2LRRA

Solution structure of the r3h domain from human smubp-2 in complex with 2'-deoxyguanosine-5'-monophosphate
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
70
structure length
70
Chain Sequence
PEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for 5'-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Smubp-2
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DNA-binding protein SMUBP-2
total genus 20
structure length 70
sequence length 70
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2012-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01424 R3H R3H domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.50 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 R3H-like domain 2lrrA00
2CPMA 2LRRA 1MSZA 1WHRA 3GKUA 1UG8A 2A1SA
chains in the Genus database with same CATH superfamily
4PDBA 4LFAH 3U1KA 5LL6b 1MSZA 2HH3A 4NZTM 2CWHA 2JVZA 2UUAH 2UXDH 4X66H 1NXUA 2LF0A 1HNWH 1PQXA 2BA0A 3OTOH 4DV7H 4NXNH 2M8WA 1I94H 4OCHA 4QMFB 2HH2A 2ANRA 4EC5A 4B8TA 4B3RH 5BR8H 4DV4H 2OPVA 3V69A 5FLXW 2PQUA 2UUBH 4JI5H 1K1GA 1X9ZA 1DTJA 4BA1I 2F4VH 2ZM6H 1UG8A 2HHHH 1SEIA 3EZJA 4H8AA 4AIMA 1HNZH 4LF4H 2LTLA 2CTKA 1ZTGA 2ANNA 2E5LH 4IFDG 4LF8H 4AM3A 2O4CA 4LFBH 1WHRA 1X4MA 4DR3H 4JI1H 2CTJA 3L7ZC 4B3MH 1DT4A 2VQFH 4LF5H 5LMUH 1J5EH 4YY3H 1J5KA 2JEAI 1I6UA 2FPHX 2X06A 4JVHA 1XRHA 4JI4H 1IBLH 4K0KH 2Z0SA 2P2RA 3NCVA 2UXBH 4NZRM 4LF7H 1N33H 2JEBI 2G8YA 2JE6I 3GR5A 2CPQA 4DV0H 2UUCH 4LFCH 2LTMA 5C0XG 4G08A 4X64H 2AXYA 1S03G 4NBQA 4YHHH 1F0XA 2CWFA 3T1YH 1N32H 1S20A 2A1SA 4DR7H 4DV3H 2UU9H 2M6QA 4JI0H 2JZXA 4DV1H 4KHPH 4DR1H 1XNRH 2PY9A 4FJSA 1X0AA 5A2QW 4BA2I 3KDKA 1HR0H 4AQYH 1HNXH 3J81W 2NN6G 4DR2H 3UOEA 1XNQH 2ZQEA 2CTFA 2Y3MA 1Z2IA 4JI8H 3OETA 1EC6A 4E9JA 2LRRA 4LIJA 3RF2A 2YQRA 3T1HH 4DV6H 1ZZJA 1IBKH 1WE8A 4DV2H 4JYAH 4B8CD 3AEVB 1N36H 1V9NA 4OX9H 4GKJH 1FKAH 3VKEA 4LF9H 4DR4H 2BL5A 2CPMA 2D9IA 2PT7G 3JAMW 4B3TH 1WTJA 4WANA 4DUZH 3J80W 1AN7A 1TUAA 2VQEH 4JI7H 2FFMA 4DV5H 4FJUA 1XMOH 4OD6A 1VIGA 2OPUA 2CTLA 5DT9A 1KHMA 1FJGH 4JI3H 4LF6H 2JA9A 1ZZKA 4X62H 1WVNA 1IBMH 1XMQH 2VKCA 2UXCH 2QNDA 3J7AK 4B3SH 4GKKH 1N34H 3GKUA 4JI2H 5IT9W 4JV5H 1ODHA 4JI6H 3GABA 4NXMH 2DGRA 1VBIA 1X4NA 1J4WA 3I0PA 2CTMA 3SB1A 4DUYH 3KDGA 4X65H 2CTEA 4WALA 3OSSD 2FMRA 2E3UA 2K1HA 1ZZIA 2MJHA 5LMNH 4JVYA 4DR5H 4OO1G 3FAUA 4DR6H 5IWAH 1VIHA 5K36G 3QD7X 1V8CA 5JEAG
chains in the Genus database with same CATH topology
2CPMA 2LRRA 1MSZA 1WHRA 3GKUA 1UG8A 2A1SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CPM A;  2LRR A;  1MSZ A;  1WHR A;  3GKU A;  1UG8 A;  2A1S A; 
#chains in the Genus database with same CATH topology
 4PDB A;  4LFA H;  3U1K A;  5LL6 b;  1MSZ A;  2HH3 A;  4NZT M;  2CWH A;  2JVZ A;  2UUA H;  2UXD H;  4X66 H;  1NXU A;  2LF0 A;  1HNW H;  1PQX A;  2BA0 A;  3OTO H;  4DV7 H;  4NXN H;  2M8W A;  1I94 H;  4OCH A;  4QMF B;  2HH2 A;  2ANR A;  4EC5 A;  4B8T A;  4B3R H;  5BR8 H;  4DV4 H;  2OPV A;  3V69 A;  5FLX W;  2PQU A;  2UUB H;  4JI5 H;  1K1G A;  1X9Z A;  1DTJ A;  4BA1 I;  2F4V H;  2ZM6 H;  1UG8 A;  2HHH H;  1SEI A;  3EZJ A;  4H8A A;  4AIM A;  1HNZ H;  4LF4 H;  2LTL A;  2CTK A;  1ZTG A;  2ANN A;  2E5L H;  4IFD G;  4LF8 H;  4AM3 A;  2O4C A;  4LFB H;  1WHR A;  1X4M A;  4DR3 H;  4JI1 H;  2CTJ A;  3L7Z C;  4B3M H;  1DT4 A;  2VQF H;  4LF5 H;  5LMU H;  1J5E H;  4YY3 H;  1J5K A;  2JEA I;  1I6U A;  2FPH X;  2X06 A;  4JVH A;  1XRH A;  4JI4 H;  1IBL H;  4K0K H;  2Z0S A;  2P2R A;  3NCV A;  2UXB H;  4NZR M;  4LF7 H;  1N33 H;  2JEB I;  2G8Y A;  2JE6 I;  3GR5 A;  2CPQ A;  4DV0 H;  2UUC H;  4LFC H;  2LTM A;  5C0X G;  4G08 A;  4X64 H;  2AXY A;  1S03 G;  4NBQ A;  4YHH H;  1F0X A;  2CWF A;  3T1Y H;  1N32 H;  1S20 A;  2A1S A;  4DR7 H;  4DV3 H;  2UU9 H;  2M6Q A;  4JI0 H;  2JZX A;  4DV1 H;  4KHP H;  4DR1 H;  1XNR H;  2PY9 A;  4FJS A;  1X0A A;  5A2Q W;  4BA2 I;  3KDK A;  1HR0 H;  4AQY H;  1HNX H;  3J81 W;  2NN6 G;  4DR2 H;  3UOE A;  1XNQ H;  2ZQE A;  2CTF A;  2Y3M A;  1Z2I A;  4JI8 H;  3OET A;  1EC6 A;  4E9J A;  2LRR A;  4LIJ A;  3RF2 A;  2YQR A;  3T1H H;  4DV6 H;  1ZZJ A;  1IBK H;  1WE8 A;  4DV2 H;  4JYA H;  4B8C D;  3AEV B;  1N36 H;  1V9N A;  4OX9 H;  4GKJ H;  1FKA H;  3VKE A;  4LF9 H;  4DR4 H;  2BL5 A;  2CPM A;  2D9I A;  2PT7 G;  3JAM W;  4B3T H;  1WTJ A;  4WAN A;  4DUZ H;  3J80 W;  1AN7 A;  1TUA A;  2VQE H;  4JI7 H;  2FFM A;  4DV5 H;  4FJU A;  1XMO H;  4OD6 A;  1VIG A;  2OPU A;  2CTL A;  5DT9 A;  1KHM A;  1FJG H;  4JI3 H;  4LF6 H;  2JA9 A;  1ZZK A;  4X62 H;  1WVN A;  1IBM H;  1XMQ H;  2VKC A;  2UXC H;  2QND A;  3J7A K;  4B3S H;  4GKK H;  1N34 H;  3GKU A;  4JI2 H;  5IT9 W;  4JV5 H;  1ODH A;  4JI6 H;  3GAB A;  4NXM H;  2DGR A;  1VBI A;  1X4N A;  1J4W A;  3I0P A;  2CTM A;  3SB1 A;  4DUY H;  3KDG A;  4X65 H;  2CTE A;  4WAL A;  3OSS D;  2FMR A;  2E3U A;  2K1H A;  1ZZI A;  2MJH A;  5LMN H;  4JVY A;  4DR5 H;  4OO1 G;  3FAU A;  4DR6 H;  5IWA H;  1VIH A;  5K36 G;  3QD7 X;  1V8C A;  5JEA G; 
#chains in the Genus database with same CATH homology
 2CPM A;  2LRR A;  1MSZ A;  1WHR A;  3GKU A;  1UG8 A;  2A1S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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