1X0AA

Crystal structure of type ii malate/lactate dehydrogenase from thermus thermophilus hb8
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
344
structure length
344
Chain Sequence
MRWRADFLSAWAEALLRKAGADEPSAKAVAWALVEADLRGVGSHGLLRLPVYVRRLEAGLVNPSPTLPLEERGPVALLDGEHGFGPRVALKAVEAAQSLARRHGLGAVGVRRSTHFGMAGLYAEKLAREGFVAWVTTNAEPDVVPFGGREKALGTNPLAFAAPAPQGILVADLATSESAMGKVFLAREKGERIPPSWGVDREGSPTDDPHRVYALRPLGGPKGYALALLVEVLSGVLTGAGVAHGIGRMYDEWDRPQDVGHFLLALDPGRFVGKEAFLERMGALWQALKATPPAPGHEEVFLPGELEARRRERALAEGMALPERVVAELKALGERYGVPWRDDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8
rcsb
molecule tags Oxidoreductase
source organism Thermus thermophilus
molecule keywords malate/L-lactate dehydrogenase family protein
total genus 115
structure length 344
sequence length 344
ec nomenclature ec 1.1.1.27: L-lactate dehydrogenase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1x0aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1x0aA02
4FJSA 2G8YA 3I0PA 1XRHA 4FJUA 2CWFA 1S20A 1Z2IA 2CWHA 2X06A 1X0AA 1WTJA 1V9NA 1VBIA 3UOEA 4H8AA 1NXUA
chains in the Genus database with same CATH superfamily
2QNDA 5IWAH 4DR4H 1XRHA 2M6QA 2ZQEA 2DGRA 4B8CD 2M8WA 2UU9H 4NXMH 5IT9W 4B3TH 2JE6I 4E9JA 3KDKA 1X4NA 4JI7H 4DR3H 2CTEA 3RF2A 5K36G 4X64H 1MSZA 2JA9A 3L7ZC 2D9IA 1HNXH 2BL5A 2LTMA 1VIHA 3KDGA 3GABA 3I0PA 1IBKH 4LFBH 4DR5H 4BA2I 2CTLA 2JVZA 2OPVA 4JV5H 2UXDH 2JEBI 4DV0H 4DV4H 4X66H 2UXBH 2PY9A 2CTMA 2LTLA 1V8CA 3JAMW 1V9NA 4NZTM 4DV7H 4K0KH 2Z0SA 1F0XA 4OCHA 4AQYH 1ODHA 4JI5H 1K1GA 3SB1A 2HH3A 3T1YH 1XNQH 2HH2A 4PDBA 2O4CA 2HHHH 3OETA 2JZXA 4LFCH 1XNRH 4EC5A 4DV1H 5DT9A 1S03G 3V69A 1KHMA 4OO1G 2CTFA 1N36H 1S20A 4NXNH 2JEAI 4DUZH 4BA1I 2UXCH 2CTKA 4YHHH 4JI6H 4B3MH 2ZM6H 1FKAH 1IBMH 4DR6H 1HNWH 2BA0A 2YQRA 4WALA 2VQEH 3J81W 1XMQH 4NZRM 1FJGH 1UG8A 4DV3H 2G8YA 4B3RH 1DTJA 5LMUH 4WANA 3J80W 1N32H 2FMRA 4B3SH 4IFDG 2CPMA 4X65H 1I94H 4DR1H 1NXUA 4JI3H 4DV2H 1ZZKA 3FAUA 2NN6G 4LIJA 1XMOH 1N34H 2LF0A 4OX9H 4OD6A 4LFAH 3OTOH 1J4WA 1VIGA 4JI0H 4GKJH 4QMFB 4YY3H 2PQUA 1AN7A 5JEAG 3U1KA 1TUAA 4DUYH 2P2RA 4JI1H 4LF8H 2LRRA 3QD7X 1SEIA 3EZJA 1VBIA 2E5LH 4H8AA 2CTJA 2UUBH 1J5KA 2FFMA 2OPUA 3VKEA 1Z2IA 4AIMA 1ZTGA 4JI2H 2K1HA 2ANRA 2ANNA 1WVNA 1HNZH 3AEVB 2E3UA 1X4MA 4LF6H 4NBQA 4JYAH 2VKCA 2CWFA 2CWHA 2FPHX 3J7AK 3GKUA 4GKKH 4LF7H 2F4VH 4DR2H 2UUAH 4B8TA 1X9ZA 1WHRA 5LL6b 3NCVA 1WE8A 2VQFH 1J5EH 4JI4H 4JI8H 3OSSD 2MJHA 4LF4H 4FJSA 3GR5A 2A1SA 4DV5H 4DR7H 4JVHA 4FJUA 1EC6A 1X0AA 1WTJA 1PQXA 4AM3A 4JVYA 5A2QW 5BR8H 2AXYA 4X62H 4DV6H 4LF9H 4KHPH 1N33H 5LMNH 1DT4A 3T1HH 1ZZJA 3UOEA 1ZZIA 2Y3MA 1IBLH 2PT7G 2UUCH 5C0XG 2X06A 1I6UA 2CPQA 4LF5H 5FLXW 4G08A 1HR0H
chains in the Genus database with same CATH topology
4FJSA 2G8YA 3I0PA 1XRHA 4FJUA 2CWFA 1S20A 1Z2IA 2CWHA 2X06A 1X0AA 1WTJA 1V9NA 1VBIA 3UOEA 4H8AA 1NXUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FJS A;  2G8Y A;  3I0P A;  1XRH A;  4FJU A;  2CWF A;  1S20 A;  1Z2I A;  2CWH A;  2X06 A;  1X0A A;  1WTJ A;  1V9N A;  1VBI A;  3UOE A;  4H8A A;  1NXU A; 
#chains in the Genus database with same CATH topology
 2QND A;  5IWA H;  4DR4 H;  1XRH A;  2M6Q A;  2ZQE A;  2DGR A;  4B8C D;  2M8W A;  2UU9 H;  4NXM H;  5IT9 W;  4B3T H;  2JE6 I;  4E9J A;  3KDK A;  1X4N A;  4JI7 H;  4DR3 H;  2CTE A;  3RF2 A;  5K36 G;  4X64 H;  1MSZ A;  2JA9 A;  3L7Z C;  2D9I A;  1HNX H;  2BL5 A;  2LTM A;  1VIH A;  3KDG A;  3GAB A;  3I0P A;  1IBK H;  4LFB H;  4DR5 H;  4BA2 I;  2CTL A;  2JVZ A;  2OPV A;  4JV5 H;  2UXD H;  2JEB I;  4DV0 H;  4DV4 H;  4X66 H;  2UXB H;  2PY9 A;  2CTM A;  2LTL A;  1V8C A;  3JAM W;  1V9N A;  4NZT M;  4DV7 H;  4K0K H;  2Z0S A;  1F0X A;  4OCH A;  4AQY H;  1ODH A;  4JI5 H;  1K1G A;  3SB1 A;  2HH3 A;  3T1Y H;  1XNQ H;  2HH2 A;  4PDB A;  2O4C A;  2HHH H;  3OET A;  2JZX A;  4LFC H;  1XNR H;  4EC5 A;  4DV1 H;  5DT9 A;  1S03 G;  3V69 A;  1KHM A;  4OO1 G;  2CTF A;  1N36 H;  1S20 A;  4NXN H;  2JEA I;  4DUZ H;  4BA1 I;  2UXC H;  2CTK A;  4YHH H;  4JI6 H;  4B3M H;  2ZM6 H;  1FKA H;  1IBM H;  4DR6 H;  1HNW H;  2BA0 A;  2YQR A;  4WAL A;  2VQE H;  3J81 W;  1XMQ H;  4NZR M;  1FJG H;  1UG8 A;  4DV3 H;  2G8Y A;  4B3R H;  1DTJ A;  5LMU H;  4WAN A;  3J80 W;  1N32 H;  2FMR A;  4B3S H;  4IFD G;  2CPM A;  4X65 H;  1I94 H;  4DR1 H;  1NXU A;  4JI3 H;  4DV2 H;  1ZZK A;  3FAU A;  2NN6 G;  4LIJ A;  1XMO H;  1N34 H;  2LF0 A;  4OX9 H;  4OD6 A;  4LFA H;  3OTO H;  1J4W A;  1VIG A;  4JI0 H;  4GKJ H;  4QMF B;  4YY3 H;  2PQU A;  1AN7 A;  5JEA G;  3U1K A;  1TUA A;  4DUY H;  2P2R A;  4JI1 H;  4LF8 H;  2LRR A;  3QD7 X;  1SEI A;  3EZJ A;  1VBI A;  2E5L H;  4H8A A;  2CTJ A;  2UUB H;  1J5K A;  2FFM A;  2OPU A;  3VKE A;  1Z2I A;  4AIM A;  1ZTG A;  4JI2 H;  2K1H A;  2ANR A;  2ANN A;  1WVN A;  1HNZ H;  3AEV B;  2E3U A;  1X4M A;  4LF6 H;  4NBQ A;  4JYA H;  2VKC A;  2CWF A;  2CWH A;  2FPH X;  3J7A K;  3GKU A;  4GKK H;  4LF7 H;  2F4V H;  4DR2 H;  2UUA H;  4B8T A;  1X9Z A;  1WHR A;  5LL6 b;  3NCV A;  1WE8 A;  2VQF H;  1J5E H;  4JI4 H;  4JI8 H;  3OSS D;  2MJH A;  4LF4 H;  4FJS A;  3GR5 A;  2A1S A;  4DV5 H;  4DR7 H;  4JVH A;  4FJU A;  1EC6 A;  1X0A A;  1WTJ A;  1PQX A;  4AM3 A;  4JVY A;  5A2Q W;  5BR8 H;  2AXY A;  4X62 H;  4DV6 H;  4LF9 H;  4KHP H;  1N33 H;  5LMN H;  1DT4 A;  3T1H H;  1ZZJ A;  3UOE A;  1ZZI A;  2Y3M A;  1IBL H;  2PT7 G;  2UUC H;  5C0X G;  2X06 A;  1I6U A;  2CPQ A;  4LF5 H;  5FLX W;  4G08 A;  1HR0 H; 
#chains in the Genus database with same CATH homology
 4FJS A;  2G8Y A;  3I0P A;  1XRH A;  4FJU A;  2CWF A;  1S20 A;  1Z2I A;  2CWH A;  2X06 A;  1X0A A;  1WTJ A;  1V9N A;  1VBI A;  3UOE A;  4H8A A;  1NXU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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