4PZFA

Berberine bridge enzyme g164a variant, a reticuline dehydrogenase
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
498
structure length
498
Chain Sequence
DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAAWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.
pubmed doi rcsb
source organism Eschscholzia californica
molecule tags Oxidoreductase
molecule keywords Reticuline oxidase
total genus 163
structure length 498
sequence length 498
chains with identical sequence B, C, D
ec nomenclature ec 1.21.3.3: Reticuline oxidase.
pdb deposition date 2014-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4pzfA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4pzfA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4pzfA03
5FXEA 3W8XA 3W8ZA 2VFSA 1N62C 3HSUA 1T3QC 1VDVA 5AE1A 1FFVC 2EXRA 2W3SA 3AMZA 3W8WA 3RJAA 3NRZB 3S1FA 4O95A 5L6GA 5FXPA 1AHVA 5L6FA 1MBBA 1WVFA 5I1VA 3NVZB 1HSKA 1DIIA 2Q85A 3VTEA 5D79A 3TSHA 1JROA 4BBYA 3S1CA 1E8GA 2W54A 3BW7A 3D2JA 4OALA 1AHUA 5FXDA 4XLOA 2Y3RA 1V97A 1VAOA 3FWAA 2AXRA 4EC3A 3GSYA 1MBTA 5HHZA 4PVHA 3AN1A 1QLUA 1UXYA 4PVEA 1DZNA 2QPMA 5FXFA 1I19A 3TX1A 3B9JB 3S1EA 2Y08A 2WDWA 3EUB3 4BC9A 1FFUC 1N5XA 3S1DA 2VFRA 4JB1A 2MBRA 1WYGA 3FW7A 1WVEA 4ML8A 4PWBA 2Y3SA 2IPIA 1N60C 2E3TA 1E0YA 3I99A 3KJMA 1F0XA 4ZOHB 1AHZA 3NS1B 3ETRB 2BVGA 5ADZA 2W55A 3D2DA 1FO4A 2VAOA 5I1WA 4BC7A 1E8HA 2BVHA 1N61C 1W1RA 4PZFA 2GQUA 3JS8A 4PWCA 3D2HA 1W1QA 2VFTA 2I0KA 3FW8A 2Q4WA 1DIQA 5HMRA 4PYTA 2BVFA 2Y4GA 5K8EA 1ZR6A 2W3RA 4UD8A 3RJ8A 1N5WC 3AM9A 4PVKA 4DNSA 1W1JA 1ZXIC 4BCAA 4PVJA 1W1LA 5HQXA 1N63C 3FW9A 4MLAA 5AE2A 3PQBA 5AWVA 1QLTA 3DQ0A 3PM9A 3SR6B 1W1OA 2GQTA 3TSJA 1W1SA 3POPA 3C0PA 5AE3A 1E8FA 1W1MA 1W1KA 2QKNA 2VFVA 4JAYA 1FIQB 2VFUA
chains in the Genus database with same CATH superfamily
5FXEA 3W8XA 3W8ZA 2YVSA 2VFSA 1N62C 3HSUA 1T3QC 1VDVA 5AE1A 3NVYB 1FFVC 2EXRA 2W3SA 3AMZA 3W8WA 1SB3B 3RJAA 3NRZB 3S1FA 4O95A 5L6GA 5FXPA 2P4PA 2P13A 3NVVB 1AHVA 4HG0A 5G5HB 5L6FA 2NQWA 1MBBA 1WVFA 5I1VA 3NVZB 1HSKA 1DIIA 2Q85A 3VTEA 5D79A 3TSHA 1JROA 4BBYA 3S1CA 1E8GA 2W54A 3BW7A 3D2JA 4OALA 1AHUA 5FXDA 4XLOA 2Y3RA 1V97A 1VAOA 3FWAA 2AXRA 4EC3A 3GSYA 1MBTA 5HHZA 4PVHA 3AN1A 2RK5A 3LAEA 1QLUA 1UXYA 4PVEA 1DZNA 2QPMA 5FXFA 2O3GA 2UUVA 2UUUA 1I19A 3TX1A 3B9JB 2R8DA 3S1EA 2Y08A 3DEDA 2WDWA 3EUB3 4BC9A 1FFUC 1N5XA 3S1DA 2VFRA 4JB1A 2MBRA 1WYGA 3FW7A 1WVEA 4ML8A 4PWBA 2Y3SA 2IPIA 1N60C 2E3TA 1E0YA 3I99A 3KJMA 1RM6B 1F0XA 4ZOHB 1AHZA 3NS1B 3HRDC 3ETRB 2BVGA 5ADZA 2W55A 2R2ZA 3D2DA 1FO4A 2VAOA 5I1WA 3EJEB 4BC7A 1E8HA 2OAIA 2BVHA 1N61C 1W1RA 3EJBB 4PZFA 2GQUA 3JS8A 4PWCA 3D2HA 1W1QA 2VFTA 2I0KA 3FW8A 2Q4WA 1DIQA 5HMRA 2PLIA 4PYTA 2BVFA 2Y4GA 5K8EA 1JRPA 1ZR6A 2W3RA 4UD8A 3LLBA 1N5WC 3EJDB 3RJ8A 3AM9A 4PVKA 2PLSA 4DNSA 1W1JA 1ZXIC 2P3HA 4BCAA 4PVJA 5G5GB 1W1LA 5HQXA 1N63C 3FW9A 4MLAA 5AE2A 3PQBA 5AWVA 1QLTA 3DQ0A 3PM9A 3SR6B 1W1OA 2GQTA 3TSJA 1W1SA 3POPA 3C0PA 5AE3A 1E8FA 1W1MA 1W1KA 2QKNA 2VFVA 3NVWB 4JAYA 1FIQB 2VFUA
chains in the Genus database with same CATH topology
5FXEA 3W8XA 3W8ZA 2YVSA 2VFSA 1N62C 3HSUA 1T3QC 1VDVA 5AE1A 3NVYB 1FFVC 2EXRA 2W3SA 3AMZA 3W8WA 1SB3B 3RJAA 3NRZB 3S1FA 4O95A 5L6GA 5FXPA 2P4PA 2P13A 3NVVB 1AHVA 4HG0A 5G5HB 5L6FA 2NQWA 1MBBA 1WVFA 5I1VA 3NVZB 1HSKA 1DIIA 2Q85A 3VTEA 5D79A 3TSHA 1JROA 4BBYA 3S1CA 1E8GA 2W54A 3BW7A 3D2JA 4OALA 1AHUA 5FXDA 4XLOA 2Y3RA 1V97A 1VAOA 3FWAA 2AXRA 4EC3A 3GSYA 1MBTA 5HHZA 4PVHA 3AN1A 2RK5A 3LAEA 1QLUA 1UXYA 4PVEA 1DZNA 2QPMA 5FXFA 2O3GA 2UUVA 2UUUA 1I19A 3TX1A 3B9JB 2R8DA 3S1EA 2Y08A 3DEDA 2WDWA 3EUB3 4BC9A 1FFUC 1N5XA 3S1DA 2VFRA 4JB1A 2MBRA 1WYGA 3FW7A 1WVEA 4ML8A 4PWBA 2Y3SA 2IPIA 1N60C 2E3TA 1E0YA 3I99A 3KJMA 1RM6B 1F0XA 4ZOHB 1AHZA 3NS1B 3HRDC 3ETRB 2BVGA 5ADZA 2W55A 2R2ZA 3D2DA 1FO4A 2VAOA 5I1WA 4BC7A 1E8HA 2OAIA 2BVHA 1N61C 1W1RA 4PZFA 2GQUA 3JS8A 4PWCA 3D2HA 1W1QA 2VFTA 2I0KA 3FW8A 2Q4WA 1DIQA 5HMRA 2PLIA 4PYTA 2BVFA 2Y4GA 5K8EA 1JRPA 1ZR6A 2W3RA 4UD8A 3LLBA 1N5WC 3RJ8A 3AM9A 4PVKA 2PLSA 4DNSA 1W1JA 1ZXIC 2P3HA 4BCAA 4PVJA 5G5GB 1W1LA 5HQXA 1N63C 3FW9A 4MLAA 5AE2A 3PQBA 5AWVA 1QLTA 3DQ0A 3PM9A 3SR6B 1W1OA 2GQTA 3TSJA 1W1SA 3POPA 3C0PA 5AE3A 1E8FA 1W1MA 1W1KA 2QKNA 2VFVA 3NVWB 4JAYA 1FIQB 2VFUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FXE A;  3W8X A;  3W8Z A;  2VFS A;  1N62 C;  3HSU A;  1T3Q C;  1VDV A;  5AE1 A;  1FFV C;  2EXR A;  2W3S A;  3AMZ A;  3W8W A;  3RJA A;  3NRZ B;  3S1F A;  4O95 A;  5L6G A;  5FXP A;  1AHV A;  5L6F A;  1MBB A;  1WVF A;  5I1V A;  3NVZ B;  1HSK A;  1DII A;  2Q85 A;  3VTE A;  5D79 A;  3TSH A;  1JRO A;  4BBY A;  3S1C A;  1E8G A;  2W54 A;  3BW7 A;  3D2J A;  4OAL A;  1AHU A;  5FXD A;  4XLO A;  2Y3R A;  1V97 A;  1VAO A;  3FWA A;  2AXR A;  4EC3 A;  3GSY A;  1MBT A;  5HHZ A;  4PVH A;  3AN1 A;  1QLU A;  1UXY A;  4PVE A;  1DZN A;  2QPM A;  5FXF A;  1I19 A;  3TX1 A;  3B9J B;  3S1E A;  2Y08 A;  2WDW A;  3EUB 3;  4BC9 A;  1FFU C;  1N5X A;  3S1D A;  2VFR A;  4JB1 A;  2MBR A;  1WYG A;  3FW7 A;  1WVE A;  4ML8 A;  4PWB A;  2Y3S A;  2IPI A;  1N60 C;  2E3T A;  1E0Y A;  3I99 A;  3KJM A;  1F0X A;  4ZOH B;  1AHZ A;  3NS1 B;  3ETR B;  2BVG A;  5ADZ A;  2W55 A;  3D2D A;  1FO4 A;  2VAO A;  5I1W A;  4BC7 A;  1E8H A;  2BVH A;  1N61 C;  1W1R A;  4PZF A;  2GQU A;  3JS8 A;  4PWC A;  3D2H A;  1W1Q A;  2VFT A;  2I0K A;  3FW8 A;  2Q4W A;  1DIQ A;  5HMR A;  4PYT A;  2BVF A;  2Y4G A;  5K8E A;  1ZR6 A;  2W3R A;  4UD8 A;  3RJ8 A;  1N5W C;  3AM9 A;  4PVK A;  4DNS A;  1W1J A;  1ZXI C;  4BCA A;  4PVJ A;  1W1L A;  5HQX A;  1N63 C;  3FW9 A;  4MLA A;  5AE2 A;  3PQB A;  5AWV A;  1QLT A;  3DQ0 A;  3PM9 A;  3SR6 B;  1W1O A;  2GQT A;  3TSJ A;  1W1S A;  3POP A;  3C0P A;  5AE3 A;  1E8F A;  1W1M A;  1W1K A;  2QKN A;  2VFV A;  4JAY A;  1FIQ B;  2VFU A; 
#chains in the Genus database with same CATH topology
 5FXE A;  3W8X A;  3W8Z A;  2YVS A;  2VFS A;  1N62 C;  3HSU A;  1T3Q C;  1VDV A;  5AE1 A;  3NVY B;  1FFV C;  2EXR A;  2W3S A;  3AMZ A;  3W8W A;  1SB3 B;  3RJA A;  3NRZ B;  3S1F A;  4O95 A;  5L6G A;  5FXP A;  2P4P A;  2P13 A;  3NVV B;  1AHV A;  4HG0 A;  5G5H B;  5L6F A;  2NQW A;  1MBB A;  1WVF A;  5I1V A;  3NVZ B;  1HSK A;  1DII A;  2Q85 A;  3VTE A;  5D79 A;  3TSH A;  1JRO A;  4BBY A;  3S1C A;  1E8G A;  2W54 A;  3BW7 A;  3D2J A;  4OAL A;  1AHU A;  5FXD A;  4XLO A;  2Y3R A;  1V97 A;  1VAO A;  3FWA A;  2AXR A;  4EC3 A;  3GSY A;  1MBT A;  5HHZ A;  4PVH A;  3AN1 A;  2RK5 A;  3LAE A;  1QLU A;  1UXY A;  4PVE A;  1DZN A;  2QPM A;  5FXF A;  2O3G A;  2UUV A;  2UUU A;  1I19 A;  3TX1 A;  3B9J B;  2R8D A;  3S1E A;  2Y08 A;  3DED A;  2WDW A;  3EUB 3;  4BC9 A;  1FFU C;  1N5X A;  3S1D A;  2VFR A;  4JB1 A;  2MBR A;  1WYG A;  3FW7 A;  1WVE A;  4ML8 A;  4PWB A;  2Y3S A;  2IPI A;  1N60 C;  2E3T A;  1E0Y A;  3I99 A;  3KJM A;  1RM6 B;  1F0X A;  4ZOH B;  1AHZ A;  3NS1 B;  3HRD C;  3ETR B;  2BVG A;  5ADZ A;  2W55 A;  2R2Z A;  3D2D A;  1FO4 A;  2VAO A;  5I1W A;  3EJE B;  4BC7 A;  1E8H A;  2OAI A;  2BVH A;  1N61 C;  1W1R A;  3EJB B;  4PZF A;  2GQU A;  3JS8 A;  4PWC A;  3D2H A;  1W1Q A;  2VFT A;  2I0K A;  3FW8 A;  2Q4W A;  1DIQ A;  5HMR A;  2PLI A;  4PYT A;  2BVF A;  2Y4G A;  5K8E A;  1JRP A;  1ZR6 A;  2W3R A;  4UD8 A;  3LLB A;  1N5W C;  3EJD B;  3RJ8 A;  3AM9 A;  4PVK A;  2PLS A;  4DNS A;  1W1J A;  1ZXI C;  2P3H A;  4BCA A;  4PVJ A;  5G5G B;  1W1L A;  5HQX A;  1N63 C;  3FW9 A;  4MLA A;  5AE2 A;  3PQB A;  5AWV A;  1QLT A;  3DQ0 A;  3PM9 A;  3SR6 B;  1W1O A;  2GQT A;  3TSJ A;  1W1S A;  3POP A;  3C0P A;  5AE3 A;  1E8F A;  1W1M A;  1W1K A;  2QKN A;  2VFV A;  3NVW B;  4JAY A;  1FIQ B;  2VFU A; 
#chains in the Genus database with same CATH homology
 5FXE A;  3W8X A;  3W8Z A;  2YVS A;  2VFS A;  1N62 C;  3HSU A;  1T3Q C;  1VDV A;  5AE1 A;  3NVY B;  1FFV C;  2EXR A;  2W3S A;  3AMZ A;  3W8W A;  1SB3 B;  3RJA A;  3NRZ B;  3S1F A;  4O95 A;  5L6G A;  5FXP A;  2P4P A;  2P13 A;  3NVV B;  1AHV A;  4HG0 A;  5G5H B;  5L6F A;  2NQW A;  1MBB A;  1WVF A;  5I1V A;  3NVZ B;  1HSK A;  1DII A;  2Q85 A;  3VTE A;  5D79 A;  3TSH A;  1JRO A;  4BBY A;  3S1C A;  1E8G A;  2W54 A;  3BW7 A;  3D2J A;  4OAL A;  1AHU A;  5FXD A;  4XLO A;  2Y3R A;  1V97 A;  1VAO A;  3FWA A;  2AXR A;  4EC3 A;  3GSY A;  1MBT A;  5HHZ A;  4PVH A;  3AN1 A;  2RK5 A;  3LAE A;  1QLU A;  1UXY A;  4PVE A;  1DZN A;  2QPM A;  5FXF A;  2O3G A;  2UUV A;  2UUU A;  1I19 A;  3TX1 A;  3B9J B;  2R8D A;  3S1E A;  2Y08 A;  3DED A;  2WDW A;  3EUB 3;  4BC9 A;  1FFU C;  1N5X A;  3S1D A;  2VFR A;  4JB1 A;  2MBR A;  1WYG A;  3FW7 A;  1WVE A;  4ML8 A;  4PWB A;  2Y3S A;  2IPI A;  1N60 C;  2E3T A;  1E0Y A;  3I99 A;  3KJM A;  1RM6 B;  1F0X A;  4ZOH B;  1AHZ A;  3NS1 B;  3HRD C;  3ETR B;  2BVG A;  5ADZ A;  2W55 A;  2R2Z A;  3D2D A;  1FO4 A;  2VAO A;  5I1W A;  4BC7 A;  1E8H A;  2OAI A;  2BVH A;  1N61 C;  1W1R A;  4PZF A;  2GQU A;  3JS8 A;  4PWC A;  3D2H A;  1W1Q A;  2VFT A;  2I0K A;  3FW8 A;  2Q4W A;  1DIQ A;  5HMR A;  2PLI A;  4PYT A;  2BVF A;  2Y4G A;  5K8E A;  1JRP A;  1ZR6 A;  2W3R A;  4UD8 A;  3LLB A;  1N5W C;  3RJ8 A;  3AM9 A;  4PVK A;  2PLS A;  4DNS A;  1W1J A;  1ZXI C;  2P3H A;  4BCA A;  4PVJ A;  5G5G B;  1W1L A;  5HQX A;  1N63 C;  3FW9 A;  4MLA A;  5AE2 A;  3PQB A;  5AWV A;  1QLT A;  3DQ0 A;  3PM9 A;  3SR6 B;  1W1O A;  2GQT A;  3TSJ A;  1W1S A;  3POP A;  3C0P A;  5AE3 A;  1E8F A;  1W1M A;  1W1K A;  2QKN A;  2VFV A;  3NVW B;  4JAY A;  1FIQ B;  2VFU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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