4H8AA

Crystal structure of ureidoglycolate dehydrogenase in binary complex with nadh
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
337
structure length
337
Chain Sequence
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Ureidoglycolate dehydrogenase
total genus 113
structure length 337
sequence length 337
chains with identical sequence B
ec nomenclature ec 1.1.1.350: Ureidoglycolate dehydrogenase (NAD(+)).
pdb deposition date 2012-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 4h8aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 4h8aA02
2G8YA 3I0PA 2X06A 1VBIA 4FJUA 1Z2IA 4FJSA 1NXUA 1XRHA 2CWHA 2CWFA 1S20A 1WTJA 4H8AA 1V9NA 3UOEA 1X0AA
chains in the Genus database with same CATH superfamily
2G8YA 4LF5H 4OCHA 5FLXW 5DT9A 1DT4A 1J4WA 4GKKH 4AIMA 4K0KH 4X62H 2VQEH 2E5LH 1SEIA 1S20A 1HNZH 2BL5A 3QD7X 5LL6b 2UXBH 1AN7A 4EC5A 2E3UA 1Z2IA 1TUAA 3KDGA 2NN6G 1IBMH 4IFDG 2CTJA 2PT7G 4LFBH 1WE8A 3GKUA 2DGRA 1DTJA 2FMRA 3AEVB 4LF9H 4JI7H 4JI4H 4OD6A 4JI5H 4DR2H 4JI2H 3OTOH 2JZXA 4X64H 2UXCH 4DV7H 1F0XA 4DV6H 5LMNH 4DV5H 4WALA 4DR5H 2MJHA 2QNDA 2Y3MA 2PY9A 3T1HH 2YQRA 4JVHA 5K36G 4JVYA 1S03G 1VIHA 1J5EH 1N33H 4DV0H 3L7ZC 2FPHX 1ZZJA 4LF6H 1ODHA 2A1SA 2ZM6H 3KDKA 4NZTM 2CTFA 2LTMA 3SB1A 3EZJA 3JAMW 1XMQH 4FJUA 1IBLH 4NXMH 4YY3H 3J81W 4AM3A 1ZZKA 1V9NA 4KHPH 1HR0H 4X66H 1X0AA 5JEAG 2JVZA 3OETA 2X06A 1N36H 4LFAH 4DV2H 1X4NA 2VKCA 4B8TA 1WVNA 2CWFA 5LMUH 1HNXH 4JV5H 1WHRA 1V8CA 5A2QW 2K1HA 1VBIA 4YHHH 4X65H 3VKEA 2HH3A 1EC6A 4DV3H 4AQYH 1N32H 2LTLA 4BA1I 3OSSD 2JA9A 2OPVA 4B3MH 2BA0A 1UG8A 4JI3H 1HNWH 5IT9W 4FJSA 2CTEA 2M8WA 4DR1H 1MSZA 2CPMA 4JI1H 4DR4H 4E9JA 1NXUA 3RF2A 2AXYA 2PQUA 4JI0H 5C0XG 2UUAH 1X9ZA 3T1YH 1XRHA 3J80W 1IBKH 2M6QA 1I94H 1K1GA 1VIGA 4LF7H 1N34H 2ANRA 4DUYH 4DR7H 2CWHA 3U1KA 4NBQA 2P2RA 3UOEA 2D9IA 2JEBI 1I6UA 3GR5A 3I0PA 4QMFB 3GABA 4OO1G 2F4VH 2UXDH 5IWAH 2OPUA 4NZRM 4G08A 3V69A 1XNRH 1J5KA 4DR6H 4JYAH 1X4MA 4OX9H 3J7AK 2LRRA 4DV1H 1WTJA 1XMOH 2CTLA 2HHHH 4DUZH 4WANA 1XNQH 2HH2A 2LF0A 4B3TH 4B3RH 1FJGH 4B8CD 2CPQA 2O4CA 1ZZIA 5BR8H 2UU9H 3FAUA 4B3SH 4JI8H 4LF4H 4BA2I 1FKAH 4PDBA 1PQXA 2JE6I 4GKJH 4LF8H 4NXNH 2UUBH 2FFMA 4H8AA 3NCVA 2UUCH 2JEAI 2CTKA 4JI6H 4DV4H 4DR3H 4LFCH 2CTMA 2ZQEA 1KHMA 4LIJA 1ZTGA 2Z0SA 2VQFH 2ANNA
chains in the Genus database with same CATH topology
2G8YA 3I0PA 2X06A 1VBIA 4FJUA 1Z2IA 4FJSA 1NXUA 1XRHA 2CWHA 2CWFA 1S20A 1WTJA 4H8AA 1V9NA 3UOEA 1X0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G8Y A;  3I0P A;  2X06 A;  1VBI A;  4FJU A;  1Z2I A;  4FJS A;  1NXU A;  1XRH A;  2CWH A;  2CWF A;  1S20 A;  1WTJ A;  4H8A A;  1V9N A;  3UOE A;  1X0A A; 
#chains in the Genus database with same CATH topology
 2G8Y A;  4LF5 H;  4OCH A;  5FLX W;  5DT9 A;  1DT4 A;  1J4W A;  4GKK H;  4AIM A;  4K0K H;  4X62 H;  2VQE H;  2E5L H;  1SEI A;  1S20 A;  1HNZ H;  2BL5 A;  3QD7 X;  5LL6 b;  2UXB H;  1AN7 A;  4EC5 A;  2E3U A;  1Z2I A;  1TUA A;  3KDG A;  2NN6 G;  1IBM H;  4IFD G;  2CTJ A;  2PT7 G;  4LFB H;  1WE8 A;  3GKU A;  2DGR A;  1DTJ A;  2FMR A;  3AEV B;  4LF9 H;  4JI7 H;  4JI4 H;  4OD6 A;  4JI5 H;  4DR2 H;  4JI2 H;  3OTO H;  2JZX A;  4X64 H;  2UXC H;  4DV7 H;  1F0X A;  4DV6 H;  5LMN H;  4DV5 H;  4WAL A;  4DR5 H;  2MJH A;  2QND A;  2Y3M A;  2PY9 A;  3T1H H;  2YQR A;  4JVH A;  5K36 G;  4JVY A;  1S03 G;  1VIH A;  1J5E H;  1N33 H;  4DV0 H;  3L7Z C;  2FPH X;  1ZZJ A;  4LF6 H;  1ODH A;  2A1S A;  2ZM6 H;  3KDK A;  4NZT M;  2CTF A;  2LTM A;  3SB1 A;  3EZJ A;  3JAM W;  1XMQ H;  4FJU A;  1IBL H;  4NXM H;  4YY3 H;  3J81 W;  4AM3 A;  1ZZK A;  1V9N A;  4KHP H;  1HR0 H;  4X66 H;  1X0A A;  5JEA G;  2JVZ A;  3OET A;  2X06 A;  1N36 H;  4LFA H;  4DV2 H;  1X4N A;  2VKC A;  4B8T A;  1WVN A;  2CWF A;  5LMU H;  1HNX H;  4JV5 H;  1WHR A;  1V8C A;  5A2Q W;  2K1H A;  1VBI A;  4YHH H;  4X65 H;  3VKE A;  2HH3 A;  1EC6 A;  4DV3 H;  4AQY H;  1N32 H;  2LTL A;  4BA1 I;  3OSS D;  2JA9 A;  2OPV A;  4B3M H;  2BA0 A;  1UG8 A;  4JI3 H;  1HNW H;  5IT9 W;  4FJS A;  2CTE A;  2M8W A;  4DR1 H;  1MSZ A;  2CPM A;  4JI1 H;  4DR4 H;  4E9J A;  1NXU A;  3RF2 A;  2AXY A;  2PQU A;  4JI0 H;  5C0X G;  2UUA H;  1X9Z A;  3T1Y H;  1XRH A;  3J80 W;  1IBK H;  2M6Q A;  1I94 H;  1K1G A;  1VIG A;  4LF7 H;  1N34 H;  2ANR A;  4DUY H;  4DR7 H;  2CWH A;  3U1K A;  4NBQ A;  2P2R A;  3UOE A;  2D9I A;  2JEB I;  1I6U A;  3GR5 A;  3I0P A;  4QMF B;  3GAB A;  4OO1 G;  2F4V H;  2UXD H;  5IWA H;  2OPU A;  4NZR M;  4G08 A;  3V69 A;  1XNR H;  1J5K A;  4DR6 H;  4JYA H;  1X4M A;  4OX9 H;  3J7A K;  2LRR A;  4DV1 H;  1WTJ A;  1XMO H;  2CTL A;  2HHH H;  4DUZ H;  4WAN A;  1XNQ H;  2HH2 A;  2LF0 A;  4B3T H;  4B3R H;  1FJG H;  4B8C D;  2CPQ A;  2O4C A;  1ZZI A;  5BR8 H;  2UU9 H;  3FAU A;  4B3S H;  4JI8 H;  4LF4 H;  4BA2 I;  1FKA H;  4PDB A;  1PQX A;  2JE6 I;  4GKJ H;  4LF8 H;  4NXN H;  2UUB H;  2FFM A;  4H8A A;  3NCV A;  2UUC H;  2JEA I;  2CTK A;  4JI6 H;  4DV4 H;  4DR3 H;  4LFC H;  2CTM A;  2ZQE A;  1KHM A;  4LIJ A;  1ZTG A;  2Z0S A;  2VQF H;  2ANN A; 
#chains in the Genus database with same CATH homology
 2G8Y A;  3I0P A;  2X06 A;  1VBI A;  4FJU A;  1Z2I A;  4FJS A;  1NXU A;  1XRH A;  2CWH A;  2CWF A;  1S20 A;  1WTJ A;  4H8A A;  1V9N A;  3UOE A;  1X0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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