1W1MA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: glu502gly mutant
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGGYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 172
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1mA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1mA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1mA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1mA03
3LAEA 1SB3B 4BC9A 3S1DA 1QLUA 2VFRA 5FXFA 1V97A 5G5GB 2PLIA 1N5XA 4O95A 3DEDA 2Q85A 1E0YA 3NVVB 2O3GA 2I0KA 2W55A 5G5HB 3D2JA 3TSJA 2YVSA 5AE2A 1UXYA 2W3RA 2P13A 5ADZA 3I99A 2W3SA 1AHVA 1QLTA 2Q4WA 5AE3A 2NQWA 5HQXA 2VFSA 2OAIA 4MLAA 1AHUA 2R2ZA 3B9JB 3EUB3 2RK5A 1N63C 2BVHA 3C0PA 2EXRA 5FXPA 4DNSA 4HG0A 1N5WC 2BVFA 2R8DA 5D79A 5HMRA 3FWAA 1W1MA 4PZFA 1VDVA 3TX1A 1FFVC 1W1RA 4PVHA 1JROA 1ZR6A 3S1EA 4XLOA 1HSKA 3FW8A 5AE1A 2VAOA 3NS1B 4PVKA 4PWBA 3W8WA 4OALA 3HRDC 1AHZA 4UD8A 1W1JA 1FFUC 3D2DA 3KJMA 3AMZA 3NRZB 1WVEA 1F0XA 1E8FA 1E8HA 3S1CA 3NVYB 4ML8A 1RM6B 1N62C 2GQUA 4ZOHB 3W8ZA 3NVWB 2GQTA 4JB1A 4PYTA 3VTEA 1W1LA 1DZNA 2QPMA 3AN1A 1T3QC 4JAYA 2E3TA 2VFUA 3FW9A 1FO4A 1W1KA 3GSYA 3JS8A 1JRPA 2VFTA 3BW7A 1MBBA 3D2HA 1ZXIC 1E8GA 1MBTA 4PVEA 1WYGA 2P3HA 2PLSA 2QKNA 5FXEA 1VAOA 3ETRB 2AXRA 1N61C 4BBYA 1DIIA 3DQ0A 2MBRA 3FW7A 1WVFA 1N60C 5HHZA 3W8XA 2W54A 1W1SA 3AM9A 3S1FA 1DIQA 2VFVA 4PVJA 3LLBA 3SR6B 4BC7A 4PWCA 3PM9A 4BCAA 1I19A 1FIQB 4EC3A 5FXDA 3TSHA 1W1QA 1W1OA 2BVGA 3NVZB 2P4PA
chains in the Genus database with same CATH superfamily
3LAEA 1SB3B 4BC9A 5L6GA 3S1DA 1QLUA 2VFRA 5FXFA 1V97A 5G5GB 2PLIA 1N5XA 4O95A 3DEDA 2Q85A 1E0YA 3NVVB 2O3GA 2I0KA 2W55A 5G5HB 3D2JA 3TSJA 2YVSA 5AE2A 1UXYA 2W3RA 2P13A 5ADZA 3EJEB 3I99A 2W3SA 1AHVA 1QLTA 2Q4WA 5AE3A 2NQWA 2UUVA 2WDWA 3RJAA 5HQXA 2VFSA 2OAIA 4MLAA 5K8EA 1AHUA 2R2ZA 3B9JB 3EUB3 3HSUA 2RK5A 1N63C 2BVHA 3C0PA 2EXRA 5FXPA 4DNSA 4HG0A 1N5WC 2BVFA 2R8DA 5I1WA 5AWVA 5D79A 5HMRA 3FWAA 1W1MA 4PZFA 1VDVA 3TX1A 1FFVC 1W1RA 4PVHA 1JROA 1ZR6A 3S1EA 4XLOA 1HSKA 3FW8A 3EJDB 5AE1A 5L6FA 2VAOA 3NS1B 4PVKA 4PWBA 3W8WA 4OALA 3HRDC 1AHZA 2Y3SA 4UD8A 3PQBA 1W1JA 1FFUC 3D2DA 3KJMA 3AMZA 3NRZB 5I1VA 1WVEA 1F0XA 1E8FA 1E8HA 3S1CA 3NVYB 4ML8A 1RM6B 1N62C 2GQUA 4ZOHB 3W8ZA 3NVWB 2GQTA 4JB1A 4PYTA 3VTEA 1W1LA 3EJBB 1DZNA 2QPMA 3AN1A 1T3QC 4JAYA 2E3TA 2VFUA 3FW9A 1FO4A 1W1KA 3GSYA 3JS8A 1JRPA 2VFTA 3BW7A 1MBBA 3D2HA 1ZXIC 2Y4GA 1E8GA 1MBTA 4PVEA 1WYGA 2P3HA 2PLSA 3POPA 2QKNA 5FXEA 1VAOA 3ETRB 2Y3RA 2AXRA 1N61C 4BBYA 1DIIA 3DQ0A 2UUUA 2MBRA 3FW7A 1WVFA 1N60C 5HHZA 3W8XA 2W54A 1W1SA 3AM9A 3S1FA 1DIQA 2VFVA 4PVJA 3LLBA 3SR6B 4BC7A 4PWCA 3PM9A 3RJ8A 4BCAA 1I19A 1FIQB 4EC3A 5FXDA 2Y08A 2IPIA 3TSHA 1W1QA 1W1OA 2BVGA 3NVZB 2P4PA
chains in the Genus database with same CATH topology
3LAEA 1SB3B 4BC9A 5L6GA 3S1DA 1QLUA 2VFRA 5FXFA 1V97A 5G5GB 2PLIA 1N5XA 4O95A 3DEDA 2Q85A 1E0YA 3NVVB 2O3GA 2I0KA 2W55A 5G5HB 3D2JA 3TSJA 2YVSA 5AE2A 1UXYA 2W3RA 2P13A 5ADZA 3I99A 2W3SA 1AHVA 1QLTA 2Q4WA 5AE3A 2NQWA 2UUVA 2WDWA 3RJAA 5HQXA 2VFSA 2OAIA 4MLAA 5K8EA 1AHUA 2R2ZA 3B9JB 3EUB3 3HSUA 2RK5A 1N63C 2BVHA 3C0PA 2EXRA 5FXPA 4DNSA 4HG0A 1N5WC 2BVFA 2R8DA 5I1WA 5AWVA 5D79A 5HMRA 3FWAA 1W1MA 4PZFA 1VDVA 3TX1A 1FFVC 1W1RA 4PVHA 1JROA 1ZR6A 3S1EA 4XLOA 1HSKA 3FW8A 5AE1A 5L6FA 2VAOA 3NS1B 4PVKA 4PWBA 3W8WA 4OALA 3HRDC 1AHZA 2Y3SA 4UD8A 3PQBA 1W1JA 1FFUC 3D2DA 3KJMA 3AMZA 3NRZB 5I1VA 1WVEA 1F0XA 1E8FA 1E8HA 3S1CA 3NVYB 4ML8A 1RM6B 1N62C 2GQUA 4ZOHB 3W8ZA 3NVWB 2GQTA 4JB1A 4PYTA 3VTEA 1W1LA 1DZNA 2QPMA 3AN1A 1T3QC 4JAYA 2E3TA 2VFUA 3FW9A 1FO4A 1W1KA 3GSYA 3JS8A 1JRPA 2VFTA 3BW7A 1MBBA 3D2HA 1ZXIC 2Y4GA 1E8GA 1MBTA 4PVEA 1WYGA 2P3HA 2PLSA 3POPA 2QKNA 5FXEA 1VAOA 3ETRB 2Y3RA 2AXRA 1N61C 4BBYA 1DIIA 3DQ0A 2UUUA 2MBRA 3FW7A 1WVFA 1N60C 5HHZA 3W8XA 2W54A 1W1SA 3AM9A 3S1FA 1DIQA 2VFVA 4PVJA 3LLBA 3SR6B 4BC7A 4PWCA 3PM9A 3RJ8A 4BCAA 1I19A 1FIQB 4EC3A 5FXDA 2Y08A 2IPIA 3TSHA 1W1QA 1W1OA 2BVGA 3NVZB 2P4PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LAE A;  1SB3 B;  4BC9 A;  3S1D A;  1QLU A;  2VFR A;  5FXF A;  1V97 A;  5G5G B;  2PLI A;  1N5X A;  4O95 A;  3DED A;  2Q85 A;  1E0Y A;  3NVV B;  2O3G A;  2I0K A;  2W55 A;  5G5H B;  3D2J A;  3TSJ A;  2YVS A;  5AE2 A;  1UXY A;  2W3R A;  2P13 A;  5ADZ A;  3I99 A;  2W3S A;  1AHV A;  1QLT A;  2Q4W A;  5AE3 A;  2NQW A;  5HQX A;  2VFS A;  2OAI A;  4MLA A;  1AHU A;  2R2Z A;  3B9J B;  3EUB 3;  2RK5 A;  1N63 C;  2BVH A;  3C0P A;  2EXR A;  5FXP A;  4DNS A;  4HG0 A;  1N5W C;  2BVF A;  2R8D A;  5D79 A;  5HMR A;  3FWA A;  1W1M A;  4PZF A;  1VDV A;  3TX1 A;  1FFV C;  1W1R A;  4PVH A;  1JRO A;  1ZR6 A;  3S1E A;  4XLO A;  1HSK A;  3FW8 A;  5AE1 A;  2VAO A;  3NS1 B;  4PVK A;  4PWB A;  3W8W A;  4OAL A;  3HRD C;  1AHZ A;  4UD8 A;  1W1J A;  1FFU C;  3D2D A;  3KJM A;  3AMZ A;  3NRZ B;  1WVE A;  1F0X A;  1E8F A;  1E8H A;  3S1C A;  3NVY B;  4ML8 A;  1RM6 B;  1N62 C;  2GQU A;  4ZOH B;  3W8Z A;  3NVW B;  2GQT A;  4JB1 A;  4PYT A;  3VTE A;  1W1L A;  1DZN A;  2QPM A;  3AN1 A;  1T3Q C;  4JAY A;  2E3T A;  2VFU A;  3FW9 A;  1FO4 A;  1W1K A;  3GSY A;  3JS8 A;  1JRP A;  2VFT A;  3BW7 A;  1MBB A;  3D2H A;  1ZXI C;  1E8G A;  1MBT A;  4PVE A;  1WYG A;  2P3H A;  2PLS A;  2QKN A;  5FXE A;  1VAO A;  3ETR B;  2AXR A;  1N61 C;  4BBY A;  1DII A;  3DQ0 A;  2MBR A;  3FW7 A;  1WVF A;  1N60 C;  5HHZ A;  3W8X A;  2W54 A;  1W1S A;  3AM9 A;  3S1F A;  1DIQ A;  2VFV A;  4PVJ A;  3LLB A;  3SR6 B;  4BC7 A;  4PWC A;  3PM9 A;  4BCA A;  1I19 A;  1FIQ B;  4EC3 A;  5FXD A;  3TSH A;  1W1Q A;  1W1O A;  2BVG A;  3NVZ B;  2P4P A; 
#chains in the Genus database with same CATH topology
 3LAE A;  1SB3 B;  4BC9 A;  5L6G A;  3S1D A;  1QLU A;  2VFR A;  5FXF A;  1V97 A;  5G5G B;  2PLI A;  1N5X A;  4O95 A;  3DED A;  2Q85 A;  1E0Y A;  3NVV B;  2O3G A;  2I0K A;  2W55 A;  5G5H B;  3D2J A;  3TSJ A;  2YVS A;  5AE2 A;  1UXY A;  2W3R A;  2P13 A;  5ADZ A;  3EJE B;  3I99 A;  2W3S A;  1AHV A;  1QLT A;  2Q4W A;  5AE3 A;  2NQW A;  2UUV A;  2WDW A;  3RJA A;  5HQX A;  2VFS A;  2OAI A;  4MLA A;  5K8E A;  1AHU A;  2R2Z A;  3B9J B;  3EUB 3;  3HSU A;  2RK5 A;  1N63 C;  2BVH A;  3C0P A;  2EXR A;  5FXP A;  4DNS A;  4HG0 A;  1N5W C;  2BVF A;  2R8D A;  5I1W A;  5AWV A;  5D79 A;  5HMR A;  3FWA A;  1W1M A;  4PZF A;  1VDV A;  3TX1 A;  1FFV C;  1W1R A;  4PVH A;  1JRO A;  1ZR6 A;  3S1E A;  4XLO A;  1HSK A;  3FW8 A;  3EJD B;  5AE1 A;  5L6F A;  2VAO A;  3NS1 B;  4PVK A;  4PWB A;  3W8W A;  4OAL A;  3HRD C;  1AHZ A;  2Y3S A;  4UD8 A;  3PQB A;  1W1J A;  1FFU C;  3D2D A;  3KJM A;  3AMZ A;  3NRZ B;  5I1V A;  1WVE A;  1F0X A;  1E8F A;  1E8H A;  3S1C A;  3NVY B;  4ML8 A;  1RM6 B;  1N62 C;  2GQU A;  4ZOH B;  3W8Z A;  3NVW B;  2GQT A;  4JB1 A;  4PYT A;  3VTE A;  1W1L A;  3EJB B;  1DZN A;  2QPM A;  3AN1 A;  1T3Q C;  4JAY A;  2E3T A;  2VFU A;  3FW9 A;  1FO4 A;  1W1K A;  3GSY A;  3JS8 A;  1JRP A;  2VFT A;  3BW7 A;  1MBB A;  3D2H A;  1ZXI C;  2Y4G A;  1E8G A;  1MBT A;  4PVE A;  1WYG A;  2P3H A;  2PLS A;  3POP A;  2QKN A;  5FXE A;  1VAO A;  3ETR B;  2Y3R A;  2AXR A;  1N61 C;  4BBY A;  1DII A;  3DQ0 A;  2UUU A;  2MBR A;  3FW7 A;  1WVF A;  1N60 C;  5HHZ A;  3W8X A;  2W54 A;  1W1S A;  3AM9 A;  3S1F A;  1DIQ A;  2VFV A;  4PVJ A;  3LLB A;  3SR6 B;  4BC7 A;  4PWC A;  3PM9 A;  3RJ8 A;  4BCA A;  1I19 A;  1FIQ B;  4EC3 A;  5FXD A;  2Y08 A;  2IPI A;  3TSH A;  1W1Q A;  1W1O A;  2BVG A;  3NVZ B;  2P4P A; 
#chains in the Genus database with same CATH homology
 3LAE A;  1SB3 B;  4BC9 A;  5L6G A;  3S1D A;  1QLU A;  2VFR A;  5FXF A;  1V97 A;  5G5G B;  2PLI A;  1N5X A;  4O95 A;  3DED A;  2Q85 A;  1E0Y A;  3NVV B;  2O3G A;  2I0K A;  2W55 A;  5G5H B;  3D2J A;  3TSJ A;  2YVS A;  5AE2 A;  1UXY A;  2W3R A;  2P13 A;  5ADZ A;  3I99 A;  2W3S A;  1AHV A;  1QLT A;  2Q4W A;  5AE3 A;  2NQW A;  2UUV A;  2WDW A;  3RJA A;  5HQX A;  2VFS A;  2OAI A;  4MLA A;  5K8E A;  1AHU A;  2R2Z A;  3B9J B;  3EUB 3;  3HSU A;  2RK5 A;  1N63 C;  2BVH A;  3C0P A;  2EXR A;  5FXP A;  4DNS A;  4HG0 A;  1N5W C;  2BVF A;  2R8D A;  5I1W A;  5AWV A;  5D79 A;  5HMR A;  3FWA A;  1W1M A;  4PZF A;  1VDV A;  3TX1 A;  1FFV C;  1W1R A;  4PVH A;  1JRO A;  1ZR6 A;  3S1E A;  4XLO A;  1HSK A;  3FW8 A;  5AE1 A;  5L6F A;  2VAO A;  3NS1 B;  4PVK A;  4PWB A;  3W8W A;  4OAL A;  3HRD C;  1AHZ A;  2Y3S A;  4UD8 A;  3PQB A;  1W1J A;  1FFU C;  3D2D A;  3KJM A;  3AMZ A;  3NRZ B;  5I1V A;  1WVE A;  1F0X A;  1E8F A;  1E8H A;  3S1C A;  3NVY B;  4ML8 A;  1RM6 B;  1N62 C;  2GQU A;  4ZOH B;  3W8Z A;  3NVW B;  2GQT A;  4JB1 A;  4PYT A;  3VTE A;  1W1L A;  1DZN A;  2QPM A;  3AN1 A;  1T3Q C;  4JAY A;  2E3T A;  2VFU A;  3FW9 A;  1FO4 A;  1W1K A;  3GSY A;  3JS8 A;  1JRP A;  2VFT A;  3BW7 A;  1MBB A;  3D2H A;  1ZXI C;  2Y4G A;  1E8G A;  1MBT A;  4PVE A;  1WYG A;  2P3H A;  2PLS A;  3POP A;  2QKN A;  5FXE A;  1VAO A;  3ETR B;  2Y3R A;  2AXR A;  1N61 C;  4BBY A;  1DII A;  3DQ0 A;  2UUU A;  2MBR A;  3FW7 A;  1WVF A;  1N60 C;  5HHZ A;  3W8X A;  2W54 A;  1W1S A;  3AM9 A;  3S1F A;  1DIQ A;  2VFV A;  4PVJ A;  3LLB A;  3SR6 B;  4BC7 A;  4PWC A;  3PM9 A;  3RJ8 A;  4BCA A;  1I19 A;  1FIQ B;  4EC3 A;  5FXD A;  2Y08 A;  2IPI A;  3TSH A;  1W1Q A;  1W1O A;  2BVG A;  3NVZ B;  2P4P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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