2HH3A

Solution structure of the third kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
71
structure length
71
Chain Sequence
GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh3A00
4AIMA 1DTJA 2FMRA 3V69A 4B8TA 2CTMA 4JVYA 4BA2I 2NN6G 1K1GA 2CTLA 3AEVB 4NBQA 1TUAA 1WVNA 2OPUA 4LIJA 1VIHA 2CTFA 2CTJA 2CPQA 4WALA 1ZTGA 2MJHA 2JVZA 2PQUA 4OO1G 5K36G 2BA0A 2QNDA 4AM3A 3U1KA 5JEAG 2ANNA 4BA1I 1X4MA 2JE6I 2AXYA 2HH2A 1ZZJA 2CTKA 2PY9A 1KHMA 2P2RA 2JA9A 1J4WA 2DGRA 1WE8A 2BL5A 3L7ZC 4JVHA 2CTEA 1EC6A 2HH3A 2OPVA 4QMFB 1ZZKA 4IFDG 4WANA 2YQRA 1ZZIA 1J5KA 2ANRA 3VKEA 1X4NA 2E3UA 2JEBI 2JZXA 1VIGA 5C0XG 2JEAI 2Z0SA 1DT4A
chains in the Genus database with same CATH superfamily
4B8CD 2FPHX 3SB1A 3T1YH 4LFCH 2CTMA 4OX9H 4YHHH 1FKAH 2CTLA 2D9IA 4NZTM 4JI1H 1WVNA 4EC5A 2A1SA 4B3RH 2MJHA 4DV0H 1ZTGA 4B3TH 2JVZA 3T1HH 5LL6b 1S20A 5IT9W 2M6QA 4JI3H 4BA1I 1X4MA 4LF8H 2PY9A 1ZZJA 5BR8H 1HR0H 4NXMH 4K0KH 3JAMW 4NZRM 1NXUA 2ZM6H 3L7ZC 1XMOH 4QMFB 5A2QW 2ZQEA 4LFAH 4DV1H 4LF9H 4JV5H 3VKEA 2E3UA 4DR3H 4GKJH 4JVYA 4JI2H 2Z0SA 2F4VH 1XMQH 1DTJA 1XNRH 1IBLH 4JI6H 4G08A 3V69A 4B8TA 1J5EH 1PQXA 4JI5H 2CWFA 1I6UA 1TUAA 2UUCH 2CWHA 1V8CA 4X62H 2VQFH 1XRHA 5IWAH 4WALA 4DR2H 3J80W 3OSSD 2PQUA 4YY3H 4AM3A 2ANNA 2CPMA 2JE6I 2LTLA 1ODHA 4NXNH 2LF0A 1VBIA 1AN7A 4DV2H 4DR1H 1WTJA 3GABA 3J81W 2OPVA 1S03G 4IFDG 2UXBH 3QD7X 2YQRA 1ZZIA 1J5KA 4JI7H 1V9NA 4OCHA 2O4CA 5LMNH 1Z2IA 2E5LH 4JI0H 2JZXA 2VKCA 4DUZH 4DV3H 5LMUH 1I94H 4BA2I 2FFMA 4DR4H 1F0XA 1N34H 4LF5H 1FJGH 4LIJA 2VQEH 1VIHA 4DR5H 2UUAH 1UG8A 4KHPH 1XNQH 1HNWH 4DR6H 4DV6H 4H8AA 1IBKH 2BA0A 4OO1G 4X64H 2LTMA 3U1KA 3NCVA 1HNXH 5JEAG 4DR7H 1X9ZA 4DV5H 4DV7H 2AXYA 4JI8H 2HH2A 3J7AK 1KHMA 5FLXW 2JA9A 1J4WA 4GKKH 4FJSA 3KDGA 2DGRA 4DUYH 1WE8A 4LFBH 4JVHA 2CTEA 1EC6A 2HH3A 4LF7H 1ZZKA 1IBMH 1X4NA 1WHRA 2JEBI 3KDKA 4LF6H 4DV4H 5C0XG 2JEAI 1N36H 2PT7G 2LRRA 4B3MH 4OD6A 4AIMA 2UXDH 3OETA 2FMRA 2UXCH 4JYAH 4FJUA 2NN6G 3EZJA 1K1GA 3FAUA 3AEVB 3UOEA 3GR5A 1N33H 4NBQA 2OPUA 3I0PA 2CTFA 4AQYH 2CTJA 2CPQA 2G8YA 4JI4H 2HHHH 5K36G 1HNZH 3GKUA 4PDBA 2QNDA 2X06A 2UU9H 4X66H 2CTKA 2K1HA 2M8WA 2P2RA 1N32H 1SEIA 4LF4H 2Y3MA 1MSZA 2BL5A 2UUBH 5DT9A 4WANA 4E9JA 4X65H 2ANRA 3OTOH 1X0AA 4B3SH 1VIGA 3RF2A 1DT4A
chains in the Genus database with same CATH topology
4AIMA 1DTJA 2FMRA 3V69A 4B8TA 2CTMA 4JVYA 4BA2I 2NN6G 1K1GA 2CTLA 3AEVB 4NBQA 1TUAA 1WVNA 2OPUA 4LIJA 1VIHA 2CTFA 2CTJA 2CPQA 4WALA 1ZTGA 2MJHA 2JVZA 2PQUA 4OO1G 5K36G 2BA0A 2QNDA 4AM3A 3U1KA 5JEAG 2ANNA 4BA1I 1X4MA 2JE6I 2AXYA 2HH2A 1ZZJA 2CTKA 2PY9A 1KHMA 2P2RA 2JA9A 1J4WA 2DGRA 1WE8A 2BL5A 3L7ZC 4JVHA 2CTEA 1EC6A 2HH3A 2OPVA 4QMFB 1ZZKA 4IFDG 4WANA 2YQRA 1ZZIA 1J5KA 2ANRA 3VKEA 1X4NA 2E3UA 2JEBI 2JZXA 1VIGA 5C0XG 2JEAI 2Z0SA 1DT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AIM A;  1DTJ A;  2FMR A;  3V69 A;  4B8T A;  2CTM A;  4JVY A;  4BA2 I;  2NN6 G;  1K1G A;  2CTL A;  3AEV B;  4NBQ A;  1TUA A;  1WVN A;  2OPU A;  4LIJ A;  1VIH A;  2CTF A;  2CTJ A;  2CPQ A;  4WAL A;  1ZTG A;  2MJH A;  2JVZ A;  2PQU A;  4OO1 G;  5K36 G;  2BA0 A;  2QND A;  4AM3 A;  3U1K A;  5JEA G;  2ANN A;  4BA1 I;  1X4M A;  2JE6 I;  2AXY A;  2HH2 A;  1ZZJ A;  2CTK A;  2PY9 A;  1KHM A;  2P2R A;  2JA9 A;  1J4W A;  2DGR A;  1WE8 A;  2BL5 A;  3L7Z C;  4JVH A;  2CTE A;  1EC6 A;  2HH3 A;  2OPV A;  4QMF B;  1ZZK A;  4IFD G;  4WAN A;  2YQR A;  1ZZI A;  1J5K A;  2ANR A;  3VKE A;  1X4N A;  2E3U A;  2JEB I;  2JZX A;  1VIG A;  5C0X G;  2JEA I;  2Z0S A;  1DT4 A; 
#chains in the Genus database with same CATH topology
 4B8C D;  2FPH X;  3SB1 A;  3T1Y H;  4LFC H;  2CTM A;  4OX9 H;  4YHH H;  1FKA H;  2CTL A;  2D9I A;  4NZT M;  4JI1 H;  1WVN A;  4EC5 A;  2A1S A;  4B3R H;  2MJH A;  4DV0 H;  1ZTG A;  4B3T H;  2JVZ A;  3T1H H;  5LL6 b;  1S20 A;  5IT9 W;  2M6Q A;  4JI3 H;  4BA1 I;  1X4M A;  4LF8 H;  2PY9 A;  1ZZJ A;  5BR8 H;  1HR0 H;  4NXM H;  4K0K H;  3JAM W;  4NZR M;  1NXU A;  2ZM6 H;  3L7Z C;  1XMO H;  4QMF B;  5A2Q W;  2ZQE A;  4LFA H;  4DV1 H;  4LF9 H;  4JV5 H;  3VKE A;  2E3U A;  4DR3 H;  4GKJ H;  4JVY A;  4JI2 H;  2Z0S A;  2F4V H;  1XMQ H;  1DTJ A;  1XNR H;  1IBL H;  4JI6 H;  4G08 A;  3V69 A;  4B8T A;  1J5E H;  1PQX A;  4JI5 H;  2CWF A;  1I6U A;  1TUA A;  2UUC H;  2CWH A;  1V8C A;  4X62 H;  2VQF H;  1XRH A;  5IWA H;  4WAL A;  4DR2 H;  3J80 W;  3OSS D;  2PQU A;  4YY3 H;  4AM3 A;  2ANN A;  2CPM A;  2JE6 I;  2LTL A;  1ODH A;  4NXN H;  2LF0 A;  1VBI A;  1AN7 A;  4DV2 H;  4DR1 H;  1WTJ A;  3GAB A;  3J81 W;  2OPV A;  1S03 G;  4IFD G;  2UXB H;  3QD7 X;  2YQR A;  1ZZI A;  1J5K A;  4JI7 H;  1V9N A;  4OCH A;  2O4C A;  5LMN H;  1Z2I A;  2E5L H;  4JI0 H;  2JZX A;  2VKC A;  4DUZ H;  4DV3 H;  5LMU H;  1I94 H;  4BA2 I;  2FFM A;  4DR4 H;  1F0X A;  1N34 H;  4LF5 H;  1FJG H;  4LIJ A;  2VQE H;  1VIH A;  4DR5 H;  2UUA H;  1UG8 A;  4KHP H;  1XNQ H;  1HNW H;  4DR6 H;  4DV6 H;  4H8A A;  1IBK H;  2BA0 A;  4OO1 G;  4X64 H;  2LTM A;  3U1K A;  3NCV A;  1HNX H;  5JEA G;  4DR7 H;  1X9Z A;  4DV5 H;  4DV7 H;  2AXY A;  4JI8 H;  2HH2 A;  3J7A K;  1KHM A;  5FLX W;  2JA9 A;  1J4W A;  4GKK H;  4FJS A;  3KDG A;  2DGR A;  4DUY H;  1WE8 A;  4LFB H;  4JVH A;  2CTE A;  1EC6 A;  2HH3 A;  4LF7 H;  1ZZK A;  1IBM H;  1X4N A;  1WHR A;  2JEB I;  3KDK A;  4LF6 H;  4DV4 H;  5C0X G;  2JEA I;  1N36 H;  2PT7 G;  2LRR A;  4B3M H;  4OD6 A;  4AIM A;  2UXD H;  3OET A;  2FMR A;  2UXC H;  4JYA H;  4FJU A;  2NN6 G;  3EZJ A;  1K1G A;  3FAU A;  3AEV B;  3UOE A;  3GR5 A;  1N33 H;  4NBQ A;  2OPU A;  3I0P A;  2CTF A;  4AQY H;  2CTJ A;  2CPQ A;  2G8Y A;  4JI4 H;  2HHH H;  5K36 G;  1HNZ H;  3GKU A;  4PDB A;  2QND A;  2X06 A;  2UU9 H;  4X66 H;  2CTK A;  2K1H A;  2M8W A;  2P2R A;  1N32 H;  1SEI A;  4LF4 H;  2Y3M A;  1MSZ A;  2BL5 A;  2UUB H;  5DT9 A;  4WAN A;  4E9J A;  4X65 H;  2ANR A;  3OTO H;  1X0A A;  4B3S H;  1VIG A;  3RF2 A;  1DT4 A; 
#chains in the Genus database with same CATH homology
 4AIM A;  1DTJ A;  2FMR A;  3V69 A;  4B8T A;  2CTM A;  4JVY A;  4BA2 I;  2NN6 G;  1K1G A;  2CTL A;  3AEV B;  4NBQ A;  1TUA A;  1WVN A;  2OPU A;  4LIJ A;  1VIH A;  2CTF A;  2CTJ A;  2CPQ A;  4WAL A;  1ZTG A;  2MJH A;  2JVZ A;  2PQU A;  4OO1 G;  5K36 G;  2BA0 A;  2QND A;  4AM3 A;  3U1K A;  5JEA G;  2ANN A;  4BA1 I;  1X4M A;  2JE6 I;  2AXY A;  2HH2 A;  1ZZJ A;  2CTK A;  2PY9 A;  1KHM A;  2P2R A;  2JA9 A;  1J4W A;  2DGR A;  1WE8 A;  2BL5 A;  3L7Z C;  4JVH A;  2CTE A;  1EC6 A;  2HH3 A;  2OPV A;  4QMF B;  1ZZK A;  4IFD G;  4WAN A;  2YQR A;  1ZZI A;  1J5K A;  2ANR A;  3VKE A;  1X4N A;  2E3U A;  2JEB I;  2JZX A;  1VIG A;  5C0X G;  2JEA I;  2Z0S A;  1DT4 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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