2QNDA

Crystal structure of the kh1-kh2 domains from human fragile x mental retardation protein
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
141
structure length
141
Chain Sequence
FHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEGMVPFVFVGTKDSIANATVLLDYHLNYLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords FMR1 protein
total genus 44
structure length 141
sequence length 141
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2qndA02
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2qndA01
1WVNA 2BA0A 2CTKA 2OPUA 2HH2A 2JEBI 4AIMA 1DTJA 1ZZIA 1ZZJA 2Z0SA 4BA1I 4WALA 2FMRA 1K1GA 4AM3A 2CTMA 4IFDG 3V69A 1J5KA 4OO1G 2JA9A 2ANRA 1WE8A 2CTFA 2PY9A 2MJHA 5C0XG 2AXYA 2CTJA 3L7ZC 1TUAA 1ZZKA 3VKEA 4B8TA 1J4WA 5K36G 2JE6I 1VIHA 2E3UA 2YQRA 1DT4A 1ZTGA 2CTEA 2HH3A 2JEAI 4LIJA 4JVHA 5JEAG 2CPQA 2QNDA 2BL5A 2CTLA 4QMFB 1EC6A 4NBQA 2ANNA 4WANA 1KHMA 3U1KA 2JZXA 2P2RA 2DGRA 2OPVA 1X4MA 4JVYA 2NN6G 2PQUA 2JVZA 1VIGA 3AEVB 4BA2I 1X4NA
chains in the Genus database with same CATH superfamily
2BA0A 2OPUA 4YY3H 2HH2A 4DV0H 1FKAH 3KDKA 3QD7X 4EC5A 2G8YA 4DUYH 2UUBH 1WHRA 4AM3A 1J5KA 2JA9A 4LF4H 4DV5H 5C0XG 2AXYA 4LF6H 1AN7A 5LMNH 2VKCA 1HNWH 4B8CD 4JI0H 2JEAI 2UUAH 2VQEH 4DR3H 4NBQA 2HHHH 4B3SH 2P2RA 2DGRA 4FJSA 1J5EH 2UU9H 4JI2H 2FPHX 3JAMW 1FJGH 3AEVB 5LMUH 1S03G 4BA2I 4PDBA 1UG8A 1X0AA 2NN6G 1PQXA 1WVNA 2CTKA 3EZJA 4NZTM 2JEBI 4AIMA 4DR1H 1DTJA 4E9JA 3J80W 4K0KH 2Z0SA 3UOEA 4BA1I 1K1GA 3J81W 2CWFA 4X66H 4JI7H 3SB1A 3FAUA 1X9ZA 3V69A 4LF9H 1XNQH 2CTFA 4NZRM 4OCHA 4X64H 1HNZH 1XRHA 1ODHA 4JI1H 4JI5H 3L7ZC 1TUAA 1VBIA 1MSZA 1ZZKA 3OTOH 1J4WA 4H8AA 1DT4A 2CTEA 2HH3A 1I94H 5BR8H 1XMQH 5DT9A 2QNDA 4G08A 4JI6H 4OX9H 4JI3H 2CTLA 4QMFB 2D9IA 4OD6A 2ANNA 1N32H 3U1KA 5LL6b 4FJUA 4B3RH 1N36H 4LFCH 4JVYA 4DR4H 1EC6A 2UXCH 1XNRH 2PT7G 4JI8H 2K1HA 1X4NA 4LFBH 4KHPH 4WANA 2X06A 4DV1H 4GKKH 4B3MH 4DV7H 1F0XA 4WALA 2LTMA 2M8WA 4LF7H 4DR5H 4JYAH 4IFDG 4NXMH 5IWAH 2VQFH 4OO1G 2ANRA 1HR0H 4X62H 2MJHA 1V9NA 4JI4H 2FFMA 1SEIA 2A1SA 3VKEA 4B8TA 3GKUA 5K36G 3RF2A 2E3UA 2YQRA 1IBKH 2LRRA 3NCVA 3GR5A 4LIJA 4DUZH 1N33H 2CPQA 4B3TH 2BL5A 1N34H 3OETA 4GKJH 1KHMA 1WTJA 2ZQEA 2CWHA 2M6QA 4YHHH 5FLXW 2O4CA 1VIGA 2CPMA 3T1YH 4NXNH 1XMOH 1S20A 1ZZJA 1ZZIA 4LFAH 4DR2H 2FMRA 2ZM6H 4DV4H 4X65H 1NXUA 5IT9W 3I0PA 2CTMA 4DV3H 3T1HH 2LF0A 2UXDH 1WE8A 2PY9A 4DR6H 5A2QW 2CTJA 4LF5H 3KDGA 1I6UA 3OSSD 2E5LH 2JE6I 1VIHA 1IBMH 4DV2H 4JV5H 2LTLA 1ZTGA 4JVHA 5JEAG 4DV6H 1Z2IA 2Y3MA 4AQYH 1HNXH 2JZXA 1V8CA 2F4VH 2OPVA 1X4MA 1IBLH 4DR7H 2PQUA 2JVZA 2UXBH 4LF8H 2UUCH 3J7AK 3GABA
chains in the Genus database with same CATH topology
1WVNA 2BA0A 2CTKA 2OPUA 2HH2A 2JEBI 4AIMA 1DTJA 1ZZIA 1ZZJA 2Z0SA 4BA1I 4WALA 2FMRA 1K1GA 4AM3A 2CTMA 4IFDG 3V69A 1J5KA 4OO1G 2JA9A 2ANRA 1WE8A 2CTFA 2PY9A 2MJHA 5C0XG 2AXYA 2CTJA 3L7ZC 1TUAA 1ZZKA 3VKEA 4B8TA 1J4WA 5K36G 2JE6I 1VIHA 2E3UA 2YQRA 1DT4A 1ZTGA 2CTEA 2HH3A 2JEAI 4LIJA 4JVHA 5JEAG 2CPQA 2QNDA 2BL5A 2CTLA 4QMFB 1EC6A 4NBQA 2ANNA 4WANA 1KHMA 3U1KA 2JZXA 2P2RA 2DGRA 2OPVA 1X4MA 4JVYA 2NN6G 2PQUA 2JVZA 1VIGA 3AEVB 4BA2I 1X4NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WVN A;  2BA0 A;  2CTK A;  2OPU A;  2HH2 A;  2JEB I;  4AIM A;  1DTJ A;  1ZZI A;  1ZZJ A;  2Z0S A;  4BA1 I;  4WAL A;  2FMR A;  1K1G A;  4AM3 A;  2CTM A;  4IFD G;  3V69 A;  1J5K A;  4OO1 G;  2JA9 A;  2ANR A;  1WE8 A;  2CTF A;  2PY9 A;  2MJH A;  5C0X G;  2AXY A;  2CTJ A;  3L7Z C;  1TUA A;  1ZZK A;  3VKE A;  4B8T A;  1J4W A;  5K36 G;  2JE6 I;  1VIH A;  2E3U A;  2YQR A;  1DT4 A;  1ZTG A;  2CTE A;  2HH3 A;  2JEA I;  4LIJ A;  4JVH A;  5JEA G;  2CPQ A;  2QND A;  2BL5 A;  2CTL A;  4QMF B;  1EC6 A;  4NBQ A;  2ANN A;  4WAN A;  1KHM A;  3U1K A;  2JZX A;  2P2R A;  2DGR A;  2OPV A;  1X4M A;  4JVY A;  2NN6 G;  2PQU A;  2JVZ A;  1VIG A;  3AEV B;  4BA2 I;  1X4N A; 
#chains in the Genus database with same CATH topology
 2BA0 A;  2OPU A;  4YY3 H;  2HH2 A;  4DV0 H;  1FKA H;  3KDK A;  3QD7 X;  4EC5 A;  2G8Y A;  4DUY H;  2UUB H;  1WHR A;  4AM3 A;  1J5K A;  2JA9 A;  4LF4 H;  4DV5 H;  5C0X G;  2AXY A;  4LF6 H;  1AN7 A;  5LMN H;  2VKC A;  1HNW H;  4B8C D;  4JI0 H;  2JEA I;  2UUA H;  2VQE H;  4DR3 H;  4NBQ A;  2HHH H;  4B3S H;  2P2R A;  2DGR A;  4FJS A;  1J5E H;  2UU9 H;  4JI2 H;  2FPH X;  3JAM W;  1FJG H;  3AEV B;  5LMU H;  1S03 G;  4BA2 I;  4PDB A;  1UG8 A;  1X0A A;  2NN6 G;  1PQX A;  1WVN A;  2CTK A;  3EZJ A;  4NZT M;  2JEB I;  4AIM A;  4DR1 H;  1DTJ A;  4E9J A;  3J80 W;  4K0K H;  2Z0S A;  3UOE A;  4BA1 I;  1K1G A;  3J81 W;  2CWF A;  4X66 H;  4JI7 H;  3SB1 A;  3FAU A;  1X9Z A;  3V69 A;  4LF9 H;  1XNQ H;  2CTF A;  4NZR M;  4OCH A;  4X64 H;  1HNZ H;  1XRH A;  1ODH A;  4JI1 H;  4JI5 H;  3L7Z C;  1TUA A;  1VBI A;  1MSZ A;  1ZZK A;  3OTO H;  1J4W A;  4H8A A;  1DT4 A;  2CTE A;  2HH3 A;  1I94 H;  5BR8 H;  1XMQ H;  5DT9 A;  2QND A;  4G08 A;  4JI6 H;  4OX9 H;  4JI3 H;  2CTL A;  4QMF B;  2D9I A;  4OD6 A;  2ANN A;  1N32 H;  3U1K A;  5LL6 b;  4FJU A;  4B3R H;  1N36 H;  4LFC H;  4JVY A;  4DR4 H;  1EC6 A;  2UXC H;  1XNR H;  2PT7 G;  4JI8 H;  2K1H A;  1X4N A;  4LFB H;  4KHP H;  4WAN A;  2X06 A;  4DV1 H;  4GKK H;  4B3M H;  4DV7 H;  1F0X A;  4WAL A;  2LTM A;  2M8W A;  4LF7 H;  4DR5 H;  4JYA H;  4IFD G;  4NXM H;  5IWA H;  2VQF H;  4OO1 G;  2ANR A;  1HR0 H;  4X62 H;  2MJH A;  1V9N A;  4JI4 H;  2FFM A;  1SEI A;  2A1S A;  3VKE A;  4B8T A;  3GKU A;  5K36 G;  3RF2 A;  2E3U A;  2YQR A;  1IBK H;  2LRR A;  3NCV A;  3GR5 A;  4LIJ A;  4DUZ H;  1N33 H;  2CPQ A;  4B3T H;  2BL5 A;  1N34 H;  3OET A;  4GKJ H;  1KHM A;  1WTJ A;  2ZQE A;  2CWH A;  2M6Q A;  4YHH H;  5FLX W;  2O4C A;  1VIG A;  2CPM A;  3T1Y H;  4NXN H;  1XMO H;  1S20 A;  1ZZJ A;  1ZZI A;  4LFA H;  4DR2 H;  2FMR A;  2ZM6 H;  4DV4 H;  4X65 H;  1NXU A;  5IT9 W;  3I0P A;  2CTM A;  4DV3 H;  3T1H H;  2LF0 A;  2UXD H;  1WE8 A;  2PY9 A;  4DR6 H;  5A2Q W;  2CTJ A;  4LF5 H;  3KDG A;  1I6U A;  3OSS D;  2E5L H;  2JE6 I;  1VIH A;  1IBM H;  4DV2 H;  4JV5 H;  2LTL A;  1ZTG A;  4JVH A;  5JEA G;  4DV6 H;  1Z2I A;  2Y3M A;  4AQY H;  1HNX H;  2JZX A;  1V8C A;  2F4V H;  2OPV A;  1X4M A;  1IBL H;  4DR7 H;  2PQU A;  2JVZ A;  2UXB H;  4LF8 H;  2UUC H;  3J7A K;  3GAB A; 
#chains in the Genus database with same CATH homology
 1WVN A;  2BA0 A;  2CTK A;  2OPU A;  2HH2 A;  2JEB I;  4AIM A;  1DTJ A;  1ZZI A;  1ZZJ A;  2Z0S A;  4BA1 I;  4WAL A;  2FMR A;  1K1G A;  4AM3 A;  2CTM A;  4IFD G;  3V69 A;  1J5K A;  4OO1 G;  2JA9 A;  2ANR A;  1WE8 A;  2CTF A;  2PY9 A;  2MJH A;  5C0X G;  2AXY A;  2CTJ A;  3L7Z C;  1TUA A;  1ZZK A;  3VKE A;  4B8T A;  1J4W A;  5K36 G;  2JE6 I;  1VIH A;  2E3U A;  2YQR A;  1DT4 A;  1ZTG A;  2CTE A;  2HH3 A;  2JEA I;  4LIJ A;  4JVH A;  5JEA G;  2CPQ A;  2QND A;  2BL5 A;  2CTL A;  4QMF B;  1EC6 A;  4NBQ A;  2ANN A;  4WAN A;  1KHM A;  3U1K A;  2JZX A;  2P2R A;  2DGR A;  2OPV A;  1X4M A;  4JVY A;  2NN6 G;  2PQU A;  2JVZ A;  1VIG A;  3AEV B;  4BA2 I;  1X4N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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