4H8AA

Crystal structure of ureidoglycolate dehydrogenase in binary complex with nadh
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
337
structure length
337
Chain Sequence
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Ureidoglycolate dehydrogenase
total genus 113
structure length 337
sequence length 337
chains with identical sequence B
ec nomenclature ec 1.1.1.350: Ureidoglycolate dehydrogenase (NAD(+)).
pdb deposition date 2012-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 4h8aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 4h8aA02
2G8YA 1V9NA 1NXUA 4FJUA 1WTJA 3UOEA 1Z2IA 2X06A 4H8AA 2CWFA 3I0PA 1S20A 4FJSA 1X0AA 1XRHA 2CWHA 1VBIA
chains in the Genus database with same CATH superfamily
1ZZJA 2CTLA 2LTMA 4DR4H 1TUAA 1X4NA 2HH2A 2JEAI 4B3RH 4B8CD 2CTEA 2CTKA 2FFMA 2ZM6H 4JVHA 1ZZKA 1HR0H 4B8TA 5JEAG 5C0XG 2OPVA 1X4MA 3V69A 4JI4H 2O4CA 2VQFH 2LTLA 4NZTM 4GKKH 2AXYA 2Z0SA 1S03G 4DR3H 1KHMA 4JI5H 1N32H 1Z2IA 2LF0A 1PQXA 1IBKH 4B3MH 4YY3H 2UU9H 4DV7H 2PY9A 4KHPH 1XNRH 1MSZA 1N34H 4JI6H 4DV5H 4OCHA 1DTJA 5LMNH 4NXMH 1I6UA 2UXCH 1S20A 1J5KA 4BA1I 2JA9A 2UXDH 4AQYH 2CPMA 3RF2A 2A1SA 3GR5A 4NBQA 3T1YH 3VKEA 2UUAH 3L7ZC 2QNDA 4DR2H 3J7AK 4JYAH 2NN6G 1X0AA 4DR5H 1WHRA 4OX9H 4LF8H 5LL6b 4X64H 3JAMW 2BA0A 1N36H 2D9IA 1HNWH 4B3SH 3I0PA 2CTJA 3FAUA 4EC5A 1UG8A 4GKJH 5K36G 4LFCH 1J5EH 3EZJA 5FLXW 2JE6I 1J4WA 4X66H 4NZRM 1VBIA 2ZQEA 5BR8H 1XMQH 4FJUA 2CPQA 3J80W 2E3UA 1DT4A 4JI2H 1X9ZA 3GABA 4DV6H 4IFDG 3NCVA 3SB1A 2BL5A 2JZXA 2MJHA 2PQUA 1XNQH 4LFAH 4FJSA 2UUCH 4JVYA 4JI1H 1F0XA 3J81W 1XMOH 1WTJA 4WALA 4YHHH 4WANA 4X65H 1SEIA 2FMRA 2PT7G 3OETA 4X62H 1NXUA 2UUBH 1ODHA 1VIGA 1ZTGA 2E5LH 4LF6H 3AEVB 3OTOH 4JI0H 1ZZIA 3GKUA 2CTFA 4DV4H 2F4VH 4LF7H 2JEBI 1N33H 4QMFB 2HHHH 4LF9H 2CWFA 2CTMA 1AN7A 5IT9W 1V9NA 4K0KH 2JVZA 1IBMH 4DUZH 4OD6A 1I94H 2M8WA 4B3TH 2ANNA 1V8CA 4DV0H 2UXBH 4LF5H 2VKCA 2M6QA 5LMUH 4JI8H 4NXNH 4DR6H 1HNXH 3KDKA 4LF4H 4AM3A 4DR7H 2OPUA 1VIHA 4OO1G 1WE8A 1EC6A 2CWHA 3QD7X 4JI3H 4JI7H 4PDBA 2Y3MA 1FJGH 3OSSD 3UOEA 4E9JA 2LRRA 1HNZH 4LIJA 2FPHX 3T1HH 5A2QW 2HH3A 1XRHA 1FKAH 2ANRA 2G8YA 4LFBH 3KDGA 4DV3H 2X06A 4H8AA 4DV2H 4DV1H 5DT9A 1K1GA 3U1KA 4JV5H 1IBLH 4DR1H 4AIMA 2P2RA 2K1HA 4DUYH 4BA2I 1WVNA 2YQRA 2VQEH 5IWAH 4G08A 2DGRA
chains in the Genus database with same CATH topology
2G8YA 1V9NA 1NXUA 4FJUA 1WTJA 3UOEA 1Z2IA 2X06A 4H8AA 2CWFA 3I0PA 1S20A 4FJSA 1X0AA 1XRHA 2CWHA 1VBIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G8Y A;  1V9N A;  1NXU A;  4FJU A;  1WTJ A;  3UOE A;  1Z2I A;  2X06 A;  4H8A A;  2CWF A;  3I0P A;  1S20 A;  4FJS A;  1X0A A;  1XRH A;  2CWH A;  1VBI A; 
#chains in the Genus database with same CATH topology
 1ZZJ A;  2CTL A;  2LTM A;  4DR4 H;  1TUA A;  1X4N A;  2HH2 A;  2JEA I;  4B3R H;  4B8C D;  2CTE A;  2CTK A;  2FFM A;  2ZM6 H;  4JVH A;  1ZZK A;  1HR0 H;  4B8T A;  5JEA G;  5C0X G;  2OPV A;  1X4M A;  3V69 A;  4JI4 H;  2O4C A;  2VQF H;  2LTL A;  4NZT M;  4GKK H;  2AXY A;  2Z0S A;  1S03 G;  4DR3 H;  1KHM A;  4JI5 H;  1N32 H;  1Z2I A;  2LF0 A;  1PQX A;  1IBK H;  4B3M H;  4YY3 H;  2UU9 H;  4DV7 H;  2PY9 A;  4KHP H;  1XNR H;  1MSZ A;  1N34 H;  4JI6 H;  4DV5 H;  4OCH A;  1DTJ A;  5LMN H;  4NXM H;  1I6U A;  2UXC H;  1S20 A;  1J5K A;  4BA1 I;  2JA9 A;  2UXD H;  4AQY H;  2CPM A;  3RF2 A;  2A1S A;  3GR5 A;  4NBQ A;  3T1Y H;  3VKE A;  2UUA H;  3L7Z C;  2QND A;  4DR2 H;  3J7A K;  4JYA H;  2NN6 G;  1X0A A;  4DR5 H;  1WHR A;  4OX9 H;  4LF8 H;  5LL6 b;  4X64 H;  3JAM W;  2BA0 A;  1N36 H;  2D9I A;  1HNW H;  4B3S H;  3I0P A;  2CTJ A;  3FAU A;  4EC5 A;  1UG8 A;  4GKJ H;  5K36 G;  4LFC H;  1J5E H;  3EZJ A;  5FLX W;  2JE6 I;  1J4W A;  4X66 H;  4NZR M;  1VBI A;  2ZQE A;  5BR8 H;  1XMQ H;  4FJU A;  2CPQ A;  3J80 W;  2E3U A;  1DT4 A;  4JI2 H;  1X9Z A;  3GAB A;  4DV6 H;  4IFD G;  3NCV A;  3SB1 A;  2BL5 A;  2JZX A;  2MJH A;  2PQU A;  1XNQ H;  4LFA H;  4FJS A;  2UUC H;  4JVY A;  4JI1 H;  1F0X A;  3J81 W;  1XMO H;  1WTJ A;  4WAL A;  4YHH H;  4WAN A;  4X65 H;  1SEI A;  2FMR A;  2PT7 G;  3OET A;  4X62 H;  1NXU A;  2UUB H;  1ODH A;  1VIG A;  1ZTG A;  2E5L H;  4LF6 H;  3AEV B;  3OTO H;  4JI0 H;  1ZZI A;  3GKU A;  2CTF A;  4DV4 H;  2F4V H;  4LF7 H;  2JEB I;  1N33 H;  4QMF B;  2HHH H;  4LF9 H;  2CWF A;  2CTM A;  1AN7 A;  5IT9 W;  1V9N A;  4K0K H;  2JVZ A;  1IBM H;  4DUZ H;  4OD6 A;  1I94 H;  2M8W A;  4B3T H;  2ANN A;  1V8C A;  4DV0 H;  2UXB H;  4LF5 H;  2VKC A;  2M6Q A;  5LMU H;  4JI8 H;  4NXN H;  4DR6 H;  1HNX H;  3KDK A;  4LF4 H;  4AM3 A;  4DR7 H;  2OPU A;  1VIH A;  4OO1 G;  1WE8 A;  1EC6 A;  2CWH A;  3QD7 X;  4JI3 H;  4JI7 H;  4PDB A;  2Y3M A;  1FJG H;  3OSS D;  3UOE A;  4E9J A;  2LRR A;  1HNZ H;  4LIJ A;  2FPH X;  3T1H H;  5A2Q W;  2HH3 A;  1XRH A;  1FKA H;  2ANR A;  2G8Y A;  4LFB H;  3KDG A;  4DV3 H;  2X06 A;  4H8A A;  4DV2 H;  4DV1 H;  5DT9 A;  1K1G A;  3U1K A;  4JV5 H;  1IBL H;  4DR1 H;  4AIM A;  2P2R A;  2K1H A;  4DUY H;  4BA2 I;  1WVN A;  2YQR A;  2VQE H;  5IWA H;  4G08 A;  2DGR A; 
#chains in the Genus database with same CATH homology
 2G8Y A;  1V9N A;  1NXU A;  4FJU A;  1WTJ A;  3UOE A;  1Z2I A;  2X06 A;  4H8A A;  2CWF A;  3I0P A;  1S20 A;  4FJS A;  1X0A A;  1XRH A;  2CWH A;  1VBI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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