2ANNA

Crystal structure (i) of nova-1 kh1/kh2 domain tandem with 25 nt rna hairpin
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
175
structure length
148
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQNRVVTVSGEPEQNRKAVELIIQKIQEDP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
molecule tags Rna-binding protein/rna
source organism Homo sapiens
molecule keywords 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*
total genus 41
structure length 148
sequence length 175
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA02
2CTFA 4WANA 1ZTGA 1DTJA 2BL5A 3VKEA 2JE6I 2JEBI 4BA1I 2DGRA 1X4MA 4AIMA 2JA9A 2JZXA 2FMRA 2JVZA 3V69A 3AEVB 2OPUA 4BA2I 2YQRA 2OPVA 4LIJA 4AM3A 2E3UA 2MJHA 4IFDG 5K36G 3L7ZC 4OO1G 2CTEA 1VIHA 1DT4A 5C0XG 2CTLA 1ZZJA 2P2RA 4JVYA 1VIGA 2Z0SA 1WVNA 3U1KA 2QNDA 2HH3A 2CTKA 2BA0A 4B8TA 2ANRA 1J4WA 1K1GA 4WALA 1ZZIA 2PY9A 1EC6A 2CTJA 4NBQA 2ANNA 5JEAG 1KHMA 1ZZKA 1WE8A 2NN6G 1TUAA 2AXYA 1J5KA 2JEAI 2HH2A 2CTMA 4JVHA 2PQUA 2CPQA 1X4NA 4QMFB
chains in the Genus database with same CATH superfamily
5IWAH 3GABA 1DTJA 4B3TH 4LFCH 3VKEA 3OETA 2LRRA 4DR6H 3KDKA 2JEBI 4LFBH 2UXBH 4G08A 4AIMA 5BR8H 2LTMA 4X66H 3AEVB 4DV6H 2OPUA 3GKUA 4JI1H 2E3UA 5K36G 1HNXH 2D9IA 3L7ZC 4OO1G 1VIHA 1DT4A 3J81W 1ZZJA 5LMUH 2P2RA 4X65H 5LL6b 2E5LH 1WVNA 4KHPH 1PQXA 2LF0A 4DUZH 1Z2IA 4JI2H 2BA0A 3OSSD 2UUCH 1J4WA 1XMOH 1IBMH 4FJSA 4B3RH 2CTJA 3I0PA 1S03G 5JEAG 4X64H 2UUBH 2VKCA 1VBIA 1WHRA 4DV1H 4NXNH 4B3SH 4X62H 4LF5H 4JVHA 4DR1H 2UXDH 2CPQA 3EZJA 1X4NA 4B8TA 1IBKH 4WANA 4NZRM 1ZTGA 4JI5H 1NXUA 2UXCH 1XRHA 2JA9A 2FPHX 2FMRA 3T1YH 1I94H 3J80W 1ODHA 2A1SA 5DT9A 4OD6A 2VQFH 2YQRA 1XNQH 1X0AA 4DV5H 2CTEA 5C0XG 3NCVA 4DV7H 2CTLA 3J7AK 2Z0SA 4DR7H 4DV3H 3U1KA 3QD7X 3KDGA 4FJUA 2PY9A 1XMQH 1EC6A 2CWHA 2X06A 1AN7A 4NXMH 5IT9W 4JI8H 1HNWH 5FLXW 1FJGH 2AXYA 4LF8H 1J5KA 2JEAI 1UG8A 2PQUA 3T1HH 4GKJH 4QMFB 1N32H 3FAUA 2BL5A 2DGRA 2VQEH 2JZXA 2K1HA 4JI0H 4AQYH 1J5EH 3V69A 4DR4H 4B3MH 1N34H 4LIJA 4IFDG 2MJHA 4LF4H 4JI6H 3RF2A 1N33H 4LF7H 4YHHH 4JYAH 4K0KH 1VIGA 4JV5H 2QNDA 2ZQEA 4OX9H 1I6UA 4YY3H 1K1GA 1V9NA 1HR0H 1IBLH 4NBQA 1F0XA 2ANNA 1KHMA 3OTOH 1V8CA 1ZZKA 2FFMA 1WE8A 1MSZA 1TUAA 2HHHH 2M8WA 2HH2A 2Y3MA 4DUYH 2G8YA 2LTLA 1HNZH 2CTFA 4JI4H 5A2QW 5LMNH 4DR5H 2JE6I 4BA1I 1X4MA 2PT7G 4DV4H 2F4VH 1X9ZA 2UUAH 4OCHA 3GR5A 2CWFA 2JVZA 4B8CD 3JAMW 1N36H 4LFAH 4BA2I 2OPVA 4JI3H 4AM3A 4DV2H 2UU9H 4LF9H 2M6QA 4NZTM 4E9JA 4JI7H 4DV0H 1XNRH 4DR2H 1SEIA 4JVYA 4PDBA 4H8AA 2HH3A 2CTKA 3UOEA 2ANRA 4WALA 1ZZIA 4LF6H 1S20A 1WTJA 4EC5A 1FKAH 2NN6G 4DR3H 4GKKH 2CTMA 2ZM6H 2O4CA 2CPMA 3SB1A
chains in the Genus database with same CATH topology
2CTFA 4WANA 1ZTGA 1DTJA 2BL5A 3VKEA 2JE6I 2JEBI 4BA1I 2DGRA 1X4MA 4AIMA 2JA9A 2JZXA 2FMRA 2JVZA 3V69A 3AEVB 2OPUA 4BA2I 2YQRA 2OPVA 4LIJA 4AM3A 2E3UA 2MJHA 4IFDG 5K36G 3L7ZC 4OO1G 2CTEA 1VIHA 1DT4A 5C0XG 2CTLA 1ZZJA 2P2RA 4JVYA 1VIGA 2Z0SA 1WVNA 3U1KA 2QNDA 2HH3A 2CTKA 2BA0A 4B8TA 2ANRA 1J4WA 1K1GA 4WALA 1ZZIA 2PY9A 1EC6A 2CTJA 4NBQA 2ANNA 5JEAG 1KHMA 1ZZKA 1WE8A 2NN6G 1TUAA 2AXYA 1J5KA 2JEAI 2HH2A 2CTMA 4JVHA 2PQUA 2CPQA 1X4NA 4QMFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CTF A;  4WAN A;  1ZTG A;  1DTJ A;  2BL5 A;  3VKE A;  2JE6 I;  2JEB I;  4BA1 I;  2DGR A;  1X4M A;  4AIM A;  2JA9 A;  2JZX A;  2FMR A;  2JVZ A;  3V69 A;  3AEV B;  2OPU A;  4BA2 I;  2YQR A;  2OPV A;  4LIJ A;  4AM3 A;  2E3U A;  2MJH A;  4IFD G;  5K36 G;  3L7Z C;  4OO1 G;  2CTE A;  1VIH A;  1DT4 A;  5C0X G;  2CTL A;  1ZZJ A;  2P2R A;  4JVY A;  1VIG A;  2Z0S A;  1WVN A;  3U1K A;  2QND A;  2HH3 A;  2CTK A;  2BA0 A;  4B8T A;  2ANR A;  1J4W A;  1K1G A;  4WAL A;  1ZZI A;  2PY9 A;  1EC6 A;  2CTJ A;  4NBQ A;  2ANN A;  5JEA G;  1KHM A;  1ZZK A;  1WE8 A;  2NN6 G;  1TUA A;  2AXY A;  1J5K A;  2JEA I;  2HH2 A;  2CTM A;  4JVH A;  2PQU A;  2CPQ A;  1X4N A;  4QMF B; 
#chains in the Genus database with same CATH topology
 5IWA H;  3GAB A;  1DTJ A;  4B3T H;  4LFC H;  3VKE A;  3OET A;  2LRR A;  4DR6 H;  3KDK A;  2JEB I;  4LFB H;  2UXB H;  4G08 A;  4AIM A;  5BR8 H;  2LTM A;  4X66 H;  3AEV B;  4DV6 H;  2OPU A;  3GKU A;  4JI1 H;  2E3U A;  5K36 G;  1HNX H;  2D9I A;  3L7Z C;  4OO1 G;  1VIH A;  1DT4 A;  3J81 W;  1ZZJ A;  5LMU H;  2P2R A;  4X65 H;  5LL6 b;  2E5L H;  1WVN A;  4KHP H;  1PQX A;  2LF0 A;  4DUZ H;  1Z2I A;  4JI2 H;  2BA0 A;  3OSS D;  2UUC H;  1J4W A;  1XMO H;  1IBM H;  4FJS A;  4B3R H;  2CTJ A;  3I0P A;  1S03 G;  5JEA G;  4X64 H;  2UUB H;  2VKC A;  1VBI A;  1WHR A;  4DV1 H;  4NXN H;  4B3S H;  4X62 H;  4LF5 H;  4JVH A;  4DR1 H;  2UXD H;  2CPQ A;  3EZJ A;  1X4N A;  4B8T A;  1IBK H;  4WAN A;  4NZR M;  1ZTG A;  4JI5 H;  1NXU A;  2UXC H;  1XRH A;  2JA9 A;  2FPH X;  2FMR A;  3T1Y H;  1I94 H;  3J80 W;  1ODH A;  2A1S A;  5DT9 A;  4OD6 A;  2VQF H;  2YQR A;  1XNQ H;  1X0A A;  4DV5 H;  2CTE A;  5C0X G;  3NCV A;  4DV7 H;  2CTL A;  3J7A K;  2Z0S A;  4DR7 H;  4DV3 H;  3U1K A;  3QD7 X;  3KDG A;  4FJU A;  2PY9 A;  1XMQ H;  1EC6 A;  2CWH A;  2X06 A;  1AN7 A;  4NXM H;  5IT9 W;  4JI8 H;  1HNW H;  5FLX W;  1FJG H;  2AXY A;  4LF8 H;  1J5K A;  2JEA I;  1UG8 A;  2PQU A;  3T1H H;  4GKJ H;  4QMF B;  1N32 H;  3FAU A;  2BL5 A;  2DGR A;  2VQE H;  2JZX A;  2K1H A;  4JI0 H;  4AQY H;  1J5E H;  3V69 A;  4DR4 H;  4B3M H;  1N34 H;  4LIJ A;  4IFD G;  2MJH A;  4LF4 H;  4JI6 H;  3RF2 A;  1N33 H;  4LF7 H;  4YHH H;  4JYA H;  4K0K H;  1VIG A;  4JV5 H;  2QND A;  2ZQE A;  4OX9 H;  1I6U A;  4YY3 H;  1K1G A;  1V9N A;  1HR0 H;  1IBL H;  4NBQ A;  1F0X A;  2ANN A;  1KHM A;  3OTO H;  1V8C A;  1ZZK A;  2FFM A;  1WE8 A;  1MSZ A;  1TUA A;  2HHH H;  2M8W A;  2HH2 A;  2Y3M A;  4DUY H;  2G8Y A;  2LTL A;  1HNZ H;  2CTF A;  4JI4 H;  5A2Q W;  5LMN H;  4DR5 H;  2JE6 I;  4BA1 I;  1X4M A;  2PT7 G;  4DV4 H;  2F4V H;  1X9Z A;  2UUA H;  4OCH A;  3GR5 A;  2CWF A;  2JVZ A;  4B8C D;  3JAM W;  1N36 H;  4LFA H;  4BA2 I;  2OPV A;  4JI3 H;  4AM3 A;  4DV2 H;  2UU9 H;  4LF9 H;  2M6Q A;  4NZT M;  4E9J A;  4JI7 H;  4DV0 H;  1XNR H;  4DR2 H;  1SEI A;  4JVY A;  4PDB A;  4H8A A;  2HH3 A;  2CTK A;  3UOE A;  2ANR A;  4WAL A;  1ZZI A;  4LF6 H;  1S20 A;  1WTJ A;  4EC5 A;  1FKA H;  2NN6 G;  4DR3 H;  4GKK H;  2CTM A;  2ZM6 H;  2O4C A;  2CPM A;  3SB1 A; 
#chains in the Genus database with same CATH homology
 2CTF A;  4WAN A;  1ZTG A;  1DTJ A;  2BL5 A;  3VKE A;  2JE6 I;  2JEB I;  4BA1 I;  2DGR A;  1X4M A;  4AIM A;  2JA9 A;  2JZX A;  2FMR A;  2JVZ A;  3V69 A;  3AEV B;  2OPU A;  4BA2 I;  2YQR A;  2OPV A;  4LIJ A;  4AM3 A;  2E3U A;  2MJH A;  4IFD G;  5K36 G;  3L7Z C;  4OO1 G;  2CTE A;  1VIH A;  1DT4 A;  5C0X G;  2CTL A;  1ZZJ A;  2P2R A;  4JVY A;  1VIG A;  2Z0S A;  1WVN A;  3U1K A;  2QND A;  2HH3 A;  2CTK A;  2BA0 A;  4B8T A;  2ANR A;  1J4W A;  1K1G A;  4WAL A;  1ZZI A;  2PY9 A;  1EC6 A;  2CTJ A;  4NBQ A;  2ANN A;  5JEA G;  1KHM A;  1ZZK A;  1WE8 A;  2NN6 G;  1TUA A;  2AXY A;  1J5K A;  2JEA I;  2HH2 A;  2CTM A;  4JVH A;  2PQU A;  2CPQ A;  1X4N A;  4QMF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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