3VKEA

Contribution of the first k-homology domain of poly(c)-binding protein 1 to its affinity and specificity for c-rich oligonucleotides
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
76
structure length
76
Chain Sequence
HMLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNSPERIITLTGPTNAIFKAFAMIIDKLEEDINSSW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Homo sapiens
molecule keywords Poly(rC)-binding protein 1
total genus 23
structure length 76
sequence length 76
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 3vkeA00
2JA9A 1WE8A 2JZXA 1J5KA 2PQUA 1X4NA 5C0XG 5K36G 4QMFB 3U1KA 2DGRA 1VIGA 2CTKA 1TUAA 2CTEA 1DTJA 4LIJA 2JVZA 2MJHA 2CTFA 4AM3A 4IFDG 2OPUA 4JVYA 2NN6G 4AIMA 4BA1I 2ANNA 2JEAI 5JEAG 1VIHA 2QNDA 4WANA 2CTJA 1ZTGA 2JE6I 1KHMA 4OO1G 1ZZJA 2CTMA 2BL5A 2CPQA 2Z0SA 3L7ZC 1K1GA 2JEBI 1ZZIA 1WVNA 1ZZKA 4BA2I 2PY9A 3V69A 4WALA 3VKEA 3AEVB 1EC6A 4NBQA 4JVHA 1J4WA 1DT4A 1X4MA 2CTLA 2YQRA 2P2RA 2HH3A 2AXYA 2HH2A 2OPVA 2E3UA 4B8TA 2ANRA 2FMRA 2BA0A
chains in the Genus database with same CATH superfamily
1X0AA 2VQEH 4B8CD 1J5KA 2UUCH 1X4NA 1F0XA 5C0XG 4QMFB 3U1KA 4X62H 2CWHA 2DGRA 2CTKA 4EC5A 4LIJA 1I94H 2MJHA 4JI6H 4LFBH 2CTFA 4DV6H 4JVYA 2VKCA 5A2QW 2NN6G 1WHRA 4WANA 2FPHX 4LF7H 1WTJA 2JE6I 3SB1A 1FKAH 2CTMA 2BL5A 3T1YH 2CPMA 1K1GA 2JEBI 4B3RH 1ZZKA 4BA2I 4YY3H 4OCHA 2F4VH 1EC6A 3VKEA 4DR3H 1N32H 1J4WA 3I0PA 1DT4A 2PT7G 1V9NA 4B3SH 1XNRH 2AXYA 2HHHH 2K1HA 4LF9H 2M8WA 1PQXA 2E3UA 3QD7X 5BR8H 4JI1H 3J80W 2BA0A 2CWFA 1WE8A 5IT9W 1XMOH 3GKUA 5FLXW 1N34H 4GKKH 4JI5H 3J81W 4JI8H 2M6QA 4OX9H 3OSSD 4B3TH 1HNXH 5DT9A 1TUAA 2CTEA 3FAUA 4DUYH 4PDBA 4DV5H 2OPUA 2UXDH 4AIMA 2ANNA 4KHPH 4JI2H 1VIHA 3OETA 2E5LH 2ZM6H 4OO1G 1IBMH 1NXUA 3OTOH 4JYAH 3NCVA 5LMUH 3UOEA 1HR0H 4YHHH 4DV1H 4NXNH 5IWAH 3V69A 4DUZH 3AEVB 2UUAH 2UXBH 4JVHA 2HH3A 1FJGH 4NZTM 4B8TA 2UUBH 2LTLA 2O4CA 1X9ZA 2VQFH 4DR6H 1S03G 1XMQH 5K36G 4LF4H 4E9JA 2JVZA 4IFDG 1HNZH 4OD6A 4BA1I 2UU9H 4JI7H 5JEAG 4X64H 3T1HH 4JI0H 1S20A 2CTJA 1KHMA 2ZQEA 2X06A 1ODHA 1ZZIA 1WVNA 3KDGA 2PY9A 4LFAH 4FJSA 4WALA 3KDKA 4GKJH 1N33H 1X4MA 1MSZA 2CTLA 4JI3H 3J7AK 1IBKH 1XRHA 4FJUA 3RF2A 4DR4H 4AQYH 4AM3A 4JI4H 2Y3MA 2FMRA 3EZJA 4DV4H 2JA9A 4DV7H 4DR5H 2JZXA 1J5EH 2PQUA 2G8YA 1VBIA 4NZRM 4DR7H 4DV2H 1V8CA 1VIGA 4DV0H 1DTJA 2LRRA 2A1SA 2D9IA 3GABA 4G08A 2JEAI 5LMNH 2QNDA 3GR5A 1ZTGA 2LF0A 4LFCH 1ZZJA 2Z0SA 1UG8A 2CPQA 3L7ZC 1IBLH 1N36H 4JV5H 4LF5H 4K0KH 1HNWH 1Z2IA 1SEIA 3JAMW 4NBQA 4DR1H 1I6UA 2YQRA 4X65H 2P2RA 4LF8H 4NXMH 4B3MH 4DV3H 1AN7A 2HH2A 2OPVA 5LL6b 1XNQH 4LF6H 2ANRA 2UXCH 4X66H 4DR2H 2LTMA 2FFMA 4H8AA
chains in the Genus database with same CATH topology
2JA9A 1WE8A 2JZXA 1J5KA 2PQUA 1X4NA 5C0XG 5K36G 4QMFB 3U1KA 2DGRA 1VIGA 2CTKA 1TUAA 2CTEA 1DTJA 4LIJA 2JVZA 2MJHA 2CTFA 4AM3A 4IFDG 2OPUA 4JVYA 2NN6G 4AIMA 4BA1I 2ANNA 2JEAI 5JEAG 1VIHA 2QNDA 4WANA 2CTJA 1ZTGA 2JE6I 1KHMA 4OO1G 1ZZJA 2CTMA 2BL5A 2CPQA 2Z0SA 3L7ZC 1K1GA 2JEBI 1ZZIA 1WVNA 1ZZKA 4BA2I 2PY9A 3V69A 4WALA 3VKEA 3AEVB 1EC6A 4NBQA 4JVHA 1J4WA 1DT4A 1X4MA 2CTLA 2YQRA 2P2RA 2HH3A 2AXYA 2HH2A 2OPVA 2E3UA 4B8TA 2ANRA 2FMRA 2BA0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA9 A;  1WE8 A;  2JZX A;  1J5K A;  2PQU A;  1X4N A;  5C0X G;  5K36 G;  4QMF B;  3U1K A;  2DGR A;  1VIG A;  2CTK A;  1TUA A;  2CTE A;  1DTJ A;  4LIJ A;  2JVZ A;  2MJH A;  2CTF A;  4AM3 A;  4IFD G;  2OPU A;  4JVY A;  2NN6 G;  4AIM A;  4BA1 I;  2ANN A;  2JEA I;  5JEA G;  1VIH A;  2QND A;  4WAN A;  2CTJ A;  1ZTG A;  2JE6 I;  1KHM A;  4OO1 G;  1ZZJ A;  2CTM A;  2BL5 A;  2CPQ A;  2Z0S A;  3L7Z C;  1K1G A;  2JEB I;  1ZZI A;  1WVN A;  1ZZK A;  4BA2 I;  2PY9 A;  3V69 A;  4WAL A;  3VKE A;  3AEV B;  1EC6 A;  4NBQ A;  4JVH A;  1J4W A;  1DT4 A;  1X4M A;  2CTL A;  2YQR A;  2P2R A;  2HH3 A;  2AXY A;  2HH2 A;  2OPV A;  2E3U A;  4B8T A;  2ANR A;  2FMR A;  2BA0 A; 
#chains in the Genus database with same CATH topology
 1X0A A;  2VQE H;  4B8C D;  1J5K A;  2UUC H;  1X4N A;  1F0X A;  5C0X G;  4QMF B;  3U1K A;  4X62 H;  2CWH A;  2DGR A;  2CTK A;  4EC5 A;  4LIJ A;  1I94 H;  2MJH A;  4JI6 H;  4LFB H;  2CTF A;  4DV6 H;  4JVY A;  2VKC A;  5A2Q W;  2NN6 G;  1WHR A;  4WAN A;  2FPH X;  4LF7 H;  1WTJ A;  2JE6 I;  3SB1 A;  1FKA H;  2CTM A;  2BL5 A;  3T1Y H;  2CPM A;  1K1G A;  2JEB I;  4B3R H;  1ZZK A;  4BA2 I;  4YY3 H;  4OCH A;  2F4V H;  1EC6 A;  3VKE A;  4DR3 H;  1N32 H;  1J4W A;  3I0P A;  1DT4 A;  2PT7 G;  1V9N A;  4B3S H;  1XNR H;  2AXY A;  2HHH H;  2K1H A;  4LF9 H;  2M8W A;  1PQX A;  2E3U A;  3QD7 X;  5BR8 H;  4JI1 H;  3J80 W;  2BA0 A;  2CWF A;  1WE8 A;  5IT9 W;  1XMO H;  3GKU A;  5FLX W;  1N34 H;  4GKK H;  4JI5 H;  3J81 W;  4JI8 H;  2M6Q A;  4OX9 H;  3OSS D;  4B3T H;  1HNX H;  5DT9 A;  1TUA A;  2CTE A;  3FAU A;  4DUY H;  4PDB A;  4DV5 H;  2OPU A;  2UXD H;  4AIM A;  2ANN A;  4KHP H;  4JI2 H;  1VIH A;  3OET A;  2E5L H;  2ZM6 H;  4OO1 G;  1IBM H;  1NXU A;  3OTO H;  4JYA H;  3NCV A;  5LMU H;  3UOE A;  1HR0 H;  4YHH H;  4DV1 H;  4NXN H;  5IWA H;  3V69 A;  4DUZ H;  3AEV B;  2UUA H;  2UXB H;  4JVH A;  2HH3 A;  1FJG H;  4NZT M;  4B8T A;  2UUB H;  2LTL A;  2O4C A;  1X9Z A;  2VQF H;  4DR6 H;  1S03 G;  1XMQ H;  5K36 G;  4LF4 H;  4E9J A;  2JVZ A;  4IFD G;  1HNZ H;  4OD6 A;  4BA1 I;  2UU9 H;  4JI7 H;  5JEA G;  4X64 H;  3T1H H;  4JI0 H;  1S20 A;  2CTJ A;  1KHM A;  2ZQE A;  2X06 A;  1ODH A;  1ZZI A;  1WVN A;  3KDG A;  2PY9 A;  4LFA H;  4FJS A;  4WAL A;  3KDK A;  4GKJ H;  1N33 H;  1X4M A;  1MSZ A;  2CTL A;  4JI3 H;  3J7A K;  1IBK H;  1XRH A;  4FJU A;  3RF2 A;  4DR4 H;  4AQY H;  4AM3 A;  4JI4 H;  2Y3M A;  2FMR A;  3EZJ A;  4DV4 H;  2JA9 A;  4DV7 H;  4DR5 H;  2JZX A;  1J5E H;  2PQU A;  2G8Y A;  1VBI A;  4NZR M;  4DR7 H;  4DV2 H;  1V8C A;  1VIG A;  4DV0 H;  1DTJ A;  2LRR A;  2A1S A;  2D9I A;  3GAB A;  4G08 A;  2JEA I;  5LMN H;  2QND A;  3GR5 A;  1ZTG A;  2LF0 A;  4LFC H;  1ZZJ A;  2Z0S A;  1UG8 A;  2CPQ A;  3L7Z C;  1IBL H;  1N36 H;  4JV5 H;  4LF5 H;  4K0K H;  1HNW H;  1Z2I A;  1SEI A;  3JAM W;  4NBQ A;  4DR1 H;  1I6U A;  2YQR A;  4X65 H;  2P2R A;  4LF8 H;  4NXM H;  4B3M H;  4DV3 H;  1AN7 A;  2HH2 A;  2OPV A;  5LL6 b;  1XNQ H;  4LF6 H;  2ANR A;  2UXC H;  4X66 H;  4DR2 H;  2LTM A;  2FFM A;  4H8A A; 
#chains in the Genus database with same CATH homology
 2JA9 A;  1WE8 A;  2JZX A;  1J5K A;  2PQU A;  1X4N A;  5C0X G;  5K36 G;  4QMF B;  3U1K A;  2DGR A;  1VIG A;  2CTK A;  1TUA A;  2CTE A;  1DTJ A;  4LIJ A;  2JVZ A;  2MJH A;  2CTF A;  4AM3 A;  4IFD G;  2OPU A;  4JVY A;  2NN6 G;  4AIM A;  4BA1 I;  2ANN A;  2JEA I;  5JEA G;  1VIH A;  2QND A;  4WAN A;  2CTJ A;  1ZTG A;  2JE6 I;  1KHM A;  4OO1 G;  1ZZJ A;  2CTM A;  2BL5 A;  2CPQ A;  2Z0S A;  3L7Z C;  1K1G A;  2JEB I;  1ZZI A;  1WVN A;  1ZZK A;  4BA2 I;  2PY9 A;  3V69 A;  4WAL A;  3VKE A;  3AEV B;  1EC6 A;  4NBQ A;  4JVH A;  1J4W A;  1DT4 A;  1X4M A;  2CTL A;  2YQR A;  2P2R A;  2HH3 A;  2AXY A;  2HH2 A;  2OPV A;  2E3U A;  4B8T A;  2ANR A;  2FMR A;  2BA0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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