2QND | Genus

Total Genus 44

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	44
sequence length	141
structure length	141
Chain Sequence	FHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEGMVPFVFVGTKDSIANATVLLDYHLNYLK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Rna binding protein
source organism	Homo sapiens
publication title	Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein. pubmed doi rcsb
molecule keywords	FMR1 protein
total genus	44
structure length	141
sequence length	141
chains with identical sequence	B
ec nomenclature
pdb deposition date	2007-07-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00013	KH_1	KH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1370.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S8; Chain: A, domain 1	K Homology domain, type 1	2qndA02
3.30.1370.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S8; Chain: A, domain 1	K Homology domain, type 1	2qndA01

1WVNA 1ZZIA 2NN6G 1X4NA 2CTFA 4B8TA 4NBQA 2YQRA 2JE6I 2QNDA 2OPVA 2BL5A 2DGRA 2CTKA 4IFDG 4OO1G 2HH3A 2CTLA 1ZZKA 2AXYA 2CTMA 2CPQA 2CTEA 1TUAA 2E3UA 3U1KA 2ANNA 5K36G 2JVZA 3L7ZC 2BA0A 2JEAI 2FMRA 4QMFB 2PQUA 2MJHA 2JZXA 1K1GA 1KHMA 3VKEA 1VIGA 4BA1I 2CTJA 1DT4A 5C0XG 4WALA 4BA2I 4AM3A 1ZZJA 2OPUA 4LIJA 2JEBI 1J5KA 1EC6A 1WE8A 4JVYA 1X4MA 1ZTGA 2JA9A 2Z0SA 3V69A 2PY9A 1DTJA 4JVHA 1J4WA 2HH2A 3AEVB 2ANRA 2P2RA 4AIMA 4WANA 5JEAG 1VIHA
chains in the Genus database with same CATH superfamily

2CTFA 4B8TA 4LF7H 1I6UA 2YQRA 1HNZH 2OPVA 3OSSD 1I94H 4OX9H 2CTKA 4FJSA 2VQFH 2HH3A 1V9NA 4DV5H 1S20A 2CTLA 2LTLA 2AXYA 4YY3H 2A1SA 4X65H 5K36G 1NXUA 1SEIA 3GR5A 2JEAI 2UXBH 1VBIA 4LF5H 2G8YA 5C0XG 1DT4A 4WALA 4X66H 4AM3A 3KDGA 4NXNH 4DR7H 1EC6A 4JI3H 1N33H 4DR3H 4AQYH 2UUBH 4JI2H 4B3TH 4JVYA 2ZQEA 1X4MA 1XRHA 2JA9A 4FJUA 3V69A 4DUYH 1J5EH 2UUCH 2PY9A 4DR4H 3RF2A 2Y3MA 4AIMA 1WVNA 2NN6G 1X4NA 4NBQA 2CWFA 3SB1A 2QNDA 4DR5H 4LF8H 2FFMA 2M8WA 4H8AA 1X9ZA 1XMOH 5LMNH 4LFAH 2ANNA 3U1KA 5LL6b 4OD6A 5LMUH 2JVZA 3L7ZC 4JV5H 2FPHX 4X64H 2FMRA 4DV7H 1N34H 3KDKA 1VIGA 4BA1I 4B3SH 4NXMH 5A2QW 2UXCH 2OPUA 1V8CA 1MSZA 4LIJA 4OCHA 1J5KA 1HNXH 1IBMH 4JI0H 1S03G 2UU9H 3J7AK 2UXDH 2CPMA 2PT7G 4PDBA 2D9IA 4DR2H 2HH2A 4JI5H 3JAMW 4WANA 1ZZIA 1Z2IA 1FKAH 3QD7X 3GABA 4LFBH 2E5LH 4JI7H 2JE6I 2LTMA 3EZJA 2BL5A 3I0PA 4JYAH 1ZZKA 1UG8A 1WTJA 2CPQA 2CTMA 5IT9W 1WHRA 5BR8H 2VKCA 2BA0A 4DV2H 2K1HA 4QMFB 2MJHA 2O4CA 1K1GA 3VKEA 2LF0A 1XNQH 4JI6H 4DV0H 4K0KH 4B3RH 3NCVA 1WE8A 1XMQH 4B8CD 4JI1H 1FJGH 5IWAH 1DTJA 4DR1H 3AEVB 2ANRA 4DV6H 2P2RA 5JEAG 1IBLH 4NZTM 2PQUA 4DV1H 4GKJH 4X62H 4JI8H 1X0AA 2HHHH 2DGRA 1AN7A 4EC5A 2M6QA 2ZM6H 1IBKH 1PQXA 4E9JA 4IFDG 4LF9H 4OO1G 4DV3H 4DR6H 5FLXW 4LF6H 2CTEA 2E3UA 1TUAA 4NZRM 4JI4H 4LF4H 1XNRH 3T1YH 2VQEH 1ODHA 3OETA 1N32H 2JZXA 4LFCH 1KHMA 4YHHH 3J81W 2CTJA 2LRRA 4BA2I 4B3MH 1ZZJA 3OTOH 4GKKH 4KHPH 2UUAH 2JEBI 3FAUA 1F0XA 3GKUA 4G08A 3UOEA 4DUZH 4DV4H 1N36H 5DT9A 1HNWH 3T1HH 1HR0H 1ZTGA 2X06A 2Z0SA 3J80W 4JVHA 1J4WA 2F4VH 2CWHA 1VIHA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1WVN A;  1ZZI A;  2NN6 G;  1X4N A;  2CTF A;  4B8T A;  4NBQ A;  2YQR A;  2JE6 I;  2QND A;  2OPV A;  2BL5 A;  2DGR A;  2CTK A;  4IFD G;  4OO1 G;  2HH3 A;  2CTL A;  1ZZK A;  2AXY A;  2CTM A;  2CPQ A;  2CTE A;  1TUA A;  2E3U A;  3U1K A;  2ANN A;  5K36 G;  2JVZ A;  3L7Z C;  2BA0 A;  2JEA I;  2FMR A;  4QMF B;  2PQU A;  2MJH A;  2JZX A;  1K1G A;  1KHM A;  3VKE A;  1VIG A;  4BA1 I;  2CTJ A;  1DT4 A;  5C0X G;  4WAL A;  4BA2 I;  4AM3 A;  1ZZJ A;  2OPU A;  4LIJ A;  2JEB I;  1J5K A;  1EC6 A;  1WE8 A;  4JVY A;  1X4M A;  1ZTG A;  2JA9 A;  2Z0S A;  3V69 A;  2PY9 A;  1DTJ A;  4JVH A;  1J4W A;  2HH2 A;  3AEV B;  2ANR A;  2P2R A;  4AIM A;  4WAN A;  5JEA G;  1VIH A; 
#chains in the Genus database with same CATH topology
 2CTF A;  4B8T A;  4LF7 H;  1I6U A;  2YQR A;  1HNZ H;  2OPV A;  3OSS D;  1I94 H;  4OX9 H;  2CTK A;  4FJS A;  2VQF H;  2HH3 A;  1V9N A;  4DV5 H;  1S20 A;  2CTL A;  2LTL A;  2AXY A;  4YY3 H;  2A1S A;  4X65 H;  5K36 G;  1NXU A;  1SEI A;  3GR5 A;  2JEA I;  2UXB H;  1VBI A;  4LF5 H;  2G8Y A;  5C0X G;  1DT4 A;  4WAL A;  4X66 H;  4AM3 A;  3KDG A;  4NXN H;  4DR7 H;  1EC6 A;  4JI3 H;  1N33 H;  4DR3 H;  4AQY H;  2UUB H;  4JI2 H;  4B3T H;  4JVY A;  2ZQE A;  1X4M A;  1XRH A;  2JA9 A;  4FJU A;  3V69 A;  4DUY H;  1J5E H;  2UUC H;  2PY9 A;  4DR4 H;  3RF2 A;  2Y3M A;  4AIM A;  1WVN A;  2NN6 G;  1X4N A;  4NBQ A;  2CWF A;  3SB1 A;  2QND A;  4DR5 H;  4LF8 H;  2FFM A;  2M8W A;  4H8A A;  1X9Z A;  1XMO H;  5LMN H;  4LFA H;  2ANN A;  3U1K A;  5LL6 b;  4OD6 A;  5LMU H;  2JVZ A;  3L7Z C;  4JV5 H;  2FPH X;  4X64 H;  2FMR A;  4DV7 H;  1N34 H;  3KDK A;  1VIG A;  4BA1 I;  4B3S H;  4NXM H;  5A2Q W;  2UXC H;  2OPU A;  1V8C A;  1MSZ A;  4LIJ A;  4OCH A;  1J5K A;  1HNX H;  1IBM H;  4JI0 H;  1S03 G;  2UU9 H;  3J7A K;  2UXD H;  2CPM A;  2PT7 G;  4PDB A;  2D9I A;  4DR2 H;  2HH2 A;  4JI5 H;  3JAM W;  4WAN A;  1ZZI A;  1Z2I A;  1FKA H;  3QD7 X;  3GAB A;  4LFB H;  2E5L H;  4JI7 H;  2JE6 I;  2LTM A;  3EZJ A;  2BL5 A;  3I0P A;  4JYA H;  1ZZK A;  1UG8 A;  1WTJ A;  2CPQ A;  2CTM A;  5IT9 W;  1WHR A;  5BR8 H;  2VKC A;  2BA0 A;  4DV2 H;  2K1H A;  4QMF B;  2MJH A;  2O4C A;  1K1G A;  3VKE A;  2LF0 A;  1XNQ H;  4JI6 H;  4DV0 H;  4K0K H;  4B3R H;  3NCV A;  1WE8 A;  1XMQ H;  4B8C D;  4JI1 H;  1FJG H;  5IWA H;  1DTJ A;  4DR1 H;  3AEV B;  2ANR A;  4DV6 H;  2P2R A;  5JEA G;  1IBL H;  4NZT M;  2PQU A;  4DV1 H;  4GKJ H;  4X62 H;  4JI8 H;  1X0A A;  2HHH H;  2DGR A;  1AN7 A;  4EC5 A;  2M6Q A;  2ZM6 H;  1IBK H;  1PQX A;  4E9J A;  4IFD G;  4LF9 H;  4OO1 G;  4DV3 H;  4DR6 H;  5FLX W;  4LF6 H;  2CTE A;  2E3U A;  1TUA A;  4NZR M;  4JI4 H;  4LF4 H;  1XNR H;  3T1Y H;  2VQE H;  1ODH A;  3OET A;  1N32 H;  2JZX A;  4LFC H;  1KHM A;  4YHH H;  3J81 W;  2CTJ A;  2LRR A;  4BA2 I;  4B3M H;  1ZZJ A;  3OTO H;  4GKK H;  4KHP H;  2UUA H;  2JEB I;  3FAU A;  1F0X A;  3GKU A;  4G08 A;  3UOE A;  4DUZ H;  4DV4 H;  1N36 H;  5DT9 A;  1HNW H;  3T1H H;  1HR0 H;  1ZTG A;  2X06 A;  2Z0S A;  3J80 W;  4JVH A;  1J4W A;  2F4V H;  2CWH A;  1VIH A; 
#chains in the Genus database with same CATH homology
 1WVN A;  1ZZI A;  2NN6 G;  1X4N A;  2CTF A;  4B8T A;  4NBQ A;  2YQR A;  2JE6 I;  2QND A;  2OPV A;  2BL5 A;  2DGR A;  2CTK A;  4IFD G;  4OO1 G;  2HH3 A;  2CTL A;  1ZZK A;  2AXY A;  2CTM A;  2CPQ A;  2CTE A;  1TUA A;  2E3U A;  3U1K A;  2ANN A;  5K36 G;  2JVZ A;  3L7Z C;  2BA0 A;  2JEA I;  2FMR A;  4QMF B;  2PQU A;  2MJH A;  2JZX A;  1K1G A;  1KHM A;  3VKE A;  1VIG A;  4BA1 I;  2CTJ A;  1DT4 A;  5C0X G;  4WAL A;  4BA2 I;  4AM3 A;  1ZZJ A;  2OPU A;  4LIJ A;  2JEB I;  1J5K A;  1EC6 A;  1WE8 A;  4JVY A;  1X4M A;  1ZTG A;  2JA9 A;  2Z0S A;  3V69 A;  2PY9 A;  1DTJ A;  4JVH A;  1J4W A;  2HH2 A;  3AEV B;  2ANR A;  2P2R A;  4AIM A;  4WAN A;  5JEA G;  1VIH A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2QNDA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations