2FMRA

Kh1 from the fragile x protein fmr1, nmr, 18 structures
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
65
structure length
65
Chain Sequence
ASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords FMR1 PROTEIN
total genus 8
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 1997-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2fmrA00
2CTMA 4LIJA 2PQUA 2CPQA 2JA9A 1ZZKA 2Z0SA 1ZZJA 4WALA 2YQRA 5C0XG 4OO1G 2QNDA 5JEAG 5K36G 2E3UA 1TUAA 4JVHA 2P2RA 2CTFA 1ZZIA 2BL5A 1J5KA 4AIMA 2CTEA 2ANRA 2JVZA 1DTJA 2AXYA 2ANNA 2HH2A 1K1GA 4BA2I 2HH3A 2JE6I 4BA1I 2OPVA 2PY9A 2DGRA 1EC6A 2JEAI 2OPUA 2MJHA 3V69A 2FMRA 4IFDG 3L7ZC 4QMFB 3AEVB 1VIGA 2CTJA 1X4MA 1X4NA 2BA0A 2CTLA 4AM3A 1WVNA 4JVYA 1J4WA 1ZTGA 1KHMA 3VKEA 1WE8A 1VIHA 2JEBI 2CTKA 2JZXA 1DT4A 2NN6G 3U1KA 4NBQA 4WANA 4B8TA
chains in the Genus database with same CATH superfamily
1F0XA 4DR3H 2CWHA 1IBLH 2Z0SA 4LFAH 4AQYH 4KHPH 4WALA 2K1HA 2YQRA 3KDKA 2M6QA 4X65H 3OETA 2UXDH 4JI1H 4LF4H 2CTFA 4DV5H 4LF8H 2LF0A 2UUBH 1K1GA 4K0KH 4DR2H 2UU9H 2M8WA 4DUZH 2Y3MA 3J80W 2DGRA 1N34H 4LF5H 1HNWH 2OPUA 4EC5A 3OTOH 4JV5H 3JAMW 4E9JA 3AEVB 2LTMA 1Z2IA 4DV0H 1N36H 1FJGH 1KHMA 4B3MH 1WE8A 1VIHA 3RF2A 5LMUH 1S20A 2FFMA 4JI4H 5DT9A 2CWFA 3GR5A 4X66H 4OO1G 4B3TH 3QD7X 3T1HH 1IBMH 2UXBH 1WHRA 1N33H 4DV3H 1TUAA 4JI8H 3NCVA 4DV7H 4PDBA 1J5KA 4DR4H 2CTEA 4LF7H 2ANNA 2AXYA 1XNQH 4GKJH 2E5LH 1I94H 5IT9W 2G8YA 2X06A 4BA2I 1HNXH 2F4VH 2JE6I 4BA1I 4LF6H 4JI0H 4NXNH 3V69A 4IFDG 2LRRA 5BR8H 4QMFB 1VIGA 1AN7A 4OX9H 1WTJA 2VKCA 1NXUA 4X64H 1XNRH 2NN6G 1X9ZA 2CTKA 1I6UA 2O4CA 5LMNH 3T1YH 4NBQA 4YHHH 3J81W 4LIJA 2PQUA 4DV6H 4X62H 4JI2H 3UOEA 4GKKH 1UG8A 4NZRM 2QNDA 5JEAG 5C0XG 4DV1H 4NXMH 2E3UA 2VQEH 2P2RA 1S03G 2BL5A 4AIMA 2ANRA 4OCHA 4DUYH 3FAUA 2UXCH 2HH2A 4DR1H 1HR0H 2VQFH 1VBIA 3KDGA 3OSSD 5A2QW 2PY9A 4JI7H 4DV2H 3L7ZC 1SEIA 4FJUA 1XRHA 3GKUA 1MSZA 1X4MA 1X4NA 4DR6H 4NZTM 1PQXA 4LFCH 2CTLA 3GABA 1WVNA 4AM3A 1J4WA 1ZTGA 2CPMA 2ZQEA 3U1KA 1DT4A 5IWAH 3EZJA 4B8TA 4B8CD 2HHHH 2CTMA 1ODHA 2CPQA 2JA9A 1ZZKA 4YY3H 1ZZJA 4JYAH 3SB1A 4DV4H 5K36G 1XMQH 4JVHA 2UUAH 1ZZIA 4G08A 4JI6H 2LTLA 4B3SH 4JI5H 2JVZA 1DTJA 4LF9H 1XMOH 4B3RH 2A1SA 2HH3A 4H8AA 2OPVA 1J5EH 1V8CA 1EC6A 2JEAI 1IBKH 2MJHA 2FMRA 5LL6b 2D9IA 4JI3H 1X0AA 4OD6A 1V9NA 2FPHX 3I0PA 2CTJA 2BA0A 2PT7G 4JVYA 2UUCH 4DR7H 3VKEA 1N32H 4LFBH 2JEBI 2JZXA 4DR5H 1HNZH 1FKAH 2ZM6H 4WANA 4FJSA 3J7AK 5FLXW
chains in the Genus database with same CATH topology
2CTMA 4LIJA 2PQUA 2CPQA 2JA9A 1ZZKA 2Z0SA 1ZZJA 4WALA 2YQRA 5C0XG 4OO1G 2QNDA 5JEAG 5K36G 2E3UA 1TUAA 4JVHA 2P2RA 2CTFA 1ZZIA 2BL5A 1J5KA 4AIMA 2CTEA 2ANRA 2JVZA 1DTJA 2AXYA 2ANNA 2HH2A 1K1GA 4BA2I 2HH3A 2JE6I 4BA1I 2OPVA 2PY9A 2DGRA 1EC6A 2JEAI 2OPUA 2MJHA 3V69A 2FMRA 4IFDG 3L7ZC 4QMFB 3AEVB 1VIGA 2CTJA 1X4MA 1X4NA 2BA0A 2CTLA 4AM3A 1WVNA 4JVYA 1J4WA 1ZTGA 1KHMA 3VKEA 1WE8A 1VIHA 2JEBI 2CTKA 2JZXA 1DT4A 2NN6G 3U1KA 4NBQA 4WANA 4B8TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CTM A;  4LIJ A;  2PQU A;  2CPQ A;  2JA9 A;  1ZZK A;  2Z0S A;  1ZZJ A;  4WAL A;  2YQR A;  5C0X G;  4OO1 G;  2QND A;  5JEA G;  5K36 G;  2E3U A;  1TUA A;  4JVH A;  2P2R A;  2CTF A;  1ZZI A;  2BL5 A;  1J5K A;  4AIM A;  2CTE A;  2ANR A;  2JVZ A;  1DTJ A;  2AXY A;  2ANN A;  2HH2 A;  1K1G A;  4BA2 I;  2HH3 A;  2JE6 I;  4BA1 I;  2OPV A;  2PY9 A;  2DGR A;  1EC6 A;  2JEA I;  2OPU A;  2MJH A;  3V69 A;  2FMR A;  4IFD G;  3L7Z C;  4QMF B;  3AEV B;  1VIG A;  2CTJ A;  1X4M A;  1X4N A;  2BA0 A;  2CTL A;  4AM3 A;  1WVN A;  4JVY A;  1J4W A;  1ZTG A;  1KHM A;  3VKE A;  1WE8 A;  1VIH A;  2JEB I;  2CTK A;  2JZX A;  1DT4 A;  2NN6 G;  3U1K A;  4NBQ A;  4WAN A;  4B8T A; 
#chains in the Genus database with same CATH topology
 1F0X A;  4DR3 H;  2CWH A;  1IBL H;  2Z0S A;  4LFA H;  4AQY H;  4KHP H;  4WAL A;  2K1H A;  2YQR A;  3KDK A;  2M6Q A;  4X65 H;  3OET A;  2UXD H;  4JI1 H;  4LF4 H;  2CTF A;  4DV5 H;  4LF8 H;  2LF0 A;  2UUB H;  1K1G A;  4K0K H;  4DR2 H;  2UU9 H;  2M8W A;  4DUZ H;  2Y3M A;  3J80 W;  2DGR A;  1N34 H;  4LF5 H;  1HNW H;  2OPU A;  4EC5 A;  3OTO H;  4JV5 H;  3JAM W;  4E9J A;  3AEV B;  2LTM A;  1Z2I A;  4DV0 H;  1N36 H;  1FJG H;  1KHM A;  4B3M H;  1WE8 A;  1VIH A;  3RF2 A;  5LMU H;  1S20 A;  2FFM A;  4JI4 H;  5DT9 A;  2CWF A;  3GR5 A;  4X66 H;  4OO1 G;  4B3T H;  3QD7 X;  3T1H H;  1IBM H;  2UXB H;  1WHR A;  1N33 H;  4DV3 H;  1TUA A;  4JI8 H;  3NCV A;  4DV7 H;  4PDB A;  1J5K A;  4DR4 H;  2CTE A;  4LF7 H;  2ANN A;  2AXY A;  1XNQ H;  4GKJ H;  2E5L H;  1I94 H;  5IT9 W;  2G8Y A;  2X06 A;  4BA2 I;  1HNX H;  2F4V H;  2JE6 I;  4BA1 I;  4LF6 H;  4JI0 H;  4NXN H;  3V69 A;  4IFD G;  2LRR A;  5BR8 H;  4QMF B;  1VIG A;  1AN7 A;  4OX9 H;  1WTJ A;  2VKC A;  1NXU A;  4X64 H;  1XNR H;  2NN6 G;  1X9Z A;  2CTK A;  1I6U A;  2O4C A;  5LMN H;  3T1Y H;  4NBQ A;  4YHH H;  3J81 W;  4LIJ A;  2PQU A;  4DV6 H;  4X62 H;  4JI2 H;  3UOE A;  4GKK H;  1UG8 A;  4NZR M;  2QND A;  5JEA G;  5C0X G;  4DV1 H;  4NXM H;  2E3U A;  2VQE H;  2P2R A;  1S03 G;  2BL5 A;  4AIM A;  2ANR A;  4OCH A;  4DUY H;  3FAU A;  2UXC H;  2HH2 A;  4DR1 H;  1HR0 H;  2VQF H;  1VBI A;  3KDG A;  3OSS D;  5A2Q W;  2PY9 A;  4JI7 H;  4DV2 H;  3L7Z C;  1SEI A;  4FJU A;  1XRH A;  3GKU A;  1MSZ A;  1X4M A;  1X4N A;  4DR6 H;  4NZT M;  1PQX A;  4LFC H;  2CTL A;  3GAB A;  1WVN A;  4AM3 A;  1J4W A;  1ZTG A;  2CPM A;  2ZQE A;  3U1K A;  1DT4 A;  5IWA H;  3EZJ A;  4B8T A;  4B8C D;  2HHH H;  2CTM A;  1ODH A;  2CPQ A;  2JA9 A;  1ZZK A;  4YY3 H;  1ZZJ A;  4JYA H;  3SB1 A;  4DV4 H;  5K36 G;  1XMQ H;  4JVH A;  2UUA H;  1ZZI A;  4G08 A;  4JI6 H;  2LTL A;  4B3S H;  4JI5 H;  2JVZ A;  1DTJ A;  4LF9 H;  1XMO H;  4B3R H;  2A1S A;  2HH3 A;  4H8A A;  2OPV A;  1J5E H;  1V8C A;  1EC6 A;  2JEA I;  1IBK H;  2MJH A;  2FMR A;  5LL6 b;  2D9I A;  4JI3 H;  1X0A A;  4OD6 A;  1V9N A;  2FPH X;  3I0P A;  2CTJ A;  2BA0 A;  2PT7 G;  4JVY A;  2UUC H;  4DR7 H;  3VKE A;  1N32 H;  4LFB H;  2JEB I;  2JZX A;  4DR5 H;  1HNZ H;  1FKA H;  2ZM6 H;  4WAN A;  4FJS A;  3J7A K;  5FLX W; 
#chains in the Genus database with same CATH homology
 2CTM A;  4LIJ A;  2PQU A;  2CPQ A;  2JA9 A;  1ZZK A;  2Z0S A;  1ZZJ A;  4WAL A;  2YQR A;  5C0X G;  4OO1 G;  2QND A;  5JEA G;  5K36 G;  2E3U A;  1TUA A;  4JVH A;  2P2R A;  2CTF A;  1ZZI A;  2BL5 A;  1J5K A;  4AIM A;  2CTE A;  2ANR A;  2JVZ A;  1DTJ A;  2AXY A;  2ANN A;  2HH2 A;  1K1G A;  4BA2 I;  2HH3 A;  2JE6 I;  4BA1 I;  2OPV A;  2PY9 A;  2DGR A;  1EC6 A;  2JEA I;  2OPU A;  2MJH A;  3V69 A;  2FMR A;  4IFD G;  3L7Z C;  4QMF B;  3AEV B;  1VIG A;  2CTJ A;  1X4M A;  1X4N A;  2BA0 A;  2CTL A;  4AM3 A;  1WVN A;  4JVY A;  1J4W A;  1ZTG A;  1KHM A;  3VKE A;  1WE8 A;  1VIH A;  2JEB I;  2CTK A;  2JZX A;  1DT4 A;  2NN6 G;  3U1K A;  4NBQ A;  4WAN A;  4B8T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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