4PZFA

Berberine bridge enzyme g164a variant, a reticuline dehydrogenase
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
498
structure length
498
Chain Sequence
DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAAWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Reticuline oxidase
publication title Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.
pubmed doi rcsb
source organism Eschscholzia californica
molecule tags Oxidoreductase
total genus 163
structure length 498
sequence length 498
chains with identical sequence B, C, D
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2014-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4pzfA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4pzfA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4pzfA03
3GSYA 2BVFA 1N63C 3D2DA 3HSUA 3NRZB 1DIQA 3ETRB 1FO4A 4EC3A 3TX1A 2VFTA 1HSKA 2Q4WA 1W1OA 4PVKA 5AWVA 2BVGA 2E3TA 1MBBA 4OALA 4BC9A 2AXRA 1T3QC 2GQTA 3D2HA 3SR6B 2QKNA 3C0PA 4PWCA 2WDWA 4PVHA 2VFUA 3BW7A 1MBTA 1N5XA 3AN1A 5HMRA 4UD8A 2Y4GA 3W8WA 5D79A 1W1JA 1ZR6A 3S1FA 3S1EA 4BBYA 5FXPA 4MLAA 1QLUA 3POPA 1FIQB 3FWAA 1E8GA 2QPMA 2I0KA 5K8EA 4PYTA 2Y3SA 5L6FA 3NS1B 1AHVA 3PQBA 1F0XA 5AE3A 2BVHA 5FXEA 1AHUA 1FFUC 1FFVC 4DNSA 1W1LA 4JB1A 1E8HA 3KJMA 1W1RA 2W3RA 1AHZA 3AM9A 3B9JB 3DQ0A 4BCAA 5AE1A 1JROA 1ZXIC 4ML8A 3FW7A 1W1MA 3S1CA 2Y3RA 4O95A 5I1WA 2Y08A 1E8FA 3I99A 1UXYA 3FW9A 4PZFA 1WVFA 1N60C 3TSHA 5ADZA 4XLOA 3VTEA 4JAYA 3EUB3 4PWBA 2VFVA 2IPIA 1I19A 2W54A 1E0YA 1WVEA 4ZOHB 5HHZA 5HQXA 3TSJA 1W1KA 2VAOA 5FXDA 1N5WC 1W1SA 2EXRA 3JS8A 2W3SA 2VFSA 3W8ZA 2VFRA 4PVJA 1VDVA 3NVZB 1V97A 3RJAA 1N62C 2GQUA 1WYGA 1N61C 3D2JA 1W1QA 3FW8A 3RJ8A 3W8XA 2W55A 4BC7A 5FXFA 5L6GA 5AE2A 5I1VA 2Q85A 4PVEA 3AMZA 3PM9A 1DIIA 3S1DA 1DZNA 1QLTA 1VAOA 2MBRA
chains in the Genus database with same CATH superfamily
3GSYA 2BVFA 1N63C 3D2DA 3HSUA 3NRZB 1DIQA 3ETRB 2P3HA 1FO4A 4EC3A 3TX1A 2VFTA 1HSKA 2Q4WA 2UUUA 4HG0A 1W1OA 4PVKA 5AWVA 2RK5A 2BVGA 2E3TA 1MBBA 4OALA 4BC9A 2AXRA 1T3QC 2GQTA 3D2HA 3SR6B 2QKNA 3C0PA 4PWCA 2WDWA 4PVHA 2VFUA 3BW7A 1MBTA 1N5XA 3AN1A 5HMRA 4UD8A 3DEDA 2Y4GA 3W8WA 3LAEA 5D79A 1W1JA 1ZR6A 3S1FA 3EJDB 3S1EA 3NVYB 4BBYA 5FXPA 3NVWB 4MLAA 1QLUA 3POPA 1FIQB 3NVVB 3FWAA 1E8GA 2QPMA 2I0KA 5K8EA 4PYTA 2Y3SA 2OAIA 5L6FA 3NS1B 1AHVA 2O3GA 1F0XA 5AE3A 3PQBA 2BVHA 5FXEA 1AHUA 1FFUC 1FFVC 4DNSA 1W1LA 3EJEB 4JB1A 1E8HA 2YVSA 3KJMA 2R2ZA 5G5GB 1W1RA 2W3RA 1AHZA 3AM9A 3B9JB 3DQ0A 4BCAA 5AE1A 2P13A 1JROA 1ZXIC 4ML8A 3FW7A 1W1MA 3S1CA 2PLIA 2Y3RA 4O95A 5I1WA 2Y08A 1E8FA 3I99A 1UXYA 3FW9A 4PZFA 1WVFA 1N60C 3TSHA 5ADZA 4XLOA 3VTEA 4JAYA 3EUB3 4PWBA 2VFVA 2IPIA 1I19A 2W54A 1E0YA 1WVEA 4ZOHB 5HHZA 5HQXA 3TSJA 1W1KA 2VAOA 5FXDA 1JRPA 3HRDC 1N5WC 1W1SA 2EXRA 3JS8A 2W3SA 2VFSA 3W8ZA 2VFRA 3EJBB 4PVJA 2P4PA 2NQWA 1VDVA 3NVZB 1V97A 5G5HB 3RJAA 1N62C 2GQUA 1WYGA 1N61C 3D2JA 2PLSA 1W1QA 1SB3B 3FW8A 3RJ8A 3W8XA 2W55A 4BC7A 5FXFA 5L6GA 2R8DA 2UUVA 5AE2A 5I1VA 2Q85A 4PVEA 3AMZA 3PM9A 1DIIA 3S1DA 1DZNA 1RM6B 1QLTA 3LLBA 1VAOA 2MBRA
chains in the Genus database with same CATH topology
3GSYA 2BVFA 1N63C 3D2DA 3HSUA 3NRZB 1DIQA 3ETRB 2P3HA 1FO4A 4EC3A 3TX1A 2VFTA 1HSKA 2Q4WA 2UUUA 4HG0A 1W1OA 4PVKA 5AWVA 2RK5A 2BVGA 2E3TA 1MBBA 4OALA 4BC9A 2AXRA 1T3QC 2GQTA 3D2HA 3SR6B 2QKNA 3C0PA 4PWCA 2WDWA 4PVHA 2VFUA 3BW7A 1MBTA 1N5XA 3AN1A 5HMRA 4UD8A 3DEDA 2Y4GA 3W8WA 3LAEA 5D79A 1W1JA 1ZR6A 3S1FA 3S1EA 4BBYA 3NVYB 5FXPA 4MLAA 3NVWB 1QLUA 3POPA 1FIQB 3NVVB 3FWAA 1E8GA 2QPMA 2I0KA 5K8EA 4PYTA 2Y3SA 2OAIA 5L6FA 3NS1B 1AHVA 2O3GA 1F0XA 5AE3A 3PQBA 2BVHA 5FXEA 1AHUA 1FFUC 1FFVC 4DNSA 1W1LA 4JB1A 1E8HA 2YVSA 3KJMA 2R2ZA 5G5GB 1W1RA 2W3RA 1AHZA 3AM9A 3B9JB 3DQ0A 4BCAA 5AE1A 2P13A 1JROA 1ZXIC 4ML8A 3FW7A 1W1MA 3S1CA 2PLIA 2Y3RA 4O95A 5I1WA 2Y08A 1E8FA 3I99A 1UXYA 3FW9A 4PZFA 1WVFA 1N60C 3TSHA 5ADZA 4XLOA 3VTEA 4JAYA 3EUB3 4PWBA 2VFVA 2IPIA 1I19A 2W54A 1E0YA 1WVEA 4ZOHB 5HHZA 5HQXA 3TSJA 1W1KA 2VAOA 5FXDA 1JRPA 3HRDC 1N5WC 1W1SA 2EXRA 3JS8A 2W3SA 2VFSA 3W8ZA 2VFRA 4PVJA 2P4PA 2NQWA 1VDVA 3NVZB 1V97A 5G5HB 3RJAA 1N62C 2GQUA 1WYGA 1N61C 3D2JA 2PLSA 1W1QA 1SB3B 3FW8A 3RJ8A 3W8XA 2W55A 4BC7A 5FXFA 5L6GA 2R8DA 2UUVA 5AE2A 5I1VA 2Q85A 4PVEA 3AMZA 3PM9A 1DIIA 3S1DA 1DZNA 1RM6B 1QLTA 3LLBA 1VAOA 2MBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GSY A;  2BVF A;  1N63 C;  3D2D A;  3HSU A;  3NRZ B;  1DIQ A;  3ETR B;  1FO4 A;  4EC3 A;  3TX1 A;  2VFT A;  1HSK A;  2Q4W A;  1W1O A;  4PVK A;  5AWV A;  2BVG A;  2E3T A;  1MBB A;  4OAL A;  4BC9 A;  2AXR A;  1T3Q C;  2GQT A;  3D2H A;  3SR6 B;  2QKN A;  3C0P A;  4PWC A;  2WDW A;  4PVH A;  2VFU A;  3BW7 A;  1MBT A;  1N5X A;  3AN1 A;  5HMR A;  4UD8 A;  2Y4G A;  3W8W A;  5D79 A;  1W1J A;  1ZR6 A;  3S1F A;  3S1E A;  4BBY A;  5FXP A;  4MLA A;  1QLU A;  3POP A;  1FIQ B;  3FWA A;  1E8G A;  2QPM A;  2I0K A;  5K8E A;  4PYT A;  2Y3S A;  5L6F A;  3NS1 B;  1AHV A;  3PQB A;  1F0X A;  5AE3 A;  2BVH A;  5FXE A;  1AHU A;  1FFU C;  1FFV C;  4DNS A;  1W1L A;  4JB1 A;  1E8H A;  3KJM A;  1W1R A;  2W3R A;  1AHZ A;  3AM9 A;  3B9J B;  3DQ0 A;  4BCA A;  5AE1 A;  1JRO A;  1ZXI C;  4ML8 A;  3FW7 A;  1W1M A;  3S1C A;  2Y3R A;  4O95 A;  5I1W A;  2Y08 A;  1E8F A;  3I99 A;  1UXY A;  3FW9 A;  4PZF A;  1WVF A;  1N60 C;  3TSH A;  5ADZ A;  4XLO A;  3VTE A;  4JAY A;  3EUB 3;  4PWB A;  2VFV A;  2IPI A;  1I19 A;  2W54 A;  1E0Y A;  1WVE A;  4ZOH B;  5HHZ A;  5HQX A;  3TSJ A;  1W1K A;  2VAO A;  5FXD A;  1N5W C;  1W1S A;  2EXR A;  3JS8 A;  2W3S A;  2VFS A;  3W8Z A;  2VFR A;  4PVJ A;  1VDV A;  3NVZ B;  1V97 A;  3RJA A;  1N62 C;  2GQU A;  1WYG A;  1N61 C;  3D2J A;  1W1Q A;  3FW8 A;  3RJ8 A;  3W8X A;  2W55 A;  4BC7 A;  5FXF A;  5L6G A;  5AE2 A;  5I1V A;  2Q85 A;  4PVE A;  3AMZ A;  3PM9 A;  1DII A;  3S1D A;  1DZN A;  1QLT A;  1VAO A;  2MBR A; 
#chains in the Genus database with same CATH topology
 3GSY A;  2BVF A;  1N63 C;  3D2D A;  3HSU A;  3NRZ B;  1DIQ A;  3ETR B;  2P3H A;  1FO4 A;  4EC3 A;  3TX1 A;  2VFT A;  1HSK A;  2Q4W A;  2UUU A;  4HG0 A;  1W1O A;  4PVK A;  5AWV A;  2RK5 A;  2BVG A;  2E3T A;  1MBB A;  4OAL A;  4BC9 A;  2AXR A;  1T3Q C;  2GQT A;  3D2H A;  3SR6 B;  2QKN A;  3C0P A;  4PWC A;  2WDW A;  4PVH A;  2VFU A;  3BW7 A;  1MBT A;  1N5X A;  3AN1 A;  5HMR A;  4UD8 A;  3DED A;  2Y4G A;  3W8W A;  3LAE A;  5D79 A;  1W1J A;  1ZR6 A;  3S1F A;  3EJD B;  3S1E A;  3NVY B;  4BBY A;  5FXP A;  3NVW B;  4MLA A;  1QLU A;  3POP A;  1FIQ B;  3NVV B;  3FWA A;  1E8G A;  2QPM A;  2I0K A;  5K8E A;  4PYT A;  2Y3S A;  2OAI A;  5L6F A;  3NS1 B;  1AHV A;  2O3G A;  1F0X A;  5AE3 A;  3PQB A;  2BVH A;  5FXE A;  1AHU A;  1FFU C;  1FFV C;  4DNS A;  1W1L A;  3EJE B;  4JB1 A;  1E8H A;  2YVS A;  3KJM A;  2R2Z A;  5G5G B;  1W1R A;  2W3R A;  1AHZ A;  3AM9 A;  3B9J B;  3DQ0 A;  4BCA A;  5AE1 A;  2P13 A;  1JRO A;  1ZXI C;  4ML8 A;  3FW7 A;  1W1M A;  3S1C A;  2PLI A;  2Y3R A;  4O95 A;  5I1W A;  2Y08 A;  1E8F A;  3I99 A;  1UXY A;  3FW9 A;  4PZF A;  1WVF A;  1N60 C;  3TSH A;  5ADZ A;  4XLO A;  3VTE A;  4JAY A;  3EUB 3;  4PWB A;  2VFV A;  2IPI A;  1I19 A;  2W54 A;  1E0Y A;  1WVE A;  4ZOH B;  5HHZ A;  5HQX A;  3TSJ A;  1W1K A;  2VAO A;  5FXD A;  1JRP A;  3HRD C;  1N5W C;  1W1S A;  2EXR A;  3JS8 A;  2W3S A;  2VFS A;  3W8Z A;  2VFR A;  3EJB B;  4PVJ A;  2P4P A;  2NQW A;  1VDV A;  3NVZ B;  1V97 A;  5G5H B;  3RJA A;  1N62 C;  2GQU A;  1WYG A;  1N61 C;  3D2J A;  2PLS A;  1W1Q A;  1SB3 B;  3FW8 A;  3RJ8 A;  3W8X A;  2W55 A;  4BC7 A;  5FXF A;  5L6G A;  2R8D A;  2UUV A;  5AE2 A;  5I1V A;  2Q85 A;  4PVE A;  3AMZ A;  3PM9 A;  1DII A;  3S1D A;  1DZN A;  1RM6 B;  1QLT A;  3LLB A;  1VAO A;  2MBR A; 
#chains in the Genus database with same CATH homology
 3GSY A;  2BVF A;  1N63 C;  3D2D A;  3HSU A;  3NRZ B;  1DIQ A;  3ETR B;  2P3H A;  1FO4 A;  4EC3 A;  3TX1 A;  2VFT A;  1HSK A;  2Q4W A;  2UUU A;  4HG0 A;  1W1O A;  4PVK A;  5AWV A;  2RK5 A;  2BVG A;  2E3T A;  1MBB A;  4OAL A;  4BC9 A;  2AXR A;  1T3Q C;  2GQT A;  3D2H A;  3SR6 B;  2QKN A;  3C0P A;  4PWC A;  2WDW A;  4PVH A;  2VFU A;  3BW7 A;  1MBT A;  1N5X A;  3AN1 A;  5HMR A;  4UD8 A;  3DED A;  2Y4G A;  3W8W A;  3LAE A;  5D79 A;  1W1J A;  1ZR6 A;  3S1F A;  3S1E A;  4BBY A;  3NVY B;  5FXP A;  4MLA A;  3NVW B;  1QLU A;  3POP A;  1FIQ B;  3NVV B;  3FWA A;  1E8G A;  2QPM A;  2I0K A;  5K8E A;  4PYT A;  2Y3S A;  2OAI A;  5L6F A;  3NS1 B;  1AHV A;  2O3G A;  1F0X A;  5AE3 A;  3PQB A;  2BVH A;  5FXE A;  1AHU A;  1FFU C;  1FFV C;  4DNS A;  1W1L A;  4JB1 A;  1E8H A;  2YVS A;  3KJM A;  2R2Z A;  5G5G B;  1W1R A;  2W3R A;  1AHZ A;  3AM9 A;  3B9J B;  3DQ0 A;  4BCA A;  5AE1 A;  2P13 A;  1JRO A;  1ZXI C;  4ML8 A;  3FW7 A;  1W1M A;  3S1C A;  2PLI A;  2Y3R A;  4O95 A;  5I1W A;  2Y08 A;  1E8F A;  3I99 A;  1UXY A;  3FW9 A;  4PZF A;  1WVF A;  1N60 C;  3TSH A;  5ADZ A;  4XLO A;  3VTE A;  4JAY A;  3EUB 3;  4PWB A;  2VFV A;  2IPI A;  1I19 A;  2W54 A;  1E0Y A;  1WVE A;  4ZOH B;  5HHZ A;  5HQX A;  3TSJ A;  1W1K A;  2VAO A;  5FXD A;  1JRP A;  3HRD C;  1N5W C;  1W1S A;  2EXR A;  3JS8 A;  2W3S A;  2VFS A;  3W8Z A;  2VFR A;  4PVJ A;  2P4P A;  2NQW A;  1VDV A;  3NVZ B;  1V97 A;  5G5H B;  3RJA A;  1N62 C;  2GQU A;  1WYG A;  1N61 C;  3D2J A;  2PLS A;  1W1Q A;  1SB3 B;  3FW8 A;  3RJ8 A;  3W8X A;  2W55 A;  4BC7 A;  5FXF A;  5L6G A;  2R8D A;  2UUV A;  5AE2 A;  5I1V A;  2Q85 A;  4PVE A;  3AMZ A;  3PM9 A;  1DII A;  3S1D A;  1DZN A;  1RM6 B;  1QLT A;  3LLB A;  1VAO A;  2MBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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