1W1MA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: glu502gly mutant
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
550
Chain Sequence
b'EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGGYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 172
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1mA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1mA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1mA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1mA03
1E8GA 4JB1A 4JAYA 2MBRA 1E0YA 3GSYA 3S1DA 1AHVA 1W1JA 1VDVA 5AE2A 1V97A 1E8FA 1MBBA 3S1EA 1AHUA 1WVFA 3NVZB 4O95A 2OAIA 4UD8A 1W1MA 2PLIA 1N60C 2O3GA 2BVHA 2Q85A 3D2JA 4MLAA 4PWCA 3EUB3 3ETRB 4DNSA 2VFUA 4BBYA 3TSJA 2P4PA 3W8ZA 5G5GB 1FIQB 2PLSA 3NVYB 3PM9A 1N5WC 2VFVA 2YVSA 5FXEA 1UXYA 1T3QC 2W3SA 5FXPA 1AHZA 2W54A 1SB3B 1N63C 4EC3A 1W1LA 3C0PA 2BVFA 5FXDA 2E3TA 4BC9A 4PVJA 2GQTA 1QLUA 3JS8A 3DEDA 4HG0A 1W1QA 4XLOA 3D2HA 4PVEA 2VFTA 3S1CA 1FFUC 1RM6B 5ADZA 3LLBA 1F0XA 2Q4WA 2EXRA 2P3HA 3VTEA 2P13A 1W1KA 1DIIA 3FW7A 1I19A 3D2DA 4ZOHB 3NVWB 3HRDC 1N61C 1WVEA 1QLTA 3BW7A 1N62C 1E8HA 3I99A 5FXFA 2VFRA 1HSKA 3LAEA 1FFVC 1W1OA 4BCAA 3TX1A 4PYTA 3W8XA 3FWAA 1N5XA 2GQUA 2QPMA 1DZNA 3FW8A 3S1FA 3NVVB 3FW9A 3AM9A 4BC7A 1DIQA 5AE1A 1WYGA 2QKNA 5HMRA 1FO4A 1W1SA 3KJMA 2RK5A 2AXRA 4ML8A 1JRPA 2W3RA 4PVHA 5HHZA 2I0KA 3B9JB 1ZR6A 3W8WA 2R2ZA 2VAOA 4PWBA 5AE3A 3DQ0A 5G5HB 2NQWA 1MBTA 1ZXIC 2W55A 5HQXA 1W1RA 4PZFA 3AN1A 3SR6B 2BVGA 2R8DA 3NRZB 1VAOA 3NS1B 3TSHA 4PVKA 4OALA 1JROA 2VFSA 5D79A 3AMZA
chains in the Genus database with same CATH superfamily
1E8GA 4JB1A 4JAYA 3PQBA 2MBRA 1E0YA 3GSYA 3S1DA 1AHVA 1W1JA 1VDVA 5AE2A 1V97A 1E8FA 1MBBA 3EJBB 3S1EA 1AHUA 1WVFA 3NVZB 4O95A 2OAIA 4UD8A 1W1MA 2PLIA 1N60C 2O3GA 2BVHA 2Q85A 3D2JA 4MLAA 4PWCA 3EUB3 3ETRB 4DNSA 2VFUA 4BBYA 3TSJA 2P4PA 3W8ZA 5G5GB 1FIQB 2PLSA 3NVYB 3PM9A 1N5WC 2VFVA 2YVSA 5FXEA 1UXYA 1T3QC 2W3SA 5FXPA 1AHZA 2IPIA 2W54A 1SB3B 1N63C 4EC3A 1W1LA 3C0PA 3EJDB 2BVFA 5FXDA 2E3TA 4BC9A 4PVJA 2GQTA 1QLUA 3JS8A 2Y3SA 3DEDA 1W1QA 4XLOA 3D2HA 4HG0A 4PVEA 2WDWA 2VFTA 3S1CA 1FFUC 1RM6B 5ADZA 3LLBA 5K8EA 1F0XA 2Q4WA 2EXRA 2P3HA 3VTEA 2P13A 2UUVA 1W1KA 3RJAA 1DIIA 5I1WA 3FW7A 1I19A 5AWVA 3D2DA 4ZOHB 3NVWB 3HRDC 5I1VA 1N61C 3HSUA 1WVEA 3EJEB 1QLTA 3BW7A 1N62C 1E8HA 3I99A 5FXFA 3POPA 2VFRA 1HSKA 3LAEA 1FFVC 1W1OA 4BCAA 3TX1A 4PYTA 2Y08A 3W8XA 3FWAA 2Y3RA 1N5XA 2GQUA 2QPMA 1DZNA 3FW8A 3NVVB 3S1FA 3FW9A 3AM9A 4BC7A 1DIQA 5AE1A 1WYGA 2QKNA 2UUUA 5HMRA 1FO4A 1W1SA 3KJMA 2RK5A 2AXRA 4ML8A 1JRPA 2W3RA 4PVHA 5HHZA 2I0KA 3B9JB 3RJ8A 5L6FA 1ZR6A 3W8WA 2R2ZA 2VAOA 4PWBA 5AE3A 3DQ0A 5G5HB 2NQWA 1MBTA 1ZXIC 2W55A 5HQXA 5L6GA 2Y4GA 1W1RA 4PZFA 3AN1A 3SR6B 2BVGA 2R8DA 3NRZB 1VAOA 3NS1B 3TSHA 4PVKA 4OALA 1JROA 2VFSA 5D79A 3AMZA
chains in the Genus database with same CATH topology
1E8GA 4JB1A 4JAYA 3PQBA 2MBRA 1E0YA 3GSYA 3S1DA 1AHVA 1W1JA 1VDVA 5AE2A 1V97A 1E8FA 1MBBA 3S1EA 1AHUA 1WVFA 3NVZB 4O95A 2OAIA 4UD8A 1W1MA 2PLIA 1N60C 2O3GA 2BVHA 2Q85A 3D2JA 4MLAA 4PWCA 3EUB3 3ETRB 4DNSA 2VFUA 4BBYA 3TSJA 2P4PA 3W8ZA 5G5GB 1FIQB 2PLSA 3NVYB 3PM9A 1N5WC 2VFVA 2YVSA 5FXEA 1UXYA 1T3QC 2W3SA 5FXPA 1AHZA 2IPIA 2W54A 1SB3B 1N63C 4EC3A 1W1LA 3C0PA 2BVFA 5FXDA 2E3TA 4BC9A 4PVJA 2GQTA 1QLUA 3JS8A 2Y3SA 3DEDA 1W1QA 4XLOA 3D2HA 4HG0A 4PVEA 2WDWA 2VFTA 3S1CA 1FFUC 1RM6B 5ADZA 3LLBA 5K8EA 1F0XA 2Q4WA 2EXRA 2P3HA 3VTEA 2P13A 2UUVA 1W1KA 3RJAA 1DIIA 5I1WA 3FW7A 1I19A 5AWVA 3D2DA 4ZOHB 3NVWB 3HRDC 5I1VA 1N61C 3HSUA 1WVEA 1QLTA 3BW7A 1N62C 1E8HA 3I99A 5FXFA 3POPA 2VFRA 1HSKA 3LAEA 1FFVC 1W1OA 4BCAA 3TX1A 4PYTA 2Y08A 3W8XA 3FWAA 2Y3RA 1N5XA 2GQUA 2QPMA 1DZNA 3FW8A 3S1FA 3NVVB 3FW9A 3AM9A 4BC7A 1DIQA 5AE1A 1WYGA 2QKNA 2UUUA 5HMRA 1FO4A 1W1SA 3KJMA 2RK5A 2AXRA 4ML8A 1JRPA 2W3RA 4PVHA 5HHZA 2I0KA 3B9JB 3RJ8A 5L6FA 1ZR6A 3W8WA 2R2ZA 2VAOA 4PWBA 5AE3A 3DQ0A 5G5HB 2NQWA 1MBTA 1ZXIC 2W55A 5HQXA 5L6GA 2Y4GA 1W1RA 4PZFA 3AN1A 3SR6B 2BVGA 2R8DA 3NRZB 1VAOA 3NS1B 3TSHA 4PVKA 4OALA 1JROA 2VFSA 5D79A 3AMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E8G A;  4JB1 A;  4JAY A;  2MBR A;  1E0Y A;  3GSY A;  3S1D A;  1AHV A;  1W1J A;  1VDV A;  5AE2 A;  1V97 A;  1E8F A;  1MBB A;  3S1E A;  1AHU A;  1WVF A;  3NVZ B;  4O95 A;  2OAI A;  4UD8 A;  1W1M A;  2PLI A;  1N60 C;  2O3G A;  2BVH A;  2Q85 A;  3D2J A;  4MLA A;  4PWC A;  3EUB 3;  3ETR B;  4DNS A;  2VFU A;  4BBY A;  3TSJ A;  2P4P A;  3W8Z A;  5G5G B;  1FIQ B;  2PLS A;  3NVY B;  3PM9 A;  1N5W C;  2VFV A;  2YVS A;  5FXE A;  1UXY A;  1T3Q C;  2W3S A;  5FXP A;  1AHZ A;  2W54 A;  1SB3 B;  1N63 C;  4EC3 A;  1W1L A;  3C0P A;  2BVF A;  5FXD A;  2E3T A;  4BC9 A;  4PVJ A;  2GQT A;  1QLU A;  3JS8 A;  3DED A;  4HG0 A;  1W1Q A;  4XLO A;  3D2H A;  4PVE A;  2VFT A;  3S1C A;  1FFU C;  1RM6 B;  5ADZ A;  3LLB A;  1F0X A;  2Q4W A;  2EXR A;  2P3H A;  3VTE A;  2P13 A;  1W1K A;  1DII A;  3FW7 A;  1I19 A;  3D2D A;  4ZOH B;  3NVW B;  3HRD C;  1N61 C;  1WVE A;  1QLT A;  3BW7 A;  1N62 C;  1E8H A;  3I99 A;  5FXF A;  2VFR A;  1HSK A;  3LAE A;  1FFV C;  1W1O A;  4BCA A;  3TX1 A;  4PYT A;  3W8X A;  3FWA A;  1N5X A;  2GQU A;  2QPM A;  1DZN A;  3FW8 A;  3S1F A;  3NVV B;  3FW9 A;  3AM9 A;  4BC7 A;  1DIQ A;  5AE1 A;  1WYG A;  2QKN A;  5HMR A;  1FO4 A;  1W1S A;  3KJM A;  2RK5 A;  2AXR A;  4ML8 A;  1JRP A;  2W3R A;  4PVH A;  5HHZ A;  2I0K A;  3B9J B;  1ZR6 A;  3W8W A;  2R2Z A;  2VAO A;  4PWB A;  5AE3 A;  3DQ0 A;  5G5H B;  2NQW A;  1MBT A;  1ZXI C;  2W55 A;  5HQX A;  1W1R A;  4PZF A;  3AN1 A;  3SR6 B;  2BVG A;  2R8D A;  3NRZ B;  1VAO A;  3NS1 B;  3TSH A;  4PVK A;  4OAL A;  1JRO A;  2VFS A;  5D79 A;  3AMZ A; 
#chains in the Genus database with same CATH topology
 1E8G A;  4JB1 A;  4JAY A;  3PQB A;  2MBR A;  1E0Y A;  3GSY A;  3S1D A;  1AHV A;  1W1J A;  1VDV A;  5AE2 A;  1V97 A;  1E8F A;  1MBB A;  3EJB B;  3S1E A;  1AHU A;  1WVF A;  3NVZ B;  4O95 A;  2OAI A;  4UD8 A;  1W1M A;  2PLI A;  1N60 C;  2O3G A;  2BVH A;  2Q85 A;  3D2J A;  4MLA A;  4PWC A;  3EUB 3;  3ETR B;  4DNS A;  2VFU A;  4BBY A;  3TSJ A;  2P4P A;  3W8Z A;  5G5G B;  1FIQ B;  2PLS A;  3NVY B;  3PM9 A;  1N5W C;  2VFV A;  2YVS A;  5FXE A;  1UXY A;  1T3Q C;  2W3S A;  5FXP A;  1AHZ A;  2IPI A;  2W54 A;  1SB3 B;  1N63 C;  4EC3 A;  1W1L A;  3C0P A;  3EJD B;  2BVF A;  5FXD A;  2E3T A;  4BC9 A;  4PVJ A;  2GQT A;  1QLU A;  3JS8 A;  2Y3S A;  3DED A;  1W1Q A;  4XLO A;  3D2H A;  4HG0 A;  4PVE A;  2WDW A;  2VFT A;  3S1C A;  1FFU C;  1RM6 B;  5ADZ A;  3LLB A;  5K8E A;  1F0X A;  2Q4W A;  2EXR A;  2P3H A;  3VTE A;  2P13 A;  2UUV A;  1W1K A;  3RJA A;  1DII A;  5I1W A;  3FW7 A;  1I19 A;  5AWV A;  3D2D A;  4ZOH B;  3NVW B;  3HRD C;  5I1V A;  1N61 C;  3HSU A;  1WVE A;  3EJE B;  1QLT A;  3BW7 A;  1N62 C;  1E8H A;  3I99 A;  5FXF A;  3POP A;  2VFR A;  1HSK A;  3LAE A;  1FFV C;  1W1O A;  4BCA A;  3TX1 A;  4PYT A;  2Y08 A;  3W8X A;  3FWA A;  2Y3R A;  1N5X A;  2GQU A;  2QPM A;  1DZN A;  3FW8 A;  3NVV B;  3S1F A;  3FW9 A;  3AM9 A;  4BC7 A;  1DIQ A;  5AE1 A;  1WYG A;  2QKN A;  2UUU A;  5HMR A;  1FO4 A;  1W1S A;  3KJM A;  2RK5 A;  2AXR A;  4ML8 A;  1JRP A;  2W3R A;  4PVH A;  5HHZ A;  2I0K A;  3B9J B;  3RJ8 A;  5L6F A;  1ZR6 A;  3W8W A;  2R2Z A;  2VAO A;  4PWB A;  5AE3 A;  3DQ0 A;  5G5H B;  2NQW A;  1MBT A;  1ZXI C;  2W55 A;  5HQX A;  5L6G A;  2Y4G A;  1W1R A;  4PZF A;  3AN1 A;  3SR6 B;  2BVG A;  2R8D A;  3NRZ B;  1VAO A;  3NS1 B;  3TSH A;  4PVK A;  4OAL A;  1JRO A;  2VFS A;  5D79 A;  3AMZ A; 
#chains in the Genus database with same CATH homology
 1E8G A;  4JB1 A;  4JAY A;  3PQB A;  2MBR A;  1E0Y A;  3GSY A;  3S1D A;  1AHV A;  1W1J A;  1VDV A;  5AE2 A;  1V97 A;  1E8F A;  1MBB A;  3S1E A;  1AHU A;  1WVF A;  3NVZ B;  4O95 A;  2OAI A;  4UD8 A;  1W1M A;  2PLI A;  1N60 C;  2O3G A;  2BVH A;  2Q85 A;  3D2J A;  4MLA A;  4PWC A;  3EUB 3;  3ETR B;  4DNS A;  2VFU A;  4BBY A;  3TSJ A;  2P4P A;  3W8Z A;  5G5G B;  1FIQ B;  2PLS A;  3NVY B;  3PM9 A;  1N5W C;  2VFV A;  2YVS A;  5FXE A;  1UXY A;  1T3Q C;  2W3S A;  5FXP A;  1AHZ A;  2IPI A;  2W54 A;  1SB3 B;  1N63 C;  4EC3 A;  1W1L A;  3C0P A;  2BVF A;  5FXD A;  2E3T A;  4BC9 A;  4PVJ A;  2GQT A;  1QLU A;  3JS8 A;  2Y3S A;  3DED A;  1W1Q A;  4XLO A;  3D2H A;  4HG0 A;  4PVE A;  2WDW A;  2VFT A;  3S1C A;  1FFU C;  1RM6 B;  5ADZ A;  3LLB A;  5K8E A;  1F0X A;  2Q4W A;  2EXR A;  2P3H A;  3VTE A;  2P13 A;  2UUV A;  1W1K A;  3RJA A;  1DII A;  5I1W A;  3FW7 A;  1I19 A;  5AWV A;  3D2D A;  4ZOH B;  3NVW B;  3HRD C;  5I1V A;  1N61 C;  3HSU A;  1WVE A;  1QLT A;  3BW7 A;  1N62 C;  1E8H A;  3I99 A;  5FXF A;  3POP A;  2VFR A;  1HSK A;  3LAE A;  1FFV C;  1W1O A;  4BCA A;  3TX1 A;  4PYT A;  2Y08 A;  3W8X A;  3FWA A;  2Y3R A;  1N5X A;  2GQU A;  2QPM A;  1DZN A;  3FW8 A;  3S1F A;  3NVV B;  3FW9 A;  3AM9 A;  4BC7 A;  1DIQ A;  5AE1 A;  1WYG A;  2QKN A;  2UUU A;  5HMR A;  1FO4 A;  1W1S A;  3KJM A;  2RK5 A;  2AXR A;  4ML8 A;  1JRP A;  2W3R A;  4PVH A;  5HHZ A;  2I0K A;  3B9J B;  3RJ8 A;  5L6F A;  1ZR6 A;  3W8W A;  2R2Z A;  2VAO A;  4PWB A;  5AE3 A;  3DQ0 A;  5G5H B;  2NQW A;  1MBT A;  1ZXI C;  2W55 A;  5HQX A;  5L6G A;  2Y4G A;  1W1R A;  4PZF A;  3AN1 A;  3SR6 B;  2BVG A;  2R8D A;  3NRZ B;  1VAO A;  3NS1 B;  3TSH A;  4PVK A;  4OAL A;  1JRO A;  2VFS A;  5D79 A;  3AMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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