2HH2 | Genus

Total Genus 18

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	18
sequence length	79
structure length	79
Chain Sequence	GEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Rna binding protein
source organism	Homo sapiens
publication title	The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation. pubmed doi rcsb
molecule keywords	KH-type splicing regulatory protein
total genus	18
structure length	79
sequence length	79
ec nomenclature
pdb deposition date	2006-06-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00013	KH_1	KH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1370.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S8; Chain: A, domain 1	K Homology domain, type 1	2hh2A00

2CTFA 4NBQA 1TUAA 2HH3A 2JEAI 4BA2I 2YQRA 4IFDG 2AXYA 1WVNA 2BL5A 4B8TA 1J4WA 2CPQA 2ANNA 2CTMA 2JVZA 3V69A 2PY9A 4AM3A 2P2RA 4OO1G 2JA9A 4WANA 2HH2A 1ZZJA 1KHMA 1ZZKA 2JZXA 2MJHA 2BA0A 2OPUA 2OPVA 1X4MA 1K1GA 2ANRA 3AEVB 4BA1I 4WALA 5C0XG 2JEBI 1EC6A 2CTJA 1ZZIA 4QMFB 2NN6G 2JE6I 2FMRA 2Z0SA 1J5KA 2E3UA 4LIJA 2CTKA 4JVHA 1X4NA 1DT4A 1WE8A 3VKEA 1DTJA 2PQUA 5K36G 1VIGA 2DGRA 4JVYA 2CTLA 4AIMA 3L7ZC 1ZTGA 1VIHA 2QNDA 5JEAG 2CTEA 3U1KA
chains in the Genus database with same CATH superfamily

4BA2I 4DV0H 1V9NA 1SEIA 2CPQA 4DR6H 1XMQH 1V8CA 4AQYH 3JAMW 4K0KH 1WTJA 1ZZKA 4JI8H 2X06A 4NXMH 2BA0A 4E9JA 4G08A 4DV6H 2ANRA 2UXDH 4JI4H 3AEVB 2O4CA 4BA1I 2CTJA 4NZRM 1S20A 4QMFB 2VQFH 4LF5H 4B8CD 1HNZH 4DR4H 4FJUA 4X66H 2Z0SA 4YY3H 4B3MH 4NZTM 3GKUA 2CPMA 2E3UA 1J5KA 1HNWH 4LIJA 3UOEA 1N32H 1N36H 1X4NA 3VKEA 4JVHA 4DV4H 3I0PA 2HHHH 2LTLA 4AIMA 2LRRA 2G8YA 1HR0H 4JVYA 2UXBH 5FLXW 5LMUH 2UUBH 4JV5H 1TUAA 4B3RH 2UUCH 4OX9H 4H8AA 1WVNA 2K1HA 2CWFA 4DR3H 3J80W 3V69A 2PY9A 4OO1G 4GKKH 4KHPH 2JA9A 4WANA 4X65H 3KDGA 2MJHA 2JZXA 2D9IA 1K1GA 3GABA 1FKAH 4JI5H 3J7AK 3OETA 4YHHH 1IBKH 2UXCH 1XNQH 1N33H 4DV2H 1ZZIA 1WHRA 2M8WA 4PDBA 1XNRH 1I94H 4DV1H 1F0XA 1ODHA 2CTKA 4DR5H 2PQUA 1DTJA 2DGRA 2Y3MA 3L7ZC 2E5LH 2CTEA 3U1KA 2CTFA 4NBQA 1N34H 4B3SH 5A2QW 2YQRA 3QD7X 3SB1A 1XRHA 2AXYA 1J4WA 3J81W 3OSSD 4X62H 4JI7H 2JVZA 4AM3A 1VBIA 5IWAH 2HH2A 1ZZJA 3T1HH 4DR1H 4LF6H 1NXUA 2OPUA 2OPVA 4WALA 2JEBI 2CWHA 2FPHX 4NXNH 1X0AA 4DR2H 1PQXA 5LL6b 2JE6I 4OD6A 4JI2H 1J5EH 4DV3H 2ZQEA 2F4VH 2VQEH 1MSZA 4JYAH 1WE8A 1VIGA 2FFMA 4EC5A 4LF8H 4LFCH 1VIHA 2QNDA 4X64H 5JEAG 1IBLH 2UU9H 1S03G 1X9ZA 3KDKA 5IT9W 1EC6A 2HH3A 4LFAH 4JI0H 2JEAI 4IFDG 4GKJH 2BL5A 4B8TA 2ANNA 1AN7A 2CTMA 1Z2IA 5LMNH 4LFBH 2P2RA 1XMOH 2LF0A 1KHMA 4B3TH 1X4MA 4DR7H 4OCHA 3GR5A 5C0XG 5DT9A 2VKCA 2LTMA 4JI1H 2NN6G 1I6UA 4DUYH 1FJGH 1HNXH 3FAUA 4DV7H 2FMRA 2M6QA 2ZM6H 4DV5H 4LF4H 4JI3H 4DUZH 5BR8H 1IBMH 1DT4A 3NCVA 4FJSA 4LF7H 1UG8A 3RF2A 5K36G 2A1SA 3OTOH 2CTLA 1ZTGA 3EZJA 4JI6H 3T1YH 4LF9H 2UUAH 2PT7G
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2CTF A;  4NBQ A;  1TUA A;  2HH3 A;  2JEA I;  4BA2 I;  2YQR A;  4IFD G;  2AXY A;  1WVN A;  2BL5 A;  4B8T A;  1J4W A;  2CPQ A;  2ANN A;  2CTM A;  2JVZ A;  3V69 A;  2PY9 A;  4AM3 A;  2P2R A;  4OO1 G;  2JA9 A;  4WAN A;  2HH2 A;  1ZZJ A;  1KHM A;  1ZZK A;  2JZX A;  2MJH A;  2BA0 A;  2OPU A;  2OPV A;  1X4M A;  1K1G A;  2ANR A;  3AEV B;  4BA1 I;  4WAL A;  5C0X G;  2JEB I;  1EC6 A;  2CTJ A;  1ZZI A;  4QMF B;  2NN6 G;  2JE6 I;  2FMR A;  2Z0S A;  1J5K A;  2E3U A;  4LIJ A;  2CTK A;  4JVH A;  1X4N A;  1DT4 A;  1WE8 A;  3VKE A;  1DTJ A;  2PQU A;  5K36 G;  1VIG A;  2DGR A;  4JVY A;  2CTL A;  4AIM A;  3L7Z C;  1ZTG A;  1VIH A;  2QND A;  5JEA G;  2CTE A;  3U1K A; 
#chains in the Genus database with same CATH topology
 4BA2 I;  4DV0 H;  1V9N A;  1SEI A;  2CPQ A;  4DR6 H;  1XMQ H;  1V8C A;  4AQY H;  3JAM W;  4K0K H;  1WTJ A;  1ZZK A;  4JI8 H;  2X06 A;  4NXM H;  2BA0 A;  4E9J A;  4G08 A;  4DV6 H;  2ANR A;  2UXD H;  4JI4 H;  3AEV B;  2O4C A;  4BA1 I;  2CTJ A;  4NZR M;  1S20 A;  4QMF B;  2VQF H;  4LF5 H;  4B8C D;  1HNZ H;  4DR4 H;  4FJU A;  4X66 H;  2Z0S A;  4YY3 H;  4B3M H;  4NZT M;  3GKU A;  2CPM A;  2E3U A;  1J5K A;  1HNW H;  4LIJ A;  3UOE A;  1N32 H;  1N36 H;  1X4N A;  3VKE A;  4JVH A;  4DV4 H;  3I0P A;  2HHH H;  2LTL A;  4AIM A;  2LRR A;  2G8Y A;  1HR0 H;  4JVY A;  2UXB H;  5FLX W;  5LMU H;  2UUB H;  4JV5 H;  1TUA A;  4B3R H;  2UUC H;  4OX9 H;  4H8A A;  1WVN A;  2K1H A;  2CWF A;  4DR3 H;  3J80 W;  3V69 A;  2PY9 A;  4OO1 G;  4GKK H;  4KHP H;  2JA9 A;  4WAN A;  4X65 H;  3KDG A;  2MJH A;  2JZX A;  2D9I A;  1K1G A;  3GAB A;  1FKA H;  4JI5 H;  3J7A K;  3OET A;  4YHH H;  1IBK H;  2UXC H;  1XNQ H;  1N33 H;  4DV2 H;  1ZZI A;  1WHR A;  2M8W A;  4PDB A;  1XNR H;  1I94 H;  4DV1 H;  1F0X A;  1ODH A;  2CTK A;  4DR5 H;  2PQU A;  1DTJ A;  2DGR A;  2Y3M A;  3L7Z C;  2E5L H;  2CTE A;  3U1K A;  2CTF A;  4NBQ A;  1N34 H;  4B3S H;  5A2Q W;  2YQR A;  3QD7 X;  3SB1 A;  1XRH A;  2AXY A;  1J4W A;  3J81 W;  3OSS D;  4X62 H;  4JI7 H;  2JVZ A;  4AM3 A;  1VBI A;  5IWA H;  2HH2 A;  1ZZJ A;  3T1H H;  4DR1 H;  4LF6 H;  1NXU A;  2OPU A;  2OPV A;  4WAL A;  2JEB I;  2CWH A;  2FPH X;  4NXN H;  1X0A A;  4DR2 H;  1PQX A;  5LL6 b;  2JE6 I;  4OD6 A;  4JI2 H;  1J5E H;  4DV3 H;  2ZQE A;  2F4V H;  2VQE H;  1MSZ A;  4JYA H;  1WE8 A;  1VIG A;  2FFM A;  4EC5 A;  4LF8 H;  4LFC H;  1VIH A;  2QND A;  4X64 H;  5JEA G;  1IBL H;  2UU9 H;  1S03 G;  1X9Z A;  3KDK A;  5IT9 W;  1EC6 A;  2HH3 A;  4LFA H;  4JI0 H;  2JEA I;  4IFD G;  4GKJ H;  2BL5 A;  4B8T A;  2ANN A;  1AN7 A;  2CTM A;  1Z2I A;  5LMN H;  4LFB H;  2P2R A;  1XMO H;  2LF0 A;  1KHM A;  4B3T H;  1X4M A;  4DR7 H;  4OCH A;  3GR5 A;  5C0X G;  5DT9 A;  2VKC A;  2LTM A;  4JI1 H;  2NN6 G;  1I6U A;  4DUY H;  1FJG H;  1HNX H;  3FAU A;  4DV7 H;  2FMR A;  2M6Q A;  2ZM6 H;  4DV5 H;  4LF4 H;  4JI3 H;  4DUZ H;  5BR8 H;  1IBM H;  1DT4 A;  3NCV A;  4FJS A;  4LF7 H;  1UG8 A;  3RF2 A;  5K36 G;  2A1S A;  3OTO H;  2CTL A;  1ZTG A;  3EZJ A;  4JI6 H;  3T1Y H;  4LF9 H;  2UUA H;  2PT7 G; 
#chains in the Genus database with same CATH homology
 2CTF A;  4NBQ A;  1TUA A;  2HH3 A;  2JEA I;  4BA2 I;  2YQR A;  4IFD G;  2AXY A;  1WVN A;  2BL5 A;  4B8T A;  1J4W A;  2CPQ A;  2ANN A;  2CTM A;  2JVZ A;  3V69 A;  2PY9 A;  4AM3 A;  2P2R A;  4OO1 G;  2JA9 A;  4WAN A;  2HH2 A;  1ZZJ A;  1KHM A;  1ZZK A;  2JZX A;  2MJH A;  2BA0 A;  2OPU A;  2OPV A;  1X4M A;  1K1G A;  2ANR A;  3AEV B;  4BA1 I;  4WAL A;  5C0X G;  2JEB I;  1EC6 A;  2CTJ A;  1ZZI A;  4QMF B;  2NN6 G;  2JE6 I;  2FMR A;  2Z0S A;  1J5K A;  2E3U A;  4LIJ A;  2CTK A;  4JVH A;  1X4N A;  1DT4 A;  1WE8 A;  3VKE A;  1DTJ A;  2PQU A;  5K36 G;  1VIG A;  2DGR A;  4JVY A;  2CTL A;  4AIM A;  3L7Z C;  1ZTG A;  1VIH A;  2QND A;  5JEA G;  2CTE A;  3U1K A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2HH2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations