2HH2A

Solution structure of the fourth kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
79
structure length
79
Chain Sequence
GEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 79
sequence length 79
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh2A00
2DGRA 2CTFA 4AIMA 4LIJA 1ZZJA 1VIHA 2Z0SA 1J4WA 1WE8A 5JEAG 2PY9A 4JVHA 2BA0A 2CTMA 1K1GA 1J5KA 1ZTGA 4WANA 1DTJA 2CTKA 2OPUA 2JEBI 1WVNA 2YQRA 1X4NA 2FMRA 2AXYA 2PQUA 2NN6G 2HH2A 1ZZIA 5C0XG 1EC6A 1DT4A 4B8TA 2CTJA 2E3UA 1TUAA 3L7ZC 1KHMA 3U1KA 1VIGA 2JZXA 2CPQA 2JEAI 2JE6I 4QMFB 4OO1G 2ANRA 2JA9A 2JVZA 2ANNA 3V69A 4IFDG 2BL5A 2P2RA 4WALA 4BA2I 3VKEA 2HH3A 2MJHA 2CTEA 5K36G 4JVYA 2OPVA 4NBQA 2CTLA 2QNDA 1ZZKA 4BA1I 3AEVB 1X4MA 4AM3A
chains in the Genus database with same CATH superfamily
3UOEA 4AIMA 4X65H 1FJGH 3QD7X 2FFMA 3KDGA 3KDKA 5JEAG 3OSSD 2CTMA 2CWHA 2Y3MA 1K1GA 2E5LH 2F4VH 2OPUA 2JEBI 2UUAH 2FMRA 4LF5H 1HNXH 1IBLH 1J5EH 4LF8H 4GKJH 4LFCH 4DR7H 4NZTM 1KHMA 2K1HA 4OCHA 3U1KA 4DV5H 1IBKH 2JEAI 5IWAH 3J7AK 4NXMH 3JAMW 2JVZA 1AN7A 2UU9H 2MJHA 4JI1H 4JVYA 5DT9A 2QNDA 1X0AA 1XMQH 1X4MA 2UXDH 4H8AA 4JYAH 1N36H 4JI0H 3T1HH 4FJSA 2A1SA 3EZJA 3GKUA 2BA0A 2PY9A 5LMNH 4FJUA 1J5KA 2LTLA 1ZTGA 2UXBH 4DR6H 4B3RH 4DV7H 2NN6G 4JI7H 5C0XG 3T1YH 1DT4A 1I94H 4DV0H 4JI3H 2G8YA 4NXNH 3FAUA 1F0XA 1VIGA 4NZRM 4DV6H 2CPQA 4DV1H 3RF2A 1V9NA 1NXUA 2X06A 1S20A 2JA9A 5LMUH 4K0KH 4BA2I 4JI4H 3J81W 1HNZH 4LFAH 2CTEA 1IBMH 2PT7G 2CTLA 3I0PA 2O4CA 4DR4H 5BR8H 4DV4H 2LTMA 4AQYH 2CTFA 4DR5H 1ZZJA 1VIHA 4JI5H 4OX9H 2UUBH 4G08A 3NCVA 4OD6A 4LF6H 4WANA 1DTJA 2CTKA 2ZQEA 2YQRA 5A2QW 2PQUA 1X4NA 4B3MH 4B3TH 4DR2H 2HH2A 1ZZIA 4JI2H 4E9JA 2UUCH 5LL6b 4X66H 4EC5A 3L7ZC 1N33H 2LF0A 2VQEH 4DUYH 2ZM6H 4B8CD 5FLXW 4QMFB 4JI8H 2UXCH 4X64H 4LF4H 2BL5A 4YY3H 4WALA 1N34H 1V8CA 2M6QA 1FKAH 2FPHX 2HH3A 1HR0H 5IT9W 2CWFA 1PQXA 2M8WA 2OPVA 1ODHA 1ZZKA 4BA1I 4DR3H 1WTJA 4LF7H 3AEVB 1VBIA 2DGRA 3OTOH 1SEIA 4LIJA 1XRHA 4B3SH 2Z0SA 4YHHH 1J4WA 4KHPH 1WE8A 2CPMA 4JVHA 1HNWH 4PDBA 4JI6H 4DV3H 2HHHH 1XNQH 1WVNA 2AXYA 2VKCA 1WHRA 3GABA 3SB1A 1EC6A 1I6UA 4B8TA 4DUZH 1XNRH 1N32H 1X9ZA 1UG8A 2CTJA 2E3UA 4JV5H 1TUAA 2VQFH 4DV2H 1XMOH 2JZXA 1S03G 2JE6I 4GKKH 1Z2IA 3GR5A 3J80W 4OO1G 2ANRA 2ANNA 3V69A 1MSZA 2P2RA 2D9IA 4IFDG 4LF9H 4X62H 3VKEA 4DR1H 2LRRA 5K36G 4NBQA 3OETA 4AM3A 4LFBH
chains in the Genus database with same CATH topology
2DGRA 2CTFA 4AIMA 4LIJA 1ZZJA 1VIHA 2Z0SA 1J4WA 1WE8A 5JEAG 2PY9A 4JVHA 2BA0A 2CTMA 1K1GA 1J5KA 1ZTGA 4WANA 1DTJA 2CTKA 2OPUA 2JEBI 1WVNA 2YQRA 1X4NA 2FMRA 2AXYA 2PQUA 2NN6G 2HH2A 1ZZIA 5C0XG 1EC6A 1DT4A 4B8TA 2CTJA 2E3UA 1TUAA 3L7ZC 1KHMA 3U1KA 1VIGA 2JZXA 2CPQA 2JEAI 2JE6I 4QMFB 4OO1G 2ANRA 2JA9A 2JVZA 2ANNA 3V69A 4IFDG 2BL5A 2P2RA 4WALA 4BA2I 3VKEA 2HH3A 2MJHA 2CTEA 5K36G 4JVYA 2OPVA 4NBQA 2CTLA 2QNDA 1ZZKA 4BA1I 3AEVB 1X4MA 4AM3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DGR A;  2CTF A;  4AIM A;  4LIJ A;  1ZZJ A;  1VIH A;  2Z0S A;  1J4W A;  1WE8 A;  5JEA G;  2PY9 A;  4JVH A;  2BA0 A;  2CTM A;  1K1G A;  1J5K A;  1ZTG A;  4WAN A;  1DTJ A;  2CTK A;  2OPU A;  2JEB I;  1WVN A;  2YQR A;  1X4N A;  2FMR A;  2AXY A;  2PQU A;  2NN6 G;  2HH2 A;  1ZZI A;  5C0X G;  1EC6 A;  1DT4 A;  4B8T A;  2CTJ A;  2E3U A;  1TUA A;  3L7Z C;  1KHM A;  3U1K A;  1VIG A;  2JZX A;  2CPQ A;  2JEA I;  2JE6 I;  4QMF B;  4OO1 G;  2ANR A;  2JA9 A;  2JVZ A;  2ANN A;  3V69 A;  4IFD G;  2BL5 A;  2P2R A;  4WAL A;  4BA2 I;  3VKE A;  2HH3 A;  2MJH A;  2CTE A;  5K36 G;  4JVY A;  2OPV A;  4NBQ A;  2CTL A;  2QND A;  1ZZK A;  4BA1 I;  3AEV B;  1X4M A;  4AM3 A; 
#chains in the Genus database with same CATH topology
 3UOE A;  4AIM A;  4X65 H;  1FJG H;  3QD7 X;  2FFM A;  3KDG A;  3KDK A;  5JEA G;  3OSS D;  2CTM A;  2CWH A;  2Y3M A;  1K1G A;  2E5L H;  2F4V H;  2OPU A;  2JEB I;  2UUA H;  2FMR A;  4LF5 H;  1HNX H;  1IBL H;  1J5E H;  4LF8 H;  4GKJ H;  4LFC H;  4DR7 H;  4NZT M;  1KHM A;  2K1H A;  4OCH A;  3U1K A;  4DV5 H;  1IBK H;  2JEA I;  5IWA H;  3J7A K;  4NXM H;  3JAM W;  2JVZ A;  1AN7 A;  2UU9 H;  2MJH A;  4JI1 H;  4JVY A;  5DT9 A;  2QND A;  1X0A A;  1XMQ H;  1X4M A;  2UXD H;  4H8A A;  4JYA H;  1N36 H;  4JI0 H;  3T1H H;  4FJS A;  2A1S A;  3EZJ A;  3GKU A;  2BA0 A;  2PY9 A;  5LMN H;  4FJU A;  1J5K A;  2LTL A;  1ZTG A;  2UXB H;  4DR6 H;  4B3R H;  4DV7 H;  2NN6 G;  4JI7 H;  5C0X G;  3T1Y H;  1DT4 A;  1I94 H;  4DV0 H;  4JI3 H;  2G8Y A;  4NXN H;  3FAU A;  1F0X A;  1VIG A;  4NZR M;  4DV6 H;  2CPQ A;  4DV1 H;  3RF2 A;  1V9N A;  1NXU A;  2X06 A;  1S20 A;  2JA9 A;  5LMU H;  4K0K H;  4BA2 I;  4JI4 H;  3J81 W;  1HNZ H;  4LFA H;  2CTE A;  1IBM H;  2PT7 G;  2CTL A;  3I0P A;  2O4C A;  4DR4 H;  5BR8 H;  4DV4 H;  2LTM A;  4AQY H;  2CTF A;  4DR5 H;  1ZZJ A;  1VIH A;  4JI5 H;  4OX9 H;  2UUB H;  4G08 A;  3NCV A;  4OD6 A;  4LF6 H;  4WAN A;  1DTJ A;  2CTK A;  2ZQE A;  2YQR A;  5A2Q W;  2PQU A;  1X4N A;  4B3M H;  4B3T H;  4DR2 H;  2HH2 A;  1ZZI A;  4JI2 H;  4E9J A;  2UUC H;  5LL6 b;  4X66 H;  4EC5 A;  3L7Z C;  1N33 H;  2LF0 A;  2VQE H;  4DUY H;  2ZM6 H;  4B8C D;  5FLX W;  4QMF B;  4JI8 H;  2UXC H;  4X64 H;  4LF4 H;  2BL5 A;  4YY3 H;  4WAL A;  1N34 H;  1V8C A;  2M6Q A;  1FKA H;  2FPH X;  2HH3 A;  1HR0 H;  5IT9 W;  2CWF A;  1PQX A;  2M8W A;  2OPV A;  1ODH A;  1ZZK A;  4BA1 I;  4DR3 H;  1WTJ A;  4LF7 H;  3AEV B;  1VBI A;  2DGR A;  3OTO H;  1SEI A;  4LIJ A;  1XRH A;  4B3S H;  2Z0S A;  4YHH H;  1J4W A;  4KHP H;  1WE8 A;  2CPM A;  4JVH A;  1HNW H;  4PDB A;  4JI6 H;  4DV3 H;  2HHH H;  1XNQ H;  1WVN A;  2AXY A;  2VKC A;  1WHR A;  3GAB A;  3SB1 A;  1EC6 A;  1I6U A;  4B8T A;  4DUZ H;  1XNR H;  1N32 H;  1X9Z A;  1UG8 A;  2CTJ A;  2E3U A;  4JV5 H;  1TUA A;  2VQF H;  4DV2 H;  1XMO H;  2JZX A;  1S03 G;  2JE6 I;  4GKK H;  1Z2I A;  3GR5 A;  3J80 W;  4OO1 G;  2ANR A;  2ANN A;  3V69 A;  1MSZ A;  2P2R A;  2D9I A;  4IFD G;  4LF9 H;  4X62 H;  3VKE A;  4DR1 H;  2LRR A;  5K36 G;  4NBQ A;  3OET A;  4AM3 A;  4LFB H; 
#chains in the Genus database with same CATH homology
 2DGR A;  2CTF A;  4AIM A;  4LIJ A;  1ZZJ A;  1VIH A;  2Z0S A;  1J4W A;  1WE8 A;  5JEA G;  2PY9 A;  4JVH A;  2BA0 A;  2CTM A;  1K1G A;  1J5K A;  1ZTG A;  4WAN A;  1DTJ A;  2CTK A;  2OPU A;  2JEB I;  1WVN A;  2YQR A;  1X4N A;  2FMR A;  2AXY A;  2PQU A;  2NN6 G;  2HH2 A;  1ZZI A;  5C0X G;  1EC6 A;  1DT4 A;  4B8T A;  2CTJ A;  2E3U A;  1TUA A;  3L7Z C;  1KHM A;  3U1K A;  1VIG A;  2JZX A;  2CPQ A;  2JEA I;  2JE6 I;  4QMF B;  4OO1 G;  2ANR A;  2JA9 A;  2JVZ A;  2ANN A;  3V69 A;  4IFD G;  2BL5 A;  2P2R A;  4WAL A;  4BA2 I;  3VKE A;  2HH3 A;  2MJH A;  2CTE A;  5K36 G;  4JVY A;  2OPV A;  4NBQ A;  2CTL A;  2QND A;  1ZZK A;  4BA1 I;  3AEV B;  1X4M A;  4AM3 A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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