3VTEA

Crystal structure of tetrahydrocannabinolic acid synthase from cannabis sativa
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
518
structure length
502
Chain Sequence
ANPRENFLKCFSKHIPNPKLVYTQHDQLYMSILNSTIQNLRFISDTTPKPLVIVTPSNNSHIQATILCSKKVGLQIRTRSGGHDAEGMSYISQVPFVVVDLRNMHSIKIDVHSQTAWVEAGATLGEVYYWINEKNENLSFPGGYCPTVGVGGHFSGGGYGALMRNYGLAADNIIDAHLVNVDGKVLDRKSMGEDLFWAIRGGGGENFGIIAAWKIKLVAVPSKSTIFSVKKNMEIHGLVKLFNKWQNIAYKYDKDLVLMTHFITKNITTTVHGYFSSIFHGGVDSLVDLMNKSFPELGIKKTDCKEFSWIDTTIFYSGVVNFKKEILLDRSAGKKTAFSIKLDYVKKPIPETAMVKILEKLYEEDVGAGMYVLYPYGGIMEEISESAIPFPHRAGIMYELWYTASWEKQEDNEKHINWVRSVYNFTTPYVSQNPRLAYLNYRDLDLGKTNHASPNNYTQARIWGEKYFGKNFNRLVKVKTKVDPNNFFRNEQSIPPLPPHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and function of 1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa
pubmed doi rcsb
source organism Cannabis sativa
molecule tags Oxidoreductase
molecule keywords Tetrahydrocannabinolic acid synthase
total genus 159
structure length 502
sequence length 518
ec nomenclature ec 1.21.3.7: Tetrahydrocannabinolic acid synthase.
pdb deposition date 2012-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3vteA01
3.30.465.50 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3vteA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3vteA03
4PWBA 3BW7A 5AE3A 3D2JA 1W1LA 1VDVA 1V97A 3FW8A 2VFTA 5K8EA 3SR6B 1JROA 3W8WA 4PVKA 5D79A 3I99A 4PWCA 3W8ZA 3PQBA 3TX1A 1UXYA 1W1OA 2VFSA 1DIIA 2EXRA 1DIQA 2VFRA 1DZNA 1AHUA 3FW9A 4PVJA 1W1SA 3ETRB 1AHZA 2VFUA 5ADZA 3FW7A 4BBYA 4OALA 5L6GA 5FXPA 3TSJA 2W3RA 3D2HA 3PM9A 3AN1A 1WVEA 3HSUA 1E8FA 4PVHA 2Y08A 1N5XA 4XLOA 2BVGA 1QLTA 4UD8A 2BVHA 2QPMA 3NVZB 3RJAA 1AHVA 1FIQB 4PYTA 3S1CA 1FFUC 2E3TA 3EUB3 4JB1A 2GQTA 4BC7A 1MBBA 1W1KA 1MBTA 1W1QA 3POPA 5L6FA 4MLAA 3DQ0A 1N63C 4ZOHB 3W8XA 4BC9A 2Q4WA 4O95A 5HQXA 1I19A 1QLUA 1VAOA 2W54A 2IPIA 5AWVA 2GQUA 3D2DA 3AMZA 1T3QC 5FXFA 2W55A 2Y3RA 1E0YA 2Y3SA 4PZFA 3S1EA 1N60C 1W1JA 1WVFA 4JAYA 2I0KA 2Q85A 3S1FA 1HSKA 3C0PA 3NS1B 3B9JB 2BVFA 2Y4GA 3KJMA 1N61C 3GSYA 2VFVA 1FFVC 3FWAA 5I1VA 2W3SA 1N5WC 2AXRA 2MBRA 3NRZB 4DNSA 1WYGA 4ML8A 5FXEA 3TSHA 1ZXIC 5AE1A 5HHZA 5HMRA 2WDWA 3JS8A 1W1MA 1W1RA 1E8GA 3RJ8A 3S1DA 5AE2A 3VTEA 5I1WA 4PVEA 4EC3A 5FXDA 1F0XA 1FO4A 1ZR6A 1N62C 1E8HA 2QKNA 3AM9A 2VAOA 4BCAA
chains in the Genus database with same CATH superfamily
2NQWA 4PWBA 3BW7A 5AE3A 3D2JA 1W1LA 1VDVA 1V97A 3FW8A 2OAIA 2VFTA 2R8DA 5K8EA 3SR6B 1JROA 3EJEB 3W8WA 4PVKA 5D79A 1RM6B 3I99A 4PWCA 3W8ZA 3PQBA 3TX1A 1UXYA 1W1OA 2VFSA 1DIIA 2EXRA 1DIQA 2VFRA 1DZNA 2RK5A 1AHUA 2O3GA 5G5GB 3FW9A 4PVJA 1W1SA 3ETRB 1AHZA 2VFUA 5ADZA 3FW7A 3EJBB 4BBYA 4OALA 3LLBA 5L6GA 5FXPA 3TSJA 2W3RA 3D2HA 3PM9A 3NVVB 3AN1A 2P3HA 1WVEA 3HSUA 1E8FA 4PVHA 2PLIA 2Y08A 1N5XA 4XLOA 2BVGA 1QLTA 4UD8A 2BVHA 2QPMA 3NVZB 3RJAA 1AHVA 1FIQB 4PYTA 3S1CA 1FFUC 2E3TA 3EUB3 4JB1A 2GQTA 4BC7A 1MBBA 1W1KA 1MBTA 1W1QA 3POPA 5L6FA 4HG0A 4MLAA 3DQ0A 1N63C 4ZOHB 3W8XA 4BC9A 2Q4WA 4O95A 5HQXA 1I19A 1QLUA 1VAOA 2W54A 2IPIA 5AWVA 2GQUA 3D2DA 3AMZA 2UUUA 1T3QC 5FXFA 2W55A 2UUVA 2Y3RA 2P4PA 1E0YA 2Y3SA 4PZFA 3S1EA 1N60C 1W1JA 1WVFA 4JAYA 2I0KA 2Q85A 3S1FA 1HSKA 3C0PA 3NS1B 3B9JB 1JRPA 2BVFA 3HRDC 2Y4GA 3DEDA 1SB3B 3KJMA 1N61C 2YVSA 3GSYA 2VFVA 1FFVC 3FWAA 5I1VA 2W3SA 1N5WC 2AXRA 3NVYB 3EJDB 2MBRA 3NRZB 4DNSA 1WYGA 4ML8A 5FXEA 2P13A 3TSHA 2R2ZA 1ZXIC 5AE1A 5HHZA 5HMRA 2WDWA 5G5HB 3JS8A 1W1MA 1W1RA 1E8GA 3RJ8A 2PLSA 3S1DA 5AE2A 3VTEA 5I1WA 4PVEA 4EC3A 5FXDA 1F0XA 1FO4A 1ZR6A 1N62C 1E8HA 2QKNA 3NVWB 3AM9A 3LAEA 2VAOA 4BCAA
chains in the Genus database with same CATH topology
2NQWA 4PWBA 3BW7A 5AE3A 3D2JA 1W1LA 1VDVA 1V97A 3FW8A 2OAIA 2VFTA 2R8DA 5K8EA 3SR6B 1JROA 3W8WA 4PVKA 5D79A 1RM6B 3I99A 4PWCA 3W8ZA 3PQBA 3TX1A 1UXYA 1W1OA 2VFSA 1DIIA 2EXRA 1DIQA 2VFRA 1DZNA 2RK5A 1AHUA 2O3GA 5G5GB 3FW9A 4PVJA 1W1SA 3ETRB 1AHZA 2VFUA 5ADZA 3FW7A 4BBYA 4OALA 3LLBA 5L6GA 5FXPA 3TSJA 2W3RA 3D2HA 3PM9A 3NVVB 3AN1A 2P3HA 1WVEA 3HSUA 1E8FA 4PVHA 2PLIA 2Y08A 1N5XA 4XLOA 2BVGA 1QLTA 4UD8A 2BVHA 2QPMA 3NVZB 3RJAA 1AHVA 1FIQB 4PYTA 3S1CA 1FFUC 2E3TA 3EUB3 4JB1A 2GQTA 4BC7A 1MBBA 1W1KA 1MBTA 1W1QA 3POPA 5L6FA 4HG0A 4MLAA 3DQ0A 1N63C 4ZOHB 3W8XA 4BC9A 2Q4WA 4O95A 5HQXA 1I19A 1QLUA 1VAOA 2W54A 2IPIA 5AWVA 2GQUA 3D2DA 3AMZA 2UUUA 1T3QC 5FXFA 2W55A 2UUVA 2Y3RA 2P4PA 1E0YA 2Y3SA 4PZFA 3S1EA 1N60C 1W1JA 1WVFA 4JAYA 2I0KA 2Q85A 3S1FA 1HSKA 3C0PA 3NS1B 3B9JB 1JRPA 2BVFA 3HRDC 2Y4GA 3DEDA 1SB3B 3KJMA 1N61C 2YVSA 3GSYA 2VFVA 1FFVC 3FWAA 5I1VA 2W3SA 1N5WC 2AXRA 3NVYB 2MBRA 3NRZB 4DNSA 1WYGA 4ML8A 5FXEA 2P13A 3TSHA 2R2ZA 1ZXIC 5AE1A 5HHZA 5HMRA 2WDWA 5G5HB 3JS8A 1W1MA 1W1RA 1E8GA 3RJ8A 2PLSA 3S1DA 5AE2A 3VTEA 5I1WA 4PVEA 4EC3A 5FXDA 1F0XA 1FO4A 1ZR6A 1N62C 1E8HA 2QKNA 3LAEA 3AM9A 3NVWB 2VAOA 4BCAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PWB A;  3BW7 A;  5AE3 A;  3D2J A;  1W1L A;  1VDV A;  1V97 A;  3FW8 A;  2VFT A;  5K8E A;  3SR6 B;  1JRO A;  3W8W A;  4PVK A;  5D79 A;  3I99 A;  4PWC A;  3W8Z A;  3PQB A;  3TX1 A;  1UXY A;  1W1O A;  2VFS A;  1DII A;  2EXR A;  1DIQ A;  2VFR A;  1DZN A;  1AHU A;  3FW9 A;  4PVJ A;  1W1S A;  3ETR B;  1AHZ A;  2VFU A;  5ADZ A;  3FW7 A;  4BBY A;  4OAL A;  5L6G A;  5FXP A;  3TSJ A;  2W3R A;  3D2H A;  3PM9 A;  3AN1 A;  1WVE A;  3HSU A;  1E8F A;  4PVH A;  2Y08 A;  1N5X A;  4XLO A;  2BVG A;  1QLT A;  4UD8 A;  2BVH A;  2QPM A;  3NVZ B;  3RJA A;  1AHV A;  1FIQ B;  4PYT A;  3S1C A;  1FFU C;  2E3T A;  3EUB 3;  4JB1 A;  2GQT A;  4BC7 A;  1MBB A;  1W1K A;  1MBT A;  1W1Q A;  3POP A;  5L6F A;  4MLA A;  3DQ0 A;  1N63 C;  4ZOH B;  3W8X A;  4BC9 A;  2Q4W A;  4O95 A;  5HQX A;  1I19 A;  1QLU A;  1VAO A;  2W54 A;  2IPI A;  5AWV A;  2GQU A;  3D2D A;  3AMZ A;  1T3Q C;  5FXF A;  2W55 A;  2Y3R A;  1E0Y A;  2Y3S A;  4PZF A;  3S1E A;  1N60 C;  1W1J A;  1WVF A;  4JAY A;  2I0K A;  2Q85 A;  3S1F A;  1HSK A;  3C0P A;  3NS1 B;  3B9J B;  2BVF A;  2Y4G A;  3KJM A;  1N61 C;  3GSY A;  2VFV A;  1FFV C;  3FWA A;  5I1V A;  2W3S A;  1N5W C;  2AXR A;  2MBR A;  3NRZ B;  4DNS A;  1WYG A;  4ML8 A;  5FXE A;  3TSH A;  1ZXI C;  5AE1 A;  5HHZ A;  5HMR A;  2WDW A;  3JS8 A;  1W1M A;  1W1R A;  1E8G A;  3RJ8 A;  3S1D A;  5AE2 A;  3VTE A;  5I1W A;  4PVE A;  4EC3 A;  5FXD A;  1F0X A;  1FO4 A;  1ZR6 A;  1N62 C;  1E8H A;  2QKN A;  3AM9 A;  2VAO A;  4BCA A; 
#chains in the Genus database with same CATH topology
 2NQW A;  4PWB A;  3BW7 A;  5AE3 A;  3D2J A;  1W1L A;  1VDV A;  1V97 A;  3FW8 A;  2OAI A;  2VFT A;  2R8D A;  5K8E A;  3SR6 B;  1JRO A;  3EJE B;  3W8W A;  4PVK A;  5D79 A;  1RM6 B;  3I99 A;  4PWC A;  3W8Z A;  3PQB A;  3TX1 A;  1UXY A;  1W1O A;  2VFS A;  1DII A;  2EXR A;  1DIQ A;  2VFR A;  1DZN A;  2RK5 A;  1AHU A;  2O3G A;  5G5G B;  3FW9 A;  4PVJ A;  1W1S A;  3ETR B;  1AHZ A;  2VFU A;  5ADZ A;  3FW7 A;  3EJB B;  4BBY A;  4OAL A;  3LLB A;  5L6G A;  5FXP A;  3TSJ A;  2W3R A;  3D2H A;  3PM9 A;  3NVV B;  3AN1 A;  2P3H A;  1WVE A;  3HSU A;  1E8F A;  4PVH A;  2PLI A;  2Y08 A;  1N5X A;  4XLO A;  2BVG A;  1QLT A;  4UD8 A;  2BVH A;  2QPM A;  3NVZ B;  3RJA A;  1AHV A;  1FIQ B;  4PYT A;  3S1C A;  1FFU C;  2E3T A;  3EUB 3;  4JB1 A;  2GQT A;  4BC7 A;  1MBB A;  1W1K A;  1MBT A;  1W1Q A;  3POP A;  5L6F A;  4HG0 A;  4MLA A;  3DQ0 A;  1N63 C;  4ZOH B;  3W8X A;  4BC9 A;  2Q4W A;  4O95 A;  5HQX A;  1I19 A;  1QLU A;  1VAO A;  2W54 A;  2IPI A;  5AWV A;  2GQU A;  3D2D A;  3AMZ A;  2UUU A;  1T3Q C;  5FXF A;  2W55 A;  2UUV A;  2Y3R A;  2P4P A;  1E0Y A;  2Y3S A;  4PZF A;  3S1E A;  1N60 C;  1W1J A;  1WVF A;  4JAY A;  2I0K A;  2Q85 A;  3S1F A;  1HSK A;  3C0P A;  3NS1 B;  3B9J B;  1JRP A;  2BVF A;  3HRD C;  2Y4G A;  3DED A;  1SB3 B;  3KJM A;  1N61 C;  2YVS A;  3GSY A;  2VFV A;  1FFV C;  3FWA A;  5I1V A;  2W3S A;  1N5W C;  2AXR A;  3NVY B;  3EJD B;  2MBR A;  3NRZ B;  4DNS A;  1WYG A;  4ML8 A;  5FXE A;  2P13 A;  3TSH A;  2R2Z A;  1ZXI C;  5AE1 A;  5HHZ A;  5HMR A;  2WDW A;  5G5H B;  3JS8 A;  1W1M A;  1W1R A;  1E8G A;  3RJ8 A;  2PLS A;  3S1D A;  5AE2 A;  3VTE A;  5I1W A;  4PVE A;  4EC3 A;  5FXD A;  1F0X A;  1FO4 A;  1ZR6 A;  1N62 C;  1E8H A;  2QKN A;  3NVW B;  3AM9 A;  3LAE A;  2VAO A;  4BCA A; 
#chains in the Genus database with same CATH homology
 2NQW A;  4PWB A;  3BW7 A;  5AE3 A;  3D2J A;  1W1L A;  1VDV A;  1V97 A;  3FW8 A;  2OAI A;  2VFT A;  2R8D A;  5K8E A;  3SR6 B;  1JRO A;  3W8W A;  4PVK A;  5D79 A;  1RM6 B;  3I99 A;  4PWC A;  3W8Z A;  3PQB A;  3TX1 A;  1UXY A;  1W1O A;  2VFS A;  1DII A;  2EXR A;  1DIQ A;  2VFR A;  1DZN A;  2RK5 A;  1AHU A;  2O3G A;  5G5G B;  3FW9 A;  4PVJ A;  1W1S A;  3ETR B;  1AHZ A;  2VFU A;  5ADZ A;  3FW7 A;  4BBY A;  4OAL A;  3LLB A;  5L6G A;  5FXP A;  3TSJ A;  2W3R A;  3D2H A;  3PM9 A;  3NVV B;  3AN1 A;  2P3H A;  1WVE A;  3HSU A;  1E8F A;  4PVH A;  2PLI A;  2Y08 A;  1N5X A;  4XLO A;  2BVG A;  1QLT A;  4UD8 A;  2BVH A;  2QPM A;  3NVZ B;  3RJA A;  1AHV A;  1FIQ B;  4PYT A;  3S1C A;  1FFU C;  2E3T A;  3EUB 3;  4JB1 A;  2GQT A;  4BC7 A;  1MBB A;  1W1K A;  1MBT A;  1W1Q A;  3POP A;  5L6F A;  4HG0 A;  4MLA A;  3DQ0 A;  1N63 C;  4ZOH B;  3W8X A;  4BC9 A;  2Q4W A;  4O95 A;  5HQX A;  1I19 A;  1QLU A;  1VAO A;  2W54 A;  2IPI A;  5AWV A;  2GQU A;  3D2D A;  3AMZ A;  2UUU A;  1T3Q C;  5FXF A;  2W55 A;  2UUV A;  2Y3R A;  2P4P A;  1E0Y A;  2Y3S A;  4PZF A;  3S1E A;  1N60 C;  1W1J A;  1WVF A;  4JAY A;  2I0K A;  2Q85 A;  3S1F A;  1HSK A;  3C0P A;  3NS1 B;  3B9J B;  1JRP A;  2BVF A;  3HRD C;  2Y4G A;  3DED A;  1SB3 B;  3KJM A;  1N61 C;  2YVS A;  3GSY A;  2VFV A;  1FFV C;  3FWA A;  5I1V A;  2W3S A;  1N5W C;  2AXR A;  3NVY B;  2MBR A;  3NRZ B;  4DNS A;  1WYG A;  4ML8 A;  5FXE A;  2P13 A;  3TSH A;  2R2Z A;  1ZXI C;  5AE1 A;  5HHZ A;  5HMR A;  2WDW A;  5G5H B;  3JS8 A;  1W1M A;  1W1R A;  1E8G A;  3RJ8 A;  2PLS A;  3S1D A;  5AE2 A;  3VTE A;  5I1W A;  4PVE A;  4EC3 A;  5FXD A;  1F0X A;  1FO4 A;  1ZR6 A;  1N62 C;  1E8H A;  2QKN A;  3LAE A;  3AM9 A;  3NVW B;  2VAO A;  4BCA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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