4PZFA

Berberine bridge enzyme g164a variant, a reticuline dehydrogenase
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
498
structure length
498
Chain Sequence
DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAAWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.
pubmed doi rcsb
source organism Eschscholzia californica
molecule tags Oxidoreductase
molecule keywords Reticuline oxidase
total genus 163
structure length 498
sequence length 498
chains with identical sequence B, C, D
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2014-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4pzfA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4pzfA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4pzfA03
3W8XA 5AE1A 3EUB3 4PVJA 3FWAA 1HSKA 2W3RA 4UD8A 1E8HA 1MBBA 1AHUA 1T3QC 3JS8A 2VFTA 1DIQA 1DZNA 2BVFA 1QLUA 5I1WA 1W1SA 1ZR6A 3D2DA 3C0PA 3RJ8A 4ML8A 5ADZA 1N5WC 3D2JA 2GQUA 1VAOA 4DNSA 2EXRA 3W8ZA 2QPMA 3PM9A 3NRZB 4PYTA 1E8GA 3RJAA 5K8EA 5FXPA 1W1LA 4PWCA 2AXRA 4PZFA 1QLTA 1FO4A 3FW8A 2VFVA 1AHVA 3TX1A 1VDVA 4BBYA 2E3TA 1F0XA 4PVKA 1WVEA 3AMZA 1FIQB 2BVGA 1W1KA 3HSUA 1N60C 2W3SA 2I0KA 1WYGA 3FW9A 3DQ0A 2BVHA 1WVFA 3BW7A 1E8FA 5HQXA 2IPIA 2Y4GA 1N62C 4PVEA 2WDWA 3POPA 4XLOA 2Y08A 5FXFA 3W8WA 4BC9A 3AM9A 3ETRB 3S1EA 3S1FA 3KJMA 1W1OA 5AE2A 2Y3RA 2Q85A 3NVZB 3S1CA 1UXYA 3I99A 1E0YA 4JAYA 4OALA 5D79A 2W54A 1W1RA 1AHZA 2QKNA 3TSHA 5HMRA 3PQBA 5AWVA 3GSYA 4PVHA 1FFUC 4JB1A 2Y3SA 2VFUA 3S1DA 1N61C 4BCAA 3VTEA 1MBTA 1JROA 2MBRA 5L6FA 5FXEA 5I1VA 3B9JB 4PWBA 2GQTA 3D2HA 5FXDA 1ZXIC 2VFSA 2VAOA 5L6GA 1W1MA 2VFRA 3SR6B 5HHZA 1N63C 2W55A 3FW7A 4O95A 5AE3A 4MLAA 3AN1A 1FFVC 1I19A 1V97A 3TSJA 3NS1B 1W1JA 4ZOHB 1W1QA 4EC3A 2Q4WA 1DIIA 1N5XA 4BC7A
chains in the Genus database with same CATH superfamily
3W8XA 5AE1A 3EUB3 4PVJA 3NVWB 3FWAA 1HSKA 2W3RA 4UD8A 1E8HA 1MBBA 1AHUA 1T3QC 2PLIA 3JS8A 2R2ZA 3LAEA 2VFTA 2P4PA 1DIQA 1DZNA 2BVFA 1QLUA 5I1WA 1W1SA 1ZR6A 3D2DA 3C0PA 3RJ8A 4ML8A 5ADZA 1N5WC 3D2JA 2GQUA 1VAOA 4DNSA 2UUVA 2EXRA 3W8ZA 2QPMA 3PM9A 3NRZB 4PYTA 1E8GA 3RJAA 5K8EA 1RM6B 5FXPA 1W1LA 4PWCA 2AXRA 3EJEB 4PZFA 1QLTA 1FO4A 3FW8A 2VFVA 2YVSA 1AHVA 3TX1A 1VDVA 4BBYA 2E3TA 3EJBB 1F0XA 4PVKA 2P3HA 1WVEA 3AMZA 1FIQB 2BVGA 1W1KA 4HG0A 3HSUA 1N60C 2W3SA 2I0KA 2UUUA 1WYGA 3FW9A 3DQ0A 2BVHA 1WVFA 1JRPA 3BW7A 1E8FA 5HQXA 2IPIA 2Y4GA 1N62C 4PVEA 5G5HB 2WDWA 3POPA 4XLOA 2Y08A 5FXFA 3W8WA 4BC9A 3AM9A 1SB3B 3ETRB 3S1EA 3S1FA 3KJMA 1W1OA 5AE2A 2Y3RA 2Q85A 3NVZB 3S1CA 1UXYA 3I99A 1E0YA 4JAYA 4OALA 5D79A 2W54A 1W1RA 2RK5A 1AHZA 2QKNA 3LLBA 3TSHA 5HMRA 3PQBA 5AWVA 3GSYA 4PVHA 2NQWA 1FFUC 4JB1A 2Y3SA 2VFUA 3S1DA 1N61C 2R8DA 4BCAA 3HRDC 3VTEA 2OAIA 1MBTA 1JROA 2MBRA 2PLSA 5FXEA 5L6FA 3NVVB 5I1VA 3B9JB 4PWBA 2GQTA 2O3GA 3D2HA 5FXDA 1ZXIC 5G5GB 2VFSA 2VAOA 5L6GA 1W1MA 2VFRA 3SR6B 5HHZA 1N63C 3EJDB 2W55A 3FW7A 3NVYB 4O95A 5AE3A 2P13A 3DEDA 4MLAA 3AN1A 1FFVC 1I19A 1V97A 3TSJA 3NS1B 1W1JA 4ZOHB 1W1QA 4EC3A 2Q4WA 1DIIA 1N5XA 4BC7A
chains in the Genus database with same CATH topology
3W8XA 5AE1A 3EUB3 4PVJA 3NVWB 3FWAA 1HSKA 2W3RA 4UD8A 1E8HA 1MBBA 1AHUA 1T3QC 2PLIA 3JS8A 2R2ZA 3LAEA 2VFTA 2P4PA 1DIQA 1DZNA 2BVFA 1QLUA 5I1WA 1W1SA 1ZR6A 3D2DA 3C0PA 3RJ8A 4ML8A 5ADZA 1N5WC 3D2JA 2GQUA 1VAOA 4DNSA 2UUVA 2EXRA 3W8ZA 2QPMA 3PM9A 3NRZB 4PYTA 1E8GA 3RJAA 5K8EA 1RM6B 5FXPA 1W1LA 4PWCA 2AXRA 4PZFA 1QLTA 1FO4A 3FW8A 2VFVA 2YVSA 1AHVA 3TX1A 1VDVA 4BBYA 2E3TA 1F0XA 4PVKA 2P3HA 1WVEA 3AMZA 1FIQB 2BVGA 1W1KA 4HG0A 3HSUA 1N60C 2W3SA 2I0KA 2UUUA 1WYGA 3FW9A 3DQ0A 2BVHA 1WVFA 1JRPA 3BW7A 1E8FA 5HQXA 2IPIA 2Y4GA 1N62C 4PVEA 5G5HB 2WDWA 3POPA 4XLOA 2Y08A 5FXFA 3W8WA 4BC9A 3AM9A 1SB3B 3ETRB 3S1EA 3S1FA 3KJMA 1W1OA 5AE2A 2Y3RA 2Q85A 3NVZB 3S1CA 1UXYA 3I99A 1E0YA 4JAYA 4OALA 5D79A 2W54A 1W1RA 2RK5A 1AHZA 2QKNA 3LLBA 3TSHA 5HMRA 3PQBA 5AWVA 3GSYA 4PVHA 2NQWA 1FFUC 4JB1A 2Y3SA 2VFUA 3S1DA 1N61C 2R8DA 4BCAA 3HRDC 3VTEA 2OAIA 1MBTA 1JROA 2MBRA 2PLSA 5FXEA 5L6FA 3NVVB 5I1VA 3B9JB 4PWBA 2GQTA 2O3GA 3D2HA 5FXDA 1ZXIC 5G5GB 2VFSA 2VAOA 5L6GA 1W1MA 2VFRA 3SR6B 5HHZA 1N63C 2W55A 3FW7A 3NVYB 4O95A 5AE3A 2P13A 3DEDA 4MLAA 3AN1A 1FFVC 1I19A 1V97A 3TSJA 3NS1B 1W1JA 4ZOHB 1W1QA 4EC3A 2Q4WA 1DIIA 1N5XA 4BC7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8X A;  5AE1 A;  3EUB 3;  4PVJ A;  3FWA A;  1HSK A;  2W3R A;  4UD8 A;  1E8H A;  1MBB A;  1AHU A;  1T3Q C;  3JS8 A;  2VFT A;  1DIQ A;  1DZN A;  2BVF A;  1QLU A;  5I1W A;  1W1S A;  1ZR6 A;  3D2D A;  3C0P A;  3RJ8 A;  4ML8 A;  5ADZ A;  1N5W C;  3D2J A;  2GQU A;  1VAO A;  4DNS A;  2EXR A;  3W8Z A;  2QPM A;  3PM9 A;  3NRZ B;  4PYT A;  1E8G A;  3RJA A;  5K8E A;  5FXP A;  1W1L A;  4PWC A;  2AXR A;  4PZF A;  1QLT A;  1FO4 A;  3FW8 A;  2VFV A;  1AHV A;  3TX1 A;  1VDV A;  4BBY A;  2E3T A;  1F0X A;  4PVK A;  1WVE A;  3AMZ A;  1FIQ B;  2BVG A;  1W1K A;  3HSU A;  1N60 C;  2W3S A;  2I0K A;  1WYG A;  3FW9 A;  3DQ0 A;  2BVH A;  1WVF A;  3BW7 A;  1E8F A;  5HQX A;  2IPI A;  2Y4G A;  1N62 C;  4PVE A;  2WDW A;  3POP A;  4XLO A;  2Y08 A;  5FXF A;  3W8W A;  4BC9 A;  3AM9 A;  3ETR B;  3S1E A;  3S1F A;  3KJM A;  1W1O A;  5AE2 A;  2Y3R A;  2Q85 A;  3NVZ B;  3S1C A;  1UXY A;  3I99 A;  1E0Y A;  4JAY A;  4OAL A;  5D79 A;  2W54 A;  1W1R A;  1AHZ A;  2QKN A;  3TSH A;  5HMR A;  3PQB A;  5AWV A;  3GSY A;  4PVH A;  1FFU C;  4JB1 A;  2Y3S A;  2VFU A;  3S1D A;  1N61 C;  4BCA A;  3VTE A;  1MBT A;  1JRO A;  2MBR A;  5L6F A;  5FXE A;  5I1V A;  3B9J B;  4PWB A;  2GQT A;  3D2H A;  5FXD A;  1ZXI C;  2VFS A;  2VAO A;  5L6G A;  1W1M A;  2VFR A;  3SR6 B;  5HHZ A;  1N63 C;  2W55 A;  3FW7 A;  4O95 A;  5AE3 A;  4MLA A;  3AN1 A;  1FFV C;  1I19 A;  1V97 A;  3TSJ A;  3NS1 B;  1W1J A;  4ZOH B;  1W1Q A;  4EC3 A;  2Q4W A;  1DII A;  1N5X A;  4BC7 A; 
#chains in the Genus database with same CATH topology
 3W8X A;  5AE1 A;  3EUB 3;  4PVJ A;  3NVW B;  3FWA A;  1HSK A;  2W3R A;  4UD8 A;  1E8H A;  1MBB A;  1AHU A;  1T3Q C;  2PLI A;  3JS8 A;  2R2Z A;  3LAE A;  2VFT A;  2P4P A;  1DIQ A;  1DZN A;  2BVF A;  1QLU A;  5I1W A;  1W1S A;  1ZR6 A;  3D2D A;  3C0P A;  3RJ8 A;  4ML8 A;  5ADZ A;  1N5W C;  3D2J A;  2GQU A;  1VAO A;  4DNS A;  2UUV A;  2EXR A;  3W8Z A;  2QPM A;  3PM9 A;  3NRZ B;  4PYT A;  1E8G A;  3RJA A;  5K8E A;  1RM6 B;  5FXP A;  1W1L A;  4PWC A;  2AXR A;  3EJE B;  4PZF A;  1QLT A;  1FO4 A;  3FW8 A;  2VFV A;  2YVS A;  1AHV A;  3TX1 A;  1VDV A;  4BBY A;  2E3T A;  3EJB B;  1F0X A;  4PVK A;  2P3H A;  1WVE A;  3AMZ A;  1FIQ B;  2BVG A;  1W1K A;  4HG0 A;  3HSU A;  1N60 C;  2W3S A;  2I0K A;  2UUU A;  1WYG A;  3FW9 A;  3DQ0 A;  2BVH A;  1WVF A;  1JRP A;  3BW7 A;  1E8F A;  5HQX A;  2IPI A;  2Y4G A;  1N62 C;  4PVE A;  5G5H B;  2WDW A;  3POP A;  4XLO A;  2Y08 A;  5FXF A;  3W8W A;  4BC9 A;  3AM9 A;  1SB3 B;  3ETR B;  3S1E A;  3S1F A;  3KJM A;  1W1O A;  5AE2 A;  2Y3R A;  2Q85 A;  3NVZ B;  3S1C A;  1UXY A;  3I99 A;  1E0Y A;  4JAY A;  4OAL A;  5D79 A;  2W54 A;  1W1R A;  2RK5 A;  1AHZ A;  2QKN A;  3LLB A;  3TSH A;  5HMR A;  3PQB A;  5AWV A;  3GSY A;  4PVH A;  2NQW A;  1FFU C;  4JB1 A;  2Y3S A;  2VFU A;  3S1D A;  1N61 C;  2R8D A;  4BCA A;  3HRD C;  3VTE A;  2OAI A;  1MBT A;  1JRO A;  2MBR A;  2PLS A;  5FXE A;  5L6F A;  3NVV B;  5I1V A;  3B9J B;  4PWB A;  2GQT A;  2O3G A;  3D2H A;  5FXD A;  1ZXI C;  5G5G B;  2VFS A;  2VAO A;  5L6G A;  1W1M A;  2VFR A;  3SR6 B;  5HHZ A;  1N63 C;  3EJD B;  2W55 A;  3FW7 A;  3NVY B;  4O95 A;  5AE3 A;  2P13 A;  3DED A;  4MLA A;  3AN1 A;  1FFV C;  1I19 A;  1V97 A;  3TSJ A;  3NS1 B;  1W1J A;  4ZOH B;  1W1Q A;  4EC3 A;  2Q4W A;  1DII A;  1N5X A;  4BC7 A; 
#chains in the Genus database with same CATH homology
 3W8X A;  5AE1 A;  3EUB 3;  4PVJ A;  3NVW B;  3FWA A;  1HSK A;  2W3R A;  4UD8 A;  1E8H A;  1MBB A;  1AHU A;  1T3Q C;  2PLI A;  3JS8 A;  2R2Z A;  3LAE A;  2VFT A;  2P4P A;  1DIQ A;  1DZN A;  2BVF A;  1QLU A;  5I1W A;  1W1S A;  1ZR6 A;  3D2D A;  3C0P A;  3RJ8 A;  4ML8 A;  5ADZ A;  1N5W C;  3D2J A;  2GQU A;  1VAO A;  4DNS A;  2UUV A;  2EXR A;  3W8Z A;  2QPM A;  3PM9 A;  3NRZ B;  4PYT A;  1E8G A;  3RJA A;  5K8E A;  1RM6 B;  5FXP A;  1W1L A;  4PWC A;  2AXR A;  4PZF A;  1QLT A;  1FO4 A;  3FW8 A;  2VFV A;  2YVS A;  1AHV A;  3TX1 A;  1VDV A;  4BBY A;  2E3T A;  1F0X A;  4PVK A;  2P3H A;  1WVE A;  3AMZ A;  1FIQ B;  2BVG A;  1W1K A;  4HG0 A;  3HSU A;  1N60 C;  2W3S A;  2I0K A;  2UUU A;  1WYG A;  3FW9 A;  3DQ0 A;  2BVH A;  1WVF A;  1JRP A;  3BW7 A;  1E8F A;  5HQX A;  2IPI A;  2Y4G A;  1N62 C;  4PVE A;  5G5H B;  2WDW A;  3POP A;  4XLO A;  2Y08 A;  5FXF A;  3W8W A;  4BC9 A;  3AM9 A;  1SB3 B;  3ETR B;  3S1E A;  3S1F A;  3KJM A;  1W1O A;  5AE2 A;  2Y3R A;  2Q85 A;  3NVZ B;  3S1C A;  1UXY A;  3I99 A;  1E0Y A;  4JAY A;  4OAL A;  5D79 A;  2W54 A;  1W1R A;  2RK5 A;  1AHZ A;  2QKN A;  3LLB A;  3TSH A;  5HMR A;  3PQB A;  5AWV A;  3GSY A;  4PVH A;  2NQW A;  1FFU C;  4JB1 A;  2Y3S A;  2VFU A;  3S1D A;  1N61 C;  2R8D A;  4BCA A;  3HRD C;  3VTE A;  2OAI A;  1MBT A;  1JRO A;  2MBR A;  2PLS A;  5FXE A;  5L6F A;  3NVV B;  5I1V A;  3B9J B;  4PWB A;  2GQT A;  2O3G A;  3D2H A;  5FXD A;  1ZXI C;  5G5G B;  2VFS A;  2VAO A;  5L6G A;  1W1M A;  2VFR A;  3SR6 B;  5HHZ A;  1N63 C;  2W55 A;  3FW7 A;  3NVY B;  4O95 A;  5AE3 A;  2P13 A;  3DED A;  4MLA A;  3AN1 A;  1FFV C;  1I19 A;  1V97 A;  3TSJ A;  3NS1 B;  1W1J A;  4ZOH B;  1W1Q A;  4EC3 A;  2Q4W A;  1DII A;  1N5X A;  4BC7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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