2X06A

Sulfolactate dehydrogenase from methanocaldococcus jannaschii
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
344
structure length
344
Chain Sequence
MILKPENEKKLIIDVLKKFGVPEEDAKITADVFVDADLKGFTSHGIGRFPQYITALKLGNINPKPDIKIVKESPATAVIDGDLGLGQVVGKKAMELAIKKAKNVGVGVVATRNANHFGIAGYYSELAMNQDMIGITITNTEPAMAPFGGKEKILGTNPIAIAFKGNKYKFSLDMATASIARGKILEALRKKIKIPEGCAVDKDGKPTTDPAKALEGCILPFGGPKGYGLALAIEMLSAIGGAEVGTKVKGTANPEERCTKGDLFIAINPEFFMGKEEFKRKVDELLDEIKNSEPAEGFEILIPGEIEERNKMKRKDGFEIDKNLYNQLKEICNELGLNIEDYIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Methanoarchaeal Sulfolactate Dehydrogenase: Prototype of a New Family of Nadh-Dependent Enzymes.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Methanocaldococcus jannaschii
molecule keywords L-SULFOLACTATE DEHYDROGENASE
total genus 104
structure length 344
sequence length 344
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.1.1.337: L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
pdb deposition date 2009-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 2x06A01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 2x06A02
2CWHA 3I0PA 2CWFA 1NXUA 1WTJA 1Z2IA 1VBIA 1V9NA 3UOEA 1X0AA 4H8AA 2X06A 1S20A 4FJUA 4FJSA 1XRHA 2G8YA
chains in the Genus database with same CATH superfamily
4NZTM 4LF7H 1XMQH 1J4WA 5C0XG 1EC6A 4X65H 1PQXA 2CPQA 4IFDG 2CWHA 1K1GA 2OPVA 5LMUH 2JE6I 4DV6H 3FAUA 4LFBH 1XNRH 3T1YH 2HH3A 4QMFB 1XRHA 5LMNH 2CTFA 2G8YA 5JEAG 3V69A 1F0XA 5A2QW 3SB1A 3U1KA 4LF6H 1FJGH 4JI8H 2ZQEA 4H8AA 2CTKA 4JI0H 4B3RH 3OTOH 4OO1G 4NZRM 1KHMA 3GKUA 2FPHX 1J5KA 2UUCH 1HNWH 2UUAH 1S03G 4X62H 3AEVB 1I6UA 3L7ZC 1IBLH 1N32H 5IWAH 2PQUA 2UXBH 2LTLA 2UU9H 2UUBH 2O4CA 4DV2H 3EZJA 1ODHA 4LFAH 1VIHA 2VQEH 3VKEA 2JA9A 4JI5H 3J7AK 4WANA 4OX9H 1NXUA 2CPMA 3GR5A 4B3SH 5DT9A 4AIMA 2LRRA 2OPUA 4GKKH 4FJSA 1HNXH 3GABA 4NXMH 2JEAI 1WVNA 4EC5A 4DV4H 4DV3H 1N33H 2JZXA 2LF0A 1ZTGA 4JVHA 1DT4A 4DR2H 4JI7H 4JYAH 2QNDA 2FMRA 4LF4H 4PDBA 3JAMW 1N34H 1ZZKA 2FFMA 3QD7X 5BR8H 1V8CA 2ZM6H 1IBMH 2DGRA 4LFCH 2K1HA 4GKJH 4DV5H 2ANRA 2VQFH 4B3TH 1IBKH 1WTJA 2CTJA 2PY9A 4NXNH 4FJUA 2UXDH 1SEIA 3KDGA 2BA0A 4DR1H 2VKCA 1N36H 1AN7A 1UG8A 2CTEA 4OD6A 2AXYA 2UXCH 4E9JA 3KDKA 4X64H 4B8TA 2NN6G 5IT9W 2JVZA 1XMOH 5LL6b 4YY3H 3J81W 2D9IA 2BL5A 4DR5H 2A1SA 2JEBI 4LF8H 2Y3MA 2E3UA 4DR7H 2HH2A 1MSZA 4JVYA 1J5EH 4JI2H 1Z2IA 1VBIA 4JI1H 4DR4H 4LIJA 1ZZIA 2MJHA 4JI3H 1TUAA 4OCHA 1VIGA 4KHPH 4X66H 4DR3H 3T1HH 4DUZH 1I94H 1HR0H 4DR6H 2P2RA 2CTLA 2PT7G 4G08A 2ANNA 4BA2I 2M8WA 4K0KH 3OETA 4B8CD 3OSSD 4LF9H 1ZZJA 2YQRA 2CWFA 2M6QA 1XNQH 1V9NA 2CTMA 4WALA 4DV1H 4B3MH 1X4NA 3NCVA 4JI4H 4YHHH 4JI6H 3RF2A 1X4MA 4BA1I 1HNZH 3UOEA 5K36G 4LF5H 2Z0SA 1FKAH 2F4VH 2LTMA 5FLXW 4NBQA 1WHRA 1X9ZA 3I0PA 2E5LH 4DV0H 1DTJA 3J80W 4AM3A 4JV5H 4AQYH 1X0AA 4DV7H 2X06A 1S20A 4DUYH 1WE8A 2HHHH
chains in the Genus database with same CATH topology
2CWHA 3I0PA 2CWFA 1NXUA 1WTJA 1Z2IA 1VBIA 1V9NA 3UOEA 1X0AA 4H8AA 2X06A 1S20A 4FJUA 4FJSA 1XRHA 2G8YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CWH A;  3I0P A;  2CWF A;  1NXU A;  1WTJ A;  1Z2I A;  1VBI A;  1V9N A;  3UOE A;  1X0A A;  4H8A A;  2X06 A;  1S20 A;  4FJU A;  4FJS A;  1XRH A;  2G8Y A; 
#chains in the Genus database with same CATH topology
 4NZT M;  4LF7 H;  1XMQ H;  1J4W A;  5C0X G;  1EC6 A;  4X65 H;  1PQX A;  2CPQ A;  4IFD G;  2CWH A;  1K1G A;  2OPV A;  5LMU H;  2JE6 I;  4DV6 H;  3FAU A;  4LFB H;  1XNR H;  3T1Y H;  2HH3 A;  4QMF B;  1XRH A;  5LMN H;  2CTF A;  2G8Y A;  5JEA G;  3V69 A;  1F0X A;  5A2Q W;  3SB1 A;  3U1K A;  4LF6 H;  1FJG H;  4JI8 H;  2ZQE A;  4H8A A;  2CTK A;  4JI0 H;  4B3R H;  3OTO H;  4OO1 G;  4NZR M;  1KHM A;  3GKU A;  2FPH X;  1J5K A;  2UUC H;  1HNW H;  2UUA H;  1S03 G;  4X62 H;  3AEV B;  1I6U A;  3L7Z C;  1IBL H;  1N32 H;  5IWA H;  2PQU A;  2UXB H;  2LTL A;  2UU9 H;  2UUB H;  2O4C A;  4DV2 H;  3EZJ A;  1ODH A;  4LFA H;  1VIH A;  2VQE H;  3VKE A;  2JA9 A;  4JI5 H;  3J7A K;  4WAN A;  4OX9 H;  1NXU A;  2CPM A;  3GR5 A;  4B3S H;  5DT9 A;  4AIM A;  2LRR A;  2OPU A;  4GKK H;  4FJS A;  1HNX H;  3GAB A;  4NXM H;  2JEA I;  1WVN A;  4EC5 A;  4DV4 H;  4DV3 H;  1N33 H;  2JZX A;  2LF0 A;  1ZTG A;  4JVH A;  1DT4 A;  4DR2 H;  4JI7 H;  4JYA H;  2QND A;  2FMR A;  4LF4 H;  4PDB A;  3JAM W;  1N34 H;  1ZZK A;  2FFM A;  3QD7 X;  5BR8 H;  1V8C A;  2ZM6 H;  1IBM H;  2DGR A;  4LFC H;  2K1H A;  4GKJ H;  4DV5 H;  2ANR A;  2VQF H;  4B3T H;  1IBK H;  1WTJ A;  2CTJ A;  2PY9 A;  4NXN H;  4FJU A;  2UXD H;  1SEI A;  3KDG A;  2BA0 A;  4DR1 H;  2VKC A;  1N36 H;  1AN7 A;  1UG8 A;  2CTE A;  4OD6 A;  2AXY A;  2UXC H;  4E9J A;  3KDK A;  4X64 H;  4B8T A;  2NN6 G;  5IT9 W;  2JVZ A;  1XMO H;  5LL6 b;  4YY3 H;  3J81 W;  2D9I A;  2BL5 A;  4DR5 H;  2A1S A;  2JEB I;  4LF8 H;  2Y3M A;  2E3U A;  4DR7 H;  2HH2 A;  1MSZ A;  4JVY A;  1J5E H;  4JI2 H;  1Z2I A;  1VBI A;  4JI1 H;  4DR4 H;  4LIJ A;  1ZZI A;  2MJH A;  4JI3 H;  1TUA A;  4OCH A;  1VIG A;  4KHP H;  4X66 H;  4DR3 H;  3T1H H;  4DUZ H;  1I94 H;  1HR0 H;  4DR6 H;  2P2R A;  2CTL A;  2PT7 G;  4G08 A;  2ANN A;  4BA2 I;  2M8W A;  4K0K H;  3OET A;  4B8C D;  3OSS D;  4LF9 H;  1ZZJ A;  2YQR A;  2CWF A;  2M6Q A;  1XNQ H;  1V9N A;  2CTM A;  4WAL A;  4DV1 H;  4B3M H;  1X4N A;  3NCV A;  4JI4 H;  4YHH H;  4JI6 H;  3RF2 A;  1X4M A;  4BA1 I;  1HNZ H;  3UOE A;  5K36 G;  4LF5 H;  2Z0S A;  1FKA H;  2F4V H;  2LTM A;  5FLX W;  4NBQ A;  1WHR A;  1X9Z A;  3I0P A;  2E5L H;  4DV0 H;  1DTJ A;  3J80 W;  4AM3 A;  4JV5 H;  4AQY H;  1X0A A;  4DV7 H;  2X06 A;  1S20 A;  4DUY H;  1WE8 A;  2HHH H; 
#chains in the Genus database with same CATH homology
 2CWH A;  3I0P A;  2CWF A;  1NXU A;  1WTJ A;  1Z2I A;  1VBI A;  1V9N A;  3UOE A;  1X0A A;  4H8A A;  2X06 A;  1S20 A;  4FJU A;  4FJS A;  1XRH A;  2G8Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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