2X06A

Sulfolactate dehydrogenase from methanocaldococcus jannaschii
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
344
structure length
344
Chain Sequence
MILKPENEKKLIIDVLKKFGVPEEDAKITADVFVDADLKGFTSHGIGRFPQYITALKLGNINPKPDIKIVKESPATAVIDGDLGLGQVVGKKAMELAIKKAKNVGVGVVATRNANHFGIAGYYSELAMNQDMIGITITNTEPAMAPFGGKEKILGTNPIAIAFKGNKYKFSLDMATASIARGKILEALRKKIKIPEGCAVDKDGKPTTDPAKALEGCILPFGGPKGYGLALAIEMLSAIGGAEVGTKVKGTANPEERCTKGDLFIAINPEFFMGKEEFKRKVDELLDEIKNSEPAEGFEILIPGEIEERNKMKRKDGFEIDKNLYNQLKEICNELGLNIEDYIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Methanoarchaeal Sulfolactate Dehydrogenase: Prototype of a New Family of Nadh-Dependent Enzymes.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Methanocaldococcus jannaschii
molecule keywords L-SULFOLACTATE DEHYDROGENASE
total genus 104
structure length 344
sequence length 344
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.1.1.337: L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
pdb deposition date 2009-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 2x06A01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 2x06A02
1X0AA 4FJSA 4FJUA 2CWFA 1Z2IA 1S20A 1V9NA 2X06A 3I0PA 4H8AA 1VBIA 3UOEA 1NXUA 1WTJA 1XRHA 2G8YA 2CWHA
chains in the Genus database with same CATH superfamily
4DV7H 2MJHA 1DT4A 4BA2I 4JI7H 1V9NA 4JYAH 3AEVB 1HNXH 2ZQEA 1X9ZA 2VKCA 1VIGA 2UU9H 1XNRH 1ZZJA 2CTLA 1WE8A 1VBIA 1N36H 4OCHA 1WTJA 1S03G 2HH2A 4JI1H 1XNQH 3T1YH 4LF5H 1XMOH 2X06A 2CTFA 3KDKA 4JV5H 2JZXA 1ODHA 3J7AK 3V69A 4JI0H 2LTMA 4X64H 4DR4H 4WALA 1I6UA 1VIHA 2LF0A 4AM3A 1XMQH 1N32H 3U1KA 4OX9H 1FJGH 5FLXW 2CTMA 4NZRM 4DV2H 2AXYA 1J4WA 2UUBH 4NXMH 4K0KH 4YY3H 4OO1G 5DT9A 2LRRA 2Y3MA 4EC5A 2ANNA 1S20A 1I94H 3OSSD 4AIMA 4B8CD 4DV0H 2ANRA 3FAUA 2HHHH 2JEBI 4JVHA 2M6QA 2FPHX 1IBKH 4NZTM 4LF8H 2CWFA 3RF2A 2O4CA 4JI8H 2CTKA 3NCVA 4X62H 2A1SA 2OPUA 2BA0A 4X66H 1HR0H 3L7ZC 2UXCH 3J80W 1NXUA 4JVYA 1HNZH 1X0AA 1SEIA 1X4NA 4DR5H 2ZM6H 1AN7A 2UXDH 3OETA 4B3SH 4GKJH 1FKAH 4LIJA 4LFAH 4WANA 2UUCH 1K1GA 4JI6H 4NBQA 1J5KA 2FFMA 4NXNH 4QMFB 3OTOH 4LF6H 3EZJA 2CPMA 3SB1A 2HH3A 4DR1H 1ZZIA 1XRHA 1PQXA 4YHHH 4B3TH 2PQUA 3QD7X 2F4VH 4GKKH 4E9JA 3VKEA 1DTJA 2BL5A 2YQRA 5BR8H 1J5EH 4DR3H 1IBLH 4DV3H 2G8YA 2K1HA 2QNDA 4KHPH 4FJSA 4DV5H 1TUAA 2VQFH 1IBMH 1WVNA 2CPQA 5IT9W 1N34H 2E5LH 2LTLA 3JAMW 4LFBH 4JI3H 4B8TA 2UUAH 4B3RH 2JA9A 4B3MH 1EC6A 4DUYH 4FJUA 4LF4H 5LMNH 5A2QW 4H8AA 2PT7G 4X65H 2CTJA 2E3UA 3GABA 2D9IA 5C0XG 4DV4H 2P2RA 1HNWH 2FMRA 1N33H 4IFDG 1ZZKA 4G08A 4DV6H 4JI4H 4DR2H 2DGRA 1WHRA 3KDGA 3GR5A 2JEAI 1F0XA 2UXBH 4AQYH 4DR7H 2VQEH 5LMUH 4PDBA 5IWAH 4DUZH 5JEAG 3GKUA 3I0PA 2CTEA 4OD6A 4BA1I 4JI2H 3T1HH 4LF9H 5K36G 2Z0SA 5LL6b 2NN6G 3J81W 2CWHA 1V8CA 1ZTGA 4DV1H 1KHMA 4LFCH 1Z2IA 2JVZA 4DR6H 2M8WA 2JE6I 1UG8A 2PY9A 3UOEA 4LF7H 1MSZA 1X4MA 4JI5H 2OPVA
chains in the Genus database with same CATH topology
1X0AA 4FJSA 4FJUA 2CWFA 1Z2IA 1S20A 1V9NA 2X06A 3I0PA 4H8AA 1VBIA 3UOEA 1NXUA 1WTJA 1XRHA 2G8YA 2CWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X0A A;  4FJS A;  4FJU A;  2CWF A;  1Z2I A;  1S20 A;  1V9N A;  2X06 A;  3I0P A;  4H8A A;  1VBI A;  3UOE A;  1NXU A;  1WTJ A;  1XRH A;  2G8Y A;  2CWH A; 
#chains in the Genus database with same CATH topology
 4DV7 H;  2MJH A;  1DT4 A;  4BA2 I;  4JI7 H;  1V9N A;  4JYA H;  3AEV B;  1HNX H;  2ZQE A;  1X9Z A;  2VKC A;  1VIG A;  2UU9 H;  1XNR H;  1ZZJ A;  2CTL A;  1WE8 A;  1VBI A;  1N36 H;  4OCH A;  1WTJ A;  1S03 G;  2HH2 A;  4JI1 H;  1XNQ H;  3T1Y H;  4LF5 H;  1XMO H;  2X06 A;  2CTF A;  3KDK A;  4JV5 H;  2JZX A;  1ODH A;  3J7A K;  3V69 A;  4JI0 H;  2LTM A;  4X64 H;  4DR4 H;  4WAL A;  1I6U A;  1VIH A;  2LF0 A;  4AM3 A;  1XMQ H;  1N32 H;  3U1K A;  4OX9 H;  1FJG H;  5FLX W;  2CTM A;  4NZR M;  4DV2 H;  2AXY A;  1J4W A;  2UUB H;  4NXM H;  4K0K H;  4YY3 H;  4OO1 G;  5DT9 A;  2LRR A;  2Y3M A;  4EC5 A;  2ANN A;  1S20 A;  1I94 H;  3OSS D;  4AIM A;  4B8C D;  4DV0 H;  2ANR A;  3FAU A;  2HHH H;  2JEB I;  4JVH A;  2M6Q A;  2FPH X;  1IBK H;  4NZT M;  4LF8 H;  2CWF A;  3RF2 A;  2O4C A;  4JI8 H;  2CTK A;  3NCV A;  4X62 H;  2A1S A;  2OPU A;  2BA0 A;  4X66 H;  1HR0 H;  3L7Z C;  2UXC H;  3J80 W;  1NXU A;  4JVY A;  1HNZ H;  1X0A A;  1SEI A;  1X4N A;  4DR5 H;  2ZM6 H;  1AN7 A;  2UXD H;  3OET A;  4B3S H;  4GKJ H;  1FKA H;  4LIJ A;  4LFA H;  4WAN A;  2UUC H;  1K1G A;  4JI6 H;  4NBQ A;  1J5K A;  2FFM A;  4NXN H;  4QMF B;  3OTO H;  4LF6 H;  3EZJ A;  2CPM A;  3SB1 A;  2HH3 A;  4DR1 H;  1ZZI A;  1XRH A;  1PQX A;  4YHH H;  4B3T H;  2PQU A;  3QD7 X;  2F4V H;  4GKK H;  4E9J A;  3VKE A;  1DTJ A;  2BL5 A;  2YQR A;  5BR8 H;  1J5E H;  4DR3 H;  1IBL H;  4DV3 H;  2G8Y A;  2K1H A;  2QND A;  4KHP H;  4FJS A;  4DV5 H;  1TUA A;  2VQF H;  1IBM H;  1WVN A;  2CPQ A;  5IT9 W;  1N34 H;  2E5L H;  2LTL A;  3JAM W;  4LFB H;  4JI3 H;  4B8T A;  2UUA H;  4B3R H;  2JA9 A;  4B3M H;  1EC6 A;  4DUY H;  4FJU A;  4LF4 H;  5LMN H;  5A2Q W;  4H8A A;  2PT7 G;  4X65 H;  2CTJ A;  2E3U A;  3GAB A;  2D9I A;  5C0X G;  4DV4 H;  2P2R A;  1HNW H;  2FMR A;  1N33 H;  4IFD G;  1ZZK A;  4G08 A;  4DV6 H;  4JI4 H;  4DR2 H;  2DGR A;  1WHR A;  3KDG A;  3GR5 A;  2JEA I;  1F0X A;  2UXB H;  4AQY H;  4DR7 H;  2VQE H;  5LMU H;  4PDB A;  5IWA H;  4DUZ H;  5JEA G;  3GKU A;  3I0P A;  2CTE A;  4OD6 A;  4BA1 I;  4JI2 H;  3T1H H;  4LF9 H;  5K36 G;  2Z0S A;  5LL6 b;  2NN6 G;  3J81 W;  2CWH A;  1V8C A;  1ZTG A;  4DV1 H;  1KHM A;  4LFC H;  1Z2I A;  2JVZ A;  4DR6 H;  2M8W A;  2JE6 I;  1UG8 A;  2PY9 A;  3UOE A;  4LF7 H;  1MSZ A;  1X4M A;  4JI5 H;  2OPV A; 
#chains in the Genus database with same CATH homology
 1X0A A;  4FJS A;  4FJU A;  2CWF A;  1Z2I A;  1S20 A;  1V9N A;  2X06 A;  3I0P A;  4H8A A;  1VBI A;  3UOE A;  1NXU A;  1WTJ A;  1XRH A;  2G8Y A;  2CWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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