2MBRA

Murb wild type, complex with enolpyruvyl-udp-n-acetylglucosamine
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
340
structure length
340
Chain Sequence
HSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE
total genus 105
structure length 340
sequence length 340
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 1996-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2mbrA02
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2mbrA03
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2mbrA01
2W54A 2GQTA 2OAIA 1UXYA 3TSHA 3EUB3 1FO4A 2VFUA 1W1OA 1W1SA 3FW7A 4HG0A 1N5XA 3FW8A 2RK5A 3DQ0A 3S1DA 1E0YA 5FXPA 4JAYA 1FFUC 1DZNA 3AM9A 4ZOHB 1ZR6A 5AE2A 1E8FA 3VTEA 3HRDC 2I0KA 3FW9A 3ETRB 1W1RA 3KJMA 1WYGA 3NVZB 3B9JB 5G5GB 2O3GA 2BVGA 4OALA 4PWBA 1N60C 1MBBA 3JS8A 3D2DA 4BBYA 3NS1B 3PM9A 2EXRA 1E8GA 1DIQA 3LLBA 1JROA 3C0PA 4JB1A 4UD8A 5AE3A 5G5HB 5FXDA 2P13A 4XLOA 1WVEA 1V97A 1W1LA 3AMZA 2E3TA 4DNSA 1W1JA 3W8WA 4EC3A 1I19A 5HMRA 3NVWB 2PLIA 4PYTA 4BC7A 2VAOA 1QLUA 4PVKA 1W1MA 1W1KA 3NVVB 2VFVA 4PVEA 2W55A 5HHZA 1N61C 2P4PA 1AHZA 5AE1A 2QKNA 2W3SA 2GQUA 3D2JA 5FXFA 2VFTA 5FXEA 3S1CA 1N62C 2QPMA 3BW7A 4PWCA 1VDVA 4PVHA 4BC9A 2VFRA 2P3HA 3D2HA 2R8DA 5ADZA 2YVSA 4BCAA 3W8ZA 2PLSA 3S1EA 1T3QC 2BVFA 1DIIA 1JRPA 3DEDA 1N63C 2Q4WA 4ML8A 1AHVA 1RM6B 1ZXIC 3NRZB 3TSJA 1F0XA 1MBTA 2NQWA 3AN1A 3GSYA 2VFSA 1FFVC 2MBRA 2BVHA 2AXRA 1FIQB 1W1QA 1SB3B 3SR6B 3TX1A 3S1FA 1VAOA 4MLAA 1QLTA 4O95A 3FWAA 2R2ZA 1N5WC 2W3RA 1HSKA 5HQXA 1WVFA 3I99A 3LAEA 1E8HA 3W8XA 4PZFA 2Q85A 1AHUA 5D79A 4PVJA 3NVYB
chains in the Genus database with same CATH superfamily
2W54A 2GQTA 2OAIA 3EJDB 1UXYA 3TSHA 3EUB3 1FO4A 2VFUA 1W1OA 1W1SA 3FW7A 4HG0A 1N5XA 3FW8A 2RK5A 3DQ0A 3S1DA 1E0YA 5FXPA 4JAYA 3RJAA 1FFUC 1DZNA 3AM9A 4ZOHB 1ZR6A 5AE2A 1E8FA 2WDWA 3VTEA 2Y4GA 3HRDC 2I0KA 3FW9A 3ETRB 2Y3RA 1W1RA 3KJMA 1WYGA 3NVZB 3B9JB 5G5GB 2IPIA 2O3GA 2BVGA 2UUUA 4OALA 4PWBA 1N60C 1MBBA 3JS8A 5K8EA 3D2DA 5L6FA 4BBYA 3NS1B 3PM9A 2EXRA 3HSUA 1E8GA 3POPA 1DIQA 3LLBA 1JROA 3C0PA 5L6GA 4JB1A 4UD8A 5AE3A 5G5HB 5FXDA 2P13A 5I1VA 4XLOA 1WVEA 1V97A 1W1LA 3AMZA 2E3TA 4DNSA 1W1JA 3W8WA 4EC3A 2Y3SA 1I19A 5HMRA 3NVWB 2PLIA 4PYTA 4BC7A 2VAOA 1QLUA 4PVKA 3PQBA 1W1MA 1W1KA 3NVVB 2VFVA 4PVEA 2W55A 5HHZA 1N61C 3EJEB 2P4PA 1AHZA 5AE1A 2QKNA 2W3SA 2GQUA 5I1WA 3D2JA 5FXFA 2VFTA 5FXEA 3S1CA 1N62C 2QPMA 3BW7A 4PWCA 1VDVA 4PVHA 4BC9A 2VFRA 2P3HA 3D2HA 2R8DA 5ADZA 2YVSA 4BCAA 5AWVA 3W8ZA 2Y08A 2PLSA 3S1EA 1T3QC 2BVFA 3EJBB 1DIIA 1JRPA 3DEDA 1N63C 2Q4WA 4ML8A 1AHVA 1RM6B 1ZXIC 3NRZB 3TSJA 1F0XA 1MBTA 2NQWA 3AN1A 3GSYA 2UUVA 2VFSA 1FFVC 2MBRA 2BVHA 2AXRA 1FIQB 1W1QA 1SB3B 3SR6B 3TX1A 3S1FA 1VAOA 4MLAA 1QLTA 4O95A 3FWAA 2R2ZA 1N5WC 2W3RA 1HSKA 5HQXA 1WVFA 3I99A 3LAEA 1E8HA 3RJ8A 3W8XA 4PZFA 2Q85A 1AHUA 5D79A 4PVJA 3NVYB
chains in the Genus database with same CATH topology
2W54A 2GQTA 2OAIA 1UXYA 3TSHA 3EUB3 1FO4A 2VFUA 1W1OA 1W1SA 3FW7A 4HG0A 1N5XA 3FW8A 2RK5A 3DQ0A 3S1DA 1E0YA 5FXPA 4JAYA 3RJAA 1FFUC 1DZNA 3AM9A 4ZOHB 1ZR6A 5AE2A 1E8FA 2WDWA 3VTEA 2Y4GA 3HRDC 2I0KA 3FW9A 3ETRB 2Y3RA 1W1RA 3KJMA 1WYGA 3NVZB 3B9JB 5G5GB 2IPIA 2O3GA 2BVGA 2UUUA 4OALA 4PWBA 1N60C 1MBBA 3JS8A 5K8EA 3D2DA 5L6FA 4BBYA 3NS1B 3PM9A 2EXRA 3HSUA 1E8GA 3POPA 1DIQA 3LLBA 1JROA 3C0PA 5L6GA 4JB1A 4UD8A 5AE3A 5G5HB 5FXDA 2P13A 5I1VA 4XLOA 1WVEA 1V97A 1W1LA 3AMZA 2E3TA 4DNSA 1W1JA 3W8WA 4EC3A 2Y3SA 1I19A 5HMRA 3NVWB 2PLIA 4PYTA 4BC7A 2VAOA 1QLUA 4PVKA 3PQBA 1W1MA 1W1KA 3NVVB 2VFVA 4PVEA 2W55A 5HHZA 1N61C 2P4PA 1AHZA 5AE1A 2QKNA 2W3SA 2GQUA 5I1WA 3D2JA 5FXFA 2VFTA 5FXEA 3S1CA 1N62C 2QPMA 3BW7A 4PWCA 1VDVA 4PVHA 4BC9A 2VFRA 2P3HA 3D2HA 2R8DA 5ADZA 2YVSA 4BCAA 5AWVA 3W8ZA 2Y08A 2PLSA 3S1EA 1T3QC 2BVFA 1DIIA 1JRPA 3DEDA 1N63C 2Q4WA 4ML8A 1AHVA 1RM6B 1ZXIC 3NRZB 3TSJA 1F0XA 1MBTA 2NQWA 3AN1A 3GSYA 2UUVA 2VFSA 1FFVC 2MBRA 2BVHA 2AXRA 1FIQB 1W1QA 1SB3B 3SR6B 3TX1A 3S1FA 1VAOA 4MLAA 1QLTA 4O95A 3FWAA 2R2ZA 1N5WC 2W3RA 1HSKA 5HQXA 1WVFA 3I99A 3LAEA 1E8HA 3RJ8A 3W8XA 4PZFA 2Q85A 1AHUA 5D79A 4PVJA 3NVYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W54 A;  2GQT A;  2OAI A;  1UXY A;  3TSH A;  3EUB 3;  1FO4 A;  2VFU A;  1W1O A;  1W1S A;  3FW7 A;  4HG0 A;  1N5X A;  3FW8 A;  2RK5 A;  3DQ0 A;  3S1D A;  1E0Y A;  5FXP A;  4JAY A;  1FFU C;  1DZN A;  3AM9 A;  4ZOH B;  1ZR6 A;  5AE2 A;  1E8F A;  3VTE A;  3HRD C;  2I0K A;  3FW9 A;  3ETR B;  1W1R A;  3KJM A;  1WYG A;  3NVZ B;  3B9J B;  5G5G B;  2O3G A;  2BVG A;  4OAL A;  4PWB A;  1N60 C;  1MBB A;  3JS8 A;  3D2D A;  4BBY A;  3NS1 B;  3PM9 A;  2EXR A;  1E8G A;  1DIQ A;  3LLB A;  1JRO A;  3C0P A;  4JB1 A;  4UD8 A;  5AE3 A;  5G5H B;  5FXD A;  2P13 A;  4XLO A;  1WVE A;  1V97 A;  1W1L A;  3AMZ A;  2E3T A;  4DNS A;  1W1J A;  3W8W A;  4EC3 A;  1I19 A;  5HMR A;  3NVW B;  2PLI A;  4PYT A;  4BC7 A;  2VAO A;  1QLU A;  4PVK A;  1W1M A;  1W1K A;  3NVV B;  2VFV A;  4PVE A;  2W55 A;  5HHZ A;  1N61 C;  2P4P A;  1AHZ A;  5AE1 A;  2QKN A;  2W3S A;  2GQU A;  3D2J A;  5FXF A;  2VFT A;  5FXE A;  3S1C A;  1N62 C;  2QPM A;  3BW7 A;  4PWC A;  1VDV A;  4PVH A;  4BC9 A;  2VFR A;  2P3H A;  3D2H A;  2R8D A;  5ADZ A;  2YVS A;  4BCA A;  3W8Z A;  2PLS A;  3S1E A;  1T3Q C;  2BVF A;  1DII A;  1JRP A;  3DED A;  1N63 C;  2Q4W A;  4ML8 A;  1AHV A;  1RM6 B;  1ZXI C;  3NRZ B;  3TSJ A;  1F0X A;  1MBT A;  2NQW A;  3AN1 A;  3GSY A;  2VFS A;  1FFV C;  2MBR A;  2BVH A;  2AXR A;  1FIQ B;  1W1Q A;  1SB3 B;  3SR6 B;  3TX1 A;  3S1F A;  1VAO A;  4MLA A;  1QLT A;  4O95 A;  3FWA A;  2R2Z A;  1N5W C;  2W3R A;  1HSK A;  5HQX A;  1WVF A;  3I99 A;  3LAE A;  1E8H A;  3W8X A;  4PZF A;  2Q85 A;  1AHU A;  5D79 A;  4PVJ A;  3NVY B; 
#chains in the Genus database with same CATH topology
 2W54 A;  2GQT A;  2OAI A;  3EJD B;  1UXY A;  3TSH A;  3EUB 3;  1FO4 A;  2VFU A;  1W1O A;  1W1S A;  3FW7 A;  4HG0 A;  1N5X A;  3FW8 A;  2RK5 A;  3DQ0 A;  3S1D A;  1E0Y A;  5FXP A;  4JAY A;  3RJA A;  1FFU C;  1DZN A;  3AM9 A;  4ZOH B;  1ZR6 A;  5AE2 A;  1E8F A;  2WDW A;  3VTE A;  2Y4G A;  3HRD C;  2I0K A;  3FW9 A;  3ETR B;  2Y3R A;  1W1R A;  3KJM A;  1WYG A;  3NVZ B;  3B9J B;  5G5G B;  2IPI A;  2O3G A;  2BVG A;  2UUU A;  4OAL A;  4PWB A;  1N60 C;  1MBB A;  3JS8 A;  5K8E A;  3D2D A;  5L6F A;  4BBY A;  3NS1 B;  3PM9 A;  2EXR A;  3HSU A;  1E8G A;  3POP A;  1DIQ A;  3LLB A;  1JRO A;  3C0P A;  5L6G A;  4JB1 A;  4UD8 A;  5AE3 A;  5G5H B;  5FXD A;  2P13 A;  5I1V A;  4XLO A;  1WVE A;  1V97 A;  1W1L A;  3AMZ A;  2E3T A;  4DNS A;  1W1J A;  3W8W A;  4EC3 A;  2Y3S A;  1I19 A;  5HMR A;  3NVW B;  2PLI A;  4PYT A;  4BC7 A;  2VAO A;  1QLU A;  4PVK A;  3PQB A;  1W1M A;  1W1K A;  3NVV B;  2VFV A;  4PVE A;  2W55 A;  5HHZ A;  1N61 C;  3EJE B;  2P4P A;  1AHZ A;  5AE1 A;  2QKN A;  2W3S A;  2GQU A;  5I1W A;  3D2J A;  5FXF A;  2VFT A;  5FXE A;  3S1C A;  1N62 C;  2QPM A;  3BW7 A;  4PWC A;  1VDV A;  4PVH A;  4BC9 A;  2VFR A;  2P3H A;  3D2H A;  2R8D A;  5ADZ A;  2YVS A;  4BCA A;  5AWV A;  3W8Z A;  2Y08 A;  2PLS A;  3S1E A;  1T3Q C;  2BVF A;  3EJB B;  1DII A;  1JRP A;  3DED A;  1N63 C;  2Q4W A;  4ML8 A;  1AHV A;  1RM6 B;  1ZXI C;  3NRZ B;  3TSJ A;  1F0X A;  1MBT A;  2NQW A;  3AN1 A;  3GSY A;  2UUV A;  2VFS A;  1FFV C;  2MBR A;  2BVH A;  2AXR A;  1FIQ B;  1W1Q A;  1SB3 B;  3SR6 B;  3TX1 A;  3S1F A;  1VAO A;  4MLA A;  1QLT A;  4O95 A;  3FWA A;  2R2Z A;  1N5W C;  2W3R A;  1HSK A;  5HQX A;  1WVF A;  3I99 A;  3LAE A;  1E8H A;  3RJ8 A;  3W8X A;  4PZF A;  2Q85 A;  1AHU A;  5D79 A;  4PVJ A;  3NVY B; 
#chains in the Genus database with same CATH homology
 2W54 A;  2GQT A;  2OAI A;  1UXY A;  3TSH A;  3EUB 3;  1FO4 A;  2VFU A;  1W1O A;  1W1S A;  3FW7 A;  4HG0 A;  1N5X A;  3FW8 A;  2RK5 A;  3DQ0 A;  3S1D A;  1E0Y A;  5FXP A;  4JAY A;  3RJA A;  1FFU C;  1DZN A;  3AM9 A;  4ZOH B;  1ZR6 A;  5AE2 A;  1E8F A;  2WDW A;  3VTE A;  2Y4G A;  3HRD C;  2I0K A;  3FW9 A;  3ETR B;  2Y3R A;  1W1R A;  3KJM A;  1WYG A;  3NVZ B;  3B9J B;  5G5G B;  2IPI A;  2O3G A;  2BVG A;  2UUU A;  4OAL A;  4PWB A;  1N60 C;  1MBB A;  3JS8 A;  5K8E A;  3D2D A;  5L6F A;  4BBY A;  3NS1 B;  3PM9 A;  2EXR A;  3HSU A;  1E8G A;  3POP A;  1DIQ A;  3LLB A;  1JRO A;  3C0P A;  5L6G A;  4JB1 A;  4UD8 A;  5AE3 A;  5G5H B;  5FXD A;  2P13 A;  5I1V A;  4XLO A;  1WVE A;  1V97 A;  1W1L A;  3AMZ A;  2E3T A;  4DNS A;  1W1J A;  3W8W A;  4EC3 A;  2Y3S A;  1I19 A;  5HMR A;  3NVW B;  2PLI A;  4PYT A;  4BC7 A;  2VAO A;  1QLU A;  4PVK A;  3PQB A;  1W1M A;  1W1K A;  3NVV B;  2VFV A;  4PVE A;  2W55 A;  5HHZ A;  1N61 C;  2P4P A;  1AHZ A;  5AE1 A;  2QKN A;  2W3S A;  2GQU A;  5I1W A;  3D2J A;  5FXF A;  2VFT A;  5FXE A;  3S1C A;  1N62 C;  2QPM A;  3BW7 A;  4PWC A;  1VDV A;  4PVH A;  4BC9 A;  2VFR A;  2P3H A;  3D2H A;  2R8D A;  5ADZ A;  2YVS A;  4BCA A;  5AWV A;  3W8Z A;  2Y08 A;  2PLS A;  3S1E A;  1T3Q C;  2BVF A;  1DII A;  1JRP A;  3DED A;  1N63 C;  2Q4W A;  4ML8 A;  1AHV A;  1RM6 B;  1ZXI C;  3NRZ B;  3TSJ A;  1F0X A;  1MBT A;  2NQW A;  3AN1 A;  3GSY A;  2UUV A;  2VFS A;  1FFV C;  2MBR A;  2BVH A;  2AXR A;  1FIQ B;  1W1Q A;  1SB3 B;  3SR6 B;  3TX1 A;  3S1F A;  1VAO A;  4MLA A;  1QLT A;  4O95 A;  3FWA A;  2R2Z A;  1N5W C;  2W3R A;  1HSK A;  5HQX A;  1WVF A;  3I99 A;  3LAE A;  1E8H A;  3RJ8 A;  3W8X A;  4PZF A;  2Q85 A;  1AHU A;  5D79 A;  4PVJ A;  3NVY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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