1VBIA

Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus hb8
Total Genus 114
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
340
structure length
340
Chain Sequence
MRWRADFLSAWAEALLRKAGADEPSAKAVAWALVEADLRGVGSHGLLRLPVYVRRLEAGLVNPSPTLPLEERGPVALLDGEHGFGPRVALKAVEAAQSLARRHGLGAVGVRRSTHFGMAGLYAEKLAREGFVAWVTTNAEPDVVPFGGREKALGTNPLAFAAPAPQGILVADLATSESAMGKVFLAREKGERIPPSWGVDREGSPTDDPHRVYALRPLGGPKGYALALLVEVLSGVLTGAGVAHGIGRMYDEWDRPQDVGHFLLALDPGRFVGKEAFLERMGALWQALKATPPAPGHEEVFLPGELEARRRERALAEGMALPERVVAELKALGERYGVPW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus HB8
rcsb
molecule tags Oxidoreductase
source organism Thermus thermophilus
molecule keywords Type 2 malate/lactate dehydrogenase
total genus 114
structure length 340
sequence length 340
ec nomenclature ec 1.1.1.27: L-lactate dehydrogenase.
pdb deposition date 2004-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1vbiA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1vbiA02
1S20A 4FJUA 2CWHA 2CWFA 1X0AA 2X06A 1WTJA 1Z2IA 2G8YA 1VBIA 1V9NA 4H8AA 3I0PA 3UOEA 1NXUA 1XRHA 4FJSA
chains in the Genus database with same CATH superfamily
1IBKH 2CPMA 1ZTGA 5IWAH 2X06A 3T1HH 2Y3MA 1I6UA 4B8TA 4LF8H 4H8AA 3UOEA 4OCHA 2FFMA 1HR0H 4JI0H 5K36G 2UUCH 4AIMA 2Z0SA 3OTOH 1TUAA 4DV5H 2JVZA 5DT9A 4LIJA 4JI6H 2FPHX 1N36H 2CTMA 4AM3A 4LF9H 1F0XA 4NXMH 1K1GA 1EC6A 1ODHA 2CWFA 2HHHH 3EZJA 2CTEA 4K0KH 1VBIA 4DUYH 3OETA 1IBMH 4B3MH 2UXBH 1S20A 1AN7A 1XNRH 4AQYH 2BA0A 1WTJA 4PDBA 1DTJA 4OX9H 3JAMW 1J5EH 1ZZJA 1SEIA 4DR6H 1N32H 4LF6H 2CTJA 2VQEH 1FJGH 2UXCH 2M8WA 3KDKA 2OPVA 1X4MA 4JV5H 2LRRA 1ZZKA 2ANRA 1XNQH 4DR2H 2P2RA 5FLXW 1N33H 1V8CA 4OO1G 4B3SH 1Z2IA 2G8YA 4IFDG 3RF2A 2LTMA 1XMOH 4JI3H 4JI8H 3L7ZC 5C0XG 4JYAH 2E5LH 4DV0H 4X65H 4DV1H 2ZQEA 1I94H 4LFAH 1HNWH 2K1HA 4BA2I 1VIHA 5BR8H 4DV2H 2UUBH 4BA1I 1J4WA 4YHHH 4E9JA 2MJHA 4FJSA 2ZM6H 4GKJH 4X64H 2NN6G 2HH2A 4DV3H 4WALA 3FAUA 4JI1H 2PY9A 2JEBI 2CTLA 4JI4H 2OPUA 5LMUH 1NXUA 2F4VH 3GABA 3J81W 1ZZIA 2PQUA 1WHRA 3V69A 2BL5A 2D9IA 2PT7G 5A2QW 3I0PA 4DR7H 3NCVA 3GKUA 1J5KA 2M6QA 2LTLA 4FJUA 4JI7H 4LF4H 2JE6I 2JEAI 3OSSD 1FKAH 1IBLH 1V9NA 1WVNA 1KHMA 5LL6b 4DR5H 2CTKA 2DGRA 2VQFH 4JI5H 4JVYA 1X0AA 4LF7H 3KDGA 1X9ZA 2CTFA 4NZTM 4B8CD 2E3UA 2LF0A 4DR3H 4LFCH 4GKKH 4QMFB 4DR4H 2O4CA 3VKEA 2FMRA 4DR1H 1HNXH 1XRHA 1S03G 4NZRM 1WE8A 1HNZH 2UU9H 1VIGA 1X4NA 4LF5H 3GR5A 2CPQA 4X66H 4DV6H 4DV7H 3QD7X 4YY3H 5LMNH 4NXNH 4NBQA 2QNDA 4B3RH 3J7AK 3J80W 3SB1A 4EC5A 2VKCA 2ANNA 1UG8A 5JEAG 1XMQH 4DV4H 2YQRA 2A1SA 1DT4A 4X62H 4KHPH 3AEVB 4OD6A 3T1YH 3U1KA 1N34H 2JA9A 2CWHA 2JZXA 1MSZA 2AXYA 2UUAH 4B3TH 2UXDH 4WANA 4DUZH 4JVHA 2HH3A 4JI2H 4G08A 1PQXA 4LFBH 5IT9W
chains in the Genus database with same CATH topology
1S20A 4FJUA 2CWHA 2CWFA 1X0AA 2X06A 1WTJA 1Z2IA 2G8YA 1VBIA 1V9NA 4H8AA 3I0PA 3UOEA 1NXUA 1XRHA 4FJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S20 A;  4FJU A;  2CWH A;  2CWF A;  1X0A A;  2X06 A;  1WTJ A;  1Z2I A;  2G8Y A;  1VBI A;  1V9N A;  4H8A A;  3I0P A;  3UOE A;  1NXU A;  1XRH A;  4FJS A; 
#chains in the Genus database with same CATH topology
 1IBK H;  2CPM A;  1ZTG A;  5IWA H;  2X06 A;  3T1H H;  2Y3M A;  1I6U A;  4B8T A;  4LF8 H;  4H8A A;  3UOE A;  4OCH A;  2FFM A;  1HR0 H;  4JI0 H;  5K36 G;  2UUC H;  4AIM A;  2Z0S A;  3OTO H;  1TUA A;  4DV5 H;  2JVZ A;  5DT9 A;  4LIJ A;  4JI6 H;  2FPH X;  1N36 H;  2CTM A;  4AM3 A;  4LF9 H;  1F0X A;  4NXM H;  1K1G A;  1EC6 A;  1ODH A;  2CWF A;  2HHH H;  3EZJ A;  2CTE A;  4K0K H;  1VBI A;  4DUY H;  3OET A;  1IBM H;  4B3M H;  2UXB H;  1S20 A;  1AN7 A;  1XNR H;  4AQY H;  2BA0 A;  1WTJ A;  4PDB A;  1DTJ A;  4OX9 H;  3JAM W;  1J5E H;  1ZZJ A;  1SEI A;  4DR6 H;  1N32 H;  4LF6 H;  2CTJ A;  2VQE H;  1FJG H;  2UXC H;  2M8W A;  3KDK A;  2OPV A;  1X4M A;  4JV5 H;  2LRR A;  1ZZK A;  2ANR A;  1XNQ H;  4DR2 H;  2P2R A;  5FLX W;  1N33 H;  1V8C A;  4OO1 G;  4B3S H;  1Z2I A;  2G8Y A;  4IFD G;  3RF2 A;  2LTM A;  1XMO H;  4JI3 H;  4JI8 H;  3L7Z C;  5C0X G;  4JYA H;  2E5L H;  4DV0 H;  4X65 H;  4DV1 H;  2ZQE A;  1I94 H;  4LFA H;  1HNW H;  2K1H A;  4BA2 I;  1VIH A;  5BR8 H;  4DV2 H;  2UUB H;  4BA1 I;  1J4W A;  4YHH H;  4E9J A;  2MJH A;  4FJS A;  2ZM6 H;  4GKJ H;  4X64 H;  2NN6 G;  2HH2 A;  4DV3 H;  4WAL A;  3FAU A;  4JI1 H;  2PY9 A;  2JEB I;  2CTL A;  4JI4 H;  2OPU A;  5LMU H;  1NXU A;  2F4V H;  3GAB A;  3J81 W;  1ZZI A;  2PQU A;  1WHR A;  3V69 A;  2BL5 A;  2D9I A;  2PT7 G;  5A2Q W;  3I0P A;  4DR7 H;  3NCV A;  3GKU A;  1J5K A;  2M6Q A;  2LTL A;  4FJU A;  4JI7 H;  4LF4 H;  2JE6 I;  2JEA I;  3OSS D;  1FKA H;  1IBL H;  1V9N A;  1WVN A;  1KHM A;  5LL6 b;  4DR5 H;  2CTK A;  2DGR A;  2VQF H;  4JI5 H;  4JVY A;  1X0A A;  4LF7 H;  3KDG A;  1X9Z A;  2CTF A;  4NZT M;  4B8C D;  2E3U A;  2LF0 A;  4DR3 H;  4LFC H;  4GKK H;  4QMF B;  4DR4 H;  2O4C A;  3VKE A;  2FMR A;  4DR1 H;  1HNX H;  1XRH A;  1S03 G;  4NZR M;  1WE8 A;  1HNZ H;  2UU9 H;  1VIG A;  1X4N A;  4LF5 H;  3GR5 A;  2CPQ A;  4X66 H;  4DV6 H;  4DV7 H;  3QD7 X;  4YY3 H;  5LMN H;  4NXN H;  4NBQ A;  2QND A;  4B3R H;  3J7A K;  3J80 W;  3SB1 A;  4EC5 A;  2VKC A;  2ANN A;  1UG8 A;  5JEA G;  1XMQ H;  4DV4 H;  2YQR A;  2A1S A;  1DT4 A;  4X62 H;  4KHP H;  3AEV B;  4OD6 A;  3T1Y H;  3U1K A;  1N34 H;  2JA9 A;  2CWH A;  2JZX A;  1MSZ A;  2AXY A;  2UUA H;  4B3T H;  2UXD H;  4WAN A;  4DUZ H;  4JVH A;  2HH3 A;  4JI2 H;  4G08 A;  1PQX A;  4LFB H;  5IT9 W; 
#chains in the Genus database with same CATH homology
 1S20 A;  4FJU A;  2CWH A;  2CWF A;  1X0A A;  2X06 A;  1WTJ A;  1Z2I A;  2G8Y A;  1VBI A;  1V9N A;  4H8A A;  3I0P A;  3UOE A;  1NXU A;  1XRH A;  4FJS A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...