2X06A

Sulfolactate dehydrogenase from methanocaldococcus jannaschii
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
344
structure length
344
Chain Sequence
MILKPENEKKLIIDVLKKFGVPEEDAKITADVFVDADLKGFTSHGIGRFPQYITALKLGNINPKPDIKIVKESPATAVIDGDLGLGQVVGKKAMELAIKKAKNVGVGVVATRNANHFGIAGYYSELAMNQDMIGITITNTEPAMAPFGGKEKILGTNPIAIAFKGNKYKFSLDMATASIARGKILEALRKKIKIPEGCAVDKDGKPTTDPAKALEGCILPFGGPKGYGLALAIEMLSAIGGAEVGTKVKGTANPEERCTKGDLFIAINPEFFMGKEEFKRKVDELLDEIKNSEPAEGFEILIPGEIEERNKMKRKDGFEIDKNLYNQLKEICNELGLNIEDYIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Methanoarchaeal Sulfolactate Dehydrogenase: Prototype of a New Family of Nadh-Dependent Enzymes.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Methanocaldococcus jannaschii
molecule keywords L-SULFOLACTATE DEHYDROGENASE
total genus 104
structure length 344
sequence length 344
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.1.1.337: L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
pdb deposition date 2009-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 2x06A01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 2x06A02
2X06A 1V9NA 1NXUA 2CWHA 3I0PA 4FJSA 1Z2IA 4FJUA 2G8YA 1X0AA 1S20A 2CWFA 4H8AA 3UOEA 1VBIA 1WTJA 1XRHA
chains in the Genus database with same CATH superfamily
2FMRA 1S03G 4JYAH 2JVZA 1DTJA 2NN6G 2CTLA 2OPUA 4JI4H 3U1KA 2UXCH 5A2QW 2D9IA 2ZM6H 4DV5H 4JV5H 2HH3A 4DV6H 3T1YH 1HNWH 4DV1H 4LFCH 4JI0H 1UG8A 4DUYH 1XMOH 1WTJA 2CTKA 2JE6I 2CTFA 2E5LH 2MJHA 1N34H 2CTJA 1SEIA 1EC6A 4X65H 2UXDH 4OO1G 4JI6H 3J81W 1KHMA 4G08A 3JAMW 3EZJA 4NXNH 4B8TA 4B3RH 2ZQEA 2AXYA 4OD6A 2O4CA 1K1GA 5IT9W 1VBIA 4IFDG 2PQUA 1J5KA 1HNXH 2VQEH 4DR2H 4E9JA 5LMNH 4FJSA 4EC5A 2VQFH 2UUBH 4LF8H 1XNQH 1X0AA 1AN7A 2OPVA 2YQRA 4LFBH 1ZZIA 5IWAH 1ODHA 1I94H 1J5EH 2ANRA 2JA9A 4H8AA 5K36G 1FJGH 4DR6H 1WHRA 4B3TH 4GKJH 1DT4A 3AEVB 1X4MA 4JVHA 1IBMH 1ZZJA 2CTEA 2FPHX 2CPMA 4X62H 2FFMA 4LFAH 1X4NA 4YHHH 2CWFA 4LF6H 2UXBH 3KDGA 1MSZA 2CTMA 3GKUA 2DGRA 2E3UA 1N33H 5DT9A 5FLXW 3J80W 2LTMA 4DV4H 2JEAI 4LF7H 4JI2H 1ZZKA 5LL6b 3J7AK 1PQXA 4K0KH 1WE8A 3I0PA 4JI1H 1F0XA 4DV2H 4AQYH 4LF4H 2P2RA 3RF2A 2Y3MA 1WVNA 1FKAH 2M6QA 3L7ZC 1ZTGA 1HNZH 2X06A 2A1SA 2LF0A 4NBQA 4JI8H 4OX9H 4AM3A 4BA1I 2K1HA 5JEAG 2LRRA 3V69A 5LMUH 4JVYA 4B3SH 4DR4H 4YY3H 2UU9H 1J4WA 1IBLH 2UUCH 4BA2I 2CWHA 1TUAA 4LIJA 3UOEA 4LF9H 2BL5A 4X66H 1NXUA 4FJUA 4NXMH 4DR1H 4DV0H 1XMQH 2CPQA 3OETA 3SB1A 1VIGA 2PT7G 4LF5H 1N32H 2VKCA 4X64H 2JEBI 5BR8H 1XRHA 2HH2A 1Z2IA 1V8CA 4DV7H 3GABA 4DR3H 2F4VH 4JI3H 4GKKH 4JI7H 3OTOH 4WALA 2LTLA 3QD7X 4DR5H 1I6UA 5C0XG 4DR7H 4B3MH 2PY9A 2ANNA 4NZTM 4JI5H 2UUAH 2M8WA 3FAUA 3VKEA 2QNDA 1V9NA 1XNRH 4QMFB 1X9ZA 4DUZH 3T1HH 4KHPH 4WANA 4AIMA 1S20A 4NZRM 4OCHA 1HR0H 2JZXA 1N36H 1VIHA 2HHHH 2G8YA 2Z0SA 4DV3H 2BA0A 3NCVA 4B8CD 3KDKA 3GR5A 1IBKH 4PDBA 3OSSD
chains in the Genus database with same CATH topology
2X06A 1V9NA 1NXUA 2CWHA 3I0PA 4FJSA 1Z2IA 4FJUA 2G8YA 1X0AA 1S20A 2CWFA 4H8AA 3UOEA 1VBIA 1WTJA 1XRHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X06 A;  1V9N A;  1NXU A;  2CWH A;  3I0P A;  4FJS A;  1Z2I A;  4FJU A;  2G8Y A;  1X0A A;  1S20 A;  2CWF A;  4H8A A;  3UOE A;  1VBI A;  1WTJ A;  1XRH A; 
#chains in the Genus database with same CATH topology
 2FMR A;  1S03 G;  4JYA H;  2JVZ A;  1DTJ A;  2NN6 G;  2CTL A;  2OPU A;  4JI4 H;  3U1K A;  2UXC H;  5A2Q W;  2D9I A;  2ZM6 H;  4DV5 H;  4JV5 H;  2HH3 A;  4DV6 H;  3T1Y H;  1HNW H;  4DV1 H;  4LFC H;  4JI0 H;  1UG8 A;  4DUY H;  1XMO H;  1WTJ A;  2CTK A;  2JE6 I;  2CTF A;  2E5L H;  2MJH A;  1N34 H;  2CTJ A;  1SEI A;  1EC6 A;  4X65 H;  2UXD H;  4OO1 G;  4JI6 H;  3J81 W;  1KHM A;  4G08 A;  3JAM W;  3EZJ A;  4NXN H;  4B8T A;  4B3R H;  2ZQE A;  2AXY A;  4OD6 A;  2O4C A;  1K1G A;  5IT9 W;  1VBI A;  4IFD G;  2PQU A;  1J5K A;  1HNX H;  2VQE H;  4DR2 H;  4E9J A;  5LMN H;  4FJS A;  4EC5 A;  2VQF H;  2UUB H;  4LF8 H;  1XNQ H;  1X0A A;  1AN7 A;  2OPV A;  2YQR A;  4LFB H;  1ZZI A;  5IWA H;  1ODH A;  1I94 H;  1J5E H;  2ANR A;  2JA9 A;  4H8A A;  5K36 G;  1FJG H;  4DR6 H;  1WHR A;  4B3T H;  4GKJ H;  1DT4 A;  3AEV B;  1X4M A;  4JVH A;  1IBM H;  1ZZJ A;  2CTE A;  2FPH X;  2CPM A;  4X62 H;  2FFM A;  4LFA H;  1X4N A;  4YHH H;  2CWF A;  4LF6 H;  2UXB H;  3KDG A;  1MSZ A;  2CTM A;  3GKU A;  2DGR A;  2E3U A;  1N33 H;  5DT9 A;  5FLX W;  3J80 W;  2LTM A;  4DV4 H;  2JEA I;  4LF7 H;  4JI2 H;  1ZZK A;  5LL6 b;  3J7A K;  1PQX A;  4K0K H;  1WE8 A;  3I0P A;  4JI1 H;  1F0X A;  4DV2 H;  4AQY H;  4LF4 H;  2P2R A;  3RF2 A;  2Y3M A;  1WVN A;  1FKA H;  2M6Q A;  3L7Z C;  1ZTG A;  1HNZ H;  2X06 A;  2A1S A;  2LF0 A;  4NBQ A;  4JI8 H;  4OX9 H;  4AM3 A;  4BA1 I;  2K1H A;  5JEA G;  2LRR A;  3V69 A;  5LMU H;  4JVY A;  4B3S H;  4DR4 H;  4YY3 H;  2UU9 H;  1J4W A;  1IBL H;  2UUC H;  4BA2 I;  2CWH A;  1TUA A;  4LIJ A;  3UOE A;  4LF9 H;  2BL5 A;  4X66 H;  1NXU A;  4FJU A;  4NXM H;  4DR1 H;  4DV0 H;  1XMQ H;  2CPQ A;  3OET A;  3SB1 A;  1VIG A;  2PT7 G;  4LF5 H;  1N32 H;  2VKC A;  4X64 H;  2JEB I;  5BR8 H;  1XRH A;  2HH2 A;  1Z2I A;  1V8C A;  4DV7 H;  3GAB A;  4DR3 H;  2F4V H;  4JI3 H;  4GKK H;  4JI7 H;  3OTO H;  4WAL A;  2LTL A;  3QD7 X;  4DR5 H;  1I6U A;  5C0X G;  4DR7 H;  4B3M H;  2PY9 A;  2ANN A;  4NZT M;  4JI5 H;  2UUA H;  2M8W A;  3FAU A;  3VKE A;  2QND A;  1V9N A;  1XNR H;  4QMF B;  1X9Z A;  4DUZ H;  3T1H H;  4KHP H;  4WAN A;  4AIM A;  1S20 A;  4NZR M;  4OCH A;  1HR0 H;  2JZX A;  1N36 H;  1VIH A;  2HHH H;  2G8Y A;  2Z0S A;  4DV3 H;  2BA0 A;  3NCV A;  4B8C D;  3KDK A;  3GR5 A;  1IBK H;  4PDB A;  3OSS D; 
#chains in the Genus database with same CATH homology
 2X06 A;  1V9N A;  1NXU A;  2CWH A;  3I0P A;  4FJS A;  1Z2I A;  4FJU A;  2G8Y A;  1X0A A;  1S20 A;  2CWF A;  4H8A A;  3UOE A;  1VBI A;  1WTJ A;  1XRH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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