2OPU | Genus

Total Genus 24

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	24
sequence length	89
structure length	89
Chain Sequence	ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Rna binding protein
source organism	Homo sapiens
publication title	Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding. pubmed doi rcsb
molecule keywords	KHSRP protein
total genus	24
structure length	89
sequence length	89
ec nomenclature
pdb deposition date	2007-01-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00013	KH_1	KH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1370.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S8; Chain: A, domain 1	K Homology domain, type 1	2opuA00

2HH2A 1DTJA 2YQRA 4JVYA 2CPQA 1EC6A 3U1KA 5JEAG 2PQUA 2CTJA 4AM3A 1KHMA 2QNDA 4WANA 2HH3A 2CTFA 2E3UA 1X4MA 2Z0SA 1K1GA 2JZXA 2ANRA 2BA0A 2MJHA 2CTKA 2JVZA 2PY9A 4NBQA 2OPUA 1ZZJA 1J5KA 2P2RA 4B8TA 4OO1G 5K36G 2CTLA 2CTMA 2OPVA 2JEBI 1ZTGA 2JEAI 3L7ZC 1WE8A 3VKEA 2BL5A 1X4NA 2DGRA 4AIMA 1TUAA 2JE6I 2NN6G 4IFDG 3V69A 4WALA 2ANNA 3AEVB 4JVHA 1VIGA 1DT4A 5C0XG 1J4WA 4BA1I 4BA2I 1ZZIA 1WVNA 2JA9A 2FMRA 1ZZKA 1VIHA 4LIJA 4QMFB 2CTEA 2AXYA
chains in the Genus database with same CATH superfamily

1DTJA 2LF0A 1X9ZA 3J81W 2CPQA 1ODHA 1EC6A 4OD6A 4DV4H 4KHPH 1HNXH 2PT7G 2LRRA 2X06A 2QNDA 1N34H 4JV5H 2UUCH 5K36G 2ANRA 4FJSA 2CTKA 4AQYH 4LF4H 1IBKH 4DR1H 2PY9A 1S20A 4B3TH 4B3SH 4NXMH 2OPUA 3GABA 1J5KA 2UUBH 4DR2H 5LMNH 4B8TA 4LFAH 1Z2IA 2CTLA 2OPVA 4DUYH 2E5LH 3JAMW 3SB1A 4AIMA 1UG8A 2F4VH 1TUAA 2UXDH 4YHHH 4WALA 1XNQH 3KDKA 4JI3H 3EZJA 4DV3H 4BA1I 2UXCH 4K0KH 4YY3H 4LF6H 1IBLH 2M6QA 3OETA 2UU9H 4DR5H 2FFMA 2HH2A 1MSZA 2CWFA 2VQEH 3T1HH 2O4CA 4JI7H 3NCVA 2CTJA 4H8AA 4DR4H 4WANA 2CPMA 1X4MA 1K1GA 4JI8H 1WHRA 4DV7H 5A2QW 4G08A 1HR0H 1XNRH 2A1SA 1NXUA 3J7AK 2P2RA 4LF8H 4OX9H 2CTMA 3QD7X 1F0XA 1N33H 1J5EH 4JI5H 4NZTM 2DGRA 4X64H 2Y3MA 3KDGA 4DR6H 5BR8H 1HNZH 4JI4H 2JE6I 4JVHA 4EC5A 1DT4A 4JYAH 4GKJH 1X0AA 4DR7H 1I6UA 2M8WA 1V9NA 1VIHA 4QMFB 2ANNA 2AXYA 4X66H 4LF9H 4LFBH 2UXBH 2YQRA 3UOEA 3U1KA 1XMOH 1KHMA 3T1YH 4JI2H 2HH3A 2UUAH 2E3UA 2FPHX 2LTLA 4DUZH 3RF2A 5DT9A 1HNWH 4OCHA 2JVZA 4NBQA 2LTMA 3OSSD 4LF7H 4LF5H 2CWHA 1ZZJA 1WTJA 4X65H 1ZTGA 5IWAH 2JEAI 2G8YA 3L7ZC 1WE8A 4DR3H 2BL5A 1X4NA 4JI6H 5FLXW 3J80W 2NN6G 4IFDG 3AEVB 1I94H 1VIGA 1J4WA 3GR5A 4LFCH 4BA2I 1ZZIA 1WVNA 2JA9A 1FKAH 1ZZKA 1N32H 4LIJA 2CTEA 1S03G 4JVYA 1IBMH 1FJGH 5JEAG 3FAUA 2PQUA 4AM3A 1SEIA 3GKUA 2VKCA 2CTFA 2Z0SA 2JZXA 2MJHA 2BA0A 4JI0H 3I0PA 4DV2H 2ZM6H 1XMQH 2HHHH 1N36H 2K1HA 4E9JA 4B3MH 4X62H 4NXNH 3OTOH 4DV1H 4OO1G 2JEBI 2VQFH 3VKEA 4PDBA 1XRHA 4DV6H 4B3RH 4DV5H 4B8CD 3V69A 4JI1H 4GKKH 5C0XG 1V8CA 5LMUH 4NZRM 1AN7A 4DV0H 1PQXA 2FMRA 2D9IA 4FJUA 5IT9W 5LL6b 2ZQEA 1VBIA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2HH2 A;  1DTJ A;  2YQR A;  4JVY A;  2CPQ A;  1EC6 A;  3U1K A;  5JEA G;  2PQU A;  2CTJ A;  4AM3 A;  1KHM A;  2QND A;  4WAN A;  2HH3 A;  2CTF A;  2E3U A;  1X4M A;  2Z0S A;  1K1G A;  2JZX A;  2ANR A;  2BA0 A;  2MJH A;  2CTK A;  2JVZ A;  2PY9 A;  4NBQ A;  2OPU A;  1ZZJ A;  1J5K A;  2P2R A;  4B8T A;  4OO1 G;  5K36 G;  2CTL A;  2CTM A;  2OPV A;  2JEB I;  1ZTG A;  2JEA I;  3L7Z C;  1WE8 A;  3VKE A;  2BL5 A;  1X4N A;  2DGR A;  4AIM A;  1TUA A;  2JE6 I;  2NN6 G;  4IFD G;  3V69 A;  4WAL A;  2ANN A;  3AEV B;  4JVH A;  1VIG A;  1DT4 A;  5C0X G;  1J4W A;  4BA1 I;  4BA2 I;  1ZZI A;  1WVN A;  2JA9 A;  2FMR A;  1ZZK A;  1VIH A;  4LIJ A;  4QMF B;  2CTE A;  2AXY A; 
#chains in the Genus database with same CATH topology
 1DTJ A;  2LF0 A;  1X9Z A;  3J81 W;  2CPQ A;  1ODH A;  1EC6 A;  4OD6 A;  4DV4 H;  4KHP H;  1HNX H;  2PT7 G;  2LRR A;  2X06 A;  2QND A;  1N34 H;  4JV5 H;  2UUC H;  5K36 G;  2ANR A;  4FJS A;  2CTK A;  4AQY H;  4LF4 H;  1IBK H;  4DR1 H;  2PY9 A;  1S20 A;  4B3T H;  4B3S H;  4NXM H;  2OPU A;  3GAB A;  1J5K A;  2UUB H;  4DR2 H;  5LMN H;  4B8T A;  4LFA H;  1Z2I A;  2CTL A;  2OPV A;  4DUY H;  2E5L H;  3JAM W;  3SB1 A;  4AIM A;  1UG8 A;  2F4V H;  1TUA A;  2UXD H;  4YHH H;  4WAL A;  1XNQ H;  3KDK A;  4JI3 H;  3EZJ A;  4DV3 H;  4BA1 I;  2UXC H;  4K0K H;  4YY3 H;  4LF6 H;  1IBL H;  2M6Q A;  3OET A;  2UU9 H;  4DR5 H;  2FFM A;  2HH2 A;  1MSZ A;  2CWF A;  2VQE H;  3T1H H;  2O4C A;  4JI7 H;  3NCV A;  2CTJ A;  4H8A A;  4DR4 H;  4WAN A;  2CPM A;  1X4M A;  1K1G A;  4JI8 H;  1WHR A;  4DV7 H;  5A2Q W;  4G08 A;  1HR0 H;  1XNR H;  2A1S A;  1NXU A;  3J7A K;  2P2R A;  4LF8 H;  4OX9 H;  2CTM A;  3QD7 X;  1F0X A;  1N33 H;  1J5E H;  4JI5 H;  4NZT M;  2DGR A;  4X64 H;  2Y3M A;  3KDG A;  4DR6 H;  5BR8 H;  1HNZ H;  4JI4 H;  2JE6 I;  4JVH A;  4EC5 A;  1DT4 A;  4JYA H;  4GKJ H;  1X0A A;  4DR7 H;  1I6U A;  2M8W A;  1V9N A;  1VIH A;  4QMF B;  2ANN A;  2AXY A;  4X66 H;  4LF9 H;  4LFB H;  2UXB H;  2YQR A;  3UOE A;  3U1K A;  1XMO H;  1KHM A;  3T1Y H;  4JI2 H;  2HH3 A;  2UUA H;  2E3U A;  2FPH X;  2LTL A;  4DUZ H;  3RF2 A;  5DT9 A;  1HNW H;  4OCH A;  2JVZ A;  4NBQ A;  2LTM A;  3OSS D;  4LF7 H;  4LF5 H;  2CWH A;  1ZZJ A;  1WTJ A;  4X65 H;  1ZTG A;  5IWA H;  2JEA I;  2G8Y A;  3L7Z C;  1WE8 A;  4DR3 H;  2BL5 A;  1X4N A;  4JI6 H;  5FLX W;  3J80 W;  2NN6 G;  4IFD G;  3AEV B;  1I94 H;  1VIG A;  1J4W A;  3GR5 A;  4LFC H;  4BA2 I;  1ZZI A;  1WVN A;  2JA9 A;  1FKA H;  1ZZK A;  1N32 H;  4LIJ A;  2CTE A;  1S03 G;  4JVY A;  1IBM H;  1FJG H;  5JEA G;  3FAU A;  2PQU A;  4AM3 A;  1SEI A;  3GKU A;  2VKC A;  2CTF A;  2Z0S A;  2JZX A;  2MJH A;  2BA0 A;  4JI0 H;  3I0P A;  4DV2 H;  2ZM6 H;  1XMQ H;  2HHH H;  1N36 H;  2K1H A;  4E9J A;  4B3M H;  4X62 H;  4NXN H;  3OTO H;  4DV1 H;  4OO1 G;  2JEB I;  2VQF H;  3VKE A;  4PDB A;  1XRH A;  4DV6 H;  4B3R H;  4DV5 H;  4B8C D;  3V69 A;  4JI1 H;  4GKK H;  5C0X G;  1V8C A;  5LMU H;  4NZR M;  1AN7 A;  4DV0 H;  1PQX A;  2FMR A;  2D9I A;  4FJU A;  5IT9 W;  5LL6 b;  2ZQE A;  1VBI A; 
#chains in the Genus database with same CATH homology
 2HH2 A;  1DTJ A;  2YQR A;  4JVY A;  2CPQ A;  1EC6 A;  3U1K A;  5JEA G;  2PQU A;  2CTJ A;  4AM3 A;  1KHM A;  2QND A;  4WAN A;  2HH3 A;  2CTF A;  2E3U A;  1X4M A;  2Z0S A;  1K1G A;  2JZX A;  2ANR A;  2BA0 A;  2MJH A;  2CTK A;  2JVZ A;  2PY9 A;  4NBQ A;  2OPU A;  1ZZJ A;  1J5K A;  2P2R A;  4B8T A;  4OO1 G;  5K36 G;  2CTL A;  2CTM A;  2OPV A;  2JEB I;  1ZTG A;  2JEA I;  3L7Z C;  1WE8 A;  3VKE A;  2BL5 A;  1X4N A;  2DGR A;  4AIM A;  1TUA A;  2JE6 I;  2NN6 G;  4IFD G;  3V69 A;  4WAL A;  2ANN A;  3AEV B;  4JVH A;  1VIG A;  1DT4 A;  5C0X G;  1J4W A;  4BA1 I;  4BA2 I;  1ZZI A;  1WVN A;  2JA9 A;  2FMR A;  1ZZK A;  1VIH A;  4LIJ A;  4QMF B;  2CTE A;  2AXY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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2OPUA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations