1W1LA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: phe454tyr mutant
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
555
structure length
550
Chain Sequence
b'EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDYIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 170
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1lA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1lA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1lA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1lA03
3W8XA 4JAYA 3D2JA 2PLSA 3LAEA 3NRZB 2O3GA 1N5WC 2Q85A 4EC3A 5AE3A 1AHUA 2P3HA 3PM9A 1E0YA 1SB3B 1QLTA 2RK5A 1QLUA 3I99A 3GSYA 1W1RA 3W8ZA 2QPMA 3FW7A 2PLIA 2BVFA 4O95A 5FXDA 1DZNA 4DNSA 2W3RA 1W1LA 2EXRA 3W8WA 1AHZA 1FIQB 3TX1A 5HMRA 1FFUC 3LLBA 3FW8A 4PYTA 1W1SA 1MBBA 2GQTA 3HRDC 3FWAA 5AE1A 1F0XA 2VFSA 3BW7A 4PZFA 3S1DA 1T3QC 1V97A 3NS1B 3ETRB 2R8DA 5FXEA 2Q4WA 1WVFA 3S1CA 1N61C 2W54A 3S1EA 1WVEA 3DEDA 3DQ0A 2VFUA 1JROA 3B9JB 2YVSA 1W1JA 4PVHA 5D79A 2BVGA 4ML8A 1DIQA 4BC9A 4PVKA 5FXFA 1FFVC 1RM6B 2I0KA 3C0PA 2VAOA 2VFVA 5FXPA 3EUB3 2W3SA 5ADZA 4OALA 1W1MA 4JB1A 2P4PA 3D2HA 5HHZA 3KJMA 4XLOA 2VFRA 1N62C 3VTEA 1ZR6A 3TSHA 4HG0A 1WYGA 4BC7A 2QKNA 4MLAA 1N60C 2OAIA 1W1KA 5HQXA 3NVVB 1E8HA 3D2DA 1MBTA 4UD8A 1VAOA 3JS8A 2P13A 2VFTA 4ZOHB 4BCAA 3NVWB 2MBRA 3NVZB 4BBYA 3AN1A 3AM9A 3FW9A 2GQUA 1N5XA 2W55A 3S1FA 2AXRA 3SR6B 2R2ZA 5AE2A 2BVHA 2NQWA 1W1QA 1VDVA 5G5HB 3NVYB 1ZXIC 1E8FA 4PVEA 1N63C 1W1OA 4PWCA 1JRPA 5G5GB 1AHVA 1FO4A 4PWBA 1UXYA 1E8GA 3TSJA 1DIIA 1I19A 2E3TA 3AMZA 1HSKA 4PVJA
chains in the Genus database with same CATH superfamily
3W8XA 4JAYA 3D2JA 2PLSA 3LAEA 2Y08A 3NRZB 2O3GA 1N5WC 2Q85A 4EC3A 5AE3A 1AHUA 2P3HA 3PM9A 1E0YA 1SB3B 1QLTA 2RK5A 1QLUA 3I99A 3GSYA 1W1RA 3W8ZA 2QPMA 3FW7A 3EJBB 2PLIA 2BVFA 4O95A 5FXDA 5I1VA 1DZNA 4DNSA 5I1WA 2Y3SA 2W3RA 1W1LA 2EXRA 5K8EA 3W8WA 1AHZA 1FIQB 3TX1A 5HMRA 1FFUC 3LLBA 3FW8A 4PYTA 1W1SA 1MBBA 2GQTA 3HRDC 3FWAA 5AE1A 1F0XA 2VFSA 3BW7A 4PZFA 3S1DA 1T3QC 1V97A 3NS1B 2Y4GA 3ETRB 2R8DA 5FXEA 2Q4WA 1WVFA 3S1CA 1N61C 2W54A 3S1EA 1WVEA 3DEDA 3DQ0A 2VFUA 3HSUA 1JROA 3PQBA 3B9JB 2YVSA 1W1JA 4PVHA 5D79A 2BVGA 4ML8A 1DIQA 4BC9A 4PVKA 5FXFA 1FFVC 1RM6B 2UUVA 2I0KA 3C0PA 2VAOA 2VFVA 5FXPA 5L6GA 3EUB3 2W3SA 5ADZA 4OALA 1W1MA 4JB1A 2P4PA 3D2HA 5AWVA 5HHZA 3RJAA 3KJMA 4XLOA 3EJEB 2VFRA 1N62C 3VTEA 1ZR6A 3TSHA 2WDWA 4HG0A 1WYGA 5L6FA 4BC7A 2QKNA 4MLAA 1N60C 2OAIA 2UUUA 1W1KA 5HQXA 3NVVB 1E8HA 2Y3RA 3D2DA 1MBTA 4UD8A 1VAOA 3JS8A 2P13A 2VFTA 3NVWB 4BCAA 4ZOHB 2MBRA 3NVZB 4BBYA 3POPA 3AN1A 3AM9A 3FW9A 2GQUA 1N5XA 2W55A 3S1FA 2AXRA 3SR6B 2R2ZA 5AE2A 2BVHA 2NQWA 1W1QA 3RJ8A 1VDVA 5G5HB 3NVYB 1ZXIC 1E8FA 4PVEA 1N63C 3EJDB 1W1OA 4PWCA 1JRPA 5G5GB 1AHVA 1FO4A 4PWBA 1UXYA 1E8GA 3TSJA 2IPIA 1DIIA 1I19A 2E3TA 3AMZA 1HSKA 4PVJA
chains in the Genus database with same CATH topology
3W8XA 4JAYA 3D2JA 2PLSA 3LAEA 2Y08A 3NRZB 2O3GA 1N5WC 2Q85A 4EC3A 5AE3A 1AHUA 2P3HA 3PM9A 1E0YA 1SB3B 1QLTA 2RK5A 1QLUA 3I99A 3GSYA 1W1RA 3W8ZA 2QPMA 3FW7A 2PLIA 2BVFA 4O95A 5FXDA 5I1VA 1DZNA 4DNSA 5I1WA 2Y3SA 2W3RA 1W1LA 2EXRA 5K8EA 3W8WA 1AHZA 1FIQB 3TX1A 5HMRA 1FFUC 3LLBA 3FW8A 4PYTA 1W1SA 1MBBA 2GQTA 3HRDC 3FWAA 5AE1A 1F0XA 2VFSA 3BW7A 4PZFA 3S1DA 1T3QC 1V97A 3NS1B 2Y4GA 3ETRB 2R8DA 5FXEA 2Q4WA 1WVFA 3S1CA 1N61C 2W54A 3S1EA 1WVEA 3DEDA 3DQ0A 2VFUA 3HSUA 1JROA 3PQBA 3B9JB 2YVSA 1W1JA 4PVHA 5D79A 2BVGA 4ML8A 1DIQA 4BC9A 4PVKA 5FXFA 1FFVC 1RM6B 2UUVA 2I0KA 3C0PA 2VAOA 2VFVA 5FXPA 5L6GA 3EUB3 2W3SA 5ADZA 4OALA 1W1MA 4JB1A 2P4PA 3D2HA 5AWVA 5HHZA 3RJAA 3KJMA 4XLOA 2VFRA 1N62C 3VTEA 1ZR6A 3TSHA 2WDWA 4HG0A 1WYGA 5L6FA 4BC7A 2QKNA 4MLAA 1N60C 2OAIA 2UUUA 1W1KA 5HQXA 3NVVB 1E8HA 2Y3RA 3D2DA 1MBTA 4UD8A 1VAOA 3JS8A 2P13A 2VFTA 4ZOHB 4BCAA 3NVWB 2MBRA 3NVZB 4BBYA 3POPA 3AN1A 3AM9A 3FW9A 2GQUA 1N5XA 2W55A 3S1FA 2AXRA 3SR6B 2R2ZA 5AE2A 2BVHA 2NQWA 1W1QA 3RJ8A 1VDVA 5G5HB 3NVYB 1ZXIC 1E8FA 4PVEA 1N63C 1W1OA 4PWCA 1JRPA 5G5GB 1AHVA 1FO4A 4PWBA 1UXYA 1E8GA 3TSJA 2IPIA 1DIIA 1I19A 2E3TA 3AMZA 1HSKA 4PVJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8X A;  4JAY A;  3D2J A;  2PLS A;  3LAE A;  3NRZ B;  2O3G A;  1N5W C;  2Q85 A;  4EC3 A;  5AE3 A;  1AHU A;  2P3H A;  3PM9 A;  1E0Y A;  1SB3 B;  1QLT A;  2RK5 A;  1QLU A;  3I99 A;  3GSY A;  1W1R A;  3W8Z A;  2QPM A;  3FW7 A;  2PLI A;  2BVF A;  4O95 A;  5FXD A;  1DZN A;  4DNS A;  2W3R A;  1W1L A;  2EXR A;  3W8W A;  1AHZ A;  1FIQ B;  3TX1 A;  5HMR A;  1FFU C;  3LLB A;  3FW8 A;  4PYT A;  1W1S A;  1MBB A;  2GQT A;  3HRD C;  3FWA A;  5AE1 A;  1F0X A;  2VFS A;  3BW7 A;  4PZF A;  3S1D A;  1T3Q C;  1V97 A;  3NS1 B;  3ETR B;  2R8D A;  5FXE A;  2Q4W A;  1WVF A;  3S1C A;  1N61 C;  2W54 A;  3S1E A;  1WVE A;  3DED A;  3DQ0 A;  2VFU A;  1JRO A;  3B9J B;  2YVS A;  1W1J A;  4PVH A;  5D79 A;  2BVG A;  4ML8 A;  1DIQ A;  4BC9 A;  4PVK A;  5FXF A;  1FFV C;  1RM6 B;  2I0K A;  3C0P A;  2VAO A;  2VFV A;  5FXP A;  3EUB 3;  2W3S A;  5ADZ A;  4OAL A;  1W1M A;  4JB1 A;  2P4P A;  3D2H A;  5HHZ A;  3KJM A;  4XLO A;  2VFR A;  1N62 C;  3VTE A;  1ZR6 A;  3TSH A;  4HG0 A;  1WYG A;  4BC7 A;  2QKN A;  4MLA A;  1N60 C;  2OAI A;  1W1K A;  5HQX A;  3NVV B;  1E8H A;  3D2D A;  1MBT A;  4UD8 A;  1VAO A;  3JS8 A;  2P13 A;  2VFT A;  4ZOH B;  4BCA A;  3NVW B;  2MBR A;  3NVZ B;  4BBY A;  3AN1 A;  3AM9 A;  3FW9 A;  2GQU A;  1N5X A;  2W55 A;  3S1F A;  2AXR A;  3SR6 B;  2R2Z A;  5AE2 A;  2BVH A;  2NQW A;  1W1Q A;  1VDV A;  5G5H B;  3NVY B;  1ZXI C;  1E8F A;  4PVE A;  1N63 C;  1W1O A;  4PWC A;  1JRP A;  5G5G B;  1AHV A;  1FO4 A;  4PWB A;  1UXY A;  1E8G A;  3TSJ A;  1DII A;  1I19 A;  2E3T A;  3AMZ A;  1HSK A;  4PVJ A; 
#chains in the Genus database with same CATH topology
 3W8X A;  4JAY A;  3D2J A;  2PLS A;  3LAE A;  2Y08 A;  3NRZ B;  2O3G A;  1N5W C;  2Q85 A;  4EC3 A;  5AE3 A;  1AHU A;  2P3H A;  3PM9 A;  1E0Y A;  1SB3 B;  1QLT A;  2RK5 A;  1QLU A;  3I99 A;  3GSY A;  1W1R A;  3W8Z A;  2QPM A;  3FW7 A;  3EJB B;  2PLI A;  2BVF A;  4O95 A;  5FXD A;  5I1V A;  1DZN A;  4DNS A;  5I1W A;  2Y3S A;  2W3R A;  1W1L A;  2EXR A;  5K8E A;  3W8W A;  1AHZ A;  1FIQ B;  3TX1 A;  5HMR A;  1FFU C;  3LLB A;  3FW8 A;  4PYT A;  1W1S A;  1MBB A;  2GQT A;  3HRD C;  3FWA A;  5AE1 A;  1F0X A;  2VFS A;  3BW7 A;  4PZF A;  3S1D A;  1T3Q C;  1V97 A;  3NS1 B;  2Y4G A;  3ETR B;  2R8D A;  5FXE A;  2Q4W A;  1WVF A;  3S1C A;  1N61 C;  2W54 A;  3S1E A;  1WVE A;  3DED A;  3DQ0 A;  2VFU A;  3HSU A;  1JRO A;  3PQB A;  3B9J B;  2YVS A;  1W1J A;  4PVH A;  5D79 A;  2BVG A;  4ML8 A;  1DIQ A;  4BC9 A;  4PVK A;  5FXF A;  1FFV C;  1RM6 B;  2UUV A;  2I0K A;  3C0P A;  2VAO A;  2VFV A;  5FXP A;  5L6G A;  3EUB 3;  2W3S A;  5ADZ A;  4OAL A;  1W1M A;  4JB1 A;  2P4P A;  3D2H A;  5AWV A;  5HHZ A;  3RJA A;  3KJM A;  4XLO A;  3EJE B;  2VFR A;  1N62 C;  3VTE A;  1ZR6 A;  3TSH A;  2WDW A;  4HG0 A;  1WYG A;  5L6F A;  4BC7 A;  2QKN A;  4MLA A;  1N60 C;  2OAI A;  2UUU A;  1W1K A;  5HQX A;  3NVV B;  1E8H A;  2Y3R A;  3D2D A;  1MBT A;  4UD8 A;  1VAO A;  3JS8 A;  2P13 A;  2VFT A;  3NVW B;  4BCA A;  4ZOH B;  2MBR A;  3NVZ B;  4BBY A;  3POP A;  3AN1 A;  3AM9 A;  3FW9 A;  2GQU A;  1N5X A;  2W55 A;  3S1F A;  2AXR A;  3SR6 B;  2R2Z A;  5AE2 A;  2BVH A;  2NQW A;  1W1Q A;  3RJ8 A;  1VDV A;  5G5H B;  3NVY B;  1ZXI C;  1E8F A;  4PVE A;  1N63 C;  3EJD B;  1W1O A;  4PWC A;  1JRP A;  5G5G B;  1AHV A;  1FO4 A;  4PWB A;  1UXY A;  1E8G A;  3TSJ A;  2IPI A;  1DII A;  1I19 A;  2E3T A;  3AMZ A;  1HSK A;  4PVJ A; 
#chains in the Genus database with same CATH homology
 3W8X A;  4JAY A;  3D2J A;  2PLS A;  3LAE A;  2Y08 A;  3NRZ B;  2O3G A;  1N5W C;  2Q85 A;  4EC3 A;  5AE3 A;  1AHU A;  2P3H A;  3PM9 A;  1E0Y A;  1SB3 B;  1QLT A;  2RK5 A;  1QLU A;  3I99 A;  3GSY A;  1W1R A;  3W8Z A;  2QPM A;  3FW7 A;  2PLI A;  2BVF A;  4O95 A;  5FXD A;  5I1V A;  1DZN A;  4DNS A;  5I1W A;  2Y3S A;  2W3R A;  1W1L A;  2EXR A;  5K8E A;  3W8W A;  1AHZ A;  1FIQ B;  3TX1 A;  5HMR A;  1FFU C;  3LLB A;  3FW8 A;  4PYT A;  1W1S A;  1MBB A;  2GQT A;  3HRD C;  3FWA A;  5AE1 A;  1F0X A;  2VFS A;  3BW7 A;  4PZF A;  3S1D A;  1T3Q C;  1V97 A;  3NS1 B;  2Y4G A;  3ETR B;  2R8D A;  5FXE A;  2Q4W A;  1WVF A;  3S1C A;  1N61 C;  2W54 A;  3S1E A;  1WVE A;  3DED A;  3DQ0 A;  2VFU A;  3HSU A;  1JRO A;  3PQB A;  3B9J B;  2YVS A;  1W1J A;  4PVH A;  5D79 A;  2BVG A;  4ML8 A;  1DIQ A;  4BC9 A;  4PVK A;  5FXF A;  1FFV C;  1RM6 B;  2UUV A;  2I0K A;  3C0P A;  2VAO A;  2VFV A;  5FXP A;  5L6G A;  3EUB 3;  2W3S A;  5ADZ A;  4OAL A;  1W1M A;  4JB1 A;  2P4P A;  3D2H A;  5AWV A;  5HHZ A;  3RJA A;  3KJM A;  4XLO A;  2VFR A;  1N62 C;  3VTE A;  1ZR6 A;  3TSH A;  2WDW A;  4HG0 A;  1WYG A;  5L6F A;  4BC7 A;  2QKN A;  4MLA A;  1N60 C;  2OAI A;  2UUU A;  1W1K A;  5HQX A;  3NVV B;  1E8H A;  2Y3R A;  3D2D A;  1MBT A;  4UD8 A;  1VAO A;  3JS8 A;  2P13 A;  2VFT A;  4ZOH B;  4BCA A;  3NVW B;  2MBR A;  3NVZ B;  4BBY A;  3POP A;  3AN1 A;  3AM9 A;  3FW9 A;  2GQU A;  1N5X A;  2W55 A;  3S1F A;  2AXR A;  3SR6 B;  2R2Z A;  5AE2 A;  2BVH A;  2NQW A;  1W1Q A;  3RJ8 A;  1VDV A;  5G5H B;  3NVY B;  1ZXI C;  1E8F A;  4PVE A;  1N63 C;  1W1O A;  4PWC A;  1JRP A;  5G5G B;  1AHV A;  1FO4 A;  4PWB A;  1UXY A;  1E8G A;  3TSJ A;  2IPI A;  1DII A;  1I19 A;  2E3T A;  3AMZ A;  1HSK A;  4PVJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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