4PZFA

Berberine bridge enzyme g164a variant, a reticuline dehydrogenase
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
498
structure length
498
Chain Sequence
b'DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAAWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFD'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Reticuline oxidase
publication title Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.
pubmed doi rcsb
source organism Eschscholzia californica
molecule tags Oxidoreductase
total genus 163
structure length 498
sequence length 498
chains with identical sequence B, C, D
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2014-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4pzfA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4pzfA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4pzfA03
2VFRA 1N5WC 1E8GA 1N60C 3RJAA 1JROA 1WYGA 4PWCA 3S1FA 3W8XA 1E8FA 3S1CA 4BC7A 3S1EA 5I1VA 2WDWA 4XLOA 2W3RA 4UD8A 3TX1A 5AWVA 2VAOA 1W1KA 1WVFA 1MBTA 1E8HA 4BC9A 3ETRB 1W1JA 4PYTA 2GQUA 1N5XA 3POPA 1E0YA 1T3QC 3FWAA 2VFUA 4PVEA 5AE3A 3NVZB 5HMRA 5ADZA 3D2DA 4PWBA 3KJMA 1QLUA 3S1DA 5FXDA 2BVGA 1N61C 3EUB3 4MLAA 1HSKA 3B9JB 2W3SA 2IPIA 3NS1B 5L6GA 1W1OA 3RJ8A 4ML8A 4ZOHB 1AHUA 2Y08A 1DIIA 3PQBA 2Y3SA 3VTEA 1QLTA 5HHZA 2Q85A 5AE2A 3C0PA 2Y4GA 1W1SA 1DZNA 4JB1A 1F0XA 3PM9A 3HSUA 1DIQA 4PVKA 4EC3A 3D2JA 5HQXA 5K8EA 1ZXIC 3TSHA 4PZFA 5AE1A 3I99A 1W1MA 3W8WA 4BBYA 1UXYA 2I0KA 4PVHA 3TSJA 2W55A 3FW9A 3GSYA 5FXFA 2Q4WA 1WVEA 4BCAA 3AN1A 3NRZB 1MBBA 1W1LA 3AMZA 1VAOA 1AHVA 2QKNA 2W54A 4OALA 5FXEA 3FW8A 3FW7A 2Y3RA 1FFUC 3BW7A 2AXRA 1V97A 2E3TA 3JS8A 2MBRA 2BVHA 3DQ0A 1ZR6A 3D2HA 4JAYA 1FIQB 1VDVA 3AM9A 2BVFA 1W1RA 2VFTA 1N62C 2GQTA 2EXRA 2VFSA 4PVJA 1FFVC 2QPMA 3W8ZA 5D79A 1I19A 2VFVA 4O95A 3SR6B 5I1WA 1FO4A 1W1QA 4DNSA 1N63C 5L6FA 1AHZA 5FXPA
chains in the Genus database with same CATH superfamily
2VFRA 2YVSA 1N5WC 1E8GA 1N60C 3RJAA 1JROA 1WYGA 2PLIA 4PWCA 3S1FA 3W8XA 1E8FA 3S1CA 4BC7A 3S1EA 5I1VA 2WDWA 4XLOA 2W3RA 4UD8A 3TX1A 5AWVA 2VAOA 1W1KA 1WVFA 1MBTA 1E8HA 4BC9A 3ETRB 3LAEA 1W1JA 4PYTA 2GQUA 2OAIA 3NVWB 1N5XA 3POPA 1E0YA 1T3QC 3FWAA 2VFUA 4PVEA 5AE3A 3NVZB 5HMRA 4HG0A 5ADZA 3D2DA 4PWBA 3KJMA 1QLUA 3S1DA 5FXDA 2BVGA 1N61C 3EUB3 4MLAA 2NQWA 1HSKA 3B9JB 2W3SA 2IPIA 3NS1B 5L6GA 1W1OA 2PLSA 3RJ8A 4ML8A 4ZOHB 1AHUA 2Y08A 2UUUA 1DIIA 3PQBA 5G5HB 2Y3SA 3LLBA 3VTEA 1QLTA 5HHZA 3EJDB 3DEDA 2Q85A 5AE2A 3C0PA 2Y4GA 1W1SA 1DZNA 4JB1A 1F0XA 3PM9A 3HSUA 1DIQA 4PVKA 4EC3A 3D2JA 5HQXA 5K8EA 1ZXIC 3TSHA 5G5GB 4PZFA 5AE1A 2UUVA 3I99A 1W1MA 3W8WA 2P13A 2R2ZA 4BBYA 1UXYA 2I0KA 3NVYB 4PVHA 3TSJA 2W55A 3FW9A 3GSYA 5FXFA 2Q4WA 1WVEA 2P3HA 3EJBB 3AN1A 3NRZB 1MBBA 1W1LA 4BCAA 3AMZA 1SB3B 1VAOA 1AHVA 2QKNA 2W54A 4OALA 5FXEA 2R8DA 3FW8A 3FW7A 2O3GA 2Y3RA 1FFUC 2P4PA 3BW7A 2AXRA 3EJEB 1V97A 2E3TA 3JS8A 2MBRA 2BVHA 3DQ0A 1ZR6A 3D2HA 4JAYA 1FIQB 1VDVA 3AM9A 2BVFA 1W1RA 2VFTA 1JRPA 1N62C 2RK5A 3NVVB 2GQTA 2EXRA 2VFSA 4PVJA 1FFVC 2QPMA 3W8ZA 5D79A 1I19A 2VFVA 4O95A 3SR6B 5I1WA 3HRDC 1FO4A 1W1QA 4DNSA 1N63C 5L6FA 1RM6B 1AHZA 5FXPA
chains in the Genus database with same CATH topology
2VFRA 2YVSA 1N5WC 1E8GA 1N60C 3RJAA 1JROA 1WYGA 2PLIA 4PWCA 3S1FA 3W8XA 1E8FA 3S1CA 4BC7A 3S1EA 5I1VA 2WDWA 4XLOA 2W3RA 4UD8A 3TX1A 5AWVA 2VAOA 1W1KA 1WVFA 1MBTA 1E8HA 4BC9A 3ETRB 3LAEA 1W1JA 4PYTA 2GQUA 2OAIA 3NVWB 1N5XA 3POPA 1E0YA 1T3QC 3FWAA 2VFUA 4PVEA 5AE3A 3NVZB 5HMRA 4HG0A 5ADZA 3D2DA 4PWBA 3KJMA 1QLUA 3S1DA 5FXDA 2BVGA 1N61C 3EUB3 4MLAA 2NQWA 1HSKA 3B9JB 2W3SA 2IPIA 3NS1B 5L6GA 1W1OA 2PLSA 3RJ8A 4ML8A 4ZOHB 1AHUA 2Y08A 2UUUA 1DIIA 3PQBA 5G5HB 2Y3SA 3LLBA 3VTEA 1QLTA 5HHZA 3DEDA 2Q85A 5AE2A 3C0PA 2Y4GA 1W1SA 1DZNA 4JB1A 1F0XA 3PM9A 3HSUA 1DIQA 4PVKA 4EC3A 3D2JA 5HQXA 5K8EA 1ZXIC 3TSHA 5G5GB 4PZFA 5AE1A 2UUVA 3I99A 1W1MA 3W8WA 2P13A 2R2ZA 4BBYA 1UXYA 2I0KA 3NVYB 4PVHA 3TSJA 2W55A 3FW9A 3GSYA 5FXFA 2Q4WA 1WVEA 2P3HA 4BCAA 3AN1A 3NRZB 1MBBA 1W1LA 3AMZA 1SB3B 1VAOA 1AHVA 2QKNA 2W54A 4OALA 5FXEA 2R8DA 3FW8A 3FW7A 2O3GA 2Y3RA 1FFUC 2P4PA 3BW7A 2AXRA 1V97A 2E3TA 3JS8A 2MBRA 2BVHA 3DQ0A 1ZR6A 3D2HA 4JAYA 1FIQB 1VDVA 3AM9A 2BVFA 1W1RA 2VFTA 1JRPA 1N62C 2RK5A 3NVVB 2GQTA 2EXRA 2VFSA 4PVJA 1FFVC 2QPMA 3W8ZA 5D79A 1I19A 2VFVA 4O95A 3SR6B 5I1WA 3HRDC 1FO4A 1W1QA 4DNSA 1N63C 5L6FA 1RM6B 1AHZA 5FXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VFR A;  1N5W C;  1E8G A;  1N60 C;  3RJA A;  1JRO A;  1WYG A;  4PWC A;  3S1F A;  3W8X A;  1E8F A;  3S1C A;  4BC7 A;  3S1E A;  5I1V A;  2WDW A;  4XLO A;  2W3R A;  4UD8 A;  3TX1 A;  5AWV A;  2VAO A;  1W1K A;  1WVF A;  1MBT A;  1E8H A;  4BC9 A;  3ETR B;  1W1J A;  4PYT A;  2GQU A;  1N5X A;  3POP A;  1E0Y A;  1T3Q C;  3FWA A;  2VFU A;  4PVE A;  5AE3 A;  3NVZ B;  5HMR A;  5ADZ A;  3D2D A;  4PWB A;  3KJM A;  1QLU A;  3S1D A;  5FXD A;  2BVG A;  1N61 C;  3EUB 3;  4MLA A;  1HSK A;  3B9J B;  2W3S A;  2IPI A;  3NS1 B;  5L6G A;  1W1O A;  3RJ8 A;  4ML8 A;  4ZOH B;  1AHU A;  2Y08 A;  1DII A;  3PQB A;  2Y3S A;  3VTE A;  1QLT A;  5HHZ A;  2Q85 A;  5AE2 A;  3C0P A;  2Y4G A;  1W1S A;  1DZN A;  4JB1 A;  1F0X A;  3PM9 A;  3HSU A;  1DIQ A;  4PVK A;  4EC3 A;  3D2J A;  5HQX A;  5K8E A;  1ZXI C;  3TSH A;  4PZF A;  5AE1 A;  3I99 A;  1W1M A;  3W8W A;  4BBY A;  1UXY A;  2I0K A;  4PVH A;  3TSJ A;  2W55 A;  3FW9 A;  3GSY A;  5FXF A;  2Q4W A;  1WVE A;  4BCA A;  3AN1 A;  3NRZ B;  1MBB A;  1W1L A;  3AMZ A;  1VAO A;  1AHV A;  2QKN A;  2W54 A;  4OAL A;  5FXE A;  3FW8 A;  3FW7 A;  2Y3R A;  1FFU C;  3BW7 A;  2AXR A;  1V97 A;  2E3T A;  3JS8 A;  2MBR A;  2BVH A;  3DQ0 A;  1ZR6 A;  3D2H A;  4JAY A;  1FIQ B;  1VDV A;  3AM9 A;  2BVF A;  1W1R A;  2VFT A;  1N62 C;  2GQT A;  2EXR A;  2VFS A;  4PVJ A;  1FFV C;  2QPM A;  3W8Z A;  5D79 A;  1I19 A;  2VFV A;  4O95 A;  3SR6 B;  5I1W A;  1FO4 A;  1W1Q A;  4DNS A;  1N63 C;  5L6F A;  1AHZ A;  5FXP A; 
#chains in the Genus database with same CATH topology
 2VFR A;  2YVS A;  1N5W C;  1E8G A;  1N60 C;  3RJA A;  1JRO A;  1WYG A;  2PLI A;  4PWC A;  3S1F A;  3W8X A;  1E8F A;  3S1C A;  4BC7 A;  3S1E A;  5I1V A;  2WDW A;  4XLO A;  2W3R A;  4UD8 A;  3TX1 A;  5AWV A;  2VAO A;  1W1K A;  1WVF A;  1MBT A;  1E8H A;  4BC9 A;  3ETR B;  3LAE A;  1W1J A;  4PYT A;  2GQU A;  2OAI A;  3NVW B;  1N5X A;  3POP A;  1E0Y A;  1T3Q C;  3FWA A;  2VFU A;  4PVE A;  5AE3 A;  3NVZ B;  5HMR A;  4HG0 A;  5ADZ A;  3D2D A;  4PWB A;  3KJM A;  1QLU A;  3S1D A;  5FXD A;  2BVG A;  1N61 C;  3EUB 3;  4MLA A;  2NQW A;  1HSK A;  3B9J B;  2W3S A;  2IPI A;  3NS1 B;  5L6G A;  1W1O A;  2PLS A;  3RJ8 A;  4ML8 A;  4ZOH B;  1AHU A;  2Y08 A;  2UUU A;  1DII A;  3PQB A;  5G5H B;  2Y3S A;  3LLB A;  3VTE A;  1QLT A;  5HHZ A;  3EJD B;  3DED A;  2Q85 A;  5AE2 A;  3C0P A;  2Y4G A;  1W1S A;  1DZN A;  4JB1 A;  1F0X A;  3PM9 A;  3HSU A;  1DIQ A;  4PVK A;  4EC3 A;  3D2J A;  5HQX A;  5K8E A;  1ZXI C;  3TSH A;  5G5G B;  4PZF A;  5AE1 A;  2UUV A;  3I99 A;  1W1M A;  3W8W A;  2P13 A;  2R2Z A;  4BBY A;  1UXY A;  2I0K A;  3NVY B;  4PVH A;  3TSJ A;  2W55 A;  3FW9 A;  3GSY A;  5FXF A;  2Q4W A;  1WVE A;  2P3H A;  3EJB B;  3AN1 A;  3NRZ B;  1MBB A;  1W1L A;  4BCA A;  3AMZ A;  1SB3 B;  1VAO A;  1AHV A;  2QKN A;  2W54 A;  4OAL A;  5FXE A;  2R8D A;  3FW8 A;  3FW7 A;  2O3G A;  2Y3R A;  1FFU C;  2P4P A;  3BW7 A;  2AXR A;  3EJE B;  1V97 A;  2E3T A;  3JS8 A;  2MBR A;  2BVH A;  3DQ0 A;  1ZR6 A;  3D2H A;  4JAY A;  1FIQ B;  1VDV A;  3AM9 A;  2BVF A;  1W1R A;  2VFT A;  1JRP A;  1N62 C;  2RK5 A;  3NVV B;  2GQT A;  2EXR A;  2VFS A;  4PVJ A;  1FFV C;  2QPM A;  3W8Z A;  5D79 A;  1I19 A;  2VFV A;  4O95 A;  3SR6 B;  5I1W A;  3HRD C;  1FO4 A;  1W1Q A;  4DNS A;  1N63 C;  5L6F A;  1RM6 B;  1AHZ A;  5FXP A; 
#chains in the Genus database with same CATH homology
 2VFR A;  2YVS A;  1N5W C;  1E8G A;  1N60 C;  3RJA A;  1JRO A;  1WYG A;  2PLI A;  4PWC A;  3S1F A;  3W8X A;  1E8F A;  3S1C A;  4BC7 A;  3S1E A;  5I1V A;  2WDW A;  4XLO A;  2W3R A;  4UD8 A;  3TX1 A;  5AWV A;  2VAO A;  1W1K A;  1WVF A;  1MBT A;  1E8H A;  4BC9 A;  3ETR B;  3LAE A;  1W1J A;  4PYT A;  2GQU A;  2OAI A;  3NVW B;  1N5X A;  3POP A;  1E0Y A;  1T3Q C;  3FWA A;  2VFU A;  4PVE A;  5AE3 A;  3NVZ B;  5HMR A;  4HG0 A;  5ADZ A;  3D2D A;  4PWB A;  3KJM A;  1QLU A;  3S1D A;  5FXD A;  2BVG A;  1N61 C;  3EUB 3;  4MLA A;  2NQW A;  1HSK A;  3B9J B;  2W3S A;  2IPI A;  3NS1 B;  5L6G A;  1W1O A;  2PLS A;  3RJ8 A;  4ML8 A;  4ZOH B;  1AHU A;  2Y08 A;  2UUU A;  1DII A;  3PQB A;  5G5H B;  2Y3S A;  3LLB A;  3VTE A;  1QLT A;  5HHZ A;  3DED A;  2Q85 A;  5AE2 A;  3C0P A;  2Y4G A;  1W1S A;  1DZN A;  4JB1 A;  1F0X A;  3PM9 A;  3HSU A;  1DIQ A;  4PVK A;  4EC3 A;  3D2J A;  5HQX A;  5K8E A;  1ZXI C;  3TSH A;  5G5G B;  4PZF A;  5AE1 A;  2UUV A;  3I99 A;  1W1M A;  3W8W A;  2P13 A;  2R2Z A;  4BBY A;  1UXY A;  2I0K A;  3NVY B;  4PVH A;  3TSJ A;  2W55 A;  3FW9 A;  3GSY A;  5FXF A;  2Q4W A;  1WVE A;  2P3H A;  4BCA A;  3AN1 A;  3NRZ B;  1MBB A;  1W1L A;  3AMZ A;  1SB3 B;  1VAO A;  1AHV A;  2QKN A;  2W54 A;  4OAL A;  5FXE A;  2R8D A;  3FW8 A;  3FW7 A;  2O3G A;  2Y3R A;  1FFU C;  2P4P A;  3BW7 A;  2AXR A;  1V97 A;  2E3T A;  3JS8 A;  2MBR A;  2BVH A;  3DQ0 A;  1ZR6 A;  3D2H A;  4JAY A;  1FIQ B;  1VDV A;  3AM9 A;  2BVF A;  1W1R A;  2VFT A;  1JRP A;  1N62 C;  2RK5 A;  3NVV B;  2GQT A;  2EXR A;  2VFS A;  4PVJ A;  1FFV C;  2QPM A;  3W8Z A;  5D79 A;  1I19 A;  2VFV A;  4O95 A;  3SR6 B;  5I1W A;  3HRD C;  1FO4 A;  1W1Q A;  4DNS A;  1N63 C;  5L6F A;  1RM6 B;  1AHZ A;  5FXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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