3VKEA

Contribution of the first k-homology domain of poly(c)-binding protein 1 to its affinity and specificity for c-rich oligonucleotides
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
76
structure length
76
Chain Sequence
HMLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNSPERIITLTGPTNAIFKAFAMIIDKLEEDINSSW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
pubmed doi rcsb
molecule tags Dna binding protein/dna
source organism Homo sapiens
molecule keywords Poly(rC)-binding protein 1
total genus 23
structure length 76
sequence length 76
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 3vkeA00
2MJHA 2JVZA 2JZXA 4AM3A 2PQUA 2P2RA 3L7ZC 2CTMA 1TUAA 2CTLA 1KHMA 2CTJA 4AIMA 1K1GA 2BL5A 4NBQA 1VIHA 1WVNA 2AXYA 3U1KA 2ANRA 4JVYA 1EC6A 2CPQA 2CTEA 2E3UA 5JEAG 4WANA 2FMRA 4OO1G 2JEBI 2HH3A 4BA1I 3AEVB 2ANNA 2CTKA 1WE8A 2CTFA 2DGRA 2HH2A 2Z0SA 4LIJA 4QMFB 4B8TA 3VKEA 1ZZIA 5C0XG 1J4WA 1DT4A 2JEAI 1J5KA 4BA2I 2PY9A 2OPUA 4JVHA 1X4NA 1ZZKA 2NN6G 1X4MA 4WALA 1DTJA 2BA0A 1ZTGA 2YQRA 1ZZJA 2OPVA 4IFDG 2QNDA 3V69A 2JE6I 2JA9A 5K36G 1VIGA
chains in the Genus database with same CATH superfamily
2M6QA 1VBIA 2PQUA 4EC5A 1Z2IA 2CTMA 4LFBH 1N33H 4NZTM 1WHRA 2CTLA 2LTMA 1HNWH 4AIMA 4DV0H 3FAUA 4H8AA 5IWAH 1N34H 2BL5A 4NBQA 1I6UA 2UUAH 4LFCH 1I94H 4LF4H 3U1KA 2CTEA 4LF9H 2FMRA 4B3RH 2UUCH 2ANNA 2CTFA 4DUZH 1J4WA 1XNQH 5C0XG 3OTOH 3T1HH 4JI1H 1FKAH 2OPUA 2PY9A 1X4NA 4FJSA 5A2QW 4K0KH 4JI4H 2OPVA 2G8YA 3KDKA 1HR0H 3V69A 1J5EH 4X62H 1VIGA 3L7ZC 4X66H 2JVZA 2MJHA 2F4VH 4X65H 1PQXA 5FLXW 1SEIA 4B8CD 2P2RA 2UU9H 2ZQEA 2LTLA 3GR5A 4OD6A 1NXUA 4DV4H 2CTJA 3OSSD 1S20A 4LF5H 2VQEH 1N36H 4B3TH 1VIHA 4YY3H 4X64H 2ANRA 4GKKH 2CPQA 5JEAG 2E3UA 4NXNH 3UOEA 5DT9A 4DV3H 2HH3A 2O4CA 1WE8A 2CPMA 4JI0H 2CWFA 2JEAI 4B8TA 2D9IA 3VKEA 1DT4A 2K1HA 4DR1H 4DV1H 4DV2H 4DR4H 1V8CA 2NN6G 1X4MA 1IBLH 1UG8A 3J81W 1IBKH 2YQRA 2QNDA 4DV6H 4JYAH 2JE6I 4AQYH 5K36G 3J80W 4LF6H 2PT7G 2UXDH 2VKCA 4LFAH 1X9ZA 5LMUH 2HHHH 4OX9H 2Y3MA 3RF2A 1XMQH 1HNXH 4DR7H 1IBMH 2VQFH 3SB1A 4BA1I 3AEVB 4DR2H 2CWHA 2HH2A 3NCVA 2DGRA 4QMFB 4LIJA 4JI7H 2X06A 1ZZIA 2ZM6H 4BA2I 4OO1G 1N32H 4JI6H 3J7AK 3T1YH 1ZZKA 4JV5H 2FPHX 3KDGA 5BR8H 4WALA 4DR3H 1S03G 1ZZJA 3EZJA 1XMOH 2JZXA 4B3MH 4JI5H 4LF8H 1MSZA 2FFMA 5LMNH 2UUBH 1FJGH 3JAMW 4AM3A 5LL6b 1V9NA 4B3SH 3I0PA 1TUAA 4DR5H 1KHMA 4PDBA 3GKUA 4KHPH 1F0XA 4JI2H 1WVNA 2AXYA 2LF0A 5IT9W 2A1SA 3QD7X 4JVYA 1EC6A 4DV7H 3OETA 4WANA 4JI3H 1HNZH 4DUYH 1AN7A 2JEBI 2CTKA 2Z0SA 4DR6H 2UXCH 4OCHA 2M8WA 1J5KA 4NXMH 4JVHA 1WTJA 4NZRM 1ODHA 1XNRH 4E9JA 4G08A 1X0AA 4GKJH 1DTJA 2BA0A 1ZTGA 4JI8H 2UXBH 4YHHH 3GABA 4FJUA 2LRRA 4DV5H 2E5LH 4IFDG 1K1GA 2JA9A 1XRHA 4LF7H
chains in the Genus database with same CATH topology
2MJHA 2JVZA 2JZXA 4AM3A 2PQUA 2P2RA 3L7ZC 2CTMA 1TUAA 2CTLA 1KHMA 2CTJA 4AIMA 1K1GA 2BL5A 4NBQA 1VIHA 1WVNA 2AXYA 3U1KA 2ANRA 4JVYA 1EC6A 2CPQA 2CTEA 2E3UA 5JEAG 4WANA 2FMRA 4OO1G 2JEBI 2HH3A 4BA1I 3AEVB 2ANNA 2CTKA 1WE8A 2CTFA 2DGRA 2HH2A 2Z0SA 4LIJA 4QMFB 4B8TA 3VKEA 1ZZIA 5C0XG 1J4WA 1DT4A 2JEAI 1J5KA 4BA2I 2PY9A 2OPUA 4JVHA 1X4NA 1ZZKA 2NN6G 1X4MA 4WALA 1DTJA 2BA0A 1ZTGA 2YQRA 1ZZJA 2OPVA 4IFDG 2QNDA 3V69A 2JE6I 2JA9A 5K36G 1VIGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MJH A;  2JVZ A;  2JZX A;  4AM3 A;  2PQU A;  2P2R A;  3L7Z C;  2CTM A;  1TUA A;  2CTL A;  1KHM A;  2CTJ A;  4AIM A;  1K1G A;  2BL5 A;  4NBQ A;  1VIH A;  1WVN A;  2AXY A;  3U1K A;  2ANR A;  4JVY A;  1EC6 A;  2CPQ A;  2CTE A;  2E3U A;  5JEA G;  4WAN A;  2FMR A;  4OO1 G;  2JEB I;  2HH3 A;  4BA1 I;  3AEV B;  2ANN A;  2CTK A;  1WE8 A;  2CTF A;  2DGR A;  2HH2 A;  2Z0S A;  4LIJ A;  4QMF B;  4B8T A;  3VKE A;  1ZZI A;  5C0X G;  1J4W A;  1DT4 A;  2JEA I;  1J5K A;  4BA2 I;  2PY9 A;  2OPU A;  4JVH A;  1X4N A;  1ZZK A;  2NN6 G;  1X4M A;  4WAL A;  1DTJ A;  2BA0 A;  1ZTG A;  2YQR A;  1ZZJ A;  2OPV A;  4IFD G;  2QND A;  3V69 A;  2JE6 I;  2JA9 A;  5K36 G;  1VIG A; 
#chains in the Genus database with same CATH topology
 2M6Q A;  1VBI A;  2PQU A;  4EC5 A;  1Z2I A;  2CTM A;  4LFB H;  1N33 H;  4NZT M;  1WHR A;  2CTL A;  2LTM A;  1HNW H;  4AIM A;  4DV0 H;  3FAU A;  4H8A A;  5IWA H;  1N34 H;  2BL5 A;  4NBQ A;  1I6U A;  2UUA H;  4LFC H;  1I94 H;  4LF4 H;  3U1K A;  2CTE A;  4LF9 H;  2FMR A;  4B3R H;  2UUC H;  2ANN A;  2CTF A;  4DUZ H;  1J4W A;  1XNQ H;  5C0X G;  3OTO H;  3T1H H;  4JI1 H;  1FKA H;  2OPU A;  2PY9 A;  1X4N A;  4FJS A;  5A2Q W;  4K0K H;  4JI4 H;  2OPV A;  2G8Y A;  3KDK A;  1HR0 H;  3V69 A;  1J5E H;  4X62 H;  1VIG A;  3L7Z C;  4X66 H;  2JVZ A;  2MJH A;  2F4V H;  4X65 H;  1PQX A;  5FLX W;  1SEI A;  4B8C D;  2P2R A;  2UU9 H;  2ZQE A;  2LTL A;  3GR5 A;  4OD6 A;  1NXU A;  4DV4 H;  2CTJ A;  3OSS D;  1S20 A;  4LF5 H;  2VQE H;  1N36 H;  4B3T H;  1VIH A;  4YY3 H;  4X64 H;  2ANR A;  4GKK H;  2CPQ A;  5JEA G;  2E3U A;  4NXN H;  3UOE A;  5DT9 A;  4DV3 H;  2HH3 A;  2O4C A;  1WE8 A;  2CPM A;  4JI0 H;  2CWF A;  2JEA I;  4B8T A;  2D9I A;  3VKE A;  1DT4 A;  2K1H A;  4DR1 H;  4DV1 H;  4DV2 H;  4DR4 H;  1V8C A;  2NN6 G;  1X4M A;  1IBL H;  1UG8 A;  3J81 W;  1IBK H;  2YQR A;  2QND A;  4DV6 H;  4JYA H;  2JE6 I;  4AQY H;  5K36 G;  3J80 W;  4LF6 H;  2PT7 G;  2UXD H;  2VKC A;  4LFA H;  1X9Z A;  5LMU H;  2HHH H;  4OX9 H;  2Y3M A;  3RF2 A;  1XMQ H;  1HNX H;  4DR7 H;  1IBM H;  2VQF H;  3SB1 A;  4BA1 I;  3AEV B;  4DR2 H;  2CWH A;  2HH2 A;  3NCV A;  2DGR A;  4QMF B;  4LIJ A;  4JI7 H;  2X06 A;  1ZZI A;  2ZM6 H;  4BA2 I;  4OO1 G;  1N32 H;  4JI6 H;  3J7A K;  3T1Y H;  1ZZK A;  4JV5 H;  2FPH X;  3KDG A;  5BR8 H;  4WAL A;  4DR3 H;  1S03 G;  1ZZJ A;  3EZJ A;  1XMO H;  2JZX A;  4B3M H;  4JI5 H;  4LF8 H;  1MSZ A;  2FFM A;  5LMN H;  2UUB H;  1FJG H;  3JAM W;  4AM3 A;  5LL6 b;  1V9N A;  4B3S H;  3I0P A;  1TUA A;  4DR5 H;  1KHM A;  4PDB A;  3GKU A;  4KHP H;  1F0X A;  4JI2 H;  1WVN A;  2AXY A;  2LF0 A;  5IT9 W;  2A1S A;  3QD7 X;  4JVY A;  1EC6 A;  4DV7 H;  3OET A;  4WAN A;  4JI3 H;  1HNZ H;  4DUY H;  1AN7 A;  2JEB I;  2CTK A;  2Z0S A;  4DR6 H;  2UXC H;  4OCH A;  2M8W A;  1J5K A;  4NXM H;  4JVH A;  1WTJ A;  4NZR M;  1ODH A;  1XNR H;  4E9J A;  4G08 A;  1X0A A;  4GKJ H;  1DTJ A;  2BA0 A;  1ZTG A;  4JI8 H;  2UXB H;  4YHH H;  3GAB A;  4FJU A;  2LRR A;  4DV5 H;  2E5L H;  4IFD G;  1K1G A;  2JA9 A;  1XRH A;  4LF7 H; 
#chains in the Genus database with same CATH homology
 2MJH A;  2JVZ A;  2JZX A;  4AM3 A;  2PQU A;  2P2R A;  3L7Z C;  2CTM A;  1TUA A;  2CTL A;  1KHM A;  2CTJ A;  4AIM A;  1K1G A;  2BL5 A;  4NBQ A;  1VIH A;  1WVN A;  2AXY A;  3U1K A;  2ANR A;  4JVY A;  1EC6 A;  2CPQ A;  2CTE A;  2E3U A;  5JEA G;  4WAN A;  2FMR A;  4OO1 G;  2JEB I;  2HH3 A;  4BA1 I;  3AEV B;  2ANN A;  2CTK A;  1WE8 A;  2CTF A;  2DGR A;  2HH2 A;  2Z0S A;  4LIJ A;  4QMF B;  4B8T A;  3VKE A;  1ZZI A;  5C0X G;  1J4W A;  1DT4 A;  2JEA I;  1J5K A;  4BA2 I;  2PY9 A;  2OPU A;  4JVH A;  1X4N A;  1ZZK A;  2NN6 G;  1X4M A;  4WAL A;  1DTJ A;  2BA0 A;  1ZTG A;  2YQR A;  1ZZJ A;  2OPV A;  4IFD G;  2QND A;  3V69 A;  2JE6 I;  2JA9 A;  5K36 G;  1VIG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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