2GQUA

Crystal structure of udp-n-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
266
structure length
266
Chain Sequence
b'FMRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQARAKDVLELVRRVQEELPLELEWEVWP'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-N-Acetylenolpyruvylglucosamine Reductase
publication title Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
pubmed doi rcsb
source organism Thermus caldophilus
molecule tags Oxidoreductase
total genus 79
structure length 266
sequence length 266
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2006-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2gquA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2gquA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2gquA03
3W8XA 1SB3B 2OAIA 2VFRA 1E8HA 5G5HB 1DZNA 2NQWA 3HRDC 1MBTA 5FXDA 5HMRA 3D2JA 4JAYA 1QLUA 1WYGA 2R2ZA 3FW7A 2I0KA 5HHZA 2RK5A 5ADZA 1I19A 1E8FA 1W1JA 4BC7A 5FXPA 2Q4WA 4PVHA 4DNSA 3EUB3 3FWAA 3PM9A 3S1FA 5AE2A 1FFUC 1FO4A 4PZFA 1AHVA 2VFUA 1W1SA 1JROA 1ZXIC 3AMZA 2Q85A 1W1LA 2W55A 2VAOA 3S1CA 3TX1A 4ML8A 1W1KA 1JRPA 5FXFA 3D2DA 2PLSA 3AM9A 4PYTA 3DQ0A 2GQTA 3LLBA 2QPMA 4HG0A 3LAEA 1WVEA 1N63C 4PWCA 2BVFA 2R8DA 5FXEA 4MLAA 1E0YA 3S1EA 4UD8A 1DIQA 4EC3A 1VAOA 2P4PA 1UXYA 1F0XA 3D2HA 2P3HA 4JB1A 2W54A 4ZOHB 2W3RA 2EXRA 4PVJA 3ETRB 4O95A 2O3GA 3S1DA 1AHZA 3NRZB 1DIIA 3TSJA 3GSYA 1W1OA 1VDVA 5AE3A 1HSKA 5AE1A 4XLOA 1WVFA 2VFSA 2VFTA 2BVHA 1MBBA 3SR6B 4OALA 3NS1B 1N5XA 3NVYB 4PVEA 3W8WA 5HQXA 5D79A 1N60C 3AN1A 1AHUA 3VTEA 1N62C 1V97A 1ZR6A 4BC9A 2GQUA 3NVWB 2QKNA 1W1MA 3TSHA 4PVKA 2MBRA 4BCAA 4PWBA 1N61C 3B9JB 5G5GB 1FFVC 1W1RA 1QLTA 1W1QA 1T3QC 1FIQB 3DEDA 3NVVB 3W8ZA 2VFVA 1N5WC 3FW8A 3JS8A 3C0PA 2PLIA 3FW9A 2YVSA 3KJMA 2AXRA 3BW7A 2BVGA 3I99A 2P13A 2W3SA 1RM6B 2E3TA 3NVZB 4BBYA 1E8GA
chains in the Genus database with same CATH superfamily
3W8XA 1SB3B 2OAIA 2VFRA 1E8HA 2Y08A 3EJEB 5G5HB 1DZNA 2NQWA 3HRDC 1MBTA 5FXDA 5HMRA 3D2JA 4JAYA 1QLUA 5L6GA 1WYGA 2R2ZA 5L6FA 3HSUA 3FW7A 2I0KA 5HHZA 2RK5A 5ADZA 1I19A 1E8FA 1W1JA 4BC7A 5FXPA 2UUVA 2Q4WA 4PVHA 4DNSA 3EUB3 3FWAA 3PM9A 3S1FA 5AE2A 1FFUC 1FO4A 4PZFA 1AHVA 2VFUA 1W1SA 1JROA 1ZXIC 3AMZA 2Q85A 1W1LA 2W55A 2VAOA 3S1CA 3TX1A 4ML8A 1W1KA 1JRPA 5FXFA 2Y4GA 3D2DA 2PLSA 3AM9A 4PYTA 3DQ0A 2GQTA 3EJDB 3LLBA 2QPMA 4HG0A 3LAEA 1WVEA 1N63C 4PWCA 2BVFA 2R8DA 5AWVA 5FXEA 4MLAA 1E0YA 3S1EA 4UD8A 1DIQA 4EC3A 1VAOA 2P4PA 1UXYA 1F0XA 5I1WA 3D2HA 3EJBB 2P3HA 4JB1A 2W54A 4ZOHB 2W3RA 2EXRA 2WDWA 4PVJA 3ETRB 4O95A 2O3GA 3S1DA 1AHZA 3NRZB 1DIIA 2IPIA 3TSJA 3RJAA 3GSYA 1W1OA 1VDVA 5AE3A 3RJ8A 1HSKA 5AE1A 4XLOA 1WVFA 2VFSA 2VFTA 5I1VA 2BVHA 1MBBA 3SR6B 4OALA 3NS1B 1N5XA 3NVYB 2UUUA 4PVEA 3W8WA 5HQXA 5D79A 1N60C 3AN1A 1AHUA 3VTEA 1N62C 1V97A 1ZR6A 4BC9A 2GQUA 3PQBA 3NVWB 2QKNA 1W1MA 3TSHA 4PVKA 2MBRA 4BCAA 4PWBA 5K8EA 1N61C 3B9JB 5G5GB 1FFVC 1W1RA 1QLTA 1W1QA 1T3QC 1FIQB 3DEDA 3NVVB 3W8ZA 2VFVA 3POPA 1N5WC 3FW8A 3JS8A 3C0PA 2PLIA 3FW9A 2Y3SA 2YVSA 3KJMA 2AXRA 3BW7A 2BVGA 3I99A 2P13A 2Y3RA 2W3SA 1RM6B 2E3TA 3NVZB 4BBYA 1E8GA
chains in the Genus database with same CATH topology
3W8XA 1SB3B 2OAIA 2VFRA 1E8HA 2Y08A 5G5HB 1DZNA 2NQWA 3HRDC 1MBTA 5FXDA 5HMRA 3D2JA 4JAYA 1QLUA 5L6GA 1WYGA 2R2ZA 5L6FA 3HSUA 3FW7A 2I0KA 5HHZA 2RK5A 5ADZA 1I19A 1E8FA 1W1JA 4BC7A 5FXPA 2UUVA 2Q4WA 4PVHA 4DNSA 3EUB3 3FWAA 3PM9A 3S1FA 5AE2A 1FFUC 1FO4A 4PZFA 1AHVA 2VFUA 1W1SA 1JROA 1ZXIC 3AMZA 2Q85A 1W1LA 2W55A 2VAOA 3S1CA 3TX1A 4ML8A 1W1KA 1JRPA 5FXFA 2Y4GA 3D2DA 2PLSA 3AM9A 4PYTA 3DQ0A 2GQTA 3LLBA 2QPMA 4HG0A 3LAEA 1WVEA 1N63C 4PWCA 2BVFA 2R8DA 5AWVA 5FXEA 4MLAA 1E0YA 3S1EA 4UD8A 1DIQA 4EC3A 1VAOA 2P4PA 1UXYA 1F0XA 5I1WA 3D2HA 2P3HA 4JB1A 2W54A 4ZOHB 2W3RA 2EXRA 2WDWA 4PVJA 3ETRB 4O95A 2O3GA 3S1DA 1AHZA 3NRZB 1DIIA 2IPIA 3TSJA 3RJAA 3GSYA 1W1OA 1VDVA 5AE3A 3RJ8A 1HSKA 5AE1A 4XLOA 1WVFA 2VFSA 2VFTA 5I1VA 2BVHA 1MBBA 3SR6B 4OALA 3NS1B 1N5XA 3NVYB 2UUUA 4PVEA 3W8WA 5HQXA 5D79A 1N60C 3AN1A 1AHUA 3VTEA 1N62C 1V97A 1ZR6A 4BC9A 2GQUA 3PQBA 3NVWB 2QKNA 1W1MA 3TSHA 4PVKA 2MBRA 4BCAA 4PWBA 5K8EA 1N61C 3B9JB 5G5GB 1FFVC 1W1RA 1QLTA 1W1QA 1T3QC 1FIQB 3DEDA 3NVVB 3W8ZA 2VFVA 3POPA 1N5WC 3FW8A 3JS8A 3C0PA 2PLIA 3FW9A 2Y3SA 2YVSA 3KJMA 2AXRA 3BW7A 2BVGA 3I99A 2P13A 2Y3RA 2W3SA 1RM6B 2E3TA 3NVZB 4BBYA 1E8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8X A;  1SB3 B;  2OAI A;  2VFR A;  1E8H A;  5G5H B;  1DZN A;  2NQW A;  3HRD C;  1MBT A;  5FXD A;  5HMR A;  3D2J A;  4JAY A;  1QLU A;  1WYG A;  2R2Z A;  3FW7 A;  2I0K A;  5HHZ A;  2RK5 A;  5ADZ A;  1I19 A;  1E8F A;  1W1J A;  4BC7 A;  5FXP A;  2Q4W A;  4PVH A;  4DNS A;  3EUB 3;  3FWA A;  3PM9 A;  3S1F A;  5AE2 A;  1FFU C;  1FO4 A;  4PZF A;  1AHV A;  2VFU A;  1W1S A;  1JRO A;  1ZXI C;  3AMZ A;  2Q85 A;  1W1L A;  2W55 A;  2VAO A;  3S1C A;  3TX1 A;  4ML8 A;  1W1K A;  1JRP A;  5FXF A;  3D2D A;  2PLS A;  3AM9 A;  4PYT A;  3DQ0 A;  2GQT A;  3LLB A;  2QPM A;  4HG0 A;  3LAE A;  1WVE A;  1N63 C;  4PWC A;  2BVF A;  2R8D A;  5FXE A;  4MLA A;  1E0Y A;  3S1E A;  4UD8 A;  1DIQ A;  4EC3 A;  1VAO A;  2P4P A;  1UXY A;  1F0X A;  3D2H A;  2P3H A;  4JB1 A;  2W54 A;  4ZOH B;  2W3R A;  2EXR A;  4PVJ A;  3ETR B;  4O95 A;  2O3G A;  3S1D A;  1AHZ A;  3NRZ B;  1DII A;  3TSJ A;  3GSY A;  1W1O A;  1VDV A;  5AE3 A;  1HSK A;  5AE1 A;  4XLO A;  1WVF A;  2VFS A;  2VFT A;  2BVH A;  1MBB A;  3SR6 B;  4OAL A;  3NS1 B;  1N5X A;  3NVY B;  4PVE A;  3W8W A;  5HQX A;  5D79 A;  1N60 C;  3AN1 A;  1AHU A;  3VTE A;  1N62 C;  1V97 A;  1ZR6 A;  4BC9 A;  2GQU A;  3NVW B;  2QKN A;  1W1M A;  3TSH A;  4PVK A;  2MBR A;  4BCA A;  4PWB A;  1N61 C;  3B9J B;  5G5G B;  1FFV C;  1W1R A;  1QLT A;  1W1Q A;  1T3Q C;  1FIQ B;  3DED A;  3NVV B;  3W8Z A;  2VFV A;  1N5W C;  3FW8 A;  3JS8 A;  3C0P A;  2PLI A;  3FW9 A;  2YVS A;  3KJM A;  2AXR A;  3BW7 A;  2BVG A;  3I99 A;  2P13 A;  2W3S A;  1RM6 B;  2E3T A;  3NVZ B;  4BBY A;  1E8G A; 
#chains in the Genus database with same CATH topology
 3W8X A;  1SB3 B;  2OAI A;  2VFR A;  1E8H A;  2Y08 A;  3EJE B;  5G5H B;  1DZN A;  2NQW A;  3HRD C;  1MBT A;  5FXD A;  5HMR A;  3D2J A;  4JAY A;  1QLU A;  5L6G A;  1WYG A;  2R2Z A;  5L6F A;  3HSU A;  3FW7 A;  2I0K A;  5HHZ A;  2RK5 A;  5ADZ A;  1I19 A;  1E8F A;  1W1J A;  4BC7 A;  5FXP A;  2UUV A;  2Q4W A;  4PVH A;  4DNS A;  3EUB 3;  3FWA A;  3PM9 A;  3S1F A;  5AE2 A;  1FFU C;  1FO4 A;  4PZF A;  1AHV A;  2VFU A;  1W1S A;  1JRO A;  1ZXI C;  3AMZ A;  2Q85 A;  1W1L A;  2W55 A;  2VAO A;  3S1C A;  3TX1 A;  4ML8 A;  1W1K A;  1JRP A;  5FXF A;  2Y4G A;  3D2D A;  2PLS A;  3AM9 A;  4PYT A;  3DQ0 A;  2GQT A;  3EJD B;  3LLB A;  2QPM A;  4HG0 A;  3LAE A;  1WVE A;  1N63 C;  4PWC A;  2BVF A;  2R8D A;  5AWV A;  5FXE A;  4MLA A;  1E0Y A;  3S1E A;  4UD8 A;  1DIQ A;  4EC3 A;  1VAO A;  2P4P A;  1UXY A;  1F0X A;  5I1W A;  3D2H A;  3EJB B;  2P3H A;  4JB1 A;  2W54 A;  4ZOH B;  2W3R A;  2EXR A;  2WDW A;  4PVJ A;  3ETR B;  4O95 A;  2O3G A;  3S1D A;  1AHZ A;  3NRZ B;  1DII A;  2IPI A;  3TSJ A;  3RJA A;  3GSY A;  1W1O A;  1VDV A;  5AE3 A;  3RJ8 A;  1HSK A;  5AE1 A;  4XLO A;  1WVF A;  2VFS A;  2VFT A;  5I1V A;  2BVH A;  1MBB A;  3SR6 B;  4OAL A;  3NS1 B;  1N5X A;  3NVY B;  2UUU A;  4PVE A;  3W8W A;  5HQX A;  5D79 A;  1N60 C;  3AN1 A;  1AHU A;  3VTE A;  1N62 C;  1V97 A;  1ZR6 A;  4BC9 A;  2GQU A;  3PQB A;  3NVW B;  2QKN A;  1W1M A;  3TSH A;  4PVK A;  2MBR A;  4BCA A;  4PWB A;  5K8E A;  1N61 C;  3B9J B;  5G5G B;  1FFV C;  1W1R A;  1QLT A;  1W1Q A;  1T3Q C;  1FIQ B;  3DED A;  3NVV B;  3W8Z A;  2VFV A;  3POP A;  1N5W C;  3FW8 A;  3JS8 A;  3C0P A;  2PLI A;  3FW9 A;  2Y3S A;  2YVS A;  3KJM A;  2AXR A;  3BW7 A;  2BVG A;  3I99 A;  2P13 A;  2Y3R A;  2W3S A;  1RM6 B;  2E3T A;  3NVZ B;  4BBY A;  1E8G A; 
#chains in the Genus database with same CATH homology
 3W8X A;  1SB3 B;  2OAI A;  2VFR A;  1E8H A;  2Y08 A;  5G5H B;  1DZN A;  2NQW A;  3HRD C;  1MBT A;  5FXD A;  5HMR A;  3D2J A;  4JAY A;  1QLU A;  5L6G A;  1WYG A;  2R2Z A;  5L6F A;  3HSU A;  3FW7 A;  2I0K A;  5HHZ A;  2RK5 A;  5ADZ A;  1I19 A;  1E8F A;  1W1J A;  4BC7 A;  5FXP A;  2UUV A;  2Q4W A;  4PVH A;  4DNS A;  3EUB 3;  3FWA A;  3PM9 A;  3S1F A;  5AE2 A;  1FFU C;  1FO4 A;  4PZF A;  1AHV A;  2VFU A;  1W1S A;  1JRO A;  1ZXI C;  3AMZ A;  2Q85 A;  1W1L A;  2W55 A;  2VAO A;  3S1C A;  3TX1 A;  4ML8 A;  1W1K A;  1JRP A;  5FXF A;  2Y4G A;  3D2D A;  2PLS A;  3AM9 A;  4PYT A;  3DQ0 A;  2GQT A;  3LLB A;  2QPM A;  4HG0 A;  3LAE A;  1WVE A;  1N63 C;  4PWC A;  2BVF A;  2R8D A;  5AWV A;  5FXE A;  4MLA A;  1E0Y A;  3S1E A;  4UD8 A;  1DIQ A;  4EC3 A;  1VAO A;  2P4P A;  1UXY A;  1F0X A;  5I1W A;  3D2H A;  2P3H A;  4JB1 A;  2W54 A;  4ZOH B;  2W3R A;  2EXR A;  2WDW A;  4PVJ A;  3ETR B;  4O95 A;  2O3G A;  3S1D A;  1AHZ A;  3NRZ B;  1DII A;  2IPI A;  3TSJ A;  3RJA A;  3GSY A;  1W1O A;  1VDV A;  5AE3 A;  3RJ8 A;  1HSK A;  5AE1 A;  4XLO A;  1WVF A;  2VFS A;  2VFT A;  5I1V A;  2BVH A;  1MBB A;  3SR6 B;  4OAL A;  3NS1 B;  1N5X A;  3NVY B;  2UUU A;  4PVE A;  3W8W A;  5HQX A;  5D79 A;  1N60 C;  3AN1 A;  1AHU A;  3VTE A;  1N62 C;  1V97 A;  1ZR6 A;  4BC9 A;  2GQU A;  3PQB A;  3NVW B;  2QKN A;  1W1M A;  3TSH A;  4PVK A;  2MBR A;  4BCA A;  4PWB A;  5K8E A;  1N61 C;  3B9J B;  5G5G B;  1FFV C;  1W1R A;  1QLT A;  1W1Q A;  1T3Q C;  1FIQ B;  3DED A;  3NVV B;  3W8Z A;  2VFV A;  3POP A;  1N5W C;  3FW8 A;  3JS8 A;  3C0P A;  2PLI A;  3FW9 A;  2Y3S A;  2YVS A;  3KJM A;  2AXR A;  3BW7 A;  2BVG A;  3I99 A;  2P13 A;  2Y3R A;  2W3S A;  1RM6 B;  2E3T A;  3NVZ B;  4BBY A;  1E8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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