1W1MA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: glu502gly mutant
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGGYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 172
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1mA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1mA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1mA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1mA03
1AHVA 5FXEA 4PWCA 3AM9A 1W1KA 1FIQB 1W1SA 5G5HB 1ZXIC 1F0XA 2W55A 2GQUA 1V97A 3AN1A 3TSHA 2PLSA 3FW9A 4PVJA 3W8ZA 4UD8A 4MLAA 5FXPA 1E8GA 5HHZA 1UXYA 5G5GB 5HQXA 1FFUC 3D2DA 2BVGA 3D2HA 1N62C 3NVVB 1N60C 2GQTA 3NS1B 3FW8A 2RK5A 2I0KA 2O3GA 1JROA 3S1DA 3DQ0A 1WVFA 1W1LA 4BBYA 2E3TA 3NVZB 5HMRA 4BCAA 3VTEA 5FXDA 2VFUA 3JS8A 1W1JA 1W1RA 3BW7A 4PZFA 4DNSA 4BC9A 4PVHA 3EUB3 3W8XA 1W1OA 3HRDC 3FWAA 1E8HA 1DIQA 3LLBA 3FW7A 1FO4A 3D2JA 4HG0A 1QLUA 3TX1A 1JRPA 3NVYB 5ADZA 1WYGA 1RM6B 4ML8A 1SB3B 1T3QC 1QLTA 5FXFA 1N5WC 2R8DA 2NQWA 1DIIA 4OALA 2Q4WA 2VAOA 2Q85A 3AMZA 1N5XA 3NRZB 2W3RA 2BVHA 2BVFA 2VFRA 3PM9A 1E0YA 1N61C 5AE3A 1FFVC 3SR6B 2EXRA 2W3SA 1AHUA 1MBBA 1MBTA 2VFTA 4JB1A 5AE2A 4JAYA 4XLOA 4EC3A 3S1CA 2P3HA 4ZOHB 4PVEA 2W54A 4PWBA 1VAOA 3S1FA 1HSKA 2P13A 2OAIA 2P4PA 2VFVA 3KJMA 3C0PA 2YVSA 2PLIA 1ZR6A 1DZNA 3S1EA 4PVKA 3TSJA 1N63C 2AXRA 1VDVA 4O95A 3B9JB 5D79A 2VFSA 1AHZA 3DEDA 3GSYA 2R2ZA 4PYTA 3LAEA 3NVWB 3I99A 1I19A 3ETRB 1WVEA 3W8WA 2QKNA 1W1QA 4BC7A 2QPMA 5AE1A 2MBRA 1W1MA 1E8FA
chains in the Genus database with same CATH superfamily
1AHVA 5FXEA 4PWCA 3AM9A 1W1KA 1FIQB 1W1SA 5G5HB 1ZXIC 1F0XA 2W55A 5L6GA 2GQUA 2Y4GA 3RJ8A 2UUUA 1V97A 3AN1A 3HSUA 3TSHA 2PLSA 3FW9A 4PVJA 3W8ZA 4UD8A 4MLAA 5FXPA 1E8GA 5HHZA 1UXYA 5G5GB 5HQXA 1FFUC 3D2DA 2BVGA 3EJEB 2IPIA 3D2HA 1N62C 3NVVB 1N60C 2GQTA 3NS1B 3FW8A 2RK5A 2I0KA 2O3GA 1JROA 3S1DA 3DQ0A 1WVFA 1W1LA 4BBYA 2E3TA 3NVZB 5HMRA 4BCAA 3VTEA 5FXDA 2VFUA 3JS8A 1W1JA 1W1RA 3BW7A 4PZFA 4DNSA 4BC9A 4PVHA 3EUB3 3W8XA 3EJBB 1W1OA 3HRDC 3FWAA 1E8HA 1DIQA 3LLBA 3FW7A 1FO4A 3D2JA 4HG0A 1QLUA 3TX1A 1JRPA 3NVYB 5ADZA 1WYGA 1RM6B 5AWVA 4ML8A 1SB3B 1T3QC 1QLTA 5FXFA 1N5WC 2R8DA 2NQWA 1DIIA 5L6FA 4OALA 2Q4WA 2VAOA 2Q85A 3AMZA 1N5XA 3NRZB 2W3RA 2BVHA 2WDWA 5K8EA 2BVFA 2VFRA 3PM9A 1E0YA 1N61C 5AE3A 1FFVC 3SR6B 2EXRA 2W3SA 1AHUA 1MBBA 1MBTA 2VFTA 4JB1A 5AE2A 4JAYA 4XLOA 4EC3A 3S1CA 2P3HA 2Y3SA 5I1VA 4ZOHB 3EJDB 4PVEA 2W54A 4PWBA 1VAOA 3S1FA 2Y3RA 1HSKA 2P13A 2OAIA 2P4PA 2VFVA 3KJMA 3C0PA 2YVSA 2PLIA 3POPA 1ZR6A 1DZNA 2UUVA 3S1EA 4PVKA 3PQBA 3TSJA 1N63C 2AXRA 1VDVA 4O95A 3B9JB 5D79A 2VFSA 1AHZA 3DEDA 3GSYA 2R2ZA 4PYTA 3RJAA 3NVWB 2Y08A 3LAEA 3I99A 1I19A 3ETRB 1WVEA 5I1WA 3W8WA 2QKNA 1W1QA 4BC7A 2QPMA 5AE1A 2MBRA 1W1MA 1E8FA
chains in the Genus database with same CATH topology
1AHVA 5FXEA 4PWCA 3AM9A 1W1KA 1FIQB 1W1SA 5G5HB 1ZXIC 1F0XA 2W55A 5L6GA 2GQUA 2Y4GA 3RJ8A 2UUUA 1V97A 3AN1A 3HSUA 3TSHA 2PLSA 3FW9A 4PVJA 3W8ZA 4UD8A 4MLAA 5FXPA 1E8GA 5HHZA 1UXYA 5G5GB 5HQXA 1FFUC 3D2DA 2BVGA 2IPIA 3D2HA 1N62C 3NVVB 1N60C 2GQTA 3NS1B 3FW8A 2RK5A 2I0KA 2O3GA 1JROA 3S1DA 3DQ0A 1WVFA 1W1LA 4BBYA 2E3TA 3NVZB 5HMRA 4BCAA 3VTEA 5FXDA 2VFUA 3JS8A 1W1JA 1W1RA 3BW7A 4PZFA 4DNSA 4BC9A 4PVHA 3EUB3 3W8XA 1W1OA 3HRDC 3FWAA 1E8HA 1DIQA 3LLBA 3FW7A 1FO4A 3D2JA 4HG0A 1QLUA 3TX1A 1JRPA 3NVYB 5ADZA 1WYGA 1RM6B 5AWVA 4ML8A 1SB3B 1T3QC 1QLTA 5FXFA 1N5WC 2R8DA 2NQWA 1DIIA 5L6FA 4OALA 2Q4WA 2VAOA 2Q85A 3AMZA 1N5XA 3NRZB 2W3RA 2BVHA 2WDWA 5K8EA 2BVFA 2VFRA 3PM9A 1E0YA 1N61C 5AE3A 1FFVC 3SR6B 2EXRA 2W3SA 1AHUA 1MBBA 1MBTA 2VFTA 4JB1A 5AE2A 4JAYA 4XLOA 4EC3A 3S1CA 2P3HA 2Y3SA 5I1VA 4ZOHB 4PVEA 2W54A 4PWBA 1VAOA 3S1FA 2Y3RA 1HSKA 2P13A 2OAIA 2P4PA 2VFVA 3KJMA 3C0PA 2YVSA 2PLIA 3POPA 1ZR6A 1DZNA 2UUVA 3S1EA 4PVKA 3PQBA 3TSJA 1N63C 2AXRA 1VDVA 4O95A 3B9JB 5D79A 2VFSA 1AHZA 3DEDA 3GSYA 2R2ZA 4PYTA 3RJAA 2Y08A 3LAEA 3NVWB 3I99A 1I19A 3ETRB 1WVEA 5I1WA 3W8WA 2QKNA 1W1QA 4BC7A 2QPMA 5AE1A 2MBRA 1W1MA 1E8FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AHV A;  5FXE A;  4PWC A;  3AM9 A;  1W1K A;  1FIQ B;  1W1S A;  5G5H B;  1ZXI C;  1F0X A;  2W55 A;  2GQU A;  1V97 A;  3AN1 A;  3TSH A;  2PLS A;  3FW9 A;  4PVJ A;  3W8Z A;  4UD8 A;  4MLA A;  5FXP A;  1E8G A;  5HHZ A;  1UXY A;  5G5G B;  5HQX A;  1FFU C;  3D2D A;  2BVG A;  3D2H A;  1N62 C;  3NVV B;  1N60 C;  2GQT A;  3NS1 B;  3FW8 A;  2RK5 A;  2I0K A;  2O3G A;  1JRO A;  3S1D A;  3DQ0 A;  1WVF A;  1W1L A;  4BBY A;  2E3T A;  3NVZ B;  5HMR A;  4BCA A;  3VTE A;  5FXD A;  2VFU A;  3JS8 A;  1W1J A;  1W1R A;  3BW7 A;  4PZF A;  4DNS A;  4BC9 A;  4PVH A;  3EUB 3;  3W8X A;  1W1O A;  3HRD C;  3FWA A;  1E8H A;  1DIQ A;  3LLB A;  3FW7 A;  1FO4 A;  3D2J A;  4HG0 A;  1QLU A;  3TX1 A;  1JRP A;  3NVY B;  5ADZ A;  1WYG A;  1RM6 B;  4ML8 A;  1SB3 B;  1T3Q C;  1QLT A;  5FXF A;  1N5W C;  2R8D A;  2NQW A;  1DII A;  4OAL A;  2Q4W A;  2VAO A;  2Q85 A;  3AMZ A;  1N5X A;  3NRZ B;  2W3R A;  2BVH A;  2BVF A;  2VFR A;  3PM9 A;  1E0Y A;  1N61 C;  5AE3 A;  1FFV C;  3SR6 B;  2EXR A;  2W3S A;  1AHU A;  1MBB A;  1MBT A;  2VFT A;  4JB1 A;  5AE2 A;  4JAY A;  4XLO A;  4EC3 A;  3S1C A;  2P3H A;  4ZOH B;  4PVE A;  2W54 A;  4PWB A;  1VAO A;  3S1F A;  1HSK A;  2P13 A;  2OAI A;  2P4P A;  2VFV A;  3KJM A;  3C0P A;  2YVS A;  2PLI A;  1ZR6 A;  1DZN A;  3S1E A;  4PVK A;  3TSJ A;  1N63 C;  2AXR A;  1VDV A;  4O95 A;  3B9J B;  5D79 A;  2VFS A;  1AHZ A;  3DED A;  3GSY A;  2R2Z A;  4PYT A;  3LAE A;  3NVW B;  3I99 A;  1I19 A;  3ETR B;  1WVE A;  3W8W A;  2QKN A;  1W1Q A;  4BC7 A;  2QPM A;  5AE1 A;  2MBR A;  1W1M A;  1E8F A; 
#chains in the Genus database with same CATH topology
 1AHV A;  5FXE A;  4PWC A;  3AM9 A;  1W1K A;  1FIQ B;  1W1S A;  5G5H B;  1ZXI C;  1F0X A;  2W55 A;  5L6G A;  2GQU A;  2Y4G A;  3RJ8 A;  2UUU A;  1V97 A;  3AN1 A;  3HSU A;  3TSH A;  2PLS A;  3FW9 A;  4PVJ A;  3W8Z A;  4UD8 A;  4MLA A;  5FXP A;  1E8G A;  5HHZ A;  1UXY A;  5G5G B;  5HQX A;  1FFU C;  3D2D A;  2BVG A;  3EJE B;  2IPI A;  3D2H A;  1N62 C;  3NVV B;  1N60 C;  2GQT A;  3NS1 B;  3FW8 A;  2RK5 A;  2I0K A;  2O3G A;  1JRO A;  3S1D A;  3DQ0 A;  1WVF A;  1W1L A;  4BBY A;  2E3T A;  3NVZ B;  5HMR A;  4BCA A;  3VTE A;  5FXD A;  2VFU A;  3JS8 A;  1W1J A;  1W1R A;  3BW7 A;  4PZF A;  4DNS A;  4BC9 A;  4PVH A;  3EUB 3;  3W8X A;  3EJB B;  1W1O A;  3HRD C;  3FWA A;  1E8H A;  1DIQ A;  3LLB A;  3FW7 A;  1FO4 A;  3D2J A;  4HG0 A;  1QLU A;  3TX1 A;  1JRP A;  3NVY B;  5ADZ A;  1WYG A;  1RM6 B;  5AWV A;  4ML8 A;  1SB3 B;  1T3Q C;  1QLT A;  5FXF A;  1N5W C;  2R8D A;  2NQW A;  1DII A;  5L6F A;  4OAL A;  2Q4W A;  2VAO A;  2Q85 A;  3AMZ A;  1N5X A;  3NRZ B;  2W3R A;  2BVH A;  2WDW A;  5K8E A;  2BVF A;  2VFR A;  3PM9 A;  1E0Y A;  1N61 C;  5AE3 A;  1FFV C;  3SR6 B;  2EXR A;  2W3S A;  1AHU A;  1MBB A;  1MBT A;  2VFT A;  4JB1 A;  5AE2 A;  4JAY A;  4XLO A;  4EC3 A;  3S1C A;  2P3H A;  2Y3S A;  5I1V A;  4ZOH B;  3EJD B;  4PVE A;  2W54 A;  4PWB A;  1VAO A;  3S1F A;  2Y3R A;  1HSK A;  2P13 A;  2OAI A;  2P4P A;  2VFV A;  3KJM A;  3C0P A;  2YVS A;  2PLI A;  3POP A;  1ZR6 A;  1DZN A;  2UUV A;  3S1E A;  4PVK A;  3PQB A;  3TSJ A;  1N63 C;  2AXR A;  1VDV A;  4O95 A;  3B9J B;  5D79 A;  2VFS A;  1AHZ A;  3DED A;  3GSY A;  2R2Z A;  4PYT A;  3RJA A;  3NVW B;  2Y08 A;  3LAE A;  3I99 A;  1I19 A;  3ETR B;  1WVE A;  5I1W A;  3W8W A;  2QKN A;  1W1Q A;  4BC7 A;  2QPM A;  5AE1 A;  2MBR A;  1W1M A;  1E8F A; 
#chains in the Genus database with same CATH homology
 1AHV A;  5FXE A;  4PWC A;  3AM9 A;  1W1K A;  1FIQ B;  1W1S A;  5G5H B;  1ZXI C;  1F0X A;  2W55 A;  5L6G A;  2GQU A;  2Y4G A;  3RJ8 A;  2UUU A;  1V97 A;  3AN1 A;  3HSU A;  3TSH A;  2PLS A;  3FW9 A;  4PVJ A;  3W8Z A;  4UD8 A;  4MLA A;  5FXP A;  1E8G A;  5HHZ A;  1UXY A;  5G5G B;  5HQX A;  1FFU C;  3D2D A;  2BVG A;  2IPI A;  3D2H A;  1N62 C;  3NVV B;  1N60 C;  2GQT A;  3NS1 B;  3FW8 A;  2RK5 A;  2I0K A;  2O3G A;  1JRO A;  3S1D A;  3DQ0 A;  1WVF A;  1W1L A;  4BBY A;  2E3T A;  3NVZ B;  5HMR A;  4BCA A;  3VTE A;  5FXD A;  2VFU A;  3JS8 A;  1W1J A;  1W1R A;  3BW7 A;  4PZF A;  4DNS A;  4BC9 A;  4PVH A;  3EUB 3;  3W8X A;  1W1O A;  3HRD C;  3FWA A;  1E8H A;  1DIQ A;  3LLB A;  3FW7 A;  1FO4 A;  3D2J A;  4HG0 A;  1QLU A;  3TX1 A;  1JRP A;  3NVY B;  5ADZ A;  1WYG A;  1RM6 B;  5AWV A;  4ML8 A;  1SB3 B;  1T3Q C;  1QLT A;  5FXF A;  1N5W C;  2R8D A;  2NQW A;  1DII A;  5L6F A;  4OAL A;  2Q4W A;  2VAO A;  2Q85 A;  3AMZ A;  1N5X A;  3NRZ B;  2W3R A;  2BVH A;  2WDW A;  5K8E A;  2BVF A;  2VFR A;  3PM9 A;  1E0Y A;  1N61 C;  5AE3 A;  1FFV C;  3SR6 B;  2EXR A;  2W3S A;  1AHU A;  1MBB A;  1MBT A;  2VFT A;  4JB1 A;  5AE2 A;  4JAY A;  4XLO A;  4EC3 A;  3S1C A;  2P3H A;  2Y3S A;  5I1V A;  4ZOH B;  4PVE A;  2W54 A;  4PWB A;  1VAO A;  3S1F A;  2Y3R A;  1HSK A;  2P13 A;  2OAI A;  2P4P A;  2VFV A;  3KJM A;  3C0P A;  2YVS A;  2PLI A;  3POP A;  1ZR6 A;  1DZN A;  2UUV A;  3S1E A;  4PVK A;  3PQB A;  3TSJ A;  1N63 C;  2AXR A;  1VDV A;  4O95 A;  3B9J B;  5D79 A;  2VFS A;  1AHZ A;  3DED A;  3GSY A;  2R2Z A;  4PYT A;  3RJA A;  2Y08 A;  3LAE A;  3NVW B;  3I99 A;  1I19 A;  3ETR B;  1WVE A;  5I1W A;  3W8W A;  2QKN A;  1W1Q A;  4BC7 A;  2QPM A;  5AE1 A;  2MBR A;  1W1M A;  1E8F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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