2I0KA

Cholesterol oxidase from brevibacterium sterolicum- his121ala mutant
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
556
structure length
536
Chain Sequence
b'APLPTPPNFPNDIALFQQAYQNWSKEIMLDATWVCSPKTPQDVVRLANWAHEHDYKIRPRGAMAGWTPLTVEKGANVEKVILADTMTHLNGITVNTGGPVATVTAGAGASIEAIVTELQKHDLGWANLPAPGVLSIGGALAVNAHGAALPAVGQTTLPGHTYGSLSNLVTELTAVVWNGTTYALETYQRNDPRITPLLTNLGRCFLTSVTMQAGPNFRQRCQSYTDIPWRELFAPKGADGRTFEKFVAESGGAEAIWYPFTEKPWMKVWTVSGKPPQAREVSGPYNYIFSDNLPEPITDMIGAINAGNPGIAPLFGPAMYEITKLGLAATNANDIWGWSKDVQFYIKATTLRLTEGGGAVVTSRANIATVINDFTEWFHERIEFYRAKGEFPLNGPVEIRCCGLDQAADVKVPSVGPPTISATRPRPDHPDWDVAIWLNVLGVPGTPGMFEFYREMEQWMRSHYNNDDATFRPEWSKGWAFGPDPYTDNDIVTNKMRATYIEGVPTTENWDTARARYNQIDPHRVFTNGFMDKLLP'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Oxidoreductase
publication title Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.
pubmed doi rcsb
source organism Brevibacterium sterolicum
molecule tags Oxidoreductase
total genus 175
structure length 536
sequence length 556
ec nomenclature ec 1.1.3.6: Cholesterol oxidase.
pdb deposition date 2006-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF09129 Chol_subst-bind Cholesterol oxidase, substrate-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2i0kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2i0kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2i0kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2i0kA03
1W1SA 3S1CA 2BVFA 1FO4A 1JRPA 5FXFA 2VFSA 1VDVA 1FIQB 1I19A 5AE3A 3D2DA 4EC3A 3HRDC 2PLIA 3AMZA 2MBRA 2W3RA 3NRZB 3S1DA 3TSHA 2W55A 2BVHA 1SB3B 4O95A 3D2HA 1DZNA 2W54A 3S1EA 2QPMA 5AE1A 3SR6B 1AHZA 1N5WC 4PVJA 1FFVC 1RM6B 2YVSA 4BC9A 4HG0A 4PVHA 1E0YA 1E8GA 2I0KA 2Q4WA 2BVGA 4PZFA 2AXRA 3C0PA 3DEDA 1VAOA 2VFTA 3FWAA 1DIQA 2VAOA 1W1OA 3FW9A 3ETRB 3LAEA 3TSJA 1E8HA 3PM9A 1QLTA 3TX1A 4PYTA 5HHZA 3I99A 3D2JA 4PWBA 1N62C 4UD8A 4JB1A 3NVVB 4ML8A 1FFUC 1W1QA 2R2ZA 2VFVA 3S1FA 2O3GA 3W8ZA 4BBYA 2GQUA 4PVEA 3W8XA 2OAIA 4ZOHB 1W1KA 2PLSA 4BC7A 1AHVA 1N5XA 4PWCA 2QKNA 1V97A 3JS8A 2P13A 3BW7A 1N63C 2R8DA 2W3SA 2RK5A 5HMRA 3AM9A 3LLBA 1HSKA 3EUB3 3FW8A 3NS1B 1MBBA 1F0XA 2GQTA 1W1LA 1N60C 1QLUA 5HQXA 5G5GB 5G5HB 1JROA 5D79A 5FXEA 5FXDA 1UXYA 2E3TA 3VTEA 2P3HA 3KJMA 2VFUA 1T3QC 2P4PA 3DQ0A 1W1RA 4PVKA 2VFRA 4JAYA 4OALA 1E8FA 2NQWA 1WVEA 5FXPA 3AN1A 3NVYB 3NVZB 1WVFA 5AE2A 3W8WA 4MLAA 3B9JB 4XLOA 1WYGA 1DIIA 2Q85A 3GSYA 3NVWB 1ZXIC 1W1JA 1MBTA 2EXRA 1AHUA 1W1MA 1ZR6A 5ADZA 4DNSA 1N61C 3FW7A 4BCAA
chains in the Genus database with same CATH superfamily
1W1SA 3S1CA 2BVFA 1FO4A 1JRPA 3POPA 2WDWA 5FXFA 2VFSA 1VDVA 2UUVA 1FIQB 1I19A 5AE3A 3D2DA 4EC3A 3HRDC 2PLIA 3AMZA 2MBRA 2W3RA 3NRZB 3S1DA 3TSHA 2W55A 2BVHA 1SB3B 4O95A 3D2HA 1DZNA 2W54A 5K8EA 3S1EA 2QPMA 5AE1A 3SR6B 1AHZA 1N5WC 4PVJA 1FFVC 1RM6B 2YVSA 4BC9A 4HG0A 4PVHA 1E0YA 2Y3SA 1E8GA 2I0KA 2Q4WA 2BVGA 4PZFA 2AXRA 3C0PA 3DEDA 3HSUA 1VAOA 2VFTA 3FWAA 1DIQA 3PQBA 2VAOA 1W1OA 3FW9A 3ETRB 3LAEA 3TSJA 1E8HA 3PM9A 1QLTA 3TX1A 4PYTA 5HHZA 3I99A 3RJAA 3D2JA 4PWBA 5L6GA 1N62C 4UD8A 4JB1A 3NVVB 4ML8A 1FFUC 1W1QA 3EJEB 2R2ZA 2VFVA 2Y4GA 3S1FA 2O3GA 2Y08A 3W8ZA 4BBYA 2GQUA 4PVEA 3W8XA 2OAIA 4ZOHB 1W1KA 5L6FA 3EJBB 2PLSA 4BC7A 1AHVA 1N5XA 4PWCA 2QKNA 1V97A 3JS8A 2P13A 3BW7A 2Y3RA 5I1WA 1N63C 2R8DA 2UUUA 5AWVA 3RJ8A 2W3SA 2RK5A 5HMRA 3AM9A 3LLBA 1HSKA 3EUB3 3FW8A 3NS1B 5I1VA 1MBBA 1F0XA 2GQTA 1W1LA 1N60C 1QLUA 5HQXA 5G5GB 5G5HB 1JROA 5D79A 5FXEA 5FXDA 1UXYA 2E3TA 3VTEA 2P3HA 3KJMA 2VFUA 1T3QC 2P4PA 3DQ0A 1W1RA 4PVKA 2VFRA 4JAYA 4OALA 1E8FA 2NQWA 1WVEA 5FXPA 3AN1A 3NVYB 3NVZB 2IPIA 1WVFA 5AE2A 3W8WA 4MLAA 3B9JB 4XLOA 1WYGA 1DIIA 2Q85A 3GSYA 3NVWB 1ZXIC 1W1JA 1MBTA 2EXRA 1AHUA 1W1MA 1ZR6A 5ADZA 4DNSA 3EJDB 1N61C 3FW7A 4BCAA
chains in the Genus database with same CATH topology
1W1SA 3S1CA 2BVFA 1FO4A 1JRPA 3POPA 2WDWA 5FXFA 2VFSA 1VDVA 2UUVA 1FIQB 1I19A 5AE3A 3D2DA 4EC3A 3HRDC 2PLIA 3AMZA 2MBRA 2W3RA 3NRZB 3S1DA 3TSHA 2W55A 2BVHA 1SB3B 4O95A 3D2HA 1DZNA 2W54A 5K8EA 3S1EA 2QPMA 5AE1A 3SR6B 1AHZA 1N5WC 4PVJA 1FFVC 1RM6B 2YVSA 4BC9A 4HG0A 4PVHA 1E0YA 2Y3SA 1E8GA 2I0KA 2Q4WA 2BVGA 4PZFA 2AXRA 3C0PA 3DEDA 3HSUA 1VAOA 2VFTA 3FWAA 1DIQA 3PQBA 2VAOA 1W1OA 3FW9A 3ETRB 3LAEA 3TSJA 1E8HA 3PM9A 1QLTA 3TX1A 4PYTA 5HHZA 3I99A 3RJAA 3D2JA 4PWBA 5L6GA 1N62C 4UD8A 4JB1A 3NVVB 4ML8A 1FFUC 1W1QA 2R2ZA 2VFVA 2Y4GA 3S1FA 2O3GA 2Y08A 3W8ZA 4BBYA 2GQUA 4PVEA 3W8XA 2OAIA 4ZOHB 1W1KA 5L6FA 2PLSA 4BC7A 1AHVA 1N5XA 4PWCA 2QKNA 1V97A 3JS8A 2P13A 3BW7A 2Y3RA 5I1WA 1N63C 2R8DA 2UUUA 5AWVA 3RJ8A 2W3SA 2RK5A 5HMRA 3AM9A 3LLBA 1HSKA 3EUB3 3FW8A 3NS1B 5I1VA 1MBBA 1F0XA 2GQTA 1W1LA 1N60C 1QLUA 5HQXA 5G5GB 5G5HB 1JROA 5D79A 5FXEA 5FXDA 1UXYA 2E3TA 3VTEA 2P3HA 3KJMA 2VFUA 1T3QC 2P4PA 3DQ0A 1W1RA 4PVKA 2VFRA 4JAYA 4OALA 1E8FA 2NQWA 1WVEA 5FXPA 3AN1A 2IPIA 3NVZB 3NVYB 1WVFA 5AE2A 3W8WA 4MLAA 3B9JB 4XLOA 1WYGA 1DIIA 2Q85A 3GSYA 3NVWB 1ZXIC 1W1JA 1MBTA 2EXRA 1AHUA 1W1MA 1ZR6A 5ADZA 4DNSA 1N61C 3FW7A 4BCAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W1S A;  3S1C A;  2BVF A;  1FO4 A;  1JRP A;  5FXF A;  2VFS A;  1VDV A;  1FIQ B;  1I19 A;  5AE3 A;  3D2D A;  4EC3 A;  3HRD C;  2PLI A;  3AMZ A;  2MBR A;  2W3R A;  3NRZ B;  3S1D A;  3TSH A;  2W55 A;  2BVH A;  1SB3 B;  4O95 A;  3D2H A;  1DZN A;  2W54 A;  3S1E A;  2QPM A;  5AE1 A;  3SR6 B;  1AHZ A;  1N5W C;  4PVJ A;  1FFV C;  1RM6 B;  2YVS A;  4BC9 A;  4HG0 A;  4PVH A;  1E0Y A;  1E8G A;  2I0K A;  2Q4W A;  2BVG A;  4PZF A;  2AXR A;  3C0P A;  3DED A;  1VAO A;  2VFT A;  3FWA A;  1DIQ A;  2VAO A;  1W1O A;  3FW9 A;  3ETR B;  3LAE A;  3TSJ A;  1E8H A;  3PM9 A;  1QLT A;  3TX1 A;  4PYT A;  5HHZ A;  3I99 A;  3D2J A;  4PWB A;  1N62 C;  4UD8 A;  4JB1 A;  3NVV B;  4ML8 A;  1FFU C;  1W1Q A;  2R2Z A;  2VFV A;  3S1F A;  2O3G A;  3W8Z A;  4BBY A;  2GQU A;  4PVE A;  3W8X A;  2OAI A;  4ZOH B;  1W1K A;  2PLS A;  4BC7 A;  1AHV A;  1N5X A;  4PWC A;  2QKN A;  1V97 A;  3JS8 A;  2P13 A;  3BW7 A;  1N63 C;  2R8D A;  2W3S A;  2RK5 A;  5HMR A;  3AM9 A;  3LLB A;  1HSK A;  3EUB 3;  3FW8 A;  3NS1 B;  1MBB A;  1F0X A;  2GQT A;  1W1L A;  1N60 C;  1QLU A;  5HQX A;  5G5G B;  5G5H B;  1JRO A;  5D79 A;  5FXE A;  5FXD A;  1UXY A;  2E3T A;  3VTE A;  2P3H A;  3KJM A;  2VFU A;  1T3Q C;  2P4P A;  3DQ0 A;  1W1R A;  4PVK A;  2VFR A;  4JAY A;  4OAL A;  1E8F A;  2NQW A;  1WVE A;  5FXP A;  3AN1 A;  3NVY B;  3NVZ B;  1WVF A;  5AE2 A;  3W8W A;  4MLA A;  3B9J B;  4XLO A;  1WYG A;  1DII A;  2Q85 A;  3GSY A;  3NVW B;  1ZXI C;  1W1J A;  1MBT A;  2EXR A;  1AHU A;  1W1M A;  1ZR6 A;  5ADZ A;  4DNS A;  1N61 C;  3FW7 A;  4BCA A; 
#chains in the Genus database with same CATH topology
 1W1S A;  3S1C A;  2BVF A;  1FO4 A;  1JRP A;  3POP A;  2WDW A;  5FXF A;  2VFS A;  1VDV A;  2UUV A;  1FIQ B;  1I19 A;  5AE3 A;  3D2D A;  4EC3 A;  3HRD C;  2PLI A;  3AMZ A;  2MBR A;  2W3R A;  3NRZ B;  3S1D A;  3TSH A;  2W55 A;  2BVH A;  1SB3 B;  4O95 A;  3D2H A;  1DZN A;  2W54 A;  5K8E A;  3S1E A;  2QPM A;  5AE1 A;  3SR6 B;  1AHZ A;  1N5W C;  4PVJ A;  1FFV C;  1RM6 B;  2YVS A;  4BC9 A;  4HG0 A;  4PVH A;  1E0Y A;  2Y3S A;  1E8G A;  2I0K A;  2Q4W A;  2BVG A;  4PZF A;  2AXR A;  3C0P A;  3DED A;  3HSU A;  1VAO A;  2VFT A;  3FWA A;  1DIQ A;  3PQB A;  2VAO A;  1W1O A;  3FW9 A;  3ETR B;  3LAE A;  3TSJ A;  1E8H A;  3PM9 A;  1QLT A;  3TX1 A;  4PYT A;  5HHZ A;  3I99 A;  3RJA A;  3D2J A;  4PWB A;  5L6G A;  1N62 C;  4UD8 A;  4JB1 A;  3NVV B;  4ML8 A;  1FFU C;  1W1Q A;  3EJE B;  2R2Z A;  2VFV A;  2Y4G A;  3S1F A;  2O3G A;  2Y08 A;  3W8Z A;  4BBY A;  2GQU A;  4PVE A;  3W8X A;  2OAI A;  4ZOH B;  1W1K A;  5L6F A;  3EJB B;  2PLS A;  4BC7 A;  1AHV A;  1N5X A;  4PWC A;  2QKN A;  1V97 A;  3JS8 A;  2P13 A;  3BW7 A;  2Y3R A;  5I1W A;  1N63 C;  2R8D A;  2UUU A;  5AWV A;  3RJ8 A;  2W3S A;  2RK5 A;  5HMR A;  3AM9 A;  3LLB A;  1HSK A;  3EUB 3;  3FW8 A;  3NS1 B;  5I1V A;  1MBB A;  1F0X A;  2GQT A;  1W1L A;  1N60 C;  1QLU A;  5HQX A;  5G5G B;  5G5H B;  1JRO A;  5D79 A;  5FXE A;  5FXD A;  1UXY A;  2E3T A;  3VTE A;  2P3H A;  3KJM A;  2VFU A;  1T3Q C;  2P4P A;  3DQ0 A;  1W1R A;  4PVK A;  2VFR A;  4JAY A;  4OAL A;  1E8F A;  2NQW A;  1WVE A;  5FXP A;  3AN1 A;  3NVY B;  3NVZ B;  2IPI A;  1WVF A;  5AE2 A;  3W8W A;  4MLA A;  3B9J B;  4XLO A;  1WYG A;  1DII A;  2Q85 A;  3GSY A;  3NVW B;  1ZXI C;  1W1J A;  1MBT A;  2EXR A;  1AHU A;  1W1M A;  1ZR6 A;  5ADZ A;  4DNS A;  3EJD B;  1N61 C;  3FW7 A;  4BCA A; 
#chains in the Genus database with same CATH homology
 1W1S A;  3S1C A;  2BVF A;  1FO4 A;  1JRP A;  3POP A;  2WDW A;  5FXF A;  2VFS A;  1VDV A;  2UUV A;  1FIQ B;  1I19 A;  5AE3 A;  3D2D A;  4EC3 A;  3HRD C;  2PLI A;  3AMZ A;  2MBR A;  2W3R A;  3NRZ B;  3S1D A;  3TSH A;  2W55 A;  2BVH A;  1SB3 B;  4O95 A;  3D2H A;  1DZN A;  2W54 A;  5K8E A;  3S1E A;  2QPM A;  5AE1 A;  3SR6 B;  1AHZ A;  1N5W C;  4PVJ A;  1FFV C;  1RM6 B;  2YVS A;  4BC9 A;  4HG0 A;  4PVH A;  1E0Y A;  2Y3S A;  1E8G A;  2I0K A;  2Q4W A;  2BVG A;  4PZF A;  2AXR A;  3C0P A;  3DED A;  3HSU A;  1VAO A;  2VFT A;  3FWA A;  1DIQ A;  3PQB A;  2VAO A;  1W1O A;  3FW9 A;  3ETR B;  3LAE A;  3TSJ A;  1E8H A;  3PM9 A;  1QLT A;  3TX1 A;  4PYT A;  5HHZ A;  3I99 A;  3RJA A;  3D2J A;  4PWB A;  5L6G A;  1N62 C;  4UD8 A;  4JB1 A;  3NVV B;  4ML8 A;  1FFU C;  1W1Q A;  2R2Z A;  2VFV A;  2Y4G A;  3S1F A;  2O3G A;  2Y08 A;  3W8Z A;  4BBY A;  2GQU A;  4PVE A;  3W8X A;  2OAI A;  4ZOH B;  1W1K A;  5L6F A;  2PLS A;  4BC7 A;  1AHV A;  1N5X A;  4PWC A;  2QKN A;  1V97 A;  3JS8 A;  2P13 A;  3BW7 A;  2Y3R A;  5I1W A;  1N63 C;  2R8D A;  2UUU A;  5AWV A;  3RJ8 A;  2W3S A;  2RK5 A;  5HMR A;  3AM9 A;  3LLB A;  1HSK A;  3EUB 3;  3FW8 A;  3NS1 B;  5I1V A;  1MBB A;  1F0X A;  2GQT A;  1W1L A;  1N60 C;  1QLU A;  5HQX A;  5G5G B;  5G5H B;  1JRO A;  5D79 A;  5FXE A;  5FXD A;  1UXY A;  2E3T A;  3VTE A;  2P3H A;  3KJM A;  2VFU A;  1T3Q C;  2P4P A;  3DQ0 A;  1W1R A;  4PVK A;  2VFR A;  4JAY A;  4OAL A;  1E8F A;  2NQW A;  1WVE A;  5FXP A;  3AN1 A;  2IPI A;  3NVZ B;  3NVY B;  1WVF A;  5AE2 A;  3W8W A;  4MLA A;  3B9J B;  4XLO A;  1WYG A;  1DII A;  2Q85 A;  3GSY A;  3NVW B;  1ZXI C;  1W1J A;  1MBT A;  2EXR A;  1AHU A;  1W1M A;  1ZR6 A;  5ADZ A;  4DNS A;  1N61 C;  3FW7 A;  4BCA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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