HNZH 3OETA 4B3MH 4OO1G 2CTEA 2CTMA 4DV0H 5LL6b 4DV3H 4JVHA 4JI5H 1HR0H 2CTLA 2E5LH 1DT4A 4DV2H 3J80W 2UU9H 4DR2H 2PY9A 4B8TA 3KDKA 4LF9H 1XNQH 2NN6G 2CPMA 2Y3MA 4AIMA 2LF0A 4LF5H 4B8CD 4JI6H 1KHMA 3FAUA 1F0XA 2FMRA 2UXDH 3SB1A 1X4MA 4DR3H 4WANA 5K36G 5A2QW 3GKUA 2LTMA 1VIHA 4GKKH 1WVNA 2DGRA 4FJSA 1Z2IA 5DT9A 2BL5A 2D9IA 4BA1I 2K1HA 4LF7H 2JA9A 2O4CA 3VKEA 1XNRH 4LFCH 2CTJA 2JEBI 4LIJA 2MJHA 2CTFA 2UXBH 2CWHA
chains in the Genus database with same CATH topology
2X06A 1NXUA 2G8YA 3I0PA 2CWFA 1V9NA 4FJUA 1VBIA 4H8AA 1XRHA 1S20A 1X0AA 3UOEA 1WTJA 4FJSA 1Z2IA 2CWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X06 A;  1NXU A;  2G8Y A;  3I0P A;  2CWF A;  1V9N A;  4FJU A;  1VBI A;  4H8A A;  1XRH A;  1S20 A;  1X0A A;  3UOE A;  1WTJ A;  4FJS A;  1Z2I A;  2CWH A; 
#chains in the Genus database with same CATH topology
 4DV7 H;  1PQX A;  5LMU H;  4DR4 H;  3I0P A;  2CWF A;  5FLX W;  4B3T H;  4G08 A;  4DV4 H;  2LRR A;  1IBK H;  2ZQE A;  2X06 A;  4DR1 H;  2JEA I;  3OSS D;  2JVZ A;  2HHH H;  1V9N A;  2HH2 A;  4H8A A;  2PT7 G;  1ODH A;  2OPV A;  1HNW H;  2CTK A;  1MSZ A;  4LF4 H;  4QMF B;  3OTO H;  1S03 G;  1FKA H;  2G8Y A;  1X9Z A;  2HH3 A;  1ZTG A;  1ZZK A;  2OPU A;  4DV1 H;  4JI0 H;  4OX9 H;  4NBQ A;  4WAL A;  3UOE A;  2QND A;  1WTJ A;  2VKC A;  2P2R A;  2AXY A;  1I94 H;  5IWA H;  3JAM W;  4JI3 H;  4NXM H;  3U1K A;  4DR6 H;  4YY3 H;  4K0K H;  1N34 H;  1HNX H;  3J7A K;  1N32 H;  1N36 H;  4BA2 I;  3GR5 A;  3NCV A;  2LTL A;  4OD6 A;  2ZM6 H;  3T1Y H;  1TUA A;  1VBI A;  2FPH X;  4E9J A;  2PQU A;  4NZR M;  4LFA H;  2M8W A;  4JI2 H;  4DR7 H;  4DUY H;  4X64 H;  2VQE H;  4X66 H;  4AM3 A;  4LF8 H;  2YQR A;  1J5K A;  4LF6 H;  4EC5 A;  1N33 H;  2ANR A;  1ZZJ A;  4NXN H;  4GKJ H;  3L7Z C;  2JZX A;  4JVY A;  1DTJ A;  2M6Q A;  1XMO H;  3EZJ A;  1XMQ H;  1V8C A;  4DV6 H;  4B3R H;  4JI7 H;  1FJG H;  1I6U A;  1IBL H;  2ANN A;  2E3U A;  3J81 W;  4JV5 H;  4JYA H;  4X62 H;  3AEV B;  4JI4 H;  5BR8 H;  1X0A A;  5C0X G;  1ZZI A;  3V69 A;  4JI8 H;  5JEA G;  1NXU A;  4X65 H;  1VIG A;  2FFM A;  4PDB A;  2UXC H;  4LFB H;  3QD7 X;  2A1S A;  1EC6 A;  4DR5 H;  5IT9 W;  3GAB A;  1X4N A;  4OCH A;  1K1G A;  3T1H H;  1UG8 A;  1J4W A;  4YHH H;  5LMN H;  2UUC H;  2UUB H;  3RF2 A;  1S20 A;  1IBM H;  4B3S H;  1WE8 A;  2BA0 A;  4DV5 H;  4JI1 H;  2VQF H;  4AQY H;  1WHR A;  4KHP H;  2JE6 I;  1J5E H;  2CPQ A;  2UUA H;  1SEI A;  4NZT M;  4DUZ H;  2Z0S A;  1AN7 A;  1XRH A;  4FJU A;  4IFD G;  3KDG A;  2F4V H;  1HNZ H;  3OET A;  4B3M H;  4OO1 G;  2CTE A;  2CTM A;  4DV0 H;  5LL6 b;  4DV3 H;  4JVH A;  4JI5 H;  1HR0 H;  2CTL A;  2E5L H;  1DT4 A;  4DV2 H;  3J80 W;  2UU9 H;  4DR2 H;  2PY9 A;  4B8T A;  3KDK A;  4LF9 H;  1XNQ H;  2NN6 G;  2CPM A;  2Y3M A;  4AIM A;  2LF0 A;  4LF5 H;  4B8C D;  4JI6 H;  1KHM A;  3FAU A;  1F0X A;  2FMR A;  2UXD H;  3SB1 A;  1X4M A;  4DR3 H;  4WAN A;  5K36 G;  5A2Q W;  3GKU A;  2LTM A;  1VIH A;  4GKK H;  1WVN A;  2DGR A;  4FJS A;  1Z2I A;  5DT9 A;  2BL5 A;  2D9I A;  4BA1 I;  2K1H A;  4LF7 H;  2JA9 A;  2O4C A;  3VKE A;  1XNR H;  4LFC H;  2CTJ A;  2JEB I;  4LIJ A;  2MJH A;  2CTF A;  2UXB H;  2CWH A; 
#chains in the Genus database with same CATH homology
 2X06 A;  1NXU A;  2G8Y A;  3I0P A;  2CWF A;  1V9N A;  4FJU A;  1VBI A;  4H8A A;  1XRH A;  1S20 A;  1X0A A;  3UOE A;  1WTJ A;  4FJS A;  1Z2I A;  2CWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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