2OPUA

Solution nmr structure of the first domain of ksrp
Total Genus 24
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
89
structure length
89
Chain Sequence
ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KHSRP protein
total genus 24
structure length 89
sequence length 89
ec nomenclature
pdb deposition date 2007-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2opuA00
2BA0A 2CTKA 2CTMA 4QMFB 2CTLA 4BA2I 2ANRA 2NN6G 2JVZA 2AXYA 2PY9A 2Z0SA 2CTEA 1VIGA 2YQRA 3V69A 4OO1G 1WE8A 1ZTGA 4IFDG 1EC6A 2FMRA 2E3UA 2JE6I 1VIHA 1WVNA 1TUAA 2OPVA 3L7ZC 5JEAG 4B8TA 4AM3A 5K36G 5C0XG 2JEBI 2QNDA 4JVYA 4WANA 1X4MA 2JEAI 4JVHA 2HH3A 2OPUA 2MJHA 1ZZKA 2CTJA 2CTFA 2DGRA 4NBQA 4AIMA 4WALA 4BA1I 1DT4A 1DTJA 1J5KA 1ZZIA 3U1KA 1X4NA 3VKEA 1J4WA 1K1GA 2CPQA 2HH2A 2JA9A 4LIJA 1ZZJA 2PQUA 2ANNA 3AEVB 2BL5A 2JZXA 1KHMA 2P2RA
chains in the Genus database with same CATH superfamily
2BA0A 2CTMA 3J81W 2E5LH 2PY9A 2Z0SA 3V69A 4LFCH 1IBKH 1HR0H 4JI0H 4LFBH 4X64H 2OPVA 2VKCA 3L7ZC 4YY3H 4B8TA 1N32H 3GKUA 4G08A 5C0XG 1WHRA 3KDGA 5LL6b 4DV2H 4EC5A 1J5EH 2JEAI 4DV0H 2HH3A 3EZJA 2FPHX 2CPMA 2OPUA 4DV6H 2CTJA 2A1SA 4NBQA 2UU9H 4LF6H 4BA1I 4DV4H 3NCVA 3GR5A 3U1KA 3VKEA 1FKAH 4NXMH 1AN7A 4DV5H 2JA9A 2ANNA 2PQUA 4LF8H 4JI8H 4GKKH 4B3TH 2BL5A 1MSZA 2UXCH 4OX9H 2VQEH 2P2RA 2CTKA 2X06A 4QMFB 4LFAH 4X62H 4FJSA 1N36H 1X9ZA 1HNXH 4OD6A 4LF4H 4B3SH 1UG8A 4K0KH 4YHHH 2YQRA 1VIGA 1V9NA 2LRRA 2ZM6H 1XNRH 4IFDG 4JV5H 4OO1G 2HHHH 5LMNH 4DV3H 1HNZH 2UUCH 4DUYH 1NXUA 2JEBI 2QNDA 3I0PA 4JI7H 2LTMA 4H8AA 4WANA 4JI5H 3KDKA 4JYAH 3T1HH 4JI6H 3JAMW 1ZZKA 2ZQEA 4FJUA 4AIMA 1DT4A 1DTJA 3UOEA 1ZZIA 1VBIA 4E9JA 3OTOH 1S03G 1J4WA 4LIJA 4NXNH 1IBLH 1N33H 4DR6H 5IT9W 2CTLA 2LTLA 3FAUA 4X65H 5LMUH 4BA2I 4JI2H 4DV1H 3OSSD 2PT7G 4LF7H 4NZTM 2FMRA 1X0AA 5A2QW 1VIHA 4B8CD 1TUAA 5JEAG 4AM3A 4DR4H 5K36G 3J7AK 2LF0A 4JVHA 1S20A 1F0XA 2MJHA 1XNQH 2CTFA 4WALA 4LF9H 1V8CA 3T1YH 1J5KA 4DR7H 1IBMH 2UXBH 5IWAH 2CWFA 1SEIA 2CWHA 4NZRM 1X4NA 4DR2H 5BR8H 1PQXA 3OETA 1XMOH 2HH2A 1K1GA 3AEVB 2UXDH 4DV7H 4DUZH 1XRHA 4DR3H 2Y3MA 4AQYH 1I94H 2F4VH 2G8YA 1WTJA 5FLXW 3RF2A 2D9IA 2FFMA 2M6QA 2ANRA 3J80W 4JI3H 2NN6G 2JVZA 3GABA 2AXYA 1XMQH 1Z2IA 2CTEA 2UUBH 1FJGH 1EC6A 1WE8A 1N34H 1ZTGA 4LF5H 2E3UA 2JE6I 2UUAH 1WVNA 2M8WA 2O4CA 3SB1A 4JI1H 4KHPH 1HNWH 4JVYA 1X4MA 4X66H 4DR1H 3QD7X 2DGRA 4B3MH 2K1HA 4JI4H 5DT9A 2VQFH 4GKJH 2CPQA 1ZZJA 4PDBA 4OCHA 4DR5H 1I6UA 1ODHA 2JZXA 4B3RH 1KHMA
chains in the Genus database with same CATH topology
2BA0A 2CTKA 2CTMA 4QMFB 2CTLA 4BA2I 2ANRA 2NN6G 2JVZA 2AXYA 2PY9A 2Z0SA 2CTEA 1VIGA 2YQRA 3V69A 4OO1G 1WE8A 1ZTGA 4IFDG 1EC6A 2FMRA 2E3UA 2JE6I 1VIHA 1WVNA 1TUAA 2OPVA 3L7ZC 5JEAG 4B8TA 4AM3A 5K36G 5C0XG 2JEBI 2QNDA 4JVYA 4WANA 1X4MA 2JEAI 4JVHA 2HH3A 2OPUA 2MJHA 1ZZKA 2CTJA 2CTFA 2DGRA 4NBQA 4AIMA 4WALA 4BA1I 1DT4A 1DTJA 1J5KA 1ZZIA 3U1KA 1X4NA 3VKEA 1J4WA 1K1GA 2CPQA 2HH2A 2JA9A 4LIJA 1ZZJA 2PQUA 2ANNA 3AEVB 2BL5A 2JZXA 1KHMA 2P2RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BA0 A;  2CTK A;  2CTM A;  4QMF B;  2CTL A;  4BA2 I;  2ANR A;  2NN6 G;  2JVZ A;  2AXY A;  2PY9 A;  2Z0S A;  2CTE A;  1VIG A;  2YQR A;  3V69 A;  4OO1 G;  1WE8 A;  1ZTG A;  4IFD G;  1EC6 A;  2FMR A;  2E3U A;  2JE6 I;  1VIH A;  1WVN A;  1TUA A;  2OPV A;  3L7Z C;  5JEA G;  4B8T A;  4AM3 A;  5K36 G;  5C0X G;  2JEB I;  2QND A;  4JVY A;  4WAN A;  1X4M A;  2JEA I;  4JVH A;  2HH3 A;  2OPU A;  2MJH A;  1ZZK A;  2CTJ A;  2CTF A;  2DGR A;  4NBQ A;  4AIM A;  4WAL A;  4BA1 I;  1DT4 A;  1DTJ A;  1J5K A;  1ZZI A;  3U1K A;  1X4N A;  3VKE A;  1J4W A;  1K1G A;  2CPQ A;  2HH2 A;  2JA9 A;  4LIJ A;  1ZZJ A;  2PQU A;  2ANN A;  3AEV B;  2BL5 A;  2JZX A;  1KHM A;  2P2R A; 
#chains in the Genus database with same CATH topology
 2BA0 A;  2CTM A;  3J81 W;  2E5L H;  2PY9 A;  2Z0S A;  3V69 A;  4LFC H;  1IBK H;  1HR0 H;  4JI0 H;  4LFB H;  4X64 H;  2OPV A;  2VKC A;  3L7Z C;  4YY3 H;  4B8T A;  1N32 H;  3GKU A;  4G08 A;  5C0X G;  1WHR A;  3KDG A;  5LL6 b;  4DV2 H;  4EC5 A;  1J5E H;  2JEA I;  4DV0 H;  2HH3 A;  3EZJ A;  2FPH X;  2CPM A;  2OPU A;  4DV6 H;  2CTJ A;  2A1S A;  4NBQ A;  2UU9 H;  4LF6 H;  4BA1 I;  4DV4 H;  3NCV A;  3GR5 A;  3U1K A;  3VKE A;  1FKA H;  4NXM H;  1AN7 A;  4DV5 H;  2JA9 A;  2ANN A;  2PQU A;  4LF8 H;  4JI8 H;  4GKK H;  4B3T H;  2BL5 A;  1MSZ A;  2UXC H;  4OX9 H;  2VQE H;  2P2R A;  2CTK A;  2X06 A;  4QMF B;  4LFA H;  4X62 H;  4FJS A;  1N36 H;  1X9Z A;  1HNX H;  4OD6 A;  4LF4 H;  4B3S H;  1UG8 A;  4K0K H;  4YHH H;  2YQR A;  1VIG A;  1V9N A;  2LRR A;  2ZM6 H;  1XNR H;  4IFD G;  4JV5 H;  4OO1 G;  2HHH H;  5LMN H;  4DV3 H;  1HNZ H;  2UUC H;  4DUY H;  1NXU A;  2JEB I;  2QND A;  3I0P A;  4JI7 H;  2LTM A;  4H8A A;  4WAN A;  4JI5 H;  3KDK A;  4JYA H;  3T1H H;  4JI6 H;  3JAM W;  1ZZK A;  2ZQE A;  4FJU A;  4AIM A;  1DT4 A;  1DTJ A;  3UOE A;  1ZZI A;  1VBI A;  4E9J A;  3OTO H;  1S03 G;  1J4W A;  4LIJ A;  4NXN H;  1IBL H;  1N33 H;  4DR6 H;  5IT9 W;  2CTL A;  2LTL A;  3FAU A;  4X65 H;  5LMU H;  4BA2 I;  4JI2 H;  4DV1 H;  3OSS D;  2PT7 G;  4LF7 H;  4NZT M;  2FMR A;  1X0A A;  5A2Q W;  1VIH A;  4B8C D;  1TUA A;  5JEA G;  4AM3 A;  4DR4 H;  5K36 G;  3J7A K;  2LF0 A;  4JVH A;  1S20 A;  1F0X A;  2MJH A;  1XNQ H;  2CTF A;  4WAL A;  4LF9 H;  1V8C A;  3T1Y H;  1J5K A;  4DR7 H;  1IBM H;  2UXB H;  5IWA H;  2CWF A;  1SEI A;  2CWH A;  4NZR M;  1X4N A;  4DR2 H;  5BR8 H;  1PQX A;  3OET A;  1XMO H;  2HH2 A;  1K1G A;  3AEV B;  2UXD H;  4DV7 H;  4DUZ H;  1XRH A;  4DR3 H;  2Y3M A;  4AQY H;  1I94 H;  2F4V H;  2G8Y A;  1WTJ A;  5FLX W;  3RF2 A;  2D9I A;  2FFM A;  2M6Q A;  2ANR A;  3J80 W;  4JI3 H;  2NN6 G;  2JVZ A;  3GAB A;  2AXY A;  1XMQ H;  1Z2I A;  2CTE A;  2UUB H;  1FJG H;  1EC6 A;  1WE8 A;  1N34 H;  1ZTG A;  4LF5 H;  2E3U A;  2JE6 I;  2UUA H;  1WVN A;  2M8W A;  2O4C A;  3SB1 A;  4JI1 H;  4KHP H;  1HNW H;  4JVY A;  1X4M A;  4X66 H;  4DR1 H;  3QD7 X;  2DGR A;  4B3M H;  2K1H A;  4JI4 H;  5DT9 A;  2VQF H;  4GKJ H;  2CPQ A;  1ZZJ A;  4PDB A;  4OCH A;  4DR5 H;  1I6U A;  1ODH A;  2JZX A;  4B3R H;  1KHM A; 
#chains in the Genus database with same CATH homology
 2BA0 A;  2CTK A;  2CTM A;  4QMF B;  2CTL A;  4BA2 I;  2ANR A;  2NN6 G;  2JVZ A;  2AXY A;  2PY9 A;  2Z0S A;  2CTE A;  1VIG A;  2YQR A;  3V69 A;  4OO1 G;  1WE8 A;  1ZTG A;  4IFD G;  1EC6 A;  2FMR A;  2E3U A;  2JE6 I;  1VIH A;  1WVN A;  1TUA A;  2OPV A;  3L7Z C;  5JEA G;  4B8T A;  4AM3 A;  5K36 G;  5C0X G;  2JEB I;  2QND A;  4JVY A;  4WAN A;  1X4M A;  2JEA I;  4JVH A;  2HH3 A;  2OPU A;  2MJH A;  1ZZK A;  2CTJ A;  2CTF A;  2DGR A;  4NBQ A;  4AIM A;  4WAL A;  4BA1 I;  1DT4 A;  1DTJ A;  1J5K A;  1ZZI A;  3U1K A;  1X4N A;  3VKE A;  1J4W A;  1K1G A;  2CPQ A;  2HH2 A;  2JA9 A;  4LIJ A;  1ZZJ A;  2PQU A;  2ANN A;  3AEV B;  2BL5 A;  2JZX A;  1KHM A;  2P2R A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...