1W1MA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: glu502gly mutant
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGGYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
total genus 172
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1mA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1mA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1mA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1mA03
2W55A 5D79A 5ADZA 4OALA 5FXPA 2QPMA 3D2HA 2YVSA 1N5XA 1W1KA 3BW7A 3TSHA 4UD8A 1W1RA 4MLAA 1RM6B 3C0PA 3FW8A 3LAEA 5HMRA 3FW9A 1MBTA 3NVYB 1AHUA 1FIQB 2GQUA 3D2DA 3AN1A 1V97A 3D2JA 4O95A 2VFSA 2VFVA 3DEDA 3PM9A 3LLBA 3VTEA 2EXRA 2VFTA 3W8XA 2RK5A 1JRPA 3DQ0A 2BVGA 3NRZB 1F0XA 3W8ZA 2P4PA 1E8HA 1W1LA 1T3QC 1HSKA 3B9JB 4BC9A 3HRDC 5FXDA 2VAOA 5FXFA 2Q4WA 4PWBA 1W1MA 4BC7A 1N60C 1FO4A 4PVKA 1FFVC 4ML8A 1N63C 4JAYA 5AE3A 1VAOA 1AHZA 4PWCA 3S1DA 1AHVA 2E3TA 2R8DA 1WVEA 4PZFA 3TSJA 2Q85A 3W8WA 1DIQA 3SR6B 4PYTA 5G5HB 1W1QA 1ZR6A 1DIIA 2QKNA 3I99A 2VFRA 3AM9A 3ETRB 1ZXIC 5HHZA 1SB3B 1WYGA 1QLUA 2P13A 4ZOHB 2AXRA 3S1FA 1WVFA 2W3RA 3TX1A 2PLSA 5AE2A 1E8GA 3KJMA 1DZNA 1JROA 4PVJA 2R2ZA 1N61C 1W1OA 3NS1B 4BBYA 1W1JA 5HQXA 4XLOA 3S1CA 2BVHA 1I19A 1N5WC 5FXEA 2MBRA 1FFUC 4PVEA 2PLIA 2W54A 2P3HA 1UXYA 3NVZB 3S1EA 2BVFA 1E0YA 3GSYA 3FW7A 1MBBA 1QLTA 3JS8A 5G5GB 1VDVA 2GQTA 5AE1A 3AMZA 4EC3A 2VFUA 4BCAA 2W3SA 1E8FA 3EUB3 4DNSA 3NVVB 4PVHA 3FWAA 2OAIA 2I0KA 3NVWB 4HG0A 2O3GA 4JB1A 1N62C 1W1SA 2NQWA
chains in the Genus database with same CATH superfamily
2W55A 5D79A 5ADZA 4OALA 5FXPA 2QPMA 5L6FA 3D2HA 2YVSA 1N5XA 1W1KA 3BW7A 3TSHA 4UD8A 5I1VA 1W1RA 4MLAA 5L6GA 1RM6B 2IPIA 3C0PA 3FW8A 3LAEA 3EJDB 3FW9A 5HMRA 3EJEB 1MBTA 2UUVA 2WDWA 3NVYB 1AHUA 1FIQB 2GQUA 3D2DA 3AN1A 1V97A 3D2JA 4O95A 2VFSA 2VFVA 2Y3RA 3DEDA 3PM9A 3LLBA 3VTEA 2EXRA 2VFTA 5K8EA 3W8XA 3RJ8A 2RK5A 1JRPA 3DQ0A 5AWVA 2BVGA 3NRZB 5I1WA 1F0XA 3POPA 3W8ZA 2P4PA 2Y4GA 1E8HA 1W1LA 1T3QC 1HSKA 3B9JB 4BC9A 3HRDC 5FXDA 2VAOA 5FXFA 2Q4WA 4PWBA 1W1MA 4BC7A 1N60C 1FO4A 3RJAA 4PVKA 1FFVC 4ML8A 1N63C 4JAYA 5AE3A 1VAOA 1AHZA 4PWCA 3S1DA 1AHVA 2E3TA 2R8DA 1WVEA 3HSUA 4PZFA 3TSJA 2Q85A 3W8WA 1DIQA 3SR6B 4PYTA 5G5HB 1W1QA 1ZR6A 1DIIA 2QKNA 3I99A 2VFRA 3AM9A 3ETRB 1ZXIC 5HHZA 1SB3B 1WYGA 2Y08A 1QLUA 2P13A 4ZOHB 3PQBA 2AXRA 3S1FA 1WVFA 2W3RA 3TX1A 2PLSA 5AE2A 1E8GA 3KJMA 1DZNA 1JROA 4PVJA 2R2ZA 1N61C 1W1OA 3NS1B 4BBYA 1W1JA 5HQXA 4XLOA 3S1CA 2BVHA 2Y3SA 1I19A 1N5WC 2UUUA 5FXEA 2MBRA 1FFUC 4PVEA 2PLIA 2W54A 2P3HA 1UXYA 3NVZB 3S1EA 2BVFA 1E0YA 3EJBB 3GSYA 3FW7A 1MBBA 1QLTA 3JS8A 5G5GB 1VDVA 2GQTA 5AE1A 3AMZA 4EC3A 2VFUA 4BCAA 2W3SA 1E8FA 3EUB3 4DNSA 3NVVB 4PVHA 3FWAA 3NVWB 2I0KA 2OAIA 4HG0A 2O3GA 4JB1A 1N62C 1W1SA 2NQWA
chains in the Genus database with same CATH topology
2W55A 5D79A 5ADZA 4OALA 5FXPA 2QPMA 5L6FA 3D2HA 2YVSA 1N5XA 1W1KA 3BW7A 3TSHA 4UD8A 5I1VA 1W1RA 4MLAA 5L6GA 1RM6B 2IPIA 3C0PA 3FW8A 3LAEA 5HMRA 3FW9A 1MBTA 2UUVA 2WDWA 3NVYB 1AHUA 1FIQB 2GQUA 3D2DA 3AN1A 1V97A 3D2JA 4O95A 2VFSA 2VFVA 2Y3RA 3DEDA 3PM9A 3LLBA 3VTEA 2EXRA 2VFTA 5K8EA 3W8XA 3RJ8A 2RK5A 1JRPA 3DQ0A 5AWVA 2BVGA 3NRZB 5I1WA 1F0XA 3POPA 3W8ZA 2P4PA 2Y4GA 1E8HA 1W1LA 1T3QC 1HSKA 3B9JB 4BC9A 3HRDC 5FXDA 2VAOA 5FXFA 2Q4WA 4PWBA 1W1MA 4BC7A 1N60C 1FO4A 3RJAA 4PVKA 1FFVC 4ML8A 1N63C 4JAYA 5AE3A 1VAOA 1AHZA 4PWCA 3S1DA 1AHVA 2E3TA 2R8DA 1WVEA 3HSUA 4PZFA 3TSJA 2Q85A 3W8WA 1DIQA 3SR6B 4PYTA 5G5HB 1W1QA 1ZR6A 1DIIA 2QKNA 3I99A 2VFRA 3AM9A 3ETRB 1ZXIC 5HHZA 1SB3B 1WYGA 2Y08A 1QLUA 2P13A 4ZOHB 3PQBA 2AXRA 3S1FA 1WVFA 2W3RA 3TX1A 2PLSA 5AE2A 1E8GA 3KJMA 1DZNA 1JROA 4PVJA 2R2ZA 1N61C 1W1OA 3NS1B 4BBYA 1W1JA 5HQXA 4XLOA 3S1CA 2BVHA 2Y3SA 1I19A 1N5WC 2UUUA 5FXEA 2MBRA 1FFUC 4PVEA 2PLIA 2W54A 2P3HA 1UXYA 3NVZB 3S1EA 2BVFA 1E0YA 3GSYA 3FW7A 1MBBA 1QLTA 3JS8A 5G5GB 1VDVA 2GQTA 5AE1A 3AMZA 4EC3A 2VFUA 4BCAA 2W3SA 1E8FA 3EUB3 4DNSA 3NVVB 4PVHA 3FWAA 2OAIA 2I0KA 3NVWB 4HG0A 2O3GA 4JB1A 1N62C 1W1SA 2NQWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W55 A;  5D79 A;  5ADZ A;  4OAL A;  5FXP A;  2QPM A;  3D2H A;  2YVS A;  1N5X A;  1W1K A;  3BW7 A;  3TSH A;  4UD8 A;  1W1R A;  4MLA A;  1RM6 B;  3C0P A;  3FW8 A;  3LAE A;  5HMR A;  3FW9 A;  1MBT A;  3NVY B;  1AHU A;  1FIQ B;  2GQU A;  3D2D A;  3AN1 A;  1V97 A;  3D2J A;  4O95 A;  2VFS A;  2VFV A;  3DED A;  3PM9 A;  3LLB A;  3VTE A;  2EXR A;  2VFT A;  3W8X A;  2RK5 A;  1JRP A;  3DQ0 A;  2BVG A;  3NRZ B;  1F0X A;  3W8Z A;  2P4P A;  1E8H A;  1W1L A;  1T3Q C;  1HSK A;  3B9J B;  4BC9 A;  3HRD C;  5FXD A;  2VAO A;  5FXF A;  2Q4W A;  4PWB A;  1W1M A;  4BC7 A;  1N60 C;  1FO4 A;  4PVK A;  1FFV C;  4ML8 A;  1N63 C;  4JAY A;  5AE3 A;  1VAO A;  1AHZ A;  4PWC A;  3S1D A;  1AHV A;  2E3T A;  2R8D A;  1WVE A;  4PZF A;  3TSJ A;  2Q85 A;  3W8W A;  1DIQ A;  3SR6 B;  4PYT A;  5G5H B;  1W1Q A;  1ZR6 A;  1DII A;  2QKN A;  3I99 A;  2VFR A;  3AM9 A;  3ETR B;  1ZXI C;  5HHZ A;  1SB3 B;  1WYG A;  1QLU A;  2P13 A;  4ZOH B;  2AXR A;  3S1F A;  1WVF A;  2W3R A;  3TX1 A;  2PLS A;  5AE2 A;  1E8G A;  3KJM A;  1DZN A;  1JRO A;  4PVJ A;  2R2Z A;  1N61 C;  1W1O A;  3NS1 B;  4BBY A;  1W1J A;  5HQX A;  4XLO A;  3S1C A;  2BVH A;  1I19 A;  1N5W C;  5FXE A;  2MBR A;  1FFU C;  4PVE A;  2PLI A;  2W54 A;  2P3H A;  1UXY A;  3NVZ B;  3S1E A;  2BVF A;  1E0Y A;  3GSY A;  3FW7 A;  1MBB A;  1QLT A;  3JS8 A;  5G5G B;  1VDV A;  2GQT A;  5AE1 A;  3AMZ A;  4EC3 A;  2VFU A;  4BCA A;  2W3S A;  1E8F A;  3EUB 3;  4DNS A;  3NVV B;  4PVH A;  3FWA A;  2OAI A;  2I0K A;  3NVW B;  4HG0 A;  2O3G A;  4JB1 A;  1N62 C;  1W1S A;  2NQW A; 
#chains in the Genus database with same CATH topology
 2W55 A;  5D79 A;  5ADZ A;  4OAL A;  5FXP A;  2QPM A;  5L6F A;  3D2H A;  2YVS A;  1N5X A;  1W1K A;  3BW7 A;  3TSH A;  4UD8 A;  5I1V A;  1W1R A;  4MLA A;  5L6G A;  1RM6 B;  2IPI A;  3C0P A;  3FW8 A;  3LAE A;  3EJD B;  3FW9 A;  5HMR A;  3EJE B;  1MBT A;  2UUV A;  2WDW A;  3NVY B;  1AHU A;  1FIQ B;  2GQU A;  3D2D A;  3AN1 A;  1V97 A;  3D2J A;  4O95 A;  2VFS A;  2VFV A;  2Y3R A;  3DED A;  3PM9 A;  3LLB A;  3VTE A;  2EXR A;  2VFT A;  5K8E A;  3W8X A;  3RJ8 A;  2RK5 A;  1JRP A;  3DQ0 A;  5AWV A;  2BVG A;  3NRZ B;  5I1W A;  1F0X A;  3POP A;  3W8Z A;  2P4P A;  2Y4G A;  1E8H A;  1W1L A;  1T3Q C;  1HSK A;  3B9J B;  4BC9 A;  3HRD C;  5FXD A;  2VAO A;  5FXF A;  2Q4W A;  4PWB A;  1W1M A;  4BC7 A;  1N60 C;  1FO4 A;  3RJA A;  4PVK A;  1FFV C;  4ML8 A;  1N63 C;  4JAY A;  5AE3 A;  1VAO A;  1AHZ A;  4PWC A;  3S1D A;  1AHV A;  2E3T A;  2R8D A;  1WVE A;  3HSU A;  4PZF A;  3TSJ A;  2Q85 A;  3W8W A;  1DIQ A;  3SR6 B;  4PYT A;  5G5H B;  1W1Q A;  1ZR6 A;  1DII A;  2QKN A;  3I99 A;  2VFR A;  3AM9 A;  3ETR B;  1ZXI C;  5HHZ A;  1SB3 B;  1WYG A;  2Y08 A;  1QLU A;  2P13 A;  4ZOH B;  3PQB A;  2AXR A;  3S1F A;  1WVF A;  2W3R A;  3TX1 A;  2PLS A;  5AE2 A;  1E8G A;  3KJM A;  1DZN A;  1JRO A;  4PVJ A;  2R2Z A;  1N61 C;  1W1O A;  3NS1 B;  4BBY A;  1W1J A;  5HQX A;  4XLO A;  3S1C A;  2BVH A;  2Y3S A;  1I19 A;  1N5W C;  2UUU A;  5FXE A;  2MBR A;  1FFU C;  4PVE A;  2PLI A;  2W54 A;  2P3H A;  1UXY A;  3NVZ B;  3S1E A;  2BVF A;  1E0Y A;  3EJB B;  3GSY A;  3FW7 A;  1MBB A;  1QLT A;  3JS8 A;  5G5G B;  1VDV A;  2GQT A;  5AE1 A;  3AMZ A;  4EC3 A;  2VFU A;  4BCA A;  2W3S A;  1E8F A;  3EUB 3;  4DNS A;  3NVV B;  4PVH A;  3FWA A;  3NVW B;  2I0K A;  2OAI A;  4HG0 A;  2O3G A;  4JB1 A;  1N62 C;  1W1S A;  2NQW A; 
#chains in the Genus database with same CATH homology
 2W55 A;  5D79 A;  5ADZ A;  4OAL A;  5FXP A;  2QPM A;  5L6F A;  3D2H A;  2YVS A;  1N5X A;  1W1K A;  3BW7 A;  3TSH A;  4UD8 A;  5I1V A;  1W1R A;  4MLA A;  5L6G A;  1RM6 B;  2IPI A;  3C0P A;  3FW8 A;  3LAE A;  5HMR A;  3FW9 A;  1MBT A;  2UUV A;  2WDW A;  3NVY B;  1AHU A;  1FIQ B;  2GQU A;  3D2D A;  3AN1 A;  1V97 A;  3D2J A;  4O95 A;  2VFS A;  2VFV A;  2Y3R A;  3DED A;  3PM9 A;  3LLB A;  3VTE A;  2EXR A;  2VFT A;  5K8E A;  3W8X A;  3RJ8 A;  2RK5 A;  1JRP A;  3DQ0 A;  5AWV A;  2BVG A;  3NRZ B;  5I1W A;  1F0X A;  3POP A;  3W8Z A;  2P4P A;  2Y4G A;  1E8H A;  1W1L A;  1T3Q C;  1HSK A;  3B9J B;  4BC9 A;  3HRD C;  5FXD A;  2VAO A;  5FXF A;  2Q4W A;  4PWB A;  1W1M A;  4BC7 A;  1N60 C;  1FO4 A;  3RJA A;  4PVK A;  1FFV C;  4ML8 A;  1N63 C;  4JAY A;  5AE3 A;  1VAO A;  1AHZ A;  4PWC A;  3S1D A;  1AHV A;  2E3T A;  2R8D A;  1WVE A;  3HSU A;  4PZF A;  3TSJ A;  2Q85 A;  3W8W A;  1DIQ A;  3SR6 B;  4PYT A;  5G5H B;  1W1Q A;  1ZR6 A;  1DII A;  2QKN A;  3I99 A;  2VFR A;  3AM9 A;  3ETR B;  1ZXI C;  5HHZ A;  1SB3 B;  1WYG A;  2Y08 A;  1QLU A;  2P13 A;  4ZOH B;  3PQB A;  2AXR A;  3S1F A;  1WVF A;  2W3R A;  3TX1 A;  2PLS A;  5AE2 A;  1E8G A;  3KJM A;  1DZN A;  1JRO A;  4PVJ A;  2R2Z A;  1N61 C;  1W1O A;  3NS1 B;  4BBY A;  1W1J A;  5HQX A;  4XLO A;  3S1C A;  2BVH A;  2Y3S A;  1I19 A;  1N5W C;  2UUU A;  5FXE A;  2MBR A;  1FFU C;  4PVE A;  2PLI A;  2W54 A;  2P3H A;  1UXY A;  3NVZ B;  3S1E A;  2BVF A;  1E0Y A;  3GSY A;  3FW7 A;  1MBB A;  1QLT A;  3JS8 A;  5G5G B;  1VDV A;  2GQT A;  5AE1 A;  3AMZ A;  4EC3 A;  2VFU A;  4BCA A;  2W3S A;  1E8F A;  3EUB 3;  4DNS A;  3NVV B;  4PVH A;  3FWA A;  2OAI A;  2I0K A;  3NVW B;  4HG0 A;  2O3G A;  4JB1 A;  1N62 C;  1W1S A;  2NQW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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