2PQUA

Crystal structure of kh1 domain of human pcbp2 complexed to single-stranded 12-mer telomeric dna
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
72
structure length
72
Chain Sequence
KNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2.
pubmed doi rcsb
molecule tags Rna and dna binding protein/dna
source organism Homo sapiens
molecule keywords 12-mer C-rich strand of human telomeric DNA
total genus 17
structure length 72
sequence length 72
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2007-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2pquA00
1TUAA 3U1KA 2E3UA 2CPQA 2BL5A 2CTFA 1DT4A 1ZZKA 4LIJA 1ZZJA 2JEBI 2P2RA 2CTJA 1WVNA 5C0XG 1K1GA 2JEAI 4AM3A 1VIGA 1VIHA 2BA0A 1WE8A 2OPUA 1ZTGA 1EC6A 4JVYA 1X4MA 2CTLA 4AIMA 2AXYA 1KHMA 4QMFB 5JEAG 2PY9A 4WALA 3AEVB 4IFDG 2JE6I 1ZZIA 2JA9A 2Z0SA 2JZXA 2ANRA 2QNDA 4B8TA 2PQUA 2JVZA 4BA1I 1DTJA 4WANA 2CTEA 2CTMA 3V69A 2ANNA 4OO1G 3L7ZC 4JVHA 2YQRA 2OPVA 1X4NA 3VKEA 2CTKA 1J5KA 2DGRA 1J4WA 2FMRA 2HH2A 2MJHA 5K36G 4BA2I 2NN6G 4NBQA 2HH3A
chains in the Genus database with same CATH superfamily
1TUAA 1IBLH 4YY3H 2E3UA 4LFAH 4JI3H 4DR6H 4JYAH 4DR1H 4LF6H 1XRHA 3KDGA 2P2RA 3KDKA 2UU9H 1XNQH 1Z2IA 4DR7H 2BA0A 1WE8A 3GABA 4DV5H 2ZM6H 1KHMA 2CTLA 4DV2H 1AN7A 3SB1A 3OTOH 2PY9A 1S20A 1X9ZA 2CWHA 4JI5H 4DV6H 2JZXA 4X64H 2QNDA 4B8TA 3QD7X 1I6UA 4X65H 4DR5H 4DR2H 2O4CA 2CTKA 4JI8H 2DGRA 4PDBA 2ZQEA 2LTMA 4JI4H 1N33H 5A2QW 4B3MH 4JI0H 4DR3H 5K36G 3J81W 1ODHA 2HH3A 1S03G 4G08A 2CPQA 1DT4A 2G8YA 5DT9A 4JI1H 4GKJH 2JEBI 4LF5H 4LF7H 1WVNA 5IT9W 4AM3A 4FJUA 1VIGA 2A1SA 4DR4H 2OPUA 4DV3H 4LFBH 2X06A 2VKCA 2AXYA 1V9NA 4DUZH 4QMFB 5JEAG 2E5LH 4B3SH 2M8WA 4LF9H 4DV0H 1ZZIA 4X62H 4OCHA 2Z0SA 2ANRA 2Y3MA 1HNZH 4BA1I 4AQYH 3GR5A 1IBMH 4JI6H 2UUBH 1X4NA 4DV1H 1WTJA 1FKAH 4NXMH 2LTLA 1J5EH 4LFCH 1SEIA 4OD6A 4FJSA 5LMNH 1I94H 3J7AK 4NBQA 4E9JA 1HNWH 3I0PA 5FLXW 2D9IA 4GKKH 2BL5A 1NXUA 2CTFA 4EC5A 3T1YH 1XNRH 1WHRA 2UUAH 3OETA 1ZZKA 4DV4H 2CTJA 4NZTM 1XMOH 1VIHA 1ZTGA 1EC6A 4JVYA 3AEVB 4WALA 2JE6I 2PT7G 3EZJA 3GKUA 2JA9A 5BR8H 5LL6b 1V8CA 2JVZA 2PQUA 4WANA 2CTEA 3V69A 2ANNA 4JVHA 4OO1G 1UG8A 2YQRA 2CPMA 1MSZA 2HHHH 3VKEA 2M6QA 2K1HA 1J5KA 2LRRA 5IWAH 1IBKH 1J4WA 1X0AA 2FMRA 2CWFA 4H8AA 2F4VH 2FFMA 4BA2I 1FJGH 1XMQH 3U1KA 4OX9H 3JAMW 4LF4H 1HR0H 4X66H 1N32H 4B3TH 4LIJA 1ZZJA 4JI7H 5C0XG 1K1GA 2JEAI 4JV5H 2FPHX 2UUCH 3UOEA 3NCVA 4DUYH 1X4MA 4AIMA 2UXDH 4YHHH 4B8CD 1F0XA 3T1HH 4IFDG 3OSSD 5LMUH 1N34H 2VQFH 1DTJA 2CTMA 4K0KH 1N36H 3L7ZC 4NZRM 2UXBH 2UXCH 4NXNH 2OPVA 3J80W 2LF0A 4JI2H 3FAUA 4DV7H 4B3RH 3RF2A 1PQXA 2HH2A 2VQEH 4KHPH 1HNXH 2MJHA 4LF8H 1VBIA 2NN6G
chains in the Genus database with same CATH topology
1TUAA 3U1KA 2E3UA 2CPQA 2BL5A 2CTFA 1DT4A 1ZZKA 4LIJA 1ZZJA 2JEBI 2P2RA 2CTJA 1WVNA 5C0XG 1K1GA 2JEAI 4AM3A 1VIGA 1VIHA 2BA0A 1WE8A 2OPUA 1ZTGA 1EC6A 4JVYA 1X4MA 2CTLA 4AIMA 2AXYA 1KHMA 4QMFB 5JEAG 2PY9A 4WALA 3AEVB 4IFDG 2JE6I 1ZZIA 2JA9A 2Z0SA 2JZXA 2ANRA 2QNDA 4B8TA 2PQUA 2JVZA 4BA1I 1DTJA 4WANA 2CTEA 2CTMA 3V69A 2ANNA 4OO1G 3L7ZC 4JVHA 2YQRA 2OPVA 1X4NA 3VKEA 2CTKA 1J5KA 2DGRA 1J4WA 2FMRA 2HH2A 2MJHA 5K36G 4BA2I 2NN6G 4NBQA 2HH3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TUA A;  3U1K A;  2E3U A;  2CPQ A;  2BL5 A;  2CTF A;  1DT4 A;  1ZZK A;  4LIJ A;  1ZZJ A;  2JEB I;  2P2R A;  2CTJ A;  1WVN A;  5C0X G;  1K1G A;  2JEA I;  4AM3 A;  1VIG A;  1VIH A;  2BA0 A;  1WE8 A;  2OPU A;  1ZTG A;  1EC6 A;  4JVY A;  1X4M A;  2CTL A;  4AIM A;  2AXY A;  1KHM A;  4QMF B;  5JEA G;  2PY9 A;  4WAL A;  3AEV B;  4IFD G;  2JE6 I;  1ZZI A;  2JA9 A;  2Z0S A;  2JZX A;  2ANR A;  2QND A;  4B8T A;  2PQU A;  2JVZ A;  4BA1 I;  1DTJ A;  4WAN A;  2CTE A;  2CTM A;  3V69 A;  2ANN A;  4OO1 G;  3L7Z C;  4JVH A;  2YQR A;  2OPV A;  1X4N A;  3VKE A;  2CTK A;  1J5K A;  2DGR A;  1J4W A;  2FMR A;  2HH2 A;  2MJH A;  5K36 G;  4BA2 I;  2NN6 G;  4NBQ A;  2HH3 A; 
#chains in the Genus database with same CATH topology
 1TUA A;  1IBL H;  4YY3 H;  2E3U A;  4LFA H;  4JI3 H;  4DR6 H;  4JYA H;  4DR1 H;  4LF6 H;  1XRH A;  3KDG A;  2P2R A;  3KDK A;  2UU9 H;  1XNQ H;  1Z2I A;  4DR7 H;  2BA0 A;  1WE8 A;  3GAB A;  4DV5 H;  2ZM6 H;  1KHM A;  2CTL A;  4DV2 H;  1AN7 A;  3SB1 A;  3OTO H;  2PY9 A;  1S20 A;  1X9Z A;  2CWH A;  4JI5 H;  4DV6 H;  2JZX A;  4X64 H;  2QND A;  4B8T A;  3QD7 X;  1I6U A;  4X65 H;  4DR5 H;  4DR2 H;  2O4C A;  2CTK A;  4JI8 H;  2DGR A;  4PDB A;  2ZQE A;  2LTM A;  4JI4 H;  1N33 H;  5A2Q W;  4B3M H;  4JI0 H;  4DR3 H;  5K36 G;  3J81 W;  1ODH A;  2HH3 A;  1S03 G;  4G08 A;  2CPQ A;  1DT4 A;  2G8Y A;  5DT9 A;  4JI1 H;  4GKJ H;  2JEB I;  4LF5 H;  4LF7 H;  1WVN A;  5IT9 W;  4AM3 A;  4FJU A;  1VIG A;  2A1S A;  4DR4 H;  2OPU A;  4DV3 H;  4LFB H;  2X06 A;  2VKC A;  2AXY A;  1V9N A;  4DUZ H;  4QMF B;  5JEA G;  2E5L H;  4B3S H;  2M8W A;  4LF9 H;  4DV0 H;  1ZZI A;  4X62 H;  4OCH A;  2Z0S A;  2ANR A;  2Y3M A;  1HNZ H;  4BA1 I;  4AQY H;  3GR5 A;  1IBM H;  4JI6 H;  2UUB H;  1X4N A;  4DV1 H;  1WTJ A;  1FKA H;  4NXM H;  2LTL A;  1J5E H;  4LFC H;  1SEI A;  4OD6 A;  4FJS A;  5LMN H;  1I94 H;  3J7A K;  4NBQ A;  4E9J A;  1HNW H;  3I0P A;  5FLX W;  2D9I A;  4GKK H;  2BL5 A;  1NXU A;  2CTF A;  4EC5 A;  3T1Y H;  1XNR H;  1WHR A;  2UUA H;  3OET A;  1ZZK A;  4DV4 H;  2CTJ A;  4NZT M;  1XMO H;  1VIH A;  1ZTG A;  1EC6 A;  4JVY A;  3AEV B;  4WAL A;  2JE6 I;  2PT7 G;  3EZJ A;  3GKU A;  2JA9 A;  5BR8 H;  5LL6 b;  1V8C A;  2JVZ A;  2PQU A;  4WAN A;  2CTE A;  3V69 A;  2ANN A;  4JVH A;  4OO1 G;  1UG8 A;  2YQR A;  2CPM A;  1MSZ A;  2HHH H;  3VKE A;  2M6Q A;  2K1H A;  1J5K A;  2LRR A;  5IWA H;  1IBK H;  1J4W A;  1X0A A;  2FMR A;  2CWF A;  4H8A A;  2F4V H;  2FFM A;  4BA2 I;  1FJG H;  1XMQ H;  3U1K A;  4OX9 H;  3JAM W;  4LF4 H;  1HR0 H;  4X66 H;  1N32 H;  4B3T H;  4LIJ A;  1ZZJ A;  4JI7 H;  5C0X G;  1K1G A;  2JEA I;  4JV5 H;  2FPH X;  2UUC H;  3UOE A;  3NCV A;  4DUY H;  1X4M A;  4AIM A;  2UXD H;  4YHH H;  4B8C D;  1F0X A;  3T1H H;  4IFD G;  3OSS D;  5LMU H;  1N34 H;  2VQF H;  1DTJ A;  2CTM A;  4K0K H;  1N36 H;  3L7Z C;  4NZR M;  2UXB H;  2UXC H;  4NXN H;  2OPV A;  3J80 W;  2LF0 A;  4JI2 H;  3FAU A;  4DV7 H;  4B3R H;  3RF2 A;  1PQX A;  2HH2 A;  2VQE H;  4KHP H;  1HNX H;  2MJH A;  4LF8 H;  1VBI A;  2NN6 G; 
#chains in the Genus database with same CATH homology
 1TUA A;  3U1K A;  2E3U A;  2CPQ A;  2BL5 A;  2CTF A;  1DT4 A;  1ZZK A;  4LIJ A;  1ZZJ A;  2JEB I;  2P2R A;  2CTJ A;  1WVN A;  5C0X G;  1K1G A;  2JEA I;  4AM3 A;  1VIG A;  1VIH A;  2BA0 A;  1WE8 A;  2OPU A;  1ZTG A;  1EC6 A;  4JVY A;  1X4M A;  2CTL A;  4AIM A;  2AXY A;  1KHM A;  4QMF B;  5JEA G;  2PY9 A;  4WAL A;  3AEV B;  4IFD G;  2JE6 I;  1ZZI A;  2JA9 A;  2Z0S A;  2JZX A;  2ANR A;  2QND A;  4B8T A;  2PQU A;  2JVZ A;  4BA1 I;  1DTJ A;  4WAN A;  2CTE A;  2CTM A;  3V69 A;  2ANN A;  4OO1 G;  3L7Z C;  4JVH A;  2YQR A;  2OPV A;  1X4N A;  3VKE A;  2CTK A;  1J5K A;  2DGR A;  1J4W A;  2FMR A;  2HH2 A;  2MJH A;  5K36 G;  4BA2 I;  2NN6 G;  4NBQ A;  2HH3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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