3W8ZA

The complex structure of encm with hydroxytetraketide
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
460
structure length
460
Chain Sequence
QFPQLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Putative FAD-dependent oxygenase EncM
publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
source organism Streptomyces maritimus
molecule tags Oxidoreductase
total genus 139
structure length 460
sequence length 460
chains with identical sequence B
ec nomenclature ec 1.13.12.-:
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3w8zA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3w8zA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3w8zA03
4PYTA 4O95A 5ADZA 3W8ZA 1DIIA 3AMZA 3NVYB 1JRPA 5FXDA 4BCAA 2VFRA 3NVZB 2W3SA 1AHVA 1W1KA 2YVSA 2NQWA 4XLOA 3GSYA 3NVVB 3NRZB 2I0KA 1W1MA 1W1RA 1W1QA 1DZNA 4ML8A 5HQXA 5I1WA 1T3QC 1QLUA 3FW7A 2RK5A 1FFVC 1JROA 1F0XA 5HMRA 4OALA 5D79A 2BVGA 1W1LA 2E3TA 5AE2A 5I1VA 2Q4WA 2GQTA 3FW9A 2Y08A 5L6GA 3LAEA 5G5GB 2Q85A 1E8GA 4PZFA 3TSJA 3NVWB 1ZXIC 3FWAA 1N5WC 3KJMA 1ZR6A 1VDVA 3TX1A 4HG0A 1N63C 3B9JB 4BBYA 3D2JA 2W54A 2W3RA 1N62C 3ETRB 3DQ0A 3AM9A 5AE1A 3HSUA 2OAIA 3C0PA 4PVJA 5AWVA 4DNSA 2VFUA 2BVHA 2QKNA 3PQBA 2R8DA 3D2DA 2VFVA 5L6FA 2PLIA 1AHZA 2Y3RA 3EUB3 1V97A 1W1OA 3NS1B 3TSHA 3AN1A 5G5HB 1FO4A 1MBTA 2W55A 3VTEA 5FXFA 5FXPA 4PVEA 3BW7A 5K8EA 3PM9A 1E8FA 4MLAA 4UD8A 1SB3B 1N60C 4PVKA 2AXRA 1FFUC 1WYGA 5FXEA 3S1EA 4BC7A 2R2ZA 2P3HA 2O3GA 3JS8A 3S1FA 4PWCA 1W1SA 2VFTA 3I99A 2IPIA 2P4PA 3S1CA 2BVFA 4PWBA 1DIQA 2Y4GA 1RM6B 1E8HA 3SR6B 1HSKA 4BC9A 3POPA 3HRDC 3RJ8A 2MBRA 1FIQB 5AE3A 3RJAA 3LLBA 3D2HA 5HHZA 4JB1A 3W8XA 2QPMA 2Y3SA 1MBBA 1WVEA 1AHUA 2P13A 1W1JA 3FW8A 1N5XA 2EXRA 2PLSA 3W8WA 1N61C 1WVFA 3DEDA 2WDWA 1VAOA 3S1DA 4JAYA 1QLTA 1I19A 1UXYA 4PVHA 2VAOA 4ZOHB 4EC3A 2VFSA 2GQUA 1E0YA
chains in the Genus database with same CATH superfamily
4PYTA 4O95A 5ADZA 3W8ZA 1DIIA 3AMZA 3NVYB 1JRPA 5FXDA 4BCAA 2VFRA 3NVZB 2W3SA 1AHVA 1W1KA 2YVSA 2NQWA 4XLOA 3GSYA 3NVVB 3EJEB 3NRZB 2I0KA 1W1MA 1W1RA 1W1QA 1DZNA 4ML8A 5HQXA 5I1WA 1T3QC 1QLUA 3FW7A 2RK5A 1FFVC 1JROA 1F0XA 5HMRA 4OALA 5D79A 2BVGA 1W1LA 2E3TA 5AE2A 5I1VA 2Q4WA 2GQTA 3FW9A 2Y08A 5L6GA 3LAEA 5G5GB 2Q85A 1E8GA 4PZFA 3NVWB 3TSJA 1ZXIC 3FWAA 1N5WC 3KJMA 1ZR6A 1VDVA 3TX1A 4HG0A 1N63C 3B9JB 3EJBB 4BBYA 3D2JA 2W54A 2W3RA 1N62C 3ETRB 3DQ0A 3AM9A 5AE1A 3HSUA 2OAIA 3C0PA 4PVJA 5AWVA 4DNSA 2VFUA 2BVHA 3EJDB 2QKNA 3PQBA 2R8DA 3D2DA 2VFVA 5L6FA 2PLIA 1AHZA 2Y3RA 3EUB3 1V97A 1W1OA 3NS1B 3TSHA 3AN1A 5G5HB 1FO4A 1MBTA 2W55A 3VTEA 5FXFA 5FXPA 4PVEA 3BW7A 5K8EA 3PM9A 1E8FA 4MLAA 4UD8A 1SB3B 1N60C 4PVKA 2AXRA 1FFUC 1WYGA 5FXEA 3S1EA 4BC7A 2R2ZA 2UUUA 2UUVA 2P3HA 2O3GA 3JS8A 3S1FA 4PWCA 1W1SA 2VFTA 3I99A 2IPIA 2P4PA 3S1CA 2BVFA 4PWBA 1DIQA 2Y4GA 1RM6B 1E8HA 3SR6B 1HSKA 4BC9A 3POPA 3HRDC 3RJ8A 2MBRA 1FIQB 5AE3A 3RJAA 3LLBA 3D2HA 5HHZA 4JB1A 3W8XA 2QPMA 2Y3SA 1MBBA 1WVEA 1AHUA 2P13A 1W1JA 3FW8A 1N5XA 2EXRA 2PLSA 3W8WA 1N61C 1WVFA 2WDWA 3DEDA 1VAOA 3S1DA 4JAYA 1QLTA 1I19A 1UXYA 4PVHA 2VAOA 4ZOHB 4EC3A 2VFSA 2GQUA 1E0YA
chains in the Genus database with same CATH topology
4PYTA 4O95A 5ADZA 3W8ZA 1DIIA 3AMZA 3NVYB 1JRPA 5FXDA 4BCAA 2VFRA 3NVZB 2W3SA 1AHVA 1W1KA 2YVSA 2NQWA 4XLOA 3GSYA 3NVVB 3NRZB 2I0KA 1W1MA 1W1RA 1W1QA 1DZNA 4ML8A 5HQXA 5I1WA 1T3QC 1QLUA 3FW7A 2RK5A 1FFVC 1JROA 1F0XA 5HMRA 4OALA 5D79A 2BVGA 1W1LA 2E3TA 5AE2A 5I1VA 2Q4WA 2GQTA 3FW9A 2Y08A 5L6GA 3LAEA 5G5GB 2Q85A 1E8GA 4PZFA 3TSJA 3NVWB 1ZXIC 3FWAA 1N5WC 3KJMA 1ZR6A 1VDVA 3TX1A 4HG0A 1N63C 3B9JB 4BBYA 3D2JA 2W54A 2W3RA 1N62C 3ETRB 3DQ0A 3AM9A 5AE1A 3HSUA 2OAIA 3C0PA 4PVJA 5AWVA 4DNSA 2VFUA 2BVHA 2QKNA 3PQBA 2R8DA 3D2DA 2VFVA 5L6FA 2PLIA 1AHZA 2Y3RA 3EUB3 1V97A 1W1OA 3NS1B 3TSHA 3AN1A 5G5HB 1FO4A 1MBTA 2W55A 3VTEA 5FXFA 5FXPA 4PVEA 3BW7A 5K8EA 3PM9A 1E8FA 4MLAA 4UD8A 1SB3B 1N60C 4PVKA 2AXRA 1FFUC 1WYGA 5FXEA 3S1EA 4BC7A 2R2ZA 2UUUA 2UUVA 2P3HA 2O3GA 3JS8A 3S1FA 4PWCA 1W1SA 2VFTA 3I99A 2IPIA 2P4PA 3S1CA 2BVFA 4PWBA 1DIQA 2Y4GA 1RM6B 1E8HA 3SR6B 1HSKA 4BC9A 3POPA 3HRDC 3RJ8A 2MBRA 1FIQB 5AE3A 3RJAA 3LLBA 3D2HA 5HHZA 4JB1A 3W8XA 2QPMA 2Y3SA 1MBBA 1WVEA 1AHUA 2P13A 1W1JA 3FW8A 1N5XA 2EXRA 2PLSA 3W8WA 1N61C 1WVFA 2WDWA 3DEDA 1VAOA 3S1DA 4JAYA 1QLTA 1I19A 1UXYA 4PVHA 2VAOA 4ZOHB 4EC3A 2VFSA 2GQUA 1E0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PYT A;  4O95 A;  5ADZ A;  3W8Z A;  1DII A;  3AMZ A;  3NVY B;  1JRP A;  5FXD A;  4BCA A;  2VFR A;  3NVZ B;  2W3S A;  1AHV A;  1W1K A;  2YVS A;  2NQW A;  4XLO A;  3GSY A;  3NVV B;  3NRZ B;  2I0K A;  1W1M A;  1W1R A;  1W1Q A;  1DZN A;  4ML8 A;  5HQX A;  5I1W A;  1T3Q C;  1QLU A;  3FW7 A;  2RK5 A;  1FFV C;  1JRO A;  1F0X A;  5HMR A;  4OAL A;  5D79 A;  2BVG A;  1W1L A;  2E3T A;  5AE2 A;  5I1V A;  2Q4W A;  2GQT A;  3FW9 A;  2Y08 A;  5L6G A;  3LAE A;  5G5G B;  2Q85 A;  1E8G A;  4PZF A;  3TSJ A;  3NVW B;  1ZXI C;  3FWA A;  1N5W C;  3KJM A;  1ZR6 A;  1VDV A;  3TX1 A;  4HG0 A;  1N63 C;  3B9J B;  4BBY A;  3D2J A;  2W54 A;  2W3R A;  1N62 C;  3ETR B;  3DQ0 A;  3AM9 A;  5AE1 A;  3HSU A;  2OAI A;  3C0P A;  4PVJ A;  5AWV A;  4DNS A;  2VFU A;  2BVH A;  2QKN A;  3PQB A;  2R8D A;  3D2D A;  2VFV A;  5L6F A;  2PLI A;  1AHZ A;  2Y3R A;  3EUB 3;  1V97 A;  1W1O A;  3NS1 B;  3TSH A;  3AN1 A;  5G5H B;  1FO4 A;  1MBT A;  2W55 A;  3VTE A;  5FXF A;  5FXP A;  4PVE A;  3BW7 A;  5K8E A;  3PM9 A;  1E8F A;  4MLA A;  4UD8 A;  1SB3 B;  1N60 C;  4PVK A;  2AXR A;  1FFU C;  1WYG A;  5FXE A;  3S1E A;  4BC7 A;  2R2Z A;  2P3H A;  2O3G A;  3JS8 A;  3S1F A;  4PWC A;  1W1S A;  2VFT A;  3I99 A;  2IPI A;  2P4P A;  3S1C A;  2BVF A;  4PWB A;  1DIQ A;  2Y4G A;  1RM6 B;  1E8H A;  3SR6 B;  1HSK A;  4BC9 A;  3POP A;  3HRD C;  3RJ8 A;  2MBR A;  1FIQ B;  5AE3 A;  3RJA A;  3LLB A;  3D2H A;  5HHZ A;  4JB1 A;  3W8X A;  2QPM A;  2Y3S A;  1MBB A;  1WVE A;  1AHU A;  2P13 A;  1W1J A;  3FW8 A;  1N5X A;  2EXR A;  2PLS A;  3W8W A;  1N61 C;  1WVF A;  3DED A;  2WDW A;  1VAO A;  3S1D A;  4JAY A;  1QLT A;  1I19 A;  1UXY A;  4PVH A;  2VAO A;  4ZOH B;  4EC3 A;  2VFS A;  2GQU A;  1E0Y A; 
#chains in the Genus database with same CATH topology
 4PYT A;  4O95 A;  5ADZ A;  3W8Z A;  1DII A;  3AMZ A;  3NVY B;  1JRP A;  5FXD A;  4BCA A;  2VFR A;  3NVZ B;  2W3S A;  1AHV A;  1W1K A;  2YVS A;  2NQW A;  4XLO A;  3GSY A;  3NVV B;  3EJE B;  3NRZ B;  2I0K A;  1W1M A;  1W1R A;  1W1Q A;  1DZN A;  4ML8 A;  5HQX A;  5I1W A;  1T3Q C;  1QLU A;  3FW7 A;  2RK5 A;  1FFV C;  1JRO A;  1F0X A;  5HMR A;  4OAL A;  5D79 A;  2BVG A;  1W1L A;  2E3T A;  5AE2 A;  5I1V A;  2Q4W A;  2GQT A;  3FW9 A;  2Y08 A;  5L6G A;  3LAE A;  5G5G B;  2Q85 A;  1E8G A;  4PZF A;  3NVW B;  3TSJ A;  1ZXI C;  3FWA A;  1N5W C;  3KJM A;  1ZR6 A;  1VDV A;  3TX1 A;  4HG0 A;  1N63 C;  3B9J B;  3EJB B;  4BBY A;  3D2J A;  2W54 A;  2W3R A;  1N62 C;  3ETR B;  3DQ0 A;  3AM9 A;  5AE1 A;  3HSU A;  2OAI A;  3C0P A;  4PVJ A;  5AWV A;  4DNS A;  2VFU A;  2BVH A;  3EJD B;  2QKN A;  3PQB A;  2R8D A;  3D2D A;  2VFV A;  5L6F A;  2PLI A;  1AHZ A;  2Y3R A;  3EUB 3;  1V97 A;  1W1O A;  3NS1 B;  3TSH A;  3AN1 A;  5G5H B;  1FO4 A;  1MBT A;  2W55 A;  3VTE A;  5FXF A;  5FXP A;  4PVE A;  3BW7 A;  5K8E A;  3PM9 A;  1E8F A;  4MLA A;  4UD8 A;  1SB3 B;  1N60 C;  4PVK A;  2AXR A;  1FFU C;  1WYG A;  5FXE A;  3S1E A;  4BC7 A;  2R2Z A;  2UUU A;  2UUV A;  2P3H A;  2O3G A;  3JS8 A;  3S1F A;  4PWC A;  1W1S A;  2VFT A;  3I99 A;  2IPI A;  2P4P A;  3S1C A;  2BVF A;  4PWB A;  1DIQ A;  2Y4G A;  1RM6 B;  1E8H A;  3SR6 B;  1HSK A;  4BC9 A;  3POP A;  3HRD C;  3RJ8 A;  2MBR A;  1FIQ B;  5AE3 A;  3RJA A;  3LLB A;  3D2H A;  5HHZ A;  4JB1 A;  3W8X A;  2QPM A;  2Y3S A;  1MBB A;  1WVE A;  1AHU A;  2P13 A;  1W1J A;  3FW8 A;  1N5X A;  2EXR A;  2PLS A;  3W8W A;  1N61 C;  1WVF A;  2WDW A;  3DED A;  1VAO A;  3S1D A;  4JAY A;  1QLT A;  1I19 A;  1UXY A;  4PVH A;  2VAO A;  4ZOH B;  4EC3 A;  2VFS A;  2GQU A;  1E0Y A; 
#chains in the Genus database with same CATH homology
 4PYT A;  4O95 A;  5ADZ A;  3W8Z A;  1DII A;  3AMZ A;  3NVY B;  1JRP A;  5FXD A;  4BCA A;  2VFR A;  3NVZ B;  2W3S A;  1AHV A;  1W1K A;  2YVS A;  2NQW A;  4XLO A;  3GSY A;  3NVV B;  3NRZ B;  2I0K A;  1W1M A;  1W1R A;  1W1Q A;  1DZN A;  4ML8 A;  5HQX A;  5I1W A;  1T3Q C;  1QLU A;  3FW7 A;  2RK5 A;  1FFV C;  1JRO A;  1F0X A;  5HMR A;  4OAL A;  5D79 A;  2BVG A;  1W1L A;  2E3T A;  5AE2 A;  5I1V A;  2Q4W A;  2GQT A;  3FW9 A;  2Y08 A;  5L6G A;  3LAE A;  5G5G B;  2Q85 A;  1E8G A;  4PZF A;  3TSJ A;  3NVW B;  1ZXI C;  3FWA A;  1N5W C;  3KJM A;  1ZR6 A;  1VDV A;  3TX1 A;  4HG0 A;  1N63 C;  3B9J B;  4BBY A;  3D2J A;  2W54 A;  2W3R A;  1N62 C;  3ETR B;  3DQ0 A;  3AM9 A;  5AE1 A;  3HSU A;  2OAI A;  3C0P A;  4PVJ A;  5AWV A;  4DNS A;  2VFU A;  2BVH A;  2QKN A;  3PQB A;  2R8D A;  3D2D A;  2VFV A;  5L6F A;  2PLI A;  1AHZ A;  2Y3R A;  3EUB 3;  1V97 A;  1W1O A;  3NS1 B;  3TSH A;  3AN1 A;  5G5H B;  1FO4 A;  1MBT A;  2W55 A;  3VTE A;  5FXF A;  5FXP A;  4PVE A;  3BW7 A;  5K8E A;  3PM9 A;  1E8F A;  4MLA A;  4UD8 A;  1SB3 B;  1N60 C;  4PVK A;  2AXR A;  1FFU C;  1WYG A;  5FXE A;  3S1E A;  4BC7 A;  2R2Z A;  2UUU A;  2UUV A;  2P3H A;  2O3G A;  3JS8 A;  3S1F A;  4PWC A;  1W1S A;  2VFT A;  3I99 A;  2IPI A;  2P4P A;  3S1C A;  2BVF A;  4PWB A;  1DIQ A;  2Y4G A;  1RM6 B;  1E8H A;  3SR6 B;  1HSK A;  4BC9 A;  3POP A;  3HRD C;  3RJ8 A;  2MBR A;  1FIQ B;  5AE3 A;  3RJA A;  3LLB A;  3D2H A;  5HHZ A;  4JB1 A;  3W8X A;  2QPM A;  2Y3S A;  1MBB A;  1WVE A;  1AHU A;  2P13 A;  1W1J A;  3FW8 A;  1N5X A;  2EXR A;  2PLS A;  3W8W A;  1N61 C;  1WVF A;  2WDW A;  3DED A;  1VAO A;  3S1D A;  4JAY A;  1QLT A;  1I19 A;  1UXY A;  4PVH A;  2VAO A;  4ZOH B;  4EC3 A;  2VFS A;  2GQU A;  1E0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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