3VTEA

Crystal structure of tetrahydrocannabinolic acid synthase from cannabis sativa
Total Genus 159
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
518
structure length
502
Chain Sequence
ANPRENFLKCFSKHIPNPKLVYTQHDQLYMSILNSTIQNLRFISDTTPKPLVIVTPSNNSHIQATILCSKKVGLQIRTRSGGHDAEGMSYISQVPFVVVDLRNMHSIKIDVHSQTAWVEAGATLGEVYYWINEKNENLSFPGGYCPTVGVGGHFSGGGYGALMRNYGLAADNIIDAHLVNVDGKVLDRKSMGEDLFWAIRGGGGENFGIIAAWKIKLVAVPSKSTIFSVKKNMEIHGLVKLFNKWQNIAYKYDKDLVLMTHFITKNITTTVHGYFSSIFHGGVDSLVDLMNKSFPELGIKKTDCKEFSWIDTTIFYSGVVNFKKEILLDRSAGKKTAFSIKLDYVKKPIPETAMVKILEKLYEEDVGAGMYVLYPYGGIMEEISESAIPFPHRAGIMYELWYTASWEKQEDNEKHINWVRSVYNFTTPYVSQNPRLAYLNYRDLDLGKTNHASPNNYTQARIWGEKYFGKNFNRLVKVKTKVDPNNFFRNEQSIPPLPPHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords Tetrahydrocannabinolic acid synthase
publication title Structure and function of 1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa
pubmed doi rcsb
source organism Cannabis sativa
total genus 159
structure length 502
sequence length 518
ec nomenclature ec 1.21.3.7: Tetrahydrocannabinolic acid synthase.
pdb deposition date 2012-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3vteA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3vteA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3vteA03
5AE3A 4BC9A 5HMRA 1W1QA 1FO4A 1FFUC 1N63C 4PWCA 3W8ZA 2Y3SA 1AHVA 3S1CA 1AHZA 2BVHA 5I1VA 2QPMA 3JS8A 4BBYA 1HSKA 2EXRA 4PVKA 1N5WC 2Y08A 2VFTA 4DNSA 4JAYA 1VDVA 2VFSA 5I1WA 2BVFA 5K8EA 1W1KA 1MBBA 1QLUA 5FXEA 2QKNA 3BW7A 4PVEA 5L6GA 1F0XA 3I99A 3D2HA 2VFUA 1E8HA 3RJAA 2AXRA 4UD8A 5HQXA 5FXPA 5AE1A 3FW8A 4O95A 2MBRA 2I0KA 2W3SA 1E8GA 1V97A 2E3TA 1N62C 3NS1B 1WYGA 1E8FA 2GQTA 5AE2A 2IPIA 4JB1A 4EC3A 4OALA 4PVHA 1W1SA 3S1DA 1DIQA 2WDWA 4XLOA 1WVEA 1I19A 3PQBA 1W1LA 1W1MA 1FFVC 4PWBA 1VAOA 4PVJA 2W3RA 2Q4WA 4ML8A 3D2DA 4MLAA 3TSHA 1N61C 5HHZA 2VFVA 3W8WA 1DZNA 5FXFA 3AM9A 1T3QC 3TSJA 1ZXIC 2VFRA 5D79A 1MBTA 1FIQB 2GQUA 3C0PA 3W8XA 3EUB3 3KJMA 1UXYA 1JROA 2BVGA 1E0YA 1W1OA 3DQ0A 3FWAA 1QLTA 4BCAA 3VTEA 2W54A 3POPA 3NVZB 3FW9A 3SR6B 5L6FA 3PM9A 5ADZA 3AN1A 3FW7A 2VAOA 2Y4GA 5FXDA 3D2JA 1AHUA 2Q85A 3B9JB 3HSUA 1ZR6A 3RJ8A 5AWVA 3AMZA 3S1FA 2Y3RA 1WVFA 4BC7A 1DIIA 3TX1A 4PZFA 1W1JA 1N5XA 2W55A 3ETRB 3NRZB 1W1RA 4PYTA 3GSYA 3S1EA 4ZOHB 1N60C
chains in the Genus database with same CATH superfamily
5AE3A 4BC9A 5HMRA 5G5GB 1W1QA 1FO4A 1FFUC 1N63C 4PWCA 1RM6B 3W8ZA 2Y3SA 1AHVA 3S1CA 1AHZA 2OAIA 2BVHA 3EJDB 3EJBB 2UUUA 5I1VA 2QPMA 3JS8A 4BBYA 1HSKA 2EXRA 4PVKA 1N5WC 2Y08A 2VFTA 4DNSA 4JAYA 3NVWB 1VDVA 2VFSA 3LLBA 5I1WA 2BVFA 5K8EA 1W1KA 5G5HB 2O3GA 1MBBA 1QLUA 5FXEA 2QKNA 3BW7A 4PVEA 5L6GA 1F0XA 3I99A 3D2HA 3DEDA 2VFUA 1E8HA 2UUVA 3RJAA 2AXRA 4UD8A 5HQXA 5FXPA 5AE1A 3FW8A 4O95A 4HG0A 2MBRA 2I0KA 2W3SA 1E8GA 1V97A 2E3TA 1N62C 3NS1B 2P13A 1WYGA 1E8FA 2GQTA 5AE2A 2P3HA 1JRPA 2IPIA 4JB1A 4EC3A 4OALA 4PVHA 1W1SA 3S1DA 1DIQA 2R8DA 2WDWA 4XLOA 1WVEA 1I19A 3PQBA 1W1LA 1W1MA 1FFVC 4PWBA 1VAOA 4PVJA 2W3RA 2YVSA 2Q4WA 4ML8A 3D2DA 3NVVB 4MLAA 3TSHA 1N61C 5HHZA 2VFVA 3W8WA 1DZNA 5FXFA 3AM9A 1T3QC 3NVYB 3TSJA 2NQWA 1ZXIC 2VFRA 5D79A 1MBTA 2RK5A 1FIQB 2GQUA 3C0PA 3W8XA 1SB3B 3EUB3 3KJMA 1UXYA 1JROA 2BVGA 1E0YA 1W1OA 3DQ0A 3FWAA 1QLTA 4BCAA 3VTEA 2W54A 3POPA 3NVZB 3FW9A 3SR6B 5L6FA 3PM9A 3LAEA 5ADZA 2PLSA 3AN1A 3FW7A 2VAOA 2P4PA 2Y4GA 3HRDC 3EJEB 5FXDA 3D2JA 1AHUA 2Q85A 2PLIA 2R2ZA 3B9JB 3HSUA 1ZR6A 3RJ8A 5AWVA 3AMZA 3S1FA 2Y3RA 1WVFA 4BC7A 1DIIA 3TX1A 4PZFA 1W1JA 1N5XA 2W55A 3ETRB 3NRZB 1W1RA 4PYTA 3GSYA 3S1EA 4ZOHB 1N60C
chains in the Genus database with same CATH topology
5AE3A 4BC9A 5HMRA 5G5GB 1W1QA 1FO4A 1FFUC 1N63C 4PWCA 1RM6B 3W8ZA 2Y3SA 1AHVA 3S1CA 1AHZA 2OAIA 2BVHA 2UUUA 5I1VA 2QPMA 3JS8A 4BBYA 1HSKA 2EXRA 4PVKA 1N5WC 2Y08A 2VFTA 4DNSA 4JAYA 3NVWB 1VDVA 2VFSA 3LLBA 5I1WA 2BVFA 5K8EA 1W1KA 5G5HB 2O3GA 1MBBA 1QLUA 5FXEA 2QKNA 3BW7A 4PVEA 5L6GA 1F0XA 3I99A 3D2HA 3DEDA 2VFUA 1E8HA 2UUVA 3RJAA 2AXRA 4UD8A 5HQXA 5FXPA 5AE1A 3FW8A 4O95A 4HG0A 2MBRA 2I0KA 2W3SA 1E8GA 1V97A 2E3TA 1N62C 3NS1B 2P13A 1WYGA 1E8FA 2GQTA 5AE2A 2P3HA 1JRPA 2IPIA 4JB1A 4EC3A 4OALA 4PVHA 1W1SA 3S1DA 1DIQA 2R8DA 2WDWA 4XLOA 1WVEA 1I19A 3PQBA 1W1LA 1W1MA 1FFVC 4PWBA 1VAOA 4PVJA 2W3RA 2YVSA 2Q4WA 4ML8A 3D2DA 3NVVB 4MLAA 3TSHA 1N61C 5HHZA 2VFVA 3W8WA 1DZNA 5FXFA 3AM9A 1T3QC 3NVYB 3TSJA 2NQWA 1ZXIC 2VFRA 5D79A 1MBTA 2RK5A 1FIQB 2GQUA 3C0PA 3W8XA 1SB3B 3EUB3 3KJMA 1UXYA 1JROA 2BVGA 1E0YA 1W1OA 3DQ0A 3FWAA 1QLTA 4BCAA 3VTEA 2W54A 3POPA 3NVZB 3FW9A 3SR6B 5L6FA 3PM9A 3LAEA 5ADZA 2PLSA 3AN1A 3FW7A 2VAOA 2P4PA 2Y4GA 3HRDC 5FXDA 3D2JA 1AHUA 2Q85A 2PLIA 2R2ZA 3B9JB 3HSUA 1ZR6A 3RJ8A 5AWVA 3AMZA 3S1FA 2Y3RA 1WVFA 4BC7A 1DIIA 3TX1A 4PZFA 1W1JA 1N5XA 2W55A 3ETRB 3NRZB 1W1RA 4PYTA 3GSYA 3S1EA 4ZOHB 1N60C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AE3 A;  4BC9 A;  5HMR A;  1W1Q A;  1FO4 A;  1FFU C;  1N63 C;  4PWC A;  3W8Z A;  2Y3S A;  1AHV A;  3S1C A;  1AHZ A;  2BVH A;  5I1V A;  2QPM A;  3JS8 A;  4BBY A;  1HSK A;  2EXR A;  4PVK A;  1N5W C;  2Y08 A;  2VFT A;  4DNS A;  4JAY A;  1VDV A;  2VFS A;  5I1W A;  2BVF A;  5K8E A;  1W1K A;  1MBB A;  1QLU A;  5FXE A;  2QKN A;  3BW7 A;  4PVE A;  5L6G A;  1F0X A;  3I99 A;  3D2H A;  2VFU A;  1E8H A;  3RJA A;  2AXR A;  4UD8 A;  5HQX A;  5FXP A;  5AE1 A;  3FW8 A;  4O95 A;  2MBR A;  2I0K A;  2W3S A;  1E8G A;  1V97 A;  2E3T A;  1N62 C;  3NS1 B;  1WYG A;  1E8F A;  2GQT A;  5AE2 A;  2IPI A;  4JB1 A;  4EC3 A;  4OAL A;  4PVH A;  1W1S A;  3S1D A;  1DIQ A;  2WDW A;  4XLO A;  1WVE A;  1I19 A;  3PQB A;  1W1L A;  1W1M A;  1FFV C;  4PWB A;  1VAO A;  4PVJ A;  2W3R A;  2Q4W A;  4ML8 A;  3D2D A;  4MLA A;  3TSH A;  1N61 C;  5HHZ A;  2VFV A;  3W8W A;  1DZN A;  5FXF A;  3AM9 A;  1T3Q C;  3TSJ A;  1ZXI C;  2VFR A;  5D79 A;  1MBT A;  1FIQ B;  2GQU A;  3C0P A;  3W8X A;  3EUB 3;  3KJM A;  1UXY A;  1JRO A;  2BVG A;  1E0Y A;  1W1O A;  3DQ0 A;  3FWA A;  1QLT A;  4BCA A;  3VTE A;  2W54 A;  3POP A;  3NVZ B;  3FW9 A;  3SR6 B;  5L6F A;  3PM9 A;  5ADZ A;  3AN1 A;  3FW7 A;  2VAO A;  2Y4G A;  5FXD A;  3D2J A;  1AHU A;  2Q85 A;  3B9J B;  3HSU A;  1ZR6 A;  3RJ8 A;  5AWV A;  3AMZ A;  3S1F A;  2Y3R A;  1WVF A;  4BC7 A;  1DII A;  3TX1 A;  4PZF A;  1W1J A;  1N5X A;  2W55 A;  3ETR B;  3NRZ B;  1W1R A;  4PYT A;  3GSY A;  3S1E A;  4ZOH B;  1N60 C; 
#chains in the Genus database with same CATH topology
 5AE3 A;  4BC9 A;  5HMR A;  5G5G B;  1W1Q A;  1FO4 A;  1FFU C;  1N63 C;  4PWC A;  1RM6 B;  3W8Z A;  2Y3S A;  1AHV A;  3S1C A;  1AHZ A;  2OAI A;  2BVH A;  3EJD B;  3EJB B;  2UUU A;  5I1V A;  2QPM A;  3JS8 A;  4BBY A;  1HSK A;  2EXR A;  4PVK A;  1N5W C;  2Y08 A;  2VFT A;  4DNS A;  4JAY A;  3NVW B;  1VDV A;  2VFS A;  3LLB A;  5I1W A;  2BVF A;  5K8E A;  1W1K A;  5G5H B;  2O3G A;  1MBB A;  1QLU A;  5FXE A;  2QKN A;  3BW7 A;  4PVE A;  5L6G A;  1F0X A;  3I99 A;  3D2H A;  3DED A;  2VFU A;  1E8H A;  2UUV A;  3RJA A;  2AXR A;  4UD8 A;  5HQX A;  5FXP A;  5AE1 A;  3FW8 A;  4O95 A;  4HG0 A;  2MBR A;  2I0K A;  2W3S A;  1E8G A;  1V97 A;  2E3T A;  1N62 C;  3NS1 B;  2P13 A;  1WYG A;  1E8F A;  2GQT A;  5AE2 A;  2P3H A;  1JRP A;  2IPI A;  4JB1 A;  4EC3 A;  4OAL A;  4PVH A;  1W1S A;  3S1D A;  1DIQ A;  2R8D A;  2WDW A;  4XLO A;  1WVE A;  1I19 A;  3PQB A;  1W1L A;  1W1M A;  1FFV C;  4PWB A;  1VAO A;  4PVJ A;  2W3R A;  2YVS A;  2Q4W A;  4ML8 A;  3D2D A;  3NVV B;  4MLA A;  3TSH A;  1N61 C;  5HHZ A;  2VFV A;  3W8W A;  1DZN A;  5FXF A;  3AM9 A;  1T3Q C;  3NVY B;  3TSJ A;  2NQW A;  1ZXI C;  2VFR A;  5D79 A;  1MBT A;  2RK5 A;  1FIQ B;  2GQU A;  3C0P A;  3W8X A;  1SB3 B;  3EUB 3;  3KJM A;  1UXY A;  1JRO A;  2BVG A;  1E0Y A;  1W1O A;  3DQ0 A;  3FWA A;  1QLT A;  4BCA A;  3VTE A;  2W54 A;  3POP A;  3NVZ B;  3FW9 A;  3SR6 B;  5L6F A;  3PM9 A;  3LAE A;  5ADZ A;  2PLS A;  3AN1 A;  3FW7 A;  2VAO A;  2P4P A;  2Y4G A;  3HRD C;  3EJE B;  5FXD A;  3D2J A;  1AHU A;  2Q85 A;  2PLI A;  2R2Z A;  3B9J B;  3HSU A;  1ZR6 A;  3RJ8 A;  5AWV A;  3AMZ A;  3S1F A;  2Y3R A;  1WVF A;  4BC7 A;  1DII A;  3TX1 A;  4PZF A;  1W1J A;  1N5X A;  2W55 A;  3ETR B;  3NRZ B;  1W1R A;  4PYT A;  3GSY A;  3S1E A;  4ZOH B;  1N60 C; 
#chains in the Genus database with same CATH homology
 5AE3 A;  4BC9 A;  5HMR A;  5G5G B;  1W1Q A;  1FO4 A;  1FFU C;  1N63 C;  4PWC A;  1RM6 B;  3W8Z A;  2Y3S A;  1AHV A;  3S1C A;  1AHZ A;  2OAI A;  2BVH A;  2UUU A;  5I1V A;  2QPM A;  3JS8 A;  4BBY A;  1HSK A;  2EXR A;  4PVK A;  1N5W C;  2Y08 A;  2VFT A;  4DNS A;  4JAY A;  3NVW B;  1VDV A;  2VFS A;  3LLB A;  5I1W A;  2BVF A;  5K8E A;  1W1K A;  5G5H B;  2O3G A;  1MBB A;  1QLU A;  5FXE A;  2QKN A;  3BW7 A;  4PVE A;  5L6G A;  1F0X A;  3I99 A;  3D2H A;  3DED A;  2VFU A;  1E8H A;  2UUV A;  3RJA A;  2AXR A;  4UD8 A;  5HQX A;  5FXP A;  5AE1 A;  3FW8 A;  4O95 A;  4HG0 A;  2MBR A;  2I0K A;  2W3S A;  1E8G A;  1V97 A;  2E3T A;  1N62 C;  3NS1 B;  2P13 A;  1WYG A;  1E8F A;  2GQT A;  5AE2 A;  2P3H A;  1JRP A;  2IPI A;  4JB1 A;  4EC3 A;  4OAL A;  4PVH A;  1W1S A;  3S1D A;  1DIQ A;  2R8D A;  2WDW A;  4XLO A;  1WVE A;  1I19 A;  3PQB A;  1W1L A;  1W1M A;  1FFV C;  4PWB A;  1VAO A;  4PVJ A;  2W3R A;  2YVS A;  2Q4W A;  4ML8 A;  3D2D A;  3NVV B;  4MLA A;  3TSH A;  1N61 C;  5HHZ A;  2VFV A;  3W8W A;  1DZN A;  5FXF A;  3AM9 A;  1T3Q C;  3NVY B;  3TSJ A;  2NQW A;  1ZXI C;  2VFR A;  5D79 A;  1MBT A;  2RK5 A;  1FIQ B;  2GQU A;  3C0P A;  3W8X A;  1SB3 B;  3EUB 3;  3KJM A;  1UXY A;  1JRO A;  2BVG A;  1E0Y A;  1W1O A;  3DQ0 A;  3FWA A;  1QLT A;  4BCA A;  3VTE A;  2W54 A;  3POP A;  3NVZ B;  3FW9 A;  3SR6 B;  5L6F A;  3PM9 A;  3LAE A;  5ADZ A;  2PLS A;  3AN1 A;  3FW7 A;  2VAO A;  2P4P A;  2Y4G A;  3HRD C;  5FXD A;  3D2J A;  1AHU A;  2Q85 A;  2PLI A;  2R2Z A;  3B9J B;  3HSU A;  1ZR6 A;  3RJ8 A;  5AWV A;  3AMZ A;  3S1F A;  2Y3R A;  1WVF A;  4BC7 A;  1DII A;  3TX1 A;  4PZF A;  1W1J A;  1N5X A;  2W55 A;  3ETR B;  3NRZ B;  1W1R A;  4PYT A;  3GSY A;  3S1E A;  4ZOH B;  1N60 C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...