2I0KA

Cholesterol oxidase from brevibacterium sterolicum- his121ala mutant
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
556
structure length
536
Chain Sequence
APLPTPPNFPNDIALFQQAYQNWSKEIMLDATWVCSPKTPQDVVRLANWAHEHDYKIRPRGAMAGWTPLTVEKGANVEKVILADTMTHLNGITVNTGGPVATVTAGAGASIEAIVTELQKHDLGWANLPAPGVLSIGGALAVNAHGAALPAVGQTTLPGHTYGSLSNLVTELTAVVWNGTTYALETYQRNDPRITPLLTNLGRCFLTSVTMQAGPNFRQRCQSYTDIPWRELFAPKGADGRTFEKFVAESGGAEAIWYPFTEKPWMKVWTVSGKPPQAREVSGPYNYIFSDNLPEPITDMIGAINAGNPGIAPLFGPAMYEITKLGLAATNANDIWGWSKDVQFYIKATTLRLTEGGGAVVTSRANIATVINDFTEWFHERIEFYRAKGEFPLNGPVEIRCCGLDQAADVKVPSVGPPTISATRPRPDHPDWDVAIWLNVLGVPGTPGMFEFYREMEQWMRSHYNNDDATFRPEWSKGWAFGPDPYTDNDIVTNKMRATYIEGVPTTENWDTARARYNQIDPHRVFTNGFMDKLLP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.
pubmed doi rcsb
source organism Brevibacterium sterolicum
molecule tags Oxidoreductase
molecule keywords Oxidoreductase
total genus 175
structure length 536
sequence length 556
ec nomenclature ec 1.1.3.6: Cholesterol oxidase.
pdb deposition date 2006-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF09129 Chol_subst-bind Cholesterol oxidase, substrate-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2i0kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2i0kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2i0kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2i0kA03
2VFUA 1AHZA 3EUB3 1N5XA 4BCAA 1N63C 1FIQB 2AXRA 2OAIA 4PVJA 2RK5A 2Q4WA 3S1DA 5HHZA 2P4PA 3GSYA 1AHVA 2W55A 4BC7A 1VDVA 2W3SA 4PVHA 3NVYB 5FXEA 1E8HA 5G5GB 5FXFA 1AHUA 1N5WC 1DIQA 3S1FA 4DNSA 3AN1A 1RM6B 3BW7A 2MBRA 1W1QA 5HQXA 1E0YA 3D2DA 5ADZA 3FW8A 1JROA 3NVWB 1WVEA 2E3TA 3AMZA 2P3HA 3S1CA 1V97A 1W1JA 5FXPA 3AM9A 1W1RA 1W1KA 2GQTA 1DZNA 2VAOA 3NS1B 1FO4A 1ZXIC 4PVEA 2QKNA 1JRPA 3D2JA 4ML8A 1SB3B 3LLBA 4BC9A 3FW9A 1ZR6A 2BVFA 1HSKA 3NRZB 3W8ZA 1W1OA 1E8GA 2VFSA 2BVHA 2Q85A 3DEDA 3D2HA 2PLSA 2VFTA 4MLAA 2W54A 2VFVA 1T3QC 3NVZB 4JB1A 2W3RA 5AE2A 4PYTA 1I19A 1E8FA 3SR6B 4EC3A 4PWBA 1W1SA 2I0KA 2EXRA 3LAEA 2VFRA 3W8WA 1N60C 3TSHA 5AE1A 2QPMA 2R2ZA 2BVGA 4HG0A 2O3GA 5FXDA 3C0PA 3W8XA 3ETRB 1WYGA 3VTEA 2P13A 1FFVC 3TX1A 3B9JB 1QLTA 4PWCA 1MBTA 1UXYA 5G5HB 1W1MA 2GQUA 2PLIA 1W1LA 1WVFA 3KJMA 3FW7A 1N62C 3I99A 4OALA 3PM9A 3NVVB 1DIIA 1N61C 3FWAA 3S1EA 4O95A 4PVKA 5AE3A 5D79A 3JS8A 4JAYA 1F0XA 1QLUA 1MBBA 4PZFA 4ZOHB 2YVSA 3TSJA 1FFUC 3DQ0A 2NQWA 4BBYA 5HMRA 4XLOA 1VAOA 3HRDC 4UD8A 2R8DA
chains in the Genus database with same CATH superfamily
2VFUA 1AHZA 2WDWA 3EUB3 2UUUA 1N5XA 4BCAA 1N63C 1FIQB 2AXRA 2OAIA 4PVJA 2RK5A 2Q4WA 3S1DA 5HHZA 2P4PA 3GSYA 1AHVA 2W55A 5L6GA 3HSUA 4BC7A 1VDVA 2W3SA 4PVHA 3NVYB 5FXEA 1E8HA 2Y3RA 5G5GB 5FXFA 1AHUA 1N5WC 1DIQA 3S1FA 4DNSA 3AN1A 1RM6B 3BW7A 2MBRA 1W1QA 5HQXA 1E0YA 3D2DA 5ADZA 3FW8A 2Y3SA 5I1VA 1JROA 3NVWB 1WVEA 2E3TA 3AMZA 2P3HA 3S1CA 1V97A 1W1JA 5FXPA 3AM9A 1W1RA 1W1KA 2GQTA 1DZNA 2VAOA 3NS1B 1FO4A 1ZXIC 3EJBB 4PVEA 2QKNA 1JRPA 5L6FA 3D2JA 4ML8A 1SB3B 3RJAA 3LLBA 3EJDB 4BC9A 3FW9A 1ZR6A 2BVFA 1HSKA 3NRZB 3W8ZA 1W1OA 1E8GA 2VFSA 2BVHA 2Q85A 2UUVA 3D2HA 2PLSA 2Y4GA 2VFTA 4MLAA 2W54A 2VFVA 1T3QC 3NVZB 4JB1A 2W3RA 5AE2A 4PYTA 1I19A 1E8FA 3SR6B 5I1WA 4EC3A 4PWBA 1W1SA 2I0KA 2EXRA 3LAEA 2VFRA 3RJ8A 3W8WA 1N60C 3TSHA 5AE1A 2QPMA 3DEDA 2R2ZA 3POPA 2Y08A 2BVGA 4HG0A 5AWVA 2O3GA 5FXDA 3C0PA 3W8XA 3ETRB 1WYGA 3VTEA 2P13A 1FFVC 3TX1A 3B9JB 1QLTA 4PWCA 1MBTA 1UXYA 5G5HB 1W1MA 3EJEB 2GQUA 2PLIA 1W1LA 1WVFA 3KJMA 3FW7A 1N62C 3I99A 4OALA 3PM9A 3NVVB 1DIIA 1N61C 3FWAA 3S1EA 4O95A 4PVKA 5AE3A 5D79A 3JS8A 4JAYA 1F0XA 3PQBA 1QLUA 1MBBA 4PZFA 4ZOHB 5K8EA 2YVSA 3TSJA 1FFUC 3DQ0A 2NQWA 4BBYA 5HMRA 4XLOA 1VAOA 3HRDC 2IPIA 4UD8A 2R8DA
chains in the Genus database with same CATH topology
2VFUA 1AHZA 2WDWA 3EUB3 2UUUA 1N5XA 4BCAA 1N63C 1FIQB 2AXRA 2OAIA 4PVJA 2RK5A 2Q4WA 3S1DA 5HHZA 2P4PA 3GSYA 1AHVA 2W55A 5L6GA 3HSUA 4BC7A 1VDVA 2W3SA 4PVHA 3NVYB 5FXEA 1E8HA 2Y3RA 5G5GB 5FXFA 1AHUA 1N5WC 1DIQA 3S1FA 4DNSA 3AN1A 1RM6B 3BW7A 2MBRA 1W1QA 5HQXA 1E0YA 3D2DA 5ADZA 3FW8A 2Y3SA 5I1VA 1JROA 3NVWB 1WVEA 2E3TA 3AMZA 2P3HA 3S1CA 1V97A 1W1JA 5FXPA 3AM9A 1W1RA 1W1KA 2GQTA 1DZNA 2VAOA 3NS1B 1FO4A 1ZXIC 4PVEA 2QKNA 1JRPA 5L6FA 3D2JA 4ML8A 1SB3B 3RJAA 3LLBA 4BC9A 3FW9A 1ZR6A 2BVFA 1HSKA 3NRZB 3W8ZA 1W1OA 1E8GA 2VFSA 2BVHA 2Q85A 2UUVA 3D2HA 2PLSA 2Y4GA 2VFTA 4MLAA 2W54A 2VFVA 1T3QC 3NVZB 4JB1A 2W3RA 5AE2A 4PYTA 1I19A 1E8FA 3SR6B 5I1WA 4EC3A 4PWBA 1W1SA 2I0KA 2EXRA 3LAEA 2VFRA 3RJ8A 3W8WA 1N60C 3TSHA 5AE1A 2QPMA 3DEDA 2R2ZA 3POPA 2Y08A 2BVGA 4HG0A 5AWVA 2O3GA 5FXDA 3C0PA 3W8XA 3ETRB 1WYGA 3VTEA 2P13A 1FFVC 3TX1A 3B9JB 1QLTA 4PWCA 1MBTA 1UXYA 5G5HB 1W1MA 2GQUA 2PLIA 1W1LA 1WVFA 3KJMA 3FW7A 1N62C 3I99A 4OALA 3PM9A 3NVVB 1DIIA 1N61C 3FWAA 3S1EA 4O95A 4PVKA 5AE3A 5D79A 3JS8A 4JAYA 1F0XA 3PQBA 1QLUA 1MBBA 4PZFA 4ZOHB 5K8EA 2YVSA 3TSJA 1FFUC 3DQ0A 2NQWA 4BBYA 5HMRA 4XLOA 1VAOA 3HRDC 2IPIA 4UD8A 2R8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VFU A;  1AHZ A;  3EUB 3;  1N5X A;  4BCA A;  1N63 C;  1FIQ B;  2AXR A;  2OAI A;  4PVJ A;  2RK5 A;  2Q4W A;  3S1D A;  5HHZ A;  2P4P A;  3GSY A;  1AHV A;  2W55 A;  4BC7 A;  1VDV A;  2W3S A;  4PVH A;  3NVY B;  5FXE A;  1E8H A;  5G5G B;  5FXF A;  1AHU A;  1N5W C;  1DIQ A;  3S1F A;  4DNS A;  3AN1 A;  1RM6 B;  3BW7 A;  2MBR A;  1W1Q A;  5HQX A;  1E0Y A;  3D2D A;  5ADZ A;  3FW8 A;  1JRO A;  3NVW B;  1WVE A;  2E3T A;  3AMZ A;  2P3H A;  3S1C A;  1V97 A;  1W1J A;  5FXP A;  3AM9 A;  1W1R A;  1W1K A;  2GQT A;  1DZN A;  2VAO A;  3NS1 B;  1FO4 A;  1ZXI C;  4PVE A;  2QKN A;  1JRP A;  3D2J A;  4ML8 A;  1SB3 B;  3LLB A;  4BC9 A;  3FW9 A;  1ZR6 A;  2BVF A;  1HSK A;  3NRZ B;  3W8Z A;  1W1O A;  1E8G A;  2VFS A;  2BVH A;  2Q85 A;  3DED A;  3D2H A;  2PLS A;  2VFT A;  4MLA A;  2W54 A;  2VFV A;  1T3Q C;  3NVZ B;  4JB1 A;  2W3R A;  5AE2 A;  4PYT A;  1I19 A;  1E8F A;  3SR6 B;  4EC3 A;  4PWB A;  1W1S A;  2I0K A;  2EXR A;  3LAE A;  2VFR A;  3W8W A;  1N60 C;  3TSH A;  5AE1 A;  2QPM A;  2R2Z A;  2BVG A;  4HG0 A;  2O3G A;  5FXD A;  3C0P A;  3W8X A;  3ETR B;  1WYG A;  3VTE A;  2P13 A;  1FFV C;  3TX1 A;  3B9J B;  1QLT A;  4PWC A;  1MBT A;  1UXY A;  5G5H B;  1W1M A;  2GQU A;  2PLI A;  1W1L A;  1WVF A;  3KJM A;  3FW7 A;  1N62 C;  3I99 A;  4OAL A;  3PM9 A;  3NVV B;  1DII A;  1N61 C;  3FWA A;  3S1E A;  4O95 A;  4PVK A;  5AE3 A;  5D79 A;  3JS8 A;  4JAY A;  1F0X A;  1QLU A;  1MBB A;  4PZF A;  4ZOH B;  2YVS A;  3TSJ A;  1FFU C;  3DQ0 A;  2NQW A;  4BBY A;  5HMR A;  4XLO A;  1VAO A;  3HRD C;  4UD8 A;  2R8D A; 
#chains in the Genus database with same CATH topology
 2VFU A;  1AHZ A;  2WDW A;  3EUB 3;  2UUU A;  1N5X A;  4BCA A;  1N63 C;  1FIQ B;  2AXR A;  2OAI A;  4PVJ A;  2RK5 A;  2Q4W A;  3S1D A;  5HHZ A;  2P4P A;  3GSY A;  1AHV A;  2W55 A;  5L6G A;  3HSU A;  4BC7 A;  1VDV A;  2W3S A;  4PVH A;  3NVY B;  5FXE A;  1E8H A;  2Y3R A;  5G5G B;  5FXF A;  1AHU A;  1N5W C;  1DIQ A;  3S1F A;  4DNS A;  3AN1 A;  1RM6 B;  3BW7 A;  2MBR A;  1W1Q A;  5HQX A;  1E0Y A;  3D2D A;  5ADZ A;  3FW8 A;  2Y3S A;  5I1V A;  1JRO A;  3NVW B;  1WVE A;  2E3T A;  3AMZ A;  2P3H A;  3S1C A;  1V97 A;  1W1J A;  5FXP A;  3AM9 A;  1W1R A;  1W1K A;  2GQT A;  1DZN A;  2VAO A;  3NS1 B;  1FO4 A;  1ZXI C;  3EJB B;  4PVE A;  2QKN A;  1JRP A;  5L6F A;  3D2J A;  4ML8 A;  1SB3 B;  3RJA A;  3LLB A;  3EJD B;  4BC9 A;  3FW9 A;  1ZR6 A;  2BVF A;  1HSK A;  3NRZ B;  3W8Z A;  1W1O A;  1E8G A;  2VFS A;  2BVH A;  2Q85 A;  2UUV A;  3D2H A;  2PLS A;  2Y4G A;  2VFT A;  4MLA A;  2W54 A;  2VFV A;  1T3Q C;  3NVZ B;  4JB1 A;  2W3R A;  5AE2 A;  4PYT A;  1I19 A;  1E8F A;  3SR6 B;  5I1W A;  4EC3 A;  4PWB A;  1W1S A;  2I0K A;  2EXR A;  3LAE A;  2VFR A;  3RJ8 A;  3W8W A;  1N60 C;  3TSH A;  5AE1 A;  2QPM A;  3DED A;  2R2Z A;  3POP A;  2Y08 A;  2BVG A;  4HG0 A;  5AWV A;  2O3G A;  5FXD A;  3C0P A;  3W8X A;  3ETR B;  1WYG A;  3VTE A;  2P13 A;  1FFV C;  3TX1 A;  3B9J B;  1QLT A;  4PWC A;  1MBT A;  1UXY A;  5G5H B;  1W1M A;  3EJE B;  2GQU A;  2PLI A;  1W1L A;  1WVF A;  3KJM A;  3FW7 A;  1N62 C;  3I99 A;  4OAL A;  3PM9 A;  3NVV B;  1DII A;  1N61 C;  3FWA A;  3S1E A;  4O95 A;  4PVK A;  5AE3 A;  5D79 A;  3JS8 A;  4JAY A;  1F0X A;  3PQB A;  1QLU A;  1MBB A;  4PZF A;  4ZOH B;  5K8E A;  2YVS A;  3TSJ A;  1FFU C;  3DQ0 A;  2NQW A;  4BBY A;  5HMR A;  4XLO A;  1VAO A;  3HRD C;  2IPI A;  4UD8 A;  2R8D A; 
#chains in the Genus database with same CATH homology
 2VFU A;  1AHZ A;  2WDW A;  3EUB 3;  2UUU A;  1N5X A;  4BCA A;  1N63 C;  1FIQ B;  2AXR A;  2OAI A;  4PVJ A;  2RK5 A;  2Q4W A;  3S1D A;  5HHZ A;  2P4P A;  3GSY A;  1AHV A;  2W55 A;  5L6G A;  3HSU A;  4BC7 A;  1VDV A;  2W3S A;  4PVH A;  3NVY B;  5FXE A;  1E8H A;  2Y3R A;  5G5G B;  5FXF A;  1AHU A;  1N5W C;  1DIQ A;  3S1F A;  4DNS A;  3AN1 A;  1RM6 B;  3BW7 A;  2MBR A;  1W1Q A;  5HQX A;  1E0Y A;  3D2D A;  5ADZ A;  3FW8 A;  2Y3S A;  5I1V A;  1JRO A;  3NVW B;  1WVE A;  2E3T A;  3AMZ A;  2P3H A;  3S1C A;  1V97 A;  1W1J A;  5FXP A;  3AM9 A;  1W1R A;  1W1K A;  2GQT A;  1DZN A;  2VAO A;  3NS1 B;  1FO4 A;  1ZXI C;  4PVE A;  2QKN A;  1JRP A;  5L6F A;  3D2J A;  4ML8 A;  1SB3 B;  3RJA A;  3LLB A;  4BC9 A;  3FW9 A;  1ZR6 A;  2BVF A;  1HSK A;  3NRZ B;  3W8Z A;  1W1O A;  1E8G A;  2VFS A;  2BVH A;  2Q85 A;  2UUV A;  3D2H A;  2PLS A;  2Y4G A;  2VFT A;  4MLA A;  2W54 A;  2VFV A;  1T3Q C;  3NVZ B;  4JB1 A;  2W3R A;  5AE2 A;  4PYT A;  1I19 A;  1E8F A;  3SR6 B;  5I1W A;  4EC3 A;  4PWB A;  1W1S A;  2I0K A;  2EXR A;  3LAE A;  2VFR A;  3RJ8 A;  3W8W A;  1N60 C;  3TSH A;  5AE1 A;  2QPM A;  3DED A;  2R2Z A;  3POP A;  2Y08 A;  2BVG A;  4HG0 A;  5AWV A;  2O3G A;  5FXD A;  3C0P A;  3W8X A;  3ETR B;  1WYG A;  3VTE A;  2P13 A;  1FFV C;  3TX1 A;  3B9J B;  1QLT A;  4PWC A;  1MBT A;  1UXY A;  5G5H B;  1W1M A;  2GQU A;  2PLI A;  1W1L A;  1WVF A;  3KJM A;  3FW7 A;  1N62 C;  3I99 A;  4OAL A;  3PM9 A;  3NVV B;  1DII A;  1N61 C;  3FWA A;  3S1E A;  4O95 A;  4PVK A;  5AE3 A;  5D79 A;  3JS8 A;  4JAY A;  1F0X A;  3PQB A;  1QLU A;  1MBB A;  4PZF A;  4ZOH B;  5K8E A;  2YVS A;  3TSJ A;  1FFU C;  3DQ0 A;  2NQW A;  4BBY A;  5HMR A;  4XLO A;  1VAO A;  3HRD C;  2IPI A;  4UD8 A;  2R8D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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