2HH3A

Solution structure of the third kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
71
structure length
71
Chain Sequence
GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh3A00
2FMRA 1VIGA 2PY9A 2CTJA 4OO1G 4AM3A 2ANRA 1WVNA 3U1KA 4LIJA 3AEVB 2P2RA 1TUAA 2CTKA 1X4MA 1WE8A 2OPVA 4WALA 4IFDG 2CPQA 4JVHA 5K36G 1X4NA 2Z0SA 2JEAI 2CTEA 1ZTGA 4WANA 2BA0A 3VKEA 4NBQA 1ZZIA 4BA2I 1KHMA 4AIMA 1ZZJA 2ANNA 4JVYA 2CTMA 2CTLA 2DGRA 4QMFB 4BA1I 4B8TA 2NN6G 2JE6I 1EC6A 1K1GA 2JEBI 2JA9A 1DT4A 2CTFA 3L7ZC 3V69A 1J4WA 2YQRA 2PQUA 2HH2A 5C0XG 1ZZKA 1VIHA 2E3UA 2HH3A 2JVZA 2OPUA 2JZXA 2AXYA 2MJHA 2BL5A 1J5KA 5JEAG 1DTJA 2QNDA
chains in the Genus database with same CATH superfamily
4PDBA 4B8CD 4LF7H 4OO1G 1WTJA 2O4CA 2FPHX 1X0AA 3U1KA 5A2QW 1V9NA 4LIJA 4DV2H 2ANRA 2P2RA 2UUAH 3AEVB 1WE8A 3KDGA 1ODHA 2CPQA 4DR6H 1X4NA 1ZZIA 3SB1A 5IWAH 4BA2I 1KHMA 1ZZJA 2CTMA 2FFMA 4JI1H 4LFAH 4NXNH 2X06A 4DR4H 2Y3MA 1EC6A 4X66H 2D9IA 4B3MH 2G8YA 5DT9A 1IBKH 3OSSD 2YQRA 4B3RH 5C0XG 4OCHA 4K0KH 1ZZKA 4OD6A 3T1HH 2OPUA 4DV7H 4LF8H 4H8AA 4E9JA 4LFBH 2FMRA 1VIGA 1NXUA 4YY3H 2PY9A 2UXDH 5LL6b 1X9ZA 4X62H 1WVNA 4DUYH 1AN7A 3I0PA 2CTKA 4X64H 1N34H 4IFDG 4JVHA 5K36G 4YHHH 1VBIA 3GABA 2CWHA 2Z0SA 2A1SA 1XMOH 2VQFH 2VKCA 3VKEA 4NBQA 4AQYH 1N36H 4WANA 5IT9W 2ZM6H 4QMFB 1SEIA 4B8TA 4LF4H 1HNXH 2UU9H 4DR2H 4NZRM 4DV5H 2JA9A 2CTFA 3L7ZC 2HHHH 4JI8H 4DV3H 3KDKA 1J5EH 2HH2A 2M8WA 2E3UA 1VIHA 1S20A 2HH3A 2K1HA 3OETA 3J81W 2JZXA 5LMNH 2UXCH 1J5KA 4JYAH 3FAUA 4FJUA 1DTJA 5JEAG 4DV1H 4LF9H 1V8CA 1XNRH 1TUAA 2OPVA 1X4MA 4X65H 4WALA 1I94H 4B3TH 2LTMA 4JI7H 2JEAI 5BR8H 4NZTM 2ZQEA 1IBMH 4JI2H 4JI3H 4AIMA 1HNWH 3NCVA 4JVYA 2CTLA 2UUCH 4BA1I 2M6QA 3T1YH 2NN6G 4LF6H 2JE6I 1S03G 1K1GA 2JEBI 1DT4A 3V69A 1F0XA 4LF5H 2CPMA 1J4WA 4JI5H 4OX9H 2F4VH 1FKAH 4B3SH 4LFCH 3JAMW 2MJHA 1Z2IA 2BL5A 1UG8A 2LRRA 1XMQH 2UUBH 1HNZH 3J80W 5LMUH 4JI0H 2CTJA 1FJGH 4AM3A 2LTLA 3UOEA 3EZJA 1WHRA 4DV4H 3J7AK 1N33H 2CWFA 4JI4H 4EC5A 3GR5A 2UXBH 1I6UA 3OTOH 3QD7X 5FLXW 2CTEA 1ZTGA 4FJSA 2BA0A 4JV5H 4G08A 4DR7H 2E5LH 2ANNA 2DGRA 4DV0H 4NXMH 2VQEH 2LF0A 1HR0H 4KHPH 4DR3H 4JI6H 4GKJH 1XRHA 1MSZA 4GKKH 4DR1H 2PT7G 1N32H 4DR5H 1XNQH 1PQXA 2JVZA 4DV6H 2AXYA 1IBLH 2PQUA 3GKUA 2QNDA 4DUZH 3RF2A
chains in the Genus database with same CATH topology
2FMRA 1VIGA 2PY9A 2CTJA 4OO1G 4AM3A 2ANRA 1WVNA 3U1KA 4LIJA 3AEVB 2P2RA 1TUAA 2CTKA 1X4MA 1WE8A 2OPVA 4WALA 4IFDG 2CPQA 4JVHA 5K36G 1X4NA 2Z0SA 2JEAI 2CTEA 1ZTGA 4WANA 2BA0A 3VKEA 4NBQA 1ZZIA 4BA2I 1KHMA 4AIMA 1ZZJA 2ANNA 4JVYA 2CTMA 2CTLA 2DGRA 4QMFB 4BA1I 4B8TA 2NN6G 2JE6I 1EC6A 1K1GA 2JEBI 2JA9A 1DT4A 2CTFA 3L7ZC 3V69A 1J4WA 2YQRA 2PQUA 2HH2A 5C0XG 1ZZKA 1VIHA 2E3UA 2HH3A 2JVZA 2OPUA 2JZXA 2AXYA 2MJHA 2BL5A 1J5KA 5JEAG 1DTJA 2QNDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FMR A;  1VIG A;  2PY9 A;  2CTJ A;  4OO1 G;  4AM3 A;  2ANR A;  1WVN A;  3U1K A;  4LIJ A;  3AEV B;  2P2R A;  1TUA A;  2CTK A;  1X4M A;  1WE8 A;  2OPV A;  4WAL A;  4IFD G;  2CPQ A;  4JVH A;  5K36 G;  1X4N A;  2Z0S A;  2JEA I;  2CTE A;  1ZTG A;  4WAN A;  2BA0 A;  3VKE A;  4NBQ A;  1ZZI A;  4BA2 I;  1KHM A;  4AIM A;  1ZZJ A;  2ANN A;  4JVY A;  2CTM A;  2CTL A;  2DGR A;  4QMF B;  4BA1 I;  4B8T A;  2NN6 G;  2JE6 I;  1EC6 A;  1K1G A;  2JEB I;  2JA9 A;  1DT4 A;  2CTF A;  3L7Z C;  3V69 A;  1J4W A;  2YQR A;  2PQU A;  2HH2 A;  5C0X G;  1ZZK A;  1VIH A;  2E3U A;  2HH3 A;  2JVZ A;  2OPU A;  2JZX A;  2AXY A;  2MJH A;  2BL5 A;  1J5K A;  5JEA G;  1DTJ A;  2QND A; 
#chains in the Genus database with same CATH topology
 4PDB A;  4B8C D;  4LF7 H;  4OO1 G;  1WTJ A;  2O4C A;  2FPH X;  1X0A A;  3U1K A;  5A2Q W;  1V9N A;  4LIJ A;  4DV2 H;  2ANR A;  2P2R A;  2UUA H;  3AEV B;  1WE8 A;  3KDG A;  1ODH A;  2CPQ A;  4DR6 H;  1X4N A;  1ZZI A;  3SB1 A;  5IWA H;  4BA2 I;  1KHM A;  1ZZJ A;  2CTM A;  2FFM A;  4JI1 H;  4LFA H;  4NXN H;  2X06 A;  4DR4 H;  2Y3M A;  1EC6 A;  4X66 H;  2D9I A;  4B3M H;  2G8Y A;  5DT9 A;  1IBK H;  3OSS D;  2YQR A;  4B3R H;  5C0X G;  4OCH A;  4K0K H;  1ZZK A;  4OD6 A;  3T1H H;  2OPU A;  4DV7 H;  4LF8 H;  4H8A A;  4E9J A;  4LFB H;  2FMR A;  1VIG A;  1NXU A;  4YY3 H;  2PY9 A;  2UXD H;  5LL6 b;  1X9Z A;  4X62 H;  1WVN A;  4DUY H;  1AN7 A;  3I0P A;  2CTK A;  4X64 H;  1N34 H;  4IFD G;  4JVH A;  5K36 G;  4YHH H;  1VBI A;  3GAB A;  2CWH A;  2Z0S A;  2A1S A;  1XMO H;  2VQF H;  2VKC A;  3VKE A;  4NBQ A;  4AQY H;  1N36 H;  4WAN A;  5IT9 W;  2ZM6 H;  4QMF B;  1SEI A;  4B8T A;  4LF4 H;  1HNX H;  2UU9 H;  4DR2 H;  4NZR M;  4DV5 H;  2JA9 A;  2CTF A;  3L7Z C;  2HHH H;  4JI8 H;  4DV3 H;  3KDK A;  1J5E H;  2HH2 A;  2M8W A;  2E3U A;  1VIH A;  1S20 A;  2HH3 A;  2K1H A;  3OET A;  3J81 W;  2JZX A;  5LMN H;  2UXC H;  1J5K A;  4JYA H;  3FAU A;  4FJU A;  1DTJ A;  5JEA G;  4DV1 H;  4LF9 H;  1V8C A;  1XNR H;  1TUA A;  2OPV A;  1X4M A;  4X65 H;  4WAL A;  1I94 H;  4B3T H;  2LTM A;  4JI7 H;  2JEA I;  5BR8 H;  4NZT M;  2ZQE A;  1IBM H;  4JI2 H;  4JI3 H;  4AIM A;  1HNW H;  3NCV A;  4JVY A;  2CTL A;  2UUC H;  4BA1 I;  2M6Q A;  3T1Y H;  2NN6 G;  4LF6 H;  2JE6 I;  1S03 G;  1K1G A;  2JEB I;  1DT4 A;  3V69 A;  1F0X A;  4LF5 H;  2CPM A;  1J4W A;  4JI5 H;  4OX9 H;  2F4V H;  1FKA H;  4B3S H;  4LFC H;  3JAM W;  2MJH A;  1Z2I A;  2BL5 A;  1UG8 A;  2LRR A;  1XMQ H;  2UUB H;  1HNZ H;  3J80 W;  5LMU H;  4JI0 H;  2CTJ A;  1FJG H;  4AM3 A;  2LTL A;  3UOE A;  3EZJ A;  1WHR A;  4DV4 H;  3J7A K;  1N33 H;  2CWF A;  4JI4 H;  4EC5 A;  3GR5 A;  2UXB H;  1I6U A;  3OTO H;  3QD7 X;  5FLX W;  2CTE A;  1ZTG A;  4FJS A;  2BA0 A;  4JV5 H;  4G08 A;  4DR7 H;  2E5L H;  2ANN A;  2DGR A;  4DV0 H;  4NXM H;  2VQE H;  2LF0 A;  1HR0 H;  4KHP H;  4DR3 H;  4JI6 H;  4GKJ H;  1XRH A;  1MSZ A;  4GKK H;  4DR1 H;  2PT7 G;  1N32 H;  4DR5 H;  1XNQ H;  1PQX A;  2JVZ A;  4DV6 H;  2AXY A;  1IBL H;  2PQU A;  3GKU A;  2QND A;  4DUZ H;  3RF2 A; 
#chains in the Genus database with same CATH homology
 2FMR A;  1VIG A;  2PY9 A;  2CTJ A;  4OO1 G;  4AM3 A;  2ANR A;  1WVN A;  3U1K A;  4LIJ A;  3AEV B;  2P2R A;  1TUA A;  2CTK A;  1X4M A;  1WE8 A;  2OPV A;  4WAL A;  4IFD G;  2CPQ A;  4JVH A;  5K36 G;  1X4N A;  2Z0S A;  2JEA I;  2CTE A;  1ZTG A;  4WAN A;  2BA0 A;  3VKE A;  4NBQ A;  1ZZI A;  4BA2 I;  1KHM A;  4AIM A;  1ZZJ A;  2ANN A;  4JVY A;  2CTM A;  2CTL A;  2DGR A;  4QMF B;  4BA1 I;  4B8T A;  2NN6 G;  2JE6 I;  1EC6 A;  1K1G A;  2JEB I;  2JA9 A;  1DT4 A;  2CTF A;  3L7Z C;  3V69 A;  1J4W A;  2YQR A;  2PQU A;  2HH2 A;  5C0X G;  1ZZK A;  1VIH A;  2E3U A;  2HH3 A;  2JVZ A;  2OPU A;  2JZX A;  2AXY A;  2MJH A;  2BL5 A;  1J5K A;  5JEA G;  1DTJ A;  2QND A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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