1EC6A

Crystal structure of nova-2 kh3 k-homology rna-binding domain bound to 20-mer rna hairpin
Total Genus 27
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
87
structure length
87
Chain Sequence
MKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords 20-MER RNA HAIRPIN
total genus 27
structure length 87
sequence length 87
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 1ec6A00
2JEBI 3L7ZC 2OPVA 2Z0SA 4WALA 1X4NA 1DT4A 3V69A 2CTEA 3AEVB 5C0XG 3VKEA 4WANA 4LIJA 1ZZKA 1K1GA 1WVNA 1X4MA 2HH3A 5K36G 2CTMA 4OO1G 2YQRA 2JEAI 1VIGA 1ZZIA 2PY9A 1DTJA 2OPUA 4B8TA 2P2RA 2ANRA 3U1KA 4BA1I 4AIMA 2CTLA 1KHMA 2JZXA 2DGRA 2CPQA 2NN6G 4JVYA 2BL5A 4JVHA 1J5KA 2CTFA 2CTJA 2JE6I 2E3UA 2BA0A 2HH2A 2PQUA 2JVZA 4IFDG 1ZTGA 4NBQA 4AM3A 2CTKA 4QMFB 2AXYA 2FMRA 4BA2I 1WE8A 2QNDA 1VIHA 2ANNA 2JA9A 5JEAG 1J4WA 1ZZJA 1TUAA 2MJHA 1EC6A
chains in the Genus database with same CATH superfamily
2OPVA 1X4NA 5C0XG 3VKEA 2F4VH 3J80W 4G08A 2VQEH 1X4MA 2HH3A 4DR2H 4JYAH 2CTMA 2YQRA 1NXUA 1ZZIA 3EZJA 2HHHH 3J81W 3T1YH 4GKKH 4LFBH 1I6UA 4E9JA 1N34H 2ANRA 3GKUA 4BA1I 2VQFH 5LMUH 1X0AA 2G8YA 4JVYA 4DV2H 3UOEA 1ODHA 1J5KA 4DV5H 2CTJA 1SEIA 4LFAH 4B3SH 1AN7A 5IT9W 1MSZA 4NBQA 4DR6H 4QMFB 5LMNH 2FMRA 4YHHH 4JI3H 4LF8H 4DUZH 4JI0H 1HNWH 5DT9A 4JI7H 3SB1A 2P2RA 1EC6A 2JEBI 3AEVB 2Z0SA 4WALA 1PQXA 2ZQEA 3GABA 4DR1H 4KHPH 4DR3H 3OTOH 2PT7G 1K1GA 1WVNA 2FPHX 4NZRM 2VKCA 4DV6H 2CWHA 1WTJA 1VIGA 2LTMA 2OPUA 2UXCH 2CWFA 3T1HH 4JV5H 2LTLA 3U1KA 4DR4H 4LF9H 2DGRA 1XMOH 2BL5A 1HR0H 1VBIA 2A1SA 2FFMA 2UU9H 1UG8A 1FJGH 1N32H 1IBMH 1IBLH 1ZZJA 4K0KH 3OSSD 4X62H 4DV7H 1Z2IA 3I0PA 4B3TH 4AM3A 2UUAH 4JI8H 1XNQH 4X66H 2E5LH 2UUBH 1N36H 1V9NA 2JA9A 4EC5A 4NZTM 1J4WA 4OX9H 4X64H 3V69A 2CTEA 1FKAH 4NXMH 1XNRH 3JAMW 4X65H 3KDKA 4DV1H 1S20A 1X9ZA 4DR7H 2JEAI 2PY9A 4B3MH 3NCVA 2UXBH 3GR5A 1S03G 2ZM6H 4LF5H 4LFCH 5FLXW 4JI6H 4AIMA 2CTLA 4DUYH 4LF7H 1F0XA 2CPQA 2CPMA 2NN6G 4JI4H 4OD6A 4JVHA 2JE6I 2UUCH 4JI2H 2JVZA 4DR5H 3QD7X 5A2QW 4LF6H 4OCHA 2LRRA 2CTKA 2AXYA 4BA2I 1WE8A 2QNDA 1J5EH 4PDBA 1I94H 1TUAA 2MJHA 3J7AK 3L7ZC 1XMQH 4DV4H 1DT4A 5BR8H 4WANA 4LIJA 1ZZKA 3OETA 4FJUA 4JI5H 1WHRA 4DV0H 5K36G 4OO1G 1V8CA 3RF2A 1DTJA 4FJSA 4B8TA 2M8WA 4AQYH 3KDGA 2M6QA 4DV3H 2X06A 4GKJH 4NXNH 1IBKH 1KHMA 2JZXA 4YY3H 5LL6b 5IWAH 2CTFA 1HNZH 2K1HA 2E3UA 2BA0A 2HH2A 2PQUA 4IFDG 1ZTGA 4JI1H 2Y3MA 4B8CD 1VIHA 1XRHA 1HNXH 2ANNA 3FAUA 5JEAG 4B3RH 1N33H 2O4CA 2LF0A 4LF4H 2D9IA 2UXDH 4H8AA
chains in the Genus database with same CATH topology
2JEBI 3L7ZC 2OPVA 2Z0SA 4WALA 1X4NA 1DT4A 3V69A 2CTEA 3AEVB 5C0XG 3VKEA 4WANA 4LIJA 1ZZKA 1K1GA 1WVNA 1X4MA 2HH3A 5K36G 2CTMA 4OO1G 2YQRA 2JEAI 1VIGA 1ZZIA 2PY9A 1DTJA 2OPUA 4B8TA 2P2RA 2ANRA 3U1KA 4BA1I 4AIMA 2CTLA 1KHMA 2JZXA 2DGRA 2CPQA 2NN6G 4JVYA 2BL5A 4JVHA 1J5KA 2CTFA 2CTJA 2JE6I 2E3UA 2BA0A 2HH2A 2PQUA 2JVZA 4IFDG 1ZTGA 4NBQA 4AM3A 2CTKA 4QMFB 2AXYA 2FMRA 4BA2I 1WE8A 2QNDA 1VIHA 2ANNA 2JA9A 5JEAG 1J4WA 1ZZJA 1TUAA 2MJHA 1EC6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JEB I;  3L7Z C;  2OPV A;  2Z0S A;  4WAL A;  1X4N A;  1DT4 A;  3V69 A;  2CTE A;  3AEV B;  5C0X G;  3VKE A;  4WAN A;  4LIJ A;  1ZZK A;  1K1G A;  1WVN A;  1X4M A;  2HH3 A;  5K36 G;  2CTM A;  4OO1 G;  2YQR A;  2JEA I;  1VIG A;  1ZZI A;  2PY9 A;  1DTJ A;  2OPU A;  4B8T A;  2P2R A;  2ANR A;  3U1K A;  4BA1 I;  4AIM A;  2CTL A;  1KHM A;  2JZX A;  2DGR A;  2CPQ A;  2NN6 G;  4JVY A;  2BL5 A;  4JVH A;  1J5K A;  2CTF A;  2CTJ A;  2JE6 I;  2E3U A;  2BA0 A;  2HH2 A;  2PQU A;  2JVZ A;  4IFD G;  1ZTG A;  4NBQ A;  4AM3 A;  2CTK A;  4QMF B;  2AXY A;  2FMR A;  4BA2 I;  1WE8 A;  2QND A;  1VIH A;  2ANN A;  2JA9 A;  5JEA G;  1J4W A;  1ZZJ A;  1TUA A;  2MJH A;  1EC6 A; 
#chains in the Genus database with same CATH topology
 2OPV A;  1X4N A;  5C0X G;  3VKE A;  2F4V H;  3J80 W;  4G08 A;  2VQE H;  1X4M A;  2HH3 A;  4DR2 H;  4JYA H;  2CTM A;  2YQR A;  1NXU A;  1ZZI A;  3EZJ A;  2HHH H;  3J81 W;  3T1Y H;  4GKK H;  4LFB H;  1I6U A;  4E9J A;  1N34 H;  2ANR A;  3GKU A;  4BA1 I;  2VQF H;  5LMU H;  1X0A A;  2G8Y A;  4JVY A;  4DV2 H;  3UOE A;  1ODH A;  1J5K A;  4DV5 H;  2CTJ A;  1SEI A;  4LFA H;  4B3S H;  1AN7 A;  5IT9 W;  1MSZ A;  4NBQ A;  4DR6 H;  4QMF B;  5LMN H;  2FMR A;  4YHH H;  4JI3 H;  4LF8 H;  4DUZ H;  4JI0 H;  1HNW H;  5DT9 A;  4JI7 H;  3SB1 A;  2P2R A;  1EC6 A;  2JEB I;  3AEV B;  2Z0S A;  4WAL A;  1PQX A;  2ZQE A;  3GAB A;  4DR1 H;  4KHP H;  4DR3 H;  3OTO H;  2PT7 G;  1K1G A;  1WVN A;  2FPH X;  4NZR M;  2VKC A;  4DV6 H;  2CWH A;  1WTJ A;  1VIG A;  2LTM A;  2OPU A;  2UXC H;  2CWF A;  3T1H H;  4JV5 H;  2LTL A;  3U1K A;  4DR4 H;  4LF9 H;  2DGR A;  1XMO H;  2BL5 A;  1HR0 H;  1VBI A;  2A1S A;  2FFM A;  2UU9 H;  1UG8 A;  1FJG H;  1N32 H;  1IBM H;  1IBL H;  1ZZJ A;  4K0K H;  3OSS D;  4X62 H;  4DV7 H;  1Z2I A;  3I0P A;  4B3T H;  4AM3 A;  2UUA H;  4JI8 H;  1XNQ H;  4X66 H;  2E5L H;  2UUB H;  1N36 H;  1V9N A;  2JA9 A;  4EC5 A;  4NZT M;  1J4W A;  4OX9 H;  4X64 H;  3V69 A;  2CTE A;  1FKA H;  4NXM H;  1XNR H;  3JAM W;  4X65 H;  3KDK A;  4DV1 H;  1S20 A;  1X9Z A;  4DR7 H;  2JEA I;  2PY9 A;  4B3M H;  3NCV A;  2UXB H;  3GR5 A;  1S03 G;  2ZM6 H;  4LF5 H;  4LFC H;  5FLX W;  4JI6 H;  4AIM A;  2CTL A;  4DUY H;  4LF7 H;  1F0X A;  2CPQ A;  2CPM A;  2NN6 G;  4JI4 H;  4OD6 A;  4JVH A;  2JE6 I;  2UUC H;  4JI2 H;  2JVZ A;  4DR5 H;  3QD7 X;  5A2Q W;  4LF6 H;  4OCH A;  2LRR A;  2CTK A;  2AXY A;  4BA2 I;  1WE8 A;  2QND A;  1J5E H;  4PDB A;  1I94 H;  1TUA A;  2MJH A;  3J7A K;  3L7Z C;  1XMQ H;  4DV4 H;  1DT4 A;  5BR8 H;  4WAN A;  4LIJ A;  1ZZK A;  3OET A;  4FJU A;  4JI5 H;  1WHR A;  4DV0 H;  5K36 G;  4OO1 G;  1V8C A;  3RF2 A;  1DTJ A;  4FJS A;  4B8T A;  2M8W A;  4AQY H;  3KDG A;  2M6Q A;  4DV3 H;  2X06 A;  4GKJ H;  4NXN H;  1IBK H;  1KHM A;  2JZX A;  4YY3 H;  5LL6 b;  5IWA H;  2CTF A;  1HNZ H;  2K1H A;  2E3U A;  2BA0 A;  2HH2 A;  2PQU A;  4IFD G;  1ZTG A;  4JI1 H;  2Y3M A;  4B8C D;  1VIH A;  1XRH A;  1HNX H;  2ANN A;  3FAU A;  5JEA G;  4B3R H;  1N33 H;  2O4C A;  2LF0 A;  4LF4 H;  2D9I A;  2UXD H;  4H8A A; 
#chains in the Genus database with same CATH homology
 2JEB I;  3L7Z C;  2OPV A;  2Z0S A;  4WAL A;  1X4N A;  1DT4 A;  3V69 A;  2CTE A;  3AEV B;  5C0X G;  3VKE A;  4WAN A;  4LIJ A;  1ZZK A;  1K1G A;  1WVN A;  1X4M A;  2HH3 A;  5K36 G;  2CTM A;  4OO1 G;  2YQR A;  2JEA I;  1VIG A;  1ZZI A;  2PY9 A;  1DTJ A;  2OPU A;  4B8T A;  2P2R A;  2ANR A;  3U1K A;  4BA1 I;  4AIM A;  2CTL A;  1KHM A;  2JZX A;  2DGR A;  2CPQ A;  2NN6 G;  4JVY A;  2BL5 A;  4JVH A;  1J5K A;  2CTF A;  2CTJ A;  2JE6 I;  2E3U A;  2BA0 A;  2HH2 A;  2PQU A;  2JVZ A;  4IFD G;  1ZTG A;  4NBQ A;  4AM3 A;  2CTK A;  4QMF B;  2AXY A;  2FMR A;  4BA2 I;  1WE8 A;  2QND A;  1VIH A;  2ANN A;  2JA9 A;  5JEA G;  1J4W A;  1ZZJ A;  1TUA A;  2MJH A;  1EC6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...