2FMRA

Kh1 from the fragile x protein fmr1, nmr, 18 structures
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
65
structure length
65
Chain Sequence
ASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords FMR1 PROTEIN
total genus 8
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 1997-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2fmrA00
2P2RA 5C0XG 2JEBI 1X4NA 4BA2I 2OPVA 2PQUA 2CTEA 4OO1G 3U1KA 2ANNA 2CTJA 2CTKA 1EC6A 3VKEA 1J4WA 2CTLA 2CTMA 1DTJA 2FMRA 4IFDG 1ZTGA 1KHMA 2E3UA 1ZZJA 2CPQA 4AIMA 5JEAG 1VIHA 2BL5A 2JE6I 2JZXA 2AXYA 4AM3A 4JVYA 1WE8A 2ANRA 2JA9A 4LIJA 4B8TA 4JVHA 4QMFB 2JEAI 2CTFA 2HH3A 2OPUA 3V69A 2YQRA 2Z0SA 1ZZKA 4BA1I 1J5KA 4WANA 2MJHA 3L7ZC 1ZZIA 3AEVB 1K1GA 1WVNA 1TUAA 2HH2A 1DT4A 2JVZA 2BA0A 5K36G 2QNDA 4WALA 2DGRA 1X4MA 2NN6G 2PY9A 1VIGA 4NBQA
chains in the Genus database with same CATH superfamily
2PT7G 3J80W 5IWAH 2P2RA 4B3MH 1X4NA 4NXNH 1PQXA 2O4CA 4JV5H 4DR3H 2UUBH 3U1KA 4JI6H 4LFCH 2VQEH 2FMRA 2E3UA 4JI8H 2CPQA 3J81W 2F4VH 4AM3A 2D9IA 2JZXA 1X0AA 3JAMW 3T1HH 1IBMH 1WE8A 1F0XA 5LL6b 2JA9A 1IBLH 4JVHA 4NZRM 2HH3A 1SEIA 1Z2IA 2M8WA 1ZZKA 4DV5H 4DV7H 4B3SH 4DV2H 1ZZIA 4DV3H 2LTLA 1WVNA 2ZM6H 2VQFH 4JI7H 3AEVB 1DT4A 2JVZA 4X65H 1WTJA 5K36G 1HNWH 3GABA 3OETA 4LFAH 3SB1A 4KHPH 3QD7X 2PY9A 3NCVA 4NBQA 2UXBH 2G8YA 1NXUA 4LF4H 2FPHX 4YHHH 5FLXW 4AQYH 4JI0H 4JI1H 5LMUH 2ANNA 4LF8H 4JYAH 1J4WA 1HNZH 1DTJA 2CTMA 1XNQH 4B3RH 1S03G 1N32H 1ZTGA 4E9JA 2AXYA 5IT9W 1VIHA 2BL5A 4JI3H 2VKCA 2CPMA 2Y3MA 3GKUA 1XMQH 2ANRA 2CTFA 4NZTM 3KDGA 4X62H 3FAUA 3UOEA 1J5KA 3L7ZC 4EC5A 4G08A 4LF9H 2UUCH 2X06A 1XRHA 2M6QA 4DR5H 4DUYH 3RF2A 1N36H 2QNDA 2DGRA 4DR7H 2ZQEA 2JEBI 1V8CA 5C0XG 2OPVA 4FJUA 2CTEA 4DR6H 4OCHA 4PDBA 1N34H 3T1YH 2UXDH 1EC6A 1FKAH 2CWHA 4IFDG 1HR0H 4JI5H 1N33H 1HNXH 1VBIA 2UU9H 4JVYA 3OSSD 1X9ZA 4JI4H 4B8TA 4B3TH 2JEAI 2UXCH 1UG8A 4DV1H 3V69A 4DUZH 2Z0SA 4WANA 3I0PA 4LF5H 4DR4H 1TUAA 2HH2A 5LMNH 2BA0A 4DR1H 5BR8H 4WALA 1J5EH 3OTOH 2NN6G 1AN7A 1I6UA 4B8CD 4GKJH 2K1HA 4OO1G 4BA2I 2PQUA 4LF6H 1XNRH 4OX9H 1MSZA 1ODHA 2CTJA 2CTKA 2FFMA 4OD6A 2LF0A 2CTLA 4H8AA 3GR5A 4JI2H 3EZJA 3VKEA 1FJGH 1KHMA 1ZZJA 4AIMA 5JEAG 2HHHH 4DV6H 2JE6I 3J7AK 4DV0H 2UUAH 4K0KH 1IBKH 2LRRA 4LIJA 4NXMH 4LFBH 4DV4H 1WHRA 4QMFB 1V9NA 2OPUA 2YQRA 4X66H 2LTMA 4BA1I 5A2QW 1S20A 2MJHA 4YY3H 4X64H 2A1SA 4GKKH 4DR2H 1K1GA 2E5LH 5DT9A 1XMOH 4LF7H 1X4MA 3KDKA 1VIGA 2CWFA 4FJSA 1I94H
chains in the Genus database with same CATH topology
2P2RA 5C0XG 2JEBI 1X4NA 4BA2I 2OPVA 2PQUA 2CTEA 4OO1G 3U1KA 2ANNA 2CTJA 2CTKA 1EC6A 3VKEA 1J4WA 2CTLA 2CTMA 1DTJA 2FMRA 4IFDG 1ZTGA 1KHMA 2E3UA 1ZZJA 2CPQA 4AIMA 5JEAG 1VIHA 2BL5A 2JE6I 2JZXA 2AXYA 4AM3A 4JVYA 1WE8A 2ANRA 2JA9A 4LIJA 4B8TA 4JVHA 4QMFB 2JEAI 2CTFA 2HH3A 2OPUA 3V69A 2YQRA 2Z0SA 1ZZKA 4BA1I 1J5KA 4WANA 2MJHA 3L7ZC 1ZZIA 3AEVB 1K1GA 1WVNA 1TUAA 2HH2A 1DT4A 2JVZA 2BA0A 5K36G 2QNDA 4WALA 2DGRA 1X4MA 2NN6G 2PY9A 1VIGA 4NBQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P2R A;  5C0X G;  2JEB I;  1X4N A;  4BA2 I;  2OPV A;  2PQU A;  2CTE A;  4OO1 G;  3U1K A;  2ANN A;  2CTJ A;  2CTK A;  1EC6 A;  3VKE A;  1J4W A;  2CTL A;  2CTM A;  1DTJ A;  2FMR A;  4IFD G;  1ZTG A;  1KHM A;  2E3U A;  1ZZJ A;  2CPQ A;  4AIM A;  5JEA G;  1VIH A;  2BL5 A;  2JE6 I;  2JZX A;  2AXY A;  4AM3 A;  4JVY A;  1WE8 A;  2ANR A;  2JA9 A;  4LIJ A;  4B8T A;  4JVH A;  4QMF B;  2JEA I;  2CTF A;  2HH3 A;  2OPU A;  3V69 A;  2YQR A;  2Z0S A;  1ZZK A;  4BA1 I;  1J5K A;  4WAN A;  2MJH A;  3L7Z C;  1ZZI A;  3AEV B;  1K1G A;  1WVN A;  1TUA A;  2HH2 A;  1DT4 A;  2JVZ A;  2BA0 A;  5K36 G;  2QND A;  4WAL A;  2DGR A;  1X4M A;  2NN6 G;  2PY9 A;  1VIG A;  4NBQ A; 
#chains in the Genus database with same CATH topology
 2PT7 G;  3J80 W;  5IWA H;  2P2R A;  4B3M H;  1X4N A;  4NXN H;  1PQX A;  2O4C A;  4JV5 H;  4DR3 H;  2UUB H;  3U1K A;  4JI6 H;  4LFC H;  2VQE H;  2FMR A;  2E3U A;  4JI8 H;  2CPQ A;  3J81 W;  2F4V H;  4AM3 A;  2D9I A;  2JZX A;  1X0A A;  3JAM W;  3T1H H;  1IBM H;  1WE8 A;  1F0X A;  5LL6 b;  2JA9 A;  1IBL H;  4JVH A;  4NZR M;  2HH3 A;  1SEI A;  1Z2I A;  2M8W A;  1ZZK A;  4DV5 H;  4DV7 H;  4B3S H;  4DV2 H;  1ZZI A;  4DV3 H;  2LTL A;  1WVN A;  2ZM6 H;  2VQF H;  4JI7 H;  3AEV B;  1DT4 A;  2JVZ A;  4X65 H;  1WTJ A;  5K36 G;  1HNW H;  3GAB A;  3OET A;  4LFA H;  3SB1 A;  4KHP H;  3QD7 X;  2PY9 A;  3NCV A;  4NBQ A;  2UXB H;  2G8Y A;  1NXU A;  4LF4 H;  2FPH X;  4YHH H;  5FLX W;  4AQY H;  4JI0 H;  4JI1 H;  5LMU H;  2ANN A;  4LF8 H;  4JYA H;  1J4W A;  1HNZ H;  1DTJ A;  2CTM A;  1XNQ H;  4B3R H;  1S03 G;  1N32 H;  1ZTG A;  4E9J A;  2AXY A;  5IT9 W;  1VIH A;  2BL5 A;  4JI3 H;  2VKC A;  2CPM A;  2Y3M A;  3GKU A;  1XMQ H;  2ANR A;  2CTF A;  4NZT M;  3KDG A;  4X62 H;  3FAU A;  3UOE A;  1J5K A;  3L7Z C;  4EC5 A;  4G08 A;  4LF9 H;  2UUC H;  2X06 A;  1XRH A;  2M6Q A;  4DR5 H;  4DUY H;  3RF2 A;  1N36 H;  2QND A;  2DGR A;  4DR7 H;  2ZQE A;  2JEB I;  1V8C A;  5C0X G;  2OPV A;  4FJU A;  2CTE A;  4DR6 H;  4OCH A;  4PDB A;  1N34 H;  3T1Y H;  2UXD H;  1EC6 A;  1FKA H;  2CWH A;  4IFD G;  1HR0 H;  4JI5 H;  1N33 H;  1HNX H;  1VBI A;  2UU9 H;  4JVY A;  3OSS D;  1X9Z A;  4JI4 H;  4B8T A;  4B3T H;  2JEA I;  2UXC H;  1UG8 A;  4DV1 H;  3V69 A;  4DUZ H;  2Z0S A;  4WAN A;  3I0P A;  4LF5 H;  4DR4 H;  1TUA A;  2HH2 A;  5LMN H;  2BA0 A;  4DR1 H;  5BR8 H;  4WAL A;  1J5E H;  3OTO H;  2NN6 G;  1AN7 A;  1I6U A;  4B8C D;  4GKJ H;  2K1H A;  4OO1 G;  4BA2 I;  2PQU A;  4LF6 H;  1XNR H;  4OX9 H;  1MSZ A;  1ODH A;  2CTJ A;  2CTK A;  2FFM A;  4OD6 A;  2LF0 A;  2CTL A;  4H8A A;  3GR5 A;  4JI2 H;  3EZJ A;  3VKE A;  1FJG H;  1KHM A;  1ZZJ A;  4AIM A;  5JEA G;  2HHH H;  4DV6 H;  2JE6 I;  3J7A K;  4DV0 H;  2UUA H;  4K0K H;  1IBK H;  2LRR A;  4LIJ A;  4NXM H;  4LFB H;  4DV4 H;  1WHR A;  4QMF B;  1V9N A;  2OPU A;  2YQR A;  4X66 H;  2LTM A;  4BA1 I;  5A2Q W;  1S20 A;  2MJH A;  4YY3 H;  4X64 H;  2A1S A;  4GKK H;  4DR2 H;  1K1G A;  2E5L H;  5DT9 A;  1XMO H;  4LF7 H;  1X4M A;  3KDK A;  1VIG A;  2CWF A;  4FJS A;  1I94 H; 
#chains in the Genus database with same CATH homology
 2P2R A;  5C0X G;  2JEB I;  1X4N A;  4BA2 I;  2OPV A;  2PQU A;  2CTE A;  4OO1 G;  3U1K A;  2ANN A;  2CTJ A;  2CTK A;  1EC6 A;  3VKE A;  1J4W A;  2CTL A;  2CTM A;  1DTJ A;  2FMR A;  4IFD G;  1ZTG A;  1KHM A;  2E3U A;  1ZZJ A;  2CPQ A;  4AIM A;  5JEA G;  1VIH A;  2BL5 A;  2JE6 I;  2JZX A;  2AXY A;  4AM3 A;  4JVY A;  1WE8 A;  2ANR A;  2JA9 A;  4LIJ A;  4B8T A;  4JVH A;  4QMF B;  2JEA I;  2CTF A;  2HH3 A;  2OPU A;  3V69 A;  2YQR A;  2Z0S A;  1ZZK A;  4BA1 I;  1J5K A;  4WAN A;  2MJH A;  3L7Z C;  1ZZI A;  3AEV B;  1K1G A;  1WVN A;  1TUA A;  2HH2 A;  1DT4 A;  2JVZ A;  2BA0 A;  5K36 G;  2QND A;  4WAL A;  2DGR A;  1X4M A;  2NN6 G;  2PY9 A;  1VIG A;  4NBQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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