1W1MA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: glu502gly mutant
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGGYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 172
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1mA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1mA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1mA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1mA03
3I99A 3AM9A 3NVYB 3NVWB 1W1KA 2PLIA 3D2DA 2GQTA 1FIQB 1N61C 1FFUC 1W1LA 3TX1A 3EUB3 2BVGA 3S1FA 1T3QC 4ZOHB 1ZR6A 2YVSA 3TSHA 5FXFA 2VAOA 2Q85A 4EC3A 3LLBA 4PWBA 1W1QA 1W1JA 3W8ZA 4MLAA 3D2HA 5D79A 1W1MA 3JS8A 2E3TA 2W55A 5G5GB 3ETRB 1E8FA 4BCAA 4JB1A 5HMRA 3LAEA 1N63C 5G5HB 2BVFA 4BBYA 2R2ZA 2GQUA 1MBTA 3S1CA 2QPMA 2VFTA 2QKNA 2PLSA 2AXRA 4XLOA 5HQXA 1UXYA 3TSJA 1W1SA 3SR6B 1DIIA 5FXDA 2NQWA 2P13A 4UD8A 2I0KA 2W3SA 3NVZB 1V97A 1WVFA 1F0XA 1WYGA 1E8HA 1HSKA 3DEDA 3W8XA 4PVKA 2O3GA 4OALA 2BVHA 4HG0A 4JAYA 2R8DA 2W3RA 5HHZA 1JRPA 4BC7A 1FO4A 1ZXIC 2OAIA 1W1OA 4BC9A 3AN1A 3NS1B 1N62C 2VFUA 1MBBA 3NRZB 1E8GA 3BW7A 1QLTA 3FWAA 1DZNA 4PYTA 2EXRA 4O95A 4PVJA 1E0YA 2VFSA 4ML8A 2W54A 1AHUA 4PVEA 2MBRA 2RK5A 3D2JA 3HRDC 3DQ0A 1N5WC 1SB3B 1W1RA 3KJMA 1DIQA 1AHVA 2Q4WA 3FW8A 3FW9A 2P3HA 3S1DA 1I19A 2VFVA 5AE1A 2P4PA 5FXPA 1FFVC 1N5XA 4PZFA 1QLUA 3VTEA 1AHZA 3W8WA 3FW7A 3S1EA 3PM9A 1VAOA 3B9JB 4DNSA 1N60C 1RM6B 1JROA 3NVVB 1VDVA 2VFRA 3AMZA 3C0PA 5AE3A 1WVEA 5AE2A 5ADZA 4PWCA 4PVHA 5FXEA 3GSYA
chains in the Genus database with same CATH superfamily
3I99A 2Y3SA 3AM9A 3NVYB 3NVWB 1W1KA 2PLIA 3D2DA 2GQTA 1FIQB 1N61C 1FFUC 1W1LA 3TX1A 3EUB3 2BVGA 3S1FA 1T3QC 5AWVA 4ZOHB 3EJBB 3RJ8A 1ZR6A 3HSUA 2YVSA 3TSHA 5FXFA 2VAOA 2Q85A 4EC3A 3LLBA 3EJEB 4PWBA 1W1QA 2Y08A 1W1JA 3W8ZA 3PQBA 4MLAA 3D2HA 5D79A 1W1MA 3JS8A 2E3TA 2W55A 5G5GB 3ETRB 1E8FA 4BCAA 4JB1A 5HMRA 3LAEA 1N63C 5G5HB 2BVFA 4BBYA 2R2ZA 2GQUA 1MBTA 2Y4GA 3S1CA 2QPMA 2VFTA 2QKNA 2PLSA 2AXRA 4XLOA 5HQXA 1UXYA 3TSJA 1W1SA 3SR6B 1DIIA 5FXDA 2NQWA 2P13A 4UD8A 2I0KA 2W3SA 3NVZB 5I1VA 1V97A 1WVFA 5L6FA 1F0XA 1WYGA 1E8HA 1HSKA 3DEDA 3W8XA 4PVKA 2O3GA 4OALA 2BVHA 4HG0A 4JAYA 2R8DA 2W3RA 5HHZA 1JRPA 4BC7A 1FO4A 1ZXIC 2OAIA 1W1OA 4BC9A 3AN1A 3NS1B 1N62C 2VFUA 1MBBA 2IPIA 3NRZB 5K8EA 5I1WA 1E8GA 3BW7A 1QLTA 3FWAA 1DZNA 4PYTA 2EXRA 3POPA 3EJDB 4O95A 2WDWA 4PVJA 1E0YA 2VFSA 4ML8A 2W54A 1AHUA 4PVEA 2MBRA 2Y3RA 2RK5A 3D2JA 3HRDC 3DQ0A 1N5WC 1SB3B 5L6GA 1W1RA 3KJMA 1DIQA 1AHVA 2Q4WA 3FW8A 3FW9A 2P3HA 3S1DA 1I19A 2UUUA 2VFVA 5AE1A 2P4PA 5FXPA 1FFVC 1N5XA 4PZFA 1QLUA 3VTEA 1AHZA 2UUVA 3W8WA 3FW7A 3S1EA 3PM9A 1VAOA 3B9JB 4DNSA 1N60C 1RM6B 1JROA 3NVVB 3RJAA 1VDVA 2VFRA 3AMZA 3C0PA 5AE3A 1WVEA 5AE2A 5ADZA 4PWCA 4PVHA 5FXEA 3GSYA
chains in the Genus database with same CATH topology
3I99A 2Y3SA 3AM9A 3NVYB 3NVWB 1W1KA 2PLIA 3D2DA 2GQTA 1FIQB 1N61C 1FFUC 1W1LA 3TX1A 3EUB3 2BVGA 3S1FA 1T3QC 5AWVA 4ZOHB 3RJ8A 1ZR6A 3HSUA 2YVSA 3TSHA 5FXFA 2VAOA 2Q85A 4EC3A 3LLBA 4PWBA 1W1QA 2Y08A 1W1JA 3W8ZA 3PQBA 4MLAA 3D2HA 5D79A 1W1MA 3JS8A 2E3TA 2W55A 5G5GB 3ETRB 1E8FA 4BCAA 4JB1A 5HMRA 3LAEA 1N63C 5G5HB 2BVFA 4BBYA 2R2ZA 2GQUA 1MBTA 2Y4GA 3S1CA 2QPMA 2VFTA 2QKNA 2PLSA 2AXRA 4XLOA 5HQXA 1UXYA 3TSJA 1W1SA 3SR6B 1DIIA 5FXDA 2NQWA 2P13A 4UD8A 2I0KA 2W3SA 3NVZB 5I1VA 1V97A 1WVFA 5L6FA 1F0XA 1WYGA 1E8HA 1HSKA 3DEDA 3W8XA 4PVKA 2O3GA 4OALA 2BVHA 4HG0A 4JAYA 2R8DA 2W3RA 5HHZA 1JRPA 4BC7A 1FO4A 1ZXIC 2OAIA 1W1OA 4BC9A 3AN1A 3NS1B 1N62C 2VFUA 1MBBA 2IPIA 3NRZB 5K8EA 5I1WA 1E8GA 3BW7A 1QLTA 3FWAA 1DZNA 4PYTA 2EXRA 3POPA 4O95A 2WDWA 4PVJA 1E0YA 2VFSA 4ML8A 2W54A 1AHUA 4PVEA 2MBRA 2Y3RA 2RK5A 3D2JA 3HRDC 3DQ0A 1N5WC 1SB3B 5L6GA 1W1RA 3KJMA 1DIQA 1AHVA 2Q4WA 3FW8A 3FW9A 2P3HA 3S1DA 1I19A 2UUUA 2VFVA 5AE1A 2P4PA 5FXPA 1FFVC 1N5XA 4PZFA 1QLUA 3VTEA 1AHZA 2UUVA 3W8WA 3FW7A 3S1EA 3PM9A 1VAOA 3B9JB 4DNSA 1N60C 1RM6B 1JROA 3NVVB 3RJAA 1VDVA 2VFRA 3AMZA 3C0PA 5AE3A 1WVEA 5AE2A 5ADZA 4PWCA 4PVHA 5FXEA 3GSYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I99 A;  3AM9 A;  3NVY B;  3NVW B;  1W1K A;  2PLI A;  3D2D A;  2GQT A;  1FIQ B;  1N61 C;  1FFU C;  1W1L A;  3TX1 A;  3EUB 3;  2BVG A;  3S1F A;  1T3Q C;  4ZOH B;  1ZR6 A;  2YVS A;  3TSH A;  5FXF A;  2VAO A;  2Q85 A;  4EC3 A;  3LLB A;  4PWB A;  1W1Q A;  1W1J A;  3W8Z A;  4MLA A;  3D2H A;  5D79 A;  1W1M A;  3JS8 A;  2E3T A;  2W55 A;  5G5G B;  3ETR B;  1E8F A;  4BCA A;  4JB1 A;  5HMR A;  3LAE A;  1N63 C;  5G5H B;  2BVF A;  4BBY A;  2R2Z A;  2GQU A;  1MBT A;  3S1C A;  2QPM A;  2VFT A;  2QKN A;  2PLS A;  2AXR A;  4XLO A;  5HQX A;  1UXY A;  3TSJ A;  1W1S A;  3SR6 B;  1DII A;  5FXD A;  2NQW A;  2P13 A;  4UD8 A;  2I0K A;  2W3S A;  3NVZ B;  1V97 A;  1WVF A;  1F0X A;  1WYG A;  1E8H A;  1HSK A;  3DED A;  3W8X A;  4PVK A;  2O3G A;  4OAL A;  2BVH A;  4HG0 A;  4JAY A;  2R8D A;  2W3R A;  5HHZ A;  1JRP A;  4BC7 A;  1FO4 A;  1ZXI C;  2OAI A;  1W1O A;  4BC9 A;  3AN1 A;  3NS1 B;  1N62 C;  2VFU A;  1MBB A;  3NRZ B;  1E8G A;  3BW7 A;  1QLT A;  3FWA A;  1DZN A;  4PYT A;  2EXR A;  4O95 A;  4PVJ A;  1E0Y A;  2VFS A;  4ML8 A;  2W54 A;  1AHU A;  4PVE A;  2MBR A;  2RK5 A;  3D2J A;  3HRD C;  3DQ0 A;  1N5W C;  1SB3 B;  1W1R A;  3KJM A;  1DIQ A;  1AHV A;  2Q4W A;  3FW8 A;  3FW9 A;  2P3H A;  3S1D A;  1I19 A;  2VFV A;  5AE1 A;  2P4P A;  5FXP A;  1FFV C;  1N5X A;  4PZF A;  1QLU A;  3VTE A;  1AHZ A;  3W8W A;  3FW7 A;  3S1E A;  3PM9 A;  1VAO A;  3B9J B;  4DNS A;  1N60 C;  1RM6 B;  1JRO A;  3NVV B;  1VDV A;  2VFR A;  3AMZ A;  3C0P A;  5AE3 A;  1WVE A;  5AE2 A;  5ADZ A;  4PWC A;  4PVH A;  5FXE A;  3GSY A; 
#chains in the Genus database with same CATH topology
 3I99 A;  2Y3S A;  3AM9 A;  3NVY B;  3NVW B;  1W1K A;  2PLI A;  3D2D A;  2GQT A;  1FIQ B;  1N61 C;  1FFU C;  1W1L A;  3TX1 A;  3EUB 3;  2BVG A;  3S1F A;  1T3Q C;  5AWV A;  4ZOH B;  3EJB B;  3RJ8 A;  1ZR6 A;  3HSU A;  2YVS A;  3TSH A;  5FXF A;  2VAO A;  2Q85 A;  4EC3 A;  3LLB A;  3EJE B;  4PWB A;  1W1Q A;  2Y08 A;  1W1J A;  3W8Z A;  3PQB A;  4MLA A;  3D2H A;  5D79 A;  1W1M A;  3JS8 A;  2E3T A;  2W55 A;  5G5G B;  3ETR B;  1E8F A;  4BCA A;  4JB1 A;  5HMR A;  3LAE A;  1N63 C;  5G5H B;  2BVF A;  4BBY A;  2R2Z A;  2GQU A;  1MBT A;  2Y4G A;  3S1C A;  2QPM A;  2VFT A;  2QKN A;  2PLS A;  2AXR A;  4XLO A;  5HQX A;  1UXY A;  3TSJ A;  1W1S A;  3SR6 B;  1DII A;  5FXD A;  2NQW A;  2P13 A;  4UD8 A;  2I0K A;  2W3S A;  3NVZ B;  5I1V A;  1V97 A;  1WVF A;  5L6F A;  1F0X A;  1WYG A;  1E8H A;  1HSK A;  3DED A;  3W8X A;  4PVK A;  2O3G A;  4OAL A;  2BVH A;  4HG0 A;  4JAY A;  2R8D A;  2W3R A;  5HHZ A;  1JRP A;  4BC7 A;  1FO4 A;  1ZXI C;  2OAI A;  1W1O A;  4BC9 A;  3AN1 A;  3NS1 B;  1N62 C;  2VFU A;  1MBB A;  2IPI A;  3NRZ B;  5K8E A;  5I1W A;  1E8G A;  3BW7 A;  1QLT A;  3FWA A;  1DZN A;  4PYT A;  2EXR A;  3POP A;  3EJD B;  4O95 A;  2WDW A;  4PVJ A;  1E0Y A;  2VFS A;  4ML8 A;  2W54 A;  1AHU A;  4PVE A;  2MBR A;  2Y3R A;  2RK5 A;  3D2J A;  3HRD C;  3DQ0 A;  1N5W C;  1SB3 B;  5L6G A;  1W1R A;  3KJM A;  1DIQ A;  1AHV A;  2Q4W A;  3FW8 A;  3FW9 A;  2P3H A;  3S1D A;  1I19 A;  2UUU A;  2VFV A;  5AE1 A;  2P4P A;  5FXP A;  1FFV C;  1N5X A;  4PZF A;  1QLU A;  3VTE A;  1AHZ A;  2UUV A;  3W8W A;  3FW7 A;  3S1E A;  3PM9 A;  1VAO A;  3B9J B;  4DNS A;  1N60 C;  1RM6 B;  1JRO A;  3NVV B;  3RJA A;  1VDV A;  2VFR A;  3AMZ A;  3C0P A;  5AE3 A;  1WVE A;  5AE2 A;  5ADZ A;  4PWC A;  4PVH A;  5FXE A;  3GSY A; 
#chains in the Genus database with same CATH homology
 3I99 A;  2Y3S A;  3AM9 A;  3NVY B;  3NVW B;  1W1K A;  2PLI A;  3D2D A;  2GQT A;  1FIQ B;  1N61 C;  1FFU C;  1W1L A;  3TX1 A;  3EUB 3;  2BVG A;  3S1F A;  1T3Q C;  5AWV A;  4ZOH B;  3RJ8 A;  1ZR6 A;  3HSU A;  2YVS A;  3TSH A;  5FXF A;  2VAO A;  2Q85 A;  4EC3 A;  3LLB A;  4PWB A;  1W1Q A;  2Y08 A;  1W1J A;  3W8Z A;  3PQB A;  4MLA A;  3D2H A;  5D79 A;  1W1M A;  3JS8 A;  2E3T A;  2W55 A;  5G5G B;  3ETR B;  1E8F A;  4BCA A;  4JB1 A;  5HMR A;  3LAE A;  1N63 C;  5G5H B;  2BVF A;  4BBY A;  2R2Z A;  2GQU A;  1MBT A;  2Y4G A;  3S1C A;  2QPM A;  2VFT A;  2QKN A;  2PLS A;  2AXR A;  4XLO A;  5HQX A;  1UXY A;  3TSJ A;  1W1S A;  3SR6 B;  1DII A;  5FXD A;  2NQW A;  2P13 A;  4UD8 A;  2I0K A;  2W3S A;  3NVZ B;  5I1V A;  1V97 A;  1WVF A;  5L6F A;  1F0X A;  1WYG A;  1E8H A;  1HSK A;  3DED A;  3W8X A;  4PVK A;  2O3G A;  4OAL A;  2BVH A;  4HG0 A;  4JAY A;  2R8D A;  2W3R A;  5HHZ A;  1JRP A;  4BC7 A;  1FO4 A;  1ZXI C;  2OAI A;  1W1O A;  4BC9 A;  3AN1 A;  3NS1 B;  1N62 C;  2VFU A;  1MBB A;  2IPI A;  3NRZ B;  5K8E A;  5I1W A;  1E8G A;  3BW7 A;  1QLT A;  3FWA A;  1DZN A;  4PYT A;  2EXR A;  3POP A;  4O95 A;  2WDW A;  4PVJ A;  1E0Y A;  2VFS A;  4ML8 A;  2W54 A;  1AHU A;  4PVE A;  2MBR A;  2Y3R A;  2RK5 A;  3D2J A;  3HRD C;  3DQ0 A;  1N5W C;  1SB3 B;  5L6G A;  1W1R A;  3KJM A;  1DIQ A;  1AHV A;  2Q4W A;  3FW8 A;  3FW9 A;  2P3H A;  3S1D A;  1I19 A;  2UUU A;  2VFV A;  5AE1 A;  2P4P A;  5FXP A;  1FFV C;  1N5X A;  4PZF A;  1QLU A;  3VTE A;  1AHZ A;  2UUV A;  3W8W A;  3FW7 A;  3S1E A;  3PM9 A;  1VAO A;  3B9J B;  4DNS A;  1N60 C;  1RM6 B;  1JRO A;  3NVV B;  3RJA A;  1VDV A;  2VFR A;  3AMZ A;  3C0P A;  5AE3 A;  1WVE A;  5AE2 A;  5ADZ A;  4PWC A;  4PVH A;  5FXE A;  3GSY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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