4WANA

Crystal structure of msl5 protein in complex with rna at 1.8 a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
124
structure length
124
Chain Sequence
PTKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCLIIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs.
pubmed doi rcsb
molecule tags Protein binding/rna
source organism Saccharomyces cerevisiae
molecule keywords Branchpoint-bridging protein
total genus 37
structure length 124
sequence length 124
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2014-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00013 KH_1 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1370.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 K Homology domain, type 1 4wanA00
2P2RA 2CTFA 5C0XG 2MJHA 1ZZJA 4WANA 2BL5A 2BA0A 2CTLA 2JEAI 1VIHA 2ANRA 1ZZKA 1X4MA 1TUAA 3V69A 2JA9A 2JZXA 2AXYA 4BA2I 2HH3A 2HH2A 2CTMA 2ANNA 1X4NA 1J5KA 4WALA 2PY9A 4JVHA 3U1KA 4BA1I 4LIJA 1K1GA 1ZTGA 1J4WA 1KHMA 2CTEA 2Z0SA 4AM3A 2QNDA 4JVYA 3AEVB 4QMFB 5K36G 1VIGA 2NN6G 3VKEA 1WE8A 4OO1G 2JVZA 2CTJA 2CTKA 2JEBI 4B8TA 1WVNA 2E3UA 2OPVA 2OPUA 1DTJA 4AIMA 2PQUA 2FMRA 3L7ZC 1DT4A 2CPQA 1ZZIA 4IFDG 4NBQA 2DGRA 2JE6I 1EC6A 5JEAG 2YQRA
chains in the Genus database with same CATH superfamily
2P2RA 4JI7H 1ZZJA 1NXUA 2X06A 5LMUH 3OETA 1XRHA 2UUAH 4YY3H 2VQFH 2ANRA 4BA2I 2E5LH 4LF8H 3OTOH 4DV0H 2ANNA 1X9ZA 3J7AK 4JVHA 4JI2H 1FKAH 4LIJA 3I0PA 1ZTGA 4FJUA 1WTJA 2CTEA 2Z0SA 5LL6b 1V9NA 5K36G 3JAMW 4DV2H 4JV5H 2CTJA 3AEVB 2G8YA 1VBIA 4AIMA 5A2QW 1ODHA 4DUZH 4OX9H 1N32H 5IT9W 5DT9A 4DV1H 3FAUA 2LF0A 3KDGA 2CWFA 4E9JA 4KHPH 2CTFA 4G08A 4B8CD 4DR3H 2BL5A 4X62H 2ZM6H 4NXNH 4GKKH 1WHRA 2JZXA 4DR4H 2UXCH 2HH2A 4DV5H 1XMOH 1J5KA 2PY9A 1HNZH 1XNRH 2VQEH 1VIGA 2O4CA 4LF6H 5FLXW 4LF9H 1IBLH 2OPUA 4LF5H 4DV6H 4B3TH 4DV7H 3J80W 2FMRA 4LFCH 3UOEA 1ZZIA 1J5EH 4NBQA 2DGRA 2K1HA 5JEAG 2YQRA 4FJSA 1V8CA 3T1YH 5C0XG 4DR5H 1HR0H 3QD7X 4JI0H 4DR2H 4LFBH 4JI4H 3OSSD 2UXDH 4K0KH 1X4MA 4DV3H 2JA9A 1N33H 4NZTM 1MSZA 2HH3A 2UUCH 2A1SA 4AQYH 3U1KA 4B3SH 1KHMA 2PT7G 3J81W 4AM3A 4YHHH 2F4VH 2LTMA 2M8WA 4X64H 4DV4H 1I94H 4LF4H 4JI6H 1SEIA 1N34H 2M6QA 4H8AA 4DR1H 1X0AA 1S20A 1WE8A 3VKEA 4B3MH 4B3RH 4DR6H 1WVNA 2E3UA 2CWHA 4X66H 4DUYH 4JI5H 4NXMH 3GKUA 2PQUA 1UG8A 1IBMH 4LF7H 1IBKH 4OCHA 2JE6I 3GR5A 2CPMA 1FJGH 3NCVA 1EC6A 4DR7H 4BA1I 1AN7A 2LTLA 4OD6A 2MJHA 2ZQEA 4GKJH 4EC5A 2VKCA 2BA0A 2CTLA 2JEAI 1VIHA 4JI1H 1ZZKA 1TUAA 3V69A 4X65H 2AXYA 4JI8H 4JYAH 4WANA 2FPHX 2CTMA 1Z2IA 2UUBH 1X4NA 4WALA 2FFMA 4LFAH 3KDKA 1K1GA 5BR8H 4JI3H 1I6UA 1J4WA 2UXBH 2QNDA 4JVYA 4NZRM 4QMFB 1F0XA 5LMNH 2NN6G 1PQXA 2D9IA 5IWAH 1N36H 1HNXH 2HHHH 1XNQH 4OO1G 2JVZA 2CTKA 2JEBI 4B8TA 2OPVA 2LRRA 3RF2A 2Y3MA 3SB1A 1DTJA 3T1HH 1S03G 3L7ZC 4PDBA 1DT4A 2CPQA 1HNWH 4IFDG 3EZJA 1XMQH 2UU9H 3GABA
chains in the Genus database with same CATH topology
2P2RA 2CTFA 5C0XG 2MJHA 1ZZJA 4WANA 2BL5A 2BA0A 2CTLA 2JEAI 1VIHA 2ANRA 1ZZKA 1X4MA 1TUAA 3V69A 2JA9A 2JZXA 2AXYA 4BA2I 2HH3A 2HH2A 2CTMA 2ANNA 1X4NA 1J5KA 4WALA 2PY9A 4JVHA 3U1KA 4BA1I 4LIJA 1K1GA 1ZTGA 1J4WA 1KHMA 2CTEA 2Z0SA 4AM3A 2QNDA 4JVYA 3AEVB 4QMFB 5K36G 1VIGA 2NN6G 3VKEA 1WE8A 4OO1G 2JVZA 2CTJA 2CTKA 2JEBI 4B8TA 1WVNA 2E3UA 2OPVA 2OPUA 1DTJA 4AIMA 2PQUA 2FMRA 3L7ZC 1DT4A 2CPQA 1ZZIA 4IFDG 4NBQA 2DGRA 2JE6I 1EC6A 5JEAG 2YQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P2R A;  2CTF A;  5C0X G;  2MJH A;  1ZZJ A;  4WAN A;  2BL5 A;  2BA0 A;  2CTL A;  2JEA I;  1VIH A;  2ANR A;  1ZZK A;  1X4M A;  1TUA A;  3V69 A;  2JA9 A;  2JZX A;  2AXY A;  4BA2 I;  2HH3 A;  2HH2 A;  2CTM A;  2ANN A;  1X4N A;  1J5K A;  4WAL A;  2PY9 A;  4JVH A;  3U1K A;  4BA1 I;  4LIJ A;  1K1G A;  1ZTG A;  1J4W A;  1KHM A;  2CTE A;  2Z0S A;  4AM3 A;  2QND A;  4JVY A;  3AEV B;  4QMF B;  5K36 G;  1VIG A;  2NN6 G;  3VKE A;  1WE8 A;  4OO1 G;  2JVZ A;  2CTJ A;  2CTK A;  2JEB I;  4B8T A;  1WVN A;  2E3U A;  2OPV A;  2OPU A;  1DTJ A;  4AIM A;  2PQU A;  2FMR A;  3L7Z C;  1DT4 A;  2CPQ A;  1ZZI A;  4IFD G;  4NBQ A;  2DGR A;  2JE6 I;  1EC6 A;  5JEA G;  2YQR A; 
#chains in the Genus database with same CATH topology
 2P2R A;  4JI7 H;  1ZZJ A;  1NXU A;  2X06 A;  5LMU H;  3OET A;  1XRH A;  2UUA H;  4YY3 H;  2VQF H;  2ANR A;  4BA2 I;  2E5L H;  4LF8 H;  3OTO H;  4DV0 H;  2ANN A;  1X9Z A;  3J7A K;  4JVH A;  4JI2 H;  1FKA H;  4LIJ A;  3I0P A;  1ZTG A;  4FJU A;  1WTJ A;  2CTE A;  2Z0S A;  5LL6 b;  1V9N A;  5K36 G;  3JAM W;  4DV2 H;  4JV5 H;  2CTJ A;  3AEV B;  2G8Y A;  1VBI A;  4AIM A;  5A2Q W;  1ODH A;  4DUZ H;  4OX9 H;  1N32 H;  5IT9 W;  5DT9 A;  4DV1 H;  3FAU A;  2LF0 A;  3KDG A;  2CWF A;  4E9J A;  4KHP H;  2CTF A;  4G08 A;  4B8C D;  4DR3 H;  2BL5 A;  4X62 H;  2ZM6 H;  4NXN H;  4GKK H;  1WHR A;  2JZX A;  4DR4 H;  2UXC H;  2HH2 A;  4DV5 H;  1XMO H;  1J5K A;  2PY9 A;  1HNZ H;  1XNR H;  2VQE H;  1VIG A;  2O4C A;  4LF6 H;  5FLX W;  4LF9 H;  1IBL H;  2OPU A;  4LF5 H;  4DV6 H;  4B3T H;  4DV7 H;  3J80 W;  2FMR A;  4LFC H;  3UOE A;  1ZZI A;  1J5E H;  4NBQ A;  2DGR A;  2K1H A;  5JEA G;  2YQR A;  4FJS A;  1V8C A;  3T1Y H;  5C0X G;  4DR5 H;  1HR0 H;  3QD7 X;  4JI0 H;  4DR2 H;  4LFB H;  4JI4 H;  3OSS D;  2UXD H;  4K0K H;  1X4M A;  4DV3 H;  2JA9 A;  1N33 H;  4NZT M;  1MSZ A;  2HH3 A;  2UUC H;  2A1S A;  4AQY H;  3U1K A;  4B3S H;  1KHM A;  2PT7 G;  3J81 W;  4AM3 A;  4YHH H;  2F4V H;  2LTM A;  2M8W A;  4X64 H;  4DV4 H;  1I94 H;  4LF4 H;  4JI6 H;  1SEI A;  1N34 H;  2M6Q A;  4H8A A;  4DR1 H;  1X0A A;  1S20 A;  1WE8 A;  3VKE A;  4B3M H;  4B3R H;  4DR6 H;  1WVN A;  2E3U A;  2CWH A;  4X66 H;  4DUY H;  4JI5 H;  4NXM H;  3GKU A;  2PQU A;  1UG8 A;  1IBM H;  4LF7 H;  1IBK H;  4OCH A;  2JE6 I;  3GR5 A;  2CPM A;  1FJG H;  3NCV A;  1EC6 A;  4DR7 H;  4BA1 I;  1AN7 A;  2LTL A;  4OD6 A;  2MJH A;  2ZQE A;  4GKJ H;  4EC5 A;  2VKC A;  2BA0 A;  2CTL A;  2JEA I;  1VIH A;  4JI1 H;  1ZZK A;  1TUA A;  3V69 A;  4X65 H;  2AXY A;  4JI8 H;  4JYA H;  4WAN A;  2FPH X;  2CTM A;  1Z2I A;  2UUB H;  1X4N A;  4WAL A;  2FFM A;  4LFA H;  3KDK A;  1K1G A;  5BR8 H;  4JI3 H;  1I6U A;  1J4W A;  2UXB H;  2QND A;  4JVY A;  4NZR M;  4QMF B;  1F0X A;  5LMN H;  2NN6 G;  1PQX A;  2D9I A;  5IWA H;  1N36 H;  1HNX H;  2HHH H;  1XNQ H;  4OO1 G;  2JVZ A;  2CTK A;  2JEB I;  4B8T A;  2OPV A;  2LRR A;  3RF2 A;  2Y3M A;  3SB1 A;  1DTJ A;  3T1H H;  1S03 G;  3L7Z C;  4PDB A;  1DT4 A;  2CPQ A;  1HNW H;  4IFD G;  3EZJ A;  1XMQ H;  2UU9 H;  3GAB A; 
#chains in the Genus database with same CATH homology
 2P2R A;  2CTF A;  5C0X G;  2MJH A;  1ZZJ A;  4WAN A;  2BL5 A;  2BA0 A;  2CTL A;  2JEA I;  1VIH A;  2ANR A;  1ZZK A;  1X4M A;  1TUA A;  3V69 A;  2JA9 A;  2JZX A;  2AXY A;  4BA2 I;  2HH3 A;  2HH2 A;  2CTM A;  2ANN A;  1X4N A;  1J5K A;  4WAL A;  2PY9 A;  4JVH A;  3U1K A;  4BA1 I;  4LIJ A;  1K1G A;  1ZTG A;  1J4W A;  1KHM A;  2CTE A;  2Z0S A;  4AM3 A;  2QND A;  4JVY A;  3AEV B;  4QMF B;  5K36 G;  1VIG A;  2NN6 G;  3VKE A;  1WE8 A;  4OO1 G;  2JVZ A;  2CTJ A;  2CTK A;  2JEB I;  4B8T A;  1WVN A;  2E3U A;  2OPV A;  2OPU A;  1DTJ A;  4AIM A;  2PQU A;  2FMR A;  3L7Z C;  1DT4 A;  2CPQ A;  1ZZI A;  4IFD G;  4NBQ A;  2DGR A;  2JE6 I;  1EC6 A;  5JEA G;  2YQR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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