2I0KA

Cholesterol oxidase from brevibacterium sterolicum- his121ala mutant
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
556
structure length
536
Chain Sequence
APLPTPPNFPNDIALFQQAYQNWSKEIMLDATWVCSPKTPQDVVRLANWAHEHDYKIRPRGAMAGWTPLTVEKGANVEKVILADTMTHLNGITVNTGGPVATVTAGAGASIEAIVTELQKHDLGWANLPAPGVLSIGGALAVNAHGAALPAVGQTTLPGHTYGSLSNLVTELTAVVWNGTTYALETYQRNDPRITPLLTNLGRCFLTSVTMQAGPNFRQRCQSYTDIPWRELFAPKGADGRTFEKFVAESGGAEAIWYPFTEKPWMKVWTVSGKPPQAREVSGPYNYIFSDNLPEPITDMIGAINAGNPGIAPLFGPAMYEITKLGLAATNANDIWGWSKDVQFYIKATTLRLTEGGGAVVTSRANIATVINDFTEWFHERIEFYRAKGEFPLNGPVEIRCCGLDQAADVKVPSVGPPTISATRPRPDHPDWDVAIWLNVLGVPGTPGMFEFYREMEQWMRSHYNNDDATFRPEWSKGWAFGPDPYTDNDIVTNKMRATYIEGVPTTENWDTARARYNQIDPHRVFTNGFMDKLLP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Oxidoreductase
publication title Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.
pubmed doi rcsb
source organism Brevibacterium sterolicum
molecule tags Oxidoreductase
total genus 175
structure length 536
sequence length 556
ec nomenclature ec 1.1.3.6: Cholesterol oxidase.
pdb deposition date 2006-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF09129 Chol_subst-bind Cholesterol oxidase, substrate-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2i0kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2i0kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2i0kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2i0kA03
3C0PA 1I19A 2P3HA 3GSYA 3DEDA 1JROA 3D2DA 2W3SA 2VFVA 3W8ZA 4BC7A 1E0YA 1N60C 2Q4WA 4PVEA 1AHZA 3KJMA 2MBRA 5FXEA 2AXRA 4JAYA 5G5HB 2VAOA 4PVKA 1DZNA 3TSHA 1ZXIC 2NQWA 2O3GA 1W1SA 1WVFA 1N63C 3S1CA 1QLTA 1ZR6A 1VDVA 3NS1B 1W1LA 4OALA 1UXYA 4ZOHB 2PLIA 4PWBA 1AHVA 2I0KA 3W8WA 1E8GA 4ML8A 3NVZB 5D79A 1F0XA 3S1DA 1E8FA 2GQTA 4BCAA 2EXRA 1V97A 1QLUA 4JB1A 2W54A 4PYTA 4O95A 3SR6B 3S1FA 5HMRA 2VFSA 2W3RA 1W1QA 2QKNA 4PVHA 2R8DA 3PM9A 4HG0A 1MBTA 3EUB3 1HSKA 1N5WC 1FIQB 4MLAA 3AN1A 3TX1A 3AMZA 1WVEA 2BVFA 1WYGA 2QPMA 1N62C 4PVJA 4DNSA 3FW9A 3VTEA 4PZFA 3FW8A 2OAIA 3I99A 1W1JA 2YVSA 4PWCA 5G5GB 3NVYB 3JS8A 4UD8A 3W8XA 3D2HA 2RK5A 1FO4A 4XLOA 4EC3A 2W55A 3DQ0A 5HQXA 3HRDC 2Q85A 4BC9A 2VFTA 4BBYA 3BW7A 1MBBA 3AM9A 3S1EA 1FFUC 1W1KA 2GQUA 1DIQA 3TSJA 1W1MA 1AHUA 5FXFA 2BVHA 3LLBA 2BVGA 1N61C 5AE3A 5FXDA 3ETRB 1VAOA 5HHZA 3NVVB 3NVWB 1T3QC 1DIIA 2P4PA 5FXPA 1JRPA 2PLSA 1E8HA 5AE1A 5ADZA 3FWAA 3NRZB 2P13A 3LAEA 5AE2A 2R2ZA 2E3TA 1N5XA 1RM6B 3B9JB 2VFUA 1SB3B 1W1OA 3D2JA 2VFRA 1FFVC 3FW7A 1W1RA
chains in the Genus database with same CATH superfamily
3C0PA 1I19A 2P3HA 3GSYA 3DEDA 3HSUA 1JROA 3D2DA 2W3SA 2VFVA 3W8ZA 4BC7A 1E0YA 1N60C 2Q4WA 4PVEA 1AHZA 3KJMA 2MBRA 5FXEA 2AXRA 4JAYA 5G5HB 2VAOA 4PVKA 1DZNA 3TSHA 2Y3RA 5I1VA 1ZXIC 2NQWA 2Y4GA 2Y3SA 2O3GA 1W1SA 5K8EA 1WVFA 1N63C 3S1CA 1QLTA 1ZR6A 1VDVA 3NS1B 1W1LA 4OALA 1UXYA 4ZOHB 2PLIA 4PWBA 1AHVA 2I0KA 3W8WA 1E8GA 4ML8A 3NVZB 5D79A 1F0XA 2WDWA 3S1DA 1E8FA 2GQTA 4BCAA 2EXRA 1V97A 1QLUA 4JB1A 2W54A 4PYTA 4O95A 3SR6B 3S1FA 5HMRA 2VFSA 2W3RA 1W1QA 2QKNA 4PVHA 2R8DA 3PM9A 4HG0A 1MBTA 3EUB3 1HSKA 1N5WC 1FIQB 2Y08A 4MLAA 3AN1A 3TX1A 3AMZA 1WVEA 2BVFA 5I1WA 5L6GA 1WYGA 2QPMA 1N62C 4PVJA 4DNSA 3FW9A 3VTEA 4PZFA 3FW8A 2OAIA 3PQBA 3EJEB 2IPIA 3I99A 1W1JA 2YVSA 4PWCA 5G5GB 3NVYB 3JS8A 4UD8A 3W8XA 3D2HA 2RK5A 1FO4A 4XLOA 4EC3A 5AWVA 2W55A 3DQ0A 5HQXA 3HRDC 2Q85A 4BC9A 2VFTA 4BBYA 3BW7A 1MBBA 3AM9A 3S1EA 1FFUC 1W1KA 2GQUA 1DIQA 3TSJA 1W1MA 1AHUA 5FXFA 2BVHA 3RJ8A 3LLBA 2BVGA 1N61C 5AE3A 5FXDA 3ETRB 1VAOA 3NVVB 5HHZA 3NVWB 1T3QC 1DIIA 2UUVA 5L6FA 2P4PA 5FXPA 1JRPA 2PLSA 2UUUA 1E8HA 3RJAA 5AE1A 5ADZA 3FWAA 3NRZB 3POPA 2P13A 3LAEA 5AE2A 2R2ZA 3EJDB 2E3TA 1N5XA 1RM6B 3EJBB 3B9JB 2VFUA 1SB3B 1W1OA 3D2JA 2VFRA 1FFVC 3FW7A 1W1RA
chains in the Genus database with same CATH topology
3C0PA 1I19A 2P3HA 3GSYA 3DEDA 3HSUA 1JROA 3D2DA 2W3SA 2VFVA 3W8ZA 4BC7A 1E0YA 1N60C 2Q4WA 4PVEA 1AHZA 3KJMA 2MBRA 5FXEA 2AXRA 4JAYA 5G5HB 2VAOA 4PVKA 1DZNA 3TSHA 2Y3RA 5I1VA 1ZXIC 2NQWA 2Y4GA 2Y3SA 2O3GA 1W1SA 5K8EA 1WVFA 1N63C 3S1CA 1QLTA 1ZR6A 1VDVA 3NS1B 1W1LA 4OALA 1UXYA 4ZOHB 2PLIA 4PWBA 1AHVA 2I0KA 3W8WA 1E8GA 4ML8A 3NVZB 5D79A 1F0XA 2WDWA 3S1DA 1E8FA 2GQTA 4BCAA 2EXRA 1V97A 1QLUA 4JB1A 2W54A 4PYTA 4O95A 3SR6B 3S1FA 5HMRA 2VFSA 2W3RA 1W1QA 2QKNA 4PVHA 2R8DA 3PM9A 4HG0A 1MBTA 3EUB3 1HSKA 1N5WC 1FIQB 2Y08A 4MLAA 3AN1A 3TX1A 3AMZA 1WVEA 2BVFA 5I1WA 5L6GA 1WYGA 2QPMA 1N62C 4PVJA 4DNSA 3FW9A 3VTEA 4PZFA 3FW8A 2OAIA 3PQBA 2IPIA 3I99A 1W1JA 2YVSA 4PWCA 5G5GB 3NVYB 3JS8A 4UD8A 3W8XA 3D2HA 2RK5A 1FO4A 4XLOA 4EC3A 5AWVA 2W55A 3DQ0A 5HQXA 3HRDC 2Q85A 4BC9A 2VFTA 4BBYA 3BW7A 1MBBA 3AM9A 3S1EA 1FFUC 1W1KA 2GQUA 1DIQA 3TSJA 1W1MA 1AHUA 5FXFA 2BVHA 3RJ8A 3LLBA 2BVGA 1N61C 5AE3A 5FXDA 3ETRB 1VAOA 5HHZA 3NVVB 3NVWB 1T3QC 1DIIA 2UUVA 5L6FA 2P4PA 5FXPA 1JRPA 2PLSA 2UUUA 1E8HA 3RJAA 5AE1A 5ADZA 3FWAA 3NRZB 3POPA 2P13A 3LAEA 5AE2A 2R2ZA 2E3TA 1N5XA 1RM6B 3B9JB 2VFUA 1SB3B 1W1OA 3D2JA 2VFRA 1FFVC 3FW7A 1W1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C0P A;  1I19 A;  2P3H A;  3GSY A;  3DED A;  1JRO A;  3D2D A;  2W3S A;  2VFV A;  3W8Z A;  4BC7 A;  1E0Y A;  1N60 C;  2Q4W A;  4PVE A;  1AHZ A;  3KJM A;  2MBR A;  5FXE A;  2AXR A;  4JAY A;  5G5H B;  2VAO A;  4PVK A;  1DZN A;  3TSH A;  1ZXI C;  2NQW A;  2O3G A;  1W1S A;  1WVF A;  1N63 C;  3S1C A;  1QLT A;  1ZR6 A;  1VDV A;  3NS1 B;  1W1L A;  4OAL A;  1UXY A;  4ZOH B;  2PLI A;  4PWB A;  1AHV A;  2I0K A;  3W8W A;  1E8G A;  4ML8 A;  3NVZ B;  5D79 A;  1F0X A;  3S1D A;  1E8F A;  2GQT A;  4BCA A;  2EXR A;  1V97 A;  1QLU A;  4JB1 A;  2W54 A;  4PYT A;  4O95 A;  3SR6 B;  3S1F A;  5HMR A;  2VFS A;  2W3R A;  1W1Q A;  2QKN A;  4PVH A;  2R8D A;  3PM9 A;  4HG0 A;  1MBT A;  3EUB 3;  1HSK A;  1N5W C;  1FIQ B;  4MLA A;  3AN1 A;  3TX1 A;  3AMZ A;  1WVE A;  2BVF A;  1WYG A;  2QPM A;  1N62 C;  4PVJ A;  4DNS A;  3FW9 A;  3VTE A;  4PZF A;  3FW8 A;  2OAI A;  3I99 A;  1W1J A;  2YVS A;  4PWC A;  5G5G B;  3NVY B;  3JS8 A;  4UD8 A;  3W8X A;  3D2H A;  2RK5 A;  1FO4 A;  4XLO A;  4EC3 A;  2W55 A;  3DQ0 A;  5HQX A;  3HRD C;  2Q85 A;  4BC9 A;  2VFT A;  4BBY A;  3BW7 A;  1MBB A;  3AM9 A;  3S1E A;  1FFU C;  1W1K A;  2GQU A;  1DIQ A;  3TSJ A;  1W1M A;  1AHU A;  5FXF A;  2BVH A;  3LLB A;  2BVG A;  1N61 C;  5AE3 A;  5FXD A;  3ETR B;  1VAO A;  5HHZ A;  3NVV B;  3NVW B;  1T3Q C;  1DII A;  2P4P A;  5FXP A;  1JRP A;  2PLS A;  1E8H A;  5AE1 A;  5ADZ A;  3FWA A;  3NRZ B;  2P13 A;  3LAE A;  5AE2 A;  2R2Z A;  2E3T A;  1N5X A;  1RM6 B;  3B9J B;  2VFU A;  1SB3 B;  1W1O A;  3D2J A;  2VFR A;  1FFV C;  3FW7 A;  1W1R A; 
#chains in the Genus database with same CATH topology
 3C0P A;  1I19 A;  2P3H A;  3GSY A;  3DED A;  3HSU A;  1JRO A;  3D2D A;  2W3S A;  2VFV A;  3W8Z A;  4BC7 A;  1E0Y A;  1N60 C;  2Q4W A;  4PVE A;  1AHZ A;  3KJM A;  2MBR A;  5FXE A;  2AXR A;  4JAY A;  5G5H B;  2VAO A;  4PVK A;  1DZN A;  3TSH A;  2Y3R A;  5I1V A;  1ZXI C;  2NQW A;  2Y4G A;  2Y3S A;  2O3G A;  1W1S A;  5K8E A;  1WVF A;  1N63 C;  3S1C A;  1QLT A;  1ZR6 A;  1VDV A;  3NS1 B;  1W1L A;  4OAL A;  1UXY A;  4ZOH B;  2PLI A;  4PWB A;  1AHV A;  2I0K A;  3W8W A;  1E8G A;  4ML8 A;  3NVZ B;  5D79 A;  1F0X A;  2WDW A;  3S1D A;  1E8F A;  2GQT A;  4BCA A;  2EXR A;  1V97 A;  1QLU A;  4JB1 A;  2W54 A;  4PYT A;  4O95 A;  3SR6 B;  3S1F A;  5HMR A;  2VFS A;  2W3R A;  1W1Q A;  2QKN A;  4PVH A;  2R8D A;  3PM9 A;  4HG0 A;  1MBT A;  3EUB 3;  1HSK A;  1N5W C;  1FIQ B;  2Y08 A;  4MLA A;  3AN1 A;  3TX1 A;  3AMZ A;  1WVE A;  2BVF A;  5I1W A;  5L6G A;  1WYG A;  2QPM A;  1N62 C;  4PVJ A;  4DNS A;  3FW9 A;  3VTE A;  4PZF A;  3FW8 A;  2OAI A;  3PQB A;  3EJE B;  2IPI A;  3I99 A;  1W1J A;  2YVS A;  4PWC A;  5G5G B;  3NVY B;  3JS8 A;  4UD8 A;  3W8X A;  3D2H A;  2RK5 A;  1FO4 A;  4XLO A;  4EC3 A;  5AWV A;  2W55 A;  3DQ0 A;  5HQX A;  3HRD C;  2Q85 A;  4BC9 A;  2VFT A;  4BBY A;  3BW7 A;  1MBB A;  3AM9 A;  3S1E A;  1FFU C;  1W1K A;  2GQU A;  1DIQ A;  3TSJ A;  1W1M A;  1AHU A;  5FXF A;  2BVH A;  3RJ8 A;  3LLB A;  2BVG A;  1N61 C;  5AE3 A;  5FXD A;  3ETR B;  1VAO A;  3NVV B;  5HHZ A;  3NVW B;  1T3Q C;  1DII A;  2UUV A;  5L6F A;  2P4P A;  5FXP A;  1JRP A;  2PLS A;  2UUU A;  1E8H A;  3RJA A;  5AE1 A;  5ADZ A;  3FWA A;  3NRZ B;  3POP A;  2P13 A;  3LAE A;  5AE2 A;  2R2Z A;  3EJD B;  2E3T A;  1N5X A;  1RM6 B;  3EJB B;  3B9J B;  2VFU A;  1SB3 B;  1W1O A;  3D2J A;  2VFR A;  1FFV C;  3FW7 A;  1W1R A; 
#chains in the Genus database with same CATH homology
 3C0P A;  1I19 A;  2P3H A;  3GSY A;  3DED A;  3HSU A;  1JRO A;  3D2D A;  2W3S A;  2VFV A;  3W8Z A;  4BC7 A;  1E0Y A;  1N60 C;  2Q4W A;  4PVE A;  1AHZ A;  3KJM A;  2MBR A;  5FXE A;  2AXR A;  4JAY A;  5G5H B;  2VAO A;  4PVK A;  1DZN A;  3TSH A;  2Y3R A;  5I1V A;  1ZXI C;  2NQW A;  2Y4G A;  2Y3S A;  2O3G A;  1W1S A;  5K8E A;  1WVF A;  1N63 C;  3S1C A;  1QLT A;  1ZR6 A;  1VDV A;  3NS1 B;  1W1L A;  4OAL A;  1UXY A;  4ZOH B;  2PLI A;  4PWB A;  1AHV A;  2I0K A;  3W8W A;  1E8G A;  4ML8 A;  3NVZ B;  5D79 A;  1F0X A;  2WDW A;  3S1D A;  1E8F A;  2GQT A;  4BCA A;  2EXR A;  1V97 A;  1QLU A;  4JB1 A;  2W54 A;  4PYT A;  4O95 A;  3SR6 B;  3S1F A;  5HMR A;  2VFS A;  2W3R A;  1W1Q A;  2QKN A;  4PVH A;  2R8D A;  3PM9 A;  4HG0 A;  1MBT A;  3EUB 3;  1HSK A;  1N5W C;  1FIQ B;  2Y08 A;  4MLA A;  3AN1 A;  3TX1 A;  3AMZ A;  1WVE A;  2BVF A;  5I1W A;  5L6G A;  1WYG A;  2QPM A;  1N62 C;  4PVJ A;  4DNS A;  3FW9 A;  3VTE A;  4PZF A;  3FW8 A;  2OAI A;  3PQB A;  2IPI A;  3I99 A;  1W1J A;  2YVS A;  4PWC A;  5G5G B;  3NVY B;  3JS8 A;  4UD8 A;  3W8X A;  3D2H A;  2RK5 A;  1FO4 A;  4XLO A;  4EC3 A;  5AWV A;  2W55 A;  3DQ0 A;  5HQX A;  3HRD C;  2Q85 A;  4BC9 A;  2VFT A;  4BBY A;  3BW7 A;  1MBB A;  3AM9 A;  3S1E A;  1FFU C;  1W1K A;  2GQU A;  1DIQ A;  3TSJ A;  1W1M A;  1AHU A;  5FXF A;  2BVH A;  3RJ8 A;  3LLB A;  2BVG A;  1N61 C;  5AE3 A;  5FXD A;  3ETR B;  1VAO A;  5HHZ A;  3NVV B;  3NVW B;  1T3Q C;  1DII A;  2UUV A;  5L6F A;  2P4P A;  5FXP A;  1JRP A;  2PLS A;  2UUU A;  1E8H A;  3RJA A;  5AE1 A;  5ADZ A;  3FWA A;  3NRZ B;  3POP A;  2P13 A;  3LAE A;  5AE2 A;  2R2Z A;  2E3T A;  1N5X A;  1RM6 B;  3B9J B;  2VFU A;  1SB3 B;  1W1O A;  3D2J A;  2VFR A;  1FFV C;  3FW7 A;  1W1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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