2PQUA

Crystal structure of kh1 domain of human pcbp2 complexed to single-stranded 12-mer telomeric dna
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
72
structure length
72
Chain Sequence
KNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2.
pubmed doi rcsb
molecule tags Rna and dna binding protein/dna
source organism Homo sapiens
molecule keywords 12-mer C-rich strand of human telomeric DNA
total genus 17
structure length 72
sequence length 72
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2007-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2pquA00
5C0XG 1TUAA 2CTLA 2E3UA 1WE8A 2OPUA 2QNDA 2Z0SA 3U1KA 2ANNA 2YQRA 4LIJA 2PY9A 4BA2I 1VIGA 4AM3A 2BA0A 2CTEA 4NBQA 2MJHA 1J5KA 4WALA 3VKEA 1X4MA 1ZZIA 2ANRA 4IFDG 1ZZKA 2PQUA 1ZZJA 2AXYA 2CTFA 2FMRA 1DT4A 2HH3A 2JZXA 5JEAG 1VIHA 4JVHA 5K36G 4QMFB 3V69A 2OPVA 2CTMA 2JEBI 4AIMA 4OO1G 1X4NA 2JEAI 4B8TA 2HH2A 2CPQA 3AEVB 3L7ZC 2CTJA 1WVNA 2DGRA 1J4WA 1K1GA 1ZTGA 2P2RA 4WANA 1DTJA 2JA9A 2JE6I 1EC6A 2CTKA 4JVYA 2NN6G 4BA1I 1KHMA 2BL5A 2JVZA
chains in the Genus database with same CATH superfamily
1I94H 1HNXH 2M8WA 2ZQEA 1N33H 1TUAA 3U1KA 1VIGA 1ODHA 4B3SH 2UXDH 1S03G 4JI5H 4X62H 1WTJA 3VKEA 1X4MA 4FJUA 2PQUA 2ZM6H 1WHRA 2FMRA 4DR7H 2Y3MA 1DT4A 2JZXA 4GKKH 5JEAG 1VIHA 5K36G 3OTOH 4KHPH 5A2QW 1AN7A 3JAMW 2CTMA 5BR8H 2JEBI 4AIMA 5LL6b 4YHHH 4B3RH 2HH2A 2CPQA 5FLXW 1FKAH 3AEVB 1WVNA 4NXNH 4X65H 1XMQH 4DV4H 1DTJA 5IT9W 4JI2H 4BA1I 3OSSD 1N32H 4JV5H 4FJSA 4LF5H 4JI6H 2E3UA 3KDKA 2Z0SA 1HNWH 1I6UA 2YQRA 3SB1A 3T1YH 2ANNA 2PY9A 4X66H 2BA0A 2CTEA 4NBQA 4BA2I 4AM3A 1J5KA 4LFBH 4WALA 1ZZIA 1IBMH 4DR6H 4NZTM 1ZZJA 1V8CA 3UOEA 4JYAH 3V69A 2OPVA 4DR1H 5DT9A 4OO1G 3EZJA 4B3TH 1IBKH 2CTJA 2DGRA 4DR4H 1K1GA 1HNZH 4NXMH 2A1SA 4DV7H 2UU9H 2VQEH 1X0AA 4LF9H 1J5EH 3FAUA 2CWHA 1X9ZA 4YY3H 4E9JA 3J81W 3T1HH 2CTLA 2QNDA 1WE8A 4B8CD 4LF7H 4DV1H 1SEIA 3GKUA 2X06A 3I0PA 4LIJA 1F0XA 3J80W 5LMUH 4DUZH 2MJHA 2UUCH 4DV5H 2LRRA 4PDBA 1ZZKA 2K1HA 4LFAH 4JI0H 2CTFA 4JI7H 3NCVA 3QD7X 1HR0H 2UXBH 2D9IA 2FPHX 1UG8A 4QMFB 2UUBH 4DV0H 2E5LH 2O4CA 4LF4H 2LTMA 1X4NA 2JEAI 2G8YA 1XMOH 4GKJH 2UUAH 4B8TA 1IBLH 2FFMA 4H8AA 1J4WA 1ZTGA 2P2RA 4WANA 1V9NA 2JE6I 2CTKA 1XNRH 2ANRA 1KHMA 2BL5A 1MSZA 2CPMA 1N36H 1Z2IA 5C0XG 1FJGH 4DV3H 2OPUA 4JI4H 4JVHA 4JI3H 4JI8H 4DV2H 4LF8H 4DV6H 4DR3H 4NZRM 4EC5A 4LF6H 4DR5H 2M6QA 4DR2H 4IFDG 4AQYH 1XRHA 2AXYA 4OX9H 2LTLA 2HH3A 1PQXA 4X64H 2HHHH 1S20A 3GABA 3KDGA 4OCHA 5IWAH 1NXUA 2PT7G 3GR5A 3RF2A 2LF0A 4G08A 3OETA 4K0KH 2VQFH 3J7AK 4LFCH 3L7ZC 4OD6A 4B3MH 5LMNH 1N34H 2F4VH 2JA9A 1XNQH 1EC6A 2VKCA 4JI1H 4JVYA 4DUYH 2NN6G 2UXCH 2CWFA 1VBIA 2JVZA
chains in the Genus database with same CATH topology
5C0XG 1TUAA 2CTLA 2E3UA 1WE8A 2OPUA 2QNDA 2Z0SA 3U1KA 2ANNA 2YQRA 4LIJA 2PY9A 4BA2I 1VIGA 4AM3A 2BA0A 2CTEA 4NBQA 2MJHA 1J5KA 4WALA 3VKEA 1X4MA 1ZZIA 2ANRA 4IFDG 1ZZKA 2PQUA 1ZZJA 2AXYA 2CTFA 2FMRA 1DT4A 2HH3A 2JZXA 5JEAG 1VIHA 4JVHA 5K36G 4QMFB 3V69A 2OPVA 2CTMA 2JEBI 4AIMA 4OO1G 1X4NA 2JEAI 4B8TA 2HH2A 2CPQA 3AEVB 3L7ZC 2CTJA 1WVNA 2DGRA 1J4WA 1K1GA 1ZTGA 2P2RA 4WANA 1DTJA 2JA9A 2JE6I 1EC6A 2CTKA 4JVYA 2NN6G 4BA1I 1KHMA 2BL5A 2JVZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C0X G;  1TUA A;  2CTL A;  2E3U A;  1WE8 A;  2OPU A;  2QND A;  2Z0S A;  3U1K A;  2ANN A;  2YQR A;  4LIJ A;  2PY9 A;  4BA2 I;  1VIG A;  4AM3 A;  2BA0 A;  2CTE A;  4NBQ A;  2MJH A;  1J5K A;  4WAL A;  3VKE A;  1X4M A;  1ZZI A;  2ANR A;  4IFD G;  1ZZK A;  2PQU A;  1ZZJ A;  2AXY A;  2CTF A;  2FMR A;  1DT4 A;  2HH3 A;  2JZX A;  5JEA G;  1VIH A;  4JVH A;  5K36 G;  4QMF B;  3V69 A;  2OPV A;  2CTM A;  2JEB I;  4AIM A;  4OO1 G;  1X4N A;  2JEA I;  4B8T A;  2HH2 A;  2CPQ A;  3AEV B;  3L7Z C;  2CTJ A;  1WVN A;  2DGR A;  1J4W A;  1K1G A;  1ZTG A;  2P2R A;  4WAN A;  1DTJ A;  2JA9 A;  2JE6 I;  1EC6 A;  2CTK A;  4JVY A;  2NN6 G;  4BA1 I;  1KHM A;  2BL5 A;  2JVZ A; 
#chains in the Genus database with same CATH topology
 1I94 H;  1HNX H;  2M8W A;  2ZQE A;  1N33 H;  1TUA A;  3U1K A;  1VIG A;  1ODH A;  4B3S H;  2UXD H;  1S03 G;  4JI5 H;  4X62 H;  1WTJ A;  3VKE A;  1X4M A;  4FJU A;  2PQU A;  2ZM6 H;  1WHR A;  2FMR A;  4DR7 H;  2Y3M A;  1DT4 A;  2JZX A;  4GKK H;  5JEA G;  1VIH A;  5K36 G;  3OTO H;  4KHP H;  5A2Q W;  1AN7 A;  3JAM W;  2CTM A;  5BR8 H;  2JEB I;  4AIM A;  5LL6 b;  4YHH H;  4B3R H;  2HH2 A;  2CPQ A;  5FLX W;  1FKA H;  3AEV B;  1WVN A;  4NXN H;  4X65 H;  1XMQ H;  4DV4 H;  1DTJ A;  5IT9 W;  4JI2 H;  4BA1 I;  3OSS D;  1N32 H;  4JV5 H;  4FJS A;  4LF5 H;  4JI6 H;  2E3U A;  3KDK A;  2Z0S A;  1HNW H;  1I6U A;  2YQR A;  3SB1 A;  3T1Y H;  2ANN A;  2PY9 A;  4X66 H;  2BA0 A;  2CTE A;  4NBQ A;  4BA2 I;  4AM3 A;  1J5K A;  4LFB H;  4WAL A;  1ZZI A;  1IBM H;  4DR6 H;  4NZT M;  1ZZJ A;  1V8C A;  3UOE A;  4JYA H;  3V69 A;  2OPV A;  4DR1 H;  5DT9 A;  4OO1 G;  3EZJ A;  4B3T H;  1IBK H;  2CTJ A;  2DGR A;  4DR4 H;  1K1G A;  1HNZ H;  4NXM H;  2A1S A;  4DV7 H;  2UU9 H;  2VQE H;  1X0A A;  4LF9 H;  1J5E H;  3FAU A;  2CWH A;  1X9Z A;  4YY3 H;  4E9J A;  3J81 W;  3T1H H;  2CTL A;  2QND A;  1WE8 A;  4B8C D;  4LF7 H;  4DV1 H;  1SEI A;  3GKU A;  2X06 A;  3I0P A;  4LIJ A;  1F0X A;  3J80 W;  5LMU H;  4DUZ H;  2MJH A;  2UUC H;  4DV5 H;  2LRR A;  4PDB A;  1ZZK A;  2K1H A;  4LFA H;  4JI0 H;  2CTF A;  4JI7 H;  3NCV A;  3QD7 X;  1HR0 H;  2UXB H;  2D9I A;  2FPH X;  1UG8 A;  4QMF B;  2UUB H;  4DV0 H;  2E5L H;  2O4C A;  4LF4 H;  2LTM A;  1X4N A;  2JEA I;  2G8Y A;  1XMO H;  4GKJ H;  2UUA H;  4B8T A;  1IBL H;  2FFM A;  4H8A A;  1J4W A;  1ZTG A;  2P2R A;  4WAN A;  1V9N A;  2JE6 I;  2CTK A;  1XNR H;  2ANR A;  1KHM A;  2BL5 A;  1MSZ A;  2CPM A;  1N36 H;  1Z2I A;  5C0X G;  1FJG H;  4DV3 H;  2OPU A;  4JI4 H;  4JVH A;  4JI3 H;  4JI8 H;  4DV2 H;  4LF8 H;  4DV6 H;  4DR3 H;  4NZR M;  4EC5 A;  4LF6 H;  4DR5 H;  2M6Q A;  4DR2 H;  4IFD G;  4AQY H;  1XRH A;  2AXY A;  4OX9 H;  2LTL A;  2HH3 A;  1PQX A;  4X64 H;  2HHH H;  1S20 A;  3GAB A;  3KDG A;  4OCH A;  5IWA H;  1NXU A;  2PT7 G;  3GR5 A;  3RF2 A;  2LF0 A;  4G08 A;  3OET A;  4K0K H;  2VQF H;  3J7A K;  4LFC H;  3L7Z C;  4OD6 A;  4B3M H;  5LMN H;  1N34 H;  2F4V H;  2JA9 A;  1XNQ H;  1EC6 A;  2VKC A;  4JI1 H;  4JVY A;  4DUY H;  2NN6 G;  2UXC H;  2CWF A;  1VBI A;  2JVZ A; 
#chains in the Genus database with same CATH homology
 5C0X G;  1TUA A;  2CTL A;  2E3U A;  1WE8 A;  2OPU A;  2QND A;  2Z0S A;  3U1K A;  2ANN A;  2YQR A;  4LIJ A;  2PY9 A;  4BA2 I;  1VIG A;  4AM3 A;  2BA0 A;  2CTE A;  4NBQ A;  2MJH A;  1J5K A;  4WAL A;  3VKE A;  1X4M A;  1ZZI A;  2ANR A;  4IFD G;  1ZZK A;  2PQU A;  1ZZJ A;  2AXY A;  2CTF A;  2FMR A;  1DT4 A;  2HH3 A;  2JZX A;  5JEA G;  1VIH A;  4JVH A;  5K36 G;  4QMF B;  3V69 A;  2OPV A;  2CTM A;  2JEB I;  4AIM A;  4OO1 G;  1X4N A;  2JEA I;  4B8T A;  2HH2 A;  2CPQ A;  3AEV B;  3L7Z C;  2CTJ A;  1WVN A;  2DGR A;  1J4W A;  1K1G A;  1ZTG A;  2P2R A;  4WAN A;  1DTJ A;  2JA9 A;  2JE6 I;  1EC6 A;  2CTK A;  4JVY A;  2NN6 G;  4BA1 I;  1KHM A;  2BL5 A;  2JVZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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