2HH3A

Solution structure of the third kh domain of ksrp
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
71
structure length
71
Chain Sequence
GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords KH-type splicing regulatory protein
total genus 18
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2006-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 2hh3A00
5C0XG 2JEBI 2ANRA 2BA0A 2AXYA 2BL5A 2YQRA 2JA9A 1WVNA 2Z0SA 1TUAA 1WE8A 5K36G 1EC6A 1X4NA 1K1GA 2FMRA 2JVZA 2JEAI 2CTEA 2CTKA 3V69A 2P2RA 4OO1G 4JVHA 1ZZKA 4QMFB 4BA1I 2PQUA 2OPVA 4WANA 2NN6G 4B8TA 2HH2A 2CTJA 1ZZJA 2CTFA 3L7ZC 2OPUA 4BA2I 2E3UA 2JZXA 3VKEA 2QNDA 1J4WA 2CTMA 1ZTGA 4NBQA 3AEVB 4AM3A 1X4MA 1DT4A 2JE6I 2DGRA 4IFDG 1J5KA 2MJHA 4LIJA 4AIMA 2ANNA 3U1KA 2PY9A 2CTLA 2HH3A 4WALA 1KHMA 1DTJA 4JVYA 1VIGA 1VIHA 1ZZIA 5JEAG 2CPQA
chains in the Genus database with same CATH superfamily
4K0KH 1HNZH 2K1HA 4JI2H 3GKUA 2UXBH 2BA0A 2YQRA 3OSSD 1WVNA 2Z0SA 4JYAH 2X06A 3OTOH 2UU9H 4B3TH 4B3MH 2JEAI 1XNQH 4QMFB 1N32H 4JI1H 4FJSA 4JI6H 4DV1H 4YHHH 4OCHA 1WHRA 2G8YA 2FFMA 2OPUA 1V8CA 3I0PA 2JZXA 1J4WA 5BR8H 2E5LH 1DT4A 2LRRA 2DGRA 2PT7G 4B3RH 4LF8H 1J5EH 1KHMA 2PY9A 2CTLA 4LFBH 1DTJA 4DV2H 4DR6H 4E9JA 4JVYA 3QD7X 3KDKA 2CPQA 1HNWH 1IBKH 4EC5A 4X62H 4LF9H 4DR4H 1MSZA 4KHPH 3UOEA 4G08A 2JA9A 1IBMH 4LF5H 1TUAA 4GKKH 1WE8A 4JI8H 1I6UA 2FMRA 2JVZA 3T1HH 4DR7H 2CTEA 2CTKA 4NZRM 2HHHH 4LF6H 2OPVA 4LF4H 2UXCH 1N34H 2F4VH 1XMOH 4DR3H 4GKJH 2CTFA 3FAUA 4BA2I 4JI5H 1X9ZA 4LFAH 2CTMA 4NBQA 5FLXW 4OX9H 4AM3A 1X4MA 2JE6I 4H8AA 1Z2IA 5LMUH 4IFDG 1IBLH 1PQXA 2ANNA 4WALA 4DR1H 2UXDH 3J81W 4AQYH 1VIGA 3GABA 1FJGH 1K1GA 2CWFA 3RF2A 4JVHA 2VQEH 2FPHX 2JEBI 3T1YH 3KDGA 5DT9A 2ANRA 5IWAH 1S20A 2AXYA 4DR2H 2LTLA 5LMNH 1XNRH 1F0XA 5LL6b 5K36G 1UG8A 3J7AK 4NXMH 1XMQH 2LF0A 4DR5H 4JI3H 3V69A 2P2RA 4DV0H 4OO1G 1XRHA 1ZZKA 2CWHA 4WANA 2NN6G 4DV7H 1ODHA 2M6QA 4NZTM 4DUYH 2LTMA 1ZZJA 1X0AA 2O4CA 2CPMA 3L7ZC 4X66H 2E3UA 3VKEA 2QNDA 1I94H 3AEVB 4DV4H 2A1SA 1WTJA 4YY3H 2UUAH 3U1KA 2Y3MA 1AN7A 1S03G 1ZZIA 1SEIA 1VBIA 3J80W 5C0XG 4B3SH 2ZQEA 3JAMW 5A2QW 1FKAH 2UUCH 4JI0H 4LF7H 4PDBA 2D9IA 2M8WA 4NXNH 2BL5A 4DV3H 3OETA 4OD6A 3GR5A 1EC6A 1X4NA 1HR0H 1HNXH 2UUBH 1NXUA 1N36H 4BA1I 2PQUA 3NCVA 4DV5H 4B8TA 4DV6H 4JI7H 4JI4H 2VQFH 2HH2A 2CTJA 3EZJA 3SB1A 4JV5H 1ZTGA 4FJUA 2VKCA 1N33H 1V9NA 4DUZH 4X65H 1J5KA 2MJHA 4LIJA 4AIMA 4X64H 4LFCH 2HH3A 2ZM6H 5IT9W 4B8CD 1VIHA 5JEAG
chains in the Genus database with same CATH topology
5C0XG 2JEBI 2ANRA 2BA0A 2AXYA 2BL5A 2YQRA 2JA9A 1WVNA 2Z0SA 1TUAA 1WE8A 5K36G 1EC6A 1X4NA 1K1GA 2FMRA 2JVZA 2JEAI 2CTEA 2CTKA 3V69A 2P2RA 4OO1G 4JVHA 1ZZKA 4QMFB 4BA1I 2PQUA 2OPVA 4WANA 2NN6G 4B8TA 2HH2A 2CTJA 1ZZJA 2CTFA 3L7ZC 2OPUA 4BA2I 2E3UA 2JZXA 3VKEA 2QNDA 1J4WA 2CTMA 1ZTGA 4NBQA 3AEVB 4AM3A 1X4MA 1DT4A 2JE6I 2DGRA 4IFDG 1J5KA 2MJHA 4LIJA 4AIMA 2ANNA 3U1KA 2PY9A 2CTLA 2HH3A 4WALA 1KHMA 1DTJA 4JVYA 1VIGA 1VIHA 1ZZIA 5JEAG 2CPQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C0X G;  2JEB I;  2ANR A;  2BA0 A;  2AXY A;  2BL5 A;  2YQR A;  2JA9 A;  1WVN A;  2Z0S A;  1TUA A;  1WE8 A;  5K36 G;  1EC6 A;  1X4N A;  1K1G A;  2FMR A;  2JVZ A;  2JEA I;  2CTE A;  2CTK A;  3V69 A;  2P2R A;  4OO1 G;  4JVH A;  1ZZK A;  4QMF B;  4BA1 I;  2PQU A;  2OPV A;  4WAN A;  2NN6 G;  4B8T A;  2HH2 A;  2CTJ A;  1ZZJ A;  2CTF A;  3L7Z C;  2OPU A;  4BA2 I;  2E3U A;  2JZX A;  3VKE A;  2QND A;  1J4W A;  2CTM A;  1ZTG A;  4NBQ A;  3AEV B;  4AM3 A;  1X4M A;  1DT4 A;  2JE6 I;  2DGR A;  4IFD G;  1J5K A;  2MJH A;  4LIJ A;  4AIM A;  2ANN A;  3U1K A;  2PY9 A;  2CTL A;  2HH3 A;  4WAL A;  1KHM A;  1DTJ A;  4JVY A;  1VIG A;  1VIH A;  1ZZI A;  5JEA G;  2CPQ A; 
#chains in the Genus database with same CATH topology
 4K0K H;  1HNZ H;  2K1H A;  4JI2 H;  3GKU A;  2UXB H;  2BA0 A;  2YQR A;  3OSS D;  1WVN A;  2Z0S A;  4JYA H;  2X06 A;  3OTO H;  2UU9 H;  4B3T H;  4B3M H;  2JEA I;  1XNQ H;  4QMF B;  1N32 H;  4JI1 H;  4FJS A;  4JI6 H;  4DV1 H;  4YHH H;  4OCH A;  1WHR A;  2G8Y A;  2FFM A;  2OPU A;  1V8C A;  3I0P A;  2JZX A;  1J4W A;  5BR8 H;  2E5L H;  1DT4 A;  2LRR A;  2DGR A;  2PT7 G;  4B3R H;  4LF8 H;  1J5E H;  1KHM A;  2PY9 A;  2CTL A;  4LFB H;  1DTJ A;  4DV2 H;  4DR6 H;  4E9J A;  4JVY A;  3QD7 X;  3KDK A;  2CPQ A;  1HNW H;  1IBK H;  4EC5 A;  4X62 H;  4LF9 H;  4DR4 H;  1MSZ A;  4KHP H;  3UOE A;  4G08 A;  2JA9 A;  1IBM H;  4LF5 H;  1TUA A;  4GKK H;  1WE8 A;  4JI8 H;  1I6U A;  2FMR A;  2JVZ A;  3T1H H;  4DR7 H;  2CTE A;  2CTK A;  4NZR M;  2HHH H;  4LF6 H;  2OPV A;  4LF4 H;  2UXC H;  1N34 H;  2F4V H;  1XMO H;  4DR3 H;  4GKJ H;  2CTF A;  3FAU A;  4BA2 I;  4JI5 H;  1X9Z A;  4LFA H;  2CTM A;  4NBQ A;  5FLX W;  4OX9 H;  4AM3 A;  1X4M A;  2JE6 I;  4H8A A;  1Z2I A;  5LMU H;  4IFD G;  1IBL H;  1PQX A;  2ANN A;  4WAL A;  4DR1 H;  2UXD H;  3J81 W;  4AQY H;  1VIG A;  3GAB A;  1FJG H;  1K1G A;  2CWF A;  3RF2 A;  4JVH A;  2VQE H;  2FPH X;  2JEB I;  3T1Y H;  3KDG A;  5DT9 A;  2ANR A;  5IWA H;  1S20 A;  2AXY A;  4DR2 H;  2LTL A;  5LMN H;  1XNR H;  1F0X A;  5LL6 b;  5K36 G;  1UG8 A;  3J7A K;  4NXM H;  1XMQ H;  2LF0 A;  4DR5 H;  4JI3 H;  3V69 A;  2P2R A;  4DV0 H;  4OO1 G;  1XRH A;  1ZZK A;  2CWH A;  4WAN A;  2NN6 G;  4DV7 H;  1ODH A;  2M6Q A;  4NZT M;  4DUY H;  2LTM A;  1ZZJ A;  1X0A A;  2O4C A;  2CPM A;  3L7Z C;  4X66 H;  2E3U A;  3VKE A;  2QND A;  1I94 H;  3AEV B;  4DV4 H;  2A1S A;  1WTJ A;  4YY3 H;  2UUA H;  3U1K A;  2Y3M A;  1AN7 A;  1S03 G;  1ZZI A;  1SEI A;  1VBI A;  3J80 W;  5C0X G;  4B3S H;  2ZQE A;  3JAM W;  5A2Q W;  1FKA H;  2UUC H;  4JI0 H;  4LF7 H;  4PDB A;  2D9I A;  2M8W A;  4NXN H;  2BL5 A;  4DV3 H;  3OET A;  4OD6 A;  3GR5 A;  1EC6 A;  1X4N A;  1HR0 H;  1HNX H;  2UUB H;  1NXU A;  1N36 H;  4BA1 I;  2PQU A;  3NCV A;  4DV5 H;  4B8T A;  4DV6 H;  4JI7 H;  4JI4 H;  2VQF H;  2HH2 A;  2CTJ A;  3EZJ A;  3SB1 A;  4JV5 H;  1ZTG A;  4FJU A;  2VKC A;  1N33 H;  1V9N A;  4DUZ H;  4X65 H;  1J5K A;  2MJH A;  4LIJ A;  4AIM A;  4X64 H;  4LFC H;  2HH3 A;  2ZM6 H;  5IT9 W;  4B8C D;  1VIH A;  5JEA G; 
#chains in the Genus database with same CATH homology
 5C0X G;  2JEB I;  2ANR A;  2BA0 A;  2AXY A;  2BL5 A;  2YQR A;  2JA9 A;  1WVN A;  2Z0S A;  1TUA A;  1WE8 A;  5K36 G;  1EC6 A;  1X4N A;  1K1G A;  2FMR A;  2JVZ A;  2JEA I;  2CTE A;  2CTK A;  3V69 A;  2P2R A;  4OO1 G;  4JVH A;  1ZZK A;  4QMF B;  4BA1 I;  2PQU A;  2OPV A;  4WAN A;  2NN6 G;  4B8T A;  2HH2 A;  2CTJ A;  1ZZJ A;  2CTF A;  3L7Z C;  2OPU A;  4BA2 I;  2E3U A;  2JZX A;  3VKE A;  2QND A;  1J4W A;  2CTM A;  1ZTG A;  4NBQ A;  3AEV B;  4AM3 A;  1X4M A;  1DT4 A;  2JE6 I;  2DGR A;  4IFD G;  1J5K A;  2MJH A;  4LIJ A;  4AIM A;  2ANN A;  3U1K A;  2PY9 A;  2CTL A;  2HH3 A;  4WAL A;  1KHM A;  1DTJ A;  4JVY A;  1VIG A;  1VIH A;  1ZZI A;  5JEA G;  2CPQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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