2HH2A

Solution structure of the fourth kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
79
structure length
79
Chain Sequence
GEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 79
sequence length 79
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh2A00
5JEAG 2JZXA 4WANA 4JVYA 1X4MA 1TUAA 4NBQA 4OO1G 2Z0SA 2E3UA 2ANNA 2HH2A 1WVNA 2CPQA 2CTEA 1ZTGA 4BA2I 3VKEA 1KHMA 2CTFA 2HH3A 2JE6I 2PY9A 2CTJA 5K36G 4BA1I 2MJHA 4WALA 4B8TA 1VIHA 1J4WA 2PQUA 1ZZKA 1ZZJA 4LIJA 2JEAI 3AEVB 4AM3A 2CTKA 4JVHA 1K1GA 1X4NA 1VIGA 2OPVA 2BA0A 1DTJA 2BL5A 1EC6A 1DT4A 2FMRA 2NN6G 3L7ZC 2ANRA 2JA9A 2DGRA 2QNDA 2CTMA 2JEBI 2YQRA 1J5KA 2JVZA 2CTLA 4IFDG 3U1KA 3V69A 4AIMA 2P2RA 4QMFB 1WE8A 2OPUA 5C0XG 2AXYA 1ZZIA
chains in the Genus database with same CATH superfamily
1V8CA 2UUCH 1V9NA 2UUAH 2E3UA 3J7AK 2CPQA 1UG8A 3JAMW 1KHMA 4X62H 1XMQH 4LF7H 4JI1H 4BA1I 2MJHA 2LRRA 4OX9H 1J4WA 1VIHA 3OETA 4GKJH 4X65H 4AM3A 4JVHA 1HNWH 1S20A 3EZJA 4DV3H 1VIGA 2M6QA 5DT9A 1HR0H 4JV5H 3OTOH 4G08A 4FJUA 3QD7X 4B8CD 4NXNH 4DV0H 4GKKH 4DV2H 3J80W 4LF5H 4KHPH 2CTLA 4LFAH 1WTJA 3T1YH 4B3RH 1PQXA 2D9IA 4K0KH 1X9ZA 3V69A 4YHHH 2ANRA 1X0AA 2CWHA 4X64H 5C0XG 4DV5H 2O4CA 2UXDH 2JZXA 5BR8H 2K1HA 2UXCH 3SB1A 3GR5A 4JVYA 4NBQA 1N36H 4OO1G 4E9JA 2ANNA 2HH2A 4JI6H 4OD6A 1Z2IA 4DR3H 1I6UA 2VQFH 3VKEA 2CTFA 5FLXW 2JE6I 4DR5H 1FKAH 2PT7G 4JI8H 4PDBA 3GKUA 4NXMH 5K36G 4JI2H 4DV1H 2CWFA 1AN7A 1WHRA 3KDGA 4JYAH 1ZZJA 4NZRM 2CTKA 3FAUA 2LTLA 1IBKH 1DTJA 1EC6A 4NZTM 4H8AA 2NN6G 2LTMA 2YQRA 2FPHX 4IFDG 2ZQEA 5LMNH 4DR4H 4YY3H 3GABA 4DR1H 2OPUA 1J5EH 2AXYA 1S03G 1XNRH 2G8YA 2F4VH 4LF6H 2Y3MA 1TUAA 4JI4H 1HNXH 4DR6H 2Z0SA 1MSZA 1HNZH 1N34H 4B3SH 1XMOH 3I0PA 2PY9A 1XNQH 2CTJA 4LF8H 1I94H 4LFCH 4FJSA 1XRHA 4AQYH 2E5LH 4B3MH 2UXBH 1F0XA 2FFMA 4JI0H 2JEAI 3OSSD 2CPMA 2UU9H 5LMUH 2OPVA 2FMRA 3L7ZC 3KDKA 2JA9A 1J5KA 2HHHH 2JVZA 3U1KA 4DV7H 1IBMH 4DR7H 2P2RA 4QMFB 1WE8A 3AEVB 1ZZIA 1VBIA 4JI3H 2M8WA 5JEAG 5IWAH 4DUYH 4JI5H 4LF4H 4WANA 1X4MA 4B3TH 1NXUA 1ODHA 4BA2I 2LF0A 1WVNA 2CTEA 1ZTGA 4OCHA 2HH3A 4EC5A 3T1HH 4JI7H 4DUZH 2A1SA 4DR2H 1SEIA 3UOEA 5A2QW 2VQEH 4DV6H 4WALA 4B8TA 3RF2A 4DV4H 2PQUA 4LF9H 1ZZKA 4LIJA 4X66H 4LFBH 2ZM6H 1K1GA 1X4NA 1N32H 2BA0A 2BL5A 2X06A 1FJGH 1IBLH 1DT4A 2QNDA 2DGRA 5IT9W 2CTMA 2JEBI 1N33H 3J81W 4AIMA 2UUBH 3NCVA 5LL6b 2VKCA
chains in the Genus database with same CATH topology
5JEAG 2JZXA 4WANA 4JVYA 1X4MA 1TUAA 4NBQA 4OO1G 2Z0SA 2E3UA 2ANNA 2HH2A 1WVNA 2CPQA 2CTEA 1ZTGA 4BA2I 3VKEA 1KHMA 2CTFA 2HH3A 2JE6I 2PY9A 2CTJA 5K36G 4BA1I 2MJHA 4WALA 4B8TA 1VIHA 1J4WA 2PQUA 1ZZKA 1ZZJA 4LIJA 2JEAI 3AEVB 4AM3A 2CTKA 4JVHA 1K1GA 1X4NA 1VIGA 2OPVA 2BA0A 1DTJA 2BL5A 1EC6A 1DT4A 2FMRA 2NN6G 3L7ZC 2ANRA 2JA9A 2DGRA 2QNDA 2CTMA 2JEBI 2YQRA 1J5KA 2JVZA 2CTLA 4IFDG 3U1KA 3V69A 4AIMA 2P2RA 4QMFB 1WE8A 2OPUA 5C0XG 2AXYA 1ZZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JEA G;  2JZX A;  4WAN A;  4JVY A;  1X4M A;  1TUA A;  4NBQ A;  4OO1 G;  2Z0S A;  2E3U A;  2ANN A;  2HH2 A;  1WVN A;  2CPQ A;  2CTE A;  1ZTG A;  4BA2 I;  3VKE A;  1KHM A;  2CTF A;  2HH3 A;  2JE6 I;  2PY9 A;  2CTJ A;  5K36 G;  4BA1 I;  2MJH A;  4WAL A;  4B8T A;  1VIH A;  1J4W A;  2PQU A;  1ZZK A;  1ZZJ A;  4LIJ A;  2JEA I;  3AEV B;  4AM3 A;  2CTK A;  4JVH A;  1K1G A;  1X4N A;  1VIG A;  2OPV A;  2BA0 A;  1DTJ A;  2BL5 A;  1EC6 A;  1DT4 A;  2FMR A;  2NN6 G;  3L7Z C;  2ANR A;  2JA9 A;  2DGR A;  2QND A;  2CTM A;  2JEB I;  2YQR A;  1J5K A;  2JVZ A;  2CTL A;  4IFD G;  3U1K A;  3V69 A;  4AIM A;  2P2R A;  4QMF B;  1WE8 A;  2OPU A;  5C0X G;  2AXY A;  1ZZI A; 
#chains in the Genus database with same CATH topology
 1V8C A;  2UUC H;  1V9N A;  2UUA H;  2E3U A;  3J7A K;  2CPQ A;  1UG8 A;  3JAM W;  1KHM A;  4X62 H;  1XMQ H;  4LF7 H;  4JI1 H;  4BA1 I;  2MJH A;  2LRR A;  4OX9 H;  1J4W A;  1VIH A;  3OET A;  4GKJ H;  4X65 H;  4AM3 A;  4JVH A;  1HNW H;  1S20 A;  3EZJ A;  4DV3 H;  1VIG A;  2M6Q A;  5DT9 A;  1HR0 H;  4JV5 H;  3OTO H;  4G08 A;  4FJU A;  3QD7 X;  4B8C D;  4NXN H;  4DV0 H;  4GKK H;  4DV2 H;  3J80 W;  4LF5 H;  4KHP H;  2CTL A;  4LFA H;  1WTJ A;  3T1Y H;  4B3R H;  1PQX A;  2D9I A;  4K0K H;  1X9Z A;  3V69 A;  4YHH H;  2ANR A;  1X0A A;  2CWH A;  4X64 H;  5C0X G;  4DV5 H;  2O4C A;  2UXD H;  2JZX A;  5BR8 H;  2K1H A;  2UXC H;  3SB1 A;  3GR5 A;  4JVY A;  4NBQ A;  1N36 H;  4OO1 G;  4E9J A;  2ANN A;  2HH2 A;  4JI6 H;  4OD6 A;  1Z2I A;  4DR3 H;  1I6U A;  2VQF H;  3VKE A;  2CTF A;  5FLX W;  2JE6 I;  4DR5 H;  1FKA H;  2PT7 G;  4JI8 H;  4PDB A;  3GKU A;  4NXM H;  5K36 G;  4JI2 H;  4DV1 H;  2CWF A;  1AN7 A;  1WHR A;  3KDG A;  4JYA H;  1ZZJ A;  4NZR M;  2CTK A;  3FAU A;  2LTL A;  1IBK H;  1DTJ A;  1EC6 A;  4NZT M;  4H8A A;  2NN6 G;  2LTM A;  2YQR A;  2FPH X;  4IFD G;  2ZQE A;  5LMN H;  4DR4 H;  4YY3 H;  3GAB A;  4DR1 H;  2OPU A;  1J5E H;  2AXY A;  1S03 G;  1XNR H;  2G8Y A;  2F4V H;  4LF6 H;  2Y3M A;  1TUA A;  4JI4 H;  1HNX H;  4DR6 H;  2Z0S A;  1MSZ A;  1HNZ H;  1N34 H;  4B3S H;  1XMO H;  3I0P A;  2PY9 A;  1XNQ H;  2CTJ A;  4LF8 H;  1I94 H;  4LFC H;  4FJS A;  1XRH A;  4AQY H;  2E5L H;  4B3M H;  2UXB H;  1F0X A;  2FFM A;  4JI0 H;  2JEA I;  3OSS D;  2CPM A;  2UU9 H;  5LMU H;  2OPV A;  2FMR A;  3L7Z C;  3KDK A;  2JA9 A;  1J5K A;  2HHH H;  2JVZ A;  3U1K A;  4DV7 H;  1IBM H;  4DR7 H;  2P2R A;  4QMF B;  1WE8 A;  3AEV B;  1ZZI A;  1VBI A;  4JI3 H;  2M8W A;  5JEA G;  5IWA H;  4DUY H;  4JI5 H;  4LF4 H;  4WAN A;  1X4M A;  4B3T H;  1NXU A;  1ODH A;  4BA2 I;  2LF0 A;  1WVN A;  2CTE A;  1ZTG A;  4OCH A;  2HH3 A;  4EC5 A;  3T1H H;  4JI7 H;  4DUZ H;  2A1S A;  4DR2 H;  1SEI A;  3UOE A;  5A2Q W;  2VQE H;  4DV6 H;  4WAL A;  4B8T A;  3RF2 A;  4DV4 H;  2PQU A;  4LF9 H;  1ZZK A;  4LIJ A;  4X66 H;  4LFB H;  2ZM6 H;  1K1G A;  1X4N A;  1N32 H;  2BA0 A;  2BL5 A;  2X06 A;  1FJG H;  1IBL H;  1DT4 A;  2QND A;  2DGR A;  5IT9 W;  2CTM A;  2JEB I;  1N33 H;  3J81 W;  4AIM A;  2UUB H;  3NCV A;  5LL6 b;  2VKC A; 
#chains in the Genus database with same CATH homology
 5JEA G;  2JZX A;  4WAN A;  4JVY A;  1X4M A;  1TUA A;  4NBQ A;  4OO1 G;  2Z0S A;  2E3U A;  2ANN A;  2HH2 A;  1WVN A;  2CPQ A;  2CTE A;  1ZTG A;  4BA2 I;  3VKE A;  1KHM A;  2CTF A;  2HH3 A;  2JE6 I;  2PY9 A;  2CTJ A;  5K36 G;  4BA1 I;  2MJH A;  4WAL A;  4B8T A;  1VIH A;  1J4W A;  2PQU A;  1ZZK A;  1ZZJ A;  4LIJ A;  2JEA I;  3AEV B;  4AM3 A;  2CTK A;  4JVH A;  1K1G A;  1X4N A;  1VIG A;  2OPV A;  2BA0 A;  1DTJ A;  2BL5 A;  1EC6 A;  1DT4 A;  2FMR A;  2NN6 G;  3L7Z C;  2ANR A;  2JA9 A;  2DGR A;  2QND A;  2CTM A;  2JEB I;  2YQR A;  1J5K A;  2JVZ A;  2CTL A;  4IFD G;  3U1K A;  3V69 A;  4AIM A;  2P2R A;  4QMF B;  1WE8 A;  2OPU A;  5C0X G;  2AXY A;  1ZZI A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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