2HH3A

Solution structure of the third kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
71
structure length
71
Chain Sequence
GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Rna binding protein
source organism Homo sapiens
publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh3A00
2CTLA 2FMRA 2JEAI 1X4NA 1J5KA 2OPUA 2MJHA 5K36G 2NN6G 2YQRA 2CTJA 1X4MA 2CTEA 1J4WA 1TUAA 1KHMA 4NBQA 4OO1G 3VKEA 1WVNA 1K1GA 4JVYA 2PY9A 4WANA 5C0XG 2JZXA 4AIMA 2CTKA 2ANNA 2QNDA 4JVHA 3V69A 2CTFA 1ZZKA 1ZZJA 2E3UA 2JVZA 2CPQA 2Z0SA 2AXYA 4IFDG 2CTMA 1WE8A 2HH2A 1DTJA 3U1KA 2ANRA 4QMFB 4BA1I 1ZTGA 2P2RA 3AEVB 2DGRA 1DT4A 2BL5A 2JEBI 3L7ZC 4BA2I 4LIJA 1VIGA 2JA9A 2HH3A 4AM3A 5JEAG 1VIHA 4B8TA 1ZZIA 2PQUA 2BA0A 2JE6I 2OPVA 1EC6A 4WALA
chains in the Genus database with same CATH superfamily
4JI6H 2JEAI 1S20A 1PQXA 2ZQEA 1I94H 1V9NA 4DUYH 5K36G 2NN6G 2CTEA 4LF5H 3QD7X 4KHPH 1N33H 4NBQA 1KHMA 5IT9W 4B3RH 1WVNA 4DUZH 2PY9A 2CPMA 2QNDA 2UUCH 1XNQH 2LTLA 5A2QW 1IBLH 1IBKH 2HHHH 4LFBH 2E3UA 2VKCA 5IWAH 3NCVA 2AXYA 1HR0H 1X9ZA 1WE8A 3J7AK 5LMUH 3AEVB 2VQEH 3UOEA 4LF8H 2UUAH 3L7ZC 4DV1H 3KDGA 4LIJA 3EZJA 1WHRA 4X62H 2ZM6H 2Y3MA 1VIGA 4NXMH 2PQUA 4NZTM 1V8CA 2FMRA 2OPUA 1N36H 4OX9H 2FFMA 4DR5H 1I6UA 2CTJA 1HNXH 2LF0A 1J4WA 2UUBH 4DR4H 2UXBH 3T1HH 2JZXA 4DR3H 2ANNA 4DV3H 4YY3H 1WTJA 3RF2A 4OD6A 4LF4H 1ZZKA 4B8CD 1XMOH 4JV5H 4G08A 2Z0SA 1HNZH 4JI0H 2CTMA 2ANRA 1DTJA 3U1KA 2P2RA 4QMFB 1NXUA 2BL5A 3J80W 4LFAH 2CWHA 4NXNH 4AQYH 2M6QA 4YHHH 4JI8H 4BA2I 3GABA 1XRHA 4NZRM 4X64H 1MSZA 2HH3A 5JEAG 1VIHA 4B8TA 2LRRA 4K0KH 1XNRH 1EC6A 1XMQH 4DV4H 1J5KA 4FJSA 4DV7H 1IBMH 4DR6H 2YQRA 1UG8A 1FKAH 4X66H 4DV0H 1TUAA 2D9IA 4B3SH 4OO1G 5C0XG 4JVHA 2CTKA 4JI1H 3V69A 2CTFA 5FLXW 4JI2H 2M8WA 4B3TH 2JVZA 2O4CA 4IFDG 3OSSD 3KDKA 4PDBA 4JI7H 4BA1I 1ZTGA 4GKKH 2DGRA 1Z2IA 1DT4A 3GR5A 2JEBI 1S03G 1J5EH 2UXCH 4B3MH 4OCHA 4DV2H 2F4VH 4AM3A 2FPHX 2CWFA 2JE6I 3FAUA 2A1SA 2OPVA 1AN7A 4E9JA 4WALA 2CTLA 4FJUA 2UU9H 1X4NA 3T1YH 4LF7H 2MJHA 1SEIA 4LF9H 3OETA 4DV6H 4LFCH 1X4MA 5LMNH 4GKJH 2G8YA 4JYAH 2VQFH 4LF6H 3VKEA 1K1GA 1ODHA 2E5LH 4DR2H 4JVYA 4WANA 4AIMA 1FJGH 5BR8H 4X65H 5LL6b 1HNWH 2UXDH 3SB1A 1ZZJA 2LTMA 3J81W 2CPQA 4EC5A 4JI3H 2HH2A 2X06A 3OTOH 3JAMW 3I0PA 1F0XA 1N34H 5DT9A 4DR1H 2K1HA 4JI4H 2PT7G 4H8AA 2JA9A 4DV5H 1VBIA 1N32H 1ZZIA 4DR7H 2BA0A 3GKUA 4JI5H 1X0AA
chains in the Genus database with same CATH topology
2CTLA 2FMRA 2JEAI 1X4NA 1J5KA 2OPUA 2MJHA 5K36G 2NN6G 2YQRA 2CTJA 1X4MA 2CTEA 1J4WA 1TUAA 1KHMA 4NBQA 4OO1G 3VKEA 1WVNA 1K1GA 4JVYA 2PY9A 4WANA 5C0XG 2JZXA 4AIMA 2CTKA 2ANNA 2QNDA 4JVHA 3V69A 2CTFA 1ZZKA 1ZZJA 2E3UA 2JVZA 2CPQA 2Z0SA 2AXYA 4IFDG 2CTMA 1WE8A 2HH2A 1DTJA 3U1KA 2ANRA 4QMFB 4BA1I 1ZTGA 2P2RA 3AEVB 2DGRA 1DT4A 2BL5A 2JEBI 3L7ZC 4BA2I 4LIJA 1VIGA 2JA9A 2HH3A 4AM3A 5JEAG 1VIHA 4B8TA 1ZZIA 2PQUA 2BA0A 2JE6I 2OPVA 1EC6A 4WALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CTL A;  2FMR A;  2JEA I;  1X4N A;  1J5K A;  2OPU A;  2MJH A;  5K36 G;  2NN6 G;  2YQR A;  2CTJ A;  1X4M A;  2CTE A;  1J4W A;  1TUA A;  1KHM A;  4NBQ A;  4OO1 G;  3VKE A;  1WVN A;  1K1G A;  4JVY A;  2PY9 A;  4WAN A;  5C0X G;  2JZX A;  4AIM A;  2CTK A;  2ANN A;  2QND A;  4JVH A;  3V69 A;  2CTF A;  1ZZK A;  1ZZJ A;  2E3U A;  2JVZ A;  2CPQ A;  2Z0S A;  2AXY A;  4IFD G;  2CTM A;  1WE8 A;  2HH2 A;  1DTJ A;  3U1K A;  2ANR A;  4QMF B;  4BA1 I;  1ZTG A;  2P2R A;  3AEV B;  2DGR A;  1DT4 A;  2BL5 A;  2JEB I;  3L7Z C;  4BA2 I;  4LIJ A;  1VIG A;  2JA9 A;  2HH3 A;  4AM3 A;  5JEA G;  1VIH A;  4B8T A;  1ZZI A;  2PQU A;  2BA0 A;  2JE6 I;  2OPV A;  1EC6 A;  4WAL A; 
#chains in the Genus database with same CATH topology
 4JI6 H;  2JEA I;  1S20 A;  1PQX A;  2ZQE A;  1I94 H;  1V9N A;  4DUY H;  5K36 G;  2NN6 G;  2CTE A;  4LF5 H;  3QD7 X;  4KHP H;  1N33 H;  4NBQ A;  1KHM A;  5IT9 W;  4B3R H;  1WVN A;  4DUZ H;  2PY9 A;  2CPM A;  2QND A;  2UUC H;  1XNQ H;  2LTL A;  5A2Q W;  1IBL H;  1IBK H;  2HHH H;  4LFB H;  2E3U A;  2VKC A;  5IWA H;  3NCV A;  2AXY A;  1HR0 H;  1X9Z A;  1WE8 A;  3J7A K;  5LMU H;  3AEV B;  2VQE H;  3UOE A;  4LF8 H;  2UUA H;  3L7Z C;  4DV1 H;  3KDG A;  4LIJ A;  3EZJ A;  1WHR A;  4X62 H;  2ZM6 H;  2Y3M A;  1VIG A;  4NXM H;  2PQU A;  4NZT M;  1V8C A;  2FMR A;  2OPU A;  1N36 H;  4OX9 H;  2FFM A;  4DR5 H;  1I6U A;  2CTJ A;  1HNX H;  2LF0 A;  1J4W A;  2UUB H;  4DR4 H;  2UXB H;  3T1H H;  2JZX A;  4DR3 H;  2ANN A;  4DV3 H;  4YY3 H;  1WTJ A;  3RF2 A;  4OD6 A;  4LF4 H;  1ZZK A;  4B8C D;  1XMO H;  4JV5 H;  4G08 A;  2Z0S A;  1HNZ H;  4JI0 H;  2CTM A;  2ANR A;  1DTJ A;  3U1K A;  2P2R A;  4QMF B;  1NXU A;  2BL5 A;  3J80 W;  4LFA H;  2CWH A;  4NXN H;  4AQY H;  2M6Q A;  4YHH H;  4JI8 H;  4BA2 I;  3GAB A;  1XRH A;  4NZR M;  4X64 H;  1MSZ A;  2HH3 A;  5JEA G;  1VIH A;  4B8T A;  2LRR A;  4K0K H;  1XNR H;  1EC6 A;  1XMQ H;  4DV4 H;  1J5K A;  4FJS A;  4DV7 H;  1IBM H;  4DR6 H;  2YQR A;  1UG8 A;  1FKA H;  4X66 H;  4DV0 H;  1TUA A;  2D9I A;  4B3S H;  4OO1 G;  5C0X G;  4JVH A;  2CTK A;  4JI1 H;  3V69 A;  2CTF A;  5FLX W;  4JI2 H;  2M8W A;  4B3T H;  2JVZ A;  2O4C A;  4IFD G;  3OSS D;  3KDK A;  4PDB A;  4JI7 H;  4BA1 I;  1ZTG A;  4GKK H;  2DGR A;  1Z2I A;  1DT4 A;  3GR5 A;  2JEB I;  1S03 G;  1J5E H;  2UXC H;  4B3M H;  4OCH A;  4DV2 H;  2F4V H;  4AM3 A;  2FPH X;  2CWF A;  2JE6 I;  3FAU A;  2A1S A;  2OPV A;  1AN7 A;  4E9J A;  4WAL A;  2CTL A;  4FJU A;  2UU9 H;  1X4N A;  3T1Y H;  4LF7 H;  2MJH A;  1SEI A;  4LF9 H;  3OET A;  4DV6 H;  4LFC H;  1X4M A;  5LMN H;  4GKJ H;  2G8Y A;  4JYA H;  2VQF H;  4LF6 H;  3VKE A;  1K1G A;  1ODH A;  2E5L H;  4DR2 H;  4JVY A;  4WAN A;  4AIM A;  1FJG H;  5BR8 H;  4X65 H;  5LL6 b;  1HNW H;  2UXD H;  3SB1 A;  1ZZJ A;  2LTM A;  3J81 W;  2CPQ A;  4EC5 A;  4JI3 H;  2HH2 A;  2X06 A;  3OTO H;  3JAM W;  3I0P A;  1F0X A;  1N34 H;  5DT9 A;  4DR1 H;  2K1H A;  4JI4 H;  2PT7 G;  4H8A A;  2JA9 A;  4DV5 H;  1VBI A;  1N32 H;  1ZZI A;  4DR7 H;  2BA0 A;  3GKU A;  4JI5 H;  1X0A A; 
#chains in the Genus database with same CATH homology
 2CTL A;  2FMR A;  2JEA I;  1X4N A;  1J5K A;  2OPU A;  2MJH A;  5K36 G;  2NN6 G;  2YQR A;  2CTJ A;  1X4M A;  2CTE A;  1J4W A;  1TUA A;  1KHM A;  4NBQ A;  4OO1 G;  3VKE A;  1WVN A;  1K1G A;  4JVY A;  2PY9 A;  4WAN A;  5C0X G;  2JZX A;  4AIM A;  2CTK A;  2ANN A;  2QND A;  4JVH A;  3V69 A;  2CTF A;  1ZZK A;  1ZZJ A;  2E3U A;  2JVZ A;  2CPQ A;  2Z0S A;  2AXY A;  4IFD G;  2CTM A;  1WE8 A;  2HH2 A;  1DTJ A;  3U1K A;  2ANR A;  4QMF B;  4BA1 I;  1ZTG A;  2P2R A;  3AEV B;  2DGR A;  1DT4 A;  2BL5 A;  2JEB I;  3L7Z C;  4BA2 I;  4LIJ A;  1VIG A;  2JA9 A;  2HH3 A;  4AM3 A;  5JEA G;  1VIH A;  4B8T A;  1ZZI A;  2PQU A;  2BA0 A;  2JE6 I;  2OPV A;  1EC6 A;  4WAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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