4B8TA

Rna binding protein solution structure of the third kh domain of ksrp in complex with the g-rich target sequence.
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
106
structure length
106
Chain Sequence
GAMAYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis
pubmed doi rcsb
molecule tags Transcription/rna
source organism Homo sapiens
molecule keywords KH-TYPE SPLICING REGULATORY PROTEIN
total genus 21
structure length 106
sequence length 106
ec nomenclature
pdb deposition date 2012-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 4b8tA00
1VIGA 2E3UA 2HH3A 1X4MA 1DT4A 1TUAA 2CTFA 2ANRA 1EC6A 4WANA 2CTKA 1ZZJA 4BA2I 1ZZKA 1ZZIA 2P2RA 4AM3A 2CTJA 1DTJA 5JEAG 2OPVA 1ZTGA 2PQUA 2CTLA 2JZXA 1J5KA 5C0XG 3AEVB 1WVNA 4IFDG 2JEAI 4OO1G 1WE8A 2DGRA 3L7ZC 4JVHA 4B8TA 2Z0SA 4BA1I 5K36G 4NBQA 4JVYA 2BA0A 2CTMA 1VIHA 3VKEA 1K1GA 1J4WA 2QNDA 4QMFB 2AXYA 2CPQA 2NN6G 2ANNA 2FMRA 4LIJA 2JVZA 2PY9A 2MJHA 2JEBI 4AIMA 2HH2A 2OPUA 2JE6I 3U1KA 4WALA 2CTEA 1KHMA 2YQRA 2BL5A 3V69A 1X4NA 2JA9A
chains in the Genus database with same CATH superfamily
4YHHH 1I94H 4DR1H 4JI3H 1X4MA 1TUAA 2CTFA 1EC6A 2CPMA 5A2QW 1FJGH 4GKKH 4AM3A 4DV7H 3J7AK 1DTJA 4PDBA 2PQUA 1ZTGA 4IFDG 2CTLA 3NCVA 4DV1H 4OO1G 1WVNA 2M6QA 5BR8H 2JEAI 4JVHA 3T1YH 5K36G 2F4VH 4JVYA 4DUZH 1VBIA 1X0AA 2BA0A 3GR5A 3VKEA 2UU9H 2AXYA 1IBLH 2E5LH 3J80W 4OX9H 4LIJA 4JI6H 4DV5H 4B3MH 1Z2IA 1XRHA 2FPHX 1F0XA 2HHHH 3EZJA 2CTEA 1HNWH 4X64H 2YQRA 1XMOH 1N33H 4DV0H 1X4NA 4B3SH 3FAUA 2O4CA 1FKAH 4JI8H 1IBKH 4JI1H 2FFMA 1MSZA 1PQXA 4JYAH 1ZZIA 5JEAG 5IT9W 3I0PA 4OD6A 1J5KA 2UUCH 4X66H 2M8WA 5LMUH 3KDKA 3L7ZC 4B8TA 4BA1I 4DV6H 4NBQA 1J4WA 2UXDH 4LF7H 4NZTM 2CPQA 2NN6G 2ANNA 2VKCA 2FMRA 3OSSD 2JVZA 1NXUA 5LMNH 2MJHA 2JEBI 4EC5A 4FJSA 4KHPH 2CWFA 2UXBH 3U1KA 2ZQEA 1KHMA 2VQEH 2BL5A 4NZRM 4OCHA 2JZXA 2JA9A 4JI2H 2UUBH 4JI7H 2VQFH 3QD7X 1VIGA 2HH3A 4NXMH 1DT4A 3T1HH 2LRRA 4DR3H 2ANRA 4LFCH 4WANA 2CTKA 1ZZJA 4BA2I 1WTJA 4DR4H 2CTJA 3JAMW 4DV3H 2OPVA 2G8YA 2D9IA 1HNXH 1S03G 3AEVB 5C0XG 4DV2H 4LF6H 5DT9A 4E9JA 2Z0SA 2K1HA 1HNZH 1N36H 4FJUA 4DR6H 4H8AA 4B8CD 4LFBH 5IWAH 3GKUA 1K1GA 1V9NA 2A1SA 1N32H 2QNDA 4G08A 4QMFB 4JI5H 2UXCH 1UG8A 1J5EH 4LF8H 1WHRA 1N34H 5FLXW 2ZM6H 2PT7G 2LF0A 1X9ZA 2UUAH 2PY9A 4B3RH 4K0KH 3OTOH 3KDGA 4AIMA 4DUYH 2OPUA 4WALA 2X06A 4GKJH 4JI0H 4B3TH 4LF5H 1HR0H 1V8CA 4DR5H 1IBMH 2E3UA 1I6UA 1AN7A 4X62H 3SB1A 1XNQH 3OETA 3RF2A 1ZZKA 2Y3MA 2P2RA 2LTMA 4AQYH 2CWHA 5LL6b 1WE8A 2DGRA 3J81W 4DR7H 2CTMA 4DV4H 1VIHA 4X65H 4LF9H 1S20A 2LTLA 1XMQH 4LF4H 3GABA 3UOEA 4YY3H 4NXNH 1SEIA 4LFAH 1ODHA 2HH2A 4DR2H 2JE6I 1XNRH 4JV5H 3V69A 4JI4H
chains in the Genus database with same CATH topology
1VIGA 2E3UA 2HH3A 1X4MA 1DT4A 1TUAA 2CTFA 2ANRA 1EC6A 4WANA 2CTKA 1ZZJA 4BA2I 1ZZKA 1ZZIA 2P2RA 4AM3A 2CTJA 1DTJA 5JEAG 2OPVA 1ZTGA 2PQUA 2CTLA 2JZXA 1J5KA 5C0XG 3AEVB 1WVNA 4IFDG 2JEAI 4OO1G 1WE8A 2DGRA 3L7ZC 4JVHA 4B8TA 2Z0SA 4BA1I 5K36G 4NBQA 4JVYA 2BA0A 2CTMA 1VIHA 3VKEA 1K1GA 1J4WA 2QNDA 4QMFB 2AXYA 2CPQA 2NN6G 2ANNA 2FMRA 4LIJA 2JVZA 2PY9A 2MJHA 2JEBI 4AIMA 2HH2A 2OPUA 2JE6I 3U1KA 4WALA 2CTEA 1KHMA 2YQRA 2BL5A 3V69A 1X4NA 2JA9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VIG A;  2E3U A;  2HH3 A;  1X4M A;  1DT4 A;  1TUA A;  2CTF A;  2ANR A;  1EC6 A;  4WAN A;  2CTK A;  1ZZJ A;  4BA2 I;  1ZZK A;  1ZZI A;  2P2R A;  4AM3 A;  2CTJ A;  1DTJ A;  5JEA G;  2OPV A;  1ZTG A;  2PQU A;  2CTL A;  2JZX A;  1J5K A;  5C0X G;  3AEV B;  1WVN A;  4IFD G;  2JEA I;  4OO1 G;  1WE8 A;  2DGR A;  3L7Z C;  4JVH A;  4B8T A;  2Z0S A;  4BA1 I;  5K36 G;  4NBQ A;  4JVY A;  2BA0 A;  2CTM A;  1VIH A;  3VKE A;  1K1G A;  1J4W A;  2QND A;  4QMF B;  2AXY A;  2CPQ A;  2NN6 G;  2ANN A;  2FMR A;  4LIJ A;  2JVZ A;  2PY9 A;  2MJH A;  2JEB I;  4AIM A;  2HH2 A;  2OPU A;  2JE6 I;  3U1K A;  4WAL A;  2CTE A;  1KHM A;  2YQR A;  2BL5 A;  3V69 A;  1X4N A;  2JA9 A; 
#chains in the Genus database with same CATH topology
 4YHH H;  1I94 H;  4DR1 H;  4JI3 H;  1X4M A;  1TUA A;  2CTF A;  1EC6 A;  2CPM A;  5A2Q W;  1FJG H;  4GKK H;  4AM3 A;  4DV7 H;  3J7A K;  1DTJ A;  4PDB A;  2PQU A;  1ZTG A;  4IFD G;  2CTL A;  3NCV A;  4DV1 H;  4OO1 G;  1WVN A;  2M6Q A;  5BR8 H;  2JEA I;  4JVH A;  3T1Y H;  5K36 G;  2F4V H;  4JVY A;  4DUZ H;  1VBI A;  1X0A A;  2BA0 A;  3GR5 A;  3VKE A;  2UU9 H;  2AXY A;  1IBL H;  2E5L H;  3J80 W;  4OX9 H;  4LIJ A;  4JI6 H;  4DV5 H;  4B3M H;  1Z2I A;  1XRH A;  2FPH X;  1F0X A;  2HHH H;  3EZJ A;  2CTE A;  1HNW H;  4X64 H;  2YQR A;  1XMO H;  1N33 H;  4DV0 H;  1X4N A;  4B3S H;  3FAU A;  2O4C A;  1FKA H;  4JI8 H;  1IBK H;  4JI1 H;  2FFM A;  1MSZ A;  1PQX A;  4JYA H;  1ZZI A;  5JEA G;  5IT9 W;  3I0P A;  4OD6 A;  1J5K A;  2UUC H;  4X66 H;  2M8W A;  5LMU H;  3KDK A;  3L7Z C;  4B8T A;  4BA1 I;  4DV6 H;  4NBQ A;  1J4W A;  2UXD H;  4LF7 H;  4NZT M;  2CPQ A;  2NN6 G;  2ANN A;  2VKC A;  2FMR A;  3OSS D;  2JVZ A;  1NXU A;  5LMN H;  2MJH A;  2JEB I;  4EC5 A;  4FJS A;  4KHP H;  2CWF A;  2UXB H;  3U1K A;  2ZQE A;  1KHM A;  2VQE H;  2BL5 A;  4NZR M;  4OCH A;  2JZX A;  2JA9 A;  4JI2 H;  2UUB H;  4JI7 H;  2VQF H;  3QD7 X;  1VIG A;  2HH3 A;  4NXM H;  1DT4 A;  3T1H H;  2LRR A;  4DR3 H;  2ANR A;  4LFC H;  4WAN A;  2CTK A;  1ZZJ A;  4BA2 I;  1WTJ A;  4DR4 H;  2CTJ A;  3JAM W;  4DV3 H;  2OPV A;  2G8Y A;  2D9I A;  1HNX H;  1S03 G;  3AEV B;  5C0X G;  4DV2 H;  4LF6 H;  5DT9 A;  4E9J A;  2Z0S A;  2K1H A;  1HNZ H;  1N36 H;  4FJU A;  4DR6 H;  4H8A A;  4B8C D;  4LFB H;  5IWA H;  3GKU A;  1K1G A;  1V9N A;  2A1S A;  1N32 H;  2QND A;  4G08 A;  4QMF B;  4JI5 H;  2UXC H;  1UG8 A;  1J5E H;  4LF8 H;  1WHR A;  1N34 H;  5FLX W;  2ZM6 H;  2PT7 G;  2LF0 A;  1X9Z A;  2UUA H;  2PY9 A;  4B3R H;  4K0K H;  3OTO H;  3KDG A;  4AIM A;  4DUY H;  2OPU A;  4WAL A;  2X06 A;  4GKJ H;  4JI0 H;  4B3T H;  4LF5 H;  1HR0 H;  1V8C A;  4DR5 H;  1IBM H;  2E3U A;  1I6U A;  1AN7 A;  4X62 H;  3SB1 A;  1XNQ H;  3OET A;  3RF2 A;  1ZZK A;  2Y3M A;  2P2R A;  2LTM A;  4AQY H;  2CWH A;  5LL6 b;  1WE8 A;  2DGR A;  3J81 W;  4DR7 H;  2CTM A;  4DV4 H;  1VIH A;  4X65 H;  4LF9 H;  1S20 A;  2LTL A;  1XMQ H;  4LF4 H;  3GAB A;  3UOE A;  4YY3 H;  4NXN H;  1SEI A;  4LFA H;  1ODH A;  2HH2 A;  4DR2 H;  2JE6 I;  1XNR H;  4JV5 H;  3V69 A;  4JI4 H; 
#chains in the Genus database with same CATH homology
 1VIG A;  2E3U A;  2HH3 A;  1X4M A;  1DT4 A;  1TUA A;  2CTF A;  2ANR A;  1EC6 A;  4WAN A;  2CTK A;  1ZZJ A;  4BA2 I;  1ZZK A;  1ZZI A;  2P2R A;  4AM3 A;  2CTJ A;  1DTJ A;  5JEA G;  2OPV A;  1ZTG A;  2PQU A;  2CTL A;  2JZX A;  1J5K A;  5C0X G;  3AEV B;  1WVN A;  4IFD G;  2JEA I;  4OO1 G;  1WE8 A;  2DGR A;  3L7Z C;  4JVH A;  4B8T A;  2Z0S A;  4BA1 I;  5K36 G;  4NBQ A;  4JVY A;  2BA0 A;  2CTM A;  1VIH A;  3VKE A;  1K1G A;  1J4W A;  2QND A;  4QMF B;  2AXY A;  2CPQ A;  2NN6 G;  2ANN A;  2FMR A;  4LIJ A;  2JVZ A;  2PY9 A;  2MJH A;  2JEB I;  4AIM A;  2HH2 A;  2OPU A;  2JE6 I;  3U1K A;  4WAL A;  2CTE A;  1KHM A;  2YQR A;  2BL5 A;  3V69 A;  1X4N A;  2JA9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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