2GQUA

Crystal structure of udp-n-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
266
structure length
266
Chain Sequence
FMRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQARAKDVLELVRRVQEELPLELEWEVWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-N-Acetylenolpyruvylglucosamine Reductase
publication title Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
pubmed doi rcsb
source organism Thermus caldophilus
molecule tags Oxidoreductase
total genus 79
structure length 266
sequence length 266
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2006-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2gquA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2gquA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2gquA03
1E0YA 1E8FA 2VFRA 1MBTA 4PVKA 2RK5A 1E8HA 2AXRA 3AM9A 5AE2A 1SB3B 4ZOHB 1W1QA 2BVGA 1AHUA 1W1OA 2BVHA 5FXFA 1QLTA 2QKNA 3BW7A 1W1JA 4MLAA 2VFVA 3B9JB 5FXPA 2W54A 3FW9A 1AHZA 4JAYA 5FXEA 1ZXIC 5FXDA 2BVFA 1AHVA 3JS8A 2GQTA 1W1LA 3NVWB 2EXRA 1E8GA 3KJMA 4JB1A 3SR6B 1DZNA 3NVZB 1N63C 2YVSA 3C0PA 2VAOA 3S1CA 3TX1A 2R8DA 1T3QC 4ML8A 3W8ZA 4OALA 5HQXA 2MBRA 5HMRA 4BC7A 1VDVA 2P3HA 3NS1B 1JRPA 5AE1A 2VFTA 1MBBA 3FWAA 5ADZA 2P13A 1N5XA 4UD8A 3S1FA 2NQWA 1N60C 1W1RA 1UXYA 2I0KA 1I19A 3AN1A 2GQUA 4XLOA 2O3GA 2OAIA 3NVYB 4O95A 3D2DA 3I99A 3TSHA 1N62C 1W1MA 3D2JA 3GSYA 4PVJA 4PVHA 4BCAA 1ZR6A 3LAEA 4EC3A 3FW8A 3TSJA 1RM6B 4PWBA 2PLIA 1N61C 3S1EA 4BC9A 2E3TA 4PVEA 2VFSA 2W3SA 2Q85A 3W8XA 3FW7A 3PM9A 3HRDC 3LLBA 2Q4WA 5G5HB 1V97A 1WVFA 3AMZA 1FIQB 1QLUA 4PYTA 1VAOA 2W55A 2P4PA 3ETRB 1FFVC 1DIQA 4HG0A 3D2HA 5AE3A 3S1DA 2QPMA 2VFUA 5HHZA 3DQ0A 1HSKA 1DIIA 3NRZB 1W1KA 1F0XA 3W8WA 2R2ZA 4BBYA 2W3RA 1N5WC 5G5GB 1FO4A 3EUB3 1FFUC 4PWCA 1WYGA 5D79A 1WVEA 1W1SA 4PZFA 4DNSA 2PLSA 3NVVB 3DEDA 3VTEA 1JROA
chains in the Genus database with same CATH superfamily
1E0YA 1E8FA 2VFRA 5L6FA 1MBTA 4PVKA 2RK5A 1E8HA 2AXRA 3AM9A 5AE2A 1SB3B 3EJEB 4ZOHB 2UUVA 1W1QA 2BVGA 1AHUA 1W1OA 2BVHA 5FXFA 1QLTA 2UUUA 2QKNA 3BW7A 1W1JA 4MLAA 2VFVA 3B9JB 3EJDB 5FXPA 2W54A 3FW9A 1AHZA 4JAYA 5FXEA 1ZXIC 5FXDA 2Y08A 2BVFA 1AHVA 3JS8A 2GQTA 1W1LA 3NVWB 2EXRA 1E8GA 3KJMA 4JB1A 3SR6B 2WDWA 1DZNA 3NVZB 1N63C 2YVSA 3C0PA 2VAOA 3S1CA 3TX1A 2R8DA 1T3QC 4ML8A 3W8ZA 4OALA 5HQXA 2MBRA 5HMRA 4BC7A 1VDVA 2P3HA 3NS1B 1JRPA 5AE1A 2VFTA 5I1WA 1MBBA 3FWAA 5ADZA 2Y3RA 2P13A 1N5XA 4UD8A 3S1FA 2NQWA 1N60C 1W1RA 2Y3SA 1UXYA 2I0KA 3HSUA 5AWVA 1I19A 3AN1A 2GQUA 4XLOA 2O3GA 2OAIA 3NVYB 4O95A 3D2DA 3I99A 3TSHA 1N62C 1W1MA 3D2JA 3GSYA 4PVJA 4PVHA 4BCAA 1ZR6A 3LAEA 4EC3A 3FW8A 3TSJA 1RM6B 4PWBA 2PLIA 1N61C 3S1EA 4BC9A 5I1VA 2E3TA 4PVEA 2VFSA 2W3SA 2Q85A 3W8XA 3FW7A 3PM9A 3HRDC 3LLBA 2Q4WA 5G5HB 1V97A 1WVFA 3AMZA 5K8EA 1FIQB 3RJ8A 1QLUA 4PYTA 2Y4GA 1VAOA 3POPA 2W55A 2P4PA 3ETRB 1FFVC 5L6GA 1DIQA 4HG0A 3D2HA 5AE3A 3S1DA 2QPMA 2VFUA 5HHZA 3DQ0A 1HSKA 1DIIA 3NRZB 1W1KA 1F0XA 3W8WA 2R2ZA 4BBYA 2W3RA 1N5WC 3RJAA 5G5GB 1FO4A 3EUB3 1FFUC 4PWCA 1WYGA 3EJBB 5D79A 1WVEA 1W1SA 4PZFA 4DNSA 3NVVB 2PLSA 3DEDA 2IPIA 3VTEA 1JROA 3PQBA
chains in the Genus database with same CATH topology
1E0YA 1E8FA 2VFRA 5L6FA 1MBTA 4PVKA 2RK5A 1E8HA 2AXRA 3AM9A 5AE2A 1SB3B 4ZOHB 2UUVA 1W1QA 2BVGA 1AHUA 1W1OA 2BVHA 5FXFA 1QLTA 2UUUA 2QKNA 3BW7A 1W1JA 4MLAA 2VFVA 3B9JB 5FXPA 2W54A 3FW9A 1AHZA 4JAYA 5FXEA 1ZXIC 5FXDA 2Y08A 2BVFA 1AHVA 3JS8A 2GQTA 1W1LA 3NVWB 2EXRA 1E8GA 3KJMA 4JB1A 3SR6B 2WDWA 1DZNA 3NVZB 1N63C 2YVSA 3C0PA 2VAOA 3S1CA 3TX1A 2R8DA 1T3QC 4ML8A 3W8ZA 4OALA 5HQXA 2MBRA 5HMRA 4BC7A 1VDVA 2P3HA 3NS1B 1JRPA 5AE1A 2VFTA 5I1WA 1MBBA 3FWAA 5ADZA 2Y3RA 2P13A 1N5XA 4UD8A 3S1FA 2NQWA 1N60C 1W1RA 2Y3SA 1UXYA 2I0KA 3HSUA 5AWVA 1I19A 3AN1A 2GQUA 4XLOA 2O3GA 2OAIA 3NVYB 4O95A 3D2DA 3I99A 3TSHA 1N62C 1W1MA 3D2JA 3GSYA 4PVJA 4PVHA 4BCAA 1ZR6A 3LAEA 4EC3A 3FW8A 3TSJA 1RM6B 4PWBA 2PLIA 1N61C 3S1EA 4BC9A 5I1VA 2E3TA 4PVEA 2VFSA 2W3SA 2Q85A 3W8XA 3FW7A 3PM9A 3HRDC 3LLBA 2Q4WA 5G5HB 1V97A 1WVFA 3AMZA 5K8EA 1FIQB 3RJ8A 1QLUA 4PYTA 2Y4GA 1VAOA 3POPA 2W55A 2P4PA 3ETRB 1FFVC 5L6GA 1DIQA 4HG0A 3D2HA 5AE3A 3S1DA 2QPMA 2VFUA 5HHZA 3DQ0A 1HSKA 1DIIA 3NRZB 1W1KA 1F0XA 3W8WA 2R2ZA 4BBYA 2W3RA 1N5WC 3RJAA 5G5GB 1FO4A 3EUB3 1FFUC 4PWCA 1WYGA 5D79A 1WVEA 1W1SA 4PZFA 4DNSA 2PLSA 3NVVB 3DEDA 2IPIA 3VTEA 1JROA 3PQBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E0Y A;  1E8F A;  2VFR A;  1MBT A;  4PVK A;  2RK5 A;  1E8H A;  2AXR A;  3AM9 A;  5AE2 A;  1SB3 B;  4ZOH B;  1W1Q A;  2BVG A;  1AHU A;  1W1O A;  2BVH A;  5FXF A;  1QLT A;  2QKN A;  3BW7 A;  1W1J A;  4MLA A;  2VFV A;  3B9J B;  5FXP A;  2W54 A;  3FW9 A;  1AHZ A;  4JAY A;  5FXE A;  1ZXI C;  5FXD A;  2BVF A;  1AHV A;  3JS8 A;  2GQT A;  1W1L A;  3NVW B;  2EXR A;  1E8G A;  3KJM A;  4JB1 A;  3SR6 B;  1DZN A;  3NVZ B;  1N63 C;  2YVS A;  3C0P A;  2VAO A;  3S1C A;  3TX1 A;  2R8D A;  1T3Q C;  4ML8 A;  3W8Z A;  4OAL A;  5HQX A;  2MBR A;  5HMR A;  4BC7 A;  1VDV A;  2P3H A;  3NS1 B;  1JRP A;  5AE1 A;  2VFT A;  1MBB A;  3FWA A;  5ADZ A;  2P13 A;  1N5X A;  4UD8 A;  3S1F A;  2NQW A;  1N60 C;  1W1R A;  1UXY A;  2I0K A;  1I19 A;  3AN1 A;  2GQU A;  4XLO A;  2O3G A;  2OAI A;  3NVY B;  4O95 A;  3D2D A;  3I99 A;  3TSH A;  1N62 C;  1W1M A;  3D2J A;  3GSY A;  4PVJ A;  4PVH A;  4BCA A;  1ZR6 A;  3LAE A;  4EC3 A;  3FW8 A;  3TSJ A;  1RM6 B;  4PWB A;  2PLI A;  1N61 C;  3S1E A;  4BC9 A;  2E3T A;  4PVE A;  2VFS A;  2W3S A;  2Q85 A;  3W8X A;  3FW7 A;  3PM9 A;  3HRD C;  3LLB A;  2Q4W A;  5G5H B;  1V97 A;  1WVF A;  3AMZ A;  1FIQ B;  1QLU A;  4PYT A;  1VAO A;  2W55 A;  2P4P A;  3ETR B;  1FFV C;  1DIQ A;  4HG0 A;  3D2H A;  5AE3 A;  3S1D A;  2QPM A;  2VFU A;  5HHZ A;  3DQ0 A;  1HSK A;  1DII A;  3NRZ B;  1W1K A;  1F0X A;  3W8W A;  2R2Z A;  4BBY A;  2W3R A;  1N5W C;  5G5G B;  1FO4 A;  3EUB 3;  1FFU C;  4PWC A;  1WYG A;  5D79 A;  1WVE A;  1W1S A;  4PZF A;  4DNS A;  2PLS A;  3NVV B;  3DED A;  3VTE A;  1JRO A; 
#chains in the Genus database with same CATH topology
 1E0Y A;  1E8F A;  2VFR A;  5L6F A;  1MBT A;  4PVK A;  2RK5 A;  1E8H A;  2AXR A;  3AM9 A;  5AE2 A;  1SB3 B;  3EJE B;  4ZOH B;  2UUV A;  1W1Q A;  2BVG A;  1AHU A;  1W1O A;  2BVH A;  5FXF A;  1QLT A;  2UUU A;  2QKN A;  3BW7 A;  1W1J A;  4MLA A;  2VFV A;  3B9J B;  3EJD B;  5FXP A;  2W54 A;  3FW9 A;  1AHZ A;  4JAY A;  5FXE A;  1ZXI C;  5FXD A;  2Y08 A;  2BVF A;  1AHV A;  3JS8 A;  2GQT A;  1W1L A;  3NVW B;  2EXR A;  1E8G A;  3KJM A;  4JB1 A;  3SR6 B;  2WDW A;  1DZN A;  3NVZ B;  1N63 C;  2YVS A;  3C0P A;  2VAO A;  3S1C A;  3TX1 A;  2R8D A;  1T3Q C;  4ML8 A;  3W8Z A;  4OAL A;  5HQX A;  2MBR A;  5HMR A;  4BC7 A;  1VDV A;  2P3H A;  3NS1 B;  1JRP A;  5AE1 A;  2VFT A;  5I1W A;  1MBB A;  3FWA A;  5ADZ A;  2Y3R A;  2P13 A;  1N5X A;  4UD8 A;  3S1F A;  2NQW A;  1N60 C;  1W1R A;  2Y3S A;  1UXY A;  2I0K A;  3HSU A;  5AWV A;  1I19 A;  3AN1 A;  2GQU A;  4XLO A;  2O3G A;  2OAI A;  3NVY B;  4O95 A;  3D2D A;  3I99 A;  3TSH A;  1N62 C;  1W1M A;  3D2J A;  3GSY A;  4PVJ A;  4PVH A;  4BCA A;  1ZR6 A;  3LAE A;  4EC3 A;  3FW8 A;  3TSJ A;  1RM6 B;  4PWB A;  2PLI A;  1N61 C;  3S1E A;  4BC9 A;  5I1V A;  2E3T A;  4PVE A;  2VFS A;  2W3S A;  2Q85 A;  3W8X A;  3FW7 A;  3PM9 A;  3HRD C;  3LLB A;  2Q4W A;  5G5H B;  1V97 A;  1WVF A;  3AMZ A;  5K8E A;  1FIQ B;  3RJ8 A;  1QLU A;  4PYT A;  2Y4G A;  1VAO A;  3POP A;  2W55 A;  2P4P A;  3ETR B;  1FFV C;  5L6G A;  1DIQ A;  4HG0 A;  3D2H A;  5AE3 A;  3S1D A;  2QPM A;  2VFU A;  5HHZ A;  3DQ0 A;  1HSK A;  1DII A;  3NRZ B;  1W1K A;  1F0X A;  3W8W A;  2R2Z A;  4BBY A;  2W3R A;  1N5W C;  3RJA A;  5G5G B;  1FO4 A;  3EUB 3;  1FFU C;  4PWC A;  1WYG A;  3EJB B;  5D79 A;  1WVE A;  1W1S A;  4PZF A;  4DNS A;  3NVV B;  2PLS A;  3DED A;  2IPI A;  3VTE A;  1JRO A;  3PQB A; 
#chains in the Genus database with same CATH homology
 1E0Y A;  1E8F A;  2VFR A;  5L6F A;  1MBT A;  4PVK A;  2RK5 A;  1E8H A;  2AXR A;  3AM9 A;  5AE2 A;  1SB3 B;  4ZOH B;  2UUV A;  1W1Q A;  2BVG A;  1AHU A;  1W1O A;  2BVH A;  5FXF A;  1QLT A;  2UUU A;  2QKN A;  3BW7 A;  1W1J A;  4MLA A;  2VFV A;  3B9J B;  5FXP A;  2W54 A;  3FW9 A;  1AHZ A;  4JAY A;  5FXE A;  1ZXI C;  5FXD A;  2Y08 A;  2BVF A;  1AHV A;  3JS8 A;  2GQT A;  1W1L A;  3NVW B;  2EXR A;  1E8G A;  3KJM A;  4JB1 A;  3SR6 B;  2WDW A;  1DZN A;  3NVZ B;  1N63 C;  2YVS A;  3C0P A;  2VAO A;  3S1C A;  3TX1 A;  2R8D A;  1T3Q C;  4ML8 A;  3W8Z A;  4OAL A;  5HQX A;  2MBR A;  5HMR A;  4BC7 A;  1VDV A;  2P3H A;  3NS1 B;  1JRP A;  5AE1 A;  2VFT A;  5I1W A;  1MBB A;  3FWA A;  5ADZ A;  2Y3R A;  2P13 A;  1N5X A;  4UD8 A;  3S1F A;  2NQW A;  1N60 C;  1W1R A;  2Y3S A;  1UXY A;  2I0K A;  3HSU A;  5AWV A;  1I19 A;  3AN1 A;  2GQU A;  4XLO A;  2O3G A;  2OAI A;  3NVY B;  4O95 A;  3D2D A;  3I99 A;  3TSH A;  1N62 C;  1W1M A;  3D2J A;  3GSY A;  4PVJ A;  4PVH A;  4BCA A;  1ZR6 A;  3LAE A;  4EC3 A;  3FW8 A;  3TSJ A;  1RM6 B;  4PWB A;  2PLI A;  1N61 C;  3S1E A;  4BC9 A;  5I1V A;  2E3T A;  4PVE A;  2VFS A;  2W3S A;  2Q85 A;  3W8X A;  3FW7 A;  3PM9 A;  3HRD C;  3LLB A;  2Q4W A;  5G5H B;  1V97 A;  1WVF A;  3AMZ A;  5K8E A;  1FIQ B;  3RJ8 A;  1QLU A;  4PYT A;  2Y4G A;  1VAO A;  3POP A;  2W55 A;  2P4P A;  3ETR B;  1FFV C;  5L6G A;  1DIQ A;  4HG0 A;  3D2H A;  5AE3 A;  3S1D A;  2QPM A;  2VFU A;  5HHZ A;  3DQ0 A;  1HSK A;  1DII A;  3NRZ B;  1W1K A;  1F0X A;  3W8W A;  2R2Z A;  4BBY A;  2W3R A;  1N5W C;  3RJA A;  5G5G B;  1FO4 A;  3EUB 3;  1FFU C;  4PWC A;  1WYG A;  5D79 A;  1WVE A;  1W1S A;  4PZF A;  4DNS A;  2PLS A;  3NVV B;  3DED A;  2IPI A;  3VTE A;  1JRO A;  3PQB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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