2GQUA

Crystal structure of udp-n-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
266
structure length
266
Chain Sequence
FMRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQARAKDVLELVRRVQEELPLELEWEVWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords UDP-N-Acetylenolpyruvylglucosamine Reductase
publication title Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
pubmed doi rcsb
source organism Thermus caldophilus
total genus 79
structure length 266
sequence length 266
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2006-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2gquA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2gquA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2gquA03
2I0KA 1N63C 2VFRA 1UXYA 2GQUA 4ZOHB 1HSKA 3FW8A 3TSHA 3S1EA 2R8DA 3NVWB 2BVHA 1QLUA 2VFSA 3AMZA 3KJMA 1WVFA 4DNSA 2R2ZA 2YVSA 3TSJA 1DZNA 1F0XA 1N5XA 2MBRA 1W1MA 1SB3B 1N62C 4JB1A 3LLBA 4PWCA 2W3SA 1W1QA 1W1RA 2AXRA 2P13A 4BC7A 2VFTA 1W1LA 1JROA 2EXRA 4PZFA 1N5WC 1VAOA 1ZR6A 4XLOA 3NVVB 3NS1B 5FXEA 1N60C 4HG0A 4PYTA 3TX1A 3EUB3 3NVZB 5D79A 2Q4WA 1I19A 3BW7A 1T3QC 1JRPA 5FXPA 4PWBA 3S1FA 1E8GA 5HMRA 2P3HA 2OAIA 2PLSA 3D2JA 1MBBA 4BCAA 4PVKA 1DIQA 3FWAA 2RK5A 3JS8A 1RM6B 5HHZA 5G5HB 2Q85A 3VTEA 1WYGA 3NRZB 1W1JA 3PM9A 1FIQB 4PVJA 2W54A 3I99A 1V97A 2VAOA 1W1OA 2VFUA 3S1DA 3LAEA 2BVFA 1N61C 5AE1A 4BBYA 3GSYA 1E8HA 5AE3A 1E8FA 1VDVA 2VFVA 1AHUA 1DIIA 3SR6B 4BC9A 1FFUC 4O95A 2QKNA 4MLAA 3W8XA 2PLIA 1FFVC 2E3TA 3B9JB 3FW7A 3DEDA 5G5GB 4PVHA 4JAYA 2QPMA 3W8ZA 2NQWA 4UD8A 1WVEA 4OALA 1W1KA 5AE2A 3AM9A 1QLTA 1FO4A 5HQXA 3DQ0A 1ZXIC 4EC3A 3C0PA 5FXDA 3D2HA 3S1CA 3ETRB 5FXFA 3FW9A 2P4PA 3W8WA 2W3RA 1MBTA 3HRDC 1W1SA 2GQTA 1AHZA 1AHVA 4PVEA 3D2DA 3NVYB 1E0YA 2O3GA 4ML8A 2W55A 2BVGA 5ADZA 3AN1A
chains in the Genus database with same CATH superfamily
2I0KA 5I1WA 1N63C 2VFRA 1UXYA 2GQUA 3NVWB 1HSKA 3FW8A 4ZOHB 3S1EA 3TSHA 2R8DA 2BVHA 1QLUA 2VFSA 3AMZA 3KJMA 1WVFA 4DNSA 2R2ZA 3RJ8A 2YVSA 3TSJA 1DZNA 1F0XA 1N5XA 2MBRA 1W1MA 1SB3B 2Y3RA 1N62C 4JB1A 2Y08A 3LLBA 3EJEB 2W3SA 4PWCA 2UUUA 3EJDB 1W1QA 1W1RA 2AXRA 2P13A 4BC7A 2VFTA 1W1LA 1JROA 2UUVA 2EXRA 4PZFA 1N5WC 1VAOA 1ZR6A 3NVVB 4XLOA 5AWVA 3NS1B 5FXEA 1N60C 2Y4GA 4HG0A 4PYTA 3TX1A 3EUB3 3NVZB 5D79A 2Q4WA 1I19A 3BW7A 1T3QC 1JRPA 5FXPA 4PWBA 3S1FA 2IPIA 1E8GA 5HMRA 2P3HA 2OAIA 2PLSA 3D2JA 1MBBA 4BCAA 2Y3SA 4PVKA 1DIQA 5L6FA 3FWAA 2RK5A 3JS8A 1RM6B 5HHZA 5G5HB 5I1VA 2Q85A 3RJAA 3VTEA 1WYGA 3NRZB 1W1JA 3PM9A 1FIQB 4PVJA 2W54A 3EJBB 3I99A 3POPA 1V97A 2VAOA 1W1OA 2VFUA 3S1DA 3LAEA 2BVFA 1N61C 5AE1A 5K8EA 4BBYA 3GSYA 1E8HA 5AE3A 1E8FA 3PQBA 1VDVA 5L6GA 2VFVA 1AHUA 1DIIA 3SR6B 4BC9A 1FFUC 4O95A 2QKNA 4MLAA 3W8XA 2PLIA 1FFVC 2E3TA 3B9JB 3FW7A 3DEDA 5G5GB 4PVHA 4JAYA 2QPMA 3W8ZA 2NQWA 4UD8A 1WVEA 4OALA 1W1KA 5AE2A 3AM9A 1QLTA 1FO4A 5HQXA 3DQ0A 1ZXIC 4EC3A 3C0PA 5FXDA 3D2HA 3S1CA 3ETRB 5FXFA 3FW9A 2WDWA 2P4PA 3W8WA 2W3RA 1MBTA 3HRDC 1W1SA 2GQTA 3HSUA 1AHZA 1AHVA 4PVEA 3D2DA 3NVYB 1E0YA 2O3GA 4ML8A 2W55A 2BVGA 5ADZA 3AN1A
chains in the Genus database with same CATH topology
2I0KA 5I1WA 1N63C 2VFRA 1UXYA 2GQUA 4ZOHB 1HSKA 3FW8A 3TSHA 3S1EA 2R8DA 3NVWB 2BVHA 1QLUA 2VFSA 3AMZA 3KJMA 1WVFA 4DNSA 2R2ZA 3RJ8A 2YVSA 3TSJA 1DZNA 1F0XA 1N5XA 2MBRA 1W1MA 1SB3B 2Y3RA 1N62C 4JB1A 2Y08A 3LLBA 4PWCA 2W3SA 2UUUA 1W1QA 1W1RA 2AXRA 2P13A 4BC7A 2VFTA 1W1LA 1JROA 2UUVA 2EXRA 4PZFA 1N5WC 1VAOA 1ZR6A 4XLOA 3NVVB 5AWVA 3NS1B 5FXEA 1N60C 2Y4GA 4HG0A 4PYTA 3TX1A 3EUB3 3NVZB 5D79A 2Q4WA 1I19A 3BW7A 1T3QC 1JRPA 5FXPA 4PWBA 3S1FA 2IPIA 1E8GA 5HMRA 2P3HA 2OAIA 2PLSA 3D2JA 1MBBA 4BCAA 2Y3SA 4PVKA 1DIQA 5L6FA 3FWAA 2RK5A 3JS8A 1RM6B 5HHZA 5G5HB 5I1VA 2Q85A 3RJAA 3VTEA 1WYGA 3NRZB 1W1JA 3PM9A 1FIQB 4PVJA 2W54A 3I99A 3POPA 1V97A 2VAOA 1W1OA 2VFUA 3S1DA 3LAEA 2BVFA 1N61C 5AE1A 5K8EA 4BBYA 3GSYA 1E8HA 5AE3A 1E8FA 3PQBA 1VDVA 5L6GA 2VFVA 1AHUA 1DIIA 3SR6B 4BC9A 1FFUC 4O95A 2QKNA 4MLAA 3W8XA 2PLIA 1FFVC 2E3TA 3B9JB 3FW7A 3DEDA 5G5GB 4PVHA 4JAYA 2QPMA 3W8ZA 2NQWA 4UD8A 1WVEA 4OALA 1W1KA 5AE2A 3AM9A 1QLTA 1FO4A 5HQXA 3DQ0A 1ZXIC 4EC3A 3C0PA 5FXDA 3D2HA 3S1CA 3ETRB 5FXFA 3FW9A 2WDWA 2P4PA 3W8WA 2W3RA 1MBTA 3HRDC 1W1SA 2GQTA 3HSUA 1AHZA 1AHVA 4PVEA 3D2DA 3NVYB 1E0YA 2O3GA 4ML8A 2W55A 2BVGA 5ADZA 3AN1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I0K A;  1N63 C;  2VFR A;  1UXY A;  2GQU A;  4ZOH B;  1HSK A;  3FW8 A;  3TSH A;  3S1E A;  2R8D A;  3NVW B;  2BVH A;  1QLU A;  2VFS A;  3AMZ A;  3KJM A;  1WVF A;  4DNS A;  2R2Z A;  2YVS A;  3TSJ A;  1DZN A;  1F0X A;  1N5X A;  2MBR A;  1W1M A;  1SB3 B;  1N62 C;  4JB1 A;  3LLB A;  4PWC A;  2W3S A;  1W1Q A;  1W1R A;  2AXR A;  2P13 A;  4BC7 A;  2VFT A;  1W1L A;  1JRO A;  2EXR A;  4PZF A;  1N5W C;  1VAO A;  1ZR6 A;  4XLO A;  3NVV B;  3NS1 B;  5FXE A;  1N60 C;  4HG0 A;  4PYT A;  3TX1 A;  3EUB 3;  3NVZ B;  5D79 A;  2Q4W A;  1I19 A;  3BW7 A;  1T3Q C;  1JRP A;  5FXP A;  4PWB A;  3S1F A;  1E8G A;  5HMR A;  2P3H A;  2OAI A;  2PLS A;  3D2J A;  1MBB A;  4BCA A;  4PVK A;  1DIQ A;  3FWA A;  2RK5 A;  3JS8 A;  1RM6 B;  5HHZ A;  5G5H B;  2Q85 A;  3VTE A;  1WYG A;  3NRZ B;  1W1J A;  3PM9 A;  1FIQ B;  4PVJ A;  2W54 A;  3I99 A;  1V97 A;  2VAO A;  1W1O A;  2VFU A;  3S1D A;  3LAE A;  2BVF A;  1N61 C;  5AE1 A;  4BBY A;  3GSY A;  1E8H A;  5AE3 A;  1E8F A;  1VDV A;  2VFV A;  1AHU A;  1DII A;  3SR6 B;  4BC9 A;  1FFU C;  4O95 A;  2QKN A;  4MLA A;  3W8X A;  2PLI A;  1FFV C;  2E3T A;  3B9J B;  3FW7 A;  3DED A;  5G5G B;  4PVH A;  4JAY A;  2QPM A;  3W8Z A;  2NQW A;  4UD8 A;  1WVE A;  4OAL A;  1W1K A;  5AE2 A;  3AM9 A;  1QLT A;  1FO4 A;  5HQX A;  3DQ0 A;  1ZXI C;  4EC3 A;  3C0P A;  5FXD A;  3D2H A;  3S1C A;  3ETR B;  5FXF A;  3FW9 A;  2P4P A;  3W8W A;  2W3R A;  1MBT A;  3HRD C;  1W1S A;  2GQT A;  1AHZ A;  1AHV A;  4PVE A;  3D2D A;  3NVY B;  1E0Y A;  2O3G A;  4ML8 A;  2W55 A;  2BVG A;  5ADZ A;  3AN1 A; 
#chains in the Genus database with same CATH topology
 2I0K A;  5I1W A;  1N63 C;  2VFR A;  1UXY A;  2GQU A;  3NVW B;  1HSK A;  3FW8 A;  4ZOH B;  3S1E A;  3TSH A;  2R8D A;  2BVH A;  1QLU A;  2VFS A;  3AMZ A;  3KJM A;  1WVF A;  4DNS A;  2R2Z A;  3RJ8 A;  2YVS A;  3TSJ A;  1DZN A;  1F0X A;  1N5X A;  2MBR A;  1W1M A;  1SB3 B;  2Y3R A;  1N62 C;  4JB1 A;  2Y08 A;  3LLB A;  3EJE B;  2W3S A;  4PWC A;  2UUU A;  3EJD B;  1W1Q A;  1W1R A;  2AXR A;  2P13 A;  4BC7 A;  2VFT A;  1W1L A;  1JRO A;  2UUV A;  2EXR A;  4PZF A;  1N5W C;  1VAO A;  1ZR6 A;  3NVV B;  4XLO A;  5AWV A;  3NS1 B;  5FXE A;  1N60 C;  2Y4G A;  4HG0 A;  4PYT A;  3TX1 A;  3EUB 3;  3NVZ B;  5D79 A;  2Q4W A;  1I19 A;  3BW7 A;  1T3Q C;  1JRP A;  5FXP A;  4PWB A;  3S1F A;  2IPI A;  1E8G A;  5HMR A;  2P3H A;  2OAI A;  2PLS A;  3D2J A;  1MBB A;  4BCA A;  2Y3S A;  4PVK A;  1DIQ A;  5L6F A;  3FWA A;  2RK5 A;  3JS8 A;  1RM6 B;  5HHZ A;  5G5H B;  5I1V A;  2Q85 A;  3RJA A;  3VTE A;  1WYG A;  3NRZ B;  1W1J A;  3PM9 A;  1FIQ B;  4PVJ A;  2W54 A;  3EJB B;  3I99 A;  3POP A;  1V97 A;  2VAO A;  1W1O A;  2VFU A;  3S1D A;  3LAE A;  2BVF A;  1N61 C;  5AE1 A;  5K8E A;  4BBY A;  3GSY A;  1E8H A;  5AE3 A;  1E8F A;  3PQB A;  1VDV A;  5L6G A;  2VFV A;  1AHU A;  1DII A;  3SR6 B;  4BC9 A;  1FFU C;  4O95 A;  2QKN A;  4MLA A;  3W8X A;  2PLI A;  1FFV C;  2E3T A;  3B9J B;  3FW7 A;  3DED A;  5G5G B;  4PVH A;  4JAY A;  2QPM A;  3W8Z A;  2NQW A;  4UD8 A;  1WVE A;  4OAL A;  1W1K A;  5AE2 A;  3AM9 A;  1QLT A;  1FO4 A;  5HQX A;  3DQ0 A;  1ZXI C;  4EC3 A;  3C0P A;  5FXD A;  3D2H A;  3S1C A;  3ETR B;  5FXF A;  3FW9 A;  2WDW A;  2P4P A;  3W8W A;  2W3R A;  1MBT A;  3HRD C;  1W1S A;  2GQT A;  3HSU A;  1AHZ A;  1AHV A;  4PVE A;  3D2D A;  3NVY B;  1E0Y A;  2O3G A;  4ML8 A;  2W55 A;  2BVG A;  5ADZ A;  3AN1 A; 
#chains in the Genus database with same CATH homology
 2I0K A;  5I1W A;  1N63 C;  2VFR A;  1UXY A;  2GQU A;  4ZOH B;  1HSK A;  3FW8 A;  3TSH A;  3S1E A;  2R8D A;  3NVW B;  2BVH A;  1QLU A;  2VFS A;  3AMZ A;  3KJM A;  1WVF A;  4DNS A;  2R2Z A;  3RJ8 A;  2YVS A;  3TSJ A;  1DZN A;  1F0X A;  1N5X A;  2MBR A;  1W1M A;  1SB3 B;  2Y3R A;  1N62 C;  4JB1 A;  2Y08 A;  3LLB A;  4PWC A;  2W3S A;  2UUU A;  1W1Q A;  1W1R A;  2AXR A;  2P13 A;  4BC7 A;  2VFT A;  1W1L A;  1JRO A;  2UUV A;  2EXR A;  4PZF A;  1N5W C;  1VAO A;  1ZR6 A;  4XLO A;  3NVV B;  5AWV A;  3NS1 B;  5FXE A;  1N60 C;  2Y4G A;  4HG0 A;  4PYT A;  3TX1 A;  3EUB 3;  3NVZ B;  5D79 A;  2Q4W A;  1I19 A;  3BW7 A;  1T3Q C;  1JRP A;  5FXP A;  4PWB A;  3S1F A;  2IPI A;  1E8G A;  5HMR A;  2P3H A;  2OAI A;  2PLS A;  3D2J A;  1MBB A;  4BCA A;  2Y3S A;  4PVK A;  1DIQ A;  5L6F A;  3FWA A;  2RK5 A;  3JS8 A;  1RM6 B;  5HHZ A;  5G5H B;  5I1V A;  2Q85 A;  3RJA A;  3VTE A;  1WYG A;  3NRZ B;  1W1J A;  3PM9 A;  1FIQ B;  4PVJ A;  2W54 A;  3I99 A;  3POP A;  1V97 A;  2VAO A;  1W1O A;  2VFU A;  3S1D A;  3LAE A;  2BVF A;  1N61 C;  5AE1 A;  5K8E A;  4BBY A;  3GSY A;  1E8H A;  5AE3 A;  1E8F A;  3PQB A;  1VDV A;  5L6G A;  2VFV A;  1AHU A;  1DII A;  3SR6 B;  4BC9 A;  1FFU C;  4O95 A;  2QKN A;  4MLA A;  3W8X A;  2PLI A;  1FFV C;  2E3T A;  3B9J B;  3FW7 A;  3DED A;  5G5G B;  4PVH A;  4JAY A;  2QPM A;  3W8Z A;  2NQW A;  4UD8 A;  1WVE A;  4OAL A;  1W1K A;  5AE2 A;  3AM9 A;  1QLT A;  1FO4 A;  5HQX A;  3DQ0 A;  1ZXI C;  4EC3 A;  3C0P A;  5FXD A;  3D2H A;  3S1C A;  3ETR B;  5FXF A;  3FW9 A;  2WDW A;  2P4P A;  3W8W A;  2W3R A;  1MBT A;  3HRD C;  1W1S A;  2GQT A;  3HSU A;  1AHZ A;  1AHV A;  4PVE A;  3D2D A;  3NVY B;  1E0Y A;  2O3G A;  4ML8 A;  2W55 A;  2BVG A;  5ADZ A;  3AN1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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