2LRRA

Solution structure of the r3h domain from human smubp-2 in complex with 2'-deoxyguanosine-5'-monophosphate
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
70
structure length
70
Chain Sequence
PEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for 5'-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Smubp-2
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DNA-binding protein SMUBP-2
total genus 20
structure length 70
sequence length 70
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2012-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01424 R3H R3H domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.50 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 R3H-like domain 2lrrA00
2CPMA 1MSZA 2A1SA 1WHRA 1UG8A 2LRRA 3GKUA
chains in the Genus database with same CATH superfamily
4DR4H 2VQFH 1IBKH 3J81W 1J5KA 4DR1H 1DTJA 1VBIA 3RF2A 4WALA 1XMOH 1EC6A 4IFDG 2JZXA 2CTEA 4DV6H 2M8WA 1DT4A 1XRHA 1ZZIA 1XMQH 2UUAH 4LF7H 2VKCA 3GABA 3VKEA 3I0PA 2X06A 4DV0H 4JI3H 1UG8A 2Y3MA 3KDGA 4LFAH 3T1HH 1J5EH 4EC5A 4LFBH 3FAUA 4DV4H 4AQYH 4B8CD 3J80W 5LMUH 4LF5H 2F4VH 2UXBH 2CTFA 4BA2I 4JI5H 3NCVA 4LF6H 4NXMH 1XNQH 1VIHA 3GKUA 4JVYA 4LF4H 2CPMA 1J4WA 3OSSD 4E9JA 4JVHA 4WANA 1NXUA 2DGRA 5C0XG 1I94H 1XNRH 4DR7H 5BR8H 2CTMA 2LF0A 4B8TA 4DR3H 1WVNA 2MJHA 2A1SA 2UXCH 1N32H 2PQUA 1ZZKA 3L7ZC 2Z0SA 4G08A 4JI7H 1IBLH 1IBMH 5K36G 4FJSA 2YQRA 1ODHA 2QNDA 4DV5H 2UUCH 3J7AK 2LRRA 1HNWH 2CPQA 4FJUA 2P2RA 5FLXW 4LF8H 2CTKA 3AEVB 4K0KH 4DV7H 4OCHA 3V69A 2LTMA 2OPVA 2JVZA 4JYAH 4X64H 1FJGH 4OX9H 4DV1H 5A2QW 4AM3A 3UOEA 1VIGA 2CTLA 3SB1A 2UU9H 4JV5H 1WTJA 2FPHX 2NN6G 4DR6H 4X66H 2CWFA 1ZZJA 2E5LH 4B3TH 1WE8A 4NXNH 2JA9A 4X65H 4LF9H 2CWHA 4B3MH 3OTOH 1HR0H 5IWAH 4BA1I 4GKKH 2JEAI 1ZTGA 3QD7X 4DV3H 4JI1H 4H8AA 1F0XA 2FFMA 2PT7G 4AIMA 1K1GA 4JI8H 2ANRA 3KDKA 4DV2H 5DT9A 4OD6A 2O4CA 4JI4H 1WHRA 2HH3A 2BL5A 2ZQEA 5JEAG 1FKAH 1I6UA 3EZJA 3U1KA 4NZRM 1N33H 4PDBA 2PY9A 1X4NA 2HHHH 2UXDH 2ZM6H 4X62H 1V8CA 2AXYA 1PQXA 5IT9W 3T1YH 2ANNA 1SEIA 4LIJA 1X4MA 3GR5A 1S20A 2JEBI 1MSZA 4DUZH 4LFCH 2FMRA 2JE6I 1Z2IA 1N36H 4YY3H 2D9IA 3JAMW 5LL6b 4DR2H 4NZTM 1S03G 1KHMA 2VQEH 2BA0A 4KHPH 1X9ZA 1V9NA 2LTLA 2K1HA 4QMFB 2M6QA 5LMNH 1HNXH 1AN7A 1TUAA 2OPUA 4OO1G 4GKJH 2G8YA 4B3SH 4JI6H 4B3RH 1HNZH 2UUBH 4DUYH 1N34H 3OETA 4JI2H 4YHHH 2CTJA 2E3UA 4NBQA 4JI0H 1X0AA 4DR5H 2HH2A
chains in the Genus database with same CATH topology
2CPMA 1MSZA 2A1SA 1WHRA 1UG8A 2LRRA 3GKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CPM A;  1MSZ A;  2A1S A;  1WHR A;  1UG8 A;  2LRR A;  3GKU A; 
#chains in the Genus database with same CATH topology
 4DR4 H;  2VQF H;  1IBK H;  3J81 W;  1J5K A;  4DR1 H;  1DTJ A;  1VBI A;  3RF2 A;  4WAL A;  1XMO H;  1EC6 A;  4IFD G;  2JZX A;  2CTE A;  4DV6 H;  2M8W A;  1DT4 A;  1XRH A;  1ZZI A;  1XMQ H;  2UUA H;  4LF7 H;  2VKC A;  3GAB A;  3VKE A;  3I0P A;  2X06 A;  4DV0 H;  4JI3 H;  1UG8 A;  2Y3M A;  3KDG A;  4LFA H;  3T1H H;  1J5E H;  4EC5 A;  4LFB H;  3FAU A;  4DV4 H;  4AQY H;  4B8C D;  3J80 W;  5LMU H;  4LF5 H;  2F4V H;  2UXB H;  2CTF A;  4BA2 I;  4JI5 H;  3NCV A;  4LF6 H;  4NXM H;  1XNQ H;  1VIH A;  3GKU A;  4JVY A;  4LF4 H;  2CPM A;  1J4W A;  3OSS D;  4E9J A;  4JVH A;  4WAN A;  1NXU A;  2DGR A;  5C0X G;  1I94 H;  1XNR H;  4DR7 H;  5BR8 H;  2CTM A;  2LF0 A;  4B8T A;  4DR3 H;  1WVN A;  2MJH A;  2A1S A;  2UXC H;  1N32 H;  2PQU A;  1ZZK A;  3L7Z C;  2Z0S A;  4G08 A;  4JI7 H;  1IBL H;  1IBM H;  5K36 G;  4FJS A;  2YQR A;  1ODH A;  2QND A;  4DV5 H;  2UUC H;  3J7A K;  2LRR A;  1HNW H;  2CPQ A;  4FJU A;  2P2R A;  5FLX W;  4LF8 H;  2CTK A;  3AEV B;  4K0K H;  4DV7 H;  4OCH A;  3V69 A;  2LTM A;  2OPV A;  2JVZ A;  4JYA H;  4X64 H;  1FJG H;  4OX9 H;  4DV1 H;  5A2Q W;  4AM3 A;  3UOE A;  1VIG A;  2CTL A;  3SB1 A;  2UU9 H;  4JV5 H;  1WTJ A;  2FPH X;  2NN6 G;  4DR6 H;  4X66 H;  2CWF A;  1ZZJ A;  2E5L H;  4B3T H;  1WE8 A;  4NXN H;  2JA9 A;  4X65 H;  4LF9 H;  2CWH A;  4B3M H;  3OTO H;  1HR0 H;  5IWA H;  4BA1 I;  4GKK H;  2JEA I;  1ZTG A;  3QD7 X;  4DV3 H;  4JI1 H;  4H8A A;  1F0X A;  2FFM A;  2PT7 G;  4AIM A;  1K1G A;  4JI8 H;  2ANR A;  3KDK A;  4DV2 H;  5DT9 A;  4OD6 A;  2O4C A;  4JI4 H;  1WHR A;  2HH3 A;  2BL5 A;  2ZQE A;  5JEA G;  1FKA H;  1I6U A;  3EZJ A;  3U1K A;  4NZR M;  1N33 H;  4PDB A;  2PY9 A;  1X4N A;  2HHH H;  2UXD H;  2ZM6 H;  4X62 H;  1V8C A;  2AXY A;  1PQX A;  5IT9 W;  3T1Y H;  2ANN A;  1SEI A;  4LIJ A;  1X4M A;  3GR5 A;  1S20 A;  2JEB I;  1MSZ A;  4DUZ H;  4LFC H;  2FMR A;  2JE6 I;  1Z2I A;  1N36 H;  4YY3 H;  2D9I A;  3JAM W;  5LL6 b;  4DR2 H;  4NZT M;  1S03 G;  1KHM A;  2VQE H;  2BA0 A;  4KHP H;  1X9Z A;  1V9N A;  2LTL A;  2K1H A;  4QMF B;  2M6Q A;  5LMN H;  1HNX H;  1AN7 A;  1TUA A;  2OPU A;  4OO1 G;  4GKJ H;  2G8Y A;  4B3S H;  4JI6 H;  4B3R H;  1HNZ H;  2UUB H;  4DUY H;  1N34 H;  3OET A;  4JI2 H;  4YHH H;  2CTJ A;  2E3U A;  4NBQ A;  4JI0 H;  1X0A A;  4DR5 H;  2HH2 A; 
#chains in the Genus database with same CATH homology
 2CPM A;  1MSZ A;  2A1S A;  1WHR A;  1UG8 A;  2LRR A;  3GKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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