2GQUA

Crystal structure of udp-n-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
266
structure length
266
Chain Sequence
FMRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQARAKDVLELVRRVQEELPLELEWEVWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
pubmed doi rcsb
source organism Thermus caldophilus
molecule tags Oxidoreductase
molecule keywords UDP-N-Acetylenolpyruvylglucosamine Reductase
total genus 79
structure length 266
sequence length 266
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2006-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2gquA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2gquA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2gquA03
3FWAA 1W1SA 3LAEA 3AM9A 3TSHA 3NVWB 1FO4A 2OAIA 4O95A 2VFTA 2PLSA 4BC9A 3DEDA 2Q4WA 3NVVB 1WVFA 1QLTA 5FXPA 1AHVA 1FFVC 3SR6B 1W1LA 3KJMA 3W8XA 2GQTA 3I99A 2VFRA 1E8GA 1W1JA 5FXFA 5FXEA 1I19A 1DIQA 3FW9A 3S1EA 4PYTA 3BW7A 4OALA 1N61C 2NQWA 1E8FA 2W54A 1W1RA 1N62C 2P4PA 2EXRA 4XLOA 1ZXIC 3AMZA 4PVKA 1W1KA 3FW8A 5ADZA 3W8WA 1AHZA 1FIQB 2BVHA 1T3QC 2VFSA 2BVGA 2R8DA 1DIIA 3C0PA 1HSKA 1E8HA 4ML8A 5HQXA 1QLUA 4DNSA 3HRDC 3S1FA 3S1CA 1N63C 1JRPA 5G5GB 3NS1B 5AE3A 3TSJA 1FFUC 1SB3B 4EC3A 3PM9A 2W55A 1N60C 2AXRA 3DQ0A 4BCAA 3NRZB 4PZFA 2MBRA 5HHZA 3JS8A 4PWCA 4BBYA 1W1QA 1UXYA 3AN1A 1MBTA 5FXDA 2GQUA 2QPMA 3D2JA 3EUB3 5D79A 1W1MA 2I0KA 5AE1A 3D2HA 3FW7A 4MLAA 2P13A 4ZOHB 1W1OA 2R2ZA 1JROA 4UD8A 3S1DA 2YVSA 5G5HB 1MBBA 3NVZB 2BVFA 4PVEA 3B9JB 2O3GA 1E0YA 2P3HA 2PLIA 2VFUA 2VFVA 5AE2A 3NVYB 5HMRA 3LLBA 4BC7A 1ZR6A 3ETRB 3D2DA 2VAOA 2W3RA 2Q85A 1N5WC 1V97A 3GSYA 1AHUA 1VDVA 1WYGA 4JB1A 2QKNA 1WVEA 4PVJA 4PWBA 4HG0A 1N5XA 2W3SA 4PVHA 4JAYA 1VAOA 2E3TA 3W8ZA 2RK5A 1F0XA 1RM6B 3VTEA 3TX1A 1DZNA
chains in the Genus database with same CATH superfamily
3FWAA 1W1SA 3LAEA 3AM9A 2IPIA 3TSHA 3NVWB 1FO4A 2OAIA 4O95A 2VFTA 2PLSA 4BC9A 3DEDA 2Q4WA 3NVVB 3HSUA 1WVFA 2Y3RA 1QLTA 2WDWA 3PQBA 5K8EA 5FXPA 1AHVA 1FFVC 3SR6B 1W1LA 3KJMA 3W8XA 2GQTA 3I99A 2VFRA 1E8GA 1W1JA 5FXFA 5FXEA 1I19A 1DIQA 2UUVA 3FW9A 3S1EA 4PYTA 3BW7A 4OALA 1N61C 2NQWA 1E8FA 2W54A 1W1RA 1N62C 2P4PA 2EXRA 4XLOA 1ZXIC 3AMZA 4PVKA 3POPA 1W1KA 3FW8A 5ADZA 3W8WA 1AHZA 5L6GA 1FIQB 2BVHA 3EJDB 1T3QC 2VFSA 2BVGA 2R8DA 1DIIA 3C0PA 1HSKA 1E8HA 3EJEB 4ML8A 5HQXA 1QLUA 4DNSA 3HRDC 3S1FA 3S1CA 1N63C 1JRPA 5G5GB 3NS1B 5AE3A 3TSJA 1FFUC 1SB3B 4EC3A 3PM9A 2W55A 1N60C 2AXRA 3DQ0A 4BCAA 3NRZB 5I1VA 4PZFA 2MBRA 5HHZA 3JS8A 4PWCA 4BBYA 1W1QA 1UXYA 3AN1A 2Y3SA 1MBTA 5FXDA 2GQUA 2QPMA 2Y08A 3D2JA 3EUB3 5D79A 5AWVA 1W1MA 2I0KA 5AE1A 3D2HA 3FW7A 4MLAA 2P13A 4ZOHB 1W1OA 2R2ZA 2UUUA 1JROA 4UD8A 3S1DA 2YVSA 5G5HB 1MBBA 3NVZB 2BVFA 3EJBB 2Y4GA 4PVEA 3B9JB 2O3GA 1E0YA 2P3HA 2PLIA 3RJAA 3RJ8A 2VFUA 5I1WA 2VFVA 3NVYB 5AE2A 5HMRA 3LLBA 4BC7A 1ZR6A 3ETRB 5L6FA 3D2DA 2VAOA 2W3RA 2Q85A 1N5WC 1V97A 3GSYA 1AHUA 1VDVA 1WYGA 4JB1A 2QKNA 1WVEA 4PVJA 4PWBA 4HG0A 1N5XA 2W3SA 4PVHA 4JAYA 1VAOA 2E3TA 3W8ZA 2RK5A 1F0XA 1RM6B 3VTEA 3TX1A 1DZNA
chains in the Genus database with same CATH topology
3FWAA 1W1SA 3LAEA 3AM9A 2IPIA 3TSHA 3NVWB 1FO4A 2OAIA 4O95A 2VFTA 2PLSA 4BC9A 3DEDA 2Q4WA 3NVVB 3HSUA 1WVFA 2Y3RA 1QLTA 2WDWA 3PQBA 5K8EA 5FXPA 1AHVA 1FFVC 3SR6B 1W1LA 3KJMA 3W8XA 2GQTA 3I99A 2VFRA 1E8GA 1W1JA 5FXFA 5FXEA 1I19A 1DIQA 2UUVA 3FW9A 3S1EA 4PYTA 3BW7A 4OALA 1N61C 2NQWA 1E8FA 2W54A 1W1RA 1N62C 2P4PA 2EXRA 4XLOA 1ZXIC 3AMZA 4PVKA 3POPA 1W1KA 3FW8A 5ADZA 3W8WA 1AHZA 5L6GA 1FIQB 2BVHA 1T3QC 2VFSA 2BVGA 2R8DA 1DIIA 3C0PA 1HSKA 1E8HA 4ML8A 5HQXA 1QLUA 4DNSA 3HRDC 3S1FA 3S1CA 1N63C 1JRPA 5G5GB 3NS1B 5AE3A 3TSJA 1FFUC 1SB3B 4EC3A 3PM9A 2W55A 1N60C 2AXRA 3DQ0A 4BCAA 3NRZB 5I1VA 4PZFA 2MBRA 5HHZA 3JS8A 4PWCA 4BBYA 1W1QA 1UXYA 3AN1A 2Y3SA 1MBTA 5FXDA 2GQUA 2QPMA 2Y08A 3D2JA 3EUB3 5D79A 5AWVA 1W1MA 2I0KA 5AE1A 3D2HA 3FW7A 4MLAA 2P13A 4ZOHB 1W1OA 2R2ZA 2UUUA 1JROA 4UD8A 3S1DA 2YVSA 5G5HB 1MBBA 3NVZB 2BVFA 2Y4GA 4PVEA 3B9JB 2O3GA 1E0YA 2P3HA 2PLIA 3RJAA 3RJ8A 2VFUA 5I1WA 2VFVA 5AE2A 3NVYB 5HMRA 3LLBA 4BC7A 1ZR6A 3ETRB 5L6FA 3D2DA 2VAOA 2W3RA 2Q85A 1N5WC 1V97A 3GSYA 1AHUA 1VDVA 1WYGA 4JB1A 2QKNA 1WVEA 4PVJA 4PWBA 4HG0A 1N5XA 2W3SA 4PVHA 4JAYA 1VAOA 2E3TA 3W8ZA 2RK5A 1F0XA 1RM6B 3VTEA 3TX1A 1DZNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FWA A;  1W1S A;  3LAE A;  3AM9 A;  3TSH A;  3NVW B;  1FO4 A;  2OAI A;  4O95 A;  2VFT A;  2PLS A;  4BC9 A;  3DED A;  2Q4W A;  3NVV B;  1WVF A;  1QLT A;  5FXP A;  1AHV A;  1FFV C;  3SR6 B;  1W1L A;  3KJM A;  3W8X A;  2GQT A;  3I99 A;  2VFR A;  1E8G A;  1W1J A;  5FXF A;  5FXE A;  1I19 A;  1DIQ A;  3FW9 A;  3S1E A;  4PYT A;  3BW7 A;  4OAL A;  1N61 C;  2NQW A;  1E8F A;  2W54 A;  1W1R A;  1N62 C;  2P4P A;  2EXR A;  4XLO A;  1ZXI C;  3AMZ A;  4PVK A;  1W1K A;  3FW8 A;  5ADZ A;  3W8W A;  1AHZ A;  1FIQ B;  2BVH A;  1T3Q C;  2VFS A;  2BVG A;  2R8D A;  1DII A;  3C0P A;  1HSK A;  1E8H A;  4ML8 A;  5HQX A;  1QLU A;  4DNS A;  3HRD C;  3S1F A;  3S1C A;  1N63 C;  1JRP A;  5G5G B;  3NS1 B;  5AE3 A;  3TSJ A;  1FFU C;  1SB3 B;  4EC3 A;  3PM9 A;  2W55 A;  1N60 C;  2AXR A;  3DQ0 A;  4BCA A;  3NRZ B;  4PZF A;  2MBR A;  5HHZ A;  3JS8 A;  4PWC A;  4BBY A;  1W1Q A;  1UXY A;  3AN1 A;  1MBT A;  5FXD A;  2GQU A;  2QPM A;  3D2J A;  3EUB 3;  5D79 A;  1W1M A;  2I0K A;  5AE1 A;  3D2H A;  3FW7 A;  4MLA A;  2P13 A;  4ZOH B;  1W1O A;  2R2Z A;  1JRO A;  4UD8 A;  3S1D A;  2YVS A;  5G5H B;  1MBB A;  3NVZ B;  2BVF A;  4PVE A;  3B9J B;  2O3G A;  1E0Y A;  2P3H A;  2PLI A;  2VFU A;  2VFV A;  5AE2 A;  3NVY B;  5HMR A;  3LLB A;  4BC7 A;  1ZR6 A;  3ETR B;  3D2D A;  2VAO A;  2W3R A;  2Q85 A;  1N5W C;  1V97 A;  3GSY A;  1AHU A;  1VDV A;  1WYG A;  4JB1 A;  2QKN A;  1WVE A;  4PVJ A;  4PWB A;  4HG0 A;  1N5X A;  2W3S A;  4PVH A;  4JAY A;  1VAO A;  2E3T A;  3W8Z A;  2RK5 A;  1F0X A;  1RM6 B;  3VTE A;  3TX1 A;  1DZN A; 
#chains in the Genus database with same CATH topology
 3FWA A;  1W1S A;  3LAE A;  3AM9 A;  2IPI A;  3TSH A;  3NVW B;  1FO4 A;  2OAI A;  4O95 A;  2VFT A;  2PLS A;  4BC9 A;  3DED A;  2Q4W A;  3NVV B;  3HSU A;  1WVF A;  2Y3R A;  1QLT A;  2WDW A;  3PQB A;  5K8E A;  5FXP A;  1AHV A;  1FFV C;  3SR6 B;  1W1L A;  3KJM A;  3W8X A;  2GQT A;  3I99 A;  2VFR A;  1E8G A;  1W1J A;  5FXF A;  5FXE A;  1I19 A;  1DIQ A;  2UUV A;  3FW9 A;  3S1E A;  4PYT A;  3BW7 A;  4OAL A;  1N61 C;  2NQW A;  1E8F A;  2W54 A;  1W1R A;  1N62 C;  2P4P A;  2EXR A;  4XLO A;  1ZXI C;  3AMZ A;  4PVK A;  3POP A;  1W1K A;  3FW8 A;  5ADZ A;  3W8W A;  1AHZ A;  5L6G A;  1FIQ B;  2BVH A;  3EJD B;  1T3Q C;  2VFS A;  2BVG A;  2R8D A;  1DII A;  3C0P A;  1HSK A;  1E8H A;  3EJE B;  4ML8 A;  5HQX A;  1QLU A;  4DNS A;  3HRD C;  3S1F A;  3S1C A;  1N63 C;  1JRP A;  5G5G B;  3NS1 B;  5AE3 A;  3TSJ A;  1FFU C;  1SB3 B;  4EC3 A;  3PM9 A;  2W55 A;  1N60 C;  2AXR A;  3DQ0 A;  4BCA A;  3NRZ B;  5I1V A;  4PZF A;  2MBR A;  5HHZ A;  3JS8 A;  4PWC A;  4BBY A;  1W1Q A;  1UXY A;  3AN1 A;  2Y3S A;  1MBT A;  5FXD A;  2GQU A;  2QPM A;  2Y08 A;  3D2J A;  3EUB 3;  5D79 A;  5AWV A;  1W1M A;  2I0K A;  5AE1 A;  3D2H A;  3FW7 A;  4MLA A;  2P13 A;  4ZOH B;  1W1O A;  2R2Z A;  2UUU A;  1JRO A;  4UD8 A;  3S1D A;  2YVS A;  5G5H B;  1MBB A;  3NVZ B;  2BVF A;  3EJB B;  2Y4G A;  4PVE A;  3B9J B;  2O3G A;  1E0Y A;  2P3H A;  2PLI A;  3RJA A;  3RJ8 A;  2VFU A;  5I1W A;  2VFV A;  3NVY B;  5AE2 A;  5HMR A;  3LLB A;  4BC7 A;  1ZR6 A;  3ETR B;  5L6F A;  3D2D A;  2VAO A;  2W3R A;  2Q85 A;  1N5W C;  1V97 A;  3GSY A;  1AHU A;  1VDV A;  1WYG A;  4JB1 A;  2QKN A;  1WVE A;  4PVJ A;  4PWB A;  4HG0 A;  1N5X A;  2W3S A;  4PVH A;  4JAY A;  1VAO A;  2E3T A;  3W8Z A;  2RK5 A;  1F0X A;  1RM6 B;  3VTE A;  3TX1 A;  1DZN A; 
#chains in the Genus database with same CATH homology
 3FWA A;  1W1S A;  3LAE A;  3AM9 A;  2IPI A;  3TSH A;  3NVW B;  1FO4 A;  2OAI A;  4O95 A;  2VFT A;  2PLS A;  4BC9 A;  3DED A;  2Q4W A;  3NVV B;  3HSU A;  1WVF A;  2Y3R A;  1QLT A;  2WDW A;  3PQB A;  5K8E A;  5FXP A;  1AHV A;  1FFV C;  3SR6 B;  1W1L A;  3KJM A;  3W8X A;  2GQT A;  3I99 A;  2VFR A;  1E8G A;  1W1J A;  5FXF A;  5FXE A;  1I19 A;  1DIQ A;  2UUV A;  3FW9 A;  3S1E A;  4PYT A;  3BW7 A;  4OAL A;  1N61 C;  2NQW A;  1E8F A;  2W54 A;  1W1R A;  1N62 C;  2P4P A;  2EXR A;  4XLO A;  1ZXI C;  3AMZ A;  4PVK A;  3POP A;  1W1K A;  3FW8 A;  5ADZ A;  3W8W A;  1AHZ A;  5L6G A;  1FIQ B;  2BVH A;  1T3Q C;  2VFS A;  2BVG A;  2R8D A;  1DII A;  3C0P A;  1HSK A;  1E8H A;  4ML8 A;  5HQX A;  1QLU A;  4DNS A;  3HRD C;  3S1F A;  3S1C A;  1N63 C;  1JRP A;  5G5G B;  3NS1 B;  5AE3 A;  3TSJ A;  1FFU C;  1SB3 B;  4EC3 A;  3PM9 A;  2W55 A;  1N60 C;  2AXR A;  3DQ0 A;  4BCA A;  3NRZ B;  5I1V A;  4PZF A;  2MBR A;  5HHZ A;  3JS8 A;  4PWC A;  4BBY A;  1W1Q A;  1UXY A;  3AN1 A;  2Y3S A;  1MBT A;  5FXD A;  2GQU A;  2QPM A;  2Y08 A;  3D2J A;  3EUB 3;  5D79 A;  5AWV A;  1W1M A;  2I0K A;  5AE1 A;  3D2H A;  3FW7 A;  4MLA A;  2P13 A;  4ZOH B;  1W1O A;  2R2Z A;  2UUU A;  1JRO A;  4UD8 A;  3S1D A;  2YVS A;  5G5H B;  1MBB A;  3NVZ B;  2BVF A;  2Y4G A;  4PVE A;  3B9J B;  2O3G A;  1E0Y A;  2P3H A;  2PLI A;  3RJA A;  3RJ8 A;  2VFU A;  5I1W A;  2VFV A;  5AE2 A;  3NVY B;  5HMR A;  3LLB A;  4BC7 A;  1ZR6 A;  3ETR B;  5L6F A;  3D2D A;  2VAO A;  2W3R A;  2Q85 A;  1N5W C;  1V97 A;  3GSY A;  1AHU A;  1VDV A;  1WYG A;  4JB1 A;  2QKN A;  1WVE A;  4PVJ A;  4PWB A;  4HG0 A;  1N5X A;  2W3S A;  4PVH A;  4JAY A;  1VAO A;  2E3T A;  3W8Z A;  2RK5 A;  1F0X A;  1RM6 B;  3VTE A;  3TX1 A;  1DZN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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