4WALA

Crystal structure of selenomethionine msl5 protein in complex with rna at 2.2 a
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
127
structure length
127
Chain Sequence
PTKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCLIMADSEDKMQKGIKVCQNIMIKAVTSPEGQNDLKRGQLRELAELNGTLREDNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs.
pubmed doi rcsb
molecule tags Protein binding/rna
source organism Saccharomyces cerevisiae
molecule keywords Branchpoint-bridging protein
total genus 31
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2014-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 4walA00
1ZTGA 1DTJA 5JEAG 1ZZIA 1WE8A 2PQUA 4IFDG 2HH3A 2BA0A 2BL5A 3U1KA 1VIHA 2FMRA 2OPUA 1X4MA 2Z0SA 4QMFB 4BA1I 2HH2A 4BA2I 2NN6G 2E3UA 1TUAA 1ZZJA 2CTKA 2DGRA 2QNDA 2AXYA 2CTMA 4JVYA 1ZZKA 2ANNA 2JEBI 1EC6A 5K36G 2JEAI 4OO1G 2CTEA 1X4NA 4NBQA 1K1GA 1KHMA 1WVNA 1J5KA 2ANRA 2CPQA 4LIJA 2P2RA 2MJHA 3AEVB 2OPVA 4JVHA 4WANA 2CTFA 4AIMA 2JZXA 2PY9A 2CTJA 5C0XG 3L7ZC 1VIGA 4B8TA 2YQRA 3VKEA 1J4WA 4AM3A 4WALA 3V69A 2CTLA 2JE6I 2JVZA 1DT4A 2JA9A
chains in the Genus database with same CATH superfamily
3J80W 5LMNH 5JEAG 4LFAH 1ZZIA 4K0KH 4G08A 2PQUA 4KHPH 4GKKH 4DR4H 4DR7H 4LFBH 2BL5A 1VIHA 2FMRA 4LFCH 3FAUA 4BA2I 4BA1I 4X65H 4PDBA 2CPMA 1PQXA 2E3UA 2QNDA 4DR1H 1HNWH 5LL6b 4LF4H 2JEBI 2ANNA 4B3RH 1XNQH 5K36G 4JI5H 1KHMA 1X4NA 1K1GA 1WVNA 4X64H 3I0PA 2MJHA 4JVHA 3KDGA 4EC5A 2LTLA 4YHHH 2A1SA 4B8TA 1XRHA 2M6QA 4DV3H 5BR8H 4JI8H 3J81W 1IBMH 2FFMA 3V69A 5IT9W 2CWHA 2JVZA 1WHRA 4YY3H 1ZTGA 1Z2IA 3OTOH 2VKCA 4X62H 4DV5H 4JI3H 1V9NA 1NXUA 4LF6H 2OPUA 1S03G 4QMFB 5LMUH 1XMQH 1IBKH 4JVYA 2D9IA 1TUAA 3GR5A 4AQYH 2DGRA 2ZQEA 5DT9A 1ZZJA 2E5LH 1ZZKA 4DV1H 3UOEA 4OX9H 1EC6A 1N34H 2CTEA 2LF0A 4DV0H 1HNZH 1I94H 2ANRA 3OSSD 2CPQA 2VQFH 2PT7G 4LIJA 4DR3H 4DUZH 2OPVA 2M8WA 4JI1H 4X66H 4JI7H 1FJGH 5A2QW 3QD7X 4JI2H 3RF2A 5C0XG 2G8YA 3L7ZC 4JYAH 3GABA 1VBIA 4FJUA 2UUCH 1HNXH 1J4WA 3SB1A 1XMOH 1F0XA 1VIGA 2JE6I 1HR0H 4JI0H 3EZJA 1N32H 2JA9A 3T1YH 1DTJA 4FJSA 1MSZA 4IFDG 2HH3A 1I6UA 4DV6H 2BA0A 1XNRH 4B3MH 3T1HH 2NN6G 1SEIA 4E9JA 1UG8A 2CTMA 2K1HA 3KDKA 4DR2H 2HHHH 4GKJH 4B3SH 4OO1G 4B3TH 2UXDH 2P2RA 4WANA 4LF7H 3GKUA 4OCHA 4NXMH 4B8CD 4DUYH 4JI4H 1J5EH 4AIMA 2JZXA 2PY9A 1X9ZA 2Y3MA 2YQRA 4NXNH 1S20A 5IWAH 3JAMW 4DV2H 2LTMA 2CTLA 4DR6H 1DT4A 2LRRA 2CWFA 1WE8A 2FPHX 2O4CA 3OETA 3U1KA 1X4MA 2Z0SA 2HH2A 1N33H 1IBLH 1N36H 1ODHA 2CTKA 4OD6A 2AXYA 4DV7H 4DV4H 4NZRM 4LF5H 2JEAI 4NBQA 2VQEH 5FLXW 4LF9H 2ZM6H 1J5KA 2UXCH 4H8AA 3AEVB 2UUBH 1WTJA 4JI6H 1X0AA 2CTFA 1FKAH 2CTJA 2F4VH 2UU9H 4NZTM 3VKEA 4LF8H 3J7AK 3NCVA 4WALA 4AM3A 1V8CA 1AN7A 2X06A 4JV5H 2UUAH 4DR5H 2UXBH
chains in the Genus database with same CATH topology
1ZTGA 1DTJA 5JEAG 1ZZIA 1WE8A 2PQUA 4IFDG 2HH3A 2BA0A 2BL5A 3U1KA 1VIHA 2FMRA 2OPUA 1X4MA 2Z0SA 4QMFB 4BA1I 2HH2A 4BA2I 2NN6G 2E3UA 1TUAA 1ZZJA 2CTKA 2DGRA 2QNDA 2AXYA 2CTMA 4JVYA 1ZZKA 2ANNA 2JEBI 1EC6A 5K36G 2JEAI 4OO1G 2CTEA 1X4NA 4NBQA 1K1GA 1KHMA 1WVNA 1J5KA 2ANRA 2CPQA 4LIJA 2P2RA 2MJHA 3AEVB 2OPVA 4JVHA 4WANA 2CTFA 4AIMA 2JZXA 2PY9A 2CTJA 5C0XG 3L7ZC 1VIGA 4B8TA 2YQRA 3VKEA 1J4WA 4AM3A 4WALA 3V69A 2CTLA 2JE6I 2JVZA 1DT4A 2JA9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZTG A;  1DTJ A;  5JEA G;  1ZZI A;  1WE8 A;  2PQU A;  4IFD G;  2HH3 A;  2BA0 A;  2BL5 A;  3U1K A;  1VIH A;  2FMR A;  2OPU A;  1X4M A;  2Z0S A;  4QMF B;  4BA1 I;  2HH2 A;  4BA2 I;  2NN6 G;  2E3U A;  1TUA A;  1ZZJ A;  2CTK A;  2DGR A;  2QND A;  2AXY A;  2CTM A;  4JVY A;  1ZZK A;  2ANN A;  2JEB I;  1EC6 A;  5K36 G;  2JEA I;  4OO1 G;  2CTE A;  1X4N A;  4NBQ A;  1K1G A;  1KHM A;  1WVN A;  1J5K A;  2ANR A;  2CPQ A;  4LIJ A;  2P2R A;  2MJH A;  3AEV B;  2OPV A;  4JVH A;  4WAN A;  2CTF A;  4AIM A;  2JZX A;  2PY9 A;  2CTJ A;  5C0X G;  3L7Z C;  1VIG A;  4B8T A;  2YQR A;  3VKE A;  1J4W A;  4AM3 A;  4WAL A;  3V69 A;  2CTL A;  2JE6 I;  2JVZ A;  1DT4 A;  2JA9 A; 
#chains in the Genus database with same CATH topology
 3J80 W;  5LMN H;  5JEA G;  4LFA H;  1ZZI A;  4K0K H;  4G08 A;  2PQU A;  4KHP H;  4GKK H;  4DR4 H;  4DR7 H;  4LFB H;  2BL5 A;  1VIH A;  2FMR A;  4LFC H;  3FAU A;  4BA2 I;  4BA1 I;  4X65 H;  4PDB A;  2CPM A;  1PQX A;  2E3U A;  2QND A;  4DR1 H;  1HNW H;  5LL6 b;  4LF4 H;  2JEB I;  2ANN A;  4B3R H;  1XNQ H;  5K36 G;  4JI5 H;  1KHM A;  1X4N A;  1K1G A;  1WVN A;  4X64 H;  3I0P A;  2MJH A;  4JVH A;  3KDG A;  4EC5 A;  2LTL A;  4YHH H;  2A1S A;  4B8T A;  1XRH A;  2M6Q A;  4DV3 H;  5BR8 H;  4JI8 H;  3J81 W;  1IBM H;  2FFM A;  3V69 A;  5IT9 W;  2CWH A;  2JVZ A;  1WHR A;  4YY3 H;  1ZTG A;  1Z2I A;  3OTO H;  2VKC A;  4X62 H;  4DV5 H;  4JI3 H;  1V9N A;  1NXU A;  4LF6 H;  2OPU A;  1S03 G;  4QMF B;  5LMU H;  1XMQ H;  1IBK H;  4JVY A;  2D9I A;  1TUA A;  3GR5 A;  4AQY H;  2DGR A;  2ZQE A;  5DT9 A;  1ZZJ A;  2E5L H;  1ZZK A;  4DV1 H;  3UOE A;  4OX9 H;  1EC6 A;  1N34 H;  2CTE A;  2LF0 A;  4DV0 H;  1HNZ H;  1I94 H;  2ANR A;  3OSS D;  2CPQ A;  2VQF H;  2PT7 G;  4LIJ A;  4DR3 H;  4DUZ H;  2OPV A;  2M8W A;  4JI1 H;  4X66 H;  4JI7 H;  1FJG H;  5A2Q W;  3QD7 X;  4JI2 H;  3RF2 A;  5C0X G;  2G8Y A;  3L7Z C;  4JYA H;  3GAB A;  1VBI A;  4FJU A;  2UUC H;  1HNX H;  1J4W A;  3SB1 A;  1XMO H;  1F0X A;  1VIG A;  2JE6 I;  1HR0 H;  4JI0 H;  3EZJ A;  1N32 H;  2JA9 A;  3T1Y H;  1DTJ A;  4FJS A;  1MSZ A;  4IFD G;  2HH3 A;  1I6U A;  4DV6 H;  2BA0 A;  1XNR H;  4B3M H;  3T1H H;  2NN6 G;  1SEI A;  4E9J A;  1UG8 A;  2CTM A;  2K1H A;  3KDK A;  4DR2 H;  2HHH H;  4GKJ H;  4B3S H;  4OO1 G;  4B3T H;  2UXD H;  2P2R A;  4WAN A;  4LF7 H;  3GKU A;  4OCH A;  4NXM H;  4B8C D;  4DUY H;  4JI4 H;  1J5E H;  4AIM A;  2JZX A;  2PY9 A;  1X9Z A;  2Y3M A;  2YQR A;  4NXN H;  1S20 A;  5IWA H;  3JAM W;  4DV2 H;  2LTM A;  2CTL A;  4DR6 H;  1DT4 A;  2LRR A;  2CWF A;  1WE8 A;  2FPH X;  2O4C A;  3OET A;  3U1K A;  1X4M A;  2Z0S A;  2HH2 A;  1N33 H;  1IBL H;  1N36 H;  1ODH A;  2CTK A;  4OD6 A;  2AXY A;  4DV7 H;  4DV4 H;  4NZR M;  4LF5 H;  2JEA I;  4NBQ A;  2VQE H;  5FLX W;  4LF9 H;  2ZM6 H;  1J5K A;  2UXC H;  4H8A A;  3AEV B;  2UUB H;  1WTJ A;  4JI6 H;  1X0A A;  2CTF A;  1FKA H;  2CTJ A;  2F4V H;  2UU9 H;  4NZT M;  3VKE A;  4LF8 H;  3J7A K;  3NCV A;  4WAL A;  4AM3 A;  1V8C A;  1AN7 A;  2X06 A;  4JV5 H;  2UUA H;  4DR5 H;  2UXB H; 
#chains in the Genus database with same CATH homology
 1ZTG A;  1DTJ A;  5JEA G;  1ZZI A;  1WE8 A;  2PQU A;  4IFD G;  2HH3 A;  2BA0 A;  2BL5 A;  3U1K A;  1VIH A;  2FMR A;  2OPU A;  1X4M A;  2Z0S A;  4QMF B;  4BA1 I;  2HH2 A;  4BA2 I;  2NN6 G;  2E3U A;  1TUA A;  1ZZJ A;  2CTK A;  2DGR A;  2QND A;  2AXY A;  2CTM A;  4JVY A;  1ZZK A;  2ANN A;  2JEB I;  1EC6 A;  5K36 G;  2JEA I;  4OO1 G;  2CTE A;  1X4N A;  4NBQ A;  1K1G A;  1KHM A;  1WVN A;  1J5K A;  2ANR A;  2CPQ A;  4LIJ A;  2P2R A;  2MJH A;  3AEV B;  2OPV A;  4JVH A;  4WAN A;  2CTF A;  4AIM A;  2JZX A;  2PY9 A;  2CTJ A;  5C0X G;  3L7Z C;  1VIG A;  4B8T A;  2YQR A;  3VKE A;  1J4W A;  4AM3 A;  4WAL A;  3V69 A;  2CTL A;  2JE6 I;  2JVZ A;  1DT4 A;  2JA9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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