2ANNA

Crystal structure (i) of nova-1 kh1/kh2 domain tandem with 25 nt rna hairpin
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
175
structure length
148
Chain Sequence
GSQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPPDRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQNRVVTVSGEPEQNRKAVELIIQKIQEDP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
pubmed doi rcsb
molecule tags Rna-binding protein/rna
source organism Homo sapiens
molecule keywords 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*
total genus 41
structure length 148
sequence length 175
ec nomenclature
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA01
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2annA02
2CTKA 1WE8A 4WANA 2AXYA 1DTJA 2HH2A 2ANNA 4IFDG 4JVYA 2Z0SA 5K36G 2PQUA 2OPUA 2BL5A 4AIMA 2JA9A 2DGRA 1DT4A 2CTMA 2JE6I 4AM3A 4JVHA 3VKEA 1J4WA 2CTFA 1TUAA 1ZZIA 2MJHA 2JEBI 2PY9A 4LIJA 1WVNA 3V69A 1VIGA 4WALA 1ZZJA 1X4MA 1X4NA 5C0XG 2JEAI 1ZZKA 2JZXA 4BA1I 2OPVA 4QMFB 2JVZA 4BA2I 3U1KA 5JEAG 2P2RA 3AEVB 4NBQA 2QNDA 1EC6A 2NN6G 3L7ZC 1J5KA 1VIHA 2E3UA 2FMRA 1K1GA 4OO1G 2ANRA 2CTLA 4B8TA 1ZTGA 1KHMA 2BA0A 2HH3A 2CTEA 2YQRA 2CTJA 2CPQA
chains in the Genus database with same CATH superfamily
4LF7H 4H8AA 3OETA 4LF9H 4WANA 2AXYA 1DTJA 4NXMH 5K36G 2UXCH 2Y3MA 1IBMH 4DUYH 2PQUA 1N32H 3I0PA 2JA9A 4JVHA 1DT4A 4AM3A 2M6QA 5FLXW 4DV1H 1J4WA 4DR2H 1F0XA 4B8CD 1ZZIA 1UG8A 1XMOH 4LF5H 3GR5A 2JEBI 2PY9A 4JI0H 2VQFH 4DR6H 4GKJH 2UUBH 4DV4H 1N33H 4DV0H 3QD7X 1X9ZA 3J80W 5C0XG 1ZZJA 1ZZKA 4DR4H 4BA1I 4LF8H 4LFAH 4DV7H 2FMRA 2X06A 1NXUA 5DT9A 4JI3H 2CTLA 4JI1H 1PQXA 2BA0A 4JI8H 4AQYH 2CTEA 2LF0A 2CTKA 2LRRA 1XRHA 1Z2IA 4DUZH 1HNWH 2HH2A 5LMUH 4DR5H 4GKKH 1FJGH 4IFDG 1XNRH 4JI2H 4E9JA 3T1YH 2CTMA 4PDBA 4JI5H 2G8YA 3J81W 3UOEA 4DV5H 1XNQH 2FFMA 1S03G 1HR0H 2K1HA 1N36H 1X4MA 2HHHH 2PT7G 5IT9W 2JZXA 4BA2I 2OPVA 4QMFB 1VBIA 2JVZA 4FJUA 2UXBH 1HNZH 4NBQA 3EZJA 4YY3H 1IBLH 1EC6A 5LMNH 1VIHA 1KHMA 1FKAH 2ANRA 3SB1A 4NZTM 1AN7A 1XMQH 2YQRA 3GKUA 2CTJA 2CPQA 2CPMA 4DV2H 2E5LH 2UUCH 3RF2A 5LL6b 1V8CA 1SEIA 4DV3H 1S20A 2A1SA 4OCHA 2FPHX 4G08A 2BL5A 4X62H 4B3SH 2LTLA 4AIMA 4EC5A 5IWAH 3VKEA 4DR3H 4X65H 2ZM6H 1TUAA 4NZRM 2MJHA 4JYAH 4K0KH 2O4CA 4DV6H 1WVNA 4JI4H 1VIGA 4WALA 1X4NA 4OX9H 1J5EH 3OSSD 4DR7H 3FAUA 5JEAG 3OTOH 4YHHH 1WHRA 2QNDA 2NN6G 3L7ZC 4X64H 2E3UA 2VQEH 1N34H 1J5KA 1HNXH 4OO1G 2CWFA 4B8TA 4DR1H 4B3RH 2VKCA 4JI7H 1X0AA 1WE8A 2F4VH 2M8WA 4FJSA 4JVYA 2ANNA 2Z0SA 3T1HH 2OPUA 1V9NA 2DGRA 2JE6I 4B3MH 4B3TH 4KHPH 2LTMA 2CTFA 3JAMW 5BR8H 2UUAH 4NXNH 1I6UA 3NCVA 1MSZA 1IBKH 4LF6H 4LIJA 4JV5H 3V69A 2UU9H 4X66H 1ODHA 3KDKA 2UXDH 2JEAI 3J7AK 4OD6A 3U1KA 1I94H 3KDGA 2P2RA 3AEVB 3GABA 2ZQEA 4LFCH 4LFBH 2D9IA 1K1GA 4JI6H 1ZTGA 2CWHA 4LF4H 1WTJA 2HH3A 5A2QW
chains in the Genus database with same CATH topology
2CTKA 1WE8A 4WANA 2AXYA 1DTJA 2HH2A 2ANNA 4IFDG 4JVYA 2Z0SA 5K36G 2PQUA 2OPUA 2BL5A 4AIMA 2JA9A 2DGRA 1DT4A 2CTMA 2JE6I 4AM3A 4JVHA 3VKEA 1J4WA 2CTFA 1TUAA 1ZZIA 2MJHA 2JEBI 2PY9A 4LIJA 1WVNA 3V69A 1VIGA 4WALA 1ZZJA 1X4MA 1X4NA 5C0XG 2JEAI 1ZZKA 2JZXA 4BA1I 2OPVA 4QMFB 2JVZA 4BA2I 3U1KA 5JEAG 2P2RA 3AEVB 4NBQA 2QNDA 1EC6A 2NN6G 3L7ZC 1J5KA 1VIHA 2E3UA 2FMRA 1K1GA 4OO1G 2ANRA 2CTLA 4B8TA 1ZTGA 1KHMA 2BA0A 2HH3A 2CTEA 2YQRA 2CTJA 2CPQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CTK A;  1WE8 A;  4WAN A;  2AXY A;  1DTJ A;  2HH2 A;  2ANN A;  4IFD G;  4JVY A;  2Z0S A;  5K36 G;  2PQU A;  2OPU A;  2BL5 A;  4AIM A;  2JA9 A;  2DGR A;  1DT4 A;  2CTM A;  2JE6 I;  4AM3 A;  4JVH A;  3VKE A;  1J4W A;  2CTF A;  1TUA A;  1ZZI A;  2MJH A;  2JEB I;  2PY9 A;  4LIJ A;  1WVN A;  3V69 A;  1VIG A;  4WAL A;  1ZZJ A;  1X4M A;  1X4N A;  5C0X G;  2JEA I;  1ZZK A;  2JZX A;  4BA1 I;  2OPV A;  4QMF B;  2JVZ A;  4BA2 I;  3U1K A;  5JEA G;  2P2R A;  3AEV B;  4NBQ A;  2QND A;  1EC6 A;  2NN6 G;  3L7Z C;  1J5K A;  1VIH A;  2E3U A;  2FMR A;  1K1G A;  4OO1 G;  2ANR A;  2CTL A;  4B8T A;  1ZTG A;  1KHM A;  2BA0 A;  2HH3 A;  2CTE A;  2YQR A;  2CTJ A;  2CPQ A; 
#chains in the Genus database with same CATH topology
 4LF7 H;  4H8A A;  3OET A;  4LF9 H;  4WAN A;  2AXY A;  1DTJ A;  4NXM H;  5K36 G;  2UXC H;  2Y3M A;  1IBM H;  4DUY H;  2PQU A;  1N32 H;  3I0P A;  2JA9 A;  4JVH A;  1DT4 A;  4AM3 A;  2M6Q A;  5FLX W;  4DV1 H;  1J4W A;  4DR2 H;  1F0X A;  4B8C D;  1ZZI A;  1UG8 A;  1XMO H;  4LF5 H;  3GR5 A;  2JEB I;  2PY9 A;  4JI0 H;  2VQF H;  4DR6 H;  4GKJ H;  2UUB H;  4DV4 H;  1N33 H;  4DV0 H;  3QD7 X;  1X9Z A;  3J80 W;  5C0X G;  1ZZJ A;  1ZZK A;  4DR4 H;  4BA1 I;  4LF8 H;  4LFA H;  4DV7 H;  2FMR A;  2X06 A;  1NXU A;  5DT9 A;  4JI3 H;  2CTL A;  4JI1 H;  1PQX A;  2BA0 A;  4JI8 H;  4AQY H;  2CTE A;  2LF0 A;  2CTK A;  2LRR A;  1XRH A;  1Z2I A;  4DUZ H;  1HNW H;  2HH2 A;  5LMU H;  4DR5 H;  4GKK H;  1FJG H;  4IFD G;  1XNR H;  4JI2 H;  4E9J A;  3T1Y H;  2CTM A;  4PDB A;  4JI5 H;  2G8Y A;  3J81 W;  3UOE A;  4DV5 H;  1XNQ H;  2FFM A;  1S03 G;  1HR0 H;  2K1H A;  1N36 H;  1X4M A;  2HHH H;  2PT7 G;  5IT9 W;  2JZX A;  4BA2 I;  2OPV A;  4QMF B;  1VBI A;  2JVZ A;  4FJU A;  2UXB H;  1HNZ H;  4NBQ A;  3EZJ A;  4YY3 H;  1IBL H;  1EC6 A;  5LMN H;  1VIH A;  1KHM A;  1FKA H;  2ANR A;  3SB1 A;  4NZT M;  1AN7 A;  1XMQ H;  2YQR A;  3GKU A;  2CTJ A;  2CPQ A;  2CPM A;  4DV2 H;  2E5L H;  2UUC H;  3RF2 A;  5LL6 b;  1V8C A;  1SEI A;  4DV3 H;  1S20 A;  2A1S A;  4OCH A;  2FPH X;  4G08 A;  2BL5 A;  4X62 H;  4B3S H;  2LTL A;  4AIM A;  4EC5 A;  5IWA H;  3VKE A;  4DR3 H;  4X65 H;  2ZM6 H;  1TUA A;  4NZR M;  2MJH A;  4JYA H;  4K0K H;  2O4C A;  4DV6 H;  1WVN A;  4JI4 H;  1VIG A;  4WAL A;  1X4N A;  4OX9 H;  1J5E H;  3OSS D;  4DR7 H;  3FAU A;  5JEA G;  3OTO H;  4YHH H;  1WHR A;  2QND A;  2NN6 G;  3L7Z C;  4X64 H;  2E3U A;  2VQE H;  1N34 H;  1J5K A;  1HNX H;  4OO1 G;  2CWF A;  4B8T A;  4DR1 H;  4B3R H;  2VKC A;  4JI7 H;  1X0A A;  1WE8 A;  2F4V H;  2M8W A;  4FJS A;  4JVY A;  2ANN A;  2Z0S A;  3T1H H;  2OPU A;  1V9N A;  2DGR A;  2JE6 I;  4B3M H;  4B3T H;  4KHP H;  2LTM A;  2CTF A;  3JAM W;  5BR8 H;  2UUA H;  4NXN H;  1I6U A;  3NCV A;  1MSZ A;  1IBK H;  4LF6 H;  4LIJ A;  4JV5 H;  3V69 A;  2UU9 H;  4X66 H;  1ODH A;  3KDK A;  2UXD H;  2JEA I;  3J7A K;  4OD6 A;  3U1K A;  1I94 H;  3KDG A;  2P2R A;  3AEV B;  3GAB A;  2ZQE A;  4LFC H;  4LFB H;  2D9I A;  1K1G A;  4JI6 H;  1ZTG A;  2CWH A;  4LF4 H;  1WTJ A;  2HH3 A;  5A2Q W; 
#chains in the Genus database with same CATH homology
 2CTK A;  1WE8 A;  4WAN A;  2AXY A;  1DTJ A;  2HH2 A;  2ANN A;  4IFD G;  4JVY A;  2Z0S A;  5K36 G;  2PQU A;  2OPU A;  2BL5 A;  4AIM A;  2JA9 A;  2DGR A;  1DT4 A;  2CTM A;  2JE6 I;  4AM3 A;  4JVH A;  3VKE A;  1J4W A;  2CTF A;  1TUA A;  1ZZI A;  2MJH A;  2JEB I;  2PY9 A;  4LIJ A;  1WVN A;  3V69 A;  1VIG A;  4WAL A;  1ZZJ A;  1X4M A;  1X4N A;  5C0X G;  2JEA I;  1ZZK A;  2JZX A;  4BA1 I;  2OPV A;  4QMF B;  2JVZ A;  4BA2 I;  3U1K A;  5JEA G;  2P2R A;  3AEV B;  4NBQ A;  2QND A;  1EC6 A;  2NN6 G;  3L7Z C;  1J5K A;  1VIH A;  2E3U A;  2FMR A;  1K1G A;  4OO1 G;  2ANR A;  2CTL A;  4B8T A;  1ZTG A;  1KHM A;  2BA0 A;  2HH3 A;  2CTE A;  2YQR A;  2CTJ A;  2CPQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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