1K1GA

Structural basis for recognition of the intron branch site rna by splicing factor 1
Total Genus 24
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
122
structure length
122
Chain Sequence
TRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recognition of the intron branch site RNA by splicing factor 1.
pubmed doi rcsb
molecule tags Gene regulation/rna
source organism Homo sapiens
molecule keywords 5'-R(*UP*AP*UP*AP*CP*UP*AP*AP*CP*AP*A)-3'
total genus 24
structure length 122
sequence length 122
ec nomenclature
pdb deposition date 2001-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 1k1gA00
2CPQA 5JEAG 2HH3A 1ZZKA 2JVZA 2OPUA 4BA1I 4BA2I 2E3UA 2JE6I 2JEBI 2AXYA 1K1GA 1ZZIA 2PQUA 1X4MA 1EC6A 1J5KA 4IFDG 5C0XG 2JEAI 1DTJA 1J4WA 1ZZJA 2ANNA 4AM3A 2CTFA 2QNDA 3AEVB 4JVHA 1DT4A 2PY9A 2CTJA 2HH2A 5K36G 1TUAA 2CTKA 4OO1G 2FMRA 4AIMA 1KHMA 2OPVA 2MJHA 3U1KA 4WANA 4NBQA 4LIJA 1WE8A 1VIGA 3VKEA 1X4NA 2CTEA 1VIHA 2ANRA 2YQRA 2CTLA 1WVNA 2BL5A 2CTMA 2NN6G 3L7ZC 4WALA 2JZXA 2Z0SA 4JVYA 4B8TA 1ZTGA 2DGRA 2JA9A 3V69A 2P2RA 2BA0A 4QMFB
chains in the Genus database with same CATH superfamily
2CPQA 2ZM6H 3JAMW 2VQFH 2JVZA 4NZRM 2JEBI 1K1GA 1EC6A 3GR5A 1ZZIA 1X4MA 1X9ZA 5LMNH 4GKKH 1AN7A 4DR7H 2JEAI 5LMUH 5IWAH 4LFCH 3EZJA 4B3RH 4DV4H 4DR2H 2PY9A 3J7AK 1TUAA 4OO1G 2UXCH 3KDGA 4NXNH 2UXDH 2UUAH 4WANA 2X06A 4DV5H 3OETA 4NBQA 4DR1H 1S20A 2ANRA 1X4NA 4FJUA 2LF0A 2M8WA 3NCVA 1IBLH 4JI6H 4X62H 4JVYA 1F0XA 2CPMA 2FPHX 4B8TA 1ZTGA 3I0PA 2P2RA 5A2QW 2LRRA 4QMFB 4OX9H 1ODHA 1N33H 3J81W 4DV1H 2G8YA 1HNZH 1XNQH 1IBKH 1VBIA 2E3UA 2PQUA 2E5LH 4DR6H 1FJGH 4DUZH 1HR0H 1XNRH 4LF5H 4IFDG 4LFBH 1J4WA 4FJSA 1S03G 3SB1A 4NZTM 5DT9A 2CTFA 2FFMA 4JVHA 2VQEH 4LF7H 1KHMA 2CTKA 5BR8H 2FMRA 3GABA 1V8CA 3V69A 2MJHA 4X65H 1XRHA 2CTEA 3RF2A 4LF9H 2BL5A 4X64H 4LF8H 2JZXA 2M6QA 1Z2IA 4E9JA 2ZQEA 2DGRA 2D9IA 3T1YH 3J80W 4DV2H 1N36H 2UUBH 5IT9W 1NXUA 2HHHH 1I6UA 2UU9H 5LL6b 4B3MH 2VKCA 1ZZKA 2OPUA 4BA2I 4KHPH 2JE6I 1HNXH 4AQYH 1DTJA 2UUCH 4AM3A 2O4CA 4B3TH 3AEVB 2HH2A 2CWFA 4DV6H 4K0KH 2OPVA 4OD6A 2UXBH 4DV7H 4JV5H 1WE8A 1SEIA 1VIHA 1MSZA 4JI2H 2YQRA 1N32H 4B3SH 4NXMH 4PDBA 2PT7G 2NN6G 1WVNA 2A1SA 2CTMA 2CWHA 3L7ZC 3QD7X 4DUYH 1HNWH 4JI5H 2JA9A 4YHHH 3FAUA 2Y3MA 4LFAH 2BA0A 4JI7H 4LF4H 1WTJA 3OSSD 4JI1H 5JEAG 4JI8H 2HH3A 5FLXW 4BA1I 4G08A 3UOEA 4B8CD 2AXYA 1I94H 1V9NA 1J5KA 5C0XG 2K1HA 2F4VH 1UG8A 4EC5A 1ZZJA 2ANNA 4YY3H 4JI4H 2LTMA 2QNDA 1DT4A 3KDKA 4DR4H 5K36G 2CTJA 4X66H 4GKJH 3T1HH 4H8AA 4AIMA 1XMOH 3U1KA 1PQXA 3OTOH 4LF6H 4JI0H 4LIJA 1VIGA 3VKEA 1FKAH 4DV3H 4JYAH 2LTLA 2CTLA 4DV0H 4DR5H 4DR3H 1WHRA 4JI3H 4WALA 2Z0SA 1IBMH 3GKUA 1XMQH 1J5EH 1N34H 1X0AA 4OCHA
chains in the Genus database with same CATH topology
2CPQA 5JEAG 2HH3A 1ZZKA 2JVZA 2OPUA 4BA1I 4BA2I 2E3UA 2JE6I 2JEBI 2AXYA 1K1GA 1ZZIA 2PQUA 1X4MA 1EC6A 1J5KA 4IFDG 5C0XG 2JEAI 1DTJA 1J4WA 1ZZJA 2ANNA 4AM3A 2CTFA 2QNDA 3AEVB 4JVHA 1DT4A 2PY9A 2CTJA 2HH2A 5K36G 1TUAA 2CTKA 4OO1G 2FMRA 4AIMA 1KHMA 2OPVA 2MJHA 3U1KA 4WANA 4NBQA 4LIJA 1WE8A 1VIGA 3VKEA 1X4NA 2CTEA 1VIHA 2ANRA 2YQRA 2CTLA 1WVNA 2BL5A 2CTMA 2NN6G 3L7ZC 4WALA 2JZXA 2Z0SA 4JVYA 4B8TA 1ZTGA 2DGRA 2JA9A 3V69A 2P2RA 2BA0A 4QMFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CPQ A;  5JEA G;  2HH3 A;  1ZZK A;  2JVZ A;  2OPU A;  4BA1 I;  4BA2 I;  2E3U A;  2JE6 I;  2JEB I;  2AXY A;  1K1G A;  1ZZI A;  2PQU A;  1X4M A;  1EC6 A;  1J5K A;  4IFD G;  5C0X G;  2JEA I;  1DTJ A;  1J4W A;  1ZZJ A;  2ANN A;  4AM3 A;  2CTF A;  2QND A;  3AEV B;  4JVH A;  1DT4 A;  2PY9 A;  2CTJ A;  2HH2 A;  5K36 G;  1TUA A;  2CTK A;  4OO1 G;  2FMR A;  4AIM A;  1KHM A;  2OPV A;  2MJH A;  3U1K A;  4WAN A;  4NBQ A;  4LIJ A;  1WE8 A;  1VIG A;  3VKE A;  1X4N A;  2CTE A;  1VIH A;  2ANR A;  2YQR A;  2CTL A;  1WVN A;  2BL5 A;  2CTM A;  2NN6 G;  3L7Z C;  4WAL A;  2JZX A;  2Z0S A;  4JVY A;  4B8T A;  1ZTG A;  2DGR A;  2JA9 A;  3V69 A;  2P2R A;  2BA0 A;  4QMF B; 
#chains in the Genus database with same CATH topology
 2CPQ A;  2ZM6 H;  3JAM W;  2VQF H;  2JVZ A;  4NZR M;  2JEB I;  1K1G A;  1EC6 A;  3GR5 A;  1ZZI A;  1X4M A;  1X9Z A;  5LMN H;  4GKK H;  1AN7 A;  4DR7 H;  2JEA I;  5LMU H;  5IWA H;  4LFC H;  3EZJ A;  4B3R H;  4DV4 H;  4DR2 H;  2PY9 A;  3J7A K;  1TUA A;  4OO1 G;  2UXC H;  3KDG A;  4NXN H;  2UXD H;  2UUA H;  4WAN A;  2X06 A;  4DV5 H;  3OET A;  4NBQ A;  4DR1 H;  1S20 A;  2ANR A;  1X4N A;  4FJU A;  2LF0 A;  2M8W A;  3NCV A;  1IBL H;  4JI6 H;  4X62 H;  4JVY A;  1F0X A;  2CPM A;  2FPH X;  4B8T A;  1ZTG A;  3I0P A;  2P2R A;  5A2Q W;  2LRR A;  4QMF B;  4OX9 H;  1ODH A;  1N33 H;  3J81 W;  4DV1 H;  2G8Y A;  1HNZ H;  1XNQ H;  1IBK H;  1VBI A;  2E3U A;  2PQU A;  2E5L H;  4DR6 H;  1FJG H;  4DUZ H;  1HR0 H;  1XNR H;  4LF5 H;  4IFD G;  4LFB H;  1J4W A;  4FJS A;  1S03 G;  3SB1 A;  4NZT M;  5DT9 A;  2CTF A;  2FFM A;  4JVH A;  2VQE H;  4LF7 H;  1KHM A;  2CTK A;  5BR8 H;  2FMR A;  3GAB A;  1V8C A;  3V69 A;  2MJH A;  4X65 H;  1XRH A;  2CTE A;  3RF2 A;  4LF9 H;  2BL5 A;  4X64 H;  4LF8 H;  2JZX A;  2M6Q A;  1Z2I A;  4E9J A;  2ZQE A;  2DGR A;  2D9I A;  3T1Y H;  3J80 W;  4DV2 H;  1N36 H;  2UUB H;  5IT9 W;  1NXU A;  2HHH H;  1I6U A;  2UU9 H;  5LL6 b;  4B3M H;  2VKC A;  1ZZK A;  2OPU A;  4BA2 I;  4KHP H;  2JE6 I;  1HNX H;  4AQY H;  1DTJ A;  2UUC H;  4AM3 A;  2O4C A;  4B3T H;  3AEV B;  2HH2 A;  2CWF A;  4DV6 H;  4K0K H;  2OPV A;  4OD6 A;  2UXB H;  4DV7 H;  4JV5 H;  1WE8 A;  1SEI A;  1VIH A;  1MSZ A;  4JI2 H;  2YQR A;  1N32 H;  4B3S H;  4NXM H;  4PDB A;  2PT7 G;  2NN6 G;  1WVN A;  2A1S A;  2CTM A;  2CWH A;  3L7Z C;  3QD7 X;  4DUY H;  1HNW H;  4JI5 H;  2JA9 A;  4YHH H;  3FAU A;  2Y3M A;  4LFA H;  2BA0 A;  4JI7 H;  4LF4 H;  1WTJ A;  3OSS D;  4JI1 H;  5JEA G;  4JI8 H;  2HH3 A;  5FLX W;  4BA1 I;  4G08 A;  3UOE A;  4B8C D;  2AXY A;  1I94 H;  1V9N A;  1J5K A;  5C0X G;  2K1H A;  2F4V H;  1UG8 A;  4EC5 A;  1ZZJ A;  2ANN A;  4YY3 H;  4JI4 H;  2LTM A;  2QND A;  1DT4 A;  3KDK A;  4DR4 H;  5K36 G;  2CTJ A;  4X66 H;  4GKJ H;  3T1H H;  4H8A A;  4AIM A;  1XMO H;  3U1K A;  1PQX A;  3OTO H;  4LF6 H;  4JI0 H;  4LIJ A;  1VIG A;  3VKE A;  1FKA H;  4DV3 H;  4JYA H;  2LTL A;  2CTL A;  4DV0 H;  4DR5 H;  4DR3 H;  1WHR A;  4JI3 H;  4WAL A;  2Z0S A;  1IBM H;  3GKU A;  1XMQ H;  1J5E H;  1N34 H;  1X0A A;  4OCH A; 
#chains in the Genus database with same CATH homology
 2CPQ A;  5JEA G;  2HH3 A;  1ZZK A;  2JVZ A;  2OPU A;  4BA1 I;  4BA2 I;  2E3U A;  2JE6 I;  2JEB I;  2AXY A;  1K1G A;  1ZZI A;  2PQU A;  1X4M A;  1EC6 A;  1J5K A;  4IFD G;  5C0X G;  2JEA I;  1DTJ A;  1J4W A;  1ZZJ A;  2ANN A;  4AM3 A;  2CTF A;  2QND A;  3AEV B;  4JVH A;  1DT4 A;  2PY9 A;  2CTJ A;  2HH2 A;  5K36 G;  1TUA A;  2CTK A;  4OO1 G;  2FMR A;  4AIM A;  1KHM A;  2OPV A;  2MJH A;  3U1K A;  4WAN A;  4NBQ A;  4LIJ A;  1WE8 A;  1VIG A;  3VKE A;  1X4N A;  2CTE A;  1VIH A;  2ANR A;  2YQR A;  2CTL A;  1WVN A;  2BL5 A;  2CTM A;  2NN6 G;  3L7Z C;  4WAL A;  2JZX A;  2Z0S A;  4JVY A;  4B8T A;  1ZTG A;  2DGR A;  2JA9 A;  3V69 A;  2P2R A;  2BA0 A;  4QMF B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...