1AHUA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with p-cresol
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 161
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1ahuA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1ahuA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1ahuA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1ahuA03
4JAYA 2EXRA 3C0PA 4BBYA 1F0XA 5AE2A 1DZNA 1V97A 3FW7A 3LAEA 4BC9A 4DNSA 1N63C 4HG0A 3EUB3 3NS1B 4UD8A 3DQ0A 2GQUA 5FXPA 2BVGA 4PWBA 1N5XA 1T3QC 2QKNA 1QLUA 1RM6B 5FXDA 1FFUC 3S1CA 1W1RA 1JRPA 1W1KA 2P3HA 5FXFA 3W8XA 3ETRB 3S1FA 4PVHA 3S1EA 3B9JB 1FIQB 2Q4WA 3TX1A 1I19A 1W1QA 2AXRA 4BCAA 2MBRA 2VFUA 4PVKA 2W3RA 2O3GA 2YVSA 1W1SA 2W3SA 3NVVB 5FXEA 3D2DA 3GSYA 5HQXA 1VAOA 1WVEA 2VFVA 4XLOA 3S1DA 2W54A 3W8WA 5G5HB 1FFVC 4PZFA 2OAIA 3JS8A 1AHUA 1SB3B 1HSKA 1N60C 1E8GA 4BC7A 1MBTA 3D2HA 3W8ZA 3I99A 4O95A 5AE3A 3VTEA 2BVFA 2VAOA 4ML8A 2PLSA 1E0YA 1E8HA 2GQTA 2RK5A 3BW7A 2BVHA 2P4PA 3AMZA 2E3TA 5ADZA 1W1OA 3NRZB 1MBBA 4JB1A 4ZOHB 2PLIA 4PWCA 3AM9A 3FW9A 3LLBA 1N61C 3D2JA 2VFRA 1JROA 5AE1A 1FO4A 3PM9A 3DEDA 4PVJA 5HHZA 1UXYA 2I0KA 2NQWA 3FW8A 2R2ZA 1W1JA 1N62C 1AHZA 1E8FA 2VFSA 1W1LA 4PYTA 3AN1A 1AHVA 2W55A 5HMRA 2VFTA 1WVFA 1W1MA 3TSJA 4PVEA 1QLTA 3FWAA 2P13A 1DIIA 3TSHA 1VDVA 3KJMA 5G5GB 1ZR6A 3HRDC 2QPMA 3SR6B 1WYGA 5D79A 2R8DA 2Q85A 1DIQA 1N5WC 3NVYB 4MLAA 4OALA 3NVZB 3NVWB 1ZXIC 4EC3A
chains in the Genus database with same CATH superfamily
4JAYA 3POPA 2EXRA 3C0PA 4BBYA 1F0XA 5AE2A 1DZNA 1V97A 3FW7A 3LAEA 5L6FA 4BC9A 4DNSA 1N63C 4HG0A 3EUB3 3NS1B 4UD8A 3RJ8A 3DQ0A 2GQUA 5FXPA 2BVGA 4PWBA 1N5XA 1T3QC 2QKNA 3RJAA 1QLUA 1RM6B 5FXDA 1FFUC 3S1CA 1W1RA 1JRPA 1W1KA 3EJEB 2P3HA 5FXFA 3W8XA 2UUVA 3ETRB 3S1FA 4PVHA 3S1EA 3B9JB 1FIQB 2Q4WA 3TX1A 1I19A 1W1QA 2AXRA 4BCAA 2Y3SA 2MBRA 2VFUA 4PVKA 2W3RA 2O3GA 2YVSA 1W1SA 2W3SA 3NVVB 5FXEA 3D2DA 3GSYA 5HQXA 2UUUA 1VAOA 1WVEA 2VFVA 4XLOA 3S1DA 2W54A 3W8WA 5G5HB 2IPIA 2WDWA 1FFVC 4PZFA 2OAIA 3JS8A 1AHUA 1SB3B 5I1VA 1HSKA 1N60C 1E8GA 4BC7A 1MBTA 3D2HA 3W8ZA 3I99A 4O95A 5AE3A 3VTEA 2BVFA 2VAOA 4ML8A 2PLSA 1E0YA 1E8HA 2GQTA 2RK5A 3BW7A 2BVHA 2P4PA 5L6GA 3HSUA 3AMZA 2E3TA 5ADZA 3EJDB 1W1OA 3NRZB 1MBBA 4JB1A 4ZOHB 2PLIA 4PWCA 5AWVA 3AM9A 3FW9A 3PQBA 2Y08A 3LLBA 1N61C 3D2JA 2VFRA 1JROA 5AE1A 1FO4A 3PM9A 3DEDA 4PVJA 5HHZA 1UXYA 2I0KA 2NQWA 3FW8A 2R2ZA 1W1JA 2Y4GA 1N62C 1AHZA 1E8FA 2VFSA 1W1LA 4PYTA 3AN1A 1AHVA 2W55A 5HMRA 2VFTA 1WVFA 1W1MA 3TSJA 4PVEA 1QLTA 3FWAA 2P13A 1DIIA 3TSHA 2Y3RA 1VDVA 3EJBB 3KJMA 5G5GB 1ZR6A 3HRDC 2QPMA 3SR6B 1WYGA 5K8EA 5D79A 2R8DA 2Q85A 1DIQA 1N5WC 3NVYB 4MLAA 4OALA 5I1WA 3NVZB 3NVWB 1ZXIC 4EC3A
chains in the Genus database with same CATH topology
4JAYA 3POPA 2EXRA 3C0PA 4BBYA 1F0XA 5AE2A 1DZNA 1V97A 3NVWB 3FW7A 3LAEA 5L6FA 4BC9A 4DNSA 1N63C 4HG0A 3EUB3 3NS1B 4UD8A 3RJ8A 3DQ0A 2GQUA 5FXPA 2BVGA 4PWBA 1N5XA 1T3QC 2QKNA 3RJAA 1QLUA 1RM6B 5FXDA 1FFUC 3S1CA 1W1RA 1JRPA 1W1KA 2P3HA 5FXFA 3W8XA 2UUVA 3ETRB 3S1FA 4PVHA 3S1EA 3B9JB 1FIQB 2Q4WA 3TX1A 1I19A 1W1QA 2AXRA 4BCAA 2Y3SA 2MBRA 2VFUA 4PVKA 2W3RA 2O3GA 2YVSA 1W1SA 2W3SA 3NVVB 5FXEA 3D2DA 3GSYA 5HQXA 2UUUA 1VAOA 1WVEA 2VFVA 4XLOA 3S1DA 2W54A 3W8WA 5G5HB 2IPIA 2WDWA 1FFVC 4PZFA 2OAIA 3JS8A 1AHUA 1SB3B 5I1VA 1HSKA 1N60C 1E8GA 4BC7A 1MBTA 3D2HA 3W8ZA 3I99A 4O95A 5AE3A 3VTEA 2BVFA 2VAOA 4ML8A 2PLSA 1E0YA 1E8HA 2GQTA 2RK5A 3BW7A 2BVHA 2P4PA 5L6GA 3AMZA 2E3TA 5ADZA 1W1OA 3NRZB 1MBBA 4JB1A 4ZOHB 2PLIA 4PWCA 5AWVA 3AM9A 3FW9A 3PQBA 2Y08A 3LLBA 1N61C 3D2JA 2VFRA 1JROA 5AE1A 1FO4A 3PM9A 3DEDA 4PVJA 5HHZA 1UXYA 2I0KA 2NQWA 3FW8A 2R2ZA 1W1JA 2Y4GA 1N62C 1AHZA 1E8FA 2VFSA 1W1LA 4PYTA 3AN1A 1AHVA 2W55A 5HMRA 2VFTA 1WVFA 1W1MA 3TSJA 4PVEA 1QLTA 3FWAA 2P13A 1DIIA 3TSHA 2Y3RA 1VDVA 3KJMA 5G5GB 1ZR6A 3HRDC 2QPMA 3SR6B 1WYGA 5K8EA 5D79A 2R8DA 2Q85A 1DIQA 1N5WC 3NVYB 4MLAA 4OALA 5I1WA 3NVZB 3HSUA 1ZXIC 4EC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JAY A;  2EXR A;  3C0P A;  4BBY A;  1F0X A;  5AE2 A;  1DZN A;  1V97 A;  3FW7 A;  3LAE A;  4BC9 A;  4DNS A;  1N63 C;  4HG0 A;  3EUB 3;  3NS1 B;  4UD8 A;  3DQ0 A;  2GQU A;  5FXP A;  2BVG A;  4PWB A;  1N5X A;  1T3Q C;  2QKN A;  1QLU A;  1RM6 B;  5FXD A;  1FFU C;  3S1C A;  1W1R A;  1JRP A;  1W1K A;  2P3H A;  5FXF A;  3W8X A;  3ETR B;  3S1F A;  4PVH A;  3S1E A;  3B9J B;  1FIQ B;  2Q4W A;  3TX1 A;  1I19 A;  1W1Q A;  2AXR A;  4BCA A;  2MBR A;  2VFU A;  4PVK A;  2W3R A;  2O3G A;  2YVS A;  1W1S A;  2W3S A;  3NVV B;  5FXE A;  3D2D A;  3GSY A;  5HQX A;  1VAO A;  1WVE A;  2VFV A;  4XLO A;  3S1D A;  2W54 A;  3W8W A;  5G5H B;  1FFV C;  4PZF A;  2OAI A;  3JS8 A;  1AHU A;  1SB3 B;  1HSK A;  1N60 C;  1E8G A;  4BC7 A;  1MBT A;  3D2H A;  3W8Z A;  3I99 A;  4O95 A;  5AE3 A;  3VTE A;  2BVF A;  2VAO A;  4ML8 A;  2PLS A;  1E0Y A;  1E8H A;  2GQT A;  2RK5 A;  3BW7 A;  2BVH A;  2P4P A;  3AMZ A;  2E3T A;  5ADZ A;  1W1O A;  3NRZ B;  1MBB A;  4JB1 A;  4ZOH B;  2PLI A;  4PWC A;  3AM9 A;  3FW9 A;  3LLB A;  1N61 C;  3D2J A;  2VFR A;  1JRO A;  5AE1 A;  1FO4 A;  3PM9 A;  3DED A;  4PVJ A;  5HHZ A;  1UXY A;  2I0K A;  2NQW A;  3FW8 A;  2R2Z A;  1W1J A;  1N62 C;  1AHZ A;  1E8F A;  2VFS A;  1W1L A;  4PYT A;  3AN1 A;  1AHV A;  2W55 A;  5HMR A;  2VFT A;  1WVF A;  1W1M A;  3TSJ A;  4PVE A;  1QLT A;  3FWA A;  2P13 A;  1DII A;  3TSH A;  1VDV A;  3KJM A;  5G5G B;  1ZR6 A;  3HRD C;  2QPM A;  3SR6 B;  1WYG A;  5D79 A;  2R8D A;  2Q85 A;  1DIQ A;  1N5W C;  3NVY B;  4MLA A;  4OAL A;  3NVZ B;  3NVW B;  1ZXI C;  4EC3 A; 
#chains in the Genus database with same CATH topology
 4JAY A;  3POP A;  2EXR A;  3C0P A;  4BBY A;  1F0X A;  5AE2 A;  1DZN A;  1V97 A;  3FW7 A;  3LAE A;  5L6F A;  4BC9 A;  4DNS A;  1N63 C;  4HG0 A;  3EUB 3;  3NS1 B;  4UD8 A;  3RJ8 A;  3DQ0 A;  2GQU A;  5FXP A;  2BVG A;  4PWB A;  1N5X A;  1T3Q C;  2QKN A;  3RJA A;  1QLU A;  1RM6 B;  5FXD A;  1FFU C;  3S1C A;  1W1R A;  1JRP A;  1W1K A;  3EJE B;  2P3H A;  5FXF A;  3W8X A;  2UUV A;  3ETR B;  3S1F A;  4PVH A;  3S1E A;  3B9J B;  1FIQ B;  2Q4W A;  3TX1 A;  1I19 A;  1W1Q A;  2AXR A;  4BCA A;  2Y3S A;  2MBR A;  2VFU A;  4PVK A;  2W3R A;  2O3G A;  2YVS A;  1W1S A;  2W3S A;  3NVV B;  5FXE A;  3D2D A;  3GSY A;  5HQX A;  2UUU A;  1VAO A;  1WVE A;  2VFV A;  4XLO A;  3S1D A;  2W54 A;  3W8W A;  5G5H B;  2IPI A;  2WDW A;  1FFV C;  4PZF A;  2OAI A;  3JS8 A;  1AHU A;  1SB3 B;  5I1V A;  1HSK A;  1N60 C;  1E8G A;  4BC7 A;  1MBT A;  3D2H A;  3W8Z A;  3I99 A;  4O95 A;  5AE3 A;  3VTE A;  2BVF A;  2VAO A;  4ML8 A;  2PLS A;  1E0Y A;  1E8H A;  2GQT A;  2RK5 A;  3BW7 A;  2BVH A;  2P4P A;  5L6G A;  3HSU A;  3AMZ A;  2E3T A;  5ADZ A;  3EJD B;  1W1O A;  3NRZ B;  1MBB A;  4JB1 A;  4ZOH B;  2PLI A;  4PWC A;  5AWV A;  3AM9 A;  3FW9 A;  3PQB A;  2Y08 A;  3LLB A;  1N61 C;  3D2J A;  2VFR A;  1JRO A;  5AE1 A;  1FO4 A;  3PM9 A;  3DED A;  4PVJ A;  5HHZ A;  1UXY A;  2I0K A;  2NQW A;  3FW8 A;  2R2Z A;  1W1J A;  2Y4G A;  1N62 C;  1AHZ A;  1E8F A;  2VFS A;  1W1L A;  4PYT A;  3AN1 A;  1AHV A;  2W55 A;  5HMR A;  2VFT A;  1WVF A;  1W1M A;  3TSJ A;  4PVE A;  1QLT A;  3FWA A;  2P13 A;  1DII A;  3TSH A;  2Y3R A;  1VDV A;  3EJB B;  3KJM A;  5G5G B;  1ZR6 A;  3HRD C;  2QPM A;  3SR6 B;  1WYG A;  5K8E A;  5D79 A;  2R8D A;  2Q85 A;  1DIQ A;  1N5W C;  3NVY B;  4MLA A;  4OAL A;  5I1W A;  3NVZ B;  3NVW B;  1ZXI C;  4EC3 A; 
#chains in the Genus database with same CATH homology
 4JAY A;  3POP A;  2EXR A;  3C0P A;  4BBY A;  1F0X A;  5AE2 A;  1DZN A;  1V97 A;  3NVW B;  3FW7 A;  3LAE A;  5L6F A;  4BC9 A;  4DNS A;  1N63 C;  4HG0 A;  3EUB 3;  3NS1 B;  4UD8 A;  3RJ8 A;  3DQ0 A;  2GQU A;  5FXP A;  2BVG A;  4PWB A;  1N5X A;  1T3Q C;  2QKN A;  3RJA A;  1QLU A;  1RM6 B;  5FXD A;  1FFU C;  3S1C A;  1W1R A;  1JRP A;  1W1K A;  2P3H A;  5FXF A;  3W8X A;  2UUV A;  3ETR B;  3S1F A;  4PVH A;  3S1E A;  3B9J B;  1FIQ B;  2Q4W A;  3TX1 A;  1I19 A;  1W1Q A;  2AXR A;  4BCA A;  2Y3S A;  2MBR A;  2VFU A;  4PVK A;  2W3R A;  2O3G A;  2YVS A;  1W1S A;  2W3S A;  3NVV B;  5FXE A;  3D2D A;  3GSY A;  5HQX A;  2UUU A;  1VAO A;  1WVE A;  2VFV A;  4XLO A;  3S1D A;  2W54 A;  3W8W A;  5G5H B;  2IPI A;  2WDW A;  1FFV C;  4PZF A;  2OAI A;  3JS8 A;  1AHU A;  1SB3 B;  5I1V A;  1HSK A;  1N60 C;  1E8G A;  4BC7 A;  1MBT A;  3D2H A;  3W8Z A;  3I99 A;  4O95 A;  5AE3 A;  3VTE A;  2BVF A;  2VAO A;  4ML8 A;  2PLS A;  1E0Y A;  1E8H A;  2GQT A;  2RK5 A;  3BW7 A;  2BVH A;  2P4P A;  5L6G A;  3AMZ A;  2E3T A;  5ADZ A;  1W1O A;  3NRZ B;  1MBB A;  4JB1 A;  4ZOH B;  2PLI A;  4PWC A;  5AWV A;  3AM9 A;  3FW9 A;  3PQB A;  2Y08 A;  3LLB A;  1N61 C;  3D2J A;  2VFR A;  1JRO A;  5AE1 A;  1FO4 A;  3PM9 A;  3DED A;  4PVJ A;  5HHZ A;  1UXY A;  2I0K A;  2NQW A;  3FW8 A;  2R2Z A;  1W1J A;  2Y4G A;  1N62 C;  1AHZ A;  1E8F A;  2VFS A;  1W1L A;  4PYT A;  3AN1 A;  1AHV A;  2W55 A;  5HMR A;  2VFT A;  1WVF A;  1W1M A;  3TSJ A;  4PVE A;  1QLT A;  3FWA A;  2P13 A;  1DII A;  3TSH A;  2Y3R A;  1VDV A;  3KJM A;  5G5G B;  1ZR6 A;  3HRD C;  2QPM A;  3SR6 B;  1WYG A;  5K8E A;  5D79 A;  2R8D A;  2Q85 A;  1DIQ A;  1N5W C;  3NVY B;  4MLA A;  4OAL A;  5I1W A;  3NVZ B;  3HSU A;  1ZXI C;  4EC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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