3W8ZA

The complex structure of encm with hydroxytetraketide
Total Genus 139
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
460
structure length
460
Chain Sequence
QFPQLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords Putative FAD-dependent oxygenase EncM
publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
source organism Streptomyces maritimus
total genus 139
structure length 460
sequence length 460
chains with identical sequence B
ec nomenclature ec 1.13.12.-:
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3w8zA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3w8zA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3w8zA03
4ML8A 1AHVA 3W8WA 3TX1A 5G5HB 2O3GA 3FW9A 2W54A 1FFUC 3AN1A 1FO4A 3PQBA 1E8HA 2Q4WA 3TSJA 2PLIA 5AWVA 2MBRA 1N5WC 1N63C 5HQXA 2Y3RA 2VFSA 5I1WA 4MLAA 1AHZA 3NRZB 2RK5A 1ZR6A 1W1LA 1HSKA 2BVHA 1AHUA 3S1CA 1N5XA 5I1VA 2VFRA 3FW7A 4DNSA 1DZNA 1W1OA 3HSUA 1FFVC 4HG0A 1VAOA 1W1RA 3HRDC 1N61C 1ZXIC 3NVYB 1I19A 5FXPA 3JS8A 2QPMA 2VFUA 2W55A 1F0XA 1E8FA 3NVWB 1VDVA 4EC3A 4PVKA 3S1EA 1JRPA 1DIQA 1SB3B 1JROA 2R8DA 5L6FA 2R2ZA 3D2JA 4PVJA 1E8GA 4PVEA 4PVHA 4PWCA 2W3RA 2W3SA 4ZOHB 5AE3A 3S1DA 4PWBA 3AM9A 1DIIA 2NQWA 3ETRB 3TSHA 3POPA 4O95A 1T3QC 5FXFA 1E0YA 1N62C 4PZFA 3SR6B 2BVFA 1MBTA 2AXRA 4UD8A 1N60C 3W8XA 2BVGA 1WVFA 3VTEA 4BC9A 1RM6B 2GQTA 2IPIA 5D79A 2I0KA 2VAOA 2GQUA 1W1MA 1W1SA 3C0PA 4BC7A 5L6GA 3PM9A 4BCAA 2YVSA 5HHZA 2P4PA 2Y08A 1QLTA 1FIQB 3W8ZA 5K8EA 3GSYA 3S1FA 3DEDA 3AMZA 1W1KA 1W1QA 1QLUA 1WVEA 2Q85A 5AE1A 3BW7A 4XLOA 2Y3SA 2P3HA 3D2HA 2OAIA 3D2DA 3DQ0A 1W1JA 2EXRA 1WYGA 3NVZB 3RJ8A 3LLBA 4OALA 4JAYA 5FXDA 4BBYA 2PLSA 2E3TA 3LAEA 3NVVB 5ADZA 1V97A 3KJMA 3EUB3 3FW8A 3RJAA 4JB1A 3NS1B 2VFTA 2QKNA 5G5GB 1UXYA 4PYTA 3B9JB 5HMRA 2VFVA 3FWAA 2P13A 3I99A 5FXEA 5AE2A 2Y4GA 2WDWA 1MBBA
chains in the Genus database with same CATH superfamily
4ML8A 1AHVA 3EJDB 3TX1A 3W8WA 5G5HB 2O3GA 3FW9A 2W54A 1FFUC 3AN1A 1FO4A 3PQBA 2UUUA 1E8HA 2Q4WA 3TSJA 2PLIA 5AWVA 2MBRA 1N5WC 1N63C 5HQXA 2Y3RA 2VFSA 5I1WA 4MLAA 1AHZA 3NRZB 2RK5A 1ZR6A 1W1LA 1HSKA 2BVHA 1AHUA 3S1CA 1N5XA 5I1VA 2VFRA 3FW7A 4DNSA 1DZNA 1W1OA 3HSUA 1FFVC 4HG0A 1VAOA 1W1RA 3HRDC 1N61C 1ZXIC 3NVYB 1I19A 5FXPA 3JS8A 2QPMA 2VFUA 2W55A 1F0XA 1E8FA 3NVWB 1VDVA 4EC3A 4PVKA 3S1EA 1JRPA 1DIQA 1SB3B 1JROA 2R8DA 5L6FA 2R2ZA 3D2JA 4PVJA 1E8GA 4PVEA 4PVHA 4PWCA 2W3RA 2W3SA 4ZOHB 5AE3A 3S1DA 4PWBA 3AM9A 1DIIA 2NQWA 3ETRB 3TSHA 3POPA 4O95A 1T3QC 5FXFA 1E0YA 1N62C 4PZFA 3SR6B 2BVFA 1MBTA 2AXRA 4UD8A 1N60C 3W8XA 2BVGA 1WVFA 3VTEA 4BC9A 1RM6B 2GQTA 2IPIA 5D79A 2I0KA 2VAOA 2GQUA 1W1MA 1W1SA 3C0PA 3EJBB 4BC7A 5L6GA 3PM9A 4BCAA 2YVSA 5HHZA 2P4PA 2Y08A 1QLTA 1FIQB 3W8ZA 5K8EA 3GSYA 3S1FA 3DEDA 3AMZA 1W1KA 1W1QA 1QLUA 1WVEA 2Q85A 5AE1A 3BW7A 4XLOA 2Y3SA 2P3HA 3D2HA 2OAIA 3D2DA 3DQ0A 1W1JA 2EXRA 1WYGA 3NVZB 3RJ8A 3LLBA 4OALA 4JAYA 5FXDA 4BBYA 2PLSA 2E3TA 3LAEA 3NVVB 5ADZA 2UUVA 1V97A 3KJMA 3EJEB 3EUB3 3FW8A 3RJAA 4JB1A 3NS1B 2VFTA 2QKNA 5G5GB 1UXYA 4PYTA 3B9JB 5HMRA 2VFVA 3FWAA 2P13A 3I99A 5FXEA 5AE2A 2Y4GA 2WDWA 1MBBA
chains in the Genus database with same CATH topology
4ML8A 1AHVA 3W8WA 3TX1A 5G5HB 2O3GA 3FW9A 2W54A 1FFUC 3AN1A 1FO4A 3PQBA 2UUUA 1E8HA 2Q4WA 3TSJA 2PLIA 5AWVA 2MBRA 1N5WC 1N63C 5HQXA 2Y3RA 2VFSA 5I1WA 4MLAA 1AHZA 3NRZB 2RK5A 1ZR6A 1W1LA 1HSKA 2BVHA 1AHUA 3S1CA 1N5XA 5I1VA 2VFRA 3FW7A 4DNSA 1DZNA 1W1OA 3HSUA 1FFVC 4HG0A 1VAOA 1W1RA 3HRDC 1N61C 1ZXIC 3NVYB 1I19A 5FXPA 3JS8A 2QPMA 2VFUA 2W55A 1F0XA 1E8FA 3NVWB 1VDVA 4EC3A 4PVKA 3S1EA 1JRPA 1DIQA 1SB3B 1JROA 2R8DA 5L6FA 2R2ZA 3D2JA 4PVJA 1E8GA 4PVEA 4PVHA 4PWCA 2W3RA 2W3SA 4ZOHB 5AE3A 3S1DA 4PWBA 3AM9A 1DIIA 2NQWA 3ETRB 3TSHA 3POPA 4O95A 1T3QC 5FXFA 1E0YA 1N62C 4PZFA 3SR6B 2BVFA 1MBTA 2AXRA 4UD8A 1N60C 3W8XA 2BVGA 1WVFA 3VTEA 4BC9A 1RM6B 2GQTA 2IPIA 5D79A 2I0KA 2VAOA 2GQUA 1W1MA 1W1SA 3C0PA 4BC7A 5L6GA 3PM9A 4BCAA 2YVSA 5HHZA 2P4PA 2Y08A 1QLTA 1FIQB 3W8ZA 5K8EA 3GSYA 3S1FA 3DEDA 3AMZA 1W1KA 1W1QA 1QLUA 1WVEA 2Q85A 5AE1A 3BW7A 4XLOA 2Y3SA 2P3HA 3D2HA 2OAIA 3D2DA 3DQ0A 1W1JA 2EXRA 1WYGA 3NVZB 3RJ8A 3LLBA 4OALA 4JAYA 5FXDA 4BBYA 2PLSA 2E3TA 3LAEA 3NVVB 5ADZA 2UUVA 1V97A 3KJMA 3EUB3 3FW8A 3RJAA 4JB1A 3NS1B 2VFTA 2QKNA 5G5GB 1UXYA 4PYTA 3B9JB 5HMRA 2VFVA 3FWAA 2P13A 3I99A 5FXEA 5AE2A 2Y4GA 2WDWA 1MBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ML8 A;  1AHV A;  3W8W A;  3TX1 A;  5G5H B;  2O3G A;  3FW9 A;  2W54 A;  1FFU C;  3AN1 A;  1FO4 A;  3PQB A;  1E8H A;  2Q4W A;  3TSJ A;  2PLI A;  5AWV A;  2MBR A;  1N5W C;  1N63 C;  5HQX A;  2Y3R A;  2VFS A;  5I1W A;  4MLA A;  1AHZ A;  3NRZ B;  2RK5 A;  1ZR6 A;  1W1L A;  1HSK A;  2BVH A;  1AHU A;  3S1C A;  1N5X A;  5I1V A;  2VFR A;  3FW7 A;  4DNS A;  1DZN A;  1W1O A;  3HSU A;  1FFV C;  4HG0 A;  1VAO A;  1W1R A;  3HRD C;  1N61 C;  1ZXI C;  3NVY B;  1I19 A;  5FXP A;  3JS8 A;  2QPM A;  2VFU A;  2W55 A;  1F0X A;  1E8F A;  3NVW B;  1VDV A;  4EC3 A;  4PVK A;  3S1E A;  1JRP A;  1DIQ A;  1SB3 B;  1JRO A;  2R8D A;  5L6F A;  2R2Z A;  3D2J A;  4PVJ A;  1E8G A;  4PVE A;  4PVH A;  4PWC A;  2W3R A;  2W3S A;  4ZOH B;  5AE3 A;  3S1D A;  4PWB A;  3AM9 A;  1DII A;  2NQW A;  3ETR B;  3TSH A;  3POP A;  4O95 A;  1T3Q C;  5FXF A;  1E0Y A;  1N62 C;  4PZF A;  3SR6 B;  2BVF A;  1MBT A;  2AXR A;  4UD8 A;  1N60 C;  3W8X A;  2BVG A;  1WVF A;  3VTE A;  4BC9 A;  1RM6 B;  2GQT A;  2IPI A;  5D79 A;  2I0K A;  2VAO A;  2GQU A;  1W1M A;  1W1S A;  3C0P A;  4BC7 A;  5L6G A;  3PM9 A;  4BCA A;  2YVS A;  5HHZ A;  2P4P A;  2Y08 A;  1QLT A;  1FIQ B;  3W8Z A;  5K8E A;  3GSY A;  3S1F A;  3DED A;  3AMZ A;  1W1K A;  1W1Q A;  1QLU A;  1WVE A;  2Q85 A;  5AE1 A;  3BW7 A;  4XLO A;  2Y3S A;  2P3H A;  3D2H A;  2OAI A;  3D2D A;  3DQ0 A;  1W1J A;  2EXR A;  1WYG A;  3NVZ B;  3RJ8 A;  3LLB A;  4OAL A;  4JAY A;  5FXD A;  4BBY A;  2PLS A;  2E3T A;  3LAE A;  3NVV B;  5ADZ A;  1V97 A;  3KJM A;  3EUB 3;  3FW8 A;  3RJA A;  4JB1 A;  3NS1 B;  2VFT A;  2QKN A;  5G5G B;  1UXY A;  4PYT A;  3B9J B;  5HMR A;  2VFV A;  3FWA A;  2P13 A;  3I99 A;  5FXE A;  5AE2 A;  2Y4G A;  2WDW A;  1MBB A; 
#chains in the Genus database with same CATH topology
 4ML8 A;  1AHV A;  3EJD B;  3TX1 A;  3W8W A;  5G5H B;  2O3G A;  3FW9 A;  2W54 A;  1FFU C;  3AN1 A;  1FO4 A;  3PQB A;  2UUU A;  1E8H A;  2Q4W A;  3TSJ A;  2PLI A;  5AWV A;  2MBR A;  1N5W C;  1N63 C;  5HQX A;  2Y3R A;  2VFS A;  5I1W A;  4MLA A;  1AHZ A;  3NRZ B;  2RK5 A;  1ZR6 A;  1W1L A;  1HSK A;  2BVH A;  1AHU A;  3S1C A;  1N5X A;  5I1V A;  2VFR A;  3FW7 A;  4DNS A;  1DZN A;  1W1O A;  3HSU A;  1FFV C;  4HG0 A;  1VAO A;  1W1R A;  3HRD C;  1N61 C;  1ZXI C;  3NVY B;  1I19 A;  5FXP A;  3JS8 A;  2QPM A;  2VFU A;  2W55 A;  1F0X A;  1E8F A;  3NVW B;  1VDV A;  4EC3 A;  4PVK A;  3S1E A;  1JRP A;  1DIQ A;  1SB3 B;  1JRO A;  2R8D A;  5L6F A;  2R2Z A;  3D2J A;  4PVJ A;  1E8G A;  4PVE A;  4PVH A;  4PWC A;  2W3R A;  2W3S A;  4ZOH B;  5AE3 A;  3S1D A;  4PWB A;  3AM9 A;  1DII A;  2NQW A;  3ETR B;  3TSH A;  3POP A;  4O95 A;  1T3Q C;  5FXF A;  1E0Y A;  1N62 C;  4PZF A;  3SR6 B;  2BVF A;  1MBT A;  2AXR A;  4UD8 A;  1N60 C;  3W8X A;  2BVG A;  1WVF A;  3VTE A;  4BC9 A;  1RM6 B;  2GQT A;  2IPI A;  5D79 A;  2I0K A;  2VAO A;  2GQU A;  1W1M A;  1W1S A;  3C0P A;  3EJB B;  4BC7 A;  5L6G A;  3PM9 A;  4BCA A;  2YVS A;  5HHZ A;  2P4P A;  2Y08 A;  1QLT A;  1FIQ B;  3W8Z A;  5K8E A;  3GSY A;  3S1F A;  3DED A;  3AMZ A;  1W1K A;  1W1Q A;  1QLU A;  1WVE A;  2Q85 A;  5AE1 A;  3BW7 A;  4XLO A;  2Y3S A;  2P3H A;  3D2H A;  2OAI A;  3D2D A;  3DQ0 A;  1W1J A;  2EXR A;  1WYG A;  3NVZ B;  3RJ8 A;  3LLB A;  4OAL A;  4JAY A;  5FXD A;  4BBY A;  2PLS A;  2E3T A;  3LAE A;  3NVV B;  5ADZ A;  2UUV A;  1V97 A;  3KJM A;  3EJE B;  3EUB 3;  3FW8 A;  3RJA A;  4JB1 A;  3NS1 B;  2VFT A;  2QKN A;  5G5G B;  1UXY A;  4PYT A;  3B9J B;  5HMR A;  2VFV A;  3FWA A;  2P13 A;  3I99 A;  5FXE A;  5AE2 A;  2Y4G A;  2WDW A;  1MBB A; 
#chains in the Genus database with same CATH homology
 4ML8 A;  1AHV A;  3W8W A;  3TX1 A;  5G5H B;  2O3G A;  3FW9 A;  2W54 A;  1FFU C;  3AN1 A;  1FO4 A;  3PQB A;  2UUU A;  1E8H A;  2Q4W A;  3TSJ A;  2PLI A;  5AWV A;  2MBR A;  1N5W C;  1N63 C;  5HQX A;  2Y3R A;  2VFS A;  5I1W A;  4MLA A;  1AHZ A;  3NRZ B;  2RK5 A;  1ZR6 A;  1W1L A;  1HSK A;  2BVH A;  1AHU A;  3S1C A;  1N5X A;  5I1V A;  2VFR A;  3FW7 A;  4DNS A;  1DZN A;  1W1O A;  3HSU A;  1FFV C;  4HG0 A;  1VAO A;  1W1R A;  3HRD C;  1N61 C;  1ZXI C;  3NVY B;  1I19 A;  5FXP A;  3JS8 A;  2QPM A;  2VFU A;  2W55 A;  1F0X A;  1E8F A;  3NVW B;  1VDV A;  4EC3 A;  4PVK A;  3S1E A;  1JRP A;  1DIQ A;  1SB3 B;  1JRO A;  2R8D A;  5L6F A;  2R2Z A;  3D2J A;  4PVJ A;  1E8G A;  4PVE A;  4PVH A;  4PWC A;  2W3R A;  2W3S A;  4ZOH B;  5AE3 A;  3S1D A;  4PWB A;  3AM9 A;  1DII A;  2NQW A;  3ETR B;  3TSH A;  3POP A;  4O95 A;  1T3Q C;  5FXF A;  1E0Y A;  1N62 C;  4PZF A;  3SR6 B;  2BVF A;  1MBT A;  2AXR A;  4UD8 A;  1N60 C;  3W8X A;  2BVG A;  1WVF A;  3VTE A;  4BC9 A;  1RM6 B;  2GQT A;  2IPI A;  5D79 A;  2I0K A;  2VAO A;  2GQU A;  1W1M A;  1W1S A;  3C0P A;  4BC7 A;  5L6G A;  3PM9 A;  4BCA A;  2YVS A;  5HHZ A;  2P4P A;  2Y08 A;  1QLT A;  1FIQ B;  3W8Z A;  5K8E A;  3GSY A;  3S1F A;  3DED A;  3AMZ A;  1W1K A;  1W1Q A;  1QLU A;  1WVE A;  2Q85 A;  5AE1 A;  3BW7 A;  4XLO A;  2Y3S A;  2P3H A;  3D2H A;  2OAI A;  3D2D A;  3DQ0 A;  1W1J A;  2EXR A;  1WYG A;  3NVZ B;  3RJ8 A;  3LLB A;  4OAL A;  4JAY A;  5FXD A;  4BBY A;  2PLS A;  2E3T A;  3LAE A;  3NVV B;  5ADZ A;  2UUV A;  1V97 A;  3KJM A;  3EUB 3;  3FW8 A;  3RJA A;  4JB1 A;  3NS1 B;  2VFT A;  2QKN A;  5G5G B;  1UXY A;  4PYT A;  3B9J B;  5HMR A;  2VFV A;  3FWA A;  2P13 A;  3I99 A;  5FXE A;  5AE2 A;  2Y4G A;  2WDW A;  1MBB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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