2I0KA

Cholesterol oxidase from brevibacterium sterolicum- his121ala mutant
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
556
structure length
536
Chain Sequence
APLPTPPNFPNDIALFQQAYQNWSKEIMLDATWVCSPKTPQDVVRLANWAHEHDYKIRPRGAMAGWTPLTVEKGANVEKVILADTMTHLNGITVNTGGPVATVTAGAGASIEAIVTELQKHDLGWANLPAPGVLSIGGALAVNAHGAALPAVGQTTLPGHTYGSLSNLVTELTAVVWNGTTYALETYQRNDPRITPLLTNLGRCFLTSVTMQAGPNFRQRCQSYTDIPWRELFAPKGADGRTFEKFVAESGGAEAIWYPFTEKPWMKVWTVSGKPPQAREVSGPYNYIFSDNLPEPITDMIGAINAGNPGIAPLFGPAMYEITKLGLAATNANDIWGWSKDVQFYIKATTLRLTEGGGAVVTSRANIATVINDFTEWFHERIEFYRAKGEFPLNGPVEIRCCGLDQAADVKVPSVGPPTISATRPRPDHPDWDVAIWLNVLGVPGTPGMFEFYREMEQWMRSHYNNDDATFRPEWSKGWAFGPDPYTDNDIVTNKMRATYIEGVPTTENWDTARARYNQIDPHRVFTNGFMDKLLP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords Oxidoreductase
publication title Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.
pubmed doi rcsb
source organism Brevibacterium sterolicum
total genus 175
structure length 536
sequence length 556
ec nomenclature ec 1.1.3.6: Cholesterol oxidase.
pdb deposition date 2006-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF09129 Chol_subst-bind Cholesterol oxidase, substrate-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2i0kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2i0kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2i0kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2i0kA03
2P13A 1N5WC 4BBYA 5AE1A 3W8ZA 5HQXA 4ML8A 4PWBA 1ZR6A 3LLBA 4BCAA 3TX1A 5ADZA 1VAOA 5AE3A 2GQUA 5D79A 3W8XA 3NVVB 1WVFA 3FWAA 4ZOHB 1MBBA 1JRPA 1N63C 1JROA 4O95A 3I99A 2YVSA 1QLUA 1ZXIC 2EXRA 3VTEA 4PYTA 3W8WA 3AMZA 4XLOA 2W3RA 3EUB3 2R8DA 1FIQB 1FO4A 5AE2A 3NVZB 4PVHA 1SB3B 1AHVA 4PVJA 1DZNA 3B9JB 3TSJA 1V97A 1T3QC 2W54A 3FW9A 2O3GA 2W55A 3S1EA 1DIIA 3LAEA 2BVFA 3D2JA 3D2HA 1I19A 2VFSA 3D2DA 3ETRB 2VFTA 4EC3A 5FXFA 1N61C 2MBRA 3C0PA 1FFUC 2GQTA 3PM9A 3BW7A 2Q4WA 1DIQA 3FW8A 3S1DA 5HHZA 3JS8A 1VDVA 1RM6B 1F0XA 1W1MA 1W1OA 1WYGA 4UD8A 2VFRA 4PVKA 2PLSA 3S1FA 2I0KA 2E3TA 4PVEA 1MBTA 2R2ZA 1W1QA 3NVYB 4JB1A 1N62C 2BVHA 3KJMA 2P3HA 3DQ0A 4JAYA 3FW7A 1FFVC 4MLAA 5G5HB 1UXYA 3HRDC 3S1CA 4DNSA 2PLIA 3SR6B 2P4PA 3DEDA 4PWCA 1N60C 1W1KA 1E0YA 2VAOA 3NS1B 3GSYA 1AHZA 3NVWB 2W3SA 4PZFA 4BC7A 1QLTA 2RK5A 5FXDA 2VFVA 1E8GA 4BC9A 2QKNA 5FXEA 1W1SA 4HG0A 2Q85A 3AN1A 3NRZB 2QPMA 2AXRA 1N5XA 2OAIA 5G5GB 1W1RA 1E8FA 1E8HA 1W1LA 5HMRA 3AM9A 1WVEA 4OALA 2NQWA 1HSKA 2VFUA 1W1JA 5FXPA 3TSHA 1AHUA 2BVGA
chains in the Genus database with same CATH superfamily
2P13A 1N5WC 5K8EA 4BBYA 5AE1A 3W8ZA 5HQXA 4ML8A 4PWBA 1ZR6A 3LLBA 4BCAA 2UUVA 3TX1A 5ADZA 1VAOA 5AE3A 2GQUA 3EJDB 5D79A 3W8XA 3NVVB 2Y3SA 1WVFA 3FWAA 4ZOHB 1MBBA 3EJEB 1JRPA 1N63C 1JROA 3PQBA 5I1WA 4O95A 3I99A 2YVSA 1QLUA 1ZXIC 2EXRA 3VTEA 4PYTA 3POPA 3W8WA 3AMZA 3RJ8A 4XLOA 2W3RA 3EUB3 2R8DA 1FIQB 1FO4A 5AE2A 3NVZB 4PVHA 1SB3B 2Y3RA 1AHVA 4PVJA 1DZNA 3B9JB 3TSJA 1V97A 2IPIA 1T3QC 2W54A 3FW9A 5AWVA 2O3GA 2W55A 3S1EA 1DIIA 3LAEA 2BVFA 3D2JA 3D2HA 1I19A 2VFSA 3D2DA 3EJBB 2VFTA 3ETRB 4EC3A 5FXFA 1N61C 2MBRA 3C0PA 1FFUC 2GQTA 3PM9A 3BW7A 2Q4WA 1DIQA 3FW8A 3S1DA 5HHZA 3JS8A 1VDVA 1RM6B 1F0XA 1W1MA 1W1OA 3HSUA 1WYGA 4UD8A 2VFRA 4PVKA 2PLSA 3S1FA 2I0KA 2E3TA 2UUUA 4PVEA 1MBTA 5L6FA 2R2ZA 1W1QA 3NVYB 4JB1A 5L6GA 2Y08A 1N62C 2BVHA 3KJMA 2P3HA 3DQ0A 4JAYA 3FW7A 1FFVC 4MLAA 5G5HB 1UXYA 3HRDC 3S1CA 4DNSA 2PLIA 3SR6B 2P4PA 3DEDA 4PWCA 1N60C 1W1KA 1E0YA 2VAOA 3RJAA 3NS1B 3GSYA 1AHZA 3NVWB 2W3SA 4PZFA 4BC7A 1QLTA 2RK5A 5FXDA 2VFVA 1E8GA 4BC9A 2QKNA 5FXEA 1W1SA 4HG0A 2Q85A 3AN1A 3NRZB 2QPMA 2AXRA 1N5XA 2OAIA 5I1VA 5G5GB 1W1RA 2WDWA 2Y4GA 1E8FA 1E8HA 1W1LA 5HMRA 3AM9A 1WVEA 4OALA 2NQWA 1HSKA 2VFUA 1W1JA 5FXPA 3TSHA 1AHUA 2BVGA
chains in the Genus database with same CATH topology
2P13A 1N5WC 5K8EA 4BBYA 5AE1A 3W8ZA 5HQXA 4ML8A 4PWBA 1ZR6A 3LLBA 4BCAA 2UUVA 3TX1A 5ADZA 1VAOA 5AE3A 2GQUA 5D79A 3W8XA 3NVVB 2Y3SA 1WVFA 3FWAA 4ZOHB 1MBBA 1JRPA 5I1WA 1N63C 1JROA 3PQBA 4O95A 3I99A 2YVSA 1QLUA 1ZXIC 2EXRA 3VTEA 4PYTA 3POPA 3W8WA 3AMZA 3RJ8A 4XLOA 2W3RA 3EUB3 2R8DA 1FIQB 1FO4A 5AE2A 3NVZB 4PVHA 1SB3B 2Y3RA 1AHVA 4PVJA 1DZNA 3B9JB 3TSJA 1V97A 2IPIA 1T3QC 2W54A 3FW9A 5AWVA 2O3GA 2W55A 3S1EA 1DIIA 3LAEA 2BVFA 3D2JA 3D2HA 1I19A 2VFSA 3D2DA 3ETRB 2VFTA 4EC3A 5FXFA 1N61C 2MBRA 3C0PA 1FFUC 2GQTA 3PM9A 3BW7A 2Q4WA 1DIQA 3FW8A 3S1DA 5HHZA 3JS8A 1VDVA 1RM6B 1F0XA 1W1MA 1W1OA 3HSUA 1WYGA 4UD8A 2VFRA 4PVKA 2PLSA 3S1FA 2I0KA 2E3TA 2UUUA 4PVEA 1MBTA 5L6FA 2R2ZA 1W1QA 3NVYB 4JB1A 5L6GA 2Y08A 1N62C 2BVHA 3KJMA 2P3HA 3DQ0A 4JAYA 3FW7A 1FFVC 4MLAA 5G5HB 1UXYA 3HRDC 3S1CA 4DNSA 2PLIA 3SR6B 2P4PA 3DEDA 4PWCA 1N60C 1W1KA 1E0YA 2VAOA 3RJAA 3NS1B 3GSYA 1AHZA 3NVWB 2W3SA 4PZFA 4BC7A 1QLTA 2RK5A 5FXDA 2VFVA 1E8GA 4BC9A 2QKNA 5FXEA 1W1SA 4HG0A 2Q85A 3AN1A 3NRZB 2QPMA 2AXRA 1N5XA 2OAIA 5I1VA 5G5GB 1W1RA 2WDWA 2Y4GA 1E8FA 1E8HA 1W1LA 5HMRA 3AM9A 1WVEA 4OALA 2NQWA 1HSKA 2VFUA 1W1JA 5FXPA 3TSHA 1AHUA 2BVGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P13 A;  1N5W C;  4BBY A;  5AE1 A;  3W8Z A;  5HQX A;  4ML8 A;  4PWB A;  1ZR6 A;  3LLB A;  4BCA A;  3TX1 A;  5ADZ A;  1VAO A;  5AE3 A;  2GQU A;  5D79 A;  3W8X A;  3NVV B;  1WVF A;  3FWA A;  4ZOH B;  1MBB A;  1JRP A;  1N63 C;  1JRO A;  4O95 A;  3I99 A;  2YVS A;  1QLU A;  1ZXI C;  2EXR A;  3VTE A;  4PYT A;  3W8W A;  3AMZ A;  4XLO A;  2W3R A;  3EUB 3;  2R8D A;  1FIQ B;  1FO4 A;  5AE2 A;  3NVZ B;  4PVH A;  1SB3 B;  1AHV A;  4PVJ A;  1DZN A;  3B9J B;  3TSJ A;  1V97 A;  1T3Q C;  2W54 A;  3FW9 A;  2O3G A;  2W55 A;  3S1E A;  1DII A;  3LAE A;  2BVF A;  3D2J A;  3D2H A;  1I19 A;  2VFS A;  3D2D A;  3ETR B;  2VFT A;  4EC3 A;  5FXF A;  1N61 C;  2MBR A;  3C0P A;  1FFU C;  2GQT A;  3PM9 A;  3BW7 A;  2Q4W A;  1DIQ A;  3FW8 A;  3S1D A;  5HHZ A;  3JS8 A;  1VDV A;  1RM6 B;  1F0X A;  1W1M A;  1W1O A;  1WYG A;  4UD8 A;  2VFR A;  4PVK A;  2PLS A;  3S1F A;  2I0K A;  2E3T A;  4PVE A;  1MBT A;  2R2Z A;  1W1Q A;  3NVY B;  4JB1 A;  1N62 C;  2BVH A;  3KJM A;  2P3H A;  3DQ0 A;  4JAY A;  3FW7 A;  1FFV C;  4MLA A;  5G5H B;  1UXY A;  3HRD C;  3S1C A;  4DNS A;  2PLI A;  3SR6 B;  2P4P A;  3DED A;  4PWC A;  1N60 C;  1W1K A;  1E0Y A;  2VAO A;  3NS1 B;  3GSY A;  1AHZ A;  3NVW B;  2W3S A;  4PZF A;  4BC7 A;  1QLT A;  2RK5 A;  5FXD A;  2VFV A;  1E8G A;  4BC9 A;  2QKN A;  5FXE A;  1W1S A;  4HG0 A;  2Q85 A;  3AN1 A;  3NRZ B;  2QPM A;  2AXR A;  1N5X A;  2OAI A;  5G5G B;  1W1R A;  1E8F A;  1E8H A;  1W1L A;  5HMR A;  3AM9 A;  1WVE A;  4OAL A;  2NQW A;  1HSK A;  2VFU A;  1W1J A;  5FXP A;  3TSH A;  1AHU A;  2BVG A; 
#chains in the Genus database with same CATH topology
 2P13 A;  1N5W C;  5K8E A;  4BBY A;  5AE1 A;  3W8Z A;  5HQX A;  4ML8 A;  4PWB A;  1ZR6 A;  3LLB A;  4BCA A;  2UUV A;  3TX1 A;  5ADZ A;  1VAO A;  5AE3 A;  2GQU A;  3EJD B;  5D79 A;  3W8X A;  3NVV B;  2Y3S A;  1WVF A;  3FWA A;  4ZOH B;  1MBB A;  3EJE B;  1JRP A;  1N63 C;  1JRO A;  3PQB A;  5I1W A;  4O95 A;  3I99 A;  2YVS A;  1QLU A;  1ZXI C;  2EXR A;  3VTE A;  4PYT A;  3POP A;  3W8W A;  3AMZ A;  3RJ8 A;  4XLO A;  2W3R A;  3EUB 3;  2R8D A;  1FIQ B;  1FO4 A;  5AE2 A;  3NVZ B;  4PVH A;  1SB3 B;  2Y3R A;  1AHV A;  4PVJ A;  1DZN A;  3B9J B;  3TSJ A;  1V97 A;  2IPI A;  1T3Q C;  2W54 A;  3FW9 A;  5AWV A;  2O3G A;  2W55 A;  3S1E A;  1DII A;  3LAE A;  2BVF A;  3D2J A;  3D2H A;  1I19 A;  2VFS A;  3D2D A;  3EJB B;  2VFT A;  3ETR B;  4EC3 A;  5FXF A;  1N61 C;  2MBR A;  3C0P A;  1FFU C;  2GQT A;  3PM9 A;  3BW7 A;  2Q4W A;  1DIQ A;  3FW8 A;  3S1D A;  5HHZ A;  3JS8 A;  1VDV A;  1RM6 B;  1F0X A;  1W1M A;  1W1O A;  3HSU A;  1WYG A;  4UD8 A;  2VFR A;  4PVK A;  2PLS A;  3S1F A;  2I0K A;  2E3T A;  2UUU A;  4PVE A;  1MBT A;  5L6F A;  2R2Z A;  1W1Q A;  3NVY B;  4JB1 A;  5L6G A;  2Y08 A;  1N62 C;  2BVH A;  3KJM A;  2P3H A;  3DQ0 A;  4JAY A;  3FW7 A;  1FFV C;  4MLA A;  5G5H B;  1UXY A;  3HRD C;  3S1C A;  4DNS A;  2PLI A;  3SR6 B;  2P4P A;  3DED A;  4PWC A;  1N60 C;  1W1K A;  1E0Y A;  2VAO A;  3RJA A;  3NS1 B;  3GSY A;  1AHZ A;  3NVW B;  2W3S A;  4PZF A;  4BC7 A;  1QLT A;  2RK5 A;  5FXD A;  2VFV A;  1E8G A;  4BC9 A;  2QKN A;  5FXE A;  1W1S A;  4HG0 A;  2Q85 A;  3AN1 A;  3NRZ B;  2QPM A;  2AXR A;  1N5X A;  2OAI A;  5I1V A;  5G5G B;  1W1R A;  2WDW A;  2Y4G A;  1E8F A;  1E8H A;  1W1L A;  5HMR A;  3AM9 A;  1WVE A;  4OAL A;  2NQW A;  1HSK A;  2VFU A;  1W1J A;  5FXP A;  3TSH A;  1AHU A;  2BVG A; 
#chains in the Genus database with same CATH homology
 2P13 A;  1N5W C;  5K8E A;  4BBY A;  5AE1 A;  3W8Z A;  5HQX A;  4ML8 A;  4PWB A;  1ZR6 A;  3LLB A;  4BCA A;  2UUV A;  3TX1 A;  5ADZ A;  1VAO A;  5AE3 A;  2GQU A;  5D79 A;  3W8X A;  3NVV B;  2Y3S A;  1WVF A;  3FWA A;  4ZOH B;  1MBB A;  1JRP A;  5I1W A;  1N63 C;  1JRO A;  3PQB A;  4O95 A;  3I99 A;  2YVS A;  1QLU A;  1ZXI C;  2EXR A;  3VTE A;  4PYT A;  3POP A;  3W8W A;  3AMZ A;  3RJ8 A;  4XLO A;  2W3R A;  3EUB 3;  2R8D A;  1FIQ B;  1FO4 A;  5AE2 A;  3NVZ B;  4PVH A;  1SB3 B;  2Y3R A;  1AHV A;  4PVJ A;  1DZN A;  3B9J B;  3TSJ A;  1V97 A;  2IPI A;  1T3Q C;  2W54 A;  3FW9 A;  5AWV A;  2O3G A;  2W55 A;  3S1E A;  1DII A;  3LAE A;  2BVF A;  3D2J A;  3D2H A;  1I19 A;  2VFS A;  3D2D A;  3ETR B;  2VFT A;  4EC3 A;  5FXF A;  1N61 C;  2MBR A;  3C0P A;  1FFU C;  2GQT A;  3PM9 A;  3BW7 A;  2Q4W A;  1DIQ A;  3FW8 A;  3S1D A;  5HHZ A;  3JS8 A;  1VDV A;  1RM6 B;  1F0X A;  1W1M A;  1W1O A;  3HSU A;  1WYG A;  4UD8 A;  2VFR A;  4PVK A;  2PLS A;  3S1F A;  2I0K A;  2E3T A;  2UUU A;  4PVE A;  1MBT A;  5L6F A;  2R2Z A;  1W1Q A;  3NVY B;  4JB1 A;  5L6G A;  2Y08 A;  1N62 C;  2BVH A;  3KJM A;  2P3H A;  3DQ0 A;  4JAY A;  3FW7 A;  1FFV C;  4MLA A;  5G5H B;  1UXY A;  3HRD C;  3S1C A;  4DNS A;  2PLI A;  3SR6 B;  2P4P A;  3DED A;  4PWC A;  1N60 C;  1W1K A;  1E0Y A;  2VAO A;  3RJA A;  3NS1 B;  3GSY A;  1AHZ A;  3NVW B;  2W3S A;  4PZF A;  4BC7 A;  1QLT A;  2RK5 A;  5FXD A;  2VFV A;  1E8G A;  4BC9 A;  2QKN A;  5FXE A;  1W1S A;  4HG0 A;  2Q85 A;  3AN1 A;  3NRZ B;  2QPM A;  2AXR A;  1N5X A;  2OAI A;  5I1V A;  5G5G B;  1W1R A;  2WDW A;  2Y4G A;  1E8F A;  1E8H A;  1W1L A;  5HMR A;  3AM9 A;  1WVE A;  4OAL A;  2NQW A;  1HSK A;  2VFU A;  1W1J A;  5FXP A;  3TSH A;  1AHU A;  2BVG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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