2I0KA

Cholesterol oxidase from brevibacterium sterolicum- his121ala mutant
Total Genus 175
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
556
structure length
536
Chain Sequence
b'APLPTPPNFPNDIALFQQAYQNWSKEIMLDATWVCSPKTPQDVVRLANWAHEHDYKIRPRGAMAGWTPLTVEKGANVEKVILADTMTHLNGITVNTGGPVATVTAGAGASIEAIVTELQKHDLGWANLPAPGVLSIGGALAVNAHGAALPAVGQTTLPGHTYGSLSNLVTELTAVVWNGTTYALETYQRNDPRITPLLTNLGRCFLTSVTMQAGPNFRQRCQSYTDIPWRELFAPKGADGRTFEKFVAESGGAEAIWYPFTEKPWMKVWTVSGKPPQAREVSGPYNYIFSDNLPEPITDMIGAINAGNPGIAPLFGPAMYEITKLGLAATNANDIWGWSKDVQFYIKATTLRLTEGGGAVVTSRANIATVINDFTEWFHERIEFYRAKGEFPLNGPVEIRCCGLDQAADVKVPSVGPPTISATRPRPDHPDWDVAIWLNVLGVPGTPGMFEFYREMEQWMRSHYNNDDATFRPEWSKGWAFGPDPYTDNDIVTNKMRATYIEGVPTTENWDTARARYNQIDPHRVFTNGFMDKLLP'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Oxidoreductase
molecule tags Oxidoreductase
source organism Brevibacterium sterolicum
publication title Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.
pubmed doi rcsb
total genus 175
structure length 536
sequence length 556
ec nomenclature ec 1.1.3.6: Cholesterol oxidase.
pdb deposition date 2006-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF09129 Chol_subst-bind Cholesterol oxidase, substrate-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2i0kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2i0kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2i0kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2i0kA03
4PWCA 3AMZA 1FFUC 1VDVA 2VFTA 2PLIA 2EXRA 1VAOA 1FO4A 3D2HA 1T3QC 3AM9A 3W8ZA 2VFUA 4BC7A 2PLSA 3C0PA 1MBTA 3HRDC 3DQ0A 2P13A 2VFRA 3D2JA 1E8GA 5HHZA 1N60C 1ZR6A 4BBYA 5FXEA 4PVEA 3NVYB 4UD8A 3FW8A 3BW7A 2GQUA 3GSYA 1W1QA 1DIIA 5AE3A 5D79A 1AHZA 5FXPA 1W1KA 2VAOA 1RM6B 4OALA 3LAEA 2W55A 2Q85A 3FWAA 3TSJA 2O3GA 5HMRA 2QPMA 3FW9A 4XLOA 3NRZB 3S1DA 1N63C 2MBRA 4PVJA 1JRPA 1QLTA 1FIQB 2Q4WA 1QLUA 2I0KA 3NS1B 3NVWB 5AE2A 3DEDA 1E8HA 4JB1A 1SB3B 2P3HA 3S1EA 1DZNA 3TX1A 1JROA 3PM9A 3KJMA 3S1CA 1HSKA 4PYTA 2BVFA 2AXRA 3EUB3 2GQTA 2QKNA 4DNSA 4ML8A 2NQWA 4O95A 1N61C 1AHVA 2P4PA 2R8DA 1N5WC 1I19A 5AE1A 3LLBA 1UXYA 2W54A 1E8FA 2OAIA 5FXFA 3D2DA 2R2ZA 1DIQA 3NVVB 5G5GB 2YVSA 3SR6B 2VFSA 4PVHA 5FXDA 3VTEA 1W1LA 3S1FA 3W8WA 5HQXA 1WVEA 2VFVA 4JAYA 4PWBA 3I99A 1W1JA 3W8XA 5G5HB 1FFVC 1W1SA 4MLAA 2E3TA 3ETRB 5ADZA 1F0XA 4HG0A 1ZXIC 2W3RA 3FW7A 1WVFA 1W1OA 2W3SA 2BVHA 2RK5A 1N62C 1N5XA 4BCAA 4EC3A 4PZFA 4ZOHB 2BVGA 1AHUA 4PVKA 1W1RA 1E0YA 3B9JB 3JS8A 4BC9A 1V97A 3AN1A 1WYGA 3NVZB 3TSHA 1W1MA 1MBBA
chains in the Genus database with same CATH superfamily
4PWCA 3AMZA 1FFUC 1VDVA 2VFTA 2PLIA 2EXRA 1VAOA 1FO4A 3D2HA 1T3QC 3AM9A 3W8ZA 2Y08A 2VFUA 4BC7A 2PLSA 3C0PA 1MBTA 3HRDC 3DQ0A 2P13A 2VFRA 3D2JA 1E8GA 5HHZA 1N60C 1ZR6A 4BBYA 3HSUA 5FXEA 3NVYB 4PVEA 4UD8A 2UUVA 3FW8A 3BW7A 2WDWA 2GQUA 3GSYA 1W1QA 1DIIA 5AE3A 5D79A 1AHZA 5FXPA 1W1KA 3RJAA 2VAOA 1RM6B 4OALA 3LAEA 2W55A 2Q85A 3FWAA 3TSJA 2O3GA 5I1WA 5HMRA 2QPMA 3FW9A 4XLOA 3NRZB 3S1DA 2Y4GA 2Y3RA 1N63C 2MBRA 4PVJA 1JRPA 1QLTA 1FIQB 2Q4WA 2IPIA 1QLUA 2I0KA 3NS1B 3NVWB 5AE2A 3DEDA 1E8HA 4JB1A 1SB3B 5L6FA 2P3HA 3S1EA 1DZNA 3TX1A 1JROA 3PM9A 3KJMA 3S1CA 1HSKA 4PYTA 2Y3SA 2BVFA 2AXRA 3EUB3 2GQTA 2QKNA 4DNSA 4ML8A 2NQWA 4O95A 2UUUA 1N61C 1AHVA 2P4PA 2R8DA 1N5WC 1I19A 5AE1A 3LLBA 1UXYA 2W54A 1E8FA 2OAIA 5FXFA 3D2DA 2R2ZA 3PQBA 5I1VA 1DIQA 3NVVB 5G5GB 2YVSA 3SR6B 2VFSA 4PVHA 5FXDA 3VTEA 1W1LA 3S1FA 3W8WA 5HQXA 1WVEA 3RJ8A 2VFVA 4JAYA 4PWBA 3POPA 3I99A 5K8EA 1W1JA 3W8XA 5G5HB 1FFVC 1W1SA 4MLAA 3EJBB 2E3TA 3ETRB 5ADZA 1F0XA 4HG0A 1ZXIC 2W3RA 3FW7A 1WVFA 3EJEB 5AWVA 1W1OA 2W3SA 2BVHA 2RK5A 1N62C 1N5XA 4BCAA 4EC3A 4PZFA 4ZOHB 2BVGA 1AHUA 4PVKA 3EJDB 1W1RA 1E0YA 3B9JB 3JS8A 4BC9A 1V97A 3AN1A 1WYGA 3NVZB 5L6GA 3TSHA 1W1MA 1MBBA
chains in the Genus database with same CATH topology
4PWCA 3AMZA 1FFUC 1VDVA 2VFTA 2PLIA 2EXRA 1VAOA 1FO4A 3D2HA 1T3QC 3AM9A 3W8ZA 2Y08A 2VFUA 4BC7A 2PLSA 3C0PA 1MBTA 3HRDC 3DQ0A 2P13A 2VFRA 3D2JA 1E8GA 5HHZA 1N60C 1ZR6A 4BBYA 3HSUA 5FXEA 4PVEA 3NVYB 4UD8A 2UUVA 3FW8A 3BW7A 2WDWA 2GQUA 3GSYA 1W1QA 1DIIA 5AE3A 5D79A 1AHZA 5FXPA 1W1KA 3RJAA 2VAOA 1RM6B 4OALA 3LAEA 2W55A 2Q85A 3FWAA 3TSJA 2O3GA 5I1WA 5HMRA 2QPMA 3FW9A 4XLOA 3NRZB 3S1DA 2Y4GA 2Y3RA 1N63C 2MBRA 4PVJA 1JRPA 1QLTA 1FIQB 2Q4WA 2IPIA 1QLUA 2I0KA 3NS1B 3NVWB 5AE2A 3DEDA 1E8HA 4JB1A 1SB3B 5L6FA 2P3HA 3S1EA 1DZNA 3TX1A 1JROA 3PM9A 3KJMA 3S1CA 1HSKA 4PYTA 2Y3SA 2BVFA 2AXRA 3EUB3 2GQTA 2QKNA 4DNSA 4ML8A 2NQWA 4O95A 2UUUA 1N61C 1AHVA 2P4PA 2R8DA 1N5WC 1I19A 5AE1A 3LLBA 1UXYA 2W54A 1E8FA 2OAIA 5FXFA 3D2DA 2R2ZA 3PQBA 5I1VA 1DIQA 3NVVB 5G5GB 2YVSA 3SR6B 2VFSA 4PVHA 5FXDA 3VTEA 1W1LA 3S1FA 3W8WA 5HQXA 1WVEA 3RJ8A 2VFVA 4JAYA 4PWBA 3POPA 3I99A 5K8EA 1W1JA 3W8XA 5G5HB 1FFVC 1W1SA 4MLAA 2E3TA 3ETRB 5ADZA 1F0XA 4HG0A 1ZXIC 2W3RA 3FW7A 1WVFA 5AWVA 1W1OA 2W3SA 2BVHA 2RK5A 1N62C 1N5XA 4BCAA 4EC3A 4PZFA 4ZOHB 2BVGA 1AHUA 4PVKA 1W1RA 1E0YA 3B9JB 3JS8A 4BC9A 1V97A 3AN1A 1WYGA 3NVZB 5L6GA 3TSHA 1W1MA 1MBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PWC A;  3AMZ A;  1FFU C;  1VDV A;  2VFT A;  2PLI A;  2EXR A;  1VAO A;  1FO4 A;  3D2H A;  1T3Q C;  3AM9 A;  3W8Z A;  2VFU A;  4BC7 A;  2PLS A;  3C0P A;  1MBT A;  3HRD C;  3DQ0 A;  2P13 A;  2VFR A;  3D2J A;  1E8G A;  5HHZ A;  1N60 C;  1ZR6 A;  4BBY A;  5FXE A;  4PVE A;  3NVY B;  4UD8 A;  3FW8 A;  3BW7 A;  2GQU A;  3GSY A;  1W1Q A;  1DII A;  5AE3 A;  5D79 A;  1AHZ A;  5FXP A;  1W1K A;  2VAO A;  1RM6 B;  4OAL A;  3LAE A;  2W55 A;  2Q85 A;  3FWA A;  3TSJ A;  2O3G A;  5HMR A;  2QPM A;  3FW9 A;  4XLO A;  3NRZ B;  3S1D A;  1N63 C;  2MBR A;  4PVJ A;  1JRP A;  1QLT A;  1FIQ B;  2Q4W A;  1QLU A;  2I0K A;  3NS1 B;  3NVW B;  5AE2 A;  3DED A;  1E8H A;  4JB1 A;  1SB3 B;  2P3H A;  3S1E A;  1DZN A;  3TX1 A;  1JRO A;  3PM9 A;  3KJM A;  3S1C A;  1HSK A;  4PYT A;  2BVF A;  2AXR A;  3EUB 3;  2GQT A;  2QKN A;  4DNS A;  4ML8 A;  2NQW A;  4O95 A;  1N61 C;  1AHV A;  2P4P A;  2R8D A;  1N5W C;  1I19 A;  5AE1 A;  3LLB A;  1UXY A;  2W54 A;  1E8F A;  2OAI A;  5FXF A;  3D2D A;  2R2Z A;  1DIQ A;  3NVV B;  5G5G B;  2YVS A;  3SR6 B;  2VFS A;  4PVH A;  5FXD A;  3VTE A;  1W1L A;  3S1F A;  3W8W A;  5HQX A;  1WVE A;  2VFV A;  4JAY A;  4PWB A;  3I99 A;  1W1J A;  3W8X A;  5G5H B;  1FFV C;  1W1S A;  4MLA A;  2E3T A;  3ETR B;  5ADZ A;  1F0X A;  4HG0 A;  1ZXI C;  2W3R A;  3FW7 A;  1WVF A;  1W1O A;  2W3S A;  2BVH A;  2RK5 A;  1N62 C;  1N5X A;  4BCA A;  4EC3 A;  4PZF A;  4ZOH B;  2BVG A;  1AHU A;  4PVK A;  1W1R A;  1E0Y A;  3B9J B;  3JS8 A;  4BC9 A;  1V97 A;  3AN1 A;  1WYG A;  3NVZ B;  3TSH A;  1W1M A;  1MBB A; 
#chains in the Genus database with same CATH topology
 4PWC A;  3AMZ A;  1FFU C;  1VDV A;  2VFT A;  2PLI A;  2EXR A;  1VAO A;  1FO4 A;  3D2H A;  1T3Q C;  3AM9 A;  3W8Z A;  2Y08 A;  2VFU A;  4BC7 A;  2PLS A;  3C0P A;  1MBT A;  3HRD C;  3DQ0 A;  2P13 A;  2VFR A;  3D2J A;  1E8G A;  5HHZ A;  1N60 C;  1ZR6 A;  4BBY A;  3HSU A;  5FXE A;  3NVY B;  4PVE A;  4UD8 A;  2UUV A;  3FW8 A;  3BW7 A;  2WDW A;  2GQU A;  3GSY A;  1W1Q A;  1DII A;  5AE3 A;  5D79 A;  1AHZ A;  5FXP A;  1W1K A;  3RJA A;  2VAO A;  1RM6 B;  4OAL A;  3LAE A;  2W55 A;  2Q85 A;  3FWA A;  3TSJ A;  2O3G A;  5I1W A;  5HMR A;  2QPM A;  3FW9 A;  4XLO A;  3NRZ B;  3S1D A;  2Y4G A;  2Y3R A;  1N63 C;  2MBR A;  4PVJ A;  1JRP A;  1QLT A;  1FIQ B;  2Q4W A;  2IPI A;  1QLU A;  2I0K A;  3NS1 B;  3NVW B;  5AE2 A;  3DED A;  1E8H A;  4JB1 A;  1SB3 B;  5L6F A;  2P3H A;  3S1E A;  1DZN A;  3TX1 A;  1JRO A;  3PM9 A;  3KJM A;  3S1C A;  1HSK A;  4PYT A;  2Y3S A;  2BVF A;  2AXR A;  3EUB 3;  2GQT A;  2QKN A;  4DNS A;  4ML8 A;  2NQW A;  4O95 A;  2UUU A;  1N61 C;  1AHV A;  2P4P A;  2R8D A;  1N5W C;  1I19 A;  5AE1 A;  3LLB A;  1UXY A;  2W54 A;  1E8F A;  2OAI A;  5FXF A;  3D2D A;  2R2Z A;  3PQB A;  5I1V A;  1DIQ A;  3NVV B;  5G5G B;  2YVS A;  3SR6 B;  2VFS A;  4PVH A;  5FXD A;  3VTE A;  1W1L A;  3S1F A;  3W8W A;  5HQX A;  1WVE A;  3RJ8 A;  2VFV A;  4JAY A;  4PWB A;  3POP A;  3I99 A;  5K8E A;  1W1J A;  3W8X A;  5G5H B;  1FFV C;  1W1S A;  4MLA A;  3EJB B;  2E3T A;  3ETR B;  5ADZ A;  1F0X A;  4HG0 A;  1ZXI C;  2W3R A;  3FW7 A;  1WVF A;  3EJE B;  5AWV A;  1W1O A;  2W3S A;  2BVH A;  2RK5 A;  1N62 C;  1N5X A;  4BCA A;  4EC3 A;  4PZF A;  4ZOH B;  2BVG A;  1AHU A;  4PVK A;  3EJD B;  1W1R A;  1E0Y A;  3B9J B;  3JS8 A;  4BC9 A;  1V97 A;  3AN1 A;  1WYG A;  3NVZ B;  5L6G A;  3TSH A;  1W1M A;  1MBB A; 
#chains in the Genus database with same CATH homology
 4PWC A;  3AMZ A;  1FFU C;  1VDV A;  2VFT A;  2PLI A;  2EXR A;  1VAO A;  1FO4 A;  3D2H A;  1T3Q C;  3AM9 A;  3W8Z A;  2Y08 A;  2VFU A;  4BC7 A;  2PLS A;  3C0P A;  1MBT A;  3HRD C;  3DQ0 A;  2P13 A;  2VFR A;  3D2J A;  1E8G A;  5HHZ A;  1N60 C;  1ZR6 A;  4BBY A;  3HSU A;  5FXE A;  4PVE A;  3NVY B;  4UD8 A;  2UUV A;  3FW8 A;  3BW7 A;  2WDW A;  2GQU A;  3GSY A;  1W1Q A;  1DII A;  5AE3 A;  5D79 A;  1AHZ A;  5FXP A;  1W1K A;  3RJA A;  2VAO A;  1RM6 B;  4OAL A;  3LAE A;  2W55 A;  2Q85 A;  3FWA A;  3TSJ A;  2O3G A;  5I1W A;  5HMR A;  2QPM A;  3FW9 A;  4XLO A;  3NRZ B;  3S1D A;  2Y4G A;  2Y3R A;  1N63 C;  2MBR A;  4PVJ A;  1JRP A;  1QLT A;  1FIQ B;  2Q4W A;  2IPI A;  1QLU A;  2I0K A;  3NS1 B;  3NVW B;  5AE2 A;  3DED A;  1E8H A;  4JB1 A;  1SB3 B;  5L6F A;  2P3H A;  3S1E A;  1DZN A;  3TX1 A;  1JRO A;  3PM9 A;  3KJM A;  3S1C A;  1HSK A;  4PYT A;  2Y3S A;  2BVF A;  2AXR A;  3EUB 3;  2GQT A;  2QKN A;  4DNS A;  4ML8 A;  2NQW A;  4O95 A;  2UUU A;  1N61 C;  1AHV A;  2P4P A;  2R8D A;  1N5W C;  1I19 A;  5AE1 A;  3LLB A;  1UXY A;  2W54 A;  1E8F A;  2OAI A;  5FXF A;  3D2D A;  2R2Z A;  3PQB A;  5I1V A;  1DIQ A;  3NVV B;  5G5G B;  2YVS A;  3SR6 B;  2VFS A;  4PVH A;  5FXD A;  3VTE A;  1W1L A;  3S1F A;  3W8W A;  5HQX A;  1WVE A;  3RJ8 A;  2VFV A;  4JAY A;  4PWB A;  3POP A;  3I99 A;  5K8E A;  1W1J A;  3W8X A;  5G5H B;  1FFV C;  1W1S A;  4MLA A;  2E3T A;  3ETR B;  5ADZ A;  1F0X A;  4HG0 A;  1ZXI C;  2W3R A;  3FW7 A;  1WVF A;  5AWV A;  1W1O A;  2W3S A;  2BVH A;  2RK5 A;  1N62 C;  1N5X A;  4BCA A;  4EC3 A;  4PZF A;  4ZOH B;  2BVG A;  1AHU A;  4PVK A;  1W1R A;  1E0Y A;  3B9J B;  3JS8 A;  4BC9 A;  1V97 A;  3AN1 A;  1WYG A;  3NVZ B;  5L6G A;  3TSH A;  1W1M A;  1MBB A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...